Publications

5418 publications

Genomic analyses elucidate the causes and consequences of breakdown of distyly inLinum trigynum
Gutiérrez-Valencia J, Zervakis PI, Postel Z, ..., Arroyo J, Slotte T
- - (-) - [2023-11-17; online 2023-11-17]
SciLifeLab Fellow Tanja Slotte
Novel styryl-thiazole hybrids as potential anti-Alzheimer's agents.
Gouleni N, Di Rienzo A, Yılmaz A, ..., Vassiliou S, Cacciatore I
RSC Med Chem 14 (11) 2315-2326 [2023-11-15; online 2023-09-21]
Adil Mardinoglu SciLifeLab Fellow
Core genes driving climate adaptation in plants
Yeaman S, Whiting J, Booker T, ..., Wright S, Zhou L
- - (-) - [2023-11-10; online 2023-11-10]
Pascal Milesi SciLifeLab Fellow
SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation.
Chen CW, Zhang L, Dutta R, ..., Sperling AS, Goodell MA
Cell Stem Cell 30 (11) 1503-1519.e8 [2023-11-02; online 2023-10-19]
Abhishek Niroula DDLS Fellow
Functional and molecular profiling of hematopoietic stem cells during regeneration.
Rydström A, Grahn THM, Niroula A, ..., Larsson J, Karlsson S
Exp. Hematol. 127 (-) 40-51 [2023-11-00; online 2023-09-04]
Abhishek Niroula DDLS Fellow
A novel kleptoplastidic symbiosis revealed in the marine centrohelid Meringosphaera with evidence of genetic integration.
Sørensen MES, Zlatogursky VV, Onuţ-Brännström I, ..., Foster RA, Burki F
Curr. Biol. 33 (17) 3571-3584.e6 [2023-09-11; online 2023-08-02]
Fabien Burki SciLifeLab Fellow
Persistent immunosuppressive effects of dibutyl phthalate exposure in adult male mice.
Pierozan P, Källsten L, Theodoropoulou E, Almamoun R, Karlsson O
Sci. Total Environ. 878 (-) 162741 [2023-06-20; online 2023-03-11]
Oskar Karlsson SciLifeLab Fellow
Obesity-induced inflammation exacerbates clonal hematopoiesis.
Pasupuleti SK, Ramdas B, Burns SS, ..., Natarajan P, Kapur R
J. Clin. Invest. 133 (11) - [2023-06-01; online 2023-06-01]
Abhishek Niroula DDLS Fellow
Membranes in focus.
Sezgin E, Levental I
Biophys. J. - (-) - [2023-05-19; online 2023-05-19]
Erdinc Sezgin SciLifeLab Fellow
Prediction of risk for myeloid malignancy in clonal hematopoiesis.
Weeks LD, Niroula A, Neuberg D, ..., Natarajan P, Ebert BL
NEJM Evid 2 (5) - [2023-05-00; online 2023-04-25]
Abhishek Niroula DDLS Fellow
Development of top-down cortical propagations in youth.
Pines A, Keller AS, Larsen B, ..., Fair DA, Satterthwaite TD
Neuron 111 (8) 1316-1330.e5 [2023-04-19; online 2023-02-17]
DDLS Fellow Jacob W Vogel
A GC-centered view of 3D genome organization.
Bouwman BA, Crosetto N, Bienko M
Curr. Opin. Genet. Dev. 78 (-) 102020 [2023-02-00; online 2023-01-05]
Magda Bienko
Editorial: Effects of hormonal contraceptives on the brain.
Pletzer B, Comasco E, Hidalgo-Lopez E, Lacreuse A, Derntl B
Front Endocrinol (Lausanne) 14 (-) 1129203 [2023-01-31; online 2023-01-31]
Erika Comasco SciLifeLab Fellow
Obesity-Associated Neurodegeneration Pattern Mimics Alzheimer's Disease in an Observational Cohort Study.
Morys F, Potvin O, Zeighami Y, ..., Dagher A, Alzheimer’s Disease Neuroimaging Initiative
J. Alzheimers Dis. 91 (3) 1059-1071 [2022-12-25; online 2022-12-25]
DDLS Fellow Jacob W Vogel
Development of l-Dopa-containing diketopiperazines as blood-brain barrier shuttle.
Cornacchia C, Marinelli L, Di Rienzo A, ..., Di Stefano A, Cacciatore I
Eur J Med Chem 243 (-) 114746 [2022-12-05; online 2022-09-08]
Adil Mardinoglu SciLifeLab Fellow
Genomic Profiling Identifies Putative Pathogenic Alterations in NSCLC Brain Metastases.
Nicoś M, Harbers L, Patrucco E, ..., Ambrogio C, Crosetto N
JTO Clin Res Rep 3 (12) 100435 [2022-12-00; online 2022-11-11]
Magda Bienko
Genomic trajectories of a near-extinction event in the Chatham Island black robin.
von Seth J, van der Valk T, Lord E, ..., Robertson BC, Dussex N
BMC Genomics 23 (1) 747 [2022-11-10; online 2022-11-10]
DDLS Fellow Tom van der Valk
Genomic analyses of the Linum distyly supergene reveal convergent evolution at the molecular level.
Gutiérrez-Valencia J, Fracassetti M, Berdan EL, ..., Arroyo J, Slotte T
Curr. Biol. 32 (20) 4360-4371.e6 [2022-10-24; online 2022-09-09]
SciLifeLab Fellow Tanja Slotte
DNA promoter hypermethylation of melanocyte lineage genes determines melanoma phenotype.
Sanna A, Phung B, Mitra S, ..., Pietras K, Jönsson G
JCI Insight 7 (19) - [2022-10-10; online 2022-10-10]
Chronic hyperinsulinemia promotes human hepatocyte senescence.
Baboota RK, Spinelli R, Erlandsson MC, ..., Kahn CR, Smith U
Mol Metab 64 (-) 101558 [2022-10-00; online 2022-07-21]
Adil Mardinoglu SciLifeLab Fellow
EukProt: A database of genome-scale predicted proteins across the diversity of eukaryotes
Richter DJ, Berney C, Strassert JFH, ..., Burki F, de Vargas C
- 2 (-) - [2022-09-20; online 2022-09-20]
Fabien Burki SciLifeLab Fellow
Evolutionary consequences of genomic deletions and insertions in the woolly mammoth genome.
van der Valk T, Dehasque M, Chacón-Duque JC, ..., Díez-Del-Molino D, Dalén L
iScience 25 (8) 104826 [2022-08-19; online 2022-08-01]
DDLS Fellow Tom van der Valk
A Universal Language for Finding Mass Spectrometry Data Patterns
Jarmusch AK, Aron AT, Petras D, ..., Dorrestein PC, Wang M
- - (-) - [2022-08-07; online 2022-08-07]
Daniel Globisch SciLifeLab Fellow
The anti-inflammatory peptide Catestatin blocks chemotaxis.
Muntjewerff EM, Parv K, Mahata SK, ..., Christoffersson G, van den Bogaart G
J Leukoc Biol 112 (2) 273-278 [2022-08-00; online 2021-12-22]
Gustaf Christoffersson SciLifeLab Fellow
Issues and recommendations for the residual approach to quantifying cognitive resilience and reserve.
Elman JA, Vogel JW, Bocancea DI, ..., Kremen WS, Alzheimer’s Disease Neuroimaging Initiative
Alzheimers Res Ther 14 (1) 102 [2022-07-25; online 2022-07-25]
DDLS Fellow Jacob W Vogel
Robust and integrative Bayesian neural networks for likelihood-free parameter inference
Wrede F, Eriksson R, Jiang R, ..., Hellander A, Singh P
- - (-) - [2022-07-18; online 2022-07-18]
Prashant Singh SciLifeLab Fellow
FOXO1 and FOXO3 Cooperatively Regulate Innate Lymphoid Cell Development.
Luu TT, Søndergaard JN, Peña-Pérez L, ..., Månsson R, Kadri N
Front Immunol 13 (-) 854312 [2022-06-09; online 2022-06-09]
Claudia Kutter SciLifeLab Fellow
Potato genomes pave the way to crop improvement.
Gutiérrez-Valencia J, Slotte T
Nature 606 (7914) 472-473 [2022-06-00; online 2022-06-09]
SciLifeLab Fellow Tanja Slotte
Impact of Genome Reduction in Microsporidia.
Jespersen N, Monrroy L, Barandun J
Exp Suppl 114 (-) 1-42 [2022-05-12; online 2022-05-12]
Jonas Barandun SciLifeLab Fellow
Scalable federated machine learning with FEDn
Ekmefjord M, Ait-Mlouk A, Alawadi S, ..., Toor S, Hellander A
- - (-) - [2022-05-00; online 2022-05-00]
Prashant Singh SciLifeLab Fellow
Estimating Alpha, Beta, and Gamma Diversity Through Deep Learning.
Andermann T, Antonelli A, Barrett RL, Silvestro D
Front Plant Sci 13 (-) 839407 [2022-04-19; online 2022-04-19]
DDLS Fellow Tobias Andermann
Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase.
Nain-Perez A, Foller Füchtbauer A, Håversen L, ..., Uhlen M, Grøtli M
Eur J Med Chem 234 (-) 114270 [2022-04-15; online 2022-03-08]
Adil Mardinoglu SciLifeLab Fellow
Differentiating amyloid beta spread in autosomal dominant and sporadic Alzheimer's disease.
Levitis E, Vogel JW, Funck T, ..., Dominantly Inherited Alzheimer Network , Alzheimer’s Disease Neuroimaging Initiative
Brain Commun 4 (3) fcac085 [2022-04-13; online 2022-04-13]
DDLS Fellow Jacob W Vogel
Grey matter correlates of affective and somatic symptoms of premenstrual dysphoric disorder.
Dubol M, Wikström J, Lanzenberger R, ..., Sundström-Poromaa I, Comasco E
Sci Rep 12 (1) 5996 [2022-04-09; online 2022-04-09]
Erika Comasco SciLifeLab Fellow
PET-CT imaging of pulmonary inflammation using [68Ga]Ga-DOTA-TATE.
Puuvuori E, Liggieri F, Velikyan I, ..., Perchiazzi G, Eriksson O
EJNMMI Res 12 (1) 19 [2022-04-08; online 2022-04-08]
Olof Eriksson SciLifeLab Fellow
IgE cross-linking induces activation of human and mouse mast cell progenitors.
Méndez-Enríquez E, Salomonsson M, Eriksson J, ..., Sellin ME, Hallgren J
J. Allergy Clin. Immunol. 149 (4) 1458-1463 [2022-04-00; online 2021-09-04]
Mikael Sellin SciLifeLab Fellow
Brain charts for the human lifespan.
Bethlehem RAI, Seidlitz J, White SR, ..., Bullmore ET, Alexander-Bloch AF
Nature 604 (7906) 525-533 [2022-04-00; online 2022-04-06]
DDLS Fellow Jacob W Vogel
Genome-wide association study on 13 167 individuals identifies regulators of blood CD34+cell levels.
Lopez de Lapuente Portilla A, Ekdahl L, Cafaro C, ..., Stefansson K, Nilsson B
Blood 139 (11) 1659-1669 [2022-03-17; online 2022-01-11]
Abhishek Niroula DDLS Fellow
Correction to: Toxicogenomics directory of chemically exposed human hepatocytes.
Grinberg M, Stöber RM, Edlund K, ..., Rahnenführer J, Hengstler JG
Arch. Toxicol. 96 (3) 945-946 [2022-03-00; online 2022-02-01]
Adil Mardinoglu SciLifeLab Fellow
White matter microstructure and volume correlates of premenstrual dysphoric disorder.
Gu X, Dubol M, Stiernman L, ..., Sundström-Poromaa I, Comasco E
J Psychiatry Neurosci 47 (1) E67-E76 [2022-02-23; online 2022-02-23]
Erika Comasco SciLifeLab Fellow
Genomics and adaptation in forest ecosystems.
Neophytou C, Heer K, Milesi P, ..., Rellstab C, Gugerli F
Tree Genet Genomes 18 (2) 12 [2022-02-09; online 2022-02-09]
Pascal Milesi SciLifeLab Fellow
RNA gradients: Shapers of 3D genome architecture.
Bouwman BAM, Crosetto N, Bienko M
Curr Opin Cell Biol 74 (-) 7-12 [2022-02-00; online 2022-01-05]
Magda Bienko
Role of Cellular Metabolism during Candida-Host Interactions.
Pellon A, Begum N, Sadeghi Nasab SD, ..., Shoaie S, Moyes DL
Pathogens 11 (2) - [2022-01-28; online 2022-01-28]
Saeed Shoaie SciLifeLab Fellow
Genome-wide annotation of protein-coding genes in pig.
Karlsson M, Sjöstedt E, Oksvold P, ..., Luo Y, Uhlen M
BMC Biol. 20 (1) 25 [2022-01-25; online 2022-01-25]
Adil Mardinoglu SciLifeLab Fellow
Association of clonal hematopoiesis with chronic obstructive pulmonary disease.
Miller PG, Qiao D, Rojas-Quintero J, ..., Ebert BL, COPDGene Study Investigators, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine Consortium
Blood 139 (3) 357-368 [2022-01-20; online 2021-12-03]
Abhishek Niroula DDLS Fellow
Putative regulation of macrophage-mediated inflammation by catestatin.
Muntjewerff EM, Christoffersson G, Mahata SK, van den Bogaart G
Trends Immunol. 43 (1) 41-50 [2022-01-00; online 2021-11-27]
Gustaf Christoffersson SciLifeLab Fellow
Therapeutic Potential of Ferulic Acid in Alzheimer's Disease.
Turkez H, Arslan ME, Barboza JN, ..., de Sousa DP, Mardinoğlu A
Curr Drug Deliv 19 (8) 860-873 [2021-12-30; online 2021-12-30]
Adil Mardinoglu SciLifeLab Fellow
Potential of [11C]UCB-J as a PET tracer for islets of Langerhans.
Puuvuori E, Rokka J, Carlsson PO, ..., Eriksson J, Eriksson O
Sci Rep 11 (1) 24466 [2021-12-28; online 2021-12-28]
Olof Eriksson SciLifeLab Fellow
Genomic and niche divergence in an Amazonian palm species complex
Bacon CD, Roncal J, Andermann T, ..., Tunarosa N, Antonelli A
- 197 (4) 498-512 [2021-11-29; online 2021-05-10]
DDLS Fellow Tobias Andermann
MapToCleave: High-throughput profiling of microRNA biogenesis in living cells.
Kang W, Fromm B, Houben AJ, ..., Biryukova I, Friedländer MR
Cell Reports 37 (7) 110015 [2021-11-16; online 2021-11-18]
Marc Friedländer SciLifeLab Fellow
A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling.
Meineke B, Heimgärtner J, Craig AJ, ..., Moodie LWK, Elsässer SJ
Front Chem 9 (-) 768535 [2021-11-11; online 2021-11-11]
SciLifeLab Fellow Simon Elsässer
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 9: Polymyxins: colistin.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06861 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 8: Pleuromutilins: tiamulin and valnemulin.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06860 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 5: Lincosamides: lincomycin.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06856 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 4: β-Lactams: amoxicillin and penicillin V.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06855 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 3: Amprolium.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06854 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 13: Diaminopyrimidines: trimethoprim.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06865 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 11: Sulfonamides.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06863 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
A practical guide to large-scale docking.
Bender BJ, Gahbauer S, Luttens A, ..., Irwin JJ, Shoichet BK
Nat Protoc 16 (10) 4799-4832 [2021-10-00; online 2021-09-24]
Jens Carlsson SciLifeLab Fellow
Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69.
Persson J, Puuvuori E, Zhang B, ..., Eriksson O, Löfblom J
Sci Rep 11 (1) 19151 [2021-09-27; online 2021-09-27]
Olof Eriksson SciLifeLab Fellow
Selection on accessible chromatin regions in Capsella grandiflora.
Horvath R, Josephs EB, Pesquet E, ..., Scofield D, Slotte T
Mol. Biol. Evol. - (-) - [2021-09-08; online 2021-09-08]
SciLifeLab Fellow Tanja Slotte
Anticancer effects of novel NSAIDs derivatives on cultured human glioblastoma cells.
Özdemir Ö, Marinelli L, Cacciatore I, ..., Mardinoglu A, Turkez H
Z Naturforsch C J Biosci 76 (7-8) 329-335 [2021-07-27; online 2020-09-05]
Adil Mardinoglu SciLifeLab Fellow
Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure.
Yu B, Roberts MB, Raffield LM, ..., Eaton CB, National Heart, Lung, and Blood Institute TOPMed Consortium
J. Am. Coll. Cardiol. 78 (1) 42-52 [2021-07-06; online 2021-07-03]
Abhishek Niroula DDLS Fellow
DNA Blocks the Lethal Effect of Human Beta-Defensin 2 Against Neisseria meningitidis.
Wassing GM, Lidberg K, Sigurlásdóttir S, ..., Jonas K, Jonsson AB
Front Microbiol 12 (-) 697232 [2021-06-30; online 2021-06-30]
Kristina Jonas SciLifeLab Fellow
Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source.
Douangamath A, Powell A, Fearon D, ..., Gorrie-Stone T, von Delft F
J Vis Exp - (171) - [2021-05-29; online 2021-05-29]
DDLS Fellow Nicholas Pearce
Perivascular Macrophages Regulate Blood Flow Following Tissue Damage.
Vågesjö E, Parv K, Ahl D, ..., Christoffersson G, Phillipson M
Circ. Res. 128 (11) 1694-1707 [2021-05-28; online 2021-04-21]
Gustaf Christoffersson SciLifeLab Fellow
Phagocytosis and Efferocytosis by Resident Macrophages in the Mouse Pancreas.
Parv K, Westerlund N, Merchant K, ..., Lindsay RS, Christoffersson G
Front Endocrinol (Lausanne) 12 (-) 606175 [2021-05-25; online 2021-05-25]
Gustaf Christoffersson SciLifeLab Fellow
The human exposome and health in the Anthropocene.
Karlsson O, Rocklöv J, Lehoux AP, ..., Blunt MJ, Birnbaum LS
Int J Epidemiol 50 (2) 378-389 [2021-05-17; online 2020-12-23]
Oskar Karlsson SciLifeLab Fellow
Germline variants at SOHLH2 influence multiple myeloma risk.
Duran-Lozano L, Thorleifsson G, Lopez de Lapuente Portilla A, ..., Stefansson K, Nilsson B
Blood Cancer J 11 (4) 76 [2021-04-19; online 2021-04-19]
Abhishek Niroula DDLS Fellow
A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation.
Regadas I, Dahlberg O, Vaid R, ..., Wen J, Mannervik M
Mol. Cell 81 (8) 1766-1780.e10 [2021-04-15; online 2021-02-24]
SciLifeLab Fellow Sebastian Deindl
Addressing the heterogeneity in liver diseases using biological networks.
Lam S, Doran S, Yuksel HH, ..., Uhlen M, Mardinoglu A
Brief. Bioinformatics 22 (2) 1751-1766 [2021-03-22; online 2020-03-24]
Adil Mardinoglu SciLifeLab Fellow
Ulipristal Acetate for Treatment of Premenstrual Dysphoric Disorder: A Proof-of-Concept Randomized Controlled Trial
Comasco E, Kopp Kallner H, Bixo M, ..., Epperson CN, Sundström-Poromaa I
AJP 178 (3) 256-265 [2021-03-01; online 2021-03-01]
Erika Comasco SciLifeLab Fellow
No evidence for a placental microbiome in human pregnancies at term.
Sterpu I, Fransson E, Hugerth LW, ..., Wiberg-Itzel E, Schuppe-Koistinen I
Am J Obstet Gynecol 224 (3) 296.e1-296.e23 [2021-03-00; online 2020-08-29]
DDLS Fellow Luisa Hugerth
3D-printing of solid lipid tablets from emulsion gels
Johannesson J, Khan J, Hubert M, Teleki A, Bergström CAS
Int J Pharm 597 (-) 120304 [2021-03-00; online 2021-03-00]
Alexandra Teleki SciLifeLab Fellow
Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.
Hewitt G, Borel V, Segura-Bayona S, ..., Deindl S, Boulton SJ
Mol. Cell 81 (4) 767-783.e11 [2021-02-18; online 2020-12-16]
SciLifeLab Fellow Sebastian Deindl
Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women.
Honigberg MC, Zekavat SM, Niroula A, ..., NHLBI Trans-Omics for Precision Medicine Program , Natarajan P
Circulation 143 (5) 410-423 [2021-02-02; online 2020-11-09]
Abhishek Niroula DDLS Fellow
Epidemiological modeling in StochSS Live!
Jiang R, Jacob B, Geiger M, ..., Hellander A, Petzold L
Bioinformatics - (-) - [2021-01-29; online 2021-01-29]
Prashant Singh SciLifeLab Fellow
Neuroimaging the menstrual cycle: A multimodal systematic review.
Dubol M, Epperson CN, Sacher J, ..., Sundström-Poromaa I, Comasco E
Front Neuroendocrinol 60 (-) 100878 [2021-01-00; online 2020-10-22]
Erika Comasco SciLifeLab Fellow
Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development.
Malkani S, Chin CR, Cekanaviciute E, ..., Mason CE, Beheshti A
Cell Reports 33 (10) 108448 [2020-12-08; online 2020-11-25]
Marc Friedländer SciLifeLab Fellow
The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19.
Consiglio CR, Cotugno N, Sardh F, ..., Palma P, Brodin P
Cell 183 (4) 968-981.e7 [2020-11-12; online 2020-09-06]
Camila Consiglio DDLS Fellow
Potential Anticancer Effect of Carvacrol Codrugs on Human Glioblastoma Cells.
Yazici A, Marinelli L, Cacciatore I, ..., Mardinoğlu A, Türkez H
Curr Drug Deliv 18 (3) 350-356 [2020-10-29; online 2020-10-29]
Adil Mardinoglu SciLifeLab Fellow
Progesterone - Friend or foe?
Sundström-Poromaa I, Comasco E, Sumner R, Luders E
Front Neuroendocrinol 59 (-) 100856 [2020-10-00; online 2020-07-28]
Erika Comasco SciLifeLab Fellow
Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19.
Rodriguez L, Pekkarinen PT, Lakshmikanth T, ..., Kekäläinen E, Brodin P
Cell Rep Med 1 (5) 100078 [2020-08-25; online 2020-08-05]
Camila Consiglio DDLS Fellow
Predatory colponemids are the sister group to all other alveolates.
Tikhonenkov DV, Strassert JFH, Janouškovec J, ..., Burki F, Keeling PJ
Mol. Phylogenet. Evol. 149 (-) 106839 [2020-08-00; online 2020-04-21]
Fabien Burki SciLifeLab Fellow
Quo vadis microRNAs?
Fromm B, Keller A, Yang X, ..., Peterson KJ, Griffiths-Jones S
Trends in Genetics 36 (7) 461-463 [2020-07-00; online 2020-04-16]
Marc Friedländer SciLifeLab Fellow
Identification of germline variants in adults with hemophagocytic lymphohistiocytosis.
Miller PG, Niroula A, Ceremsak JJ, ..., Berliner N, Ebert BL
Blood Adv 4 (5) 925-929 [2020-03-10; online 2020-03-10]
Abhishek Niroula DDLS Fellow
A Guide to Carrying Out a Phylogenomic Target Sequence Capture Project.
Andermann T, Torres Jiménez MF, Matos-Maraví P, ..., Bacon CD, Antonelli A
Front Genet 10 (-) 1407 [2020-02-21; online 2020-02-21]
DDLS Fellow Tobias Andermann
Abundance and diversity of resistomes differ between healthy human oral cavities and gut.
Carr VR, Witherden EA, Lee S, ..., Gomez-Cabrero D, Moyes DL
Nat Commun 11 (1) 693 [2020-02-04; online 2020-02-04]
Saeed Shoaie SciLifeLab Fellow
The molecular basis for sugar import in malaria parasites.
Qureshi AA, Suades A, Matsuoka R, ..., Delemotte L, Drew D
Nature 578 (7794) 321-325 [2020-02-00; online 2020-01-29]
Lucie Delemotte SciLifeLab Fellow
Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D.
Sayitoglu EC, Georgoudaki AM, Chrobok M, ..., Sutlu T, Duru AD
Front Immunol 11 (-) 40 [2020-01-28; online 2020-01-28]
Adil Mardinoglu SciLifeLab Fellow
MirGeneDB 2.0: the metazoan microRNA complement.
Fromm B, Domanska D, Høye E, ..., Friedländer MR, Peterson KJ
Nucleic Acids Res. 48 (D1) D1172 [2020-01-08; online 2019-10-24]
Marc Friedländer SciLifeLab Fellow
The New Tree of Eukaryotes.
Burki F, Roger AJ, Brown MW, Simpson AGB
Trends in Ecology & Evolution 35 (1) 43-55 [2020-01-00; online 2019-10-09]
Fabien Burki SciLifeLab Fellow
A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart.
Asp M, Giacomello S, Larsson L, ..., Sylvén C, Lundeberg J
Cell 179 (7) 1647-1660.e19 [2019-12-12; online 2019-12-14]
Magda Bienko SciLifeLab Fellow
Enrichment of oral microbiota in early cystic precursors to invasive pancreatic cancer.
Gaiser RA, Halimi A, Alkharaan H, ..., Del Chiaro M, Sällberg Chen M
Gut 68 (12) 2186-2194 [2019-12-00; online 2019-03-14]
DDLS Fellow Luisa Hugerth
Association of PTHrP levels in CSF with Alzheimer's disease biomarkers.
Kushnir MM, Michno W, Rockwood AL, ..., Strathmann FG, Hanrieder J
Clin Mass Spectrom 14 Pt B (-) 124-129 [2019-11-00; online 2018-10-09]
SciLifeLab Fellow Wojciech Michno
Sharing Data from Molecular Simulations.
Abraham M, Apostolov R, Barnoud J, ..., Woods C, Zhmurov A
J Chem Inf Model 59 (10) 4093-4099 [2019-10-28; online 2019-10-11]
Lucie Delemotte SciLifeLab Fellow
Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut.
Bakkeren E, Huisman JS, Fattinger SA, ..., Diard M, Hardt WD
Nature 573 (7773) 276-280 [2019-09-00; online 2019-09-04]
Mikael Sellin SciLifeLab Fellow
Nanoscale dynamics of cholesterol in the cell membrane.
Pinkwart K, Schneider F, Lukoseviciute M, ..., Eggeling C, Sezgin E
J. Biol. Chem. 294 (34) 12599-12609 [2019-08-23; online 2019-07-03]
Erdinc Sezgin SciLifeLab Fellow
Tools for Bioimaging Pancreatic β Cells in Diabetes.
Kang NY, Soetedjo AAP, Amirruddin NS, ..., Eriksson O, Teo AKK
Trends in molecular medicine 25 (8) 708-722 [2019-08-00; online 2019-06-06]
Olof Eriksson SciLifeLab Fellow
Amyloid fibril polymorphism and cell-specific toxicity in vivo.
Jonson M, Nyström S, Sandberg A, ..., Thor S, Hammarström P
Amyloid 26 (sup1) 136-137 [2019-07-26; online 2019-07-26]
SciLifeLab Fellow Wojciech Michno
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis.
Smillie CS, Biton M, Ordovas-Montanes J, ..., Xavier RJ, Regev A
Cell 178 (3) 714-730.e22 [2019-07-25; online 2019-07-28]
Sanja Vickovic SciLifeLab Fellow
The Potential Use of Metabolic Cofactors in Treatment of NAFLD.
Mardinoglu A, Ural D, Zeybel M, ..., Uhlén M, Borén J
Nutrients 11 (7) 1578 [2019-07-12; online 2019-07-12]
Adil Mardinoglu SciLifeLab Fellow
Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection.
Zychlinsky Scharff A, Rousseau M, Lacerda Mariano L, ..., Duffy D, Ingersoll MA
JCI Insight 5 (13) - [2019-05-30; online 2019-05-30]
Camila Consiglio DDLS Fellow
Receptor-Independent Transfer of Low Density Lipoprotein Cargo to Biomembranes.
Axmann M, Sezgin E, Karner A, ..., Stangl H, Plochberger B
Nano Lett. 19 (4) 2562-2567 [2019-04-10; online 2019-03-08]
Erdinc Sezgin SciLifeLab Fellow
System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection.
Garcia-Moreno M, Noerenberg M, Ni S, ..., Mohammed S, Castello A
Mol. Cell 74 (1) 196-211.e11 [2019-04-04; online 2019-02-21]
SciLifeLab Fellow Vicent Pelechano
Case Reports of Pre-clinical Replication Studies in Metabolism and Diabetes.
von Herrath M, Pagni PP, Grove K, ..., Karlsen AE, Petersen JS
Cell Metab. 29 (4) 795-802 [2019-04-02; online 2019-03-14]
Gustaf Christoffersson SciLifeLab Fellow
Measuring nanoscale diffusion dynamics in cellular membranes with super-resolution STED-FCS.
Sezgin E, Schneider F, Galiani S, ..., Lagerholm BC, Eggeling C
Nat Protoc 14 (4) 1054-1083 [2019-04-00; online 2019-03-06]
Erdinc Sezgin SciLifeLab Fellow
Plant microRNAs in human sera are likely contaminants.
Fromm B, Kang W, Rovira C, ..., Friedländer MR, Tosar JP
J Nutr Biochem 65 (-) 139-140 [2019-03-00; online 2018-09-05]
Marc Friedländer SciLifeLab Fellow
Structural Patching Fosters Divergence of Mitochondrial Ribosomes.
Petrov AS, Wood EC, Bernier CR, ..., Brown A, Amunts A
Mol. Biol. Evol. 36 (2) 207-219 [2019-02-01; online 2018-12-06]
Alexey Amunts SciLifeLab Fellow
Ascetosporea.
Bass D, Ward GM, Burki F
Curr. Biol. 29 (1) R7-R8 [2019-01-07; online 2019-01-09]
Fabien Burki SciLifeLab Fellow
A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System.
de Jong JW, Afjei SA, Pollak Dorocic I, ..., Deisseroth K, Lammel S
Neuron 101 (1) 133-151.e7 [2019-01-02; online 2018-11-29]
Iskra Pollak Dorocic SciLifeLab Fellow
Allele Phasing Greatly Improves the Phylogenetic Utility of Ultraconserved Elements.
Andermann T, Fernandes AM, Olsson U, ..., Faircloth BC, Antonelli A
Syst. Biol. 68 (1) 32-46 [2019-01-01; online 2018-05-18]
DDLS Fellow Tobias Andermann
Phylogenomics supports the monophyly of the Cercozoa.
Irwin NAT, Tikhonenkov DV, Hehenberger E, ..., Burki F, Keeling PJ
Mol. Phylogenet. Evol. 130 (-) 416-423 [2019-01-00; online 2018-10-11]
Fabien Burki SciLifeLab Fellow
miRTrace reveals the organismal origins of microRNA sequencing data.
Kang W, Eldfjell Y, Fromm B, ..., Biryukova I, Friedländer MR
Genome Biol. 19 (1) 213 [2018-12-04; online 2018-12-04]
Marc Friedländer SciLifeLab Fellow
Forces drive basement membrane invasion in Caenorhabditis elegans.
Cáceres R, Bojanala N, Kelley LC, ..., Sherwood DR, Plastino J
Proc. Natl. Acad. Sci. U.S.A. 115 (45) 11537-11542 [2018-11-06; online 2018-10-22]
Ilaria Testa SciLifeLab Fellow
microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function.
Langlet F, Tarbier M, Haeusler RA, ..., Friedländer MR, Accili D
Mol Metab 17 (-) 49-60 [2018-11-00; online 2018-08-11]
Marc Friedländer SciLifeLab Fellow
Uncovering the regional localization of inhaled salmeterol retention in the lung.
Bäckström E, Hamm G, Nilsson A, ..., Goodwin RJA, Fridén M
Drug Deliv 25 (1) 838-845 [2018-11-00; online 2018-03-29]
Affiliated researcher
Transfection of crayfish hematopoietic tissue cells.
Shi H, Ruan L, Söderhäll I, Söderhäll K, Xu X
Dev. Comp. Immunol. 88 (-) 70-76 [2018-11-00; online 2018-07-09]
Affiliated researcher
Barcoded solid-phase RNA capture for Spatial Transcriptomics profiling in mammalian tissue sections.
Salmén F, Ståhl PL, Mollbrink A, ..., Frisén J, Lundeberg J
Nat Protoc 13 (11) 2501-2534 [2018-11-00; online 2018-10-26]
Sanja Vickovic SciLifeLab Fellow
Detection of post-translational modifications using solid-phase proximity ligation assay.
Oliveira FMS, Mereiter S, Lönn P, ..., Reis CA, Kamali-Moghaddam M
N Biotechnol 45 (-) 51-59 [2018-10-25; online 2017-10-31]
Affiliated researcher
A myopic perspective on the future of protein diagnostics.
Landegren U, Al-Amin RA, Björkesten J
N Biotechnol 45 (-) 14-18 [2018-10-25; online 2018-01-05]
Affiliated researcher
Rapid Isolation of the Mitoribosome from HEK Cells.
Aibara S, Andréll J, Singh V, Amunts A
J Vis Exp - (140) - [2018-10-04; online 2018-10-04]
Alexey Amunts SciLifeLab Fellow
Reconstitution of immune cell interactions in free-standing membranes.
Jenkins E, Santos AM, O'Brien-Ball C, ..., Eggeling C, Sezgin E
J. Cell. Sci. 132 (4) - [2018-10-02; online 2018-10-02]
Erdinc Sezgin SciLifeLab Fellow
High Cell Density Perfusion Culture has a Maintained Exoproteome and Metabolome.
Zamani L, Lundqvist M, Zhang Y, ..., Rockberg J, Chotteau V
Biotechnol J 13 (10) e1800036 [2018-10-00; online 2018-07-13]
Adil Mardinoglu SciLifeLab Fellow
Bioanalytical advantages of a novel recombinant apyrase enzyme in ATP-based bioluminescence methods.
Pavankumar AR, Zelenin S, Lundin A, ..., Achour A, Russom A
Anal. Chim. Acta 1025 (-) 118-123 [2018-09-26; online 2018-04-26]
Affiliated researcher
Effects of Design Choices on the Stiffness of Wireframe DNA Origami Structures.
Benson E, Mohammed A, Rayneau-Kirkhope D, ..., Orponen P, Högberg B
ACS Nano 12 (9) 9291-9299 [2018-09-25; online 2018-09-06]
Erik Benson SciLifeLab Fellow
Phylogeny and Systematics of Kewa (Kewaceae)
Thulin M, Larsson A, Edwards EJ, Moore AJ
Systematic Botany 43 (3) 689-700 [2018-09-10; online 2018-09-10]
Affiliated researcher
Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells.
Srpan K, Ambrose A, Karampatzakis A, ..., Önfelt B, Davis DM
J. Cell Biol. 217 (9) 3267-3283 [2018-09-03; online 2018-07-02]
Affiliated researcher
The pro-inflammatory role of platelets in cancer.
Olsson AK, Cedervall J
Platelets 29 (6) 569-573 [2018-09-00; online 2018-03-27]
Affiliated researcher
The downfall of TBA-354 - a possible explanation for its neurotoxicity via mass spectrometric imaging.
Ntshangase S, Shobo A, Kruger HG, ..., Govender T, Baijnath S
Xenobiotica 48 (9) 938-944 [2018-09-00; online 2017-10-13]
Affiliated researcher
The Protozoan Parasite Toxoplasma gondii Selectively Reprograms the Host Cell Translatome.
Leroux LP, Lorent J, Graber TE, ..., Larsson O, Jaramillo M
Infect. Immun. 86 (9) - [2018-09-00; online 2018-08-22]
Affiliated researcher
Targeting ATR in cancer.
Lecona E, Fernandez-Capetillo O
Nat. Rev. Cancer 18 (9) 586-595 [2018-09-00; online 2018-06-15]
Affiliated researcher
Survival of Campylobacter jejuni and Campylobacter coli water isolates in lake and well water.
Nilsson A, Johansson C, Skarp A, ..., Bertilsson S, Rautelin H
APMIS 126 (9) 762-770 [2018-09-00; online 2018-08-31]
Affiliated researcher
Multi-ethnic genome-wide association study for atrial fibrillation.
Roselli C, Chaffin MD, Weng LC, ..., Lunetta KL, Ellinor PT
Nat. Genet. 50 (9) 1225-1233 [2018-09-00; online 2018-06-11]
Affiliated researcher
Autoantibody profiling reveals four protein candidate autoantigens associated with systemic lupus erythematosus.
Frostegård J, Hellström C, Nilsson P, Frostegård AG, Ajeganova S
Lupus 27 (10) 1670-1678 [2018-09-00; online 2018-07-24]
Affiliated researcher
A fine-needle aspiration-based protein signature discriminates benign from malignant breast lesions.
Franzén B, Kamali-Moghaddam M, Alexeyenko A, ..., Landegren U, Lewensohn R
Mol Oncol 12 (9) 1415-1428 [2018-09-00; online 2018-08-09]
Affiliated researcher
Top-Down Fabricated Silicon Nanowire Arrays for Field-Effect Detection of Prostate-Specific Antigen
Rani D, Pachauri V, Madaboosi N, ..., Conde JP, Ingebrandt S
ACS Omega 3 (8) 8471-8482 [2018-08-31; online 2018-08-00]
Affiliated researcher
Ca2+-binding protein NECAB2 facilitates inflammatory pain hypersensitivity.
Zhang MD, Su J, Adori C, ..., Harkany T, Hökfelt T
J. Clin. Invest. 128 (9) 3757-3768 [2018-08-31; online 2018-07-30]
Affiliated researcher
Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment.
Dyczynski M, Vesterlund M, Björklund AC, ..., Tamm KP, Nilsson R
Cell Death Dis 9 (9) 846 [2018-08-28; online 2018-08-28]
Affiliated researcher
A Protein-Based Encapsulation System with Calcium-Controlled Cargo Loading and Detachment.
Lizatović R, Assent M, Barendregt A, ..., Wennmalm S, André I
Angew. Chem. Int. Ed. Engl. 57 (35) 11334-11338 [2018-08-27; online 2018-07-30]
Affiliated researcher
Association of tamoxifen resistance and lipid reprogramming in breast cancer.
Hultsch S, Kankainen M, Paavolainen L, ..., Pietiäinen V, Kallioniemi O
BMC Cancer 18 (1) 850 [2018-08-24; online 2018-08-24]
Affiliated researcher
Stereotypic Immune System Development in Newborn Children.
Olin A, Henckel E, Chen Y, ..., Bohlin K, Brodin P
Cell 174 (5) 1277-1292.e14 [2018-08-23; online 2018-08-25]
Affiliated researcher
Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development.
Marques S, van Bruggen D, Vanichkina DP, ..., Taft RJ, Castelo-Branco G
Dev. Cell 46 (4) 504-517.e7 [2018-08-20; online 2018-08-02]
Affiliated researcher
Characterization of avian influenza virus attachment patterns to human and pig tissues.
Eriksson P, Lindskog C, Engholm E, ..., Jourdain E, Ellström P
Sci Rep 8 (1) 12215 [2018-08-15; online 2018-08-15]
Affiliated researcher
A Decomposition Method for Global Evaluation of Shannon Entropy and Local Estimations of Algorithmic Complexity
Zenil H, Hernández-Orozco S, Kiani N, ..., Rueda-Toicen A, Tegnér J
Entropy 20 (8) 605 [2018-08-15; online 2018-08-15]
Affiliated researcher
Predicting drug permeability through skin using molecular dynamics simulation.
Lundborg M, Wennberg CL, Narangifard A, Lindahl E, Norlén L
J Control Release 283 (-) 269-279 [2018-08-10; online 2018-06-01]
Affiliated researcher
Proteomic Biomarkers for Incident Aortic Stenosis Requiring Valvular Replacement.
Ljungberg J, Janiec M, Bergdahl IA, ..., Fall T, Söderberg S
Circulation 138 (6) 590-599 [2018-08-07; online 2018-03-01]
Affiliated researcher
Mitochondrial genomes reveal an east to west cline of steppe ancestry in Corded Ware populations.
Juras A, Chyleński M, Ehler E, ..., Jakobsson M, Kośko A
Sci Rep 8 (1) 11603 [2018-08-02; online 2018-08-02]
Affiliated researcher
Sulfonyl Fluorides (SFs): More Than Click Reagents?
Chinthakindi PK, Arvidsson PI
Eur. J. Org. Chem. 2018 (27-28) 3648-3666 [2018-08-01; online 2018-07-06]
Affiliated researcher
Different menopausal hormone regimens and risk of breast cancer.
Brusselaers N, Tamimi RM, Konings P, ..., Adami HO, Lagergren J
Ann. Oncol. 29 (8) 1771-1776 [2018-08-01; online 2018-06-20]
Affiliated researcher
The PDGF/PDGFR pathway as a drug target.
Papadopoulos N, Lennartsson J
Mol. Aspects Med. 62 (-) 75-88 [2018-08-00; online 2017-11-15]
Affiliated researcher
Structure and function of the global topsoil microbiome.
Bahram M, Hildebrand F, Forslund SK, ..., Tedersoo L, Bork P
Nature 560 (7717) 233-237 [2018-08-00; online 2018-08-01]
DDLS Fellow Johan Bengtsson-Palme
RNA velocity of single cells.
La Manno G, Soldatov R, Zeisel A, ..., Linnarsson S, Kharchenko PV
Nature 560 (7719) 494-498 [2018-08-00; online 2018-08-08]
Affiliated researcher
Plasma Protein Profiling Reveal Osteoprotegerin as a Marker of Prognostic Impact for Colorectal Cancer.
Birgisson H, Tsimogiannis K, Freyhult E, Kamali-Moghaddam M
Transl Oncol 11 (4) 1034-1043 [2018-08-00; online 2018-07-04]
Affiliated researcher
Modulation of TGFβ/Smad signaling by the small GTPase RhoB.
Livitsanou M, Vasilaki E, Stournaras C, Kardassis D
Cell. Signal. 48 (-) 54-63 [2018-08-00; online 2018-04-26]
Affiliated researcher
Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint.
Pieper J, Dubnovitsky A, Gerstner C, ..., Achour A, Malmström V
J. Autoimmun. 92 (-) 47-56 [2018-08-00; online 2018-05-28]
Affiliated researcher
Human skin barrier structure and function analyzed by cryo-EM and molecular dynamics simulation.
Lundborg M, Narangifard A, Wennberg CL, ..., Daneholt B, Norlén L
J. Struct. Biol. 203 (2) 149-161 [2018-08-00; online 2018-04-24]
Affiliated researcher
Ether cross-link formation in the R2-like ligand-binding oxidase.
Griese JJ, Branca RMM, Srinivas V, Högbom M
J. Biol. Inorg. Chem. 23 (6) 879-886 [2018-08-00; online 2018-06-26]
Affiliated researcher
Epigenetics in multiple myeloma: From mechanisms to therapy.
Alzrigat M, Párraga AA, Jernberg-Wiklund H
Semin. Cancer Biol. 51 (-) 101-115 [2018-08-00; online 2017-09-27]
Affiliated researcher
Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance.
Larsson DGJ, Andremont A, Bengtsson-Palme J, ..., Wellington EM, Wernersson AS
Environ Int 117 (-) 132-138 [2018-08-00; online 2018-05-07]
DDLS Fellow Johan Bengtsson-Palme
Consensus guidelines for the use and interpretation of angiogenesis assays.
Nowak-Sliwinska P, Alitalo K, Allen E, ..., Yoder MC, Griffioen AW
Angiogenesis 21 (3) 425-532 [2018-08-00; online 2018-05-17]
Affiliated researcher
Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis.
Kowalec K, Wright GEB, Drögemöller BI, ..., Tremlett H, Carleton BC
Nat. Genet. 50 (8) 1081-1085 [2018-08-00; online 2018-07-16]
Affiliated researcher
Characterization of Swedish Campylobacter coli clade 2 and clade 3 water isolates.
Nilsson A, Skarp A, Johansson C, ..., Engstrand L, Rautelin H
Microbiologyopen 7 (4) e00583 [2018-08-00; online 2018-02-09]
Affiliated researcher
Switch-like PKA responses in the nucleus of striatal neurons.
Yapo C, Nair AG, Hellgren Kotaleski J, Vincent P, Castro LRV
J. Cell. Sci. 131 (14) - [2018-07-27; online 2018-07-27]
Affiliated researcher
Whole genome SNP-associated signatures of local adaptation in honeybees of the Iberian Peninsula.
Henriques D, Wallberg A, Chávez-Galarza J, ..., Webster MT, Pinto MA
Sci Rep 8 (1) 11145 [2018-07-24; online 2018-07-24]
Affiliated researcher
Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome.
Sork H, Corso G, Krjutskov K, ..., Mäger I, El Andaloussi S
Sci Rep 8 (1) 10813 [2018-07-17; online 2018-07-17]
Affiliated researcher
Rapid Phenotypic Antibiotic Susceptibility Testing of Uropathogens Using Optical Signal Analysis on the Nanowell Slide.
Veses-Garcia M, Antypas H, Löffler S, ..., Andersson-Svahn H, Richter-Dahlfors A
Front Microbiol 9 (-) 1530 [2018-07-10; online 2018-07-10]
Affiliated researcher
Changes in brain architecture are consistent with altered fear processing in domestic rabbits.
Brusini I, Carneiro M, Wang C, ..., Fredrikson M, Andersson L
Proc. Natl. Acad. Sci. U.S.A. 115 (28) 7380-7385 [2018-07-10; online 2018-06-25]
Affiliated researcher
DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation.
Lemmens B, Hegarat N, Akopyan K, ..., Hochegger H, Lindqvist A
Mol. Cell 71 (1) 117-128.e3 [2018-07-05; online 2018-06-28]
Affiliated researcher
Morphological and genetic variation of Fucus in the eastern Gulf of Bothnia, northern Baltic Sea
Rinne H, Björkman U, Sjöqvist C, Salovius-Laurén S, Mattila J
European Journal of Phycology 53 (3) 369-380 [2018-07-03; online 2018-05-17]
Affiliated researcher
EviNet: a web platform for network enrichment analysis with flexible definition of gene sets.
Jeggari A, Alekseenko Z, Petrov I, ..., Ericson J, Alexeyenko A
Nucleic Acids Res. 46 (W1) W163-W170 [2018-07-02; online 2018-06-13]
Affiliated researcher
SETD2 Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma.
Sakthikumar S, Elvers I, Kim J, ..., Marinescu VD, Lindblad-Toh K
Cancer Res. 78 (13) 3421-3431 [2018-07-01; online 2018-05-03]
Affiliated researcher
Genome Evolution of Bartonellaceae Symbionts of Ants at the Opposite Ends of the Trophic Scale.
Bisch G, Neuvonen MM, Pierce NE, ..., Lukasik P, Andersson SGE
Genome Biol Evol 10 (7) 1687-1704 [2018-07-01; online 2018-07-10]
Affiliated researcher
A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate.
Riley AM, Unterlass J, Konieczny V, ..., Helleday T, Potter BVL
Med. Chem. Commun. 9 (7) 1105-1113 [2018-07-01; online 2018-06-04]
Affiliated researcher
Oak genome reveals facets of long lifespan.
Plomion C, Aury JM, Amselem J, ..., Kremer A, Salse J
Nat Plants 4 (7) 440-452 [2018-07-00; online 2018-06-18]
Affiliated researcher
Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis.
Leonard D, Svenungsson E, Dahlqvist J, ..., Criswell LA, Rönnblom L
Ann. Rheum. Dis. 77 (7) 1063-1069 [2018-07-00; online 2018-03-07]
Affiliated researcher
Molecular allergen profiling in horses by microarray reveals Fag e 2 from buckwheat as a frequent sensitizer.
Einhorn L, Hofstetter G, Brandt S, ..., Pali-Schöll I, Jensen-Jarolim E
Allergy 73 (7) 1436-1446 [2018-07-00; online 2018-02-27]
Affiliated researcher
Mining the Human Tissue Proteome for Protein Citrullination.
Lee CY, Wang D, Wilhelm M, ..., Hahne H, Kuster B
Mol. Cell Proteomics 17 (7) 1378-1391 [2018-07-00; online 2018-04-02]
Affiliated researcher
Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML.
Brück O, Blom S, Dufva O, ..., Pellinen T, Mustjoki S
Leukemia 32 (7) 1643-1656 [2018-07-00; online 2018-06-20]
Affiliated researcher
Identification of inhibitors of Tartrate-resistant acid phosphatase (TRAP/ACP5) activity by small-molecule screening.
Reithmeier A, Lundbäck T, Haraldsson M, ..., Gustavsson AL, Andersson G
Chem Biol Drug Des 92 (1) 1255-1271 [2018-07-00; online 2018-03-30]
Affiliated researcher
High speed of fork progression induces DNA replication stress and genomic instability.
Maya-Mendoza A, Moudry P, Merchut-Maya JM, ..., Strauss R, Bartek J
Nature 559 (7713) 279-284 [2018-07-00; online 2018-06-27]
Affiliated researcher
Genome-wide expression analysis suggests a role for jasmonates in the resistance to blue mold in apple
Ahmadi-Afzadi M, Orsel M, Pelletier S, ..., Nybom H, Renou JP
Plant Growth Regul 85 (3) 375-387 [2018-07-00; online 2018-04-18]
Affiliated researcher
Four evolutionary trajectories underlie genetic intratumoral variation in childhood cancer.
Karlsson J, Valind A, Holmquist Mengelbier L, ..., Bexell D, Gisselsson D
Nat. Genet. 50 (7) 944-950 [2018-07-00; online 2018-06-04]
Affiliated researcher
Demographic expansion and genetic load of the halophyte model plant Eutrema salsugineum.
Wang XJ, Hu QJ, Guo XY, ..., Lascoux M, Liu JQ
Mol. Ecol. 27 (14) 2943-2955 [2018-07-00; online 2018-06-22]
Affiliated researcher
Childhood Bereavement and Lower Stress Resilience in Late Adolescence.
Kennedy B, Chen R, Valdimarsdóttir U, ..., Fang F, Fall K
J Adolesc Health 63 (1) 108-114 [2018-07-00; online 2018-04-30]
Affiliated researcher
An in vitro model of lissencephaly: expanding the role of DCX during neurogenesis.
Shahsavani M, Pronk RJ, Falk R, ..., Gage FH, Falk A
Mol. Psychiatry 23 (7) 1674-1684 [2018-07-00; online 2017-09-19]
Affiliated researcher
In Vitro Evolution of Antibodies Inspired by In Vivo Evolution.
Persson H, Kirik U, Thörnqvist L, ..., Levander F, Ohlin M
Front Immunol 9 (-) 1391 [2018-06-21; online 2018-06-21]
Affiliated researcher
Gene expression profiling of periodontitis-affected gingival tissue by spatial transcriptomics.
Lundmark A, Gerasimcik N, Båge T, ..., Lundeberg J, Yucel-Lindberg T
Sci Rep 8 (1) 9370 [2018-06-19; online 2018-06-19]
Affiliated researcher
User-Friendly Genetic Conditional Knockout Strategies by CRISPR/Cas9.
Chen L, Ye Y, Dai H, ..., Ren W, Zhang W
Stem Cells Int 2018 (-) 9576959 [2018-06-14; online 2018-06-14]
Affiliated researcher
Investigating Holocene human population history in North Asia using ancient mitogenomes.
Kılınç GM, Kashuba N, Yaka R, ..., Storå J, Götherström A
Sci Rep 8 (1) 8969 [2018-06-12; online 2018-06-12]
Affiliated researcher
A universal platform for selection and high-resolution phenotypic screening of bacterial mutants using the nanowell slide.
Antypas H, Veses-Garcia M, Weibull E, Andersson-Svahn H, Richter-Dahlfors A
Lab Chip 18 (12) 1767-1777 [2018-06-12; online 2018-05-22]
Affiliated researcher
Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.
Gogola E, Duarte AA, de Ruiter JR, ..., Jonkers J, Rottenberg S
Cancer Cell 33 (6) 1078-1093.e12 [2018-06-11; online 2018-06-13]
Affiliated researcher
Whole Exome Sequencing of Patients from Multicase Families with Systemic Lupus Erythematosus Identifies Multiple Rare Variants.
Delgado-Vega AM, Martínez-Bueno M, Oparina NY, ..., Kozyrev SV, Alarcón-Riquelme ME
Sci Rep 8 (1) 8775 [2018-06-08; online 2018-06-08]
Affiliated researcher
Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance.
Nowak C, Hetty S, Salihovic S, ..., Fall T, Ingelsson E
Sci Rep 8 (1) 8691 [2018-06-06; online 2018-06-06]
Affiliated researcher
Mitochondrial Translation Efficiency Controls Cytoplasmic Protein Homeostasis.
Suhm T, Kaimal JM, Dawitz H, ..., Andréasson C, Ott M
Cell Metab. 27 (6) 1309-1322.e6 [2018-06-05; online 2018-05-10]
Affiliated researcher
Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids.
Treyer A, Mateus A, Wiśniewski JR, ..., Matsson P, Artursson P
Mol. Pharm. 15 (6) 2224-2233 [2018-06-04; online 2018-05-11]
Affiliated researcher
Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions.
Spiess M, Hernandez-Varas P, Oddone A, ..., Lakadamyali M, Strömblad S
J. Cell Biol. 217 (6) 1929-1940 [2018-06-04; online 2018-04-09]
Affiliated researcher
Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium.
Nicholson AM, Olpe C, Hoyle A, ..., Morrissey E, Winton DJ
Cell Stem Cell 22 (6) 909-918.e8 [2018-06-01; online 2018-05-17]
Affiliated researcher
A vertical flow paper-microarray assay with isothermal DNA amplification for detection of Neisseria meningitidis.
Rivas L, Reuterswärd P, Rasti R, ..., Gantelius J, Andersson-Svahn H
Talanta 183 (-) 192-200 [2018-06-01; online 2018-02-16]
Affiliated researcher
γ-glutamyl transpeptidase deficiency caused by a large homozygous intragenic deletion in GGT1.
Darin N, Leckström K, Sikora P, ..., Almén G, Asin-Cayuela J
Eur. J. Hum. Genet. 26 (6) 808-817 [2018-06-00; online 2018-02-26]
Affiliated researcher
Topology of membrane proteins-predictions, limitations and variations.
Tsirigos KD, Govindarajan S, Bassot C, ..., Shu N, Elofsson A
Curr. Opin. Struct. Biol. 50 (-) 9-17 [2018-06-00; online 2017-11-05]
Affiliated researcher
T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus.
Houtman M, Shchetynsky K, Chemin K, ..., Malmström V, Padyukov L
J. Autoimmun. 90 (-) 28-38 [2018-06-00; online 2018-02-03]
Affiliated researcher
Novel variants in Nordic patients referred for genetic testing of telomere-related disorders.
Norberg A, Rosén A, Raaschou-Jensen K, ..., Degerman S, Hultdin M
Eur. J. Hum. Genet. 26 (6) 858-867 [2018-06-00; online 2018-02-26]
Affiliated researcher
Improved protein model quality assessments by changing the target function.
Uziela K, Menéndez Hurtado D, Shu N, Wallner B, Elofsson A
Proteins 86 (6) 654-663 [2018-06-00; online 2018-04-15]
Affiliated researcher
Genomewide binding of transcription factor Snail1 in triple-negative breast cancer cells.
Maturi V, Morén A, Enroth S, Heldin CH, Moustakas A
Mol Oncol 12 (7) 1153-1174 [2018-06-00; online 2018-05-21]
Affiliated researcher
Thermophoresis-Controlled Size-Dependent DNA Translocation through an Array of Nanopores.
Zhang M, Ngampeerapong C, Redin D, ..., Sychugov I, Linnros J
ACS Nano 12 (5) 4574-4582 [2018-05-22; online 2018-04-19]
Affiliated researcher
Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery.
Simm J, Klambauer G, Arany A, ..., Moreau Y, Ceulemans H
Cell Chem Biol 25 (5) 611-618.e3 [2018-05-17; online 2018-03-01]
Affiliated researcher
Quantitation of Endogenous Metabolites in Mouse Tumors Using Mass-Spectrometry Imaging.
Swales JG, Dexter A, Hamm G, ..., Critchlow SE, Goodwin RJA
Anal. Chem. 90 (10) 6051-6058 [2018-05-15; online 2018-04-26]
Affiliated researcher
Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5.
Rossi Sebastiano M, Doak BC, Backlund M, ..., Matsson P, Kihlberg J
J. Med. Chem. 61 (9) 4189-4202 [2018-05-10; online 2018-04-16]
Affiliated researcher
Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology.
Liljeruhm J, Funk SK, Tietscher S, ..., Wistrand-Yuen E, Forster AC
J Biol Eng 12 (-) 8 [2018-05-10; online 2018-05-10]
Affiliated researcher
Response to "Comparison and Evaluation of Clustering Algorithms for Tandem Mass Spectra".
Griss J, Perez-Riverol Y, The M, Käll L, Vizcaíno JA
J. Proteome Res. 17 (5) 1993-1996 [2018-05-04; online 2018-04-25]
Affiliated researcher
A Protein Standard That Emulates Homology for the Characterization of Protein Inference Algorithms.
The M, Edfors F, Perez-Riverol Y, ..., Forsström B, Käll L
J. Proteome Res. 17 (5) 1879-1886 [2018-05-04; online 2018-04-16]
Affiliated researcher
Placental lncRNA Expression Is Associated With Prenatal Phthalate Exposure.
Machtinger R, Zhong J, Mansur A, ..., Karlsson O, Baccarelli AA
Toxicol Sci 163 (1) 116-122 [2018-05-01; online 2018-02-01]
Oskar Karlsson SciLifeLab Fellow
Overexpression of heparanase in mice promoted megakaryopoiesis.
Tan YX, Cui H, Wan LM, ..., Vlodavsky I, Li JP
Glycobiology 28 (5) 269-275 [2018-05-01; online 2018-02-23]
Affiliated researcher
Integrin α
Lidén Å, Karlsen TV, Guss B, Reed RK, Rubin K
Exp. Physiol. 103 (5) 629-634 [2018-05-01; online 2018-03-11]
Affiliated researcher
Estimating Age-Dependent Extinction: Contrasting Evidence from Fossils and Phylogenies.
Hagen O, Andermann T, Quental TB, Antonelli A, Silvestro D
Syst. Biol. 67 (3) 458-474 [2018-05-01; online 2017-10-27]
DDLS Fellow Tobias Andermann
Epoxide hydrolysis as a model system for understanding flux through a branched reaction scheme.
Janfalk Carlsson Å, Bauer P, Dobritzsch D, Kamerlin SCL, Widersten M
IUCrJ 5 (Pt 3) 269-282 [2018-05-01; online 2018-03-22]
Affiliated researcher
Snail regulates BMP and TGFβ pathways to control the differentiation status of glioma-initiating cells.
Caja L, Tzavlaki K, Dadras MS, ..., Heldin CH, Moustakas A
Oncogene 37 (19) 2515-2531 [2018-05-00; online 2018-02-16]
Affiliated researcher
Snail mediates crosstalk between TGFβ and LXRα in hepatocellular carcinoma.
Bellomo C, Caja L, Fabregat I, ..., Heldin CH, Moustakas A
Cell Death Differ. 25 (5) 885-903 [2018-05-00; online 2017-12-11]
Affiliated researcher
Prostaglandin E
Maric J, Ravindran A, Mazzurana L, ..., Konya V, Mjösberg J
J. Allergy Clin. Immunol. 141 (5) 1761-1773.e6 [2018-05-00; online 2017-12-05]
Affiliated researcher
Hyperglycemia Alters Expression of Cerebral Metabolic Genes after Cardiac Arrest.
Lindblom RPF, Molnar M, Israelsson C, ..., Wiklund L, Lennmyr F
J Stroke Cerebrovasc Dis 27 (5) 1200-1211 [2018-05-00; online 2018-01-03]
Affiliated researcher
ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation.
Malcikova J, Tausch E, Rossi D, ..., Pospisilova S, European Research Initiative on Chronic Lymphocytic Leukemia (ERIC) — TP53 network
Leukemia 32 (5) 1070-1080 [2018-05-00; online 2018-02-02]
Affiliated researcher
Detecting ligand interactions in real time on living bacterial cells.
Encarnação JC, Schulte T, Achour A, Björkelund H, Andersson K
Appl. Microbiol. Biotechnol. 102 (9) 4193-4201 [2018-05-00; online 2018-03-17]
Affiliated researcher
Deep mitochondrial origin outside the sampled alphaproteobacteria.
Martijn J, Vosseberg J, Guy L, Offre P, Ettema TJG
Nature 557 (7703) 101-105 [2018-05-00; online 2018-04-25]
Affiliated researcher
DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus.
Imgenberg-Kreuz J, Carlsson Almlöf J, Leonard D, ..., Syvänen AC, Sandling JK
Ann. Rheum. Dis. 77 (5) 736-743 [2018-05-00; online 2018-02-01]
Affiliated researcher
Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma.
Bolin S, Borgenvik A, Persson CU, ..., Weishaupt H, Swartling FJ
Oncogene 37 (21) 2850-2862 [2018-05-00; online 2018-03-07]
Affiliated researcher
Introducing ribosomal tandem repeat barcoding for fungi
Wurzbacher C, Larsson E, Bengtsson-Palme J, ..., Kagami M, Henrik Nilsson R
bioRxiv preprint - (-) - [2018-04-28; online 2018-04-28]
DDLS Fellow Johan Bengtsson-Palme
RNA-sequencing reveals long-term effects of silver nanoparticles on human lung cells.
Gliga AR, Di Bucchianico S, Lindvall J, Fadeel B, Karlsson HL
Sci Rep 8 (1) 6668 [2018-04-27; online 2018-04-27]
Affiliated researcher
TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer.
Caja L, Dituri F, Mancarella S, ..., Giannelli G, Fabregat I
Int J Mol Sci 19 (5) - [2018-04-26; online 2018-04-26]
Affiliated researcher
Rebooting Human Immunology.
Davis MM, Brodin P
Annu. Rev. Immunol. 36 (-) 843-864 [2018-04-26; online 2018-02-28]
Affiliated researcher
Experimental validation of predicted cancer genes using FRET.
Guala D, Bernhem K, Blal HA, ..., Brismar H, Sonnhammer ELL
Methods Appl Fluoresc 6 (3) 035007 [2018-04-25; online 2018-04-25]
Affiliated researcher
Repeated evolution of self-compatibility for reproductive assurance.
Nieuwenhuis BPS, Tusso S, Bjerling P, ..., Wolf JBW, Immler S
Nat Commun 9 (1) 1639 [2018-04-24; online 2018-04-24]
Affiliated researcher
Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.
Tikkanen E, Gustafsson S, Amar D, ..., Ashley EA, Ingelsson E
Sci Rep 8 (1) 6451 [2018-04-24; online 2018-04-24]
Affiliated researcher
Estimating genetic kin relationships in prehistoric populations.
Monroy Kuhn JM, Jakobsson M, Günther T
PLoS ONE 13 (4) e0195491 [2018-04-23; online 2018-04-23]
Affiliated researcher
Limited reverse transcriptase activity of phi29 DNA polymerase.
Krzywkowski T, Kühnemund M, Wu D, Nilsson M
Nucleic Acids Res. 46 (7) 3625-3632 [2018-04-20; online 2018-03-20]
Affiliated researcher
In Situ Target Engagement Studies in Adherent Cells.
Axelsson H, Almqvist H, Otrocka M, ..., Lundbäck T, Seashore-Ludlow B
ACS Chem. Biol. 13 (4) 942-950 [2018-04-20; online 2018-02-21]
Affiliated researcher
Microfluidic magnetic fluidized bed for DNA analysis in continuous flow mode.
Hernández-Neuta I, Pereiro I, Ahlford A, ..., Descroix S, Nilsson M
Biosens Bioelectron 102 (-) 531-539 [2018-04-15; online 2017-11-26]
Affiliated researcher
A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.
Berger AC, Korkut A, Kanchi RS, ..., Levine DA, Akbani R
Cancer Cell 33 (4) 690-705.e9 [2018-04-09; online 2018-04-02]
Affiliated researcher
Expression levels of long non-coding RNAs are prognostic for AML outcome.
Mer AS, Lindberg J, Nilsson C, ..., Lehmann S, Rantalainen M
J Hematol Oncol 11 (1) 52 [2018-04-07; online 2018-04-07]
Affiliated researcher
Modular assembly of the nucleolar pre-60S ribosomal subunit.
Sanghai ZA, Miller L, Molloy KR, ..., Chait BT, Klinge S
Nature 556 (7699) 126-129 [2018-04-05; online 2018-03-05]
Jonas Barandun SciLifeLab Fellow
Copy number of pancreatic polypeptide receptor gene NPY4R correlates with body mass index and waist circumference.
Shebanits K, Andersson-Assarsson JC, Larsson I, ..., Feuk L, Larhammar D
PLoS ONE 13 (4) e0194668 [2018-04-05; online 2018-04-05]
Affiliated researcher
LILRB1 polymorphisms influence posttransplant HCMV susceptibility and ligand interactions.
Yu K, Davidson CL, Wójtowicz A, ..., Swiss Transplant Cohort Study , Burshtyn DN
J. Clin. Invest. 128 (4) 1523-1537 [2018-04-02; online 2018-03-12]
Affiliated researcher
ERF deletion rescues RAS deficiency in mouse embryonic stem cells.
Mayor-Ruiz C, Olbrich T, Drosten M, ..., Ruiz S, Fernandez-Capetillo O
Genes Dev. 32 (7-8) 568-576 [2018-04-01; online 2018-04-12]
Affiliated researcher
Structural basis of ligand binding modes at the neuropeptide Y Y
Yang Z, Han S, Keller M, ..., Buschauer A, Wu B
Nature 556 (7702) 520-524 [2018-04-00; online 2018-04-18]
Affiliated researcher
Platelets, NETs and cancer.
Cedervall J, Hamidi A, Olsson AK
Thromb. Res. 164 Suppl 1 (-) S148-S152 [2018-04-00; online 2018-04-29]
Affiliated researcher
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Malik R, Chauhan G, Traylor M, ..., MEGASTROKE Consortium , MEGASTROKE Consortium:
Nat. Genet. 50 (4) 524-537 [2018-04-00; online 2018-03-12]
Affiliated researcher
Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT.
Abadpour S, Halvorsen B, Sahraoui A, ..., Aukrust P, Scholz H
J. Mol. Endocrinol. 60 (3) 171-183 [2018-04-00; online 2018-01-12]
Affiliated researcher
GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4
Bhandage AK, Jin Z, Korol SV, ..., Kamali-Moghaddam M, Birnir B
EBioMedicine 30 (-) 283-294 [2018-04-00; online 2018-03-28]
Affiliated researcher
EOMES-positive CD4
Chemin K, Ramsköld D, Diaz-Gallo LM, ..., Catrina A, Malmström V
Eur. J. Immunol. 48 (4) 655-669 [2018-04-00; online 2018-02-28]
Affiliated researcher
Confocal super-resolution imaging of the glomerular filtration barrier enabled by tissue expansion.
Unnersjö-Jess D, Scott L, Sevilla SZ, ..., Blom H, Brismar H
Kidney Int. 93 (4) 1008-1013 [2018-04-00; online 2017-12-11]
Affiliated researcher
Clinical relevance of integrin alpha 4 in gastrointestinal stromal tumours.
Pulkka OP, Mpindi JP, Tynninen O, ..., Sihto H, Joensuu H
J. Cell. Mol. Med. 22 (4) 2220-2230 [2018-04-00; online 2018-01-29]
Affiliated researcher
Biological/Genetic Regulation of Physical Activity Level: Consensus from GenBioPAC.
Lightfoot JT, DE Geus EJC, Booth FW, ..., Garland T, Bouchard C
Med Sci Sports Exerc 50 (4) 863-873 [2018-04-00; online 2017-11-23]
Affiliated researcher
Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes.
Klaesson A, Grannas K, Ebai T, ..., Söderberg O, Landegren U
Sci Rep 8 (1) 5400 [2018-03-29; online 2018-03-29]
Affiliated researcher
Computer simulations of the catalytic mechanism of wild-type and mutant β-phosphoglucomutase.
Barrozo A, Liao Q, Esguerra M, ..., Williams NH, Kamerlin SCL
Org. Biomol. Chem. 16 (12) 2060-2073 [2018-03-28; online 2018-03-06]
Affiliated researcher
AMYCNE: Confident copy number assessment using whole genome sequencing data.
Eisfeldt J, Nilsson D, Andersson-Assarsson JC, Lindstrand A
PLoS ONE 13 (3) e0189710 [2018-03-26; online 2018-03-26]
Affiliated researcher
Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury.
Dias DO, Kim H, Holl D, ..., Göritz C, Frisén J
Cell 173 (1) 153-165.e22 [2018-03-22; online 2018-03-01]
Affiliated researcher
Peptide ion channel toxins from the bootlace worm, the longest animal on Earth.
Jacobsson E, Andersson HS, Strand M, ..., Tytgat J, Göransson U
Sci Rep 8 (1) 4596 [2018-03-22; online 2018-03-22]
Affiliated researcher
Spironaphthoxazine switchable dyes for biological imaging.
Xiong Y, Vargas Jentzsch A, Osterrieth JWM, ..., Eggeling C, Anderson HL
Chem Sci 9 (11) 3029-3040 [2018-03-21; online 2018-02-20]
Erdinc Sezgin SciLifeLab Fellow
A Space Efficient Direct Access Data Compression Approach for Mass Spectrometry Imaging.
Källback P, Nilsson A, Shariatgorji M, Andrén PE
Anal. Chem. 90 (6) 3676-3682 [2018-03-20; online 2018-03-08]
Affiliated researcher
ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease.
Bremer HD, Landegren N, Sjöberg R, ..., Kämpe O, Hansson-Hamlin H
Sci Rep 8 (1) 4852 [2018-03-19; online 2018-03-19]
Affiliated researcher
Protein profiling in serum after traumatic brain injury in rats reveals potential injury markers.
Thelin EP, Just D, Frostell A, ..., Nilsson P, Bellander BM
Behav. Brain Res. 340 (-) 71-80 [2018-03-15; online 2016-08-31]
Affiliated researcher
Lipids Shape the Electron Acceptor-Binding Site of the Peripheral Membrane Protein Dihydroorotate Dehydrogenase.
Costeira-Paulo J, Gault J, Popova G, ..., Marklund EG, Landreh M
Cell Chem Biol 25 (3) 309-317.e4 [2018-03-15; online 2018-01-18]
Affiliated researcher
Wing bone geometry reveals active flight in Archaeopteryx.
Voeten DFAE, Cubo J, de Margerie E, ..., Tafforeau P, Sanchez S
Nat Commun 9 (1) 923 [2018-03-13; online 2018-03-13]
Affiliated researcher
Structural Transitions in Ceramide Cubic Phases during Formation of the Human Skin Barrier.
Wennberg CL, Narangifard A, Lundborg M, Norlén L, Lindahl E
Biophys. J. 114 (5) 1116-1127 [2018-03-13; online 2018-03-15]
Affiliated researcher
A comprehensive genomic history of extinct and living elephants.
Palkopoulou E, Lipson M, Mallick S, ..., Poinar H, Reich D
Proc. Natl. Acad. Sci. U.S.A. 115 (11) E2566-E2574 [2018-03-13; online 2018-02-26]
Affiliated researcher
Membrane protein serendipity.
von Heijne G
J. Biol. Chem. 293 (10) 3470-3476 [2018-03-09; online 2018-03-11]
Affiliated researcher
Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis.
Dias JT, Svedberg G, Nystrand M, Andersson-Svahn H, Gantelius J
J Vis Exp - (133) - [2018-03-07; online 2018-03-07]
Affiliated researcher
Sexual dimorphism in the width of the mouse synaptonemal complex.
Agostinho A, Kouznetsova A, Hernández-Hernández A, ..., Brismar H, Höög C
J. Cell. Sci. 131 (5) - [2018-03-06; online 2018-03-06]
Affiliated researcher
Characterization of the human RFX transcription factor family by regulatory and target gene analysis.
Sugiaman-Trapman D, Vitezic M, Jouhilahti EM, ..., Kere J, Swoboda P
BMC Genomics 19 (1) 181 [2018-03-06; online 2018-03-06]
Affiliated researcher
Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.
Azimi A, Caramuta S, Seashore-Ludlow B, ..., Uhlen M, Maddalo G
Mol Syst Biol 14 (3) e7858 [2018-03-05; online 2018-03-05]
Affiliated researcher
Synthesis of Galactosylated Glycosylphosphatidylinositol Derivatives from Trypanosoma brucei.
Grube M, Lee BY, Garg M, ..., Seeberger PH, Varón Silva D
Chemistry 24 (13) 3271-3282 [2018-03-02; online 2018-02-01]
Affiliated researcher
Perspective: APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution.
Venkatesan S, Rosenthal R, Kanu N, ..., Harris RS, Swanton C
Ann. Oncol. 29 (3) 563-572 [2018-03-01; online 2018-01-13]
Affiliated researcher
Impact of genetic risk loci for multiple sclerosis on expression of proximal genes in patients.
James T, Lindén M, Morikawa H, ..., Gomez-Cabrero D, Kockum I
Hum. Mol. Genet. 27 (5) 912-928 [2018-03-01; online 2018-01-13]
Affiliated researcher
Genetic variants influencing phenotypic variance heterogeneity.
Ek WE, Rask-Andersen M, Karlsson T, ..., Gyllensten U, Johansson Å
Hum. Mol. Genet. 27 (5) 799-810 [2018-03-01; online 2018-01-13]
Affiliated researcher
Slime mould: The fundamental mechanisms of biological cognition.
Vallverdú J, Castro O, Mayne R, ..., Zenil H, Adamatzky A
BioSystems 165 (-) 57-70 [2018-03-00; online 2018-01-08]
Affiliated researcher
Nubbin isoform antagonism governs Drosophila intestinal immune homeostasis.
Lindberg BG, Tang X, Dantoft W, ..., Lindvall JM, Engström Y
PLoS Pathog 14 (3) e1006936 [2018-03-00; online 2018-03-02]
Affiliated researcher
Methods for estimation of model accuracy in CASP12.
Elofsson A, Joo K, Keasar C, ..., Uziela K, Wallner B
Proteins 86 Suppl 1 (-) 361-373 [2018-03-00; online 2017-10-17]
Affiliated researcher
In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and
El-Heliebi A, Hille C, Laxman N, ..., Nilsson M, Sedlmayr P
Clin. Chem. 64 (3) 536-546 [2018-03-00; online 2018-01-04]
Affiliated researcher
Hypericin affects cancer side populations via competitive inhibition of BCRP.
Vargová J, Mikeš J, Jendželovský R, ..., Kozubík A, Fedoročko P
Biomed. Pharmacother. 99 (-) 511-522 [2018-03-00; online 2018-02-20]
Affiliated researcher
High methylmercury formation in ponds fueled by fresh humic and algal derived organic matter
Herrero Ortega S, Catalán N, Björn E, ..., Levanoni O, Bravo AG
Limnol. Oceanogr. 63 (S1) S44-S53 [2018-03-00; online 2017-11-10]
Affiliated researcher
First de novo whole genome sequencing and assembly of the pink-footed goose.
Pujolar JM, Dalén L, Olsen RA, Hansen MM, Madsen J
Genomics 110 (2) 75-79 [2018-03-00; online 2017-08-30]
Affiliated researcher
Femtosecond X-ray Fourier holography imaging of free-flying nanoparticles
Gorkhover T, Ulmer A, Ferguson K, ..., Hajdu J, Bostedt C
Nature Photon 12 (3) 150-153 [2018-03-00; online 2018-02-26]
Affiliated researcher
A genomic map of clinal variation across the European rabbit hybrid zone.
Rafati N, Blanco-Aguiar JA, Rubin CJ, ..., Andersson L, Carneiro M
Mol. Ecol. 27 (6) 1457-1478 [2018-03-00; online 2018-02-11]
Affiliated researcher
Current applications of antibody microarrays.
Chen Z, Dodig-Crnković T, Schwenk JM, Tao SC
Clin Proteomics 15 (-) 7 [2018-02-28; online 2018-02-28]
Affiliated researcher
Somatic mutagenesis in satellite cells associates with human skeletal muscle aging.
Franco I, Johansson A, Olsson K, ..., Fischer H, Eriksson M
Nat Commun 9 (1) 800 [2018-02-23; online 2018-02-23]
Affiliated researcher
Symbiosis in the microbial world: from ecology to genome evolution.
Raina JB, Eme L, Pollock FJ, ..., Archibald JM, Williams TA
Biol Open 7 (2) - [2018-02-22; online 2018-02-22]
Affiliated researcher
Interferometric scattering (iSCAT) microscopy: studies of biological membrane dynamics
Reina F, Galiani S, Shrestha D, ..., Eggeling C, Cole D
- - (-) - [2018-02-20; online 2018-02-20]
Erdinc Sezgin SciLifeLab Fellow
JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion.
Sundqvist A, Morikawa M, Ren J, ..., van Dam H, Ten Dijke P
Nucleic Acids Res. 46 (3) 1180-1195 [2018-02-16; online 2017-12-01]
Affiliated researcher
How many human proteoforms are there?
Aebersold R, Agar JN, Amster IJ, ..., Young NL, Zhang B
Nat. Chem. Biol. 14 (3) 206-214 [2018-02-14; online 2018-02-15]
Affiliated researcher
Advancing the immunoaffinity platform AFFIRM to targeted measurements of proteins in serum in the pg/ml range.
Säll A, Corbee D, Vikström S, ..., Persson H, Waldemarson S
PLoS ONE 13 (2) e0189116 [2018-02-13; online 2018-02-13]
Affiliated researcher
Efficient DNA-assisted synthesis of trans-membrane gold nanowires
Guo M, Hernández-Neuta I, Madaboosi N, Nilsson M, van der Wijngaart W
Microsyst. Nanoeng. 4 (-) 17084 [2018-02-12; online 2018-02-12]
Affiliated researcher
High prevalence of gait abnormalities in pugs.
Rohdin C, Jäderlund KH, Ljungvall I, Lindblad-Toh K, Häggström J
Vet. Rec. 182 (6) 167 [2018-02-10; online 2018-02-05]
Affiliated researcher
A flow-through nanoporous alumina trypsin bioreactor for mass spectrometry peptide fingerprinting.
Kjellander M, Billinger E, Ramachandraiah H, ..., Bergström Lind S, Johansson G
J Proteomics 172 (-) 165-172 [2018-02-10; online 2017-09-21]
Affiliated researcher
Evolution of neuropeptide signalling systems.
Elphick MR, Mirabeau O, Larhammar D
J. Exp. Biol. 221 (Pt 3) - [2018-02-09; online 2018-02-09]
Affiliated researcher
Particle Manipulation Methods in Droplet Microfluidics.
Tenje M, Fornell A, Ohlin M, Nilsson J
Anal. Chem. 90 (3) 1434-1443 [2018-02-06; online 2017-12-21]
Affiliated researcher
MonoRes: Automatic and Accurate Estimation of Local Resolution for Electron Microscopy Maps.
Vilas JL, Gómez-Blanco J, Conesa P, ..., Vargas J, Sorzano COS
Structure 26 (2) 337-344.e4 [2018-02-06; online 2018-01-27]
Affiliated researcher
MYCN-amplified neuroblastoma maintains an aggressive and undifferentiated phenotype by deregulation of estrogen and NGF signaling.
Dzieran J, Rodriguez Garcia A, Westermark UK, ..., Lehtiö J, Arsenian-Henriksson M
Proc. Natl. Acad. Sci. U.S.A. 115 (6) E1229-E1238 [2018-02-06; online 2018-01-26]
Affiliated researcher
Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation.
Agudelo LZ, Ferreira DMS, Cervenka I, ..., Berggren PO, Ruas JL
Cell Metab. 27 (2) 378-392.e5 [2018-02-06; online 2018-02-08]
Affiliated researcher
Human NUDT22 Is a UDP-Glucose/Galactose Hydrolase Exhibiting a Unique Structural Fold.
Carter M, Jemth AS, Carreras-Puigvert J, ..., Helleday T, Stenmark P
Structure 26 (2) 295-303.e6 [2018-02-06; online 2018-02-08]
Affiliated researcher
Phenotypic co-receptor tropism and Maraviroc sensitivity in HIV-1 subtype C from East Africa.
Siddik AB, Haas A, Rahman MS, ..., Klimkait T, Neogi U
Sci Rep 8 (1) 2363 [2018-02-05; online 2018-02-05]
Affiliated researcher
Binary particle separation in droplet microfluidics using acoustophoresis
Fornell A, Cushing K, Nilsson J, Tenje M
Appl. Phys. Lett. 112 (6) 063701 [2018-02-05; online 2018-02-05]
Affiliated researcher
Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin.
Teixeira PF, Masuyer G, Pinho CM, ..., Stenmark P, Glaser E
J. Mol. Biol. 430 (3) 348-362 [2018-02-02; online 2017-11-26]
Affiliated researcher
Synaptic markers of cognitive decline in neurodegenerative diseases: a proteomic approach.
Bereczki E, Branca RM, Francis PT, ..., Lehtiö J, Aarsland D
Brain 141 (2) 582-595 [2018-02-01; online 2018-01-13]
Affiliated researcher
Origin and Evolution of the Bartonella Gene Transfer Agent.
Tamarit D, Neuvonen MM, Engel P, Guy L, Andersson SGE
Mol. Biol. Evol. 35 (2) 451-464 [2018-02-01; online 2017-11-22]
Affiliated researcher
Formation of mercury methylation hotspots as a consequence of forestry operations.
Eklöf K, Bishop K, Bertilsson S, ..., Kronberg RM, Bravo AG
Sci. Total Environ. 613-614 (-) 1069-1078 [2018-02-01; online 2017-09-22]
Affiliated researcher
Targeted proteomic analysis of habitual coffee consumption.
Cornelis MC, Gustafsson S, Ärnlöv J, ..., Lind L, Ingelsson E
J. Intern. Med. 283 (2) 200-211 [2018-02-00; online 2017-11-16]
Affiliated researcher
Quantitative image analysis of protein expression and colocalisation in skin sections.
Zhang H, Ericsson M, Virtanen M, ..., Vahlquist A, Törmä H
Exp. Dermatol. 27 (2) 196-199 [2018-02-00; online 2018-01-09]
Affiliated researcher
Probing the activity of a recombinant Zn
Ravishankar H, Barth A, Andersson M
Biopolymers 109 (2) - [2018-02-00; online 2017-11-23]
Affiliated researcher
Comparative Action of Cardiotonic Steroids on Intracellular Processes in Rat Cortical Neurons.
Lopachev AV, Lopacheva OM, Nikiforova KA, ..., Fedorova TN, Akkuratov EE
Biochemistry Mosc. 83 (2) 140-151 [2018-02-00; online 2018-04-06]
Affiliated researcher
Asian horses deepen the MSY phylogeny.
Felkel S, Vogl C, Rigler D, ..., Brem G, Wallner B
Anim. Genet. 49 (1) 90-93 [2018-02-00; online 2018-01-15]
Affiliated researcher
A DNA methylation biomarker of alcohol consumption.
Liu C, Marioni RE, Hedman ÅK, ..., Ingelsson E, Levy D
Mol. Psychiatry 23 (2) 422-433 [2018-02-00; online 2016-11-15]
Affiliated researcher
Undecidability and Irreducibility Conditions for Open-Ended Evolution and Emergence.
Hernández-Orozco S, Hernández-Quiroz F, Zenil H
Artif. Life 24 (1) 56-70 [2018-01-25; online 2018-01-25]
Affiliated researcher
Metabolome dynamics of diapause in the butterfly
Lehmann P, Pruisscher P, Koštál V, ..., Wheat CW, Gotthard K
J. Exp. Biol. 221 (Pt 2) - [2018-01-25; online 2018-01-25]
Affiliated researcher
A caspase-2-RFXANK interaction and its implication for MHC class II expression.
Forsberg J, Li X, Akpinar B, ..., Zhivotovsky B, Olsson M
Cell Death Dis 9 (2) 80 [2018-01-23; online 2018-01-23]
Affiliated researcher
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.
Page BDG, Valerie NCK, Wright RHG, ..., Beato M, Helleday T
Nat Commun 9 (1) 250 [2018-01-17; online 2018-01-17]
Affiliated researcher
Intelligent image-based in situ single-cell isolation.
Brasko C, Smith K, Molnar C, ..., Tamas G, Horvath P
Nat Commun 9 (1) 226 [2018-01-15; online 2018-01-15]
Affiliated researcher
Citrullinated histone H3 as a novel prognostic blood marker in patients with advanced cancer.
Thålin C, Lundström S, Seignez C, ..., Wallén H, Demers M
PLoS ONE 13 (1) e0191231 [2018-01-11; online 2018-01-11]
Affiliated researcher
TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling.
Kawasaki N, Isogaya K, Dan S, ..., Miyazono K, Koinuma D
Cell Discov 4 (-) 1 [2018-01-09; online 2018-01-09]
Affiliated researcher
Polysome-profiling in small tissue samples.
Liang S, Bellato HM, Lorent J, ..., Hajj GNM, Larsson O
Nucleic Acids Res. 46 (1) e3 [2018-01-09; online 2017-10-27]
Affiliated researcher
Discovering viral genomes in human metagenomic data by predicting unknown protein families.
Barrientos-Somarribas M, Messina DN, Pou C, ..., Andersson B, Sonnhammer ELL
Sci Rep 8 (1) 28 [2018-01-08; online 2018-01-08]
Affiliated researcher
FunCoup 4: new species, data, and visualization.
Ogris C, Guala D, Sonnhammer ELL
Nucleic Acids Res. 46 (D1) D601-D607 [2018-01-04; online 2017-11-23]
Affiliated researcher
Elevated Proportions of Deleterious Genetic Variation in Domestic Animals and Plants.
Makino T, Rubin CJ, Carneiro M, ..., Andersson L, Webster MT
Genome Biol Evol 10 (1) 276-290 [2018-01-01; online 2018-01-13]
Affiliated researcher
Computational pan-genomics: status, promises and challenges.
Computational Pan-Genomics Consortium
Brief. Bioinformatics 19 (1) 118-135 [2018-01-01; online 2016-10-23]
Affiliated researcher
The association between p,p'-DDE levels and left ventricular mass is mainly mediated by obesity.
La Merrill MA, Lind PM, Salihovic S, van Bavel B, Lind L
Environ. Res. 160 (-) 541-546 [2018-01-00; online 2017-10-26]
Affiliated researcher
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Turcot V, Lu Y, Highland HM, ..., MAGIC Investigators , Understanding Society Scientific Group
Nat. Genet. 50 (1) 26-41 [2018-01-00; online 2017-12-22]
Affiliated researcher
Population genomics of Mesolithic Scandinavia: Investigating early postglacial migration routes and high-latitude adaptation.
Günther T, Malmström H, Svensson EM, ..., Götherström A, Jakobsson M
PLoS Biol. 16 (1) e2003703 [2018-01-00; online 2018-01-09]
Affiliated researcher
MicroRNA expression profiles in non‑epithelial ovarian tumors.
Chang RK, Li X, Mu N, ..., Larsson C, Lui WO
Int. J. Oncol. 52 (1) 55-66 [2018-01-00; online 2017-11-10]
Affiliated researcher
Genomic consequences of intensive inbreeding in an isolated wolf population.
Kardos M, Åkesson M, Fountain T, ..., Wikenros C, Ellegren H
Nat Ecol Evol 2 (1) 124-131 [2018-01-00; online 2017-11-20]
Affiliated researcher
Circulating proteins as predictors of incident heart failure in the elderly.
Stenemo M, Nowak C, Byberg L, ..., Fall T, Ärnlöv J
Eur. J. Heart Fail. 20 (1) 55-62 [2018-01-00; online 2017-10-02]
Affiliated researcher
An unexpected re-arrangement of the antibiotic carbapenem core to new 1,4-diazepin-5-one scaffolds
Peters BK, Razuwika R, Samipillai M, ..., Govender T, Naicker T
RSC Adv. 8 (1) 190-193 [2018-00-00; online 2018-00-00]
Affiliated researcher
Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery.
Peta V, Tse C, Perazzo H, ..., Drug Induced Liver Injury- Groupe Hospitalier Pitié-Salpêtrière , Drug Induced Liver Group of the Injury Safer and Faster Evidence-based Translation consortium
PLoS ONE 12 (12) e0189436 [2017-12-29; online 2017-12-29]
Affiliated researcher
Systematic exploration of multiple drug binding sites.
Bálint M, Jeszenői N, Horváth I, van der Spoel D, Hetényi C
J Cheminform 9 (1) 65 [2017-12-28; online 2017-12-28]
Affiliated researcher
Fluidic trapping and optical detection of microparticles with a functional optical fiber
Etcheverry S, Russom A, Laurell F, Margulis W
Opt Express 25 (26) 33657 [2017-12-25; online 2017-12-22]
Affiliated researcher
A common missense variant of LILRB5 is associated with statin intolerance and myalgia.
K Siddiqui M, Maroteau C, Veluchamy A, ..., Palmer CNA, PREDICTION-ADR Consortium
Eur. Heart J. 38 (48) 3569-3575 [2017-12-21; online 2017-10-12]
Affiliated researcher
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
Flannick J, Fuchsberger C, Mahajan A, ..., Boehnke M, McCarthy MI
Sci Data 4 (-) 170179 [2017-12-19; online 2017-12-19]
Affiliated researcher
On-chip conductometric detection of short DNA sequences via electro-hydrodynamic aggregation.
Venzac B, Diakité ML, Herthnek D, ..., Malaquin L, Viovy JL
Analyst 143 (1) 190-199 [2017-12-18; online 2017-11-25]
Affiliated researcher
A chemical screen identifies trifluoperazine as an inhibitor of glioblastoma growth.
Pinheiro T, Otrocka M, Seashore-Ludlow B, ..., Simon A, Kirkham M
Biochem. Biophys. Res. Commun. 494 (3-4) 477-483 [2017-12-16; online 2017-10-21]
Affiliated researcher
Detection of phasic dopamine by D1 and D2 striatal medium spiny neurons.
Yapo C, Nair AG, Clement L, ..., Hellgren Kotaleski J, Vincent P
J. Physiol. (Lond.) 595 (24) 7451-7475 [2017-12-15; online 2017-09-02]
Affiliated researcher
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.
Skrott Z, Mistrik M, Andersen KK, ..., Deshaies RJ, Bartek J
Nature 552 (7684) 194-199 [2017-12-14; online 2017-12-06]
Affiliated researcher
Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state.
Chen G, Abelein A, Nilsson HE, ..., Fisahn A, Johansson J
Nat Commun 8 (1) 2081 [2017-12-12; online 2017-12-12]
Affiliated researcher
6S RNA plays a role in recovery from nitrogen depletion in Synechocystis sp. PCC 6803.
Heilmann B, Hakkila K, Georg J, ..., Axmann IM, Dienst D
BMC Microbiol. 17 (1) 229 [2017-12-08; online 2017-12-08]
Affiliated researcher
Genomic and phenotypic characteristics of Swedish C. jejuni water isolates.
Nilsson A, Johansson C, Skarp A, ..., Engstrand L, Rautelin H
PLoS ONE 12 (12) e0189222 [2017-12-07; online 2017-12-07]
Affiliated researcher
A Unique ISR Program Determines Cellular Responses to Chronic Stress.
Guan BJ, van Hoef V, Jobava R, ..., Larsson O, Hatzoglou M
Mol. Cell 68 (5) 885-900.e6 [2017-12-07; online 2017-12-09]
Affiliated researcher
The Intriguing Evolutionary Journey of Enteroinvasive
Pasqua M, Michelacci V, Di Martino ML, ..., Morabito S, Prosseda G
Front Microbiol 8 (-) 2390 [2017-12-05; online 2017-12-05]
Affiliated researcher
The Human Cell Atlas.
Regev A, Teichmann SA, Lander ES, ..., Yosef N, Human Cell Atlas Meeting Participants
Elife 6 (-) - [2017-12-05; online 2017-12-05]
Affiliated researcher
A New Lineage of Eukaryotes Illuminates Early Mitochondrial Genome Reduction.
Janouškovec J, Tikhonenkov DV, Burki F, ..., Mylnikov AP, Keeling PJ
Curr. Biol. 27 (23) 3717-3724.e5 [2017-12-04; online 2017-11-22]
Affiliated researcher Fabien Burki SciLifeLab Fellow
Palladium(0)-Catalyzed Carbonylative One-Pot Synthesis of N-Acylguanidines.
Åkerbladh L, Schembri LS, Larhed M, Odell LR
J. Org. Chem. 82 (23) 12520-12529 [2017-12-01; online 2017-10-27]
Affiliated researcher
Trends in GPCR drug discovery: new agents, targets and indications.
Hauser AS, Attwood MM, Rask-Andersen M, Schiöth HB, Gloriam DE
Nat Rev Drug Discov 16 (12) 829-842 [2017-12-00; online 2017-10-27]
Affiliated researcher
PLS3 Deletions Lead to Severe Spinal Osteoporosis and Disturbed Bone Matrix Mineralization.
Kämpe AJ, Costantini A, Levy-Shraga Y, ..., Grasemann C, Mäkitie O
J. Bone Miner. Res. 32 (12) 2394-2404 [2017-12-00; online 2017-09-06]
Affiliated researcher
Loss of Conservation of Graph Centralities in Reverse-engineered Transcriptional Regulatory Networks
Weishaupt H, Johansson P, Engström C, ..., Silvestrov S, Swartling FJ
Methodol Comput Appl Probab 19 (4) 1089-1105 [2017-12-00; online 2017-04-03]
Affiliated researcher
Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent.
Mdanda S, Baijnath S, Shobo A, ..., Naicker T, Govender T
Biomed. Chromatogr. 31 (12) - [2017-12-00; online 2017-07-13]
Affiliated researcher
Inflammatory infiltrates in parathyroid tumors.
Haglund F, Hallström BM, Nilsson IL, ..., Juhlin CC, Larsson C
Eur. J. Endocrinol. 177 (6) 445-453 [2017-12-00; online 2017-08-30]
Affiliated researcher
East-West paths to unconventional computing.
Adamatzky A, Akl S, Burgin M, ..., Svozil K, Zenil H
Prog. Biophys. Mol. Biol. 131 (-) 469-493 [2017-12-00; online 2017-08-14]
Affiliated researcher
EPR Oximetry of Cetuximab-Treated Head-and-Neck Tumours in a Mouse Model.
Gustafsson H, Kale A, Dasu A, ..., Edqvist PH, Roberg K
Cell Biochem. Biophys. 75 (3-4) 299-309 [2017-12-00; online 2017-07-29]
Affiliated researcher
Cytotoxic T cells in chronic idiopathic neutropenia express restricted antigen receptors.
Mastrodemou S, Stalika E, Vardi A, ..., Papadaki HA, Stamatopoulos K
Leuk. Lymphoma 58 (12) 2926-2933 [2017-12-00; online 2017-05-23]
Affiliated researcher
Cancer as an ecomolecular disease and a neoplastic consortium.
Ramón Y Cajal S, Capdevila C, Hernandez-Losa J, ..., Postovit LM, Topisirovic I
Biochim Biophys Acta Rev Cancer 1868 (2) 484-499 [2017-12-00; online 2017-09-23]
Affiliated researcher
A female Viking warrior confirmed by genomics.
Hedenstierna-Jonson C, Kjellström A, Zachrisson T, ..., Götherström A, Storå J
Am. J. Phys. Anthropol. 164 (4) 853-860 [2017-12-00; online 2017-09-08]
Affiliated researcher
A short feature vector for image matching: The Log-Polar Magnitude feature descriptor.
Matuszewski DJ, Hast A, Wählby C, Sintorn IM
PLoS ONE 12 (11) e0188496 [2017-11-30; online 2017-11-30]
Affiliated researcher
STRT-seq-2i: dual-index 5' single cell and nucleus RNA-seq on an addressable microwell array.
Hochgerner H, Lönnerberg P, Hodge R, ..., Zeisel A, Linnarsson S
Sci Rep 7 (1) 16327 [2017-11-27; online 2017-11-27]
Affiliated researcher
Cohort-specific imputation of gene expression improves prediction of warfarin dose for African Americans.
Gottlieb A, Daneshjou R, DeGorter M, ..., Montgomery SB, Altman RB
Genome Med 9 (1) 98 [2017-11-24; online 2017-11-24]
Affiliated researcher
Determinism and Contingency Shape Metabolic Complementation in an Endosymbiotic Consortium.
Ponce-de-Leon M, Tamarit D, Calle-Espinosa J, ..., Montero F, Pereto J
Front Microbiol 8 (-) 2290 [2017-11-22; online 2017-11-22]
Affiliated researcher
Dog ownership and the risk of cardiovascular disease and death - a nationwide cohort study.
Mubanga M, Byberg L, Nowak C, ..., Ingelsson E, Fall T
Sci Rep 7 (1) 15821 [2017-11-17; online 2017-11-17]
Affiliated researcher
A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family.
Carreras-Puigvert J, Zitnik M, Jemth AS, ..., Zupan B, Helleday T
Nat Commun 8 (1) 1541 [2017-11-16; online 2017-11-16]
Affiliated researcher
Interleukin-33 Promotes Recruitment of Microglia/Macrophages in Response to Traumatic Brain Injury.
Wicher G, Wallenquist U, Lei Y, ..., Nilsson G, Forsberg-Nilsson K
J. Neurotrauma 34 (22) 3173-3182 [2017-11-15; online 2017-07-21]
Affiliated researcher
An exome sequencing based approach for genome-wide association studies in the dog.
Broeckx BJG, Derrien T, Mottier S, ..., Peelman L, Hitte C
Sci Rep 7 (1) 15680 [2017-11-15; online 2017-11-15]
Affiliated researcher
Systems pathology by multiplexed immunohistochemistry and whole-slide digital image analysis.
Blom S, Paavolainen L, Bychkov D, ..., Kallioniemi O, Pellinen T
Sci Rep 7 (1) 15580 [2017-11-14; online 2017-11-14]
Affiliated researcher
Human cytomegalovirus and Herpes Simplex type I virus can engage RNA polymerase I for transcription of immediate early genes.
Kostopoulou ON, Wilhelmi V, Raiss S, ..., Bartek J, Söderberg-Naucler C
Oncotarget 8 (57) 96536-96552 [2017-11-14; online 2017-10-29]
Affiliated researcher
Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.
Egaña I, Kaito H, Nitzsche A, ..., Hellström M, German Mouse Clinic Consortium
Sci Rep 7 (1) 15453 [2017-11-13; online 2017-11-13]
Affiliated researcher
Archaea and the origin of eukaryotes.
Eme L, Spang A, Lombard J, Stairs CW, Ettema TJG
Nat. Rev. Microbiol. 15 (12) 711-723 [2017-11-10; online 2017-11-11]
Affiliated researcher
Southern African ancient genomes estimate modern human divergence to 350,000 to 260,000 years ago.
Schlebusch CM, Malmström H, Günther T, ..., Lombard M, Jakobsson M
Science 358 (6363) 652-655 [2017-11-03; online 2017-09-28]
Affiliated researcher
Choline transporter mutations in severe congenital myasthenic syndrome disrupt transporter localization.
Wang H, Salter CG, Refai O, ..., Cirak S, Crosby AH
Brain 140 (11) 2838-2850 [2017-11-01; online 2017-11-01]
Affiliated researcher
The role of the skin microbiome in atopic dermatitis: a systematic review.
Bjerre RD, Bandier J, Skov L, Engstrand L, Johansen JD
Br. J. Dermatol. 177 (5) 1272-1278 [2017-11-00; online 2017-11-12]
Affiliated researcher
The complete structure of the small-subunit processome.
Barandun J, Chaker-Margot M, Hunziker M, ..., Chait BT, Klinge S
Nat. Struct. Mol. Biol. 24 (11) 944-953 [2017-11-00; online 2017-09-25]
Jonas Barandun SciLifeLab Fellow
SweGen: a whole-genome data resource of genetic variability in a cross-section of the Swedish population.
Ameur A, Dahlberg J, Olason P, ..., Magnusson PK, Gyllensten U
Eur. J. Hum. Genet. 25 (11) 1253-1260 [2017-11-00; online 2017-08-23]
Affiliated researcher
Species differences in pancreatic binding of DO3A-VS-Cys 40-Exendin4.
Eriksson O, Rosenström U, Selvaraju RK, Eriksson B, Velikyan I
Acta diabetologica 54 (11) 1039-1045 [2017-11-00; online 2017-09-11]
Olof Eriksson SciLifeLab Fellow
Medulloblastoma: experimental models and reality.
Neumann JE, Swartling FJ, Schüller U
Acta Neuropathol. 134 (5) 679-689 [2017-11-00; online 2017-07-19]
Affiliated researcher
Genetic landscape and deregulated pathways in B-cell lymphoid malignancies.
Rosenquist R, Beà S, Du MQ, Nadel B, Pan-Hammarström Q
J. Intern. Med. 282 (5) 371-394 [2017-11-00; online 2017-06-20]
Affiliated researcher
Enabling the synthesis of medium chain alkanes and 1-alkenes in yeast.
Zhu Z, Zhou YJ, Kang MK, ..., Buijs NA, Nielsen J
Metab. Eng. 44 (-) 81-88 [2017-11-00; online 2017-09-20]
Affiliated researcher
Early stages in the ontogeny of small B-cell lymphomas: genetics and microenvironment.
Ghia P, Nadel B, Sander B, Stamatopoulos K, Stevenson FK
J. Intern. Med. 282 (5) 395-414 [2017-11-00; online 2017-04-10]
Affiliated researcher
Comparison of
Opydo-Chanek M, Śladowska K, Blicharski K, ..., Niemeyer U, Mazur L
Anticancer Res. 37 (11) 6355-6361 [2017-11-00; online 2017-10-25]
Affiliated researcher
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
Scott RA, Scott LJ, Mägi R, ..., Prokopenko I, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Diabetes 66 (11) 2888-2902 [2017-11-00; online 2017-05-31]
Affiliated researcher
Thiol-ene-epoxy thermoset for low-temperature bonding to biofunctionalized microarray surfaces.
Zhou XC, Sjöberg R, Druet A, ..., Haraldsson T, Carlborg CF
Lab Chip 17 (21) 3672-3681 [2017-10-25; online 2017-10-05]
Affiliated researcher
Sex influences eQTL effects of SLE and Sjögren's syndrome-associated genetic polymorphisms.
Lindén M, Ramírez Sepúlveda JI, James T, ..., Kockum I, Wahren-Herlenius M
Biol Sex Differ 8 (1) 34 [2017-10-25; online 2017-10-25]
Affiliated researcher
Efficient protein production by yeast requires global tuning of metabolism.
Huang M, Bao J, Hallström BM, Petranovic D, Nielsen J
Nat Commun 8 (1) 1131 [2017-10-25; online 2017-10-25]
Affiliated researcher
Functional reconstruction of a eukaryotic-like E1/E2/(RING) E3 ubiquitylation cascade from an uncultured archaeon.
Hennell James R, Caceres EF, Escasinas A, ..., Ettema TJG, Robinson NP
Nat Commun 8 (1) 1120 [2017-10-24; online 2017-10-24]
Affiliated researcher
Development of a Bacterial Biosensor for Rapid Screening of Yeast p-Coumaric Acid Production.
Siedler S, Khatri NK, Zsohár A, ..., Sommer MOA, Joensson HN
ACS Synth. Biol. 6 (10) 1860-1869 [2017-10-20; online 2017-06-21]
Affiliated researcher
KIT signaling is dispensable for human mast cell progenitor development.
Dahlin JS, Ekoff M, Grootens J, ..., Olsson-Strömberg U, Nilsson G
Blood 130 (16) 1785-1794 [2017-10-19; online 2017-08-08]
Affiliated researcher
In situ genotyping of a pooled strain library after characterizing complex phenotypes.
Lawson MJ, Camsund D, Larsson J, ..., Fange D, Elf J
Mol Syst Biol 13 (10) 947 [2017-10-17; online 2017-10-17]
Affiliated researcher
Glioblastoma and glioblastoma stem cells are dependent on functional MTH1.
Pudelko L, Rouhi P, Sanjiv K, ..., Helleday T, Bräutigam L
Oncotarget 8 (49) 84671-84684 [2017-10-17; online 2017-07-20]
Affiliated researcher
Novel mutations in Darier disease and association to self-reported disease severity.
Leong IUS, Stuckey A, Ahanian T, Cederlöf M, Wikstrom JD
PLoS ONE 12 (10) e0186356 [2017-10-13; online 2017-10-13]
Affiliated researcher
Correlations in Scattered X-Ray Laser Pulses Reveal Nanoscale Structural Features of Viruses.
Kurta RP, Donatelli JJ, Yoon CH, ..., Zwart PH, Mancuso AP
Phys. Rev. Lett. 119 (15) 158102 [2017-10-13; online 2017-10-12]
Affiliated researcher
Synthesis of 11C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation.
Roslin S, Brandt P, Nordeman P, ..., Odell LR, Eriksson J
Molecules 22 (10) - [2017-10-10; online 2017-10-10]
Affiliated researcher
mTOR-sensitive translation: Cleared fog reveals more trees.
Masvidal L, Hulea L, Furic L, Topisirovic I, Larsson O
RNA Biol 14 (10) 1299-1305 [2017-10-03; online 2017-02-10]
Affiliated researcher
The Evolution of Dark Matter in the Mitogenome of Seed Beetles.
Sayadi A, Immonen E, Tellgren-Roth C, Arnqvist G
Genome Biol Evol 9 (10) 2697-2706 [2017-10-01; online 2017-10-20]
Affiliated researcher
Extensive Type II Muscle Fiber Atrophy in Elderly Female Hip Fracture Patients.
Kramer IF, Snijders T, Smeets JSJ, ..., Poeze M, van Loon LJC
J. Gerontol. A Biol. Sci. Med. Sci. 72 (10) 1369-1375 [2017-10-01; online 2017-03-23]
Affiliated researcher
Validation of risk stratification models in acute myeloid leukemia using sequencing-based molecular profiling.
Wang M, Lindberg J, Klevebring D, ..., Lehmann S, Grönberg H
Leukemia 31 (10) 2029-2036 [2017-10-00; online 2017-02-07]
Affiliated researcher
Synthesis of 4
Åkerbladh L, Chow SY, Odell LR, Larhed M
ChemistryOpen 6 (5) 620-628 [2017-10-00; online 2017-08-16]
Affiliated researcher
Reduced cell surface levels of GPI-linked markers in a new case with PIGG loss of function.
Zhao JJ, Halvardson J, Knaus A, ..., Thuresson AC, Feuk L
Hum. Mutat. 38 (10) 1394-1401 [2017-10-00; online 2017-06-12]
Affiliated researcher
PLS3 sequencing in childhood-onset primary osteoporosis identifies two novel disease-causing variants.
Kämpe AJ, Costantini A, Mäkitie RE, ..., Jiao H, Mäkitie O
Osteoporos Int 28 (10) 3023-3032 [2017-10-00; online 2017-07-26]
Affiliated researcher
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals.
Kraja AT, Cook JP, Warren HR, ..., Howson JMM, CHARGE EXOME BP, CHD Exome+, Exome BP, GoT2D:T2DGenes Consortia, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group†
Circ Cardiovasc Genet 10 (5) - [2017-10-00; online 2017-10-17]
Affiliated researcher
Menopausal hormone therapy and cancer risk: An overestimated risk?
Simin J, Tamimi R, Lagergren J, Adami HO, Brusselaers N
Eur. J. Cancer 84 (-) 60-68 [2017-10-00; online 2017-08-04]
Affiliated researcher
Maternal and female fetal testosterone levels are associated with maternal age and gestational weight gain.
Kallak TK, Hellgren C, Skalkidou A, ..., Campbell RE, Sundström Poromaa I
Eur. J. Endocrinol. 177 (4) 379-388 [2017-10-00; online 2017-07-13]
Erika Comasco SciLifeLab Fellow
H1N1 vaccination in Sjögren's syndrome triggers polyclonal B cell activation and promotes autoantibody production.
Brauner S, Folkersen L, Kvarnström M, ..., Nordmark G, Wahren-Herlenius M
Ann. Rheum. Dis. 76 (10) 1755-1763 [2017-10-00; online 2017-07-31]
Affiliated researcher
Dynamics and heterogeneity of brain damage in multiple sclerosis.
Kotelnikova E, Kiani NA, Abad E, ..., Garcia-Ojalvo J, Villoslada P
PLoS Comput Biol 13 (10) e1005757 [2017-10-00; online 2017-10-26]
Affiliated researcher
Breast cancer in young women and prognosis: How important are proliferation markers?
Fredholm H, Magnusson K, Lindström LS, ..., Frisell J, Fredriksson I
Eur. J. Cancer 84 (-) 278-289 [2017-10-00; online 2017-08-29]
Affiliated researcher
A drug pocket at the lipid bilayer-potassium channel interface.
Ottosson NE, Silverå Ejneby M, Wu X, ..., Lindahl E, Elinder F
Sci Adv 3 (10) e1701099 [2017-10-00; online 2017-10-25]
Affiliated researcher
Kinetics of dCas9 target search in
Jones DL, Leroy P, Unoson C, ..., Lawson MJ, Elf J
Science 357 (6358) 1420-1424 [2017-09-29; online 2017-09-28]
Affiliated researcher
Ecophysiology of Freshwater Verrucomicrobia Inferred from Metagenome-Assembled Genomes.
He S, Stevens SLR, Chan LK, ..., Malmstrom RR, McMahon KD
mSphere 2 (5) - [2017-09-27; online 2017-09-27]
Affiliated researcher
Autophagy is required for gamete differentiation in the moss Physcomitrella patens.
Sanchez-Vera V, Kenchappa CS, Landberg K, ..., Thelander M, Sundberg E
Autophagy 13 (11) 1939-1951 [2017-09-25; online 2017-09-25]
Affiliated researcher
Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins.
Bulanova D, Ianevski A, Bugai A, ..., Velagapudi V, Kainov DE
Viruses 9 (10) - [2017-09-25; online 2017-09-25]
Affiliated researcher
DESMAN: a new tool for de novo extraction of strains from metagenomes.
Quince C, Delmont TO, Raguideau S, ..., Collins G, Eren AM
Genome Biol. 18 (1) 181 [2017-09-21; online 2017-09-21]
Affiliated researcher
Polarity-Sensitive Probes for Superresolution Stimulated Emission Depletion Microscopy.
Sezgin E, Schneider F, Zilles V, ..., Klymchenko AS, Eggeling C
Biophys. J. 113 (6) 1321-1330 [2017-09-19; online 2017-07-19]
Erdinc Sezgin SciLifeLab Fellow
Tetrahydrobenzothiophene carboxamides: Beyond the kinase domain and into the fatty acid realm.
Llona-Minguez S, Fayezi S, Alihemmati A, ..., Piedrafita FJ, Helleday T
Bioorg. Med. Chem. Lett. 27 (18) 4462-4466 [2017-09-15; online 2017-08-05]
Affiliated researcher
Predicting accurate contacts in thousands of Pfam domain families using PconsC3.
Michel M, Skwark MJ, Menéndez Hurtado D, Ekeberg M, Elofsson A
Bioinformatics 33 (18) 2859-2866 [2017-09-15; online 2017-05-24]
Affiliated researcher
Heparin antagonizes cisplatin resistance of A2780 ovarian cancer cells by affecting the Wnt signaling pathway.
Pfankuchen DB, Baltes F, Batool T, ..., Schlesinger M, Bendas G
Oncotarget 8 (40) 67553-67566 [2017-09-15; online 2017-06-28]
Affiliated researcher
Mass Cytometry Identifies Distinct Lung CD4
Kaiser Y, Lakshmikanth T, Chen Y, ..., Achour A, Grunewald J
Front Immunol 8 (-) 1130 [2017-09-12; online 2017-09-12]
Affiliated researcher
Integrative taxonomy reveals too extensive lumping and a new species in the moss genus Amphidium (Bryophyta)
Sim-Sim M, Afonina OM, Almeida T, ..., González-Mancebo JM, Stech M
Systematics and Biodiversity 15 (5) 451-463 [2017-09-03; online 2017-01-19]
Affiliated researcher
Trap
Mayor-Ruiz C, Dominguez O, Fernandez-Capetillo O
J. Mol. Biol. 429 (18) 2780-2789 [2017-09-01; online 2017-08-04]
Affiliated researcher
The Huperzia selago Shoot Tip Transcriptome Sheds New Light on the Evolution of Leaves.
Evkaikina AI, Berke L, Romanova MA, ..., Pawlowski K, Voitsekhovskaja OV
Genome Biol Evol 9 (9) 2444-2460 [2017-09-01; online 2017-09-29]
Affiliated researcher
Reference Intervals for Fecal Calprotectin in Adults Using Two Different Extraction Methods in the Uppsala-SCAPIS Cohort.
Fall T, Mandic-Havelka A, Helmersson-Karlqvist J, Sundstrom J, Larsson A
Clin. Lab. 63 (9) 1493-1496 [2017-09-01; online 2017-09-08]
Affiliated researcher
Predicting allosteric mutants that increase activity of a major antibiotic resistance enzyme.
Latallo MJ, Cortina GA, Faham S, Nakamoto RK, Kasson PM
Chem Sci 8 (9) 6484-6492 [2017-09-01; online 2017-07-19]
Affiliated researcher
Multifocus structured illumination microscopy for fast volumetric super-resolution imaging.
Abrahamsson S, Blom H, Agostinho A, ..., Heintzmann R, Brismar H
Biomed Opt Express 8 (9) 4135-4140 [2017-09-01; online 2017-08-17]
Affiliated researcher
Genome-wide identification of Grainy head targets in
Yao L, Wang S, Westholm JO, ..., Lai EC, Samakovlis C
Development 144 (17) 3145-3155 [2017-09-01; online 2017-07-31]
Affiliated researcher
A practical guide to build
Montero-Mendieta S, Grabherr M, Lantz H, ..., Webster MT, Vilà C
PeerJ 5 (-) e3702 [2017-09-01; online 2017-09-01]
Affiliated researcher
Vascular sprouts induce local attraction of proangiogenic neutrophils.
Christoffersson G, Lomei J, O'Callaghan P, ..., Engblom S, Phillipson M
J Leukoc Biol 102 (3) 741-751 [2017-09-00; online 2017-06-05]
Gustaf Christoffersson SciLifeLab Fellow
The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases.
Ahsan M, Ek WE, Rask-Andersen M, ..., Gyllensten U, Johansson Å
PLoS Genet 13 (9) e1007005 [2017-09-00; online 2017-09-15]
Affiliated researcher
Peptide retention time prediction.
Moruz L, Käll L
Mass Spectrom Rev 36 (5) 615-623 [2017-09-00; online 2016-01-22]
Affiliated researcher
Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification.
Ebai T, Souza de Oliveira FM, Löf L, ..., Landegren U, Kamali-Moghaddam M
Clin. Chem. 63 (9) 1497-1505 [2017-09-00; online 2017-06-30]
Affiliated researcher
Gearing up to handle the mosaic nature of life in the quest for orthologs.
Forslund K, Pereira C, Capella-Gutierrez S, ..., Dessimoz C, Lewis S
Bioinformatics - (-) - [2017-08-30; online 2017-08-30]
Affiliated researcher
A p53-dependent response limits the viability of mammalian haploid cells.
Olbrich T, Mayor-Ruiz C, Vega-Sendino M, ..., Ruiz S, Fernandez-Capetillo O
Proc. Natl. Acad. Sci. U.S.A. 114 (35) 9367-9372 [2017-08-29; online 2017-08-14]
Affiliated researcher
Cerium oxide nanoparticles inhibit differentiation of neural stem cells.
Gliga AR, Edoff K, Caputo F, ..., Ceccatelli S, Fadeel B
Sci Rep 7 (1) 9284 [2017-08-24; online 2017-08-24]
Affiliated researcher
Clathrin-Independent Endocytosis Suppresses Cancer Cell Blebbing and Invasion.
Holst MR, Vidal-Quadras M, Larsson E, ..., Landström M, Lundmark R
Cell Reports 20 (8) 1893-1905 [2017-08-22; online 2017-08-24]
Affiliated researcher
PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway.
Reyhani V, Tsioumpekou M, van Wieringen T, ..., Lennartsson J, Rubin K
Sci Rep 7 (1) 8924 [2017-08-21; online 2017-08-21]
Affiliated researcher
Tea and coffee consumption in relation to DNA methylation in four European cohorts.
Ek WE, Tobi EW, Ahsan M, ..., Johansson Å, Epigenome-Wide Association Study Consortium
Hum. Mol. Genet. 26 (16) 3221-3231 [2017-08-15; online 2017-05-24]
Affiliated researcher
SubCons: a new ensemble method for improved human subcellular localization predictions.
Salvatore M, Warholm P, Shu N, Basile W, Elofsson A
Bioinformatics 33 (16) 2464-2470 [2017-08-15; online 2017-04-14]
Affiliated researcher
ST Pipeline: an automated pipeline for spatial mapping of unique transcripts.
Navarro JF, Sjöstrand J, Salmén F, Lundeberg J, Ståhl PL
Bioinformatics 33 (16) 2591-2593 [2017-08-15; online 2017-04-12]
Affiliated researcher
Automated Training of Deep Convolutional Neural Networks for Cell Segmentation.
Sadanandan SK, Ranefall P, Le Guyader S, Wählby C
Sci Rep 7 (1) 7860 [2017-08-10; online 2017-08-10]
Affiliated researcher
Long-term follow-up in primary Sjögren's syndrome reveals differences in clinical presentation between female and male patients.
Ramírez Sepúlveda JI, Kvarnström M, Eriksson P, ..., Nordmark G, Wahren-Herlenius M
Biol Sex Differ 8 (1) 25 [2017-08-08; online 2017-08-08]
Affiliated researcher
Use of Proteomics To Investigate Kidney Function Decline over 5 Years.
Carlsson AC, Ingelsson E, Sundström J, ..., Lind L, Ärnlöv J
Clin J Am Soc Nephrol 12 (8) 1226-1235 [2017-08-07; online 2017-07-21]
Affiliated researcher
Route to 3-Amidino Indoles via Pd(II)-Catalyzed C-H Bond Activation.
Rydfjord J, Skillinghaug B, Brandt P, Odell LR, Larhed M
Org. Lett. 19 (15) 4066-4069 [2017-08-04; online 2017-07-25]
Affiliated researcher
Enzyme Architecture: Modeling the Operation of a Hydrophobic Clamp in Catalysis by Triosephosphate Isomerase.
Kulkarni YS, Liao Q, Petrović D, ..., Richard JP, Kamerlin SCL
J. Am. Chem. Soc. 139 (30) 10514-10525 [2017-08-02; online 2017-07-19]
Affiliated researcher
Elsässer et al. reply.
Elsässer SJ, Noh KM, Diaz N, Allis CD, Banaszynski LA
Nature 548 (7665) E7-E9 [2017-08-02; online 2017-08-05]
SciLifeLab Fellow Simon Elsässer
Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease.
Mardinoglu A, Stančáková A, Lotta LA, ..., Langenberg C, Smith U
Cell Metab. 26 (2) 281-283 [2017-08-01; online 2017-08-03]
Adil Mardinoglu SciLifeLab Fellow
Gene Duplication Leads to Altered Membrane Topology of a Cytochrome P450 Enzyme in Seed Plants.
Renault H, De Marothy M, Jonasson G, ..., von Heijne G, Werck-Reichhart D
Mol. Biol. Evol. 34 (8) 2041-2056 [2017-08-01; online 2017-05-16]
Affiliated researcher
With me or against me: Tumor suppressor and drug resistance activities of SAMHD1.
Herold N, Rudd SG, Sanjiv K, ..., Henter JI, Schaller T
Exp. Hematol. 52 (-) 32-39 [2017-08-00; online 2017-05-11]
Affiliated researcher
Vimentin deficiency in macrophages induces CD36-mediated inflammation
Håversen L, Ståhlman M, Mattson Hultén L, ..., Levin M, Borén J
Atherosclerosis 263 (-) e87-e88 [2017-08-00; online 2017-08-00]
Adil Mardinoglu SciLifeLab Fellow
Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.
Deville C, Carroni M, Franke KB, ..., Mogk A, Saibil HR
Sci Adv 3 (8) e1701726 [2017-08-00; online 2017-08-04]
Affiliated researcher
Searching for Biosignatures in Exoplanetary Impact Ejecta.
Cataldi G, Brandeker A, Thébault P, ..., Neubeck A, Olofsson G
Astrobiology 17 (8) 721-746 [2017-08-00; online 2017-07-10]
Affiliated researcher
Replication stress, DNA damage signalling, and cytomegalovirus infection in human medulloblastomas.
Bartek J, Fornara O, Merchut-Maya JM, ..., Söderberg Naucler C, Bartkova J
Mol Oncol 11 (8) 945-964 [2017-08-00; online 2017-06-17]
Affiliated researcher
Objective automated quantification of fluorescence signal in histological sections of rat lens.
Talebizadeh N, Hagström NZ, Yu Z, ..., Söderberg P, Wählby C
Cytometry A 91 (8) 815-821 [2017-08-00; online 2017-05-11]
Affiliated researcher
Northeast African genomic variation shaped by the continuity of indigenous groups and Eurasian migrations.
Hollfelder N, Schlebusch CM, Günther T, ..., Hassan HY, Jakobsson M
PLoS Genet 13 (8) e1006976 [2017-08-00; online 2017-08-24]
Affiliated researcher
Multiple pathogen biomarker detection using an encoded bead array in droplet PCR.
Periyannan Rajeswari PK, Soderberg LM, Yacoub A, ..., Andersson Svahn H, Joensson HN
J. Microbiol. Methods 139 (-) 22-28 [2017-08-00; online 2017-04-20]
Affiliated researcher
Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and
Spyrou A, Kundu S, Haseeb L, ..., Vlodavsky I, Forsberg-Nilsson K
Mol. Cancer Ther. 16 (8) 1705-1716 [2017-08-00; online 2017-07-17]
Affiliated researcher
Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers.
Ward-Caviness CK, Xu T, Aspelund T, ..., Wang-Sattler R, Peters A
Heart 103 (16) 1278-1285 [2017-08-00; online 2017-03-02]
Affiliated researcher
Genotype-covariate interaction effects and the heritability of adult body mass index.
Robinson MR, English G, Moser G, ..., Cesarini D, Visscher PM
Nat. Genet. 49 (8) 1174-1181 [2017-08-00; online 2017-07-10]
Affiliated researcher
Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression.
Fedele V, Dai F, Masilamani AP, ..., Bredel M, Carro MS
Mol. Cancer Res. 15 (8) 998-1011 [2017-08-00; online 2017-05-16]
Affiliated researcher
Engineered Cpf1 variants with altered PAM specificities.
Gao L, Cox DBT, Yan WX, ..., Crosetto N, Zhang F
Nat. Biotechnol. 35 (8) 789-792 [2017-08-00; online 2017-06-05]
Affiliated researcher
Domestication rewired gene expression and nucleotide diversity patterns in tomato.
Sauvage C, Rau A, Aichholz C, ..., David J, Glémin S
Plant J. 91 (4) 631-645 [2017-08-00; online 2017-06-12]
Affiliated researcher
Childhood adiposity and risk of type 1 diabetes: A Mendelian randomization study.
Censin JC, Nowak C, Cooper N, ..., Todd JA, Fall T
PLoS Med. 14 (8) e1002362 [2017-08-00; online 2017-08-01]
Affiliated researcher
CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.
Gomez-Velazquez M, Badia-Careaga C, Lechuga-Vieco AV, ..., Gomez-Skarmeta JL, Manzanares M
PLoS Genet 13 (8) e1006985 [2017-08-00; online 2017-08-28]
Affiliated researcher
CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia.
Siddiqui MK, Veluchamy A, Maroteau C, ..., Palmer CNA, PREDICTION-ADR Consortium
Circ Cardiovasc Genet 10 (4) - [2017-08-00; online 2017-08-10]
Affiliated researcher
A
Dumanski JP, Rasi C, Björklund P, ..., Hellman P, Tiensuu Janson E
Endocr. Relat. Cancer 24 (8) 427-443 [2017-08-00; online 2017-06-20]
Affiliated researcher
Rapid signal enhancement method for nanoprobe-based biosensing.
Dias JT, Svedberg G, Nystrand M, Andersson-Svahn H, Gantelius J
Sci Rep 7 (1) 6837 [2017-07-28; online 2017-07-28]
Affiliated researcher
Vitamin D-deficient mice have more invasive urinary tract infection.
Hertting O, Lüthje P, Sullivan D, Aspenström P, Brauner A
PLoS ONE 12 (7) e0180810 [2017-07-27; online 2017-07-27]
Affiliated researcher
Droplet Barcode Sequencing for targeted linked-read haplotyping of single DNA molecules.
Redin D, Borgström E, He M, ..., Käller M, Ahmadian A
Nucleic Acids Res. 45 (13) e125 [2017-07-27; online 2017-05-20]
Affiliated researcher
Untargeted screening for novel autoantibodies with prognostic value in first-episode psychosis.
Zandian A, Wingård L, Nilsson H, ..., Nilsson P, Persson MAA
Transl Psychiatry 7 (7) e1177 [2017-07-25; online 2017-07-25]
Affiliated researcher
Continuous immunotypes describe human immune variation and predict diverse responses.
Kaczorowski KJ, Shekhar K, Nkulikiyimfura D, ..., Chakraborty AK, Brodin P
Proc. Natl. Acad. Sci. U.S.A. 114 (30) E6097-E6106 [2017-07-25; online 2017-07-10]
Affiliated researcher
Novel risk genes for systemic lupus erythematosus predicted by random forest classification.
Almlöf JC, Alexsson A, Imgenberg-Kreuz J, ..., Sandling JK, Syvänen AC
Sci Rep 7 (1) 6236 [2017-07-24; online 2017-07-24]
Affiliated researcher
Effects of Detergent Micelles on Lipid Binding to Proteins in Electrospray Ionization Mass Spectrometry.
Landreh M, Costeira-Paulo J, Gault J, Marklund EG, Robinson CV
Anal. Chem. 89 (14) 7425-7430 [2017-07-18; online 2017-07-03]
Affiliated researcher
De novo active sites for resurrected Precambrian enzymes.
Risso VA, Martinez-Rodriguez S, Candel AM, ..., Gavira JA, Sanchez-Ruiz JM
Nat Commun 8 (-) 16113 [2017-07-18; online 2017-07-18]
Affiliated researcher
Transancestral mapping and genetic load in systemic lupus erythematosus.
Langefeld CD, Ainsworth HC, Cunninghame Graham DS, ..., Gaffney PM, Vyse TJ
Nat Commun 8 (-) 16021 [2017-07-17; online 2017-07-17]
Affiliated researcher
High performance micro-flow cytometer based on optical fibres.
Etcheverry S, Faridi A, Ramachandraiah H, ..., Laurell F, Russom A
Sci Rep 7 (1) 5628 [2017-07-17; online 2017-07-17]
Affiliated researcher
Does antifouling paint select for antibiotic resistance?
Flach CF, Pal C, Svensson CJ, ..., Tysklind M, Larsson DGJ
Sci. Total Environ. 590-591 (-) 461-468 [2017-07-15; online 2017-03-08]
DDLS Fellow Johan Bengtsson-Palme
ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.
Jaiswal H, Benada J, Müllers E, ..., Macurek L, Lindqvist A
EMBO J. 36 (14) 2161-2176 [2017-07-14; online 2017-06-12]
Affiliated researcher
A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.
Malenczyk K, Girach F, Szodorai E, ..., Groop L, Harkany T
EMBO J. 36 (14) 2107-2125 [2017-07-14; online 2017-06-21]
Affiliated researcher
Y Chromosome Uncovers the Recent Oriental Origin of Modern Stallions.
Wallner B, Palmieri N, Vogl C, ..., Schlötterer C, Brem G
Curr. Biol. 27 (13) 2029-2035.e5 [2017-07-10; online 2017-06-29]
Affiliated researcher
Polyplex Evolution: Understanding Biology, Optimizing Performance.
Hall A, Lächelt U, Bartek J, Wagner E, Moghimi SM
Mol. Ther. 25 (7) 1476-1490 [2017-07-05; online 2017-03-06]
Affiliated researcher
Analysis of IAV Replication and Co-infection Dynamics by a Versatile RNA Viral Genome Labeling Method.
Dou D, Hernández-Neuta I, Wang H, ..., Nilsson M, Daniels R
Cell Reports 20 (1) 251-263 [2017-07-05; online 2017-07-07]
Affiliated researcher
SCENERY: a web application for (causal) network reconstruction from cytometry data.
Papoutsoglou G, Athineou G, Lagani V, ..., Tegnér J, Tsamardinos I
Nucleic Acids Res. 45 (W1) W270-W275 [2017-07-03; online 2017-05-20]
Affiliated researcher
Mineral Type Structures Soil Microbial Communities
Ahmed E, Hugerth LW, Logue JB, ..., Andersson AF, Holmström SJM
Geomicrobiology Journal 34 (6) 538-545 [2017-07-03; online 2016-11-22]
Affiliated researcher DDLS Fellow Luisa Hugerth
Structure-metabolism-relationships in the microsomal clearance of piperazin-1-ylpyridazines.
Llona-Minguez S, Ghassemian A, Baranczewski P, ..., Scobie M, Helleday T
Med. Chem. Commun. 8 (7) 1553-1560 [2017-07-01; online 2017-07-04]
Affiliated researcher
Dog Exposure During the First Year of Life and Type 1 Diabetes in Childhood.
Wernroth ML, Svennblad B, Fall K, ..., Almqvist C, Fall T
JAMA Pediatr 171 (7) 663-669 [2017-07-01; online 2017-05-02]
Affiliated researcher
Toward molecular imaging of the free fatty acid receptor 1.
Hellström-Lindahl E, Åberg O, Ericsson C, ..., Skrtic S, Eriksson O
Acta diabetologica 54 (7) 663-668 [2017-07-00; online 2017-04-13]
Olof Eriksson SciLifeLab Fellow
Stability of Proteins in Dried Blood Spot Biobanks.
Björkesten J, Enroth S, Shen Q, ..., Kamali-Moghaddam M, Landegren U
Mol. Cell Proteomics 16 (7) 1286-1296 [2017-07-00; online 2017-05-13]
Affiliated researcher
Numerous Ontogenetic Roads to Mantle Cell Lymphoma: Immunogenetic and Immunohistochemical Evidence.
Pouliou E, Xochelli A, Kanellis G, ..., Stamatopoulos K, Papadaki T
Am. J. Pathol. 187 (7) 1454-1458 [2017-07-00; online 2017-04-28]
Affiliated researcher
Low-algorithmic-complexity entropy-deceiving graphs.
Zenil H, Kiani NA, Tegnér J
Phys Rev E 96 (1-1) 012308 [2017-07-00; online 2017-07-07]
Affiliated researcher
Genomewide analysis of admixture and adaptation in the Africanized honeybee.
Nelson RM, Wallberg A, Simões ZLP, Lawson DJ, Webster MT
Mol. Ecol. 26 (14) 3603-3617 [2017-07-00; online 2017-04-24]
Affiliated researcher
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.
Young E, Noerenberg D, Mansouri L, ..., Rosenquist R, Damm F
Leukemia 31 (7) 1547-1554 [2017-07-00; online 2016-11-28]
Affiliated researcher
Detection of 6-demethoxyubiquinone in CoQ
Herebian D, Seibt A, Smits SHJ, ..., Mayatepek E, Distelmaier F
Mol. Genet. Metab. 121 (3) 216-223 [2017-07-00; online 2017-05-20]
Affiliated researcher
Autoimmune polyendocrine syndrome type 1 in an Indian cohort: a longitudinal study.
Zaidi G, Bhatia V, Sahoo SK, ..., Agarwal S, Bhatia E
Endocr Connect 6 (5) 289-296 [2017-07-00; online 2017-04-26]
Affiliated researcher
A longitudinal assessment of miR-122 and GLDH as biomarkers of drug-induced liver injury in the rat.
Thulin P, Hornby RJ, Auli M, ..., Glinghammar B, Schuppe-Koistinen I
Biomarkers 22 (5) 461-469 [2017-07-00; online 2016-12-15]
Affiliated researcher
A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation.
Beloqui A, Brayden DJ, Artursson P, Préat V, des Rieux A
Nat Protoc 12 (7) 1387-1399 [2017-07-00; online 2017-06-15]
Affiliated researcher
A Low-Frequency Inactivating
Manning A, Highland HM, Gasser J, ..., Gloyn AL, Lindgren CM
Diabetes 66 (7) 2019-2032 [2017-07-00; online 2017-03-24]
Affiliated researcher
Moderate nucleotide diversity in the Atlantic herring is associated with a low mutation rate.
Feng C, Pettersson M, Lamichhaney S, ..., Folkvord A, Andersson L
Elife 6 (-) - [2017-06-30; online 2017-06-30]
Affiliated researcher
Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC.
Strell C, Norberg KJ, Mezheyeuski A, ..., Johansen JS, Östman A
Br. J. Cancer 117 (1) 65-77 [2017-06-27; online 2017-05-18]
Affiliated researcher
Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice.
Martikainen M, Ruotsalainen J, Tuomela J, ..., Heikkilä J, Hinkkanen A
Br. J. Cancer 117 (1) 51-55 [2017-06-27; online 2017-05-30]
Affiliated researcher
GeneSPIDER - gene regulatory network inference benchmarking with controlled network and data properties.
Tjärnberg A, Morgan DC, Studham M, Nordling TEM, Sonnhammer ELL
Mol Biosyst 13 (7) 1304-1312 [2017-06-27; online 2017-05-10]
Affiliated researcher
Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source.
Reddy HKN, Yoon CH, Aquila A, ..., Williams GJ, Xavier PL
Sci Data 4 (-) 170079 [2017-06-27; online 2017-06-27]
Affiliated researcher
Identification of novel small molecules that inhibit STAT3-dependent transcription and function.
Kolosenko I, Yu Y, Busker S, ..., Page BDG, Grander D
PLoS ONE 12 (6) e0178844 [2017-06-21; online 2017-06-21]
Affiliated researcher
Global Kinetic Mechanism of Microsomal Glutathione Transferase 1 and Insights into Dynamic Enzyme Activation.
Spahiu L, Ålander J, Ottosson-Wadlund A, ..., Armstrong RN, Morgenstern R
Biochemistry 56 (24) 3089-3098 [2017-06-20; online 2017-06-09]
Affiliated researcher
Synthetic approaches to radiochemical probes for imaging of bacterial infections.
Dutta J, Naicker T, Ebenhan T, ..., Arvidsson PI, Govender T
Eur J Med Chem 133 (-) 287-308 [2017-06-16; online 2017-03-29]
Affiliated researcher
Insufficient antibody validation challenges oestrogen receptor beta research.
Andersson S, Sundberg M, Pristovsek N, ..., Williams C, Asplund A
Nat Commun 8 (-) 15840 [2017-06-15; online 2017-06-15]
Affiliated researcher
Identification of the adenovirus type 2 C-168 protein.
Gromova A, Zhao H, Konzer A, ..., Pettersson U, Lind SB
Virus Res. 238 (-) 110-113 [2017-06-15; online 2017-06-16]
Affiliated researcher
Stimulated Emission Depletion Microscopy.
Blom H, Widengren J
Chem. Rev. 117 (11) 7377-7427 [2017-06-14; online 2017-03-06]
Affiliated researcher
Genetic loci associated with heart rate variability and their effects on cardiac disease risk.
Nolte IM, Munoz ML, Tragante V, ..., Snieder H, de Geus EJC
Nat Commun 8 (-) 15805 [2017-06-14; online 2017-06-14]
Affiliated researcher
Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost.
Bornelöv S, Seroussi E, Yosefi S, ..., Friedman-Einat M, Andersson L
Genome Biol. 18 (1) 112 [2017-06-14; online 2017-06-14]
Affiliated researcher
Loss of Cardioprotective Effects at the
Saleheen D, Zhao W, Young R, ..., Samani NJ, Reilly MP
Circulation 135 (24) 2336-2353 [2017-06-13; online 2017-05-01]
Affiliated researcher
Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo).
Maret-Ouda J, Wahlin K, Artama M, ..., Euler-Chelpin MV, Lagergren J
BMJ Open 7 (6) e016505 [2017-06-08; online 2017-06-08]
Affiliated researcher
SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts.
Stattin EL, Henning P, Klar J, ..., Wikström J, Lerner UH
Sci Rep 7 (1) 3012 [2017-06-07; online 2017-06-07]
Affiliated researcher
Integrative modeling of gene and genome evolution roots the archaeal tree of life.
Williams TA, Szöllősi GJ, Spang A, ..., Ettema TJG, Embley TM
Proc. Natl. Acad. Sci. U.S.A. 114 (23) E4602-E4611 [2017-06-06; online 2017-05-22]
Affiliated researcher
SAMHD1 protects cancer cells from various nucleoside-based antimetabolites.
Herold N, Rudd SG, Sanjiv K, ..., Henter JI, Schaller T
Cell Cycle 16 (11) 1029-1038 [2017-06-03; online 2017-04-24]
Affiliated researcher
Simultaneous Single-Cell
Krzywkowski T, Ciftci S, Assadian F, Nilsson M, Punga T
J. Virol. 91 (11) - [2017-06-01; online 2017-05-12]
Affiliated researcher
Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.
Aschard H, Tobin MD, Hancock DB, ..., London SJ, Kraft P
Int J Epidemiol 46 (3) 894-904 [2017-06-01; online 2017-01-14]
Affiliated researcher
Role of interferons in SLE.
Bengtsson AA, Rönnblom L
Best Pract Res Clin Rheumatol 31 (3) 415-428 [2017-06-00; online 2017-11-03]
Affiliated researcher
Results of a collaborative study on DNA identification of aged bone samples
Vanek D, Budowle B, Dubska-Votrubova J, ..., Vella J, Zander J
Croat Med J 58 (3) 203-213 [2017-06-00; online 2017-06-00]
Affiliated researcher
Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking.
Doucet M, Becker KF, Björkman J, ..., Zatloukal K, Dagher G
Biopreserv Biobank 15 (3) 270-276 [2017-06-00; online 2016-12-19]
Affiliated researcher
Multirate method for co-simulation of electrical-chemical systems in multiscale modeling.
Brocke E, Djurfeldt M, Bhalla US, Kotaleski JH, Hanke M
J Comput Neurosci 42 (3) 245-256 [2017-06-00; online 2017-04-07]
Affiliated researcher
MicroBubble activated acoustic cell sorting.
Faridi MA, Ramachandraiah H, Iranmanesh I, ..., Wiklund M, Russom A
Biomed Microdevices 19 (2) 23 [2017-06-00; online 2017-04-05]
Affiliated researcher
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.
Christophersen IE, Rienstra M, Roselli C, ..., Ellinor PT, AFGen Consortium
Nat. Genet. 49 (6) 946-952 [2017-06-00; online 2017-04-17]
Affiliated researcher
LASSIM-A network inference toolbox for genome-wide mechanistic modeling.
Magnusson R, Mariotti GP, Köpsén M, ..., Tjärnberg A, Gustafsson M
PLoS Comput Biol 13 (6) e1005608 [2017-06-00; online 2017-06-22]
Affiliated researcher
Global survey of the immunomodulatory potential of common drugs.
Vladimer GI, Snijder B, Krall N, ..., Jäger U, Superti-Furga G
Nat. Chem. Biol. 13 (6) 681-690 [2017-06-00; online 2017-04-24]
Affiliated researcher
Genome sequencing and population genomic analyses provide insights into the adaptive landscape of silver birch.
Salojärvi J, Smolander OP, Nieminen K, ..., Helariutta Y, Kangasjärvi J
Nat. Genet. 49 (6) 904-912 [2017-06-00; online 2017-05-08]
Affiliated researcher
Fast and general tests of genetic interaction for genome-wide association studies.
Frånberg M, Strawbridge RJ, Hamsten A, ..., Lagergren J, Sennblad B
PLoS Comput Biol 13 (6) e1005556 [2017-06-00; online 2017-06-06]
Affiliated researcher
Effects of beaver impoundments on dissolved organic matter quality and biodegradability in boreal riverine systems
Catalán N, Herrero Ortega S, Gröntoft H, ..., Bishop K, Bravo AG
Hydrobiologia 793 (1) 135-148 [2017-06-00; online 2016-05-23]
Affiliated researcher
Association analysis of KIT, MITF, and PAX3 variants with white markings in Spanish horses.
Negro S, Imsland F, Valera M, ..., Solé M, Andersson L
Anim. Genet. 48 (3) 349-352 [2017-06-00; online 2017-01-13]
Affiliated researcher
High-affinity recognition of the human C-reactive protein independent of phosphocholine.
Yang J, Gustavsson AL, Haraldsson M, ..., Norberg T, Baltzer L
Org. Biomol. Chem. 15 (21) 4644-4654 [2017-05-31; online 2017-05-18]
Affiliated researcher
Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2).
Pedersen JM, Khan EK, Bergström CAS, ..., Hoogstraate J, Artursson P
Eur J Pharm Sci 103 (-) 70-76 [2017-05-30; online 2017-03-02]
Affiliated researcher
Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes.
Väremo L, Henriksen TI, Scheele C, ..., Pedersen BK, Nielsen J
Genome Med 9 (1) 47 [2017-05-25; online 2017-05-25]
Affiliated researcher
Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors.
Llona-Minguez S, Höglund A, Ghassemian A, ..., Scobie M, Helleday T
J. Med. Chem. 60 (10) 4279-4292 [2017-05-25; online 2017-05-16]
Affiliated researcher
RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases.
Battaglia S, Lidschreiber M, Baejen C, ..., Vos SM, Cramer P
Elife 6 (-) - [2017-05-24; online 2017-05-24]
Affiliated researcher
Selective Synthesis of Spirooxindoles by an Intramolecular Heck-Mizoroki Reaction.
Roy T, Brandt P, Wetzel A, ..., Sävmarker J, Larhed M
Org. Lett. 19 (10) 2738-2741 [2017-05-19; online 2017-05-04]
Affiliated researcher
AT
Bernhem K, Krishnan K, Bondar A, ..., Aperia A, Scott L
BMC Cardiovasc Disord 17 (1) 126 [2017-05-17; online 2017-05-17]
Affiliated researcher
ProQ3D: improved model quality assessments using deep learning.
Uziela K, Menéndez Hurtado D, Shu N, Wallner B, Elofsson A
Bioinformatics 33 (10) 1578-1580 [2017-05-15; online 2017-01-06]
Affiliated researcher
GWAR: robust analysis and meta-analysis of genome-wide association studies.
Dimou NL, Tsirigos KD, Elofsson A, Bagos PG
Bioinformatics 33 (10) 1521-1527 [2017-05-15; online 2017-01-22]
Affiliated researcher
Expression proteomics study to determine metallodrug targets and optimal drug combinations.
Lee RFS, Chernobrovkin A, Rutishauser D, ..., Zubarev RA, Dyson PJ
Sci Rep 7 (1) 1590 [2017-05-08; online 2017-05-08]
Affiliated researcher
EndoC-βH1 cells display increased sensitivity to sodium palmitate when cultured in DMEM/F12 medium.
Krizhanovskii C, Kristinsson H, Elksnis A, ..., Scharfmann R, Welsh N
Islets 9 (3) e1296995 [2017-05-04; online 2017-02-28]
Affiliated researcher
Experimental strategies for imaging bioparticles with femtosecond hard X-ray pulses.
Daurer BJ, Okamoto K, Bielecki J, ..., Hajdu J, Larsson DSD
IUCrJ 4 (Pt 3) 251-262 [2017-05-01; online 2017-04-07]
Affiliated researcher
[ 11C]5-hydroxy-tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes.
Carlbom L, Espes D, Lubberink M, ..., Korsgren O, Eriksson O
Diabetes 66 (5) 1286-1292 [2017-05-00; online 2017-02-28]
Olof Eriksson SciLifeLab Fellow
Transcriptomics and methylomics of CD4-positive T cells in arsenic-exposed women.
Engström K, Wojdacz TK, Marabita F, ..., Vahter M, Broberg K
Arch. Toxicol. 91 (5) 2067-2078 [2017-05-00; online 2016-11-12]
Affiliated researcher
Time to onset of bisphosphonate-related osteonecrosis of the jaws: a multicentre retrospective cohort study.
Fung P, Bedogni G, Bedogni A, ..., GENVABO Consortium , Fedele S
Oral Dis 23 (4) 477-483 [2017-05-00; online 2017-03-06]
Affiliated researcher
Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR.
Borgatti A, Koopmeiners JS, Sarver AL, ..., Modiano JF, Vallera DA
Mol. Cancer Ther. 16 (5) 956-965 [2017-05-00; online 2017-02-13]
Affiliated researcher
Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study.
Bränn E, Papadopoulos F, Fransson E, ..., Sundström-Poromaa I, Skalkidou A
Psychoneuroendocrinology 79 (-) 146-159 [2017-05-00; online 2017-02-28]
Affiliated researcher
Evolutionary forces affecting synonymous variations in plant genomes.
Clément Y, Sarah G, Holtz Y, ..., David J, Glémin S
PLoS Genet 13 (5) e1006799 [2017-05-00; online 2017-05-22]
Affiliated researcher
Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML.
Malani D, Murumägi A, Yadav B, ..., Aittokallio T, Kallioniemi O
Leukemia 31 (5) 1187-1195 [2017-05-00; online 2016-11-11]
Affiliated researcher
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.
Gorski M, van der Most PJ, Teumer A, ..., Böger CA, Fuchsberger C
Sci Rep 7 (-) 45040 [2017-04-28; online 2017-04-28]
Affiliated researcher
Persistent Effects of Developmental Exposure to 17α-Ethinylestradiol on the Zebrafish (
Porseryd T, Volkova K, Reyhanian Caspillo N, ..., Dinnetz P, Porsh Hällström I
Front Behav Neurosci 11 (-) 69 [2017-04-20; online 2017-04-20]
Affiliated researcher
Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage.
Kaucka M, Zikmund T, Tesarova M, ..., Fried K, Adameyko I
Elife 6 (-) - [2017-04-17; online 2017-04-17]
Affiliated researcher
Improved orthology inference with Hieranoid 2.
Kaduk M, Sonnhammer E
Bioinformatics 33 (8) 1154-1159 [2017-04-15; online 2017-01-18]
Affiliated researcher
Adaptation to infectious disease exposure in indigenous Southern African populations.
Owers KA, Sjödin P, Schlebusch CM, ..., Soodyall H, Jakobsson M
Proc. Biol. Sci. 284 (1852) - [2017-04-12; online 2017-04-07]
Affiliated researcher
Direct evidence for a polygenic etiology in familial multiple myeloma.
Halvarsson BM, Wihlborg AK, Ali M, ..., Hansson M, Nilsson B
Blood Adv 1 (10) 619-623 [2017-04-11; online 2017-04-07]
Abhishek Niroula DDLS Fellow
Genome-wide Analysis of RNA Polymerase II Termination at Protein-Coding Genes.
Baejen C, Andreani J, Torkler P, ..., Söding J, Cramer P
Mol. Cell 66 (1) 38-49.e6 [2017-04-06; online 2017-03-16]
Affiliated researcher
Quantum dots modulate intracellular Ca
Yin H, Fontana JM, Solandt J, ..., Brismar H, Fu Y
Int J Nanomedicine 12 (-) 2781-2792 [2017-04-05; online 2017-04-05]
Affiliated researcher
dUTPase inhibition augments replication defects of 5-Fluorouracil.
Hagenkort A, Paulin CBJ, Desroses M, ..., Scobie M, Helleday T
Oncotarget 8 (14) 23713-23726 [2017-04-04; online 2017-04-21]
Affiliated researcher
Optimizing Analytical Depth and Cost Efficiency of IEF-LC/MS Proteomics.
Kifer I, Branca RM, Ben-Dor A, ..., Lehtio J, Yakhini Z
IEEE/ACM Trans Comput Biol Bioinform 14 (2) 272-281 [2017-04-04; online 2017-04-04]
Affiliated researcher
Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia.
Löf L, Arngården L, Olsson-Strömberg U, ..., Landegren U, Kamali-Moghaddam M
Sci Rep 7 (1) 623 [2017-04-04; online 2017-04-04]
Affiliated researcher
Sulfonimidamides in Medicinal and Agricultural Chemistry.
Chinthakindi PK, Naicker T, Thota N, ..., Kruger HG, Arvidsson PI
Angew. Chem. Int. Ed. Engl. 56 (15) 4100-4109 [2017-04-03; online 2017-02-23]
Affiliated researcher
Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer.
Mathot L, Kundu S, Ljungström V, ..., Nilsson M, Sjöblom T
Cancer Res. 77 (7) 1730-1740 [2017-04-01; online 2017-01-20]
Affiliated researcher
Menopausal hormone therapy and the risk of esophageal and gastric cancer.
Brusselaers N, Maret-Ouda J, Konings P, El-Serag HB, Lagergren J
Int. J. Cancer 140 (7) 1693-1699 [2017-04-01; online 2017-01-06]
Affiliated researcher
Discrimination of pancreatic cancer and pancreatitis by LC-MS metabolomics.
Lindahl A, Heuchel R, Forshed J, ..., Löhr M, Nordström A
Metabolomics 13 (5) 61 [2017-04-01; online 2017-04-01]
Affiliated researcher
The evolution of Sex-linked barring alleles in chickens involves both regulatory and coding changes in CDKN2A.
Schwochow Thalmann D, Ring H, Sundström E, ..., Tixier-Boichard M, Andersson L
PLoS Genet 13 (4) e1006665 [2017-04-00; online 2017-04-07]
Affiliated researcher
Sensitive magnetic biodetection using magnetic multi-core nanoparticles and RCA coils
Ahrentorp F, Blomgren J, Jonasson C, ..., Strømme M, Johansson C
Journal of Magnetism and Magnetic Materials 427 (-) 14-18 [2017-04-00; online 2017-04-00]
Affiliated researcher
Prediction and Prevention of Parasitic Diseases Using a Landscape Genomics Framework.
Schwabl P, Llewellyn MS, Landguth EL, ..., Ocaña S, Grijalva MJ
Trends Parasitol. 33 (4) 264-275 [2017-04-00; online 2016-11-16]
Affiliated researcher
Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.
Folkersen L, Fauman E, Sabater-Lleal M, ..., Hamsten A, Mälarstig A
PLoS Genet 13 (4) e1006706 [2017-04-00; online 2017-04-03]
Affiliated researcher
Human behavioral complexity peaks at age 25.
Gauvrit N, Zenil H, Soler-Toscano F, Delahaye JP, Brugger P
PLoS Comput Biol 13 (4) e1005408 [2017-04-00; online 2017-04-13]
Affiliated researcher
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
Graff M, Scott RA, Justice AE, ..., Loos RJF, Kilpeläinen TO
PLoS Genet 13 (4) e1006528 [2017-04-00; online 2017-04-27]
Affiliated researcher
Frequent low-level mutations of protein kinase D2 in angiolipoma.
Hofvander J, Arbajian E, Stenkula KG, ..., Hornick JL, Mertens F
J. Pathol. 241 (5) 578-582 [2017-04-00; online 2017-02-27]
Affiliated researcher
FZD
Hot B, Valnohova J, Arthofer E, ..., Mulder J, Schulte G
Cell. Signal. 32 (-) 93-103 [2017-04-00; online 2017-01-24]
Affiliated researcher
Expanding the product portfolio of fungal type I fatty acid synthases.
Zhu Z, Zhou YJ, Krivoruchko A, ..., Zhao ZK, Nielsen J
Nat. Chem. Biol. 13 (4) 360-362 [2017-04-00; online 2017-02-20]
Affiliated researcher
Epigenome-wide DNA methylation study of IgE concentration in relation to self-reported allergies.
Ek WE, Ahsan M, Rask-Andersen M, ..., Gyllensten U, Johansson Å
Epigenomics 9 (4) 407-418 [2017-04-00; online 2017-03-21]
Affiliated researcher
Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.
Nicoletti P, Aithal GP, Bjornsson ES, ..., Daly AK, International Drug-Induced Liver Injury Consortium, Drug-Induced Liver Injury Network Investigators, and International Serious Adverse Events Consortium
Gastroenterology 152 (5) 1078-1089 [2017-04-00; online 2016-12-30]
Affiliated researcher
Analysis of FOXP3
Schmidt A, Rieger CC, Venigalla RK, ..., Krammer PH, Kuhn A
Immunol. Res. 65 (2) 551-563 [2017-04-00; online 2017-02-23]
Affiliated researcher
Electroformation of Giant Unilamellar Vesicles on Stainless Steel Electrodes.
Pereno V, Carugo D, Bau L, ..., Eggeling C, Stride E
ACS Omega 2 (3) 994-1002 [2017-03-31; online 2017-03-16]
Erdinc Sezgin SciLifeLab Fellow
Improvement of identification methods for honeybee specific Lactic Acid Bacteria; future approaches.
Lamei S, Hu YO, Olofsson TC, ..., Forsgren E, Vásquez A
PLoS ONE 12 (3) e0174614 [2017-03-27; online 2017-03-27]
Affiliated researcher
Modeling and Targeting MYC Genes in Childhood Brain Tumors.
Hutter S, Bolin S, Weishaupt H, Swartling FJ
Genes (Basel) 8 (4) - [2017-03-23; online 2017-03-23]
Affiliated researcher
Helicobacter pylori eradication in the Swedish population.
Doorakkers E, Lagergren J, Gajulapuri VK, ..., Engstrand L, Brusselaers N
Scand. J. Gastroenterol. 52 (6-7) 678-685 [2017-03-21; online 2017-03-21]
Affiliated researcher
Electrochemical Genetic Profiling of Single Cancer Cells.
Acero Sánchez JL, Joda H, Henry OY, ..., Latta D, O'Sullivan CK
Anal. Chem. 89 (6) 3378-3385 [2017-03-21; online 2017-02-28]
Affiliated researcher
Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.
Blondiaux N, Moune M, Desroses M, ..., Willand N, Baulard AR
Science 355 (6330) 1206-1211 [2017-03-17; online 2017-03-16]
Affiliated researcher
PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c.
Pan G, Ameur A, Enroth S, ..., Gyllensten U, Wadelius C
Nucleic Acids Res. 45 (5) 2408-2422 [2017-03-17; online 2016-12-10]
Affiliated researcher
Total biosynthesis of the cyclic AMP booster forskolin from
Pateraki I, Andersen-Ranberg J, Jensen NB, ..., Møller BL, Hamberger B
Elife 6 (-) - [2017-03-14; online 2017-03-14]
Affiliated researcher
Microbial community assembly and evolution in subseafloor sediment.
Starnawski P, Bataillon T, Ettema TJ, ..., Schramm A, Kjeldsen KU
Proc. Natl. Acad. Sci. U.S.A. 114 (11) 2940-2945 [2017-03-14; online 2017-02-27]
Affiliated researcher
Immunogenicity is preferentially induced in sparse dendritic cell cultures.
Nasi A, Bollampalli VP, Sun M, ..., Rothfuchs AG, Réthi B
Sci Rep 7 (-) 43989 [2017-03-09; online 2017-03-09]
Affiliated researcher
Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.
Llona-Minguez S, Höglund A, Wiita E, ..., Scobie M, Helleday T
J. Med. Chem. 60 (5) 2148-2154 [2017-03-09; online 2017-02-15]
Affiliated researcher
Discovery of circulating proteins associated to knee radiographic osteoarthritis.
Lourido L, Ayoglu B, Fernández-Tajes J, ..., Nilsson P, Blanco FJ
Sci Rep 7 (1) 137 [2017-03-09; online 2017-03-09]
Affiliated researcher
Whole-Proteome Peptide Microarrays for Profiling Autoantibody Repertoires within Multiple Sclerosis and Narcolepsy.
Zandian A, Forsström B, Häggmark-Månberg A, ..., Nilsson P, Ayoglu B
J. Proteome Res. 16 (3) 1300-1314 [2017-03-03; online 2017-02-09]
Affiliated researcher
A hybrid method for the imputation of genomic data in livestock populations.
Antolín R, Nettelblad C, Gorjanc G, Money D, Hickey JM
Genet. Sel. Evol. 49 (1) 30 [2017-03-03; online 2017-03-03]
Affiliated researcher
Gentle, fast and effective crystal soaking by acoustic dispensing.
Collins PM, Ng JT, Talon R, ..., Pearce NM, von Delft F
Acta Crystallogr D Struct Biol 73 (Pt 3) 246-255 [2017-03-01; online 2017-03-06]
DDLS Fellow Nicholas Pearce
Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.
Ma R, Karthik GM, Lövrot J, ..., Fredriksson I, Hartman J
J. Natl. Cancer Inst. 109 (3) 1-14 [2017-03-01; online 2017-04-05]
Affiliated researcher
Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays.
Larssen P, Wik L, Czarnewski P, ..., Gabrielsson S, Kamali-Moghaddam M
Mol. Cell Proteomics 16 (3) 502-511 [2017-03-00; online 2017-01-22]
Affiliated researcher
The use of a Swedish telephone medical advice service by the elderly - a population-based study.
Dahlgren K, Holzmann MJ, Carlsson AC, ..., Hasselström J, Ruge T
Scand J Prim Health Care 35 (1) 98-104 [2017-03-00; online 2017-03-03]
Affiliated researcher
Phylogenetic analysis of
Barbosa RN, Leong SL, Vinnere-Pettersson O, ..., Oliveira NT, Houbraken J
Stud. Mycol. 86 (-) 29-51 [2017-03-00; online 2017-04-12]
Affiliated researcher
Overexpression of heparanase attenuated TGF-β-stimulated signaling in tumor cells.
Batool T, Fang J, Barash U, ..., Vlodavsky I, Li JP
FEBS Open Bio 7 (3) 405-413 [2017-03-00; online 2017-02-11]
Affiliated researcher
Human ROBO1 regulates white matter structure in corpus callosum.
Darki F, Massinen S, Salmela E, ..., Klingberg T, Kere J
Brain Struct Funct 222 (2) 707-716 [2017-03-00; online 2016-05-30]
Affiliated researcher
High GC content causes orphan proteins to be intrinsically disordered.
Basile W, Sachenkova O, Light S, Elofsson A
PLoS Comput Biol 13 (3) e1005375 [2017-03-00; online 2017-03-29]
Affiliated researcher
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.
Warren HR, Evangelou E, Cabrera CP, ..., International Genomics of Blood Pressure (iGEN-BP) Consortium , UK Biobank CardioMetabolic Consortium BP working group
Nat. Genet. 49 (3) 403-415 [2017-03-00; online 2017-01-30]
Affiliated researcher
Development of [
Stepanov V, Svedberg M, Jia Z, ..., Nordberg A, Halldin C
Nucl. Med. Biol. 46 (-) 50-53 [2017-03-00; online 2016-12-09]
Affiliated researcher
Cotranslational folding of spectrin domains via partially structured states.
Nilsson OB, Nickson AA, Hollins JJ, ..., von Heijne G, Clarke J
Nat. Struct. Mol. Biol. 24 (3) 221-225 [2017-03-00; online 2017-01-23]
Affiliated researcher
Biomimetic spinning of artificial spider silk from a chimeric minispidroin.
Andersson M, Jia Q, Abella A, ..., Johansson J, Rising A
Nat. Chem. Biol. 13 (3) 262-264 [2017-03-00; online 2017-01-09]
Affiliated researcher
Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis ‬.
Zeitelhofer M, Adzemovic MZ, Gomez-Cabrero D, ..., Guerreiro-Cacais AO, Jagodic M
Proc. Natl. Acad. Sci. U.S.A. 114 (9) E1678-E1687 [2017-02-28; online 2017-02-14]
Affiliated researcher
Intracellular drug bioavailability: a new predictor of system dependent drug disposition.
Mateus A, Treyer A, Wegler C, ..., Matsson P, Artursson P
Sci Rep 7 (-) 43047 [2017-02-22; online 2017-02-22]
Affiliated researcher
Comparison of whole genome amplification techniques for human single cell exome sequencing.
Borgström E, Paterlini M, Mold JE, Frisen J, Lundeberg J
PLoS ONE 12 (2) e0171566 [2017-02-16; online 2017-02-16]
Affiliated researcher
Nitration of MOG diminishes its encephalitogenicity depending on MHC haplotype.
Warnecke A, Musunuri S, N'diaye M, ..., Bergquist J, Harris RA
J. Neuroimmunol. 303 (-) 1-12 [2017-02-15; online 2016-11-26]
Affiliated researcher
Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor.
Gustafsson R, Jemth AS, Gustafsson NM, ..., Helleday T, Stenmark P
Cancer Res. 77 (4) 937-948 [2017-02-15; online 2016-11-29]
Affiliated researcher
The Baltic Sea Virome: Diversity and Transcriptional Activity of DNA and RNA Viruses.
Zeigler Allen L, McCrow JP, Ininbergs K, ..., Bergman B, Venter JC
mSystems 2 (1) - [2017-02-14; online 2017-02-14]
Affiliated researcher
A novel RNA sequencing data analysis method for cell line authentication.
Fasterius E, Raso C, Kennedy S, ..., Uhlén M, Al-Khalili Szigyarto C
PLoS ONE 12 (2) e0171435 [2017-02-13; online 2017-02-13]
Affiliated researcher
Genetic and Functional Study of L-Type Amino Acid Transporter 1 in Schizophrenia.
Comasco E, Vumma R, Toffoletto S, ..., Jönsson EG, Venizelos N
Neuropsychobiology 74 (2) 96-103 [2017-02-11; online 2017-02-11]
Erika Comasco SciLifeLab Fellow
Nanometer resolution imaging and tracking of fluorescent molecules with minimal photon fluxes.
Balzarotti F, Eilers Y, Gwosch KC, ..., Elf J, Hell SW
Science 355 (6325) 606-612 [2017-02-10; online 2016-12-22]
Affiliated researcher
Rare and low-frequency coding variants alter human adult height.
Marouli E, Graff M, Medina-Gomez C, ..., Deloukas P, Lettre G
Nature 542 (7640) 186-190 [2017-02-09; online 2017-02-01]
Affiliated researcher
Molecular composition of organic matter controls methylmercury formation in boreal lakes.
Bravo AG, Bouchet S, Tolu J, ..., Mateos-Rivera A, Bertilsson S
Nat Commun 8 (-) 14255 [2017-02-09; online 2017-02-09]
Affiliated researcher
Posttranscriptional Regulation in Adenovirus Infected Cells.
Zhao H, Konzer A, Mi J, ..., Pettersson U, Lind SB
J. Proteome Res. 16 (2) 872-888 [2017-02-03; online 2016-12-13]
Affiliated researcher
A Synthesis of "Dual Warhead" β-Aryl Ethenesulfonyl Fluorides and One-Pot Reaction to β-Sultams.
Chinthakindi PK, Govender KB, Kumar AS, ..., Naicker T, Arvidsson PI
Org. Lett. 19 (3) 480-483 [2017-02-03; online 2017-01-11]
Affiliated researcher
The Human Adrenal Gland Proteome Defined by Transcriptomics and Antibody-Based Profiling.
Bergman J, Botling J, Fagerberg L, ..., Uhlén M, Pontén F
Endocrinology 158 (2) 239-251 [2017-02-01; online 2016-12-03]
Affiliated researcher
Massive parallel sequencing questions the pathogenic role of missense variants in dilated cardiomyopathy.
Dalin MG, Engström PG, Ivarsson EG, ..., Andersson B, Bergo MO
Int. J. Cardiol. 228 (-) 742-748 [2017-02-01; online 2016-11-09]
Affiliated researcher
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies.
Herold N, Rudd SG, Ljungblad L, ..., Helleday T, Schaller T
Nat. Med. 23 (2) 256-263 [2017-02-00; online 2017-01-09]
Affiliated researcher
Self-correcting mismatches during high-fidelity DNA replication.
Fernandez-Leiro R, Conrad J, Yang JC, ..., Scheres SH, Lamers MH
Nat. Struct. Mol. Biol. 24 (2) 140-143 [2017-02-00; online 2017-01-09]
Affiliated researcher
Robust, universal biomarker assay to detect senescent cells in biological specimens.
Evangelou K, Lougiakis N, Rizou SV, ..., Bartek J, Gorgoulis VG
Aging Cell 16 (1) 192-197 [2017-02-00; online 2016-11-17]
Affiliated researcher
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
Schmidt AF, Swerdlow DI, Holmes MV, ..., Hingorani AD, Sattar N
The Lancet Diabetes & Endocrinology 5 (2) 97-105 [2017-02-00; online 2017-02-00]
Affiliated researcher
Opioid precursor protein isoform is targeted to the cell nuclei in the human brain.
Kononenko O, Bazov I, Watanabe H, ..., Yakovleva T, Bakalkin G
Biochim Biophys Acta Gen Subj 1861 (2) 246-255 [2017-02-00; online 2016-11-10]
Affiliated researcher
Mosaicism in health and disease - clones picking up speed.
Forsberg LA, Gisselsson D, Dumanski JP
Nat. Rev. Genet. 18 (2) 128-142 [2017-02-00; online 2016-12-12]
Affiliated researcher
Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.
Romanov RA, Zeisel A, Bakker J, ..., Horvath TL, Harkany T
Nat. Neurosci. 20 (2) 176-188 [2017-02-00; online 2016-12-19]
Affiliated researcher
Mercury Human Exposure in Populations Living Around Lake Tana (Ethiopia).
Habiba G, Abebe G, Bravo AG, ..., Staffan Ǻ, Bishop K
Biol Trace Elem Res 175 (2) 237-243 [2017-02-00; online 2016-06-09]
Affiliated researcher
Antigen receptor stereotypy in chronic lymphocytic leukemia.
Stamatopoulos K, Agathangelidis A, Rosenquist R, Ghia P
Leukemia 31 (2) 282-291 [2017-02-00; online 2016-11-04]
Affiliated researcher
c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas.
Heiland DH, Ferrarese R, Claus R, ..., Nelander S, Carro MS
Oncotarget 8 (4) 6940-6954 [2017-01-24; online 2016-12-31]
Affiliated researcher
Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin.
Jiang Y, Marinescu VD, Xie Y, ..., Nelander S, Uhrbom L
Cell Reports 18 (4) 977-990 [2017-01-24; online 2017-01-26]
Affiliated researcher
Asgard archaea illuminate the origin of eukaryotic cellular complexity.
Zaremba-Niedzwiedzka K, Caceres EF, Saw JH, ..., Spang A, Ettema TJ
Nature 541 (7637) 353-358 [2017-01-19; online 2017-01-11]
Affiliated researcher
Novel genetic loci associated with hippocampal volume.
Hibar DP, Adams HHH, Jahanshad N, ..., Thompson PM, Ikram MA
Nat Commun 8 (-) 13624 [2017-01-18; online 2017-01-18]
Affiliated researcher
Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging.
Zanni G, Michno W, Di Martino E, ..., Blomgren K, Hanrieder J
Sci Rep 7 (-) 40726 [2017-01-18; online 2017-01-18]
SciLifeLab Fellow Wojciech Michno
Targeted DNA sequencing and in situ mutation analysis using mobile phone microscopy.
Kühnemund M, Wei Q, Darai E, ..., Ozcan A, Nilsson M
Nat Commun 8 (-) 13913 [2017-01-17; online 2017-01-17]
Affiliated researcher
Ameloblastoma RNA profiling uncovers a distinct non-coding RNA signature.
Davanian H, Balasiddaiah A, Heymann R, ..., Kruger Weiner C, Chen M
Oncotarget 8 (3) 4530-4542 [2017-01-17; online 2016-12-15]
Affiliated researcher
Architecture of the yeast small subunit processome.
Chaker-Margot M, Barandun J, Hunziker M, Klinge S
Science 355 (6321) - [2017-01-13; online 2016-12-15]
Jonas Barandun SciLifeLab Fellow
Rituximab capping triggers intracellular reorganization of B cells
Koller T, Blok S, Santos AM, ..., Sezgin E, Eggeling C
Matters - (-) - [2017-01-12; online 2017-01-12]
Erdinc Sezgin SciLifeLab Fellow
New insights into the GINS complex explain the controversy between existing structural models.
Carroni M, De March M, Medagli B, ..., Patwardhan A, Onesti S
Sci Rep 7 (-) 40188 [2017-01-10; online 2017-01-10]
Affiliated researcher
Identification of a Novel Autoimmune Peptide Epitope of Prostein in Prostate Cancer.
Pin E, Henjes F, Hong MG, ..., Nilsson P, Schwenk JM
J. Proteome Res. 16 (1) 204-216 [2017-01-06; online 2016-10-24]
Affiliated researcher
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.
Wahl S, Drong A, Lehne B, ..., Grallert H, Chambers JC
Nature 541 (7635) 81-86 [2017-01-05; online 2016-12-21]
Affiliated researcher
HieranoiDB: a database of orthologs inferred by Hieranoid.
Kaduk M, Riegler C, Lemp O, Sonnhammer EL
Nucleic Acids Res. 45 (D1) D687-D690 [2017-01-04; online 2016-10-13]
Affiliated researcher
DisProt 7.0: a major update of the database of disordered proteins.
Piovesan D, Tabaro F, Mičetić I, ..., Tompa P, Tosatto SC
Nucleic Acids Res. 45 (D1) D219-D227 [2017-01-04; online 2016-11-28]
Affiliated researcher
Sex differences in depression during pregnancy and the postpartum period.
Sundström Poromaa I, Comasco E, Georgakis MK, Skalkidou A
J Neurosci Res 95 (1-2) 719-730 [2017-01-02; online 2016-11-22]
Erika Comasco SciLifeLab Fellow
Comprehensive RNA sequencing of healthy human endometrium at two time points of the menstrual cycle.
Sigurgeirsson B, Åmark H, Jemt A, ..., Lundeberg J, Gidlöf S
Biol. Reprod. 96 (1) 24-33 [2017-01-01; online 2017-04-11]
Affiliated researcher
CADEE: Computer-Aided Directed Evolution of Enzymes.
Amrein BA, Steffen-Munsberg F, Szeler I, ..., Kulkarni Y, Kamerlin SCL
IUCrJ 4 (Pt 1) 50-64 [2017-01-01; online 2017-01-01]
Affiliated researcher
Why mitochondria need a genome revisited.
Björkholm P, Ernst AM, Hagström E, Andersson SG
FEBS Lett. 591 (1) 65-75 [2017-01-00; online 2016-12-20]
Affiliated researcher
Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.
Thuresson AC, Van Buggenhout G, Sheth F, ..., Clayton Smith J, Soussi Zander C
Clin. Genet. 91 (1) 106-110 [2017-01-00; online 2016-06-02]
Affiliated researcher
Targeting TGF-β Signaling in Cancer.
Colak S, Ten Dijke P
Trends Cancer 3 (1) 56-71 [2017-01-00; online 2017-01-03]
Affiliated researcher
Mutational analysis of protein folding inside the ribosome exit tunnel.
Farías-Rico JA, Goetz SK, Marino J, von Heijne G
FEBS Lett. 591 (1) 155-163 [2017-01-00; online 2016-12-20]
Affiliated researcher
Multispecies genetic structure and hybridization in the Betula genus across Eurasia.
Tsuda Y, Semerikov V, Sebastiani F, Vendramin GG, Lascoux M
Mol. Ecol. 26 (2) 589-605 [2017-01-00; online 2016-12-24]
Affiliated researcher
Lake bacterioplankton dynamics over diurnal timescales
Grubisic LM, Bertilsson S, Eiler A, ..., Riemann L, Beier S
Freshw Biol 62 (1) 191-204 [2017-01-00; online 2016-12-16]
Affiliated researcher
Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity.
Kegel ME, Johansson V, Wetterberg L, ..., Hultman CM, Erhardt S
Psychiatry Res 247 (-) 105-112 [2017-01-00; online 2016-11-16]
Affiliated researcher
Investigating kinship of Neolithic post-LBK human remains from Krusza Zamkowa, Poland using ancient DNA.
Juras A, Chyleński M, Krenz-Niedbała M, ..., Jakobsson M, Dabert M
Forensic Sci Int Genet 26 (-) 30-39 [2017-01-00; online 2016-10-14]
Affiliated researcher
Human immune system variation.
Brodin P, Davis MM
Nat. Rev. Immunol. 17 (1) 21-29 [2017-01-00; online 2016-12-05]
Affiliated researcher
Flow-cytometric screening of aggregation-inhibitors using a fluorescence-assisted intracellular method.
Lindberg H, Sandersjöö L, Meister SW, ..., Löfblom J, Ståhl S
Biotechnol J 12 (1) - [2017-01-00; online 2016-12-01]
Affiliated researcher
Expression of possible targets for new proteasome inhibitors in diffuse large B-cell lymphoma.
Delforoush M, Berglund M, Edqvist PH, ..., Gullbo J, Enblad G
Eur. J. Haematol. 98 (1) 52-56 [2017-01-00; online 2016-07-12]
Affiliated researcher
Evolutionary engineering reveals divergent paths when yeast is adapted to different acidic environments.
Fletcher E, Feizi A, Bisschops MMM, ..., Siewers V, Nielsen J
Metab. Eng. 39 (-) 19-28 [2017-01-00; online 2016-11-02]
Affiliated researcher
Environmental Risk Factors for Diabetes Mellitus in Cats.
Öhlund M, Egenvall A, Fall T, ..., Röcklinsberg H, Holst BS
J. Vet. Intern. Med. 31 (1) 29-35 [2017-01-00; online 2016-12-01]
Affiliated researcher
Elevated levels of circulating CDH5 and FABP1 in association with human drug-induced liver injury.
Mikus M, Drobin K, Gry M, ..., Nilsson P, Schuppe-Koistinen I
Liver Int. 37 (1) 132-140 [2017-01-00; online 2016-06-22]
Affiliated researcher
Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.
Häggblad Sahlberg S, Mortensen AC, Haglöf J, ..., Stenerlöw B, Nestor M
Int. J. Oncol. 50 (1) 5-14 [2017-01-00; online 2016-11-18]
Affiliated researcher
Deep Fish.
Ishaq O, Sadanandan SK, Wählby C
SLAS Discov 22 (1) 102-107 [2017-01-00; online 2016-09-26]
Affiliated researcher
Cost and clinical outcome of islet transplantation in Norway 2010-2015.
Schive SW, Foss A, Sahraoui A, ..., Mishra V, Scholz H
Clin Transplant 31 (1) - [2017-01-00; online 2016-12-09]
Affiliated researcher
Both maternal and offspring Elovl2 genotypes determine systemic DHA levels in perinatal mice.
Pauter AM, Trattner S, Gonzalez-Bengtsson A, ..., Dethlefsen O, Jacobsson A
J. Lipid Res. 58 (1) 111-123 [2017-01-00; online 2016-11-18]
Affiliated researcher
A multi-step peptidolytic cascade for amino acid recovery in chloroplasts.
Teixeira PF, Kmiec B, Branca RM, ..., Lehtiö J, Glaser E
Nat. Chem. Biol. 13 (1) 15-17 [2017-01-00; online 2016-10-31]
Affiliated researcher
Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients
Niinivirta M, Enblad G, Edqvist PH, ..., Dragomir A, Ullenhag GJ
J. Cancer 8 (19) 3975-3983 [2017-00-00; online 2017-00-00]
Affiliated researcher
Slipdisc: a versatile sample preparation platform for point of care diagnostics
Banerjee I, Salih T, Ramachandraiah H, ..., Karlsson M, Russom A
RSC Adv. 7 (56) 35048-35054 [2017-00-00; online 2017-00-00]
Affiliated researcher
Lignin depolymerization to monophenolic compounds in a flow-through system
Kumaniaev I, Subbotina E, Sävmarker J, ..., Galkin MV, Samec JSM
Green Chem. 19 (24) 5767-5771 [2017-00-00; online 2017-00-00]
Affiliated researcher
Evolution of Resistance to Insecticide in Disease Vectors
Labbé P, David JP, Alout H, ..., Pasteur N, Weill M
- - (-) 313-339 [2017-00-00; online 2017-00-00]
Pascal Milesi SciLifeLab Fellow
TGF-β Affects the Differentiation of Human GM-CSF
Éliás S, Schmidt A, Kannan V, Andersson J, Tegnér J
Front Immunol 7 (-) 603 [2016-12-23; online 2016-12-23]
Affiliated researcher
Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity.
Corcoran MM, Phad GE, Vázquez Bernat , ..., Martin M, Karlsson Hedestam GB
Nat Commun 7 (-) 13642 [2016-12-20; online 2016-12-20]
Affiliated researcher
Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia.
Pandzic T, Larsson J, He L, ..., Sjöblom T, Hellström M
Clin. Cancer Res. 22 (24) 6217-6227 [2016-12-15; online 2016-03-08]
Affiliated researcher
FANCM c.5101C>T mutation associates with breast cancer survival and treatment outcome.
Kiiski JI, Fagerholm R, Tervasmäki A, ..., Blomqvist C, Nevanlinna H
Int. J. Cancer 139 (12) 2760-2770 [2016-12-15; online 2016-09-19]
Affiliated researcher
The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.
van Kempen LC, Redpath M, Elchebly M, ..., Feunteun J, Spatz A
Sci Transl Med 8 (369) 369ra177 [2016-12-14; online 2016-12-16]
Affiliated researcher
The In Vitro Stability of Circulating Tumour DNA.
Henao Diaz E, Yachnin J, Grönberg H, Lindberg J
PLoS ONE 11 (12) e0168153 [2016-12-13; online 2016-12-13]
Affiliated researcher
Serum Autoantibody Profiling of Patients with Paraneoplastic and Non-Paraneoplastic Autoimmune Retinopathy.
Ten Berge JC, van Rosmalen J, Vermeer J, ..., Rothova A, Schreurs MW
PLoS ONE 11 (12) e0167909 [2016-12-08; online 2016-12-08]
Affiliated researcher
PDGFB, a new candidate plasma biomarker for venous thromboembolism: results from the VEREMA affinity proteomics study.
Bruzelius M, Iglesias MJ, Hong MG, ..., Trégouët DA, Odeberg J
Blood 128 (23) e59-e66 [2016-12-08; online 2016-10-14]
Affiliated researcher
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri L, Noerenberg D, Young E, ..., Rosenquist R, Damm F
Blood 128 (23) 2666-2670 [2016-12-08; online 2016-09-26]
Affiliated researcher
Membrane Anchoring and Ion-Entry Dynamics in P-type ATPase Copper Transport.
Grønberg C, Sitsel O, Lindahl E, Gourdon P, Andersson M
Biophys. J. 111 (11) 2417-2429 [2016-12-06; online 2016-12-08]
Affiliated researcher
The Effect of Moment of Inertia on the Liquids in Centrifugal Microfluidics.
Pishbin E, Eghbal M, Fakhari S, Kazemzadeh A, Navidbakhsh M
Micromachines (Basel) 7 (12) - [2016-12-02; online 2016-12-02]
Affiliated researcher
The topogenic function of S4 promotes membrane insertion of the voltage-sensor domain in the KvAP channel.
Mishima E, Sato Y, Nanatani K, ..., Sakaguchi M, Uozumi N
Biochem. J. 473 (23) 4361-4372 [2016-12-01; online 2016-09-30]
Affiliated researcher
Validation and development of MTH1 inhibitors for treatment of cancer.
Warpman Berglund U, Sanjiv K, Gad H, ..., Scobie M, Helleday T
Ann. Oncol. 27 (12) 2275-2283 [2016-12-00; online 2016-11-08]
Affiliated researcher
The disappearing San of southeastern Africa and their genetic affinities.
Schlebusch CM, Prins F, Lombard M, Jakobsson M, Soodyall H
Hum. Genet. 135 (12) 1365-1373 [2016-12-00; online 2016-09-20]
Affiliated researcher
Structural and conformational determinants of macrocycle cell permeability.
Over B, Matsson P, Tyrchan C, ..., Duvall JR, Kihlberg J
Nat. Chem. Biol. 12 (12) 1065-1074 [2016-12-00; online 2016-10-17]
Affiliated researcher
Squalene-hopene cyclases-evolution, dynamics and catalytic scope.
Syrén PO, Henche S, Eichler A, Nestl BM, Hauer B
Curr. Opin. Struct. Biol. 41 (-) 73-82 [2016-12-00; online 2016-06-20]
Affiliated researcher
Novel genetic loci underlying human intracranial volume identified through genome-wide association.
Adams HH, Hibar DP, Chouraki V, ..., Ikram MA, Thompson PM
Nat. Neurosci. 19 (12) 1569-1582 [2016-12-00; online 2016-10-03]
Affiliated researcher
Heparanase Promotes Glioma Progression and Is Inversely Correlated with Patient Survival.
Kundu S, Xiong A, Spyrou A, ..., Li JP, Forsberg-Nilsson K
Mol. Cancer Res. 14 (12) 1243-1253 [2016-12-00; online 2016-08-26]
Affiliated researcher
Genome-wide analysis identifies 12 loci influencing human reproductive behavior.
Barban N, Jansen R, de Vlaming R, ..., Snieder H, Mills MC
Nat. Genet. 48 (12) 1462-1472 [2016-12-00; online 2016-10-31]
Affiliated researcher
Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease.
Eriksson D, Bianchi M, Landegren N, ..., Kämpe O, Pielberg GR
J. Intern. Med. 280 (6) 595-608 [2016-12-00; online 2016-11-02]
Affiliated researcher
Exploring the oviductal fluid proteome by a lectin-based affinity approach.
Yu H, Reiser J, Besenfelder U, ..., Artemenko K, Mayrhofer C
Proteomics 16 (23) 2962-2966 [2016-12-00; online 2016-11-09]
Affiliated researcher
Early Perspective.
Seashore-Ludlow B, Lundbäck T
J Biomol Screen 21 (10) 1019-1033 [2016-12-00; online 2016-07-20]
Affiliated researcher
Distribution and expression of microbial rhodopsins in the Baltic Sea and adjacent waters.
Brindefalk B, Ekman M, Ininbergs K, ..., Pinhassi J, Bergman B
Environ. Microbiol. 18 (12) 4442-4455 [2016-12-00; online 2016-07-14]
Affiliated researcher
Base sequence specificity of counterion binding to DNA: what can MD simulations tell us?
Atzori A, Liggi S, Laaksonen A, ..., Saba G, Mocci F
Can. J. Chem. 94 (12) 1181-1188 [2016-12-00; online 2016-12-00]
Affiliated researcher
DNA methylation patterns associated with oxidative stress in an ageing population.
Hedman ÅK, Zilmer M, Sundström J, Lind L, Ingelsson E
BMC Med Genomics 9 (1) 72 [2016-11-25; online 2016-11-25]
Affiliated researcher
The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.
Scharaw S, Iskar M, Ori A, ..., Bork P, Pepperkok R
J. Cell Biol. 215 (4) 543-558 [2016-11-21; online 2016-11-08]
Affiliated researcher
An automated approach to prepare tissue-derived spatially barcoded RNA-sequencing libraries.
Jemt A, Salmén F, Lundmark A, ..., Yucel-Lindberg T, Lundeberg J
Sci Rep 6 (-) 37137 [2016-11-16; online 2016-11-16]
Affiliated researcher
Periostin is identified as a putative metastatic marker in breast cancer-derived exosomes.
Vardaki I, Ceder S, Rutishauser D, ..., Foukakis T, Panaretakis T
Oncotarget 7 (46) 74966-74978 [2016-11-15; online 2016-09-03]
Affiliated researcher
Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease.
Matsson H, Söderhäll C, Einarsdottir E, ..., Lundbäck B, Klar J
BMC Pulm Med 16 (1) 146 [2016-11-11; online 2016-11-11]
Affiliated researcher
Probabilistic inference of lateral gene transfer events.
Khan MA, Mahmudi O, Ullah I, Arvestad L, Lagergren J
BMC Bioinformatics 17 (Suppl 14) 431 [2016-11-11; online 2016-11-11]
Affiliated researcher
The stem osteichthyan Andreolepis and the origin of tooth replacement.
Chen D, Blom H, Sanchez S, Tafforeau P, Ahlberg PE
Nature 539 (7628) 237-241 [2016-11-10; online 2016-10-17]
Affiliated researcher
Cohort profile: the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC).
Jääskeläinen T, Heinonen S, Kajantie E, ..., Laivuori H, FINNPEC Study Group
BMJ Open 6 (11) e013148 [2016-11-10; online 2016-11-10]
Affiliated researcher
Immunohistochemical Typing of Adenocarcinomas of the Pancreatobiliary System Improves Diagnosis and Prognostic Stratification.
Fernández Moro C, Fernandez-Woodbridge A, Alistair D'souza M, ..., Verbeke C, Bozóky B
PLoS ONE 11 (11) e0166067 [2016-11-09; online 2016-11-09]
Affiliated researcher
Case-specific potentiation of glioblastoma drugs by pterostilbene.
Schmidt L, Baskaran S, Johansson P, ..., Krona C, Nelander S
Oncotarget 7 (45) 73200-73215 [2016-11-08; online 2016-10-01]
Affiliated researcher
Looking for Missing Proteins in the Proteome of Human Spermatozoa: An Update.
Vandenbrouck Y, Lane L, Carapito C, ..., Garin J, Pineau C
J. Proteome Res. 15 (11) 3998-4019 [2016-11-04; online 2016-08-23]
Affiliated researcher
Clonal B-cell lymphocytosis of marginal zone origin.
Xochelli A, Oscier D, Stamatopoulos K
Best Pract Res Clin Haematol 30 (1-2) 77-83 [2016-11-04; online 2016-11-04]
Affiliated researcher
Maps of context-dependent putative regulatory regions and genomic signal interactions.
Diamanti K, Umer HM, Kruczyk M, ..., Wadelius C, Komorowski J
Nucleic Acids Res. 44 (19) 9110-9120 [2016-11-02; online 2016-09-12]
Affiliated researcher
The H3 chaperone function of NASP is conserved in Arabidopsis.
Maksimov V, Nakamura M, Wildhaber T, ..., Bergquist J, Hennig L
Plant J. 88 (3) 425-436 [2016-11-00; online 2016-09-15]
Affiliated researcher
Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia.
Bereczki E, Francis PT, Howlett D, ..., Ballard C, Aarsland D
Alzheimers Dement 12 (11) 1149-1158 [2016-11-00; online 2016-05-22]
Affiliated researcher
Screening out irrelevant cell-based models of disease.
Horvath P, Aulner N, Bickle M, ..., von Schantz C, Carragher NO
Nat Rev Drug Discov 15 (11) 751-769 [2016-11-00; online 2016-09-12]
Affiliated researcher
Relating fitness to long-term environmental variations in natura.
Milesi P, Lenormand T, Lagneau C, Weill M, Labbé P
Mol. Ecol. 25 (21) 5483-5499 [2016-11-00; online 2016-10-14]
Pascal Milesi SciLifeLab Fellow
Migratory activation of parasitized dendritic cells by the protozoan Toxoplasma gondii 14-3-3 protein.
Weidner JM, Kanatani S, Uchtenhagen H, ..., Achour A, Barragan A
Cell. Microbiol. 18 (11) 1537-1550 [2016-11-00; online 2016-05-06]
Affiliated researcher
Methane oxidation at the water‐ice interface of an ice‐covered lake
Ricão Canelhas M, Denfeld BA, Weyhenmeyer GA, Bastviken D, Bertilsson S
Limnol. Oceanogr. 61 (S1) S78-S90 [2016-11-00; online 2016-03-29]
Affiliated researcher
MID-PREGNANCY CORTICOTROPIN-RELEASING HORMONE LEVELS IN ASSOCIATION WITH POSTPARTUM DEPRESSIVE SYMPTOMS.
Iliadis SI, Sylvén S, Hellgren C, ..., Sundström Poromaa I, Skalkidou A
Depress Anxiety 33 (11) 1023-1030 [2016-11-00; online 2016-05-27]
Erika Comasco SciLifeLab Fellow
Long-term outcome in young women with breast cancer: a population-based study.
Fredholm H, Magnusson K, Lindström LS, ..., Frisell J, Fredriksson I
Breast Cancer Res. Treat. 160 (1) 131-143 [2016-11-00; online 2016-09-13]
Affiliated researcher
Inferring Past Effective Population Size from Distributions of Coalescent Times.
Gattepaille L, Günther T, Jakobsson M
Genetics 204 (3) 1191-1206 [2016-11-00; online 2016-09-16]
Affiliated researcher
High migration rates shape the postglacial history of amphi-Atlantic bryophytes.
Désamoré A, Patiño J, Mardulyn P, ..., Laenen B, Vanderpoorten A
Mol. Ecol. 25 (21) 5568-5584 [2016-11-00; online 2016-10-17]
Affiliated researcher
Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia.
Parker H, Rose-Zerilli MJ, Larrayoz M, ..., Oscier DG, Strefford JC
Leukemia 30 (11) 2179-2186 [2016-11-00; online 2016-05-20]
Affiliated researcher
Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia.
Teppo S, Laukkanen S, Liuksiala T, ..., Heinäniemi M, Lohi O
Genome Res. 26 (11) 1468-1477 [2016-11-00; online 2016-09-12]
Affiliated researcher
Diet adaptation in dog reflects spread of prehistoric agriculture.
Arendt M, Cairns KM, Ballard JW, Savolainen P, Axelsson E
Heredity (Edinb) 117 (5) 301-306 [2016-11-00; online 2016-07-13]
Affiliated researcher
Amy2B copy number variation reveals starch diet adaptations in ancient European dogs.
Ollivier M, Tresset A, Bastian F, ..., Hitte C, Hänni C
R Soc Open Sci 3 (11) 160449 [2016-11-00; online 2016-11-09]
Affiliated researcher
Rawcopy: Improved copy number analysis with Affymetrix arrays.
Mayrhofer M, Viklund B, Isaksson A
Sci Rep 6 (-) 36158 [2016-10-31; online 2016-10-31]
Affiliated researcher
Thermodynamics of Nanobody Binding to Lactose Permease.
Hariharan P, Andersson M, Jiang X, ..., Kaback HR, Guan L
Biochemistry 55 (42) 5917-5926 [2016-10-25; online 2016-10-12]
Affiliated researcher
Gene-specific correlation of RNA and protein levels in human cells and tissues.
Edfors F, Danielsson F, Hallström BM, ..., Forsström B, Uhlén M
Mol Syst Biol 12 (10) 883 [2016-10-20; online 2016-10-20]
Affiliated researcher
FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.
Suryo Rahmanto A, Savov V, Brunner A, ..., Swartling FJ, Sangfelt O
EMBO J. 35 (20) 2192-2212 [2016-10-17; online 2016-09-13]
Affiliated researcher
Binding of Pollutants to Biomolecules: A Simulation Study.
Yildirim A, Zhang J, Manzetti S, van der Spoel D
Chem. Res. Toxicol. 29 (10) 1679-1688 [2016-10-17; online 2016-09-13]
Affiliated researcher
Reconstructing a hydrogen-driven microbial metabolic network in Opalinus Clay rock.
Bagnoud A, Chourey K, Hettich RL, ..., Schwyn B, Bernier-Latmani R
Nat Commun 7 (-) 12770 [2016-10-14; online 2016-10-14]
Affiliated researcher
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Segerstolpe Å, Palasantza A, Eliasson P, ..., Ämmälä C, Sandberg R
Cell Metab. 24 (4) 593-607 [2016-10-11; online 2016-09-22]
Affiliated researcher
Hydrophobic Clusters Raise the Threshold Hydrophilicity for Insertion of Transmembrane Sequences in Vivo.
Stone TA, Schiller N, Workewych N, von Heijne G, Deber CM
Biochemistry 55 (40) 5772-5779 [2016-10-11; online 2016-09-29]
Affiliated researcher
Multidimensional Normalization to Minimize Plate Effects of Suspension Bead Array Data.
Hong MG, Lee W, Nilsson P, Pawitan Y, Schwenk JM
J. Proteome Res. 15 (10) 3473-3480 [2016-10-07; online 2016-09-12]
Affiliated researcher
Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells.
La Manno G, Gyllborg D, Codeluppi S, ..., Arenas E, Linnarsson S
Cell 167 (2) 566-580.e19 [2016-10-06; online 2016-10-08]
Affiliated researcher
ProQ3: Improved model quality assessments using Rosetta energy terms.
Uziela K, Shu N, Wallner B, Elofsson A
Sci Rep 6 (-) 33509 [2016-10-04; online 2016-10-04]
Affiliated researcher
The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation.
Jouhilahti EM, Madissoon E, Vesterlund L, ..., Katayama S, Kere J
Development 143 (19) 3459-3469 [2016-10-01; online 2016-08-30]
Affiliated researcher
Whole-Exome Sequencing Suggests LAMB3 as a Susceptibility Gene for Morbid Obesity.
Jiao H, Kulyté A, Näslund E, ..., Arner P, Dahlman I
Diabetes 65 (10) 2980-2989 [2016-10-00; online 2016-07-18]
Affiliated researcher
Soluble CD93 Is Involved in Metabolic Dysregulation but Does Not Influence Carotid Intima-Media Thickness.
Strawbridge RJ, Hilding A, Silveira A, ..., Bäcklund A, IMPROVE Study Group
Diabetes 65 (10) 2888-2899 [2016-10-00; online 2016-09-24]
Affiliated researcher
Mutations in HECW2 are associated with intellectual disability and epilepsy.
Halvardson J, Zhao JJ, Zaghlool A, ..., Thuresson AC, Feuk L
J. Med. Genet. 53 (10) 697-704 [2016-10-00; online 2016-06-22]
Affiliated researcher
Metabolomic Quality Assessment of EDTA Plasma and Serum Samples.
Malm L, Tybring G, Moritz T, Landin B, Galli J
Biopreserv Biobank 14 (5) 416-423 [2016-10-00; online 2016-06-27]
Affiliated researcher
Functional Metabolomics Describes the Yeast Biosynthetic Regulome
Mülleder M, Calvani E, Alam MT, ..., Zelezniak A, Ralser M
Cell 167 (2) 553-565.e12 [2016-10-00; online 2016-10-00]
Aleksej Zelezniak SciLifeLab Fellow
Elevated Basal Insulin Secretion in Type 2 Diabetes Caused by Reduced Plasma Membrane Cholesterol.
Nagaraj V, Kazim AS, Helgeson J, ..., Zhang E, Renström E
Mol. Endocrinol. 30 (10) 1059-1069 [2016-10-00; online 2016-08-17]
Affiliated researcher
Effects of multiple dimensions of bacterial diversity on functioning, stability and multifunctionality.
Roger F, Bertilsson S, Langenheder S, Osman OA, Gamfeldt L
Ecology 97 (10) 2716-2728 [2016-10-00; online 2016-09-15]
Affiliated researcher
DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands.
Wahlberg P, Lundmark A, Nordlund J, ..., Lönnerholm G, Syvänen AC
Epigenomics 8 (10) 1367-1387 [2016-10-00; online 2016-08-23]
Affiliated researcher
Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden.
Verhoef TI, Redekop WK, Langenskiold S, ..., Hughes DA, Pirmohamed M
Pharmacogenomics J. 16 (5) 478-484 [2016-10-00; online 2016-06-07]
Affiliated researcher
Biophysics in drug discovery: impact, challenges and opportunities.
Renaud JP, Chung CW, Danielson UH, ..., Hubbard RE, Nar H
Nat Rev Drug Discov 15 (10) 679-698 [2016-10-00; online 2016-08-12]
Affiliated researcher
Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis.
Landegren N, Pourmousa Lindberg M, Skov J, ..., Fenton RA, Kämpe O
J. Am. Soc. Nephrol. 27 (10) 3220-3228 [2016-10-00; online 2016-03-16]
Affiliated researcher
An introduction to plant phylogenomics with a focus on palms
Barrett CF, Bacon CD, Antonelli A, Cano Á, Hofmann T
Bot. J. Linn. Soc. 182 (2) 234-255 [2016-10-00; online 2016-03-18]
DDLS Fellow Tobias Andermann
A proposal for validation of antibodies.
Uhlen M, Bandrowski A, Carr S, ..., Snyder M, Yamamoto T
Nat. Methods 13 (10) 823-827 [2016-10-00; online 2016-09-05]
Affiliated researcher
Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.
Butler LM, Hallström BM, Fagerberg L, ..., Renné T, Odeberg J
Cell Systems 3 (3) 287-301.e3 [2016-09-28; online 2016-09-15]
Affiliated researcher
Exploration of high-density protein microarrays for antibody validation and autoimmunity profiling.
Sjöberg R, Mattsson C, Andersson E, ..., Ayoglu B, Nilsson P
N Biotechnol 33 (5 Pt A) 582-592 [2016-09-25; online 2015-09-28]
Affiliated researcher
RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma.
Sakurai T, Isogaya K, Sakai S, ..., Miyazono K, Koinuma D
Oncogene 35 (38) 5000-5009 [2016-09-22; online 2016-02-29]
Affiliated researcher
Functional and Structural Consequences of Nine
de Paula Michelatto D, Karlsson L, Lusa AL, ..., de Mello MP, Lajic S
Int J Endocrinol 2016 (-) 4209670 [2016-09-19; online 2016-09-19]
Affiliated researcher
XMetDB: an open access database for xenobiotic metabolism.
Spjuth O, Rydberg P, Willighagen EL, Evelo CT, Jeliazkova N
J Cheminform 8 (-) 47 [2016-09-15; online 2016-09-15]
Affiliated researcher
NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine.
Valerie NC, Hagenkort A, Page BD, ..., Jemth AS, Helleday T
Cancer Res. 76 (18) 5501-5511 [2016-09-15; online 2016-08-16]
Affiliated researcher
Life history of the stem tetrapod Acanthostega revealed by synchrotron microtomography.
Sanchez S, Tafforeau P, Clack JA, Ahlberg PE
Nature 537 (7620) 408-411 [2016-09-15; online 2016-09-07]
Affiliated researcher
Analysis with the exome array identifies multiple new independent variants in lipid loci.
Kanoni S, Masca NG, Stirrups KE, ..., Samani NJ, Deloukas P
Hum. Mol. Genet. 25 (18) 4094-4106 [2016-09-15; online 2016-07-27]
Affiliated researcher
Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.
Morgado-Palacin I, Day A, Murga M, ..., Nussenzweig A, Fernandez-Capetillo O
Sci Signal 9 (445) ra91 [2016-09-13; online 2016-09-13]
Affiliated researcher
Efficacy of ATR inhibitors as single agents in Ewing sarcoma.
Nieto-Soler M, Morgado-Palacin I, Lafarga V, ..., Nussenzweig A, Fernandez-Capetillo O
Oncotarget 7 (37) 58759-58767 [2016-09-13; online 2016-09-01]
Affiliated researcher
The helical structure of DNA facilitates binding
Berg OG, Mahmutovic A, Marklund E, Elf J
J. Phys. A: Math. Theor. 49 (36) 364002 [2016-09-09; online 2016-08-16]
Affiliated researcher
NDST2 (N-Deacetylase/N-Sulfotransferase-2) Enzyme Regulates Heparan Sulfate Chain Length.
Deligny A, Dierker T, Dagälv A, ..., Merry CLR, Kjellén L
J. Biol. Chem. 291 (36) 18600-18607 [2016-09-02; online 2016-07-07]
Affiliated researcher
Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity.
Mahajan A, Rodan AR, Le TH, ..., Morris AP, Franceschini N
Am. J. Hum. Genet. 99 (3) 636-646 [2016-09-01; online 2016-09-03]
Affiliated researcher
POLD3 Is Haploinsufficient for DNA Replication in Mice.
Murga M, Lecona E, Kamileri I, ..., Halazonetis TD, Fernandez-Capetillo O
Mol. Cell 63 (5) 877-883 [2016-09-01; online 2016-08-11]
Affiliated researcher
Benchmarking the next generation of homology inference tools.
Saripella GV, Sonnhammer EL, Forslund K
Bioinformatics 32 (17) 2636-2641 [2016-09-01; online 2016-06-01]
Affiliated researcher
A novel variant in MYLK causes thoracic aortic dissections: genotypic and phenotypic description.
Hannuksela M, Stattin EL, Klar J, ..., Sörensen K, Carlberg B
BMC Med. Genet. 17 (1) 61 [2016-09-01; online 2016-09-01]
Affiliated researcher
Tissue microarray profiling in human heart failure.
Lal S, Nguyen L, Tezone R, ..., Li A, Dos Remedios C
Proteomics 16 (17) 2319-2326 [2016-09-00; online 2016-08-11]
Affiliated researcher
The Impact of Endurance Training on Human Skeletal Muscle Memory, Global Isoform Expression and Novel Transcripts.
Lindholm ME, Giacomello S, Werne Solnestam B, ..., Kjellqvist S, Sundberg CJ
PLoS Genet 12 (9) e1006294 [2016-09-00; online 2016-09-22]
Affiliated researcher
Strategies to improve usability and preserve accuracy in biological sequence databases.
Bengtsson-Palme J, Boulund F, Edström R, ..., Sanli K, Thorell K
Proteomics 16 (18) 2454-2460 [2016-09-00; online 2016-08-17]
DDLS Fellow Johan Bengtsson-Palme
Repeated LPS Injection Induces Distinct Changes in the Kynurenine Pathway in Mice.
Larsson MK, Faka A, Bhat M, ..., Schwieler L, Erhardt S
Neurochem. Res. 41 (9) 2243-2255 [2016-09-00; online 2016-05-10]
Affiliated researcher
Protein profiles of CCL5, HPGDS, and NPSR1 in plasma reveal association with childhood asthma.
Hamsten C, Häggmark A, Grundström J, ..., Nilsson P, van Hage M
Allergy 71 (9) 1357-1361 [2016-09-00; online 2016-05-25]
Affiliated researcher
Positron Emission Tomography to Assess the Outcome of Intraportal Islet Transplantation.
Eriksson O, Selvaraju R, Eich T, ..., Lundgren T, Korsgren O
Diabetes 65 (9) 2482-2489 [2016-09-00; online 2016-06-20]
Olof Eriksson SciLifeLab Fellow
Is low molecular weight hyaluronan an early indicator of disease in avian systemic sclerosis?
Kerje S, Hellman U, Do L, ..., Engström-Laurent A, Lindqvist U
Connect. Tissue Res. 57 (5) 337-346 [2016-09-00; online 2016-05-02]
Affiliated researcher
Conformation Traits and Gaits in the Icelandic Horse are Associated with Genetic Variants in Myostatin (MSTN).
François L, Jäderkvist Fegraeus K, Eriksson S, ..., Lindgren G, Velie BD
J. Hered. 107 (5) 431-437 [2016-09-00; online 2016-05-13]
Affiliated researcher
Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond.
Rosenquist R, Rosenwald A, Du MQ, ..., Stamatopoulos K, European Research Initiative on CLL (ERIC) and the European Association for Haematopathology (EAHP)
Haematologica 101 (9) 1002-1009 [2016-09-00; online 2016-09-02]
Affiliated researcher
Autoantibody targets in vaccine-associated narcolepsy.
Häggmark-Månberg A, Zandian A, Forsström B, ..., Olsson T, Nilsson P
Autoimmunity 49 (6) 421-433 [2016-09-00; online 2016-05-20]
Affiliated researcher
A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment.
Zaghlool A, Halvardson J, Zhao JJ, ..., Thuresson AC, Feuk L
Hum. Mutat. 37 (9) 964-975 [2016-09-00; online 2016-07-08]
Affiliated researcher
A Rickettsiales symbiont of amoebae with ancient features.
Schulz F, Martijn J, Wascher F, ..., Ettema TJ, Horn M
Environ. Microbiol. 18 (8) 2326-2342 [2016-09-00; online 2015-06-05]
Affiliated researcher
Origin of the U87MG glioma cell line: Good news and bad news.
Allen M, Bjerke M, Edlund H, Nelander S, Westermark B
Sci Transl Med 8 (354) 354re3 [2016-08-31; online 2016-09-02]
Affiliated researcher
The Adipose Transcriptional Response to Insulin Is Determined by Obesity, Not Insulin Sensitivity.
Rydén M, Hrydziuszko O, Mileti E, ..., Daub CO, Arner P
Cell Reports 16 (9) 2317-2326 [2016-08-30; online 2016-08-18]
Affiliated researcher
Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study.
van der Laan SW, Fall T, Soumaré A, ..., Holmes MV, Asselbergs FW
J. Am. Coll. Cardiol. 68 (9) 934-945 [2016-08-30; online 2016-08-27]
Affiliated researcher
The Competing Mechanisms of Phosphate Monoester Dianion Hydrolysis.
Duarte F, Barrozo A, Åqvist J, Williams NH, Kamerlin SC
J. Am. Chem. Soc. 138 (33) 10664-10673 [2016-08-24; online 2016-08-15]
Affiliated researcher
Enantioselective Organocatalyzed Transformations of β-Ketoesters.
Govender T, Arvidsson PI, Maguire GE, Kruger HG, Naicker T
Chem. Rev. 116 (16) 9375-9437 [2016-08-24; online 2016-07-27]
Affiliated researcher
An RGS2 3'UTR polymorphism is associated with preeclampsia in overweight women.
Karppanen T, Kaartokallio T, Klemetti MM, ..., Staff AC, Laivuori H
BMC Genet. 17 (1) 121 [2016-08-24; online 2016-08-24]
Affiliated researcher
Visualizing the Nonhomogeneous Structure of RAD51 Filaments Using Nanofluidic Channels.
Fornander LH, Frykholm K, Fritzsche J, ..., Modesti M, Westerlund F
Langmuir 32 (33) 8403-8412 [2016-08-23; online 2016-08-12]
Affiliated researcher
Ras and TGF-β signaling enhance cancer progression by promoting the ΔNp63 transcriptional program.
Vasilaki E, Morikawa M, Koinuma D, ..., Miyazono K, Heldin CH
Sci Signal 9 (442) ra84 [2016-08-23; online 2016-08-23]
Affiliated researcher
Multiplex PCB-based electrochemical detection of cancer biomarkers using MLPA-barcode approach.
Sánchez JL, Henry OY, Joda H, ..., Riley I, O'Sullivan CK
Biosens Bioelectron 82 (-) 224-232 [2016-08-15; online 2016-04-07]
Affiliated researcher
Stratification of responders towards eculizumab using a structural epitope mapping strategy.
Volk AL, Hu FJ, Berglund MM, ..., Uhlen M, Rockberg J
Sci Rep 6 (-) 31365 [2016-08-11; online 2016-08-11]
Affiliated researcher
Global profiling of SRP interaction with nascent polypeptides.
Schibich D, Gloge F, Pöhner I, ..., Bukau B, Kramer G
Nature 536 (7615) 219-223 [2016-08-11; online 2016-08-03]
Affiliated researcher
Large-scale ligand-based predictive modelling using support vector machines.
Alvarsson J, Lampa S, Schaal W, ..., Wikberg JE, Spjuth O
J Cheminform 8 (-) 39 [2016-08-10; online 2016-08-10]
Affiliated researcher
Role of Conserved Gly-Gly Pairs on the Periplasmic Side of LacY.
Jiang X, Andersson M, Chau BT, ..., Villafuerte MK, Kaback HR
Biochemistry 55 (31) 4326-4332 [2016-08-09; online 2016-08-01]
Affiliated researcher
A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection.
López-Saavedra A, Gómez-Cabello D, Domínguez-Sánchez MS, ..., Bartek J, Huertas P
Nat Commun 7 (-) 12364 [2016-08-09; online 2016-08-09]
Affiliated researcher
Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.
Gerling M, Büller NV, Kirn LM, ..., van den Brink GR, Toftgård R
Nat Commun 7 (-) 12321 [2016-08-05; online 2016-08-05]
Affiliated researcher
Photoswitchable Spiropyran Dyads for Biological Imaging.
Xiong Y, Rivera-Fuentes P, Sezgin E, ..., Eggeling C, Anderson HL
Org. Lett. 18 (15) 3666-3669 [2016-08-05; online 2016-07-26]
Erdinc Sezgin SciLifeLab Fellow
Integration of a Droplet-Based Microfluidic System and Silicon Nanoribbon FET Sensor.
Afrasiabi R, Soderberg LM, Joensson HN, ..., Andersson Svahn H, Linnros J
Micromachines (Basel) 7 (8) - [2016-08-05; online 2016-08-05]
Affiliated researcher
The genetic architecture of type 2 diabetes.
Fuchsberger C, Flannick J, Teslovich TM, ..., Altshuler D, McCarthy MI
Nature 536 (7614) 41-47 [2016-08-04; online 2016-07-11]
Affiliated researcher
The chaperone co-inducer BGP-15 alleviates ventilation-induced diaphragm dysfunction.
Salah H, Li M, Cacciani N, ..., Salviati L, Larsson L
Sci Transl Med 8 (350) 350ra103 [2016-08-03; online 2016-08-05]
Affiliated researcher
Simulated single molecule microscopy with SMeagol.
Lindén M, Ćurić V, Boucharin A, Fange D, Elf J
Bioinformatics 32 (15) 2394-2395 [2016-08-01; online 2016-03-04]
Affiliated researcher
Profilin connects actin assembly with microtubule dynamics.
Nejedla M, Sadi S, Sulimenko V, ..., Aspenström P, Karlsson R
Mol. Biol. Cell 27 (15) 2381-2393 [2016-08-01; online 2016-06-15]
Affiliated researcher
Adaptation to different types of stress converge on mitochondrial metabolism.
Lahtvee PJ, Kumar R, Hallström BM, Nielsen J
Mol. Biol. Cell 27 (15) 2505-2514 [2016-08-01; online 2016-06-15]
Affiliated researcher
Tuning fresh: radiation through rewiring of central metabolism in streamlined bacteria.
Eiler A, Mondav R, Sinclair L, ..., Woyke T, Bertilsson S
ISME J 10 (8) 1902-1914 [2016-08-00; online 2016-01-19]
Affiliated researcher
SATB2 is expressed in Merkel cell carcinoma.
Fukuhara M, Agnarsdóttir M, Edqvist PH, Coter A, Ponten F
Arch. Dermatol. Res. 308 (6) 449-454 [2016-08-00; online 2016-06-04]
Affiliated researcher
Otopalatodigital spectrum disorders: refinement of the phenotypic and mutational spectrum.
Moutton S, Fergelot P, Naudion S, ..., Goizet C, Coupry I
J. Hum. Genet. 61 (8) 693-699 [2016-08-00; online 2016-05-19]
Affiliated researcher
Initial hyperinsulinemia and subsequent β-cell dysfunction is associated with elevated palmitate levels.
Staaf J, Ubhayasekera SJ, Sargsyan E, ..., Forslund A, Bergsten P
Pediatr. Res. 80 (2) 267-274 [2016-08-00; online 2016-04-11]
Affiliated researcher
Impact of ocean acidification on antimicrobial activity in gills of the blue mussel (Mytilus edulis).
Hernroth B, Baden S, Tassidis H, ..., Bergström Lind S, Bergquist J
Fish Shellfish Immunol. 55 (-) 452-459 [2016-08-00; online 2016-06-08]
Affiliated researcher
Evidence for genetic regulation of the human parieto-occipital 10-Hz rhythmic activity.
Salmela E, Renvall H, Kujala J, ..., Salmelin R, Kere J
Eur. J. Neurosci. 44 (3) 1963-1971 [2016-08-00; online 2016-07-04]
Affiliated researcher
Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors.
Sutton LA, Young E, Baliakas P, ..., Rosenquist R, ERIC, the European Research Initiative on CLL
Haematologica 101 (8) 959-967 [2016-08-00; online 2016-05-19]
Affiliated researcher
Coordinated disassembly of the divisome complex in Escherichia coli.
Söderström B, Mirzadeh K, Toddo S, ..., Skoglund U, Daley DO
Mol. Microbiol. 101 (3) 425-438 [2016-08-00; online 2016-05-23]
Affiliated researcher
Acoustic micro-vortexing of fluids, particles and cells in disposable microfluidic chips.
Iranmanesh I, Ohlin M, Ramachandraiah H, ..., Russom A, Wiklund M
Biomed Microdevices 18 (4) 71 [2016-08-00; online 2016-07-23]
Affiliated researcher
A Longitudinal Follow-up of Autoimmune Polyendocrine Syndrome Type 1.
Bruserud Ø, Oftedal BE, Landegren N, ..., Wolff AB, Husebye ES
J. Clin. Endocrinol. Metab. 101 (8) 2975-2983 [2016-08-00; online 2016-06-02]
Affiliated researcher
The Synchronization of Replication and Division Cycles in Individual E. coli Cells.
Wallden M, Fange D, Lundius EG, Baltekin Ö, Elf J
Cell 166 (3) 729-739 [2016-07-28; online 2016-07-30]
Affiliated researcher
Human cytomegalovirus may promote tumour progression by upregulating arginase-2.
Costa H, Xu X, Overbeek G, ..., Söderberg-Naucler C, Yaiw KC
Oncotarget 7 (30) 47221-47231 [2016-07-26; online 2016-07-01]
Affiliated researcher
Identification of meat products by shotgun spectral matching.
Ohana D, Dalebout H, Marissen RJ, ..., Deelder AM, Palmblad M
Food Chem 203 (-) 28-34 [2016-07-15; online 2016-02-02]
Affiliated researcher
Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification.
Reischauer S, Stone OA, Villasenor A, ..., Andersson O, Stainier DY
Nature 535 (7611) 294-298 [2016-07-14; online 2016-07-15]
Affiliated researcher
Human serum-derived protein removes the need for coating in defined human pluripotent stem cell culture.
Pijuan-Galitó S, Tamm C, Schuster J, ..., Merry CL, Annerén C
Nat Commun 7 (-) 12170 [2016-07-13; online 2016-07-13]
Affiliated researcher
Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer.
Jarvis D, Mitchell JS, Law PJ, ..., Tomlinson IP, Houlston RS
Br. J. Cancer 115 (2) 266-272 [2016-07-12; online 2016-06-23]
Affiliated researcher
Identifying Genetic Signatures of Natural Selection Using Pooled Population Sequencing in Picea abies.
Chen J, Källman T, Ma XF, ..., Morgante M, Lascoux M
G3 6 (7) 1979-1989 [2016-07-07; online 2016-07-07]
Affiliated researcher
Exome sequencing in pooled DNA samples to identify maternal pre-eclampsia risk variants.
Kaartokallio T, Wang J, Heinonen S, ..., Kere J, Laivuori H
Sci Rep 6 (-) 29085 [2016-07-07; online 2016-07-07]
Affiliated researcher
Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer.
Mezheyeuski A, Bradic Lindh M, Guren TK, ..., Sorbye H, Östman A
Oncotarget 7 (27) 41948-41958 [2016-07-05; online 2016-06-02]
Affiliated researcher
Estrogen receptor beta reduces colon cancer metastasis through a novel miR-205 - PROX1 mechanism.
Nguyen-Vu T, Wang J, Mesmar F, ..., Bondesson M, Williams C
Oncotarget 7 (27) 42159-42171 [2016-07-05; online 2016-06-11]
Affiliated researcher
Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome.
Harris VM, Sharma R, Cavett J, ..., Sivils KL, Scofield RH
Clin. Immunol. 168 (-) 25-29 [2016-07-00; online 2016-04-22]
Affiliated researcher
Genome-wide selective sweeps and gene-specific sweeps in natural bacterial populations.
Bendall ML, Stevens SL, Chan LK, ..., McMahon KD, Malmstrom RR
ISME J 10 (7) 1589-1601 [2016-07-00; online 2016-01-08]
Affiliated researcher
Corticolimbic anatomical characteristics predetermine risk for chronic pain.
Vachon-Presseau E, Tétreault P, Petre B, ..., Baliki MN, Apkarian AV
Brain 139 (Pt 7) 1958-1970 [2016-07-00; online 2016-05-05]
Affiliated researcher Erika Comasco SciLifeLab Fellow
Constraints on methane oxidation in ice-covered boreal lakes
Denfeld BA, Ricão Canelhas M, Weyhenmeyer GA, ..., Eiler A, Bastviken D
J. Geophys. Res. Biogeosci. 121 (7) 1924-1933 [2016-07-00; online 2016-07-22]
Affiliated researcher
Chronic kidney disease and 10-year risk of cardiovascular death.
Holzmann MJ, Carlsson AC, Hammar N, ..., Wändell P, Ärnlöv J
Eur J Prev Cardiol 23 (11) 1187-1194 [2016-07-00; online 2015-11-05]
Affiliated researcher
Antagonists of IGF:Vitronectin Interactions Inhibit IGF-I-Induced Breast Cancer Cell Functions.
Kashyap AS, Shooter GK, Shokoohmand A, ..., Upton Z, Hollier BG
Mol. Cancer Ther. 15 (7) 1602-1613 [2016-07-00; online 2016-05-09]
Affiliated researcher
A draft fur seal genome provides insights into factors affecting SNP validation and how to mitigate them.
Humble E, Martinez-Barrio A, Forcada J, ..., Wolf JB, Hoffman JI
Mol Ecol Resour 16 (4) 909-921 [2016-07-00; online 2016-01-20]
Affiliated researcher
Heparanase expression upregulates platelet adhesion activity and thrombogenicity.
Cui H, Tan YX, Österholm C, ..., Vlodavsky I, Li JP
Oncotarget 7 (26) 39486-39496 [2016-06-28; online 2016-10-26]
Affiliated researcher
Conformational diversity and enantioconvergence in potato epoxide hydrolase 1.
Bauer P, Carlsson ÅJ, Amrein BA, ..., Widersten M, Kamerlin SC
Org. Biomol. Chem. 14 (24) 5639-5651 [2016-06-28; online 2016-04-06]
Affiliated researcher
Cryptosporidium as a testbed for single cell genome characterization of unicellular eukaryotes.
Troell K, Hallström B, Divne AM, ..., Beser J, Bertilsson S
BMC Genomics 17 (-) 471 [2016-06-23; online 2016-06-23]
Affiliated researcher
Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations.
Wu C, de Miranda NF, Chen L, ..., Sander B, Pan-Hammarström Q
Oncotarget 7 (25) 38180-38190 [2016-06-21; online 2016-10-23]
Affiliated researcher
iGEMS: an integrated model for identification of alternative exon usage events.
Sood S, Szkop KJ, Nakhuda A, ..., Larsson O, Timmons JA
Nucleic Acids Res. 44 (11) e109 [2016-06-20; online 2016-04-19]
Affiliated researcher
Identification of Cancer Related Genes Using a Comprehensive Map of Human Gene Expression.
Torrente A, Lukk M, Xue V, ..., Rung J, Brazma A
PLoS ONE 11 (6) e0157484 [2016-06-20; online 2016-06-20]
Affiliated researcher
Effects of Fluoxetine on Human Embryo Development.
Kaihola H, Yaldir FG, Hreinsson J, ..., Åkerud H, Sundström-Poromaa I
Front. Cell. Neurosci. 10 (-) 160 [2016-06-16; online 2016-06-16]
Affiliated researcher
Read-based phasing of related individuals.
Garg S, Martin M, Marschall T
Bioinformatics 32 (12) i234-i242 [2016-06-15; online 2016-06-17]
Affiliated researcher
Protein Z: A putative novel biomarker for early detection of ovarian cancer.
Russell MR, Walker MJ, Williamson AJ, ..., Jacobs I, Graham RL
Int. J. Cancer 138 (12) 2984-2992 [2016-06-15; online 2016-02-19]
Affiliated researcher
The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia.
Papakonstantinou N, Ntoufa S, Chartomatsidou E, ..., Rosenquist R, Stamatopoulos K
Oncotarget 7 (24) 35946-35959 [2016-06-14; online 2016-05-19]
Affiliated researcher
Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation.
Watanabe Y, Papoutsoglou P, Maturi V, ..., Heldin CH, Moustakas A
J. Biol. Chem. 291 (24) 12706-12723 [2016-06-10; online 2016-04-21]
Affiliated researcher
Reciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation.
Conti L, Renhorn J, Gabrielsson A, ..., Lindahl E, Elinder F
Sci Rep 6 (-) 27562 [2016-06-09; online 2016-06-09]
Affiliated researcher
Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy.
Steshenko O, Andrade DM, Honigmann A, ..., Simons M, Eggeling C
Biophys. J. 110 (11) 2441-2450 [2016-06-07; online 2016-06-09]
Erdinc Sezgin SciLifeLab Fellow
Recommendations on e-infrastructures for next-generation sequencing.
Spjuth O, Bongcam-Rudloff E, Dahlberg J, ..., Vezzi F, Korpelainen E
Gigascience 5 (-) 26 [2016-06-07; online 2016-06-07]
Affiliated researcher
Genetic Basis for Red Coloration in Birds.
Lopes RJ, Johnson JD, Toomey MB, ..., Corbo JC, Carneiro M
Curr. Biol. 26 (11) 1427-1434 [2016-06-06; online 2016-05-19]
Affiliated researcher
A comparative evaluation of data-merging and meta-analysis methods for reconstructing gene-gene interactions.
Lagani V, Karozou AD, Gomez-Cabrero D, Silberberg G, Tsamardinos I
BMC Bioinformatics 17 Suppl 5 (-) 194 [2016-06-06; online 2016-06-06]
Affiliated researcher
Elevated levels of FN1 and CCL2 in bronchoalveolar lavage fluid from sarcoidosis patients.
Hamsten C, Wiklundh E, Grönlund H, ..., Grunewald J, Häggmark-Månberg A
Respir. Res. 17 (1) 69 [2016-06-04; online 2016-06-04]
Affiliated researcher
TT-seq maps the human transient transcriptome.
Schwalb B, Michel M, Zacher B, ..., Gagneur J, Cramer P
Science 352 (6290) 1225-1228 [2016-06-03; online 2016-06-04]
Affiliated researcher
Prognostic impact of epigenetic classification in chronic lymphocytic leukemia: The case of subset #2.
Bhoi S, Ljungström V, Baliakas P, ..., Rosenquist R, Mansouri L
Epigenetics 11 (6) 449-455 [2016-06-02; online 2016-04-29]
Affiliated researcher
Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease.
Dumanski JP, Lambert JC, Rasi C, ..., Lind L, Forsberg LA
Am. J. Hum. Genet. 98 (6) 1208-1219 [2016-06-02; online 2016-05-23]
Affiliated researcher
Identification of Multiple Loci Associated with Social Parasitism in Honeybees.
Wallberg A, Pirk CW, Allsopp MH, Webster MT
PLoS Genet 12 (6) e1006097 [2016-06-00; online 2016-06-09]
Affiliated researcher
High density of REC8 constrains sister chromatid axes and prevents illegitimate synaptonemal complex formation.
Agostinho A, Manneberg O, van Schendel R, ..., Brismar H, Höög C
EMBO Rep. 17 (6) 901-913 [2016-06-00; online 2016-05-11]
Affiliated researcher
GPR44 is a pancreatic protein restricted to the human beta cell.
Hellström-Lindahl E, Danielsson A, Ponten F, ..., Johansson L, Eriksson O
Acta Diabetol 53 (3) 413-421 [2016-06-00; online 2015-10-14]
Affiliated researcher Olof Eriksson SciLifeLab Fellow
Epigenome-wide DNA methylation patterns associated with fatigue in primary Sjögren's syndrome.
Brække Norheim K, Imgenberg-Kreuz J, Jonsdottir K, ..., Nordmark G, Omdal R
Rheumatology (Oxford) 55 (6) 1074-1082 [2016-06-00; online 2016-03-10]
Affiliated researcher
Detection of Biomarkers with Solid-Phase Proximity Ligation Assay in Patients with Colorectal Cancer.
Ghanipour L, Darmanis S, Landegren U, ..., Påhlman L, Birgisson H
Transl Oncol 9 (3) 251-255 [2016-06-00; online 2016-06-09]
Affiliated researcher
Affinity proteomics discovers decreased levels of AMFR in plasma from Osteoporosis patients.
Qundos U, Drobin K, Mattsson C, ..., Michaëlsson K, Schwenk JM
Proteomics Clin Appl 10 (6) 681-690 [2016-06-00; online 2015-04-21]
Affiliated researcher
Variants within the SP110 nuclear body protein modify risk of canine degenerative myelopathy.
Ivansson EL, Megquier K, Kozyrev SV, ..., Coates JR, Lindblad-Toh K
Proc. Natl. Acad. Sci. U.S.A. 113 (22) E3091-E3100 [2016-05-31; online 2016-05-16]
Affiliated researcher
Genome-culture coevolution promotes rapid divergence of killer whale ecotypes.
Foote AD, Vijay N, Ávila-Arcos MC, ..., Gilbert MT, Wolf JB
Nat Commun 7 (-) 11693 [2016-05-31; online 2016-05-31]
Affiliated researcher
New technologies for DNA analysis--a review of the READNA Project.
McGinn S, Bauer D, Brefort T, ..., Willcocks JP, Gut IG
N Biotechnol 33 (3) 311-330 [2016-05-25; online 2015-10-26]
Affiliated researcher
Minimal selective concentrations of tetracycline in complex aquatic bacterial biofilms.
Lundström SV, Östman M, Bengtsson-Palme J, ..., Flach CF, Larsson DGJ
Sci. Total Environ. 553 (-) 587-595 [2016-05-15; online 2016-03-22]
DDLS Fellow Johan Bengtsson-Palme
The genetic basis for ecological adaptation of the Atlantic herring revealed by genome sequencing.
Martinez Barrio A, Lamichhaney S, Fan G, ..., Xu X, Andersson L
Elife 5 (-) - [2016-05-03; online 2016-05-03]
Affiliated researcher
Standardized benchmarking in the quest for orthologs.
Altenhoff AM, Boeckmann B, Capella-Gutierrez S, ..., Sonnhammer E, Dessimoz C
Nat. Methods 13 (5) 425-430 [2016-05-00; online 2016-04-04]
Affiliated researcher
Selection of optimal chelator improves the contrast of GRPR imaging using bombesin analogue RM26.
Mitran B, Varasteh Z, Selvaraju RK, ..., Rosenström U, Orlova A
Int. J. Oncol. 48 (5) 2124-2134 [2016-05-00; online 2016-03-09]
Affiliated researcher
Increased diversification rates follow shifts to bisexuality in liverworts.
Laenen B, Machac A, Gradstein SR, ..., Shaw AJ, Vanderpoorten A
New Phytol. 210 (3) 1121-1129 [2016-05-00; online 2016-02-01]
Affiliated researcher
Genome-Wide Analysis Identifies Germ-Line Risk Factors Associated with Canine Mammary Tumours.
Melin M, Rivera P, Arendt M, ..., Rönnberg H, Lindblad-Toh K
PLoS Genet 12 (5) e1006029 [2016-05-00; online 2016-05-09]
Affiliated researcher
Antigen arrays for profiling autoantibody repertoires.
Ayoglu B, Schwenk JM, Nilsson P
Bioanalysis 8 (10) 1105-1126 [2016-05-00; online 2016-04-21]
Affiliated researcher
An Improved microRNA Annotation of the Canine Genome.
Penso-Dolfin L, Swofford R, Johnson J, ..., Moxon S, Di Palma F
PLoS ONE 11 (4) e0153453 [2016-04-27; online 2016-04-27]
Affiliated researcher
Elevated Levels of SOX10 in Serum from Vitiligo and Melanoma Patients, Analyzed by Proximity Ligation Assay.
Blokzijl A, Chen LE, Gustafsdottir SM, ..., Kamali-Moghaddam M, Hedstrand H
PLoS ONE 11 (4) e0154214 [2016-04-25; online 2016-04-25]
Affiliated researcher
Effects of warming on a Mediterranean phytoplankton community
Pulina S, Brutemark A, Suikkanen S, ..., Sechi N, Lugliè A
Web Ecol. 16 (1) 89-92 [2016-04-22; online 2016-04-22]
Affiliated researcher
A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors.
Ruiz S, Mayor-Ruiz C, Lafarga V, ..., Ortega S, Fernandez-Capetillo O
Mol. Cell 62 (2) 307-313 [2016-04-21; online 2016-04-07]
Affiliated researcher
Improved topology prediction using the terminal hydrophobic helices rule.
Peters C, Tsirigos KD, Shu N, Elofsson A
Bioinformatics 32 (8) 1158-1162 [2016-04-15; online 2015-12-07]
Affiliated researcher
Hypoxic Signaling and the Cellular Redox Tumor Environment Determine Sensitivity to MTH1 Inhibition.
Bräutigam L, Pudelko L, Jemth AS, ..., Stenmark P, Helleday T
Cancer Res. 76 (8) 2366-2375 [2016-04-15; online 2016-02-09]
Affiliated researcher
RING finger protein 31 promotes p53 degradation in breast cancer cells.
Zhu J, Zhao C, Zhuang T, ..., Strömblad S, Dahlman-Wright K
Oncogene 35 (15) 1955-1964 [2016-04-14; online 2015-07-06]
Affiliated researcher
Microchip Screening Platform for Single Cell Assessment of NK Cell Cytotoxicity.
Guldevall K, Brandt L, Forslund E, ..., Uhlin M, Önfelt B
Front Immunol 7 (-) 119 [2016-04-05; online 2016-04-05]
Affiliated researcher
mTORC1 and CK2 coordinate ternary and eIF4F complex assembly.
Gandin V, Masvidal L, Cargnello M, ..., Larsson O, Topisirovic I
Nat Commun 7 (-) 11127 [2016-04-04; online 2016-04-04]
Affiliated researcher
3D Bioprinting of Tissue/Organ Models.
Pati F, Gantelius J, Svahn HA
Angew. Chem. Int. Ed. Engl. 55 (15) 4650-4665 [2016-04-04; online 2016-02-19]
Affiliated researcher
Signals and Receptors.
Heldin CH, Lu B, Evans R, Gutkind JS
Cold Spring Harbor Perspectives in Biology 8 (4) a005900 [2016-04-01; online 2016-04-01]
Affiliated researcher
Na+-K+-ATPase, a new class of plasma membrane receptors.
Aperia A, Akkuratov EE, Fontana JM, Brismar H
Am. J. Physiol., Cell Physiol. 310 (7) C491-C495 [2016-04-01; online 2016-01-20]
Affiliated researcher
Genome-wide association and Mendelian randomization study of NT-proBNP in patients with acute coronary syndrome.
Johansson Å, Eriksson N, Lindholm D, ..., Wallentin L, PLATO Investigators
Hum. Mol. Genet. 25 (7) 1447-1456 [2016-04-01; online 2016-01-21]
Affiliated researcher
CopyNumber450kCancer: baseline correction for accurate copy number calling from the 450k methylation array.
Marzouka NA, Nordlund J, Bäcklin CL, ..., Syvänen AC, Carlsson Almlöf J
Bioinformatics 32 (7) 1080-1082 [2016-04-01; online 2015-11-09]
Affiliated researcher
USP7 is a SUMO deubiquitinase essential for DNA replication.
Lecona E, Rodriguez-Acebes S, Specks J, ..., Mendez J, Fernandez-Capetillo O
Nat. Struct. Mol. Biol. 23 (4) 270-277 [2016-04-00; online 2016-03-07]
Affiliated researcher
The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons.
Braasch I, Gehrke AR, Smith JJ, ..., Lindblad-Toh K, Postlethwait JH
Nat. Genet. 48 (4) 427-437 [2016-04-00; online 2016-03-07]
Affiliated researcher
The inflammatory inception of gallbladder cancer.
Espinoza JA, Bizama C, García P, ..., Koshiol J, Roa JC
Biochim. Biophys. Acta 1865 (2) 245-254 [2016-04-00; online 2016-03-12]
Affiliated researcher
The heterogeneity of human CD127(+) innate lymphoid cells revealed by single-cell RNA sequencing.
Björklund ÅK, Forkel M, Picelli S, ..., Sandberg R, Mjösberg J
Nat. Immunol. 17 (4) 451-460 [2016-04-00; online 2016-02-15]
Affiliated researcher
Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?
Baliakas P, Mattsson M, Stamatopoulos K, Rosenquist R
J. Intern. Med. 279 (4) 347-357 [2016-04-00; online 2015-12-28]
Affiliated researcher
NgR1: A Tunable Sensor Regulating Memory Formation, Synaptic, and Dendritic Plasticity.
Karlsson TE, Smedfors G, Brodin AT, ..., Brené S, Olson L
Cereb. Cortex 26 (4) 1804-1817 [2016-04-00; online 2016-02-02]
Affiliated researcher
Neuroproteomic profiling of human body fluids.
Häggmark A, Schwenk JM, Nilsson P
Proteomics Clin Appl 10 (4) 485-502 [2016-04-00; online 2015-10-12]
Affiliated researcher
Multiplexed protein profiling by sequential affinity capture.
Ayoglu B, Birgersson E, Mezger A, ..., Nilsson P, Schwenk JM
Proteomics 16 (8) 1251-1256 [2016-04-00; online 2016-03-31]
Affiliated researcher
Evolutionary Origins of Rhizarian Parasites.
Sierra R, Cañas-Duarte SJ, Burki F, ..., Arzul I, Pawlowski J
Mol. Biol. Evol. 33 (4) 980-983 [2016-04-00; online 2015-12-16]
Fabien Burki SciLifeLab Fellow
A multiple-phenotype imputation method for genetic studies.
Dahl A, Iotchkova V, Baud A, ..., Kranis A, Marchini J
Nat. Genet. 48 (4) 466-472 [2016-04-00; online 2016-02-22]
Affiliated researcher
A Facile Synthesis of NODASA-Functionalized Peptide
Naicker T, Albericio F, Dutta J, ..., Kruger H, Govender T
Synlett 27 (11) 1685-1688 [2016-03-30; online 2016-03-30]
Affiliated researcher
Trigger Factor Reduces the Force Exerted on the Nascent Chain by a Cotranslationally Folding Protein.
Nilsson OB, Müller-Lucks A, Kramer G, Bukau B, von Heijne G
J. Mol. Biol. 428 (6) 1356-1364 [2016-03-27; online 2016-02-18]
Affiliated researcher
VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread.
Li X, Padhan N, Sjöström EO, ..., Jansson L, Claesson-Welsh L
Nat Commun 7 (-) 11017 [2016-03-23; online 2016-03-23]
Affiliated researcher
System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis.
Pozniak Y, Balint-Lahat N, Rudolph JD, ..., Barshack I, Geiger T
Cell Systems 2 (3) 172-184 [2016-03-23; online 2016-03-03]
Affiliated researcher
On-Water Synthesis of Biaryl Sulfonyl Fluorides.
Chinthakindi PK, Kruger HG, Govender T, Naicker T, Arvidsson PI
J. Org. Chem. 81 (6) 2618-2623 [2016-03-18; online 2016-02-29]
Affiliated researcher
Biological insertion of computationally designed short transmembrane segments.
Baeza-Delgado C, von Heijne G, Marti-Renom MA, Mingarro I
Sci Rep 6 (-) 23397 [2016-03-18; online 2016-03-18]
Affiliated researcher
Use of Time-Resolved Fluorescence To Improve Sensitivity and Dynamic Range of Gel-Based Proteomics.
Sandberg A, Buschmann V, Kapusta P, Erdmann R, Wheelock ÅM
Anal. Chem. 88 (6) 3067-3074 [2016-03-15; online 2016-02-22]
Affiliated researcher
NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis.
Tervaniemi MH, Katayama S, Skoog T, ..., Kere J, Elomaa O
Sci Rep 6 (-) 22745 [2016-03-15; online 2016-03-15]
Affiliated researcher
Glycation Reactivity of a Quorum-Sensing Signaling Molecule.
Tsuchikama K, Gooyit M, Harris TL, ..., Kaufmann GF, Janda KD
Angew. Chem. Int. Ed. Engl. 55 (12) 4002-4006 [2016-03-14; online 2016-02-17]
Daniel Globisch SciLifeLab Fellow
Engineering Cellular Metabolism.
Nielsen J, Keasling JD
Cell 164 (6) 1185-1197 [2016-03-10; online 2016-03-12]
Affiliated researcher
Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease.
Khoonsari PE, Häggmark A, Lönnberg M, ..., Kultima K, Shevchenko G
PLoS ONE 11 (3) e0150672 [2016-03-07; online 2016-03-07]
Affiliated researcher
Fast, accurate, and lightweight analysis of BS-treated reads with ERNE 2.
Prezza N, Vezzi F, Käller M, Policriti A
BMC Bioinformatics 17 Suppl 4 (-) 69 [2016-03-02; online 2016-03-02]
Affiliated researcher
Cells release subpopulations of exosomes with distinct molecular and biological properties.
Willms E, Johansson HJ, Mäger I, ..., Wood MJ, Vader P
Sci Rep 6 (-) 22519 [2016-03-02; online 2016-03-02]
Affiliated researcher
Estrogen receptor beta as target for colorectal cancer prevention.
Williams C, DiLeo A, Niv Y, Gustafsson JÅ
Cancer Lett. 372 (1) 48-56 [2016-03-01; online 2015-12-18]
Affiliated researcher
The metabolic fingerprint of p,p'-DDE and HCB exposure in humans.
Salihovic S, Ganna A, Fall T, ..., Ingelsson E, Lind L
Environ Int 88 (-) 60-66 [2016-03-00; online 2015-12-22]
Affiliated researcher
T-cell receptor-HLA-DRB1 associations suggest specific antigens in pulmonary sarcoidosis.
Grunewald J, Kaiser Y, Ostadkarampour M, ..., Ronninger M, Eklund A
Eur. Respir. J. 47 (3) 898-909 [2016-03-00; online 2015-11-19]
Affiliated researcher
Small protein domains fold inside the ribosome exit tunnel.
Marino J, von Heijne G, Beckmann R
FEBS Lett. 590 (5) 655-660 [2016-03-00; online 2016-02-25]
Affiliated researcher
Second generation sequencing of microRNA in Human Bone Cells treated with Parathyroid Hormone or Dexamethasone.
Laxman N, Rubin CJ, Mallmin H, ..., Tellgren-Roth C, Kindmark A
Bone 84 (-) 181-188 [2016-03-00; online 2015-12-31]
Affiliated researcher
Rapid and straightforward transesterification of sulfonyl carbamates
Isaksson R, Kumpiņa I, Larhed M, Wannberg J
Tetrahedron Letters 57 (13) 1476-1478 [2016-03-00; online 2016-03-00]
Affiliated researcher
Oncogene-Induced Senescence in Pituitary Adenomas--an Immunohistochemical Study.
Manojlovic-Gacic E, Skender-Gazibara M, Popovic V, ..., Pontén F, Casar-Borota O
Endocr. Pathol. 27 (1) 1-11 [2016-03-00; online 2015-11-18]
Affiliated researcher
Normalization of circulating microRNA expression data obtained by quantitative real-time RT-PCR.
Marabita F, de Candia P, Torri A, ..., Abrignani S, Rossi RL
Brief. Bioinformatics 17 (2) 204-212 [2016-03-00; online 2015-08-03]
Affiliated researcher
Identification of novel genetic causes of Rett syndrome-like phenotypes.
Lopes F, Barbosa M, Ameur A, ..., Pinto D, Maciel P
J. Med. Genet. 53 (3) 190-199 [2016-03-00; online 2016-01-06]
Affiliated researcher
Geographical range in liverworts: does sex really matter?
Laenen B, Machac A, Gradstein SR, ..., Shaw J, Vanderpoorten A
J. Biogeogr. 43 (3) 627-635 [2016-03-00; online 2015-11-04]
Affiliated researcher
Gene expression signatures, pathways and networks in carotid atherosclerosis.
Perisic L, Aldi S, Sun Y, ..., Paulsson-Berne G, Hedin U
J. Intern. Med. 279 (3) 293-308 [2016-03-00; online 2015-11-30]
Affiliated researcher
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma.
Ambrogio C, Gómez-López G, Falcone M, ..., Santamaría D, Barbacid M
Nat. Med. 22 (3) 270-277 [2016-03-00; online 2016-02-08]
Affiliated researcher
Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients.
Kirchner H, Sinha I, Gao H, ..., Dahlman-Wright K, Zierath JR
Mol Metab 5 (3) 171-183 [2016-03-00; online 2016-01-02]
Affiliated researcher
Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations.
Ljungström V, Cortese D, Young E, ..., Sjöblom T, Rosenquist R
Blood 127 (8) 1007-1016 [2016-02-25; online 2015-12-16]
Affiliated researcher
Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Newman JA, Cooper CD, Roos AK, ..., Osman R, Gileadi O
PLoS ONE 11 (2) e0148762 [2016-02-24; online 2016-02-24]
Affiliated researcher
An Efficient Protecting-Group-Free Synthesis of Vinylic Sulfoximines via Horner–Wadsworth–Emmons Reaction
Naicker T, Arvidsson P, Chinthakindi P, ..., Govender T, Kruger H
Synlett 27 (09) 1423-1427 [2016-02-24; online 2016-02-24]
Affiliated researcher
Anoctamin 2 identified as an autoimmune target in multiple sclerosis.
Ayoglu B, Mitsios N, Kockum I, ..., Olsson T, Nilsson P
Proc. Natl. Acad. Sci. U.S.A. 113 (8) 2188-2193 [2016-02-23; online 2016-02-09]
Affiliated researcher
Stepwise nucleosome translocation by RSC remodeling complexes.
Harada BT, Hwang WL, Deindl S, ..., Bartholomew B, Zhuang X
Elife 5 (-) - [2016-02-19; online 2016-02-19]
SciLifeLab Fellow Sebastian Deindl
Genomic inference of the metabolism of cosmopolitan subsurface Archaea, Hadesarchaea.
Baker BJ, Saw JH, Lind AE, ..., Teske AP, Ettema TJ
Nat. Microbiol 1 (-) 16002 [2016-02-15; online 2016-02-15]
Affiliated researcher
Exome sequencing in one family with gastric- and rectal cancer.
Thutkawkorapin J, Picelli S, Kontham V, ..., Nilsson D, Lindblom A
BMC Genet. 17 (-) 41 [2016-02-13; online 2016-02-13]
Affiliated researcher
Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1.
Llona-Minguez S, Höglund A, Jacques SA, ..., Scobie M, Helleday T
J. Med. Chem. 59 (3) 1140-1148 [2016-02-11; online 2016-01-27]
Affiliated researcher
Systems Proteomics View of the Endogenous Human Claudin Protein Family.
Liu F, Koval M, Ranganathan S, ..., Kelleher NL, Baker MS
J. Proteome Res. 15 (2) 339-359 [2016-02-05; online 2016-01-12]
Affiliated researcher
Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1.
Landegren N, Sharon D, Freyhult E, ..., Snyder M, Kämpe O
Sci Rep 6 (-) 20104 [2016-02-01; online 2016-02-01]
Affiliated researcher
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
Lu Y, Day FR, Gustafsson S, ..., Kilpeläinen TO, Loos RJ
Nat Commun 7 (-) 10495 [2016-02-01; online 2016-02-01]
Affiliated researcher
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
Kilpeläinen TO, Carli JF, Skowronski AA, ..., Leibel RL, Loos RJ
Nat Commun 7 (-) 10494 [2016-02-01; online 2016-02-01]
Affiliated researcher
The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition.
Ölander M, Wiśniewski JR, Matsson P, Lundquist P, Artursson P
J Pharm Sci 105 (2) 817-827 [2016-02-00; online 2016-01-09]
Affiliated researcher
TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors.
Doorduijn EM, Sluijter M, Querido BJ, ..., van der Burg SH, van Hall T
J. Clin. Invest. 126 (2) 784-794 [2016-02-00; online 2016-01-19]
Affiliated researcher
Segmentation and Track-Analysis in Time-Lapse Imaging of Bacteria
Sadanandan SK, Baltekin O, Magnusson KEG, ..., Elf J, Wahlby C
IEEE J. Sel. Top. Signal Process. 10 (1) 174-184 [2016-02-00; online 2016-02-00]
Affiliated researcher
Oufti: an integrated software package for high-accuracy, high-throughput quantitative microscopy analysis.
Paintdakhi A, Parry B, Campos M, ..., Surovtsev I, Jacobs-Wagner C
Mol. Microbiol. 99 (4) 767-777 [2016-02-00; online 2015-12-18]
Affiliated researcher
Mechanisms of action of bone morphogenetic proteins in cancer.
Davis H, Raja E, Miyazono K, Tsubakihara Y, Moustakas A
Cytokine Growth Factor Rev. 27 (-) 81-92 [2016-02-00; online 2015-11-24]
Affiliated researcher
Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12.
Mäkinen N, Aavikko M, Heikkinen T, ..., Bützow R, Vahteristo P
PLoS Genet 12 (2) e1005850 [2016-02-00; online 2016-02-18]
Affiliated researcher
Decreased levels of stem cell factor in subjects with incident coronary events.
Wigren M, Rattik S, Hultman K, ..., Gonçalves I, Nilsson J
J. Intern. Med. 279 (2) 180-191 [2016-02-00; online 2015-10-14]
Affiliated researcher
Correlating chemical sensitivity and basal gene expression reveals mechanism of action.
Rees MG, Seashore-Ludlow B, Cheah JH, ..., Shamji AF, Schreiber SL
Nat. Chem. Biol. 12 (2) 109-116 [2016-02-00; online 2015-12-14]
Affiliated researcher
Computational Cancer Biology: An Evolutionary Perspective.
Beerenwinkel N, Greenman CD, Lagergren J
PLoS Comput Biol 12 (2) e1004717 [2016-02-00; online 2016-02-04]
Affiliated researcher
Complete Knockout of Endogenous Mdr1 ( Abcb1 ) in MDCK Cells by CRISPR-Cas9
Simoff I, Karlgren M, Backlund M, ..., Matsson P, Artursson P
Journal of Pharmaceutical Sciences 105 (2) 1017-1021 [2016-02-00; online 2016-02-00]
Affiliated researcher
Association between levels of pentraxin 3 and incidence of chronic kidney disease in the elderly.
Sjöberg B, Qureshi AR, Heimbürger O, ..., Bárány P, Ärnlöv J
J. Intern. Med. 279 (2) 173-179 [2016-02-00; online 2015-09-09]
Affiliated researcher
Recent advances in understanding Type 1 Diabetes.
Christoffersson G, Rodriguez-Calvo T, von Herrath M
F1000Res 5 (-) - [2016-01-27; online 2016-01-27]
Gustaf Christoffersson SciLifeLab Fellow
A survey of best practices for RNA-seq data analysis.
Conesa A, Madrigal P, Tarazona S, ..., Zhang X, Mortazavi A
Genome Biol. 17 (-) 13 [2016-01-26; online 2016-01-26]
Affiliated researcher
Exploration of Interfacial Hydration Networks of Target-Ligand Complexes.
Jeszenői N, Bálint M, Horváth I, van der Spoel D, Hetényi C
J Chem Inf Model 56 (1) 148-158 [2016-01-25; online 2016-01-08]
Affiliated researcher
Proadifen sensitizes resistant ovarian adenocarcinoma cells to cisplatin.
Jendželovský R, Jendželovská Z, Hiľovská L, ..., Mikeš J, Fedoročko P
Toxicol. Lett. 243 (-) 56-66 [2016-01-22; online 2015-12-22]
Affiliated researcher
Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation.
Bahram F, Hydbring P, Tronnersjö S, ..., Castell A, Larsson LG
Oncotarget 7 (3) 2837-2854 [2016-01-19; online 2015-12-25]
Affiliated researcher
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.
de Vries PS, Chasman DI, Sabater-Lleal M, ..., Strachan DP, Dehghan A
Hum. Mol. Genet. 25 (2) 358-370 [2016-01-15; online 2015-11-10]
Affiliated researcher
The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling.
Raja E, Tzavlaki K, Vuilleumier R, ..., Heldin CH, Moustakas A
Oncotarget 7 (2) 1120-1143 [2016-01-12; online 2015-12-25]
Affiliated researcher
Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells.
Darmanis S, Gallant CJ, Marinescu VD, ..., Westermark B, Landegren U
Cell Reports 14 (2) 380-389 [2016-01-12; online 2015-12-31]
Affiliated researcher
Influence of pre-existing inflammation on the outcome of acute coronary syndrome: a cross-sectional study.
Odeberg J, Freitag M, Forssell H, ..., Råstam L, Lindblad U
BMJ Open 6 (1) e009968 [2016-01-12; online 2016-01-12]
Affiliated researcher
Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis.
Bersani C, Huss M, Giacomello S, ..., Lui WO, Wiman KG
Oncotarget 7 (2) 1895-1911 [2016-01-12; online 2015-12-18]
Affiliated researcher
Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities.
Sanjiv K, Hagenkort A, Calderón-Montaño JM, ..., Altun M, Helleday T
Cell Reports 14 (2) 298-309 [2016-01-12; online 2015-12-31]
Affiliated researcher
Case definitions in Swedish register data to identify systemic lupus erythematosus.
Arkema EV, Jönsen A, Rönnblom L, ..., Sjöwall C, Simard JF
BMJ Open 6 (1) e007769 [2016-01-04; online 2016-01-04]
Affiliated researcher
CRISPRz: a database of zebrafish validated sgRNAs.
Varshney GK, Zhang S, Pei W, ..., Sood R, Burgess SM
Nucleic Acids Res. 44 (D1) D822-D826 [2016-01-04; online 2015-10-04]
Affiliated researcher
Antigen Selection Shapes the T-cell Repertoire in Chronic Lymphocytic Leukemia.
Vardi A, Agathangelidis A, Stalika E, ..., Sutton LA, Stamatopoulos K
Clin. Cancer Res. 22 (1) 167-174 [2016-01-01; online 2015-09-02]
Affiliated researcher
hTERT promoter methylation in pituitary adenomas.
Köchling M, Ewelt C, Fürtjes G, ..., Stummer W, Brokinkel B
Brain Tumor Pathol 33 (1) 27-34 [2016-01-00; online 2015-09-21]
Affiliated researcher
Protein Biomarkers for Insulin Resistance and Type 2 Diabetes Risk in Two Large Community Cohorts.
Nowak C, Sundström J, Gustafsson S, ..., Ingelsson E, Fall T
Diabetes 65 (1) 276-284 [2016-01-00; online 2015-09-29]
Affiliated researcher
Out of southern East Asia: the natural history of domestic dogs across the world.
Wang GD, Zhai W, Yang HC, ..., Savolainen P, Zhang YP
Cell Res. 26 (1) 21-33 [2016-01-00; online 2015-12-15]
Affiliated researcher
Mutations in FLVCR2 associated with Fowler syndrome and survival beyond infancy.
Kvarnung M, Taylan F, Nilsson D, ..., Nordgren A, Syk Lundberg E
Clin. Genet. 89 (1) 99-103 [2016-01-00; online 2015-03-04]
Affiliated researcher
Large-scale non-targeted metabolomic profiling in three human population-based studies
Ganna A, Fall T, Salihovic S, ..., Pawitan Y, Ingelsson E
Metabolomics 12 (1) - [2016-01-00; online 2015-11-07]
Affiliated researcher
Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells.
Stäubert C, Krakowsky R, Bhuiyan H, ..., Broom O, Nordström A
Med. Oncol. 33 (1) 6 [2016-01-00; online 2015-12-23]
Affiliated researcher
Genetic heterogeneity in rhabdomyosarcoma revealed by SNP array analysis.
Walther C, Mayrhofer M, Nilsson J, ..., Gisselsson D, Mertens F
Genes Chromosomes Cancer 55 (1) 3-15 [2016-01-00; online 2015-10-20]
Affiliated researcher
F11 is associated with recurrent VTE in women. A prospective cohort study.
Bruzelius M, Ljungqvist M, Bottai M, ..., Lärfars G, Odeberg J
Thromb. Haemost. 115 (2) 406-414 [2016-01-00; online 2015-10-01]
Affiliated researcher
A minimalistic microbial food web in an excavated deep subsurface clay rock.
Bagnoud A, de Bruijn I, Andersson AF, ..., Schwyn B, Bernier-Latmani R
FEMS Microbiol. Ecol. 92 (1) - [2016-01-00; online 2015-11-04]
Affiliated researcher
Organocatalyzed Mannich reactions on minocycline: Towards novel tetracycline antibiotics
CHIWUNZE TE, Azumah R, Ramtahal M, ..., Govender T, Naicker T
S.Afr.j.chem. 69 (-) - [2016-00-00; online 2016-00-00]
Affiliated researcher
Fractal Dimension versus Process Complexity
Joosten JJ, Soler-Toscano F, Zenil H
Advances in Mathematical Physics 2016 (-) 1-21 [2016-00-00; online 2016-00-00]
Affiliated researcher
Fast Zeta Transforms for Lattices with Few Irreducibles
Björklund A, Husfeldt T, Kaski P, ..., Nederlof J, Parviainen P
TALG ACM Trans. Algorithms 12 (1) 1-19 [2015-12-31; online 2015-12-31]
Affiliated researcher
Systematic hierarchical coarse-graining with the inverse Monte Carlo method.
Lyubartsev AP, Naômé A, Vercauteren DP, Laaksonen A
J Chem Phys 143 (24) 243120 [2015-12-28; online 2016-01-03]
Affiliated researcher
Evaluation of Intracellular Signaling Downstream Chimeric Antigen Receptors.
Karlsson H, Svensson E, Gigg C, ..., Dotti G, Loskog A
PLoS ONE 10 (12) e0144787 [2015-12-23; online 2015-12-23]
Affiliated researcher
The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling.
Habuka M, Fagerberg L, Hallström BM, ..., Yamamoto T, Uhlen M
PLoS ONE 10 (12) e0145301 [2015-12-22; online 2015-12-22]
Affiliated researcher
Exploring water as building bricks in enzyme engineering.
Hendil-Forssell P, Martinelle M, Syrén PO
Chem. Commun. (Camb.) 51 (97) 17221-17224 [2015-12-18; online 2015-10-02]
Affiliated researcher
Oligonucleotide gap-fill ligation for mutation detection and sequencing in situ.
Mignardi M, Mezger A, Qian X, ..., Larsson C, Nilsson M
Nucleic Acids Res. 43 (22) e151 [2015-12-15; online 2015-08-03]
Affiliated researcher
Metagenome-assembled genomes uncover a global brackish microbiome.
Hugerth LW, Larsson J, Alneberg J, ..., Pinhassi J, Andersson AF
Genome Biol. 16 (-) 279 [2015-12-14; online 2015-12-14]
Affiliated researcher DDLS Fellow Luisa Hugerth
High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes.
Dijksterhuis JP, Arthofer E, Marinescu VD, ..., Mulder J, Schulte G
Exp. Cell Res. 339 (2) 280-288 [2015-12-10; online 2015-10-25]
Affiliated researcher
cgmisc: enhanced genome-wide association analyses and visualization.
Kierczak M, Jabłońska J, Forsberg SK, ..., Carlborg Ö, Lindblad-Toh K
Bioinformatics 31 (23) 3830-3831 [2015-12-01; online 2015-08-06]
Affiliated researcher
Stratification of Hepatocellular Carcinoma Patients Based on Acetate Utilization.
Björnson E, Mukhopadhyay B, Asplund A, ..., Nielsen J, Mardinoglu A
Cell Reports 13 (9) 2014-2026 [2015-12-01; online 2015-11-19]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration.
Roberts TC, Johansson HJ, McClorey G, ..., El Andaloussi S, Wood MJ
Hum. Mol. Genet. 24 (23) 6756-6768 [2015-12-01; online 2015-09-18]
Affiliated researcher
Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity.
Hägg S, Ganna A, Van Der Laan SW, ..., Pawitan Y, Ingelsson E
Hum. Mol. Genet. 24 (23) 6849-6860 [2015-12-01; online 2015-09-16]
Affiliated researcher
Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy.
Gineste C, Hernandez A, Ivarsson N, ..., Wredenberg A, Westerblad H
Hum. Mol. Genet. 24 (23) 6580-6587 [2015-12-01; online 2015-09-14]
Affiliated researcher
ARResT/AssignSubsets: a novel application for robust subclassification of chronic lymphocytic leukemia based on B cell receptor IG stereotypy.
Bystry V, Agathangelidis A, Bikos V, ..., Darzentas N, European Research Initiative on CLL
Bioinformatics 31 (23) 3844-3846 [2015-12-01; online 2015-08-06]
Affiliated researcher
The Constrained Maximal Expression Level Owing to Haploidy Shapes Gene Content on the Mammalian X Chromosome.
Hurst LD, Ghanbarian AT, Forrest AR, FANTOM consortium , Huminiecki L
PLoS Biol. 13 (12) e1002315 [2015-12-00; online 2015-12-18]
Affiliated researcher
Phenotypic expansion of visceral myopathy associated with ACTG2 tandem base substitution.
Klar J, Raykova D, Gustafson E, ..., Wanders A, Dahl N
Eur. J. Hum. Genet. 23 (12) 1679-1683 [2015-12-00; online 2015-03-18]
Affiliated researcher
Gout and its comorbidities in the total population of Stockholm.
Wändell P, Carlsson AC, Ljunggren G
Prev Med 81 (-) 387-391 [2015-12-00; online 2015-10-21]
Affiliated researcher
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Gaulton KJ, Ferreira T, Lee Y, ..., Morris AP, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Nat. Genet. 47 (12) 1415-1425 [2015-12-00; online 2015-11-09]
Affiliated researcher
Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies.
Albrecht I, Wick C, Hallgren Å, ..., Kämpe O, Lundberg IE
J. Clin. Invest. 125 (12) 4612-4624 [2015-12-00; online 2015-11-09]
Affiliated researcher
Daily self-sampling for high-risk human papillomavirus (HR-HPV) testing.
Sanner K, Wikström I, Gustavsson I, ..., Gyllensten U, Olovsson M
J. Clin. Virol. 73 (-) 1-7 [2015-12-00; online 2015-10-08]
Affiliated researcher
Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides
Gosselin-Badaroudine P, Moreau A, Delemotte L, ..., Klein ML, Chahine M
Sci Rep 5 (1) - [2015-12-00; online 2015-07-23]
Lucie Delemotte SciLifeLab Fellow
Bacterial diversity along a 2600 km river continuum.
Savio D, Sinclair L, Ijaz UZ, ..., Farnleitner AH, Eiler A
Environ. Microbiol. 17 (12) 4994-5007 [2015-12-00; online 2015-06-11]
Affiliated researcher
Alteration by p11 of mGluR5 localization regulates depression-like behaviors.
Lee KW, Westin L, Kim J, ..., Kim Y, Greengard P
Mol. Psychiatry 20 (12) 1546-1556 [2015-12-00; online 2015-09-15]
Affiliated researcher
Amelanism in the corn snake is associated with the insertion of an LTR-retrotransposon in the OCA2 gene.
Saenko SV, Lamichhaney S, Martinez Barrio A, ..., Andersson L, Milinkovitch MC
Sci Rep 5 (-) 17118 [2015-11-24; online 2015-11-24]
Affiliated researcher
Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification.
Vanlandewijck M, Lebouvier T, Andaloussi Mäe M, ..., Keller A, Betsholtz C
PLoS ONE 10 (11) e0143407 [2015-11-23; online 2015-11-23]
Affiliated researcher
RNA sequencing uncovers antisense RNAs and novel small RNAs in Streptococcus pyogenes.
Le Rhun A, Beer YY, Reimegård J, Chylinski K, Charpentier E
RNA Biol 13 (2) 177-195 [2015-11-19; online 2015-11-19]
Affiliated researcher
Jagged 1 Rescues the Duchenne Muscular Dystrophy Phenotype.
Vieira NM, Elvers I, Alexander MS, ..., Kunkel LM, Zatz M
Cell 163 (5) 1204-1213 [2015-11-19; online 2015-11-12]
Affiliated researcher
NPM1 histone chaperone is upregulated in glioblastoma to promote cell survival and maintain nucleolar shape.
Holmberg Olausson K, Elsir T, Moazemi Goudarzi K, Nistér M, Lindström MS
Sci Rep 5 (-) 16495 [2015-11-12; online 2015-11-12]
Affiliated researcher
The 2015 super-resolution microscopy roadmap
Hell SW, Sahl SJ, Bates M, ..., Diaspro A, Cordes T
J. Phys. D: Appl. Phys. 48 (44) 443001 [2015-11-11; online 2015-10-15]
Ilaria Testa SciLifeLab Fellow
Immunocapture strategies in translational proteomics.
Fredolini C, Byström S, Pin E, ..., Nilsson P, Schwenk JM
Expert Rev Proteomics 13 (1) 83-98 [2015-11-11; online 2015-11-11]
Affiliated researcher
Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response.
Xing M, Wang X, Palmai-Pallag T, ..., Hickson ID, Ying S
Oncotarget 6 (35) 37638-37646 [2015-11-10; online 2015-09-29]
Affiliated researcher
Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26.
Kishita Y, Pajak A, Bolar NA, ..., Okazaki Y, Wedell A
Am. J. Hum. Genet. 97 (5) 761-768 [2015-11-05; online 2015-10-29]
Affiliated researcher
Castration radiosensitizes prostate cancer tissue by impairing DNA double-strand break repair.
Tarish FL, Schultz N, Tanoglidi A, ..., Granfors T, Helleday T
Sci Transl Med 7 (312) 312re11 [2015-11-04; online 2015-11-06]
Affiliated researcher
NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity.
Jacome A, Gutierrez-Martinez P, Schiavoni F, ..., Blasco MA, Fernandez-Capetillo O
EMBO J. 34 (21) 2604-2619 [2015-11-03; online 2015-10-06]
Affiliated researcher
The ketogenic diet compensates for AGC1 deficiency and improves myelination.
Dahlin M, Martin DA, Hedlund Z, ..., von Döbeln U, Wedell A
Epilepsia 56 (11) e176-e181 [2015-11-00; online 2015-09-24]
Affiliated researcher
The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling.
Zieba A, Sjöstedt E, Olovsson M, ..., Uhlen M, Ponten F
OMICS 19 (11) 659-668 [2015-11-00; online 2015-10-21]
Affiliated researcher
Slow degradation in phagocytic astrocytes can be enhanced by lysosomal acidification.
Lööv C, Mitchell CH, Simonsson M, Erlandsson A
Glia 63 (11) 1997-2009 [2015-11-00; online 2015-06-12]
Affiliated researcher
Single-cell genomics of a rare environmental alphaproteobacterium provides unique insights into Rickettsiaceae evolution.
Martijn J, Schulz F, Zaremba-Niedzwiedzka K, ..., Guy L, Ettema TJ
ISME J 9 (11) 2373-2385 [2015-11-00; online 2015-04-07]
Affiliated researcher
Single-Molecule Sequencing Reveals Estrogen-Regulated Clinically Relevant lncRNAs in Breast Cancer.
Jonsson P, Coarfa C, Mesmar F, ..., Gunaratne PH, Williams C
Mol. Endocrinol. 29 (11) 1634-1645 [2015-11-00; online 2015-10-01]
Affiliated researcher
Rescue of primary ubiquinone deficiency due to a novel COQ7 defect using 2,4-dihydroxybensoic acid.
Freyer C, Stranneheim H, Naess K, ..., Wredenberg A, Wedell A
J. Med. Genet. 52 (11) 779-783 [2015-11-00; online 2015-06-17]
Affiliated researcher
Proteomic Profiling of Detergent Resistant Membranes (Lipid Rafts) of Prostasomes.
Dubois L, Ronquist KK, Ek B, Ronquist G, Larsson A
Mol. Cell Proteomics 14 (11) 3015-3022 [2015-11-00; online 2015-08-13]
Affiliated researcher
Population genetic differentiation of height and body mass index across Europe.
Robinson MR, Hemani G, Medina-Gomez C, ..., Yang J, Visscher PM
Nat. Genet. 47 (11) 1357-1362 [2015-11-00; online 2015-09-14]
Affiliated researcher
Mutation in CEP63 co-segregating with developmental dyslexia in a Swedish family.
Einarsdottir E, Svensson I, Darki F, ..., Kere J, Matsson H
Hum. Genet. 134 (11-12) 1239-1248 [2015-11-00; online 2015-09-23]
Affiliated researcher
Larger aggregates of mutant seipin in Celia's Encephalopathy, a new protein misfolding neurodegenerative disease.
Ruiz-Riquelme A, Sánchez-Iglesias S, Rábano A, ..., Araújo-Vilar D, Requena JR
Neurobiol. Dis. 83 (-) 44-53 [2015-11-00; online 2015-08-15]
Affiliated researcher
Integrating Sequence Evolution into Probabilistic Orthology Analysis.
Ullah I, Sjöstrand J, Andersson P, Sennblad B, Lagergren J
Syst. Biol. 64 (6) 969-982 [2015-11-00; online 2015-06-30]
Affiliated researcher
In situ forming interpenetrating hydrogels of hyaluronic acid hybridized with iron oxide nanoparticles.
Kheirabadi M, Shi L, Bagheri R, ..., Hilborn J, Ossipov DA
Biomater Sci 3 (11) 1466-1474 [2015-11-00; online 2015-08-08]
Affiliated researcher
Impact of sludge deposition on biodiversity.
Manzetti S, van der Spoel D
Ecotoxicology 24 (9) 1799-1814 [2015-11-00; online 2015-08-30]
Affiliated researcher
HaloPlex Targeted Resequencing for Mutation Detection in Clinical Formalin-Fixed, Paraffin-Embedded Tumor Samples.
Moens LN, Falk-Sörqvist E, Ljungström V, ..., Nilsson M, Botling J
J Mol Diagn 17 (6) 729-739 [2015-11-00; online 2015-09-03]
Affiliated researcher
Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background.
Elvers I, Turner-Maier J, Swofford R, ..., Lindblad-Toh K, Alföldi J
Genome Res. 25 (11) 1634-1645 [2015-11-00; online 2015-09-16]
Affiliated researcher
Early Exposure to Dogs and Farm Animals and the Risk of Childhood Asthma.
Fall T, Lundholm C, Örtqvist AK, ..., Ingelsson E, Almqvist C
JAMA Pediatr 169 (11) e153219 [2015-11-00; online 2015-11-02]
Affiliated researcher
Assessing the consistency of public human tissue RNA-seq data sets.
Danielsson F, James T, Gomez-Cabrero D, Huss M
Brief. Bioinformatics 16 (6) 941-949 [2015-11-00; online 2015-03-30]
Affiliated researcher
Identification of proteins highly expressed in uterine fluid from mice with hydrometra.
Antonson P, Nalvarte I, Varshney M, ..., Gustafsson JÅ, Dahlman-Wright K
Biochem. Biophys. Res. Commun. 466 (4) 650-655 [2015-10-30; online 2015-09-21]
Affiliated researcher
Crosstalk between Hippo and TGFβ: Subcellular Localization of YAP/TAZ/Smad Complexes.
Grannas K, Arngården L, Lönn P, ..., Zieba A, Söderberg O
J. Mol. Biol. 427 (21) 3407-3415 [2015-10-23; online 2015-05-01]
Affiliated researcher
The effect of N-methylation of amino acids (Ac-X-OMe) on solubility and conformation: a DFT study.
Md Abdur Rauf S, Arvidsson PI, Albericio F, ..., Kruger HG, Honarparvar B
Org. Biomol. Chem. 13 (39) 9993-10006 [2015-10-21; online 2015-08-21]
Affiliated researcher
Structure-activity relationships for lipoprotein lipase agonists that lower plasma triglycerides in vivo.
Caraballo R, Larsson M, Nilsson SK, ..., Enquist PA, Elofsson M
Eur J Med Chem 103 (-) 191-209 [2015-10-20; online 2015-09-02]
Affiliated researcher
Induction of USP17 by combining BET and HDAC inhibitors in breast cancer cells.
Borbely G, Haldosen LA, Dahlman-Wright K, Zhao C
Oncotarget 6 (32) 33623-33635 [2015-10-20; online 2015-09-18]
Affiliated researcher
Controlled Lateral Positioning of Microparticles Inside Droplets Using Acoustophoresis.
Fornell A, Nilsson J, Jonsson L, ..., Joensson HN, Tenje M
Anal. Chem. 87 (20) 10521-10526 [2015-10-20; online 2015-10-09]
Affiliated researcher
Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor.
Griese JJ, Kositzki R, Schrapers P, ..., Haumann M, Högbom M
J. Biol. Chem. 290 (42) 25254-25272 [2015-10-16; online 2015-08-31]
Affiliated researcher
Domestication Effects on Stress Induced Steroid Secretion and Adrenal Gene Expression in Chickens.
Fallahsharoudi A, de Kock N, Johnsson M, ..., Wright D, Jensen P
Sci Rep 5 (-) 15345 [2015-10-16; online 2015-10-16]
Affiliated researcher
Role of the AMP kinase in cytokine-induced human EndoC-βH1 cell death.
Fred RG, Kappe C, Ameur A, ..., Scharfmann R, Welsh N
Mol. Cell. Endocrinol. 414 (-) 53-63 [2015-10-15; online 2015-07-26]
Affiliated researcher
A straightforward approach for gated STED-FCS to investigate lipid membrane dynamics.
Clausen MP, Sezgin E, Bernardino de la Serna J, ..., Lagerholm BC, Eggeling C
Methods 88 (-) 67-75 [2015-10-15; online 2015-06-27]
Erdinc Sezgin SciLifeLab Fellow
Mutation in NRAS in familial Noonan syndrome--case report and review of the literature.
Ekvall S, Wilbe M, Dahlgren J, ..., Annerén G, Bondeson ML
BMC Med. Genet. 16 (-) 95 [2015-10-14; online 2015-10-14]
Affiliated researcher
The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation.
Gustafsson Sheppard N, Jarl L, Mahadessian D, ..., Jain M, Nilsson R
Sci Rep 5 (-) 15029 [2015-10-13; online 2015-10-13]
Affiliated researcher
The alternative splicing factor Nova2 regulates vascular development and lumen formation.
Giampietro C, Deflorian G, Gallo S, ..., Dejana E, Ghigna C
Nat Commun 6 (-) 8479 [2015-10-08; online 2015-10-08]
Affiliated researcher
Gene-pseudogene evolution: a probabilistic approach.
Mahmudi O, Sennblad B, Arvestad L, Nowick K, Lagergren J
BMC Genomics 16 Suppl 10 (-) S12 [2015-10-02; online 2015-10-02]
Affiliated researcher
Expanding the Catalytic Triad in Epoxide Hydrolases and Related Enzymes.
Amrein BA, Bauer P, Duarte F, ..., Widersten M, Kamerlin SC
ACS Catal 5 (10) 5702-5713 [2015-10-02; online 2015-08-17]
Affiliated researcher
Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair.
Xie S, Mortusewicz O, Ma HT, ..., Helleday T, Qian C
Mol. Cell 60 (1) 163-176 [2015-10-01; online 2015-09-03]
Affiliated researcher
Homozygous loss-of-function variants in European cosmopolitan and isolate populations.
Kaiser VB, Svinti V, Prendergast JG, ..., Semple CA, Wilson JF
Hum. Mol. Genet. 24 (19) 5464-5474 [2015-10-01; online 2015-07-14]
Affiliated researcher
The effects of age and gender on plasma levels of 63 cytokines.
Larsson A, Carlsson L, Gordh T, ..., Thulin M, Kamali-Moghaddam M
J. Immunol. Methods 425 (-) 58-61 [2015-10-00; online 2015-06-14]
Affiliated researcher
The cyanobacterium Mastigocladus fulfills the nitrogen demand of a terrestrial hot spring microbial mat.
Estrella Alcamán M, Fernandez C, Delgado A, Bergman B, Díez B
ISME J 9 (10) 2290-2303 [2015-10-00; online 2015-07-31]
Affiliated researcher
Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase.
Kleinschmidt TK, Haraldsson M, Basavarajappa D, ..., Lindbom L, Haeggström JZ
J. Pharmacol. Exp. Ther. 355 (1) 108-116 [2015-10-00; online 2015-08-17]
Affiliated researcher
RNA editing of non-coding RNA and its role in gene regulation.
Daniel C, Lagergren J, Öhman M
Biochimie 117 (-) 22-27 [2015-10-00; online 2015-06-05]
Affiliated researcher
Positive Modulation of the Glycine Receptor by Means of Glycine Receptor-Binding Aptamers.
Shalaly ND, Aneiros E, Blank M, ..., Andersson CV, Sandberg K
J Biomol Screen 20 (9) 1112-1123 [2015-10-00; online 2015-06-12]
Affiliated researcher
Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets in vitro.
Kloster-Jensen K, Vethe NT, Bremer S, ..., Bergan S, Scholz H
Transpl. Int. 28 (10) 1152-1161 [2015-10-00; online 2015-06-23]
Affiliated researcher
In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome.
Simonson OE, Mougiakakos D, Heldring N, ..., Grinnemo KH, Le Blanc K
Stem Cells Transl Med 4 (10) 1199-1213 [2015-10-00; online 2015-08-18]
Affiliated researcher
Graft function 1 year after pregnancy in an islet-transplanted patient.
Schive SW, Scholz H, Sahraoui A, ..., Foss A, Jenssen TG
Transpl. Int. 28 (10) 1235-1239 [2015-10-00; online 2015-05-11]
Affiliated researcher
Flight-induced changes in gene expression in the Glanville fritillary butterfly.
Kvist J, Mattila AL, Somervuo P, ..., Frilander MJ, Hanski I
Mol. Ecol. 24 (19) 4886-4900 [2015-10-00; online 2015-09-04]
Affiliated researcher
Acoustophoretic removal of proteins from blood components.
Tenje M, Lundgren MN, Swärd-Nilsson AM, ..., Lyxe L, Lenshof A
Biomed Microdevices 17 (5) 95 [2015-10-00; online 2015-09-01]
Affiliated researcher
Acid-Base Catalyst Discriminates between a Fructose 6-Phosphate Aldolase and a Transaldolase
Stellmacher L, Sandalova T, Leptihn S, ..., Sprenger GA, Samland AK
ChemCatChem 7 (19) 3140-3151 [2015-10-00; online 2015-08-06]
Affiliated researcher
Serendipitous Meta-Transcriptomics: The Fungal Community of Norway Spruce (Picea abies).
Delhomme N, Sundström G, Zamani N, ..., Grabherr MG, Street NR
PLoS ONE 10 (9) e0139080 [2015-09-28; online 2015-09-28]
Affiliated researcher
Identification of Novel Epigenetic Markers of Prostate Cancer by NotI-Microarray Analysis.
Dmitriev AA, Rosenberg EE, Krasnov GS, ..., Senchenko VN, Kashuba VI
Dis. Markers 2015 (-) 241301 [2015-09-28; online 2015-09-28]
Affiliated researcher
Exploring microbial dark matter to resolve the deep archaeal ancestry of eukaryotes.
Saw JH, Spang A, Zaremba-Niedzwiedzka K, ..., Guy L, Ettema TJ
Philos. Trans. R. Soc. Lond., B, Biol. Sci. 370 (1678) 20140328 [2015-09-26; online 2015-09-02]
Affiliated researcher
Molecular architecture of the active mitochondrial protein gate.
Shiota T, Imai K, Qiu J, ..., Lithgow T, Endo T
Science 349 (6255) 1544-1548 [2015-09-25; online 2015-09-26]
Affiliated researcher
Highly specific DNA detection employing ligation on suspension bead array readout.
Mezger A, Kühnemund M, Nilsson M, Herthnek D
N Biotechnol 32 (5) 504-510 [2015-09-25; online 2015-02-11]
Affiliated researcher
Genome-wide maps of nuclear lamina interactions in single human cells.
Kind J, Pagie L, de Vries SS, ..., van Oudenaarden A, van Steensel B
Cell 163 (1) 134-147 [2015-09-24; online 2015-09-10]
Affiliated researcher Magda Bienko SciLifeLab Fellow
Ancient genomes link early farmers from Atapuerca in Spain to modern-day Basques.
Günther T, Valdiosera C, Malmström H, ..., Götherström A, Jakobsson M
Proc. Natl. Acad. Sci. U.S.A. 112 (38) 11917-11922 [2015-09-22; online 2015-09-08]
Affiliated researcher
Gene expression profiling of pre-eclamptic placentae by RNA sequencing.
Kaartokallio T, Cervera A, Kyllönen A, ..., Laivuori H, FINNPEC Core Investigator Group
Sci Rep 5 (-) 14107 [2015-09-21; online 2015-09-21]
Affiliated researcher
WNT3 involvement in human bladder exstrophy and cloaca development in zebrafish.
Baranowska Körberg I, Hofmeister W, Markljung E, ..., Lindstrand A, Nordenskjöld A
Hum. Mol. Genet. 24 (18) 5069-5078 [2015-09-15; online 2015-06-23]
Affiliated researcher
Modeling the mechanisms of biological GTP hydrolysis.
Carvalho AT, Szeler K, Vavitsas K, Åqvist J, Kamerlin SC
Arch. Biochem. Biophys. 582 (-) 80-90 [2015-09-15; online 2015-02-27]
Affiliated researcher
Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells.
Roy A, Coum A, Marinescu VD, ..., Pontén F, Tchougounova E
Oncotarget 6 (27) 23647-23661 [2015-09-15; online 2015-07-15]
Affiliated researcher
Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing.
Parry M, Rose-Zerilli MJ, Ljungström V, ..., Oscier D, Strefford JC
Clin. Cancer Res. 21 (18) 4174-4183 [2015-09-15; online 2015-03-16]
Affiliated researcher
Comparative genomic analyses of freshly isolated Giardia intestinalis assemblage A isolates.
Ankarklev J, Franzén O, Peirasmaki D, ..., Andersson B, Svärd SG
BMC Genomics 16 (-) 697 [2015-09-15; online 2015-09-15]
Affiliated researcher
E-cadherin can limit the transforming properties of activating β-catenin mutations.
Huels DJ, Ridgway RA, Radulescu S, ..., Clarke AR, Sansom OJ
EMBO J. 34 (18) 2321-2333 [2015-09-14; online 2015-08-03]
Affiliated researcher
Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF.
Huffman JE, de Vries PS, Morrison AC, ..., O'Donnell CJ, Smith NL
Blood 126 (11) e19-e29 [2015-09-10; online 2015-06-23]
Affiliated researcher
Cotranslational Protein Folding inside the Ribosome Exit Tunnel.
Nilsson OB, Hedman R, Marino J, ..., Beckmann R, von Heijne G
Cell Reports 12 (10) 1533-1540 [2015-09-08; online 2015-08-28]
Affiliated researcher
Roles of miR-196a on gene regulation of neuroendocrine tumor cells.
Li SC, Shi H, Khan M, ..., Öberg K, Giandomenico V
Mol. Cell. Endocrinol. 412 (-) 131-139 [2015-09-05; online 2015-06-04]
Affiliated researcher
Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project.
Horvatovich P, Lundberg EK, Chen YJ, ..., Paik YK, Hancock WS
J. Proteome Res. 14 (9) 3415-3431 [2015-09-04; online 2015-07-23]
Affiliated researcher
SUV3 helicase is required for correct processing of mitochondrial transcripts.
Clemente P, Pajak A, Laine I, ..., Freyer C, Wredenberg A
Nucleic Acids Res. 43 (15) 7398-7413 [2015-09-03; online 2015-07-07]
Affiliated researcher
Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures.
Stödberg T, McTague A, Ruiz AJ, ..., Wedell A, Kurian MA
Nat Commun 6 (-) 8038 [2015-09-03; online 2015-09-03]
Affiliated researcher
Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis.
Rydén M, Uzunel M, Hård JL, ..., Mattsson J, Arner P
Cell Metab. 22 (3) 408-417 [2015-09-01; online 2015-07-16]
Affiliated researcher
Use of a proximity extension assay proteomics chip to discover new biomarkers for human atherosclerosis.
Lind L, Ärnlöv J, Lindahl B, ..., Sundström J, Ingelsson E
Atherosclerosis 242 (1) 205-210 [2015-09-00; online 2015-07-14]
Affiliated researcher
Transcriptomics of colour patterning and coloration shifts in crows.
Poelstra JW, Vijay N, Hoeppner MP, Wolf JB
Mol. Ecol. 24 (18) 4617-4628 [2015-09-00; online 2015-09-10]
Affiliated researcher
Towards a stereoselective synthesis of α,α-disubstituted proline analogues
Das SK, Bhatt N, Mujahid M, ..., Naicker T, Govender T
Tetrahedron Letters 56 (37) 5172-5174 [2015-09-00; online 2015-09-00]
Affiliated researcher
Synthesis of enantiopure angiotensin II type 2 receptor [AT2R] antagonist EMA401
Wakchaure PB, Bremberg U, Wannberg J, Larhed M
Tetrahedron 71 (38) 6881-6887 [2015-09-00; online 2015-09-00]
Affiliated researcher
Species Tree Inference Using a Mixture Model.
Ullah I, Parviainen P, Lagergren J
Mol. Biol. Evol. 32 (9) 2469-2482 [2015-09-00; online 2015-05-11]
Affiliated researcher
Newtonian cell interactions shape natural killer cell education.
Goodridge JP, Önfelt B, Malmberg KJ
Immunol. Rev. 267 (1) 197-213 [2015-09-00; online 2015-08-19]
Affiliated researcher
LMNB1-related autosomal-dominant leukodystrophy: Clinical and radiological course.
Finnsson J, Sundblom J, Dahl N, Melberg A, Raininko R
Ann. Neurol. 78 (3) 412-425 [2015-09-00; online 2015-07-27]
Affiliated researcher
Gut microbiome and innate immune response patterns in IgE-associated eczema.
West CE, Rydén P, Lundin D, ..., Tulic MK, Prescott SL
Clin. Exp. Allergy 45 (9) 1419-1429 [2015-09-00; online 2015-05-07]
Affiliated researcher
Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests.
Frånberg M, Gertow K, Hamsten A, ..., Lagergren J, Sennblad B
PLoS Genet 11 (9) e1005502 [2015-09-00; online 2015-09-24]
Affiliated researcher
Chlorophyll f-driven photosynthesis in a cavernous cyanobacterium.
Behrendt L, Brejnrod A, Schliep M, ..., Larkum AW, Kühl M
ISME J 9 (9) 2108-2111 [2015-09-00; online 2015-02-10]
Lars Behrendt SciLifeLab Fellow
Prenatal and Postpartum Evening Salivary Cortisol Levels in Association with Peripartum Depressive Symptoms.
Iliadis SI, Comasco E, Sylvén S, ..., Sundström Poromaa I, Skalkidou A
PLoS ONE 10 (8) e0135471 [2015-08-31; online 2015-08-31]
Erika Comasco SciLifeLab Fellow
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Kharaziha P, Chioureas D, Rutishauser D, ..., Nilsson S, Panaretakis T
Oncotarget 6 (25) 21740-21754 [2015-08-28; online 2015-04-07]
Affiliated researcher
The Nucleus-Localized Epidermal Growth Factor Receptor Is SUMOylated.
Packham S, Lin Y, Zhao Z, ..., Rutishauser D, Larsson O
Biochemistry 54 (33) 5157-5166 [2015-08-25; online 2015-08-14]
Affiliated researcher
POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans.
Raghavan M, Steinrücken M, Harris K, ..., Nielsen R, Willerslev E
Science 349 (6250) aab3884 [2015-08-21; online 2015-07-21]
Affiliated researcher
Increased resistance to proteasome inhibitors in multiple myeloma mediated by cIAP2--implications for a combinatorial treatment.
Fristedt Duvefelt C, Lub S, Agarwal P, ..., Vanderkerken K, Jernberg Wiklund H
Oncotarget 6 (24) 20621-20635 [2015-08-21; online 2015-06-04]
Affiliated researcher
Experiences with workflows for automating data-intensive bioinformatics.
Spjuth O, Bongcam-Rudloff E, Hernández GC, ..., Siretskiy A, Vassilev D
Biol. Direct 10 (-) 43 [2015-08-19; online 2015-08-19]
Affiliated researcher
miR-184 Regulates Pancreatic β-Cell Function According to Glucose Metabolism.
Tattikota SG, Rathjen T, Hausser J, ..., Friedländer MR, Poy MN
J Biol Chem 290 (33) 20284-20294 [2015-08-14; online 2015-07-07]
Affiliated researcher Marc Friedländer SciLifeLab Fellow
Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.
Persson J, Strawbridge RJ, McLeod O, ..., Hamsten A, IMPROVE Study Group
J Am Heart Assoc 4 (8) e001853 [2015-08-14; online 2015-08-14]
Affiliated researcher
Genome-wide association study of warfarin maintenance dose in a Brazilian sample.
Parra EJ, Botton MR, Perini JA, ..., Hutz MH, Suarez-Kurtz G
Pharmacogenomics 16 (11) 1253-1263 [2015-08-12; online 2015-08-12]
Affiliated researcher
A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12.
Bianchi M, Dahlgren S, Massey J, ..., Lingaas F, Rosengren Pielberg G
PLoS ONE 10 (8) e0134720 [2015-08-11; online 2015-08-11]
Affiliated researcher
Improved canine exome designs, featuring ncRNAs and increased coverage of protein coding genes.
Broeckx BJ, Hitte C, Coopman F, ..., Van Nieuwerburgh F, Deforce D
Sci Rep 5 (-) 12810 [2015-08-03; online 2015-08-03]
Affiliated researcher
Identifying and Assessing Interesting Subgroups in a Heterogeneous Population.
Lee W, Alexeyenko A, Pernemalm M, ..., Lehtiö J, Pawitan Y
Biomed Res Int 2015 (-) 462549 [2015-08-03; online 2015-08-03]
Affiliated researcher
Heat differentiated complement factor profiling.
Hamsten C, Skattum L, Truedsson L, ..., Nilsson P, Neiman M
J Proteomics 126 (-) 155-162 [2015-08-03; online 2015-06-03]
Affiliated researcher
Genome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution.
Sahlén P, Abdullayev I, Ramsköld D, ..., Lundeberg J, Sandberg R
Genome Biol. 16 (-) 156 [2015-08-03; online 2015-08-03]
Affiliated researcher
Secretome protein signature of human gastrointestinal stromal tumor cells.
Berglund E, Daré E, Branca RM, ..., Kim J, Bränström R
Exp. Cell Res. 336 (1) 158-170 [2015-08-01; online 2015-05-14]
Affiliated researcher
Effect of genetic variations on ticagrelor plasma levels and clinical outcomes.
Varenhorst C, Eriksson N, Johansson Å, ..., Wallentin L, PLATO Investigators
Eur. Heart J. 36 (29) 1901-1912 [2015-08-01; online 2015-05-02]
Affiliated researcher
Vaccines targeting self-antigens: mechanisms and efficacy-determining parameters.
Saupe F, Huijbers EJ, Hein T, ..., Olsson AK, Hellman L
FASEB J. 29 (8) 3253-3262 [2015-08-00; online 2015-04-13]
Affiliated researcher
Inflammasomes of the intestinal epithelium
Sellin ME, Maslowski KM, Maloy KJ, Hardt WD
Trends in Immunology 36 (8) 442-450 [2015-08-00; online 2015-08-00]
Mikael Sellin SciLifeLab Fellow
Global miRNA expression and correlation with mRNA levels in primary human bone cells.
Laxman N, Rubin CJ, Mallmin H, ..., Grundberg E, Kindmark A
RNA 21 (8) 1433-1443 [2015-08-00; online 2015-06-15]
Affiliated researcher
Clade- and species-specific features of genome evolution in the Saccharomycetaceae.
Wolfe KH, Armisén D, Proux-Wera E, ..., Gordon JL, Byrne KP
FEMS Yeast Res. 15 (5) fov035 [2015-08-00; online 2015-06-10]
Affiliated researcher
OCDB: a database collecting genes, miRNAs and drugs for obsessive-compulsive disorder.
Privitera AP, Distefano R, Wefer HA, ..., Pulvirenti A, Giugno R
Database (Oxford) 2015 (-) bav069 [2015-07-30; online 2015-07-30]
Affiliated researcher
Genome-Wide Analyses Suggest Mechanisms Involving Early B-Cell Development in Canine IgA Deficiency.
Olsson M, Tengvall K, Frankowiack M, ..., Hammarström L, Lindblad-Toh K
PLoS ONE 10 (7) e0133844 [2015-07-30; online 2015-07-30]
Affiliated researcher
Directional dominance on stature and cognition in diverse human populations.
Joshi PK, Esko T, Mattsson H, ..., Polašek O, Wilson JF
Nature 523 (7561) 459-462 [2015-07-23; online 2015-07-01]
Affiliated researcher
DNA rendering of polyhedral meshes at the nanoscale.
Benson E, Mohammed A, Gardell J, ..., Orponen P, Högberg B
Nature 523 (7561) 441-444 [2015-07-23; online 2015-07-24]
Erik Benson SciLifeLab Fellow
Compaction of rolling circle amplification products increases signal integrity and signal-to-noise ratio.
Clausson CM, Arngården L, Ishaq O, ..., Wählby C, Söderberg O
Sci Rep 5 (-) 12317 [2015-07-23; online 2015-07-23]
Affiliated researcher
lobChIP: from cells to sequencing ready ChIP libraries in a single day.
Wallerman O, Nord H, Bysani M, Borghini L, Wadelius C
Epigenetics Chromatin 8 (-) 25 [2015-07-21; online 2015-07-21]
Affiliated researcher
CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface.
Yakymovych I, Yakymovych M, Zang G, ..., Landström M, Heldin CH
J. Cell Biol. 210 (2) 319-332 [2015-07-20; online 2015-07-13]
Affiliated researcher
Mitochondrial ribosome assembly in health and disease
De Silva D, Tu YT, Amunts A, Fontanesi F, Barrientos A
Cell Cycle 14 (14) 2226-2250 [2015-07-18; online 2015-06-00]
Alexey Amunts SciLifeLab Fellow
Epigenome data release: a participant-centered approach to privacy protection.
Dyke SO, Cheung WA, Joly Y, ..., Walter J, Pastinen T
Genome Biol. 16 (-) 142 [2015-07-17; online 2015-07-17]
Affiliated researcher
SAXS-Guided Metadynamics.
Kimanius D, Pettersson I, Schluckebier G, Lindahl E, Andersson M
J Chem Theory Comput 11 (7) 3491-3498 [2015-07-14; online 2015-11-18]
Affiliated researcher
Properties of Organic Liquids when Simulated with Long-Range Lennard-Jones Interactions.
Fischer NM, van Maaren PJ, Ditz JC, Yildirim A, van der Spoel D
J Chem Theory Comput 11 (7) 2938-2944 [2015-07-14; online 2015-06-02]
Affiliated researcher
Incidence of Diabetes Mellitus in Insured Swedish Cats in Relation to Age, Breed and Sex.
Öhlund M, Fall T, Ström Holst B, ..., Bonnett B, Egenvall A
J. Vet. Intern. Med. 29 (5) 1342-1347 [2015-07-14; online 2015-07-14]
Affiliated researcher
Chromosomal copy number variation reveals differential levels of genomic plasticity in distinct Trypanosoma cruzi strains.
Reis-Cunha JL, Rodrigues-Luiz GF, Valdivia HO, ..., Vasconcelos AT, Bartholomeu DC
BMC Genomics 16 (-) 499 [2015-07-04; online 2015-07-04]
Affiliated researcher
A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer.
Dietlein F, Kalb B, Jokic M, ..., Thomas RK, Reinhardt HC
Cell 162 (1) 146-159 [2015-07-02; online 2015-07-04]
Affiliated researcher
Critical Role of Histone Turnover in Neuronal Transcription and Plasticity.
Maze I, Wenderski W, Noh KM, ..., Molina H, Allis CD
Neuron 87 (1) 77-94 [2015-07-01; online 2015-07-04]
SciLifeLab Fellow Simon Elsässer
Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes.
Fall T, Xie W, Poon W, ..., Frayling TM, Ingelsson E
Diabetes 64 (7) 2676-2684 [2015-07-00; online 2015-05-06]
Affiliated researcher
The Nuclear PolyA-Binding Protein Nab2p Is Essential for mRNA Production
Schmid M, Olszewski P, Pelechano V, ..., Steinmetz LM, Jensen TH
Cell Reports 12 (1) 128-139 [2015-07-00; online 2015-07-00]
SciLifeLab Fellow Vicent Pelechano
Quality of life in patients with venous thromboembolism and atrial fibrillation treated with coumarin anticoagulants.
Marvig CL, Verhoef TI, de Boer A, ..., Maitland-van der Zee AH, EU-PACT consortium
Thromb. Res. 136 (1) 69-75 [2015-07-00; online 2015-04-25]
Affiliated researcher
Polymorphisms in DCDC2 and S100B associate with developmental dyslexia.
Matsson H, Huss M, Persson H, ..., Peyrard-Janvid M, Kere J
J. Hum. Genet. 60 (7) 399-401 [2015-07-00; online 2015-04-16]
Affiliated researcher
Neuroproteomics tools in clinical practice.
Shevchenko G, Konzer A, Musunuri S, Bergquist J
Biochim. Biophys. Acta 1854 (7) 705-717 [2015-07-00; online 2015-02-10]
Affiliated researcher
High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.
Varshney GK, Pei W, LaFave MC, ..., Ledin J, Burgess SM
Genome Res. 25 (7) 1030-1042 [2015-07-00; online 2015-06-05]
Affiliated researcher
Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro.
Heiss M, Hellström M, Kalén M, ..., Augustin HG, Korff T
FASEB J. 29 (7) 3076-3084 [2015-07-00; online 2015-04-09]
Affiliated researcher
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.
Horikoshi M, Mӓgi R, van de Bunt M, ..., Morris AP, ENGAGE Consortium
PLoS Genet 11 (7) e1005230 [2015-07-00; online 2015-07-01]
Affiliated researcher
Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate.
Trésaugues L, Lundbäck T, Welin M, ..., Gräslund S, Nordlund P
PLoS ONE 10 (6) e0131507 [2015-06-29; online 2015-06-29]
Affiliated researcher
Transcriptional modulator ZBED6 affects cell cycle and growth of human colorectal cancer cells.
Akhtar Ali M, Younis S, Wallerman O, ..., Andersson L, Sjöblom T
Proc. Natl. Acad. Sci. U.S.A. 112 (25) 7743-7748 [2015-06-23; online 2015-06-08]
Affiliated researcher
Linked genetic variants on chromosome 10 control ear morphology and body mass among dog breeds.
Webster MT, Kamgari N, Perloski M, ..., Pielberg G, Lindblad-Toh K
BMC Genomics 16 (-) 474 [2015-06-23; online 2015-06-23]
Affiliated researcher
Transglutaminase 4 as a prostate autoantigen in male subfertility.
Landegren N, Sharon D, Shum AK, ..., Snyder M, Kämpe O
Sci Transl Med 7 (292) 292ra101 [2015-06-17; online 2015-06-19]
Affiliated researcher
Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome.
Gu Urban GJ, Friedman M, Ren P, ..., Landegren U, Kamali-Moghaddam M
Sci Rep 5 (-) 11196 [2015-06-16; online 2015-06-16]
Affiliated researcher
Mobility-based prediction of hydration structures of protein surfaces.
Jeszenői N, Horváth I, Bálint M, van der Spoel D, Hetényi C
Bioinformatics 31 (12) 1959-1965 [2015-06-15; online 2015-02-13]
Affiliated researcher
Proximity-dependent initiation of hybridization chain reaction.
Koos B, Cane G, Grannas K, ..., Kamali-Moghaddam M, Söderberg O
Nat Commun 6 (-) 7294 [2015-06-12; online 2015-06-12]
Affiliated researcher
Phasing of single DNA molecules by massively parallel barcoding.
Borgström E, Redin D, Lundin S, ..., Andersson AF, Ahmadian A
Nat Commun 6 (-) 7173 [2015-06-09; online 2015-06-09]
Affiliated researcher
Next-generation pathology--surveillance of tumor microecology.
Koos B, Kamali-Moghaddam M, David L, ..., Wählby C, Söderberg O
J. Mol. Biol. 427 (11) 2013-2022 [2015-06-05; online 2015-02-26]
Affiliated researcher
Single-cell polyadenylation site mapping reveals 3' isoform choice variability.
Velten L, Anders S, Pekowska A, ..., Pelechano V, Steinmetz LM
Mol Syst Biol 11 (6) 812 [2015-06-03; online 2015-06-03]
SciLifeLab Fellow Vicent Pelechano
Processing of protein ADP-ribosylation by Nudix hydrolases.
Palazzo L, Thomas B, Jemth AS, ..., Helleday T, Ahel I
Biochem. J. 468 (2) 293-301 [2015-06-01; online 2015-03-20]
Affiliated researcher
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia.
Mansouri L, Sutton LA, Ljungström V, ..., Nilsson M, Rosenquist R
J. Exp. Med. 212 (6) 833-843 [2015-06-01; online 2015-05-18]
Affiliated researcher
The impact of low-frequency and rare variants on lipid levels.
Surakka I, Horikoshi M, Mägi R, ..., Ripatti S, ENGAGE Consortium
Nat. Genet. 47 (6) 589-597 [2015-06-00; online 2015-05-11]
Affiliated researcher
Significance of archaeal nitrification in hypoxic waters of the Baltic Sea.
Berg C, Vandieken V, Thamdrup B, Jürgens K
ISME J 9 (6) 1319-1332 [2015-06-00; online 2014-11-25]
Affiliated researcher
Multiple Changes of Gene Expression and Function Reveal Genomic and Phenotypic Complexity in SLE-like Disease.
Wilbe M, Kozyrev SV, Farias FH, ..., Hansson-Hamlin H, Lindblad-Toh K
PLoS Genet 11 (6) e1005248 [2015-06-00; online 2015-06-09]
Affiliated researcher
Molecular evidence for antigen drive in the natural history of mantle cell lymphoma.
Xochelli A, Sutton LA, Agathangelidis A, ..., Belessi C, Stamatopoulos K
Am. J. Pathol. 185 (6) 1740-1748 [2015-06-00; online 2015-04-02]
Affiliated researcher
MATHEMATICAL MODELING OF BEHÇET'S DISEASE: A DYNAMICAL SYSTEMS APPROACH
ERDEM C, BOZKURT Y, ERMAN B, GÜL A, DEMIR A
J. Biol. Syst. 23 (02) 231-257 [2015-06-00; online 2015-05-28]
Cemal Erdem DDLS Fellow
Human adaptation to arsenic-rich environments.
Schlebusch CM, Gattepaille LM, Engström K, ..., Jakobsson M, Broberg K
Mol. Biol. Evol. 32 (6) 1544-1555 [2015-06-00; online 2015-03-03]
Affiliated researcher
Exome sequencing of contralateral breast cancer identifies metastatic disease.
Klevebring D, Lindberg J, Rockberg J, ..., Sandberg M, Czene K
Breast Cancer Res. Treat. 151 (2) 319-324 [2015-06-00; online 2015-04-29]
Affiliated researcher
Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.
Swaminathan B, Thorleifsson G, Jöud M, ..., Thorsteinsdóttir U, Nilsson B
Nat Commun 6 (1) 7213 [2015-05-26; online 2015-05-26]
Affiliated researcher
Estrogen Receptor β2 Induces Hypoxia Signature of Gene Expression by Stabilizing HIF-1α in Prostate Cancer.
Dey P, Velazquez-Villegas LA, Faria M, ..., Gustafsson JÅ, Ström AM
PLoS ONE 10 (5) e0128239 [2015-05-26; online 2015-05-26]
Affiliated researcher
Spectral imaging to measure heterogeneity in membrane lipid packing.
Sezgin E, Waithe D, Bernardino de la Serna J, Eggeling C
Chemphyschem 16 (7) 1387-1394 [2015-05-18; online 2015-03-05]
Erdinc Sezgin SciLifeLab Fellow
CGGBP1 mitigates cytosine methylation at repetitive DNA sequences.
Agarwal P, Collier P, Fritz MH, ..., Westermark B, Singh U
BMC Genomics 16 (-) 390 [2015-05-16; online 2015-05-16]
Affiliated researcher
Obesity, metabolic syndrome and risk of atrial fibrillation: a Swedish, prospective cohort study.
Nyström PK, Carlsson AC, Leander K, ..., Hellenius ML, Gigante B
PLoS ONE 10 (5) e0127111 [2015-05-15; online 2015-05-15]
Affiliated researcher
Complex archaea that bridge the gap between prokaryotes and eukaryotes.
Spang A, Saw JH, Jørgensen SL, ..., Guy L, Ettema TJG
Nature 521 (7551) 173-179 [2015-05-14; online 2015-05-06]
Affiliated researcher
Vinylic MIDA Boronates: New Building Blocks for the Synthesis of Aza-Heterocycles.
Llona-Minguez S, Desroses M, Ghassemian A, ..., Scobie M, Helleday T
Chemistry 21 (20) 7394-7398 [2015-05-11; online 2015-03-25]
Affiliated researcher
Somatostatin Analogs Treated Small Intestinal Neuroendocrine Tumor Patients Circulating MicroRNAs.
Li SC, Khan M, Caplin M, ..., Öberg K, Giandomenico V
PLoS ONE 10 (5) e0125553 [2015-05-05; online 2015-05-05]
Affiliated researcher
Intestinal dysbiosis in children with short bowel syndrome is associated with impaired outcome.
Engstrand Lilja H, Wefer H, Nyström N, Finkel Y, Engstrand L
Microbiome 3 (-) 18 [2015-05-04; online 2015-05-04]
Affiliated researcher
Coordinated expression of DNAM-1 and LFA-1 in educated NK cells.
Enqvist M, Ask EH, Forslund E, ..., Önfelt B, Malmberg KJ
J. Immunol. 194 (9) 4518-4527 [2015-05-01; online 2015-03-30]
Affiliated researcher
Tracking the origin of metastatic prostate cancer.
Lindberg J, Kristiansen A, Wiklund P, Grönberg H, Egevad L
Eur. Urol. 67 (5) 819-822 [2015-05-00; online 2014-09-22]
Affiliated researcher
Recent advances in QM/MM free energy calculations using reference potentials.
Duarte F, Amrein BA, Blaha-Nelson D, Kamerlin SCL
Biochim. Biophys. Acta 1850 (5) 954-965 [2015-05-00; online 2014-07-16]
Affiliated researcher
Quantifying the impact of transporters on cellular drug permeability.
Matsson P, Fenu LA, Lundquist P, ..., Kansy M, Artursson P
Trends Pharmacol. Sci. 36 (5) 255-262 [2015-05-00; online 2015-03-19]
Affiliated researcher
Predictors of recurrent cellulitis in five years. Clinical risk factors and the role of PTX3 and CRP.
Karppelin M, Siljander T, Aittoniemi J, ..., Vuopio J, Syrjänen J
J. Infect. 70 (5) 467-473 [2015-05-00; online 2014-11-15]
Affiliated researcher
ITS1: a DNA barcode better than ITS2 in eukaryotes?
Wang XC, Liu C, Huang L, ..., Cai D, Li JQ
Mol Ecol Resour 15 (3) 573-586 [2015-05-00; online 2014-09-24]
DDLS Fellow Johan Bengtsson-Palme
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.
Coffee and Caffeine Genetics Consortium , Cornelis MC, Byrne EM, ..., van Dam RM, Chasman DI
Mol. Psychiatry 20 (5) 647-656 [2015-05-00; online 2014-10-07]
Affiliated researcher
Diagnostic urinary proteome profile for immunoglobulin a nephropathy.
Samavat S, Kalantari S, Nafar M, ..., Parvin M, Zubarev RA
Iran J Kidney Dis 9 (3) 239-248 [2015-05-00; online 2015-05-10]
Affiliated researcher
Autoantibody response against NALP5/MATER in primary ovarian insufficiency and in autoimmune Addison's disease.
Brozzetti A, Alimohammadi M, Morelli S, ..., Falorni A, Italian Addison Network
J. Clin. Endocrinol. Metab. 100 (5) 1941-1948 [2015-05-00; online 2015-03-03]
Affiliated researcher
Age- and sex-specific causal effects of adiposity on cardiovascular risk factors.
Fall T, Hägg S, Ploner A, ..., Ingelsson E, ENGAGE Consortium
Diabetes 64 (5) 1841-1852 [2015-05-00; online 2015-02-23]
Affiliated researcher
African origin for Madagascan dogs revealed by mtDNA analysis.
Ardalan A, Oskarsson MC, van Asch B, Rabakonandriania E, Savolainen P
R Soc Open Sci 2 (5) 140552 [2015-05-00; online 2015-05-20]
Affiliated researcher
Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery.
Mørch Ý, Hansen R, Berg S, ..., de Lange Davies C, Stenstad PM
Contrast Media Mol Imaging 10 (5) 356-366 [2015-04-30; online 2015-04-30]
Affiliated researcher
An epigenome-wide association study of total serum immunoglobulin E concentration.
Liang L, Willis-Owen SAG, Laprise C, ..., Moffatt MF, Cookson WOCM
Nature 520 (7549) 670-674 [2015-04-30; online 2015-02-18]
Affiliated researcher
Membrane nanoclusters-tails of the unexpected.
Sezgin E, Davis SJ, Eggeling C
Cell 161 (3) 433-434 [2015-04-23; online 2015-04-25]
Erdinc Sezgin SciLifeLab Fellow
Genetically determined height and coronary artery disease.
Nelson CP, Hamby SE, Saleheen D, ..., Samani NJ, CARDIoGRAM+C4D Consortium
N. Engl. J. Med. 372 (17) 1608-1618 [2015-04-23; online 2015-04-08]
Affiliated researcher
Adaptive lipid packing and bioactivity in membrane domains.
Sezgin E, Gutmann T, Buhl T, ..., Levental I, Schwille P
PLoS ONE 10 (4) e0123930 [2015-04-23; online 2015-04-23]
Erdinc Sezgin SciLifeLab Fellow
Exploration of the arrest peptide sequence space reveals arrest-enhanced variants.
Cymer F, Hedman R, Ismail N, von Heijne G
J. Biol. Chem. 290 (16) 10208-10215 [2015-04-17; online 2015-02-24]
Affiliated researcher
Extensive intra-phylotype diversity in lactobacilli and bifidobacteria from the honeybee gut.
Ellegaard KM, Tamarit D, Javelind E, ..., Andersson SG, Vásquez A
BMC Genomics 16 (-) 284 [2015-04-11; online 2015-04-11]
Affiliated researcher
Synthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Chofor R, Sooriyaarachchi S, Risseeuw MD, ..., Mowbray SL, Van Calenbergh S
J. Med. Chem. 58 (7) 2988-3001 [2015-04-09; online 2015-03-31]
Affiliated researcher
The structure of the human mitochondrial ribosome
Amunts A, Brown A, Toots J, Scheres SHW, Ramakrishnan V
Science 348 (6230) 95-98 [2015-04-03; online 2015-04-02]
Alexey Amunts SciLifeLab Fellow
Behavioral cost & overdominance in Anopheles gambiae.
Diop MM, Moiroux N, Chandre F, ..., Labbé P, Pennetier C
PLoS ONE 10 (4) e0121755 [2015-04-01; online 2015-04-01]
Pascal Milesi SciLifeLab Fellow
RIFINs are adhesins implicated in severe Plasmodium falciparum malaria.
Goel S, Palmkvist M, Moll K, ..., Nilsson I, Wahlgren M
Nat. Med. 21 (4) 314-317 [2015-04-00; online 2015-03-09]
Affiliated researcher
Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains.
Beck-García K, Beck-García E, Bohler S, ..., Alarcón B, Schamel WW
Biochim. Biophys. Acta 1853 (4) 802-809 [2015-04-00; online 2014-12-20]
Erdinc Sezgin SciLifeLab Fellow
Molecular histology of lung cancer: from targets to treatments.
Wood SL, Pernemalm M, Crosbie PA, Whetton AD
Cancer Treat. Rev. 41 (4) 361-375 [2015-04-00; online 2015-02-20]
Affiliated researcher
Microfluidic-based isolation of bacteria from whole blood for sepsis diagnostics.
Zelenin S, Hansson J, Ardabili S, ..., Brismar H, Russom A
Biotechnol. Lett. 37 (4) 825-830 [2015-04-00; online 2014-11-21]
Affiliated researcher
Duffy antigen receptor genetic variant and the association with Interleukin 8 levels.
Moreno Velásquez I, Kumar J, Björkbacka H, ..., de Faire U, Gigante B
Cytokine 72 (2) 178-184 [2015-04-00; online 2015-01-31]
Affiliated researcher
Calcium signaling in neocortical development.
Uhlén P, Fritz N, Smedler E, Malmersjö S, Kanatani S
Dev Neurobiol 75 (4) 360-368 [2015-04-00; online 2015-02-18]
Affiliated researcher
Adiposity as a cause of cardiovascular disease: a Mendelian randomization study.
Hägg S, Fall T, Ploner A, ..., Ingelsson E, European Network for Genetic and Genomic Epidemiology Consortium
Int J Epidemiol 44 (2) 578-586 [2015-04-00; online 2015-05-27]
Affiliated researcher
Aberrant post-translational modifications compromise human myosin motor function in old age.
Li M, Ogilvie H, Ochala J, ..., Bergquist J, Larsson L
Aging Cell 14 (2) 228-235 [2015-04-00; online 2015-02-02]
Affiliated researcher
Dissecting antibodies with regards to linear and conformational epitopes.
Forsström B, Axnäs BB, Rockberg J, ..., Bohlin A, Uhlen M
PLoS ONE 10 (3) e0121673 [2015-03-27; online 2015-03-27]
Affiliated researcher
Catalytic stimulation by restrained active-site floppiness--the case of high density lipoprotein-bound serum paraoxonase-1.
Ben-David M, Sussman JL, Maxwell CI, ..., Kamerlin SCL, Tawfik DS
J. Mol. Biol. 427 (6 Pt B) 1359-1374 [2015-03-27; online 2015-01-30]
Affiliated researcher
Crystal structures of the kinase domain of the sulfate-activating complex in Mycobacterium tuberculosis.
Poyraz Ö, Brunner K, Lohkamp B, ..., Schnell R, Schneider G
PLoS ONE 10 (3) e0121494 [2015-03-25; online 2015-03-25]
Affiliated researcher
Chondroitin / dermatan sulfate modification enzymes in zebrafish development.
Habicher J, Haitina T, Eriksson I, ..., Ahlberg PE, Ledin J
PLoS ONE 10 (3) e0121957 [2015-03-20; online 2015-03-20]
Affiliated researcher
The NDST gene family in zebrafish: role of NDST1B in pharyngeal arch formation.
Filipek-Górniok B, Carlsson P, Haitina T, ..., Ledin J, Kjellén L
PLoS ONE 10 (3) e0119040 [2015-03-13; online 2015-03-13]
Affiliated researcher
Mechanisms of integral membrane protein insertion and folding.
Cymer F, von Heijne G, White SH
J. Mol. Biol. 427 (5) 999-1022 [2015-03-13; online 2014-09-30]
Affiliated researcher
How valence bond theory can help you understand your (bio)chemical reaction.
Shurki A, Derat E, Barrozo A, Kamerlin SC
Chem Soc Rev 44 (5) 1037-1052 [2015-03-07; online 2014-10-30]
Affiliated researcher
Proteomic profiling reveals autoimmune targets in sarcoidosis.
Häggmark A, Hamsten C, Wiklundh E, ..., Grunewald J, Nilsson P
Am. J. Respir. Crit. Care Med. 191 (5) 574-583 [2015-03-01; online 2015-01-22]
Affiliated researcher
Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function.
Uematsu K, Heiman M, Zelenina M, ..., Nishi A, Greengard P
J. Neurochem. 132 (6) 677-686 [2015-03-00; online 2015-03-04]
Affiliated researcher
Plasma IL-5 concentration and subclinical carotid atherosclerosis.
Silveira A, McLeod O, Strawbridge RJ, ..., de Faire U, Hamsten A
Atherosclerosis 239 (1) 125-130 [2015-03-00; online 2014-12-23]
Affiliated researcher
Pharmacotherapy and mortality in atrial fibrillation--a cohort of men and women 75 years or older in Sweden.
Wändell PE, Carlsson AC, Sundquist J, ..., Bottai M, Sundquist K
Age Ageing 44 (2) 232-238 [2015-03-00; online 2014-10-16]
Affiliated researcher
PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6.
Oparina NY, Delgado-Vega AM, Martinez-Bueno M, ..., Alarcon-Riquelme ME, Kozyrev SV
Ann. Rheum. Dis. 74 (3) e14 [2015-03-00; online 2014-02-17]
Affiliated researcher
MuSK: a new target for lethal fetal akinesia deformation sequence (FADS).
Wilbe M, Ekvall S, Eurenius K, ..., Annerén G, Bondeson ML
J. Med. Genet. 52 (3) 195-202 [2015-03-00; online 2015-01-22]
Affiliated researcher
Imaging of a clinically relevant stroke model: glucose hypermetabolism revisited.
Arnberg F, Grafström J, Lundberg J, ..., Stone-Elander S, Holmin S
Stroke 46 (3) 835-842 [2015-03-00; online 2015-02-05]
Affiliated researcher
FGF2 as a potential prognostic biomarker for proneural glioma patients.
Sooman L, Freyhult E, Jaiswal A, ..., Bergqvist M, Ekman S
Acta Oncol 54 (3) 385-394 [2015-03-00; online 2014-09-29]
Affiliated researcher
Convergent evolution of the genomes of marine mammals.
Foote AD, Liu Y, Thomas GW, ..., Gilbert MT, Gibbs RA
Nat. Genet. 47 (3) 272-275 [2015-03-00; online 2015-01-26]
Affiliated researcher
A genomic duplication is associated with ectopic eomesodermin expression in the embryonic chicken comb and two duplex-comb phenotypes.
Dorshorst B, Harun-Or-Rashid M, Bagherpoor AJ, ..., Hallböök F, Andersson L
PLoS Genet 11 (3) e1004947 [2015-03-00; online 2015-03-19]
Affiliated researcher
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.
Arner E, Daub CO, Vitting-Seerup K, ..., Carninci P, Hayashizaki Y
Science 347 (6225) 1010-1014 [2015-02-27; online 2015-02-12]
Affiliated researcher
Influence of antifreeze proteins on the ice/water interface.
Todde G, Hovmöller S, Laaksonen A
J Phys Chem B 119 (8) 3407-3413 [2015-02-26; online 2015-02-10]
Affiliated researcher
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci.
Jäger R, Migliorini G, Henrion M, ..., Fletcher O, Houlston RS
Nat Commun 6 (-) 6178 [2015-02-19; online 2015-02-19]
Affiliated researcher
DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia.
Nordlund J, Bäcklin CL, Zachariadis V, ..., Forestier E, Syvänen AC
Clin Epigenetics 7 (-) 11 [2015-02-17; online 2015-02-17]
Affiliated researcher
New genetic loci link adipose and insulin biology to body fat distribution.
Shungin D, Winkler TW, Croteau-Chonka DC, ..., Lindgren CM, Mohlke KL
Nature 518 (7538) 187-196 [2015-02-12; online 2015-02-13]
Affiliated researcher
Genetic studies of body mass index yield new insights for obesity biology.
Locke AE, Kahali B, Berndt SI, ..., Loos RJF, Speliotes EK
Nature 518 (7538) 197-206 [2015-02-12; online 2015-02-13]
Affiliated researcher
Clonal distribution of BCR-ABL1 mutations and splice isoforms by single-molecule long-read RNA sequencing.
Cavelier L, Ameur A, Häggqvist S, ..., Olsson-Strömberg U, Hermanson M
BMC Cancer 15 (-) 45 [2015-02-12; online 2015-02-12]
Affiliated researcher
Deciphering solution scattering data with experimentally guided molecular dynamics simulations.
Björling A, Niebling S, Marcellini M, van der Spoel D, Westenhoff S
J Chem Theory Comput 11 (2) 780-787 [2015-02-10; online 2015-02-18]
Affiliated researcher
Flagellin as carrier and adjuvant in cocaine vaccine development.
Lockner JW, Eubanks LM, Choi JL, ..., Wilson IA, Janda KD
Mol. Pharm. 12 (2) 653-662 [2015-02-02; online 2015-01-07]
Daniel Globisch SciLifeLab Fellow
Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation.
Panas MD, Schulte T, Thaa B, ..., Achour A, McInerney GM
PLoS Pathog 11 (2) e1004659 [2015-02-00; online 2015-02-06]
Affiliated researcher
Splenic marginal-zone lymphoma: ontogeny and genetics.
Baliakas P, Strefford JC, Bikos V, ..., Stamatopoulos K, Oscier D
Leuk. Lymphoma 56 (2) 301-310 [2015-02-00; online 2014-08-19]
Affiliated researcher
Recurrent mutations refine prognosis in chronic lymphocytic leukemia.
Baliakas P, Hadzidimitriou A, Sutton LA, ..., Rosenquist R, European Research Initiative on CLL (ERIC)
Leukemia 29 (2) 329-336 [2015-02-00; online 2014-06-19]
Affiliated researcher
Predicting venous thrombosis in women using a combination of genetic markers and clinical risk factors.
Bruzelius M, Bottai M, Sabater-Lleal M, ..., Hamsten A, Odeberg J
J. Thromb. Haemost. 13 (2) 219-227 [2015-02-00; online 2015-01-12]
Affiliated researcher
Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers.
Tonomura N, Elvers I, Thomas R, ..., Breen M, Lindblad-Toh K
PLoS Genet 11 (2) e1004922 [2015-02-00; online 2015-02-02]
Affiliated researcher
Expression of human skin-specific genes defined by transcriptomics and antibody-based profiling.
Edqvist PH, Fagerberg L, Hallström BM, ..., Uhlén M, Pontén F
J. Histochem. Cytochem. 63 (2) 129-141 [2015-02-00; online 2014-11-19]
Affiliated researcher
CTNND2-a candidate gene for reading problems and mild intellectual disability.
Hofmeister W, Nilsson D, Topa A, ..., Syk Lundberg E, Lindstrand A
J. Med. Genet. 52 (2) 111-122 [2015-02-00; online 2014-12-03]
Affiliated researcher
Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics
Amunts A, Fiedorczuk K, Truong TT, ..., Greenberg EP, Ramakrishnan V
Journal of Molecular Biology 427 (4) 753-755 [2015-02-00; online 2015-02-00]
Alexey Amunts SciLifeLab Fellow
Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle
Jordán-Pla A, Gupta I, de Miguel-Jiménez L, ..., Pelechano V, Pérez-Ortín JE
Nucleic Acids Res. 43 (2) 787-802 [2015-01-30; online 2014-12-29]
SciLifeLab Fellow Vicent Pelechano
Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations.
Baliakas P, Agathangelidis A, Hadzidimitriou A, ..., Rosenquist R, Stamatopoulos K
Blood 125 (5) 856-859 [2015-01-29; online 2014-12-17]
Affiliated researcher
Endonuclease specificity and sequence dependence of type IIS restriction enzymes.
Lundin S, Jemt A, Terje-Hegge F, ..., Lexow P, Lundeberg J
PLoS ONE 10 (1) e0117059 [2015-01-28; online 2015-01-28]
Affiliated researcher
Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.
Mengelbier LH, Karlsson J, Lindgren D, ..., Mayrhofer M, Gisselsson D
Nat Commun 6 (-) 6125 [2015-01-27; online 2015-01-27]
Affiliated researcher
Scaling predictive modeling in drug development with cloud computing.
Moghadam BT, Alvarsson J, Holm M, ..., Carlsson L, Spjuth O
J Chem Inf Model 55 (1) 19-25 [2015-01-26; online 2015-01-08]
Affiliated researcher
Proteomics. Tissue-based map of the human proteome.
Uhlén M, Fagerberg L, Hallström BM, ..., Nielsen J, Pontén F
Science (New York, N.Y.) 347 (6220) 1260419 [2015-01-23; online 2015-01-24]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.
Westcott PM, Halliwill KD, To MD, ..., Adams DJ, Balmain A
Nature 517 (7535) 489-492 [2015-01-22; online 2014-11-02]
Affiliated researcher
Biological interpretation of genome-wide association studies using predicted gene functions.
Pers TH, Karjalainen JM, Chan Y, ..., Hirschhorn JN, Franke L
Nat Commun 6 (-) 5890 [2015-01-19; online 2015-01-19]
Affiliated researcher
Variation in the human immune system is largely driven by non-heritable influences.
Brodin P, Jojic V, Gao T, ..., Maecker HT, Davis MM
Cell 160 (1-2) 37-47 [2015-01-15; online 2015-01-17]
Affiliated researcher
A proteomic approach to monitor the dynamic response of the female oviductal epithelial cell surface to male gametes.
Artemenko K, Horáková J, Steinberger B, ..., Bergquist J, Mayrhofer C
J Proteomics 113 (-) 1-14 [2015-01-15; online 2014-10-02]
Affiliated researcher
Dual channel RESOLFT nanoscopy by using fluorescent state kinetics.
Testa I, D'Este E, Urban NT, Balzarotti F, Hell SW
Nano Lett. 15 (1) 103-106 [2015-01-14; online 2014-12-02]
Ilaria Testa SciLifeLab Fellow
A high-throughput ChIP-Seq for large-scale chromatin studies.
Chabbert CD, Adjalley SH, Klaus B, ..., Pelechano V, Steinmetz LM
Mol Syst Biol 11 (1) 777 [2015-01-12; online 2015-01-12]
SciLifeLab Fellow Vicent Pelechano
The origin and evolution of maize in the Southwestern United States.
da Fonseca RR, Smith BD, Wales N, ..., Ross-Ibarra J, Gilbert MT
Nat Plants 1 (-) 14003 [2015-01-08; online 2015-01-08]
Affiliated researcher
Multiscale simulations of human telomeric G-quadruplex DNA.
Rebič M, Mocci F, Laaksonen A, Uličný J
J Phys Chem B 119 (1) 105-113 [2015-01-08; online 2014-12-17]
Affiliated researcher
DCDC2 mutations cause a renal-hepatic ciliopathy by disrupting Wnt signaling.
Schueler M, Braun DA, Chandrasekar G, ..., Kere J, Hildebrandt F
Am. J. Hum. Genet. 96 (1) 81-92 [2015-01-08; online 2014-12-31]
Affiliated researcher
TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells.
Fasching L, Kapopoulou A, Sachdeva R, ..., Trono D, Jakobsson J
Cell Reports 10 (1) 20-28 [2015-01-06; online 2014-12-24]
Affiliated researcher
Mutagenesis. Smoking is associated with mosaic loss of chromosome Y.
Dumanski JP, Rasi C, Lönn M, ..., Ingelsson E, Forsberg LA
Science 347 (6217) 81-83 [2015-01-02; online 2014-12-04]
Affiliated researcher
A secretagogin locus of the mammalian hypothalamus controls stress hormone release.
Romanov RA, Alpár A, Zhang MD, ..., Hökfelt T, Harkany T
EMBO J. 34 (1) 36-54 [2015-01-02; online 2014-11-27]
Affiliated researcher
Characterization of peptide QRFP (26RFa) and its receptor from amphioxus, Branchiostoma floridae.
Xu B, Bergqvist CA, Sundström G, ..., Leprince J, Larhammar D
Gen. Comp. Endocrinol. 210 (-) 107-113 [2015-01-01; online 2014-10-25]
Affiliated researcher
The mutational landscape in pediatric acute lymphoblastic leukemia deciphered by whole genome sequencing.
Lindqvist CM, Nordlund J, Ekman D, ..., Syvänen AC, Berglund EC
Hum. Mutat. 36 (1) 118-128 [2015-01-00; online 2014-10-31]
Affiliated researcher
The Biobanking Analysis Resource Catalogue (BARCdb): a new research tool for the analysis of biobank samples.
Galli J, Oelrich J, Taussig MJ, ..., Ortega-Paino E, Landegren U
Nucleic Acids Res. 43 (Database issue) D1158-D1162 [2015-01-00; online 2014-10-21]
Affiliated researcher
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
Swerdlow DI, Preiss D, Kuchenbaecker KB, ..., Hingorani AD, Sattar N
The Lancet 385 (9965) 351-361 [2015-01-00; online 2015-01-00]
Affiliated researcher
Deregulated proliferation and differentiation in brain tumors.
Swartling FJ, Čančer M, Frantz A, Weishaupt H, Persson AI
Cell Tissue Res. 359 (1) 225-254 [2015-01-00; online 2014-11-23]
Affiliated researcher
Avoiding pitfalls in L1-regularised inference of gene networks.
Tjärnberg A, Nordling TE, Studham M, Nelander S, Sonnhammer EL
Mol Biosyst 11 (1) 287-296 [2015-01-00; online 2014-11-07]
Affiliated researcher
Pd-catalyzed C–N coupling of vinylbromides and sulfonimidamides: a facile synthesis of N′-vinylsulfonimidamides
Nandi GC, Kota SR, Wakchaure PB, ..., Naicker T, Arvidsson PI
RSC Adv. 5 (76) 62084-62090 [2015-00-00; online 2015-00-00]
Affiliated researcher
On-chip ultrasonic sample preparation for cell based assays
Iranmanesh I, Ramachandraiah H, Russom A, Wiklund M
RSC Adv. 5 (91) 74304-74311 [2015-00-00; online 2015-00-00]
Affiliated researcher
Intriguing properties of unusual silicon nanocrystals
Manzetti S, Lu T, Behzadi H, ..., Thi Le HL, Vach H
RSC Adv. 5 (95) 78192-78208 [2015-00-00; online 2015-00-00]
Affiliated researcher
Functional porous membranes from amorphous linear dendritic polyester hybrids
Mongkhontreerat S, Walter MV, Cai Y, ..., Hult A, Malkoch M
Polym. Chem. 6 (13) 2390-2395 [2015-00-00; online 2015-00-00]
Affiliated researcher
The kidney transcriptome and proteome defined by transcriptomics and antibody-based profiling.
Habuka M, Fagerberg L, Hallström BM, ..., Uhlén M, Odeberg J
PLoS ONE 9 (12) e116125 [2014-12-31; online 2014-12-31]
Affiliated researcher
Genomic, proteomic, morphological, and phylogenetic analyses of vB_EcoP_SU10, a podoviridae phage with C3 morphology.
Khan Mirzaei M, Mirzaei MK, Eriksson H, ..., Haggård-Ljungquist E, Nilsson AS
PLoS ONE 9 (12) e116294 [2014-12-31; online 2014-12-31]
Affiliated researcher
Prehistoric genomes reveal the genetic foundation and cost of horse domestication.
Schubert M, Jónsson H, Chang D, ..., Shapiro B, Orlando L
Proc. Natl. Acad. Sci. U.S.A. 111 (52) E5661-E5669 [2014-12-30; online 2014-12-15]
Affiliated researcher
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
Danielsson A, Pontén F, Fagerberg L, ..., Korsgren O, Lindskog C
PLoS ONE 9 (12) e115421 [2014-12-29; online 2014-12-29]
Affiliated researcher
The transcriptomic and proteomic landscapes of bone marrow and secondary lymphoid tissues.
Andersson S, Nilsson K, Fagerberg L, ..., Uhlen M, Asplund A
PLoS ONE 9 (12) e115911 [2014-12-26; online 2014-12-26]
Affiliated researcher
Mechanical stress downregulates MHC class I expression on human cancer cell membrane.
La Rocca R, Tallerico R, Talib Hassan A, ..., Di Fabrizio E, Carbone E
PLoS ONE 9 (12) e111758 [2014-12-26; online 2014-12-26]
Affiliated researcher
Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence.
Genovese G, Kähler AK, Handsaker RE, ..., Hultman CM, McCarroll SA
N. Engl. J. Med. 371 (26) 2477-2487 [2014-12-25; online 2014-11-26]
Affiliated researcher
Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer.
Femel J, Huijbers EJ, Saupe F, ..., Hellman L, Olsson AK
Oncotarget 5 (23) 12418-12427 [2014-12-15; online 2014-11-02]
Affiliated researcher
The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair.
Henriksson S, Rassoolzadeh H, Hedström E, ..., Helleday T, Farnebo M
Genes Dev. 28 (24) 2726-2738 [2014-12-15; online 2014-12-17]
Affiliated researcher
Rapid pulsed whole genome sequencing for comprehensive acute diagnostics of inborn errors of metabolism.
Stranneheim H, Engvall M, Naess K, ..., von Döbeln U, Wedell A
BMC Genomics 15 (-) 1090 [2014-12-11; online 2014-12-11]
Affiliated researcher
Diagnostics of primary immunodeficiency diseases: a sequencing capture approach.
Moens LN, Falk-Sörqvist E, Asplund AC, ..., Smith CI, Nilsson M
PLoS ONE 9 (12) e114901 [2014-12-11; online 2014-12-11]
Affiliated researcher
Sensitive detection of aggregated prion protein via proximity ligation.
Hammond M, Wik L, Deslys JP, ..., Landegren U, Kamali-Moghaddam M
Prion 8 (3) 261-265 [2014-12-09; online 2014-12-09]
Affiliated researcher
TGFβ receptor 1: an immune susceptibility gene in HPV-associated cancer.
Levovitz C, Chen D, Ivansson E, ..., Boffetta P, Sikora AG
Cancer Res. 74 (23) 6833-6844 [2014-12-01; online 2014-10-01]
Affiliated researcher
Toxicogenomics directory of chemically exposed human hepatocytes
Grinberg M, Stöber RM, Edlund K, ..., Rahnenführer J, Hengstler JG
Arch Toxicol 88 (12) 2261-2287 [2014-12-00; online 2014-11-16]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling.
Lindskog C, Fagerberg L, Hallström B, ..., Pontén F, Micke P
FASEB J. 28 (12) 5184-5196 [2014-12-00; online 2014-08-28]
Affiliated researcher
Large-scale metabolomic profiling identifies novel biomarkers for incident coronary heart disease.
Ganna A, Salihovic S, Sundström J, ..., Fall T, Ingelsson E
PLoS Genet 10 (12) e1004801 [2014-12-00; online 2014-12-11]
Affiliated researcher
Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides.
Borhade SR, Rosenström U, Sävmarker J, ..., Larhed M, Hallberg M
ChemistryOpen 3 (6) 256-263 [2014-12-00; online 2014-11-21]
Affiliated researcher
Efficient application of next-generation sequencing for the diagnosis of rare genetic syndromes.
Madrigal I, Alvarez-Mora MI, Karlberg O, ..., Syvänen AC, Milà M
J. Clin. Pathol. 67 (12) 1099-1103 [2014-12-00; online 2014-09-30]
Affiliated researcher
Classification aided domain reduction for high dimensional optimization
Singh P, Ferranti F, Deschrijver D, Couckuyt I, Dhaene T
- - (-) - [2014-12-00; online 2014-12-00]
Prashant Singh SciLifeLab Fellow
Community-driven development for computational biology at Sprints, Hackathons and Codefests.
Möller S, Afgan E, Banck M, ..., Katayama T, Chapman BA
BMC Bioinformatics 15 Suppl 14 (-) S7 [2014-11-27; online 2014-11-27]
Affiliated researcher
1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer.
Mayrhofer M, Kultima HG, Birgisson H, ..., Glimelius B, Isaksson A
BMC Cancer 14 (-) 872 [2014-11-24; online 2014-11-24]
Affiliated researcher
Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors
Engen K, Sävmarker J, Rosenström U, ..., Jenmalm-Jensen A, Larhed M
Org. Process Res. Dev. 18 (11) 1582-1588 [2014-11-21; online 2014-10-16]
Affiliated researcher
Constitutive activation of the ERK pathway in melanoma and skin melanocytes in Grey horses.
Jiang L, Campagne C, Sundström E, ..., Andersson L, Golovko A
BMC Cancer 14 (-) 857 [2014-11-21; online 2014-11-21]
Affiliated researcher
Single-cell transcriptomics for microbial eukaryotes.
Kolisko M, Boscaro V, Burki F, Lynn DH, Keeling PJ
Curr. Biol. 24 (22) R1081-R1082 [2014-11-17; online 2014-11-17]
Fabien Burki SciLifeLab Fellow
Structure of the large ribosomal subunit from human mitochondria
Brown A, Amunts A, Bai Xc, ..., Scheres SHW, Ramakrishnan V
Science 346 (6210) 718-722 [2014-11-07; online 2014-10-02]
Alexey Amunts SciLifeLab Fellow
Analysis of autoantibody profiles in osteoarthritis using comprehensive protein array concepts.
Henjes F, Lourido L, Ruiz-Romero C, ..., Nilsson P, Fuentes M
J. Proteome Res. 13 (11) 5218-5229 [2014-11-07; online 2014-10-09]
Affiliated researcher
Affinity proteomic profiling of plasma, cerebrospinal fluid, and brain tissue within multiple sclerosis.
Byström S, Ayoglu B, Häggmark A, ..., Nilsson P, Schwenk JM
J. Proteome Res. 13 (11) 4607-4619 [2014-11-07; online 2014-10-01]
Affiliated researcher
Detection of rotavirus using padlock probes and rolling circle amplification.
Mezger A, Öhrmalm C, Herthnek D, Blomberg J, Nilsson M
PLoS ONE 9 (11) e111874 [2014-11-04; online 2014-11-04]
Affiliated researcher
Gallium-68-labeled affibody molecule for PET imaging of PDGFRβ expression in vivo.
Strand J, Varasteh Z, Eriksson O, ..., Orlova A, Tolmachev V
Mol. Pharm. 11 (11) 3957-3964 [2014-11-03; online 2014-07-23]
Olof Eriksson SciLifeLab Fellow
Study of protein and RNA in dendritic spines using multi-isotope imaging mass spectrometry (MIMS).
Brismar H, Aperia A, Westin L, ..., Poczatek C, Lechene C
Surf Interface Anal 46 (Suppl 1) 158-160 [2014-11-01; online 2015-09-18]
Affiliated researcher
Systemic lupus erythematosus prevalence in Sweden in 2010: what do national registers say?
Simard JF, Sjöwall C, Rönnblom L, Jönsen A, Svenungsson E
Arthritis Care Res (Hoboken) 66 (11) 1710-1717 [2014-11-00; online 2014-04-24]
Affiliated researcher
Silenced B-cell receptor response to autoantigen in a poor-prognostic subset of chronic lymphocytic leukemia.
Bergh AC, Evaldsson C, Pedersen LB, ..., Rosenquist R, Rosén A
Haematologica 99 (11) 1722-1730 [2014-11-00; online 2014-08-01]
Affiliated researcher
Polymeric Smart Coating Strategy for Titanium Implants
Berts I, Ossipov D, Fragneto G, Frisk A, Rennie AR
Adv. Eng. Mater. 16 (11) 1340-1350 [2014-11-00; online 2014-04-01]
Affiliated researcher
Parallel barcoding of antibodies for DNA-assisted proteomics.
Dezfouli M, Vickovic S, Iglesias MJ, Schwenk JM, Ahmadian A
Proteomics 14 (21-22) 2432-2436 [2014-11-00; online 2014-09-30]
Affiliated researcher Sanja Vickovic SciLifeLab Fellow
Influence of persistent organic pollutants on oxidative stress in population-based samples.
Kumar J, Monica Lind P, Salihovic S, ..., Lind L, Ingelsson E
Chemosphere 114 (-) 303-309 [2014-11-00; online 2014-06-02]
Affiliated researcher
Evolution reveals a glutathione-dependent mechanism of 3-hydroxypropionic acid tolerance.
Kildegaard KR, Hallström BM, Blicher TH, ..., Nielsen J, Borodina I
Metab. Eng. 26 (-) 57-66 [2014-11-00; online 2014-09-28]
Affiliated researcher
Defining the role of common variation in the genomic and biological architecture of adult human height.
Wood AR, Esko T, Yang J, ..., Hirschhorn JN, Frayling TM
Nat. Genet. 46 (11) 1173-1186 [2014-11-00; online 2014-10-05]
Affiliated researcher
Challenges in computational studies of enzyme structure, function and dynamics.
Carvalho AT, Barrozo A, Doron D, ..., Major DT, Kamerlin SC
J. Mol. Graph. Model. 54 (-) 62-79 [2014-11-00; online 2014-09-28]
Affiliated researcher
Binning metagenomic contigs by coverage and composition.
Alneberg J, Bjarnason BS, de Bruijn I, ..., Andersson AF, Quince C
Nat. Methods 11 (11) 1144-1146 [2014-11-00; online 2014-09-14]
Affiliated researcher
Abolished InsP3R2 function inhibits sweat secretion in both humans and mice.
Klar J, Hisatsune C, Baig SM, ..., Mikoshiba K, Dahl N
J. Clin. Invest. 124 (11) 4773-4780 [2014-11-00; online 2014-10-20]
Affiliated researcher
Designing a multimer allergen for diagnosis and immunotherapy of dog allergic patients.
Nilsson OB, Neimert-Andersson T, Bronge M, ..., van Hage M, Grönlund H
PLoS ONE 9 (10) e111041 [2014-10-29; online 2014-10-29]
Affiliated researcher
Ligand-based target prediction with signature fingerprints.
Alvarsson J, Eklund M, Engkvist O, ..., Wikberg JE, Noeske T
J Chem Inf Model 54 (10) 2647-2653 [2014-10-27; online 2014-10-03]
Affiliated researcher
Structure and mechanism of Zn2+-transporting P-type ATPases.
Wang K, Sitsel O, Meloni G, ..., Nissen P, Gourdon P
Nature 514 (7523) 518-522 [2014-10-23; online 2014-08-17]
Affiliated researcher
Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs.
Adoue V, Schiavi A, Light N, ..., Syvänen AC, Pastinen T
Mol Syst Biol 10 (-) 754 [2014-10-16; online 2014-10-16]
Affiliated researcher
Crux: rapid open source protein tandem mass spectrometry analysis.
McIlwain S, Tamura K, Kertesz-Farkas A, ..., MacCoss MJ, Noble WS
J. Proteome Res. 13 (10) 4488-4491 [2014-10-03; online 2014-09-09]
Affiliated researcher
Biofuels. Altered sterol composition renders yeast thermotolerant.
Caspeta L, Chen Y, Ghiaci P, ..., Petranovic D, Nielsen J
Science 346 (6205) 75-78 [2014-10-03; online 2014-10-02]
Affiliated researcher
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
Perry JR, Day F, Elks CE, ..., Murabito JM, Ong KK
Nature 514 (7520) 92-97 [2014-10-02; online 2014-07-23]
Affiliated researcher
Specific targeting of human caspases using designed ankyrin repeat proteins.
Flütsch A, Schroeder T, Barandun J, ..., Bühlmann M, Grütter MG
Biol. Chem. 395 (10) 1243-1252 [2014-10-00; online 2014-08-26]
Jonas Barandun SciLifeLab Fellow
Phenotype standardization for statin-induced myotoxicity.
Alfirevic A, Neely D, Armitage J, ..., Palmer CN, Pirmohamed M
Clin. Pharmacol. Ther. 96 (4) 470-476 [2014-10-00; online 2014-06-04]
Affiliated researcher
Effect of cardiovascular drugs on mortality in atrial fibrillation and chronic heart failure.
Wändell P, Carlsson AC, Sundquist J, ..., Bottai M, Sundquist K
Scand. Cardiovasc. J. 48 (5) 291-298 [2014-10-00; online 2014-08-06]
Affiliated researcher
Design of a general-purpose European compound screening library for EU-OPENSCREEN.
Horvath D, Lisurek M, Rupp B, ..., Quintana J, Frank R
ChemMedChem 9 (10) 2309-2326 [2014-10-00; online 2014-07-15]
Affiliated researcher
BRCA2 and RAD51 promote double-strand break formation and cell death in response to gemcitabine.
Jones RM, Kotsantis P, Stewart GS, Groth P, Petermann E
Mol. Cancer Ther. 13 (10) 2412-2421 [2014-10-00; online 2014-07-22]
Affiliated researcher
The Chironomus tentans genome sequence and the organization of the Balbiani ring genes.
Kutsenko A, Svensson T, Nystedt B, ..., Visa N, Wieslander L
BMC Genomics 15 (-) 819 [2014-09-27; online 2014-09-27]
Affiliated researcher
Glial origin of mesenchymal stem cells in a tooth model system.
Kaukua N, Shahidi MK, Konstantinidou C, ..., Fried K, Adameyko I
Nature 513 (7519) 551-554 [2014-09-25; online 2014-07-27]
Affiliated researcher
The genomic substrate for adaptive radiation in African cichlid fish.
Brawand D, Wagner CE, Li YI, ..., Seehausen O, Di Palma F
Nature 513 (7518) 375-381 [2014-09-18; online 2014-09-03]
Affiliated researcher
A universal approach to prepare reagents for DNA-assisted protein analysis.
Yan J, Gu GJ, Jost C, ..., Landegren U, Kamali-Moghaddam M
PLoS ONE 9 (9) e108061 [2014-09-18; online 2014-09-18]
Affiliated researcher
Spontaneous transmembrane helix insertion thermodynamically mimics translocon-guided insertion.
Ulmschneider MB, Ulmschneider JP, Schiller N, ..., von Heijne G, White SH
Nat Commun 5 (-) 4863 [2014-09-10; online 2014-09-10]
Affiliated researcher
The prognostic value and therapeutic target role of stathmin-1 in urinary bladder cancer.
Hemdan T, Lindén M, Lind SB, ..., Malmström PU, Segersten U
Br. J. Cancer 111 (6) 1180-1187 [2014-09-09; online 2014-07-29]
Affiliated researcher
Antibiotic treatment selects for cooperative virulence of Salmonella typhimurium.
Diard M, Sellin ME, Dolowschiak T, ..., Ackermann M, Hardt WD
Curr. Biol. 24 (17) 2000-2005 [2014-09-08; online 2014-08-14]
Mikael Sellin SciLifeLab Fellow
Proteomics of neuropathic pain: proteins and signaling pathways affected in a rat model.
Sui P, Watanabe H, Ossipov MH, ..., Artemenko K, Bergquist J
J. Proteome Res. 13 (9) 3957-3965 [2014-09-05; online 2014-07-28]
Affiliated researcher
PconsFold: improved contact predictions improve protein models.
Michel M, Hayat S, Skwark MJ, ..., Marks DS, Elofsson A
Bioinformatics 30 (17) i482-i488 [2014-09-01; online 2014-08-28]
Affiliated researcher
High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addison's disease patients.
Dawoodji A, Chen JL, Shepherd D, ..., Kämpe O, Cerundolo V
J. Immunol. 193 (5) 2118-2126 [2014-09-01; online 2014-07-25]
Affiliated researcher
Archaeal MBF1 binds to 30S and 70S ribosomes via its helix-turn-helix domain.
Blombach F, Launay H, Snijders AP, ..., Christodoulou J, van der Oost J
Biochem. J. 462 (2) 373-384 [2014-09-01; online 2014-05-16]
Affiliated researcher
Whole ARX gene duplication is compatible with normal intellectual development.
Popovici C, Busa T, Boute O, ..., Moncla A, Philip N
Am. J. Med. Genet. A 164A (9) 2324-2327 [2014-09-00; online 2014-07-07]
Affiliated researcher
The cellular thermal shift assay for evaluating drug target interactions in cells.
Jafari R, Almqvist H, Axelsson H, ..., Nordlund P, Martinez Molina D
Nat Protoc 9 (9) 2100-2122 [2014-09-00; online 2014-08-07]
Affiliated researcher
Point-of-care vertical flow allergen microarray assay: proof of concept.
Chinnasamy T, Segerink LI, Nystrand M, Gantelius J, Andersson Svahn H
Clin. Chem. 60 (9) 1209-1216 [2014-09-00; online 2014-07-08]
Affiliated researcher
Picocyanobacteria containing a novel pigment gene cluster dominate the brackish water Baltic Sea.
Larsson J, Celepli N, Ininbergs K, ..., Bergman B, Ekman M
ISME J 8 (9) 1892-1903 [2014-09-00; online 2014-03-13]
Affiliated researcher
Mechanisms underlying mutational signatures in human cancers.
Helleday T, Eshtad S, Nik-Zainal S
Nat. Rev. Genet. 15 (9) 585-598 [2014-09-00; online 2014-07-01]
Affiliated researcher
Investigating population history using temporal genetic differentiation.
Skoglund P, Sjödin P, Skoglund T, Lascoux M, Jakobsson M
Mol. Biol. Evol. 31 (9) 2516-2527 [2014-09-00; online 2014-06-17]
Affiliated researcher
Genome of the avirulent human-infective trypanosome--Trypanosoma rangeli.
Stoco PH, Wagner G, Talavera-Lopez C, ..., de Vasconcelos AT, Grisard EC
PLoS Negl Trop Dis 8 (9) e3176 [2014-09-00; online 2014-09-18]
Affiliated researcher
Diabetes and psychiatric illness in the total population of Stockholm.
Wändell P, Ljunggren G, Wahlström L, Carlsson AC
J Psychosom Res 77 (3) 169-173 [2014-09-00; online 2014-06-28]
Affiliated researcher
Bacterial nanoscale cultures for phenotypic multiplexed antibiotic susceptibility testing.
Weibull E, Antypas H, Kjäll P, ..., Andersson-Svahn H, Richter-Dahlfors A
J. Clin. Microbiol. 52 (9) 3310-3317 [2014-09-00; online 2014-07-02]
Affiliated researcher
Splicing in the human brain.
Zaghlool A, Ameur A, Cavelier L, Feuk L
Int. Rev. Neurobiol. 116 (-) 95-125 [2014-08-31; online 2014-08-31]
Affiliated researcher
Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication.
Carneiro M, Rubin CJ, Di Palma F, ..., Lindblad-Toh K, Andersson L
Science 345 (6200) 1074-1079 [2014-08-29; online 2014-08-30]
Affiliated researcher
Inhibition of glutamine synthetase: a potential drug target in Mycobacterium tuberculosis.
Mowbray SL, Kathiravan MK, Pandey AA, Odell LR
Molecules 19 (9) 13161-13176 [2014-08-26; online 2014-08-26]
Affiliated researcher
Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus.
Ahlgren KM, Fall T, Landegren N, ..., Lernmark Å, Kämpe O
PLoS ONE 9 (8) e105473 [2014-08-25; online 2014-08-25]
Affiliated researcher
Winter bloom of a rare betaproteobacterium in the Arctic Ocean.
Alonso-Sáez L, Zeder M, Harding T, ..., Bertilsson S, Pedrós-Alió C
Front Microbiol 5 (-) 425 [2014-08-20; online 2014-08-20]
Affiliated researcher
Understanding functional miRNA-target interactions in vivo by site-specific genome engineering.
Bassett AR, Azzam G, Wheatley L, ..., Sauka-Spengler T, Fulga TA
Nat Commun 5 (-) 4640 [2014-08-19; online 2014-08-19]
Affiliated researcher
Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.
Kilarski LL, Achterberg S, Devan WJ, ..., Bevan S, GARNET Collaborative Research Group, Wellcome Trust Case Control Consortium 2, Australian Stroke Genetic Collaborative, the METASTROKE Consortium, and the International Stroke Genetics Consortium
Neurology 83 (8) 678-685 [2014-08-19; online 2014-07-16]
Affiliated researcher
Evaluation of exome sequencing to estimate tumor burden in plasma.
Klevebring D, Neiman M, Sundling S, ..., Grönberg H, Lindberg J
PLoS ONE 9 (8) e104417 [2014-08-18; online 2014-08-18]
Affiliated researcher
Immunogenetic studies of chronic lymphocytic leukemia: revelations and speculations about ontogeny and clinical evolution.
Vardi A, Agathangelidis A, Sutton LA, ..., Rosenquist R, Stamatopoulos K
Cancer Res. 74 (16) 4211-4216 [2014-08-15; online 2014-07-29]
Affiliated researcher
The positive inside rule is stronger when followed by a transmembrane helix.
Virkki MT, Peters C, Nilsson D, ..., Wallner B, Elofsson A
J. Mol. Biol. 426 (16) 2982-2991 [2014-08-12; online 2014-06-10]
Affiliated researcher
Eye movements in ephedrone-induced parkinsonism.
Bonnet C, Rusz J, Megrelishvili M, ..., Gaymard B, Růžička E
PLoS ONE 9 (8) e104784 [2014-08-12; online 2014-08-12]
Affiliated researcher
A simple repeat polymorphism in the MITF-M promoter is a key regulator of white spotting in dogs.
Baranowska Körberg I, Sundström E, Meadows JR, ..., Andersson G, Andersson L
PLoS ONE 9 (8) e104363 [2014-08-12; online 2014-08-12]
Affiliated researcher
Urinary kidney injury molecule-1 and the risk of cardiovascular mortality in elderly men.
Carlsson AC, Larsson A, Helmersson-Karlqvist J, ..., Sundström J, Ärnlöv J
Clin J Am Soc Nephrol 9 (8) 1393-1401 [2014-08-07; online 2014-06-12]
Affiliated researcher
A whole-brain atlas of inputs to serotonergic neurons of the dorsal and median raphe nuclei.
Pollak Dorocic I, Fürth D, Xuan Y, ..., Carlén M, Meletis K
Neuron 83 (3) 663-678 [2014-08-06; online 2014-08-08]
Iskra Pollak Dorocic SciLifeLab Fellow
Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.
Madissoon E, Töhönen V, Vesterlund L, ..., Hovatta O, Kere J
PLoS ONE 9 (8) e102949 [2014-08-04; online 2014-08-04]
Affiliated researcher
HAS2 and CD44 in breast tumorigenesis.
Heldin P, Basu K, Kozlova I, Porsch H
Adv. Cancer Res. 123 (-) 211-229 [2014-08-02; online 2014-08-02]
Affiliated researcher
High- and low-throughput scoring of fat mass and body fat distribution in C. elegans.
Wählby C, Conery AL, Bray MA, ..., Carpenter AE, O'Rourke EJ
Methods 68 (3) 492-499 [2014-08-01; online 2014-04-28]
Affiliated researcher
Analysis of candidate genes for lineage-specific expression changes in humans and primates.
Lindskog C, Kuhlwilm M, Davierwala A, ..., Pääbo S, Pontén F
J. Proteome Res. 13 (8) 3596-3606 [2014-08-01; online 2014-07-15]
Affiliated researcher
Treatment of osteogenesis imperfecta in adults.
Lindahl K, Langdahl B, Ljunggren Ö, Kindmark A
Eur. J. Endocrinol. 171 (2) R79-R90 [2014-08-00; online 2014-04-23]
Affiliated researcher
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions.
Orta ML, Höglund A, Calderón-Montaño JM, ..., López-lázaro M, Helleday T
Nucleic Acids Res. 42 (14) 9108-9120 [2014-08-00; online 2014-07-29]
Affiliated researcher
Spatial control of membrane receptor function using ligand nanocalipers.
Shaw A, Lundin V, Petrova E, ..., Högberg B, Teixeira AI
Nat. Methods 11 (8) 841-846 [2014-08-00; online 2014-07-06]
Erik Benson SciLifeLab Fellow
Self-healing hybrid nanocomposites consisting of bisphosphonated hyaluronan and calcium phosphate nanoparticles.
Nejadnik MR, Yang X, Bongio M, ..., Ossipov D, Leeuwenburgh SC
Biomaterials 35 (25) 6918-6929 [2014-08-00; online 2014-05-24]
Affiliated researcher
Plasma profiling reveals three proteins associated to amyotrophic lateral sclerosis.
Häggmark A, Mikus M, Mohsenchian A, ..., Kuźma-Kozakiewicz M, Nilsson P
Ann Clin Transl Neurol 1 (8) 544-553 [2014-08-00; online 2014-07-14]
Affiliated researcher
MDM2 promotor polymorphism and disease characteristics in chronic lymphocytic leukemia: results of an individual patient data-based meta-analysis.
Benner A, Mansouri L, Rossi D, ..., Zenz T, European Research Initiative on CLL (ERIC)
Haematologica 99 (8) 1285-1291 [2014-08-00; online 2014-08-02]
Affiliated researcher
Influence of coronary artery disease-associated genetic variants on risk of venous thromboembolism.
Bruzelius M, Strawbridge RJ, Trégouët DA, ..., Odeberg J, Hamsten A
Thromb. Res. 134 (2) 426-432 [2014-08-00; online 2014-04-04]
Affiliated researcher
Identification of novel sphingolipid-binding motifs in mammalian membrane proteins.
Björkholm P, Ernst AM, Hacke M, ..., Brügger B, von Heijne G
Biochim. Biophys. Acta 1838 (8) 2066-2070 [2014-08-00; online 2014-05-02]
Affiliated researcher
A cis-regulatory mutation of PDSS2 causes silky-feather in chickens.
Feng C, Gao Y, Dorshorst B, ..., Hu X, Li N
PLoS Genet 10 (8) e1004576 [2014-08-00; online 2014-08-28]
Affiliated researcher
Nuclease-assisted suppression of human DNA background in sepsis.
Song Y, Giske CG, Gille-Johnson P, ..., Lundeberg J, Gyarmati P
PLoS ONE 9 (7) e103610 [2014-07-30; online 2014-07-30]
Affiliated researcher
On-chip detection of rolling circle amplified DNA molecules from Bacillus globigii spores and Vibrio cholerae.
Østerberg FW, Rizzi G, Donolato M, ..., Svedlindh P, Hansen MF
Small 10 (14) 2877-2882 [2014-07-23; online 2014-03-10]
Affiliated researcher
The molecular mode of action of the active component of chili pepper
Elokely K, Palovcak E, Delemotte L, Carnevale V, Klein M
Planta Med 80 (10) - [2014-07-14; online 2014-07-14]
Lucie Delemotte SciLifeLab Fellow
Proline N-oxides: modulators of the 3D conformation of linear peptides through "NO-turns".
Farahani MD, Honarparvar B, Albericio F, ..., Arvidsson PI, Kruger HG
Org. Biomol. Chem. 12 (25) 4479-4490 [2014-07-07; online 2014-05-23]
Affiliated researcher
Increased C-telopeptide cross-linking of tendon type I collagen in fibromodulin-deficient mice.
Kalamajski S, Liu C, Tillgren V, ..., Weis M, Eyre DR
J. Biol. Chem. 289 (27) 18873-18879 [2014-07-04; online 2014-05-21]
Affiliated researcher
Transcriptome analysis reveals signature of adaptation to landscape fragmentation.
Somervuo P, Kvist J, Ikonen S, ..., Ahola V, Hanski I
PLoS ONE 9 (7) e101467 [2014-07-02; online 2014-07-02]
Affiliated researcher
Peptide-independent stabilization of MHC class I molecules breaches cellular quality control.
Hein Z, Uchtenhagen H, Abualrous ET, ..., Springer S, Boulanger D
J. Cell. Sci. 127 (Pt 13) 2885-2897 [2014-07-01; online 2014-05-07]
Affiliated researcher
l-Proline organocatalyzed Michael synthesis of monobactam and carbapenem β-lactam cores
Khanyase S, Naicker T, Maguire GEM, ..., Arvidsson PI, Govender T
Tetrahedron: Asymmetry 25 (13-14) 969-973 [2014-07-00; online 2014-07-00]
Affiliated researcher
SIRT1 promoter polymorphisms as clinical modifiers on systemic lupus erythematosus.
Consiglio CR, Juliana da Silveira S, Monticielo OA, ..., Brenol JC, Chies JA
Mol. Biol. Rep. 41 (7) 4233-4239 [2014-07-00; online 2014-02-26]
Camila Consiglio DDLS Fellow
Pre-clinical evaluation of [(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4 for imaging of insulinoma.
Selvaraju RK, Velikyan I, Asplund V, ..., Korsgren O, Eriksson O
Nucl. Med. Biol. 41 (6) 471-476 [2014-07-00; online 2014-03-29]
Olof Eriksson SciLifeLab Fellow
Microfluidics for nano-pathophysiology.
Sato K, Sasaki N, Svahn HA, Sato K
Adv. Drug Deliv. Rev. 74 (-) 115-121 [2014-07-00; online 2013-08-31]
Affiliated researcher
Improving ITS sequence data for identification of plant pathogenic fungi
Nilsson RH, Hyde KD, Pawłowska J, ..., Kõljalg U, Abarenkov K
Fungal Diversity 67 (1) 11-19 [2014-07-00; online 2014-05-15]
DDLS Fellow Johan Bengtsson-Palme
Hijacking of host calreticulin is required for the white spot syndrome virus replication cycle.
Watthanasurorot A, Guo E, Tharntada S, ..., Söderhäll K, Söderhäll I
J. Virol. 88 (14) 8116-8128 [2014-07-00; online 2014-05-07]
Affiliated researcher
Genome-wide association analysis identifies six new loci associated with forced vital capacity.
Loth DW, Soler Artigas M, Gharib SA, ..., Tobin MD, London SJ
Nat. Genet. 46 (7) 669-677 [2014-07-00; online 2014-06-15]
Affiliated researcher
Forensic informativity of ~3000 bp of coding sequence of domestic dog mtDNA.
Angleby H, Oskarsson M, Pang J, ..., Webb KM, Savolainen P
J. Forensic Sci. 59 (4) 898-908 [2014-07-00; online 2014-05-11]
Affiliated researcher
Folding of Aquaporin 1: multiple evidence that helix 3 can shift out of the membrane core.
Virkki MT, Agrawal N, Edsbäcker E, ..., Elofsson A, Kauko A
Protein Sci. 23 (7) 981-992 [2014-07-00; online 2014-05-14]
Affiliated researcher
Deleterious mutation in FDX1L gene is associated with a novel mitochondrial muscle myopathy.
Spiegel R, Saada A, Halvardson J, ..., Feuk L, Elpeleg O
Eur. J. Hum. Genet. 22 (7) 902-906 [2014-07-00; online 2013-11-27]
Affiliated researcher
CXCR4 Antagonists: A Screening Strategy for Identification of Functionally Selective Ligands.
Castaldo C, Benicchi T, Otrocka M, ..., Varrone M, Porcari V
J Biomol Screen 19 (6) 859-869 [2014-07-00; online 2014-03-14]
Affiliated researcher
Affinity proteomics within rare diseases: a BIO-NMD study for blood biomarkers of muscular dystrophies.
Ayoglu B, Chaouch A, Lochmüller H, ..., Nilsson P, Al-Khalili Szigyarto C
EMBO Mol Med 6 (7) 918-936 [2014-07-00; online 2014-06-13]
Affiliated researcher
A constrained multi-objective surrogate-based optimization algorithm
Singh P, Couckuyt I, Ferranti F, Dhaene T
- - (-) - [2014-07-00; online 2014-07-00]
Prashant Singh SciLifeLab Fellow
A universal genomic coordinate translator for comparative genomics.
Zamani N, Sundström G, Meadows JR, ..., Haas BJ, Grabherr MG
BMC Bioinformatics 15 (-) 227 [2014-06-30; online 2014-06-30]
Affiliated researcher
Large tilts in transmembrane helices can be induced during tertiary structure formation.
Virkki M, Boekel C, Illergård K, ..., von Heijne G, Nilsson I
J. Mol. Biol. 426 (13) 2529-2538 [2014-06-26; online 2014-04-30]
Affiliated researcher
Fabrication and functionalization of PCB gold electrodes suitable for DNA-based electrochemical sensing.
Salvo P, Henry OY, Dhaenens K, ..., O'Sullivan CK, Vanfleteren J
Biomed Mater Eng 24 (4) 1705-1714 [2014-06-21; online 2014-06-21]
Affiliated researcher
The genomic landscape underlying phenotypic integrity in the face of gene flow in crows.
Poelstra JW, Vijay N, Bossu CM, ..., Grabherr MG, Wolf JB
Science 344 (6190) 1410-1414 [2014-06-20; online 2014-06-21]
Affiliated researcher
Rational design and validation of a Tip60 histone acetyltransferase inhibitor.
Gao C, Bourke E, Scobie M, ..., Lowndes NF, Brown JA
Sci Rep 4 (-) 5372 [2014-06-20; online 2014-06-20]
Affiliated researcher
Functional association networks as priors for gene regulatory network inference.
Studham ME, Tjärnberg A, Nordling TE, Nelander S, Sonnhammer EL
Bioinformatics 30 (12) i130-i138 [2014-06-15; online 2014-06-17]
Affiliated researcher
Boosting of HIV-1 neutralizing antibody responses by a distally related retroviral envelope protein.
Uchtenhagen H, Schiffner T, Bowles E, ..., Stewart-Jones G, Spetz AL
J. Immunol. 192 (12) 5802-5812 [2014-06-15; online 2014-05-14]
Affiliated researcher
Tyrosine phosphorylation profiling via in situ proximity ligation assay.
Elfineh L, Classon C, Asplund A, ..., Kamali-Moghaddam M, Lind SB
BMC Cancer 14 (-) 435 [2014-06-13; online 2014-06-13]
Affiliated researcher
Analysis of structural diversity in wolf-like canids reveals post-domestication variants.
Ramirez O, Olalde I, Berglund J, ..., Vilà C, Marques-Bonet T
BMC Genomics 15 (-) 465 [2014-06-12; online 2014-06-12]
Affiliated researcher
QUANTIFICATION OF THE 3D MORPHOLOGY OF THE BONE CELL NETWORK FROM SYNCHROTRON MICRO-CT IMAGES
Dong P, Pacureanu A, Zuluaga MA, ..., Grimal Q, Peyrin F
Image Anal Stereol 33 (2) 157 [2014-06-07; online 2014-06-07]
Affiliated researcher
Role of Na,K-ATPase α1 and α2 isoforms in the support of astrocyte glutamate uptake.
Illarionova NB, Illarionava NB, Brismar H, Aperia A, Gunnarson E
PLoS ONE 9 (6) e98469 [2014-06-05; online 2014-06-05]
Affiliated researcher
Early B cell factor 1 regulates adipocyte morphology and lipolysis in white adipose tissue.
Gao H, Mejhert N, Fretz JA, ..., Horowitz MC, Arner P
Cell Metab. 19 (6) 981-992 [2014-06-03; online 2014-05-22]
Affiliated researcher
Scanning inverse fluorescence correlation spectroscopy.
Bergstrand J, Rönnlund D, Widengren J, Wennmalm S
Opt Express 22 (11) 13073-13090 [2014-06-02; online 2014-06-13]
Affiliated researcher
The human testis-specific proteome defined by transcriptomics and antibody-based profiling.
Djureinovic D, Fagerberg L, Hallström B, ..., Uhlén M, Pontén F
Mol. Hum. Reprod. 20 (6) 476-488 [2014-06-00; online 2014-03-05]
Affiliated researcher
The age and genomic integrity of neurons after cortical stroke in humans.
Huttner HB, Bergmann O, Salehpour M, ..., Lundeberg J, Frisén J
Nat. Neurosci. 17 (6) 801-803 [2014-06-00; online 2014-04-20]
Affiliated researcher
SpliceVista, a tool for splice variant identification and visualization in shotgun proteomics data.
Zhu Y, Hultin-Rosenberg L, Forshed J, ..., Orre LM, Lehtiö J
Mol. Cell Proteomics 13 (6) 1552-1562 [2014-06-00; online 2014-04-01]
Affiliated researcher
Soluble TNF receptors and kidney dysfunction in the elderly.
Carlsson AC, Larsson TE, Helmersson-Karlqvist J, ..., Lind L, Ärnlöv J
J. Am. Soc. Nephrol. 25 (6) 1313-1320 [2014-06-00; online 2014-02-07]
Affiliated researcher
Nucleosome regulatory dynamics in response to TGFβ.
Enroth S, Andersson R, Bysani M, ..., Komorowski J, Wadelius C
Nucleic Acids Res. 42 (11) 6921-6934 [2014-06-00; online 2014-04-25]
Affiliated researcher
Molecular evolution of GPCRs: Somatostatin/urotensin II receptors.
Tostivint H, Ocampo Daza D, Bergqvist CA, ..., Lihrmann I, Larhammar D
J. Mol. Endocrinol. 52 (3) T61-T86 [2014-06-00; online 2014-04-16]
Affiliated researcher
Low gut microbiota diversity in early infancy precedes asthma at school age.
Abrahamsson TR, Jakobsson HE, Andersson AF, ..., Engstrand L, Jenmalm MC
Clin. Exp. Allergy 44 (6) 842-850 [2014-06-00; online 2013-12-18]
Affiliated researcher
Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.
Dimas AS, Lagou V, Barker A, ..., Prokopenko I, MAGIC Investigators
Diabetes 63 (6) 2158-2171 [2014-06-00; online 2013-12-02]
Affiliated researcher
DNA methylation and body-mass index: a genome-wide analysis
Dick KJ, Nelson CP, Tsaprouni L, ..., Deloukas P, Samani NJ
The Lancet 383 (9933) 1990-1998 [2014-06-00; online 2014-06-00]
Affiliated researcher
Characterization of Leukocyte Formin FMNL1 Expression in Human Tissues.
Gardberg M, Heuser VD, Iljin K, ..., Uhlen M, Carpén O
J. Histochem. Cytochem. 62 (6) 460-470 [2014-06-00; online 2014-04-03]
Affiliated researcher
Why have small multidrug resistance proteins not evolved into fused, internally duplicated structures?
Lloris-Garcerá P, Seppälä S, Slusky JS, Rapp M, von Heijne G
J. Mol. Biol. 426 (11) 2246-2254 [2014-05-29; online 2014-03-30]
Affiliated researcher
Trait-based approaches for understanding microbial biodiversity and ecosystem functioning.
Krause S, Le Roux X, Niklaus PA, ..., Philippot L, Bodelier PL
Front Microbiol 5 (-) 251 [2014-05-27; online 2014-05-27]
Affiliated researcher
Private haplotypes can reveal local adaptation.
Sjöstrand AE, Sjödin P, Jakobsson M
BMC Genet. 15 (-) 61 [2014-05-22; online 2014-05-22]
Affiliated researcher
A lateral flow paper microarray for rapid allergy point of care diagnostics.
Chinnasamy T, Segerink LI, Nystrand M, Gantelius J, Svahn HA
Analyst 139 (10) 2348-2354 [2014-05-21; online 2014-04-03]
Affiliated researcher
Genomic diversity and admixture differs for Stone-Age Scandinavian foragers and farmers.
Skoglund P, Malmström H, Omrak A, ..., Götherström A, Jakobsson M
Science 344 (6185) 747-750 [2014-05-16; online 2014-04-24]
Affiliated researcher
Proteomics analysis of melanoma metastases: association between S100A13 expression and chemotherapy resistance.
Azimi A, Pernemalm M, Frostvik Stolt M, ..., Egyházi Brage S, Hertzman Johansson C
Br. J. Cancer 110 (10) 2489-2495 [2014-05-13; online 2014-04-10]
Affiliated researcher
Chemical strategies for development of ATR inhibitors.
Llona-Minguez S, Höglund A, Jacques SA, Koolmeister T, Helleday T
Expert Rev Mol Med 16 (-) e10 [2014-05-09; online 2014-05-09]
Affiliated researcher
Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.
Turunen M, Spaeth JM, Keskitalo S, ..., Taipale J, Boyer TG
Cell Reports 7 (3) 654-660 [2014-05-08; online 2014-04-18]
Affiliated researcher
DNA mismatch repair gene MSH6 implicated in determining age at natural menopause.
Perry JR, Hsu YH, Chasman DI, ..., Karasik D, Murray A
Hum. Mol. Genet. 23 (9) 2490-2497 [2014-05-01; online 2013-12-19]
Affiliated researcher
Quality control and conduct of genome-wide association meta-analyses.
Winkler TW, Day FR, Croteau-Chonka DC, ..., Loos RJ, Genetic Investigation of Anthropometric Traits (GIANT) Consortium
Nat Protoc 9 (5) 1192-1212 [2014-05-00; online 2014-04-24]
Affiliated researcher
Protein biomarker validation via proximity ligation assays.
Blokzijl A, Nong R, Darmanis S, ..., Landegren U, Kamali-Moghaddam M
Biochim. Biophys. Acta 1844 (5) 933-939 [2014-05-00; online 2013-08-07]
Affiliated researcher
Pharmacokinetics for topically applied caffeine in the rat.
Kronschläger M, Forsman E, Yu Z, ..., Bergquist J, Söderberg P
Exp. Eye Res. 122 (-) 94-101 [2014-05-00; online 2014-04-01]
Affiliated researcher
Inflammatory biomarker pentraxin 3 (PTX3) in relation to obesity, body fat depots and weight loss.
Witasp A, Carrero JJ, Michaëlsson K, ..., Stenvinkel P, Arnlöv J
Obesity (Silver Spring) 22 (5) 1373-1379 [2014-05-00; online 2014-01-25]
Affiliated researcher
Increased urinary cystatin C indicated higher risk of cardiovascular death in a community cohort.
Helmersson-Karlqvist J, Ärnlöv J, Carlsson AC, Härmä J, Larsson A
Atherosclerosis 234 (1) 108-113 [2014-05-00; online 2014-02-28]
Affiliated researcher
GRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma.
Nord KH, Lilljebjörn H, Vezzi F, ..., Hogendoorn PC, Szuhai K
Nat. Genet. 46 (5) 474-477 [2014-05-00; online 2014-03-23]
Affiliated researcher
Engineering synergy in biotechnology.
Nielsen J, Fussenegger M, Keasling J, ..., Prather K, Palsson B
Nat. Chem. Biol. 10 (5) 319-322 [2014-05-00; online 2014-04-20]
Affiliated researcher
Dean flow-coupled inertial focusing in curved channels.
Ramachandraiah H, Ardabili S, Faridi AM, ..., Mårtensson G, Russom A
Biomicrofluidics 8 (3) 034117 [2014-05-00; online 2014-06-24]
Affiliated researcher
CCL2 mediates anti-fibrotic effects in human fibroblasts independently of CCR2.
Kalderén C, Stadler C, Forsgren M, ..., Sydow-Bäckman M, Svensson Gelius S
Int. Immunopharmacol. 20 (1) 66-73 [2014-05-00; online 2014-02-26]
Affiliated researcher
Assessing the maximum contribution from ancient populations.
Sjödin P, Skoglund P, Jakobsson M
Mol. Biol. Evol. 31 (5) 1248-1260 [2014-05-00; online 2014-02-03]
Affiliated researcher
A Bayesian method for analyzing lateral gene transfer.
Sjöstrand J, Tofigh A, Daubin V, ..., Sennblad B, Lagergren J
Syst. Biol. 63 (3) 409-420 [2014-05-00; online 2014-02-20]
Affiliated researcher
Mutation analysis of components of the Mediator kinase module in MED12 mutation-negative uterine leiomyomas.
Mäkinen N, Heinonen HR, Sjöberg J, ..., Vahteristo P, Aaltonen LA
Br. J. Cancer 110 (9) 2246-2249 [2014-04-29; online 2014-03-18]
Affiliated researcher
Lactase persistence alleles reveal partial East African ancestry of southern African Khoe pastoralists.
Breton G, Schlebusch CM, Lombard M, ..., Soodyall H, Jakobsson M
Curr. Biol. 24 (8) 852-858 [2014-04-14; online 2014-04-03]
Affiliated researcher
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
Huber KV, Salah E, Radic B, ..., Knapp S, Superti-Furga G
Nature 508 (7495) 222-227 [2014-04-10; online 2014-04-02]
Affiliated researcher
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
Gad H, Koolmeister T, Jemth AS, ..., Berglund UW, Helleday T
Nature 508 (7495) 215-221 [2014-04-10; online 2014-04-02]
Affiliated researcher
ZBED6 modulates the transcription of myogenic genes in mouse myoblast cells.
Jiang L, Wallerman O, Younis S, ..., Andersson G, Andersson L
PLoS ONE 9 (4) e94187 [2014-04-08; online 2014-04-08]
Affiliated researcher
Evidence for the biogenesis of more than 1,000 novel human microRNAs.
Friedländer MR, Lizano E, Houben AJ, ..., Martí E, Estivill X
Genome Biol. 15 (4) R57 [2014-04-07; online 2014-04-07]
Marc Friedländer SciLifeLab Fellow
RNA- and antibody-based profiling of the human proteome with focus on chromosome 19.
Stadler C, Fagerberg L, Sivertsson Å, ..., Lundberg E, Uhlén M
J. Proteome Res. 13 (4) 2019-2027 [2014-04-04; online 2014-03-12]
Affiliated researcher
WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolism.
Sherwood V, Chaurasiya SK, Ekström EJ, ..., James P, Andersson T
Carcinogenesis 35 (4) 784-794 [2014-04-00; online 2013-11-30]
Affiliated researcher
Telomere length in circulating leukocytes is associated with lung function and disease.
Albrecht E, Sillanpää E, Karrasch S, ..., Jarvelin MR, Schulz H
Eur. Respir. J. 43 (4) 983-992 [2014-04-00; online 2013-12-05]
Affiliated researcher
Organocatalytic Mannich Reactions on a Carbapenem Core - Synthesis of Mannich Bases and Bicyclic Diazanonanes
Cele ZED, Pawar SA, Naicker T, ..., Kruger HG, Govender T
Eur. J. Org. Chem. 2014 (11) 2253-2260 [2014-04-00; online 2014-02-06]
Affiliated researcher
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.
Flannick J, Thorleifsson G, Beer NL, ..., Stefansson K, Altshuler D
Nat. Genet. 46 (4) 357-363 [2014-04-00; online 2014-03-02]
Affiliated researcher
Intracellular concentration of the tyrosine kinase inhibitor imatinib in gastrointestinal stromal tumor cells.
Berglund E, Ubhayasekera SJ, Karlsson F, ..., Bergquist J, Bränström R
Anticancer Drugs 25 (4) 415-422 [2014-04-00; online 2013-12-24]
Affiliated researcher
Interplay of overweight and insulin resistance on hypertension development.
Lytsy P, Ingelsson E, Lind L, Arnlöv J, Sundström J
J. Hypertens. 32 (4) 834-839 [2014-04-00; online 2013-12-29]
Affiliated researcher
Cell line profiling to improve monoclonal antibody production.
Kang S, Ren D, Xiao G, ..., Bondarenko PV, Deshpande R
Biotechnol. Bioeng. 111 (4) 748-760 [2014-04-00; online 2013-11-19]
Affiliated researcher
Caspase-1-like regulation of the proPO-system and role of ppA and caspase-1-like cleaved peptides from proPO in innate immunity.
Jearaphunt M, Noonin C, Jiravanichpaisal P, ..., Söderhäll I, Söderhäll K
PLoS Pathog 10 (4) e1004059 [2014-04-00; online 2014-04-10]
Affiliated researcher
Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria.
Bachmann J, Burté F, Pramana S, ..., Fernandez-Reyes D, Nilsson P
PLoS Pathog 10 (4) e1004038 [2014-04-00; online 2014-04-17]
Affiliated researcher
A central role for GRB10 in regulation of islet function in man.
Prokopenko I, Poon W, Mägi R, ..., Groop L, Lyssenko V
PLoS Genet 10 (4) e1004235 [2014-04-00; online 2014-04-03]
Affiliated researcher
Structure of the Yeast Mitochondrial Large Ribosomal Subunit
Amunts A, Brown A, Bai Xc, ..., Scheres SHW, Ramakrishnan V
Science 343 (6178) 1485-1489 [2014-03-28; online 2014-03-27]
Alexey Amunts SciLifeLab Fellow
A promoter-level mammalian expression atlas.
FANTOM Consortium and the RIKEN PMI and CLST (DGT) , Forrest AR, Kawaji H, ..., Carninci P, Hayashizaki Y
Nature 507 (7493) 462-470 [2014-03-27; online 2014-03-29]
Affiliated researcher
Nanoscopic spine localization of Norbin, an mGluR5 accessory protein.
Westin L, Reuss M, Lindskog M, Aperia A, Brismar H
BMC Neurosci 15 (-) 45 [2014-03-26; online 2014-03-26]
Affiliated researcher
Arabidopsis replacement histone variant H3.3 occupies promoters of regulated genes.
Shu H, Nakamura M, Siretskiy A, ..., Gruissem W, Hennig L
Genome Biol. 15 (4) R62 [2014-03-21; online 2014-03-21]
Affiliated researcher
Two-Color RESOLFT Nanoscopy with Green and Red Fluorescent Photochromic Proteins
Lavoie-Cardinal F, Jensen NA, Westphal V, ..., Jakobs S, Hell SW
ChemPhysChem 15 (4) 655-663 [2014-03-17; online 2014-01-21]
Ilaria Testa SciLifeLab Fellow
Sequencing degraded RNA addressed by 3' tag counting.
Sigurgeirsson B, Emanuelsson O, Lundeberg J
PLoS ONE 9 (3) e91851 [2014-03-14; online 2014-03-14]
Affiliated researcher
Production of squalene in Synechocystis sp. PCC 6803.
Englund E, Pattanaik B, Ubhayasekera SJ, ..., Bergquist J, Lindberg P
PLoS ONE 9 (3) e90270 [2014-03-13; online 2014-03-13]
Affiliated researcher
An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts.
Hoeppner MP, Lundquist A, Pirun M, ..., Lindblad-Toh K, Grabherr MG
PLoS ONE 9 (3) e91172 [2014-03-13; online 2014-03-13]
Affiliated researcher
Probing physical properties of a DNA-protein complex using nanofluidic channels.
Frykholm K, Alizadehheidari M, Fritzsche J, ..., Persson F, Westerlund F
Small 10 (5) 884-887 [2014-03-12; online 2014-01-02]
Affiliated researcher
A Generic Method for Design of Oligomer-Specific Antibodies
Brännström K, Lindhagen-Persson M, Gharibyan AL, ..., Forsgren L, Olofsson A
PLoS ONE 9 (3) e90857 [2014-03-11; online 2014-03-11]
Mikael Sellin SciLifeLab Fellow
Distinct Migration and Contact Dynamics of Resting and IL-2-Activated Human Natural Killer Cells.
Olofsson PE, Forslund E, Vanherberghen B, ..., Everhorn T, Onfelt B
Front Immunol 5 (-) 80 [2014-03-07; online 2014-03-07]
Affiliated researcher
Automated analysis of dynamic behavior of single cells in picoliter droplets.
Khorshidi MA, Rajeswari PK, Wählby C, Joensson HN, Andersson Svahn H
Lab Chip 14 (5) 931-937 [2014-03-07; online 2014-01-05]
Affiliated researcher
A chromosome-centric analysis of antibodies directed toward the human proteome using Antibodypedia.
Alm T, von Feilitzen K, Lundberg E, Sivertsson Å, Uhlén M
J. Proteome Res. 13 (3) 1669-1676 [2014-03-07; online 2014-02-17]
Affiliated researcher
Priors for X-ray in-line phase tomography of heterogeneous objects.
Langer M, Cloetens P, Hesse B, ..., Raum K, Peyrin F
Philos Trans A Math Phys Eng Sci 372 (2010) 20130129 [2014-03-06; online 2014-01-27]
Affiliated researcher
A mutation interfering with 5-lipoxygenase domain interaction leads to increased enzyme activity.
Rakonjac Ryge M, Tanabe M, Provost P, ..., Samuelsson B, Rådmark O
Arch. Biochem. Biophys. 545 (-) 179-185 [2014-03-01; online 2014-01-28]
Affiliated researcher
Melanocortin 1 Receptor-derived peptides are efficiently recognized by cytotoxic T lymphocytes from melanoma patients.
González FE, Ramírez M, Allerbring EB, ..., Achour A, Salazar-Onfray F
Immunobiology 219 (3) 189-197 [2014-03-00; online 2013-10-12]
Affiliated researcher
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium , Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium , South Asian Type 2 Diabetes (SAT2D) Consortium , ..., McCarthy MI, Morris AP
Nat. Genet. 46 (3) 234-244 [2014-03-00; online 2014-02-09]
Affiliated researcher
Differentially methylated regions in maternal and paternal uniparental disomy for chromosome 7.
Hannula-Jouppi K, Muurinen M, Lipsanen-Nyman M, ..., Greco D, Kere J
Epigenetics 9 (3) 351-365 [2014-03-00; online 2013-11-18]
Affiliated researcher
Antibody performance in western blot applications is context-dependent.
Algenäs C, Agaton C, Fagerberg L, ..., Ottosson Takanen J, Hober S
Biotechnol J 9 (3) 435-445 [2014-03-00; online 2014-01-29]
Affiliated researcher
Functional tradeoffs underpin salinity-driven divergence in microbial community composition.
Dupont CL, Larsson J, Yooseph S, ..., Venter JC, Bergman B
PLoS ONE 9 (2) e89549 [2014-02-27; online 2014-02-27]
Affiliated researcher
Gold nanowire based electrical DNA detection using rolling circle amplification.
Russell C, Welch K, Jarvius J, ..., Svedlindh P, Nilsson M
ACS Nano 8 (2) 1147-1153 [2014-02-25; online 2014-01-23]
Affiliated researcher
High-throughput screening for industrial enzyme production hosts by droplet microfluidics.
Sjostrom SL, Bai Y, Huang M, ..., Joensson HN, Andersson Svahn H
Lab Chip 14 (4) 806-813 [2014-02-21; online 2013-12-25]
Affiliated researcher
BET bromodomain inhibition of MYC-amplified medulloblastoma.
Bandopadhayay P, Bergthold G, Nguyen B, ..., Beroukhim R, Cho YJ
Clin. Cancer Res. 20 (4) 912-925 [2014-02-15; online 2013-12-02]
Affiliated researcher
The genome of a Late Pleistocene human from a Clovis burial site in western Montana.
Rasmussen M, Anzick SL, Waters MR, ..., Nielsen R, Willerslev E
Nature 506 (7487) 225-229 [2014-02-13; online 2014-02-14]
Affiliated researcher
Thiamin function, metabolism, uptake, and transport.
Manzetti S, Zhang J, van der Spoel D
Biochemistry 53 (5) 821-835 [2014-02-11; online 2014-01-31]
Affiliated researcher
Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae.
Mellroth P, Sandalova T, Kikhney A, ..., Henriques-Normark B, Achour A
MBio 5 (1) e01120-e01113 [2014-02-11; online 2014-02-11]
Affiliated researcher
Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal.
Skoglund P, Northoff BH, Shunkov MV, ..., Krause J, Jakobsson M
Proc. Natl. Acad. Sci. U.S.A. 111 (6) 2229-2234 [2014-02-11; online 2014-01-27]
Affiliated researcher
Prognostic polypeptide blood plasma biomarkers of Alzheimer's disease progression.
Yang H, Lyutvinskiy Y, Herukka SK, ..., Rutishauser D, Zubarev RA
J. Alzheimers Dis. 40 (3) 659-666 [2014-02-08; online 2014-02-08]
Affiliated researcher
Fast and accurate database searches with MS-GF+Percolator.
Granholm V, Kim S, Navarro JC, ..., Smith RD, Käll L
J. Proteome Res. 13 (2) 890-897 [2014-02-07; online 2013-12-23]
Affiliated researcher
Variation in the MC4R gene is associated with bone phenotypes in elderly Swedish women.
Garg G, Kumar J, McGuigan FE, ..., Luthman H, Åkesson K
PLoS ONE 9 (2) e88565 [2014-02-06; online 2014-02-06]
Affiliated researcher
Visual detection of DNA on paper chips.
Song Y, Gyarmati P, Araújo AC, ..., Brumer H, Ståhl PL
Anal. Chem. 86 (3) 1575-1582 [2014-02-04; online 2014-01-17]
Affiliated researcher
Removal of total organic carbon from sewage wastewater using poly(ethylenimine)-functionalized magnetic nanoparticles.
Lakshmanan R, Sanchez-Dominguez M, Matutes-Aquino JA, Wennmalm S, Kuttuva Rajarao G
Langmuir 30 (4) 1036-1044 [2014-02-04; online 2014-01-24]
Affiliated researcher
Rhizaria.
Burki F, Keeling PJ
Curr. Biol. 24 (3) R103-R107 [2014-02-03; online 2014-02-08]
Fabien Burki SciLifeLab Fellow
Differentially expressed proteins in malignant and benign adrenocortical tumors.
Kjellin H, Johansson H, Höög A, ..., Jakobsson PJ, Kjellman M
PLoS ONE 9 (2) e87951 [2014-02-03; online 2014-02-03]
Affiliated researcher
The genome of Spironucleus salmonicida highlights a fish pathogen adapted to fluctuating environments.
Xu F, Jerlström-Hultqvist J, Einarsson E, ..., Svärd SG, Andersson JO
PLoS Genet 10 (2) e1004053 [2014-02-00; online 2014-02-06]
Affiliated researcher
Subtyping of gliomas of various WHO grades by the application of immunohistochemistry.
Popova SN, Bergqvist M, Dimberg A, ..., Sooman L, Alafuzoff I
Histopathology 64 (3) 365-379 [2014-02-00; online 2013-11-05]
Affiliated researcher
Evolutionary imprint of activation: The design principles of VSDs
Palovcak E, Delemotte L, Klein ML, Carnevale V
J Gen Physiol 143 (2) 145-156 [2014-02-00; online 2014-01-27]
Lucie Delemotte SciLifeLab Fellow
Endosymbiotic Gene Transfer in Tertiary Plastid-Containing Dinoflagellates
Burki F, Imanian B, Hehenberger E, ..., Maruyama S, Keeling PJ
Eukaryotic Cell 13 (2) 246-255 [2014-02-00; online 2013-12-02]
Fabien Burki SciLifeLab Fellow
Androgen levels during adjuvant endocrine therapy in postmenopausal breast cancer patients.
Baumgart J, Nilsson K, Stavreus Evers A, ..., Bergquist J, Sundström Poromaa I
Climacteric 17 (1) 48-54 [2014-02-00; online 2013-06-28]
Affiliated researcher
An efficient and extensible format, library, and API for binary trajectory data from molecular simulations.
Lundborg M, Apostolov R, Spångberg D, ..., van der Spoel D, Lindahl E
J Comput Chem 35 (3) 260-269 [2014-01-30; online 2013-11-20]
Affiliated researcher
Silencing motifs in the Clr2 protein from fission yeast, Schizosaccharomyces pombe.
Steinhauf D, Rodriguez A, Vlachakis D, ..., Bongcam-Rudloff E, Bjerling P
PLoS ONE 9 (1) e86948 [2014-01-27; online 2014-01-27]
Affiliated researcher
Host-specificity and dynamics in bacterial communities associated with Bloom-forming freshwater phytoplankton.
Bagatini IL, Eiler A, Bertilsson S, ..., Tessarolli LP, Vieira AA
PLoS ONE 9 (1) e85950 [2014-01-20; online 2014-01-20]
Affiliated researcher
Inefficient SRP interaction with a nascent chain triggers a mRNA quality control pathway.
Karamyshev AL, Patrick AE, Karamysheva ZN, ..., Johnson AE, Thomas PJ
Cell 156 (1-2) 146-157 [2014-01-16; online 2014-01-21]
Affiliated researcher
HSF1 at a glance.
Vihervaara A, Sistonen L
J. Cell. Sci. 127 (Pt 2) 261-266 [2014-01-15; online 2014-01-15]
Anniina Vihervaara SciLifeLab Fellow
Kinks, loops, and protein folding, with protein A as an example.
Krokhotin A, Liwo A, Maisuradze GG, Niemi AJ, Scheraga HA
J Chem Phys 140 (2) 025101 [2014-01-14; online 2014-01-21]
Affiliated researcher
High rates of gene flow by pollen and seed in oak populations across Europe.
Gerber S, Chadœuf J, Gugerli F, ..., Vendramin GG, Kremer A
PLoS ONE 9 (1) e85130 [2014-01-13; online 2014-01-13]
Affiliated researcher
Assessment of whole genome amplification for sequence capture and massively parallel sequencing.
Hasmats J, Gréen H, Orear C, ..., Käller M, Lundeberg J
PLoS ONE 9 (1) e84785 [2014-01-07; online 2014-01-07]
Affiliated researcher
Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans.
Raghavan M, Skoglund P, Graf KE, ..., Jakobsson M, Willerslev E
Nature 505 (7481) 87-91 [2014-01-02; online 2013-11-20]
Affiliated researcher
Dominant mutations in GRHL3 cause Van der Woude Syndrome and disrupt oral periderm development.
Peyrard-Janvid M, Leslie EJ, Kousa YA, ..., Kere J, Schutte BC
Am. J. Hum. Genet. 94 (1) 23-32 [2014-01-02; online 2013-12-19]
Affiliated researcher
The Database of Genomic Variants: a curated collection of structural variation in the human genome.
MacDonald JR, Ziman R, Yuen RK, Feuk L, Scherer SW
Nucleic Acids Res. 42 (Database issue) D986-D992 [2014-01-00; online 2013-10-29]
Affiliated researcher
Protein biomarkers in vernix with potential to predict the development of atopic eczema in early childhood.
Holm T, Rutishauser D, Kai-Larsen Y, ..., Alm J, Scheynius A
Allergy 69 (1) 104-112 [2014-01-00; online 2013-11-11]
Affiliated researcher
Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis.
McLeod O, Silveira A, Fredrikson GN, ..., Nilsson J, Hamsten A
Atherosclerosis 232 (1) 242-248 [2014-01-00; online 2013-11-23]
Affiliated researcher
Pfam: the protein families database.
Finn RD, Bateman A, Clements J, ..., Tate J, Punta M
Nucleic Acids Res. 42 (Database issue) D222-D230 [2014-01-00; online 2013-11-27]
Affiliated researcher
Magnetic bead assisted labeling of antibodies at nanogram scale.
Dezfouli M, Vickovic S, Iglesias MJ, ..., Schwenk JM, Ahmadian A
Proteomics 14 (1) 14-18 [2014-01-00; online 2013-12-04]
Affiliated researcher Sanja Vickovic SciLifeLab Fellow
HiRIEF LC-MS enables deep proteome coverage and unbiased proteogenomics.
Branca RM, Orre LM, Johansson HJ, ..., Käll L, Lehtiö J
Nat. Methods 11 (1) 59-62 [2014-01-00; online 2013-11-17]
Affiliated researcher
FuseFISH: Robust Detection of Transcribed Gene Fusions in Single Cells
Semrau S, Crosetto N, Bienko M, ..., Chiarle R, van Oudenaarden A
Cell Reports 6 (1) 18-23 [2014-01-00; online 2014-01-00]
Magda Bienko SciLifeLab Fellow
FunCoup 3.0: database of genome-wide functional coupling networks.
Schmitt T, Ogris C, Sonnhammer EL
Nucleic Acids Res. 42 (Database issue) D380-D388 [2014-01-00; online 2013-10-31]
Affiliated researcher
Establishment and characterization of a primary and a metastatic melanoma cell line from Grey horses.
Seltenhammer MH, Sundström E, Meisslitzer-Ruppitsch C, ..., Vetterlein M, Golovko A
In Vitro Cell. Dev. Biol. Anim. 50 (1) 56-65 [2014-01-00; online 2013-08-28]
Affiliated researcher
Different mutations in PDE4D associated with developmental disorders with mirror phenotypes.
Lindstrand A, Grigelioniene G, Nilsson D, ..., Mäkitie O, Nordgren A
J. Med. Genet. 51 (1) 45-54 [2014-01-00; online 2013-11-07]
Affiliated researcher
BacMet: antibacterial biocide and metal resistance genes database.
Pal C, Bengtsson-Palme J, Rensing C, Kristiansson E, Larsson DG
Nucleic Acids Res. 42 (Database issue) D737-D743 [2014-01-00; online 2013-12-03]
DDLS Fellow Johan Bengtsson-Palme
A systematic analysis of commonly used antibodies in cancer diagnostics.
Gremel G, Bergman J, Djureinovic D, ..., Micke P, Pontén F
Histopathology 64 (2) 293-305 [2014-01-00; online 2013-11-05]
Affiliated researcher
Thermodynamics of hydronium and hydroxide surface solvation
Hub JS, Wolf MG, Caleman C, ..., Groenhof G, van der Spoel D
Chem Sci 5 (5) 1745 [2014-00-00; online 2014-00-00]
Affiliated researcher
Sensitive detection of C. parvum using near infrared emitting Ag2S@silica core–shell nanospheres
Srinivasan K, Thiruppathiraja C, Subramanian K, Dinakaran K
RSC Adv. 4 (107) 62399-62403 [2014-00-00; online 2014-00-00]
Affiliated researcher
Native and functionalized micrometre-sized cellulose capsules prepared by microfluidic flow focusing
Carrick C, Larsson PA, Brismar H, Aidun C, Wågberg L
RSC Adv. 4 (37) 19061-19067 [2014-00-00; online 2014-00-00]
Affiliated researcher
Metaxa, Overview
Bengtsson-Palme J, Hartmann M, Eriksson KM, Nilsson RH
Encyclopedia of Metagenomics - (-) 1-5 [2014-00-00; online 2014-04-16]
DDLS Fellow Johan Bengtsson-Palme
Organocatalyzed stereospecific C-C bond formation of β-lactams.
Pawar SA, Alapour S, Khanyase S, ..., Govender T, Arvidsson PI
Org. Biomol. Chem. 11 (48) 8294-8297 [2013-12-28; online 2013-11-11]
Affiliated researcher
Association of STAT4 polymorphism with severe renal insufficiency in lupus nephritis.
Bolin K, Sandling JK, Zickert A, ..., Gunnarsson I, Nordmark G
PLoS ONE 8 (12) e84450 [2013-12-27; online 2013-12-27]
Affiliated researcher
Profiling post-centrifugation delay of serum and plasma with antibody bead arrays.
Qundos U, Hong MG, Tybring G, ..., Nilsson P, Schwenk JM
J Proteomics 95 (-) 46-54 [2013-12-16; online 2013-04-28]
Affiliated researcher
SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways.
Gubanova E, Issaeva N, Gokturk C, Djureinovic T, Helleday T
Cell Cycle 12 (24) 3770-3780 [2013-12-15; online 2013-10-04]
Affiliated researcher
Bile acids modulate signaling by functional perturbation of plasma membrane domains.
Zhou Y, Maxwell KN, Sezgin E, ..., Lichtenberger LM, Levental I
J Biol Chem 288 (50) 35660-35670 [2013-12-13; online 2013-10-28]
Erdinc Sezgin SciLifeLab Fellow
The impact of nandrolone decanoate and growth hormone on biosynthesis of steroids in rats.
Grönbladh A, Johansson J, Kushnir MM, Bergquist J, Hallberg M
Steroids 78 (12-13) 1192-1199 [2013-12-11; online 2013-09-05]
Affiliated researcher
Signaling in insulin-secreting MIN6 pseudoislets and monolayer cells.
Chowdhury A, Satagopam VP, Manukyan L, ..., Bergquist J, Bergsten P
J. Proteome Res. 12 (12) 5954-5962 [2013-12-06; online 2013-09-30]
Affiliated researcher
S100A4 interacts with p53 in the nucleus and promotes p53 degradation.
Orre LM, Panizza E, Kaminskyy VO, ..., Zhivotovsky B, Lehtiö J
Oncogene 32 (49) 5531-5540 [2013-12-05; online 2013-06-10]
Affiliated researcher
Integrated molecular portrait of non-small cell lung cancers.
Lazar V, Suo C, Orear C, ..., Hansson J, Pawitan Y
BMC Med Genomics 6 (-) 53 [2013-12-03; online 2013-12-03]
Affiliated researcher
Selectivity analysis of single binder assays used in plasma protein profiling.
Neiman M, Fredolini C, Johansson H, ..., Nilsson P, Schwenk JM
Proteomics 13 (23-24) 3406-3410 [2013-12-00; online 2013-11-18]
Affiliated researcher
Protein expansion is primarily due to indels in intrinsically disordered regions.
Light S, Sagit R, Sachenkova O, Ekman D, Elofsson A
Mol. Biol. Evol. 30 (12) 2645-2653 [2013-12-00; online 2013-09-12]
Affiliated researcher
Post translational modifications in adenovirus type 2.
Bergström Lind S, Artemenko KA, Elfineh L, ..., Bergquist J, Pettersson U
Virology 447 (1-2) 104-111 [2013-12-00; online 2013-09-21]
Affiliated researcher
Novel candidate genes for 46,XY gonadal dysgenesis identified by a customized 1 M array-CGH platform.
Norling A, Lindén Hirschberg A, Iwarsson E, ..., Wedell A, Barbaro M
Eur J Med Genet 56 (12) 661-668 [2013-12-00; online 2013-09-18]
Affiliated researcher
In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics.
Grundberg I, Kiflemariam S, Mignardi M, ..., Botling J, Nilsson M
Oncotarget 4 (12) 2407-2418 [2013-12-00; online 2013-11-28]
Affiliated researcher
High expression of glycolytic and pigment proteins is associated with worse clinical outcome in stage III melanoma.
Falkenius J, Lundeberg J, Johansson H, ..., Hansson J, Egyhazi Brage S
Melanoma Res. 23 (6) 452-460 [2013-12-00; online 2013-10-17]
Affiliated researcher
Single-cell genomics reveal low recombination frequencies in freshwater bacteria of the SAR11 clade.
Zaremba-Niedzwiedzka K, Viklund J, Zhao W, ..., Stepanauskas R, Andersson SG
Genome Biol. 14 (11) R130 [2013-11-28; online 2013-11-28]
Affiliated researcher
Thermal Energy Dissipation by SiO2-Coated Plasmonic-Superparamagnetic Nanoparticles in Alternating Magnetic Fields
Sotiriou GA, Visbal-Onufrak MA, Teleki A, ..., Pratsinis SE, Rinaldi C
Chem Mater 25 (22) 4603-4612 [2013-11-26; online 2013-11-07]
Alexandra Teleki SciLifeLab Fellow
Snail depletes the tumorigenic potential of glioblastoma.
Savary K, Caglayan D, Caja L, ..., Ferletta M, Moustakas A
Oncogene 32 (47) 5409-5420 [2013-11-21; online 2013-03-25]
Affiliated researcher
Fastphylo: fast tools for phylogenetics.
Khan MA, Elias I, Sjölund E, ..., Lagergren J, Arvestad L
BMC Bioinformatics 14 (-) 334 [2013-11-20; online 2013-11-20]
Affiliated researcher
Rule-based models of the interplay between genetic and environmental factors in childhood allergy.
Bornelöv S, Sääf A, Melén E, ..., Pershagen G, Komorowski J
PLoS ONE 8 (11) e80080 [2013-11-19; online 2013-11-19]
Affiliated researcher
In vivo trp scanning of the small multidrug resistance protein EmrE confirms 3D structure models'.
Lloris-Garcerá P, Slusky JS, Seppälä S, ..., Schäfer LV, von Heijne G
J. Mol. Biol. 425 (22) 4642-4651 [2013-11-15; online 2013-08-03]
Affiliated researcher
Modulated fluorescence of colloidal quantum dots embedded in a porous alumina membrane.
Xu H, Li L, Manneberg O, ..., Brismar H, Fu Y
J Phys Chem B 117 (45) 14151-14156 [2013-11-14; online 2013-10-31]
Affiliated researcher
Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression.
Culverhouse RC, Bowes L, Breslau N, ..., Bierut LJ, 5-HTTLPR, Stress, and Depression Consortium
BMC Psychiatry 13 (-) 304 [2013-11-12; online 2013-11-12]
Erika Comasco SciLifeLab Fellow
Excap: maximization of haplotypic diversity of linked markers.
Kahles A, Sarqume F, Savolainen P, Arvestad L
PLoS ONE 8 (11) e79012 [2013-11-07; online 2013-11-07]
Affiliated researcher
β-sheet structures and dimer models of the two major tyrocidines, antimicrobial peptides from Bacillus aneurinolyticus.
Munyuki G, Jackson GE, Venter GA, ..., Bhattacharya B, van der Spoel D
Biochemistry 52 (44) 7798-7806 [2013-11-05; online 2013-10-23]
Affiliated researcher
A short C-terminal tail prevents mis-targeting of hydrophobic mitochondrial membrane proteins to the ER.
Reithinger JH, Yim C, Park K, ..., von Heijne G, Kim H
FEBS Lett. 587 (21) 3480-3486 [2013-11-01; online 2013-09-18]
Affiliated researcher
Towards a unified paradigm for sequence-based identification of fungi.
Kõljalg U, Nilsson RH, Abarenkov K, ..., Weiss M, Larsson KH
Mol. Ecol. 22 (21) 5271-5277 [2013-11-00; online 2013-09-24]
DDLS Fellow Johan Bengtsson-Palme
Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories
't Hoen PAC, Friedländer MR, Almlöf J, ..., Dermitzakis ET, Lappalainen T
Nat Biotechnol 31 (11) 1015-1022 [2013-11-00; online 2013-09-15]
Affiliated researcher Marc Friedländer SciLifeLab Fellow
Rapid and deep human proteome analysis by single-dimension shotgun proteomics.
Pirmoradian M, Budamgunta H, Chingin K, ..., Astorga-Wells J, Zubarev RA
Mol. Cell Proteomics 12 (11) 3330-3338 [2013-11-00; online 2013-07-22]
Affiliated researcher
Heritability of objectively assessed daily physical activity and sedentary behavior.
den Hoed M, Brage S, Zhao JH, ..., Wareham NJ, Loos RJ
Am. J. Clin. Nutr. 98 (5) 1317-1325 [2013-11-00; online 2013-09-18]
Affiliated researcher
Discovery and refinement of loci associated with lipid levels.
Willer CJ, Schmidt EM, Sengupta S, ..., Abecasis GR, Global Lipids Genetics Consortium
Nat. Genet. 45 (11) 1274-1283 [2013-11-00; online 2013-10-06]
Affiliated researcher
Deregulation of hyaluronan synthesis, degradation and binding promotes breast cancer.
Heldin P, Basu K, Olofsson B, ..., Kozlova I, Kahata K
J. Biochem. 154 (5) 395-408 [2013-11-00; online 2013-10-03]
Affiliated researcher
Common variants associated with plasma triglycerides and risk for coronary artery disease.
Do R, Willer CJ, Schmidt EM, ..., Neale BM, Kathiresan S
Nat. Genet. 45 (11) 1345-1352 [2013-11-00; online 2013-10-06]
Affiliated researcher
Association of genes in the NF-κB pathway with antibody-positive primary Sjögren's syndrome.
Nordmark G, Wang C, Vasaitis L, ..., Syvänen AC, UK Primary Sjögren’s Syndrome Registry
Scand. J. Immunol. 78 (5) 447-454 [2013-11-00; online 2013-08-16]
Affiliated researcher
Serglycin is implicated in the promotion of aggressive phenotype of breast cancer cells.
Korpetinou A, Skandalis SS, Moustakas A, ..., Karamanos NK, Theocharis AD
PLoS ONE 8 (10) e78157 [2013-10-31; online 2013-10-31]
Affiliated researcher
Developmental expression of IL-33 in the mouse brain.
Wicher G, Husic E, Nilsson G, Forsberg-Nilsson K
Neurosci. Lett. 555 (-) 171-176 [2013-10-25; online 2013-09-27]
Affiliated researcher
CGGBP1 phosphorylation constitutes a telomere-protection signal.
Singh U, Maturi V, Jones RE, ..., Baird DM, Westermark B
Cell Cycle 13 (1) 96-105 [2013-10-23; online 2013-10-23]
Affiliated researcher
Genome-wide probabilistic reconciliation analysis across vertebrates.
Mahmudi O, Sjöstrand J, Sennblad B, Lagergren J
BMC Bioinformatics 14 Suppl 15 (-) S10 [2013-10-15; online 2013-10-15]
Affiliated researcher
Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity.
Köpper F, Bierwirth C, Schön M, ..., Schön MP, Dobbelstein M
Proc. Natl. Acad. Sci. U.S.A. 110 (42) 16856-16861 [2013-10-15; online 2013-09-30]
Affiliated researcher
Integration of cardiac proteome biology and medicine by a specialized knowledgebase.
Zong NC, Li H, Li H, ..., Hermjakob H, Ping P
Circ. Res. 113 (9) 1043-1053 [2013-10-12; online 2013-08-21]
Affiliated researcher
Nonparametric Bayesian evaluation of differential protein quantification.
Serang O, Cansizoglu AE, Käll L, Steen H, Steen JA
J. Proteome Res. 12 (10) 4556-4565 [2013-10-04; online 2013-09-11]
Affiliated researcher
Crystal structure of Na+, K(+)-ATPase in the Na(+)-bound state.
Nyblom M, Poulsen H, Gourdon P, ..., Fedosova N, Nissen P
Science 342 (6154) 123-127 [2013-10-04; online 2013-09-19]
Affiliated researcher
Neuropsychiatric deep brain stimulation for translational neuroimaging.
Höflich A, Savli M, Comasco E, ..., Kasper S, Lanzenberger R
NeuroImage 79 (-) 30-41 [2013-10-01; online 2013-04-28]
Erika Comasco SciLifeLab Fellow
Pleiotropic effects of obesity-susceptibility loci on metabolic traits: a meta-analysis of up to 37,874 individuals.
van Vliet-Ostaptchouk JV, den Hoed M, Luan J, ..., Snieder H, Loos RJ
Diabetologia 56 (10) 2134-2146 [2013-10-00; online 2013-07-05]
Affiliated researcher
Multiplex detection of antibiotic resistance genes using padlock probes.
Barišić I, Schoenthaler S, Ke R, ..., Noehammer C, Wiesinger-Mayr H
Diagn. Microbiol. Infect. Dis. 77 (2) 118-125 [2013-10-00; online 2013-08-12]
Affiliated researcher
Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia.
Nordlund J, Bäcklin CL, Wahlberg P, ..., Lönnerholm G, Syvänen AC
Genome Biol. 14 (9) r105 [2013-09-24; online 2013-09-24]
Affiliated researcher
Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase of Trypanosoma brucei.
Lu J, Vodnala SK, Gustavsson AL, ..., Rottenberg ME, Holmgren A
J. Biol. Chem. 288 (38) 27456-27468 [2013-09-20; online 2013-07-29]
Affiliated researcher
E2F-7 couples DNA damage-dependent transcription with the DNA repair process.
Zalmas LP, Coutts AS, Helleday T, La Thangue NB
Cell Cycle 12 (18) 3037-3051 [2013-09-15; online 2013-08-20]
Affiliated researcher
Efficient TGFβ-induced epithelial-mesenchymal transition depends on hyaluronan synthase HAS2.
Porsch H, Bernert B, Mehić M, ..., Heldin CH, Heldin P
Oncogene 32 (37) 4355-4365 [2013-09-12; online 2012-10-29]
Affiliated researcher
Spatial distribution of DARPP-32 in dendritic spines.
Blom H, Rönnlund D, Scott L, ..., Aperia A, Brismar H
PLoS ONE 8 (9) e75155 [2013-09-10; online 2013-09-10]
Affiliated researcher
Gray matter is targeted in first-attack multiple sclerosis.
Schutzer SE, Angel TE, Liu T, ..., Smith RD, Coyle PK
PLoS ONE 8 (9) e66117 [2013-09-10; online 2013-09-10]
Affiliated researcher
A tosyl-activated magnetic bead cellulose as solid support for sensitive protein detection.
Yan J, Horák D, Lenfeld J, Hammond M, Kamali-Moghaddam M
J. Biotechnol. 167 (3) 235-240 [2013-09-10; online 2013-06-27]
Affiliated researcher
Transcriptome and genome sequencing uncovers functional variation in humans
Lappalainen T, Sammeth M, Friedländer MR, ..., Estivill X, Dermitzakis ET
Nature 501 (7468) 506-511 [2013-09-00; online 2013-09-15]
Affiliated researcher Marc Friedländer SciLifeLab Fellow
Perceived stress at work is associated with attenuated DHEA-S response during acute psychosocial stress.
Lennartsson AK, Theorell T, Kushnir MM, Bergquist J, Jonsdottir IH
Psychoneuroendocrinology 38 (9) 1650-1657 [2013-09-00; online 2013-02-18]
Affiliated researcher
One kilometer (1 km) electric solar wind sail tether produced automatically.
Seppänen H, Rauhala T, Kiprich S, ..., Janhunen P, Hæggström E
Rev Sci Instrum 84 (9) 095102 [2013-09-00; online 2013-10-05]
Affiliated researcher
Multilocus genetic risk scores for coronary heart disease prediction.
Ganna A, Magnusson PK, Pedersen NL, ..., Hamsten A, Ingelsson E
Arterioscler. Thromb. Vasc. Biol. 33 (9) 2267-2272 [2013-09-00; online 2013-05-16]
Affiliated researcher
In situ sequencing for RNA analysis in preserved tissue and cells.
Ke R, Mignardi M, Pacureanu A, ..., Wählby C, Nilsson M
Nat. Methods 10 (9) 857-860 [2013-09-00; online 2013-07-14]
Affiliated researcher
Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy.
Leandro-García LJ, Inglada-Pérez L, Pita G, ..., Gréen H, Rodríguez-Antona C
J. Med. Genet. 50 (9) 599-605 [2013-09-00; online 2013-06-17]
Affiliated researcher
Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations.
Wang C, Ahlford A, Järvinen TM, ..., Syvänen AC, Sandling JK
Eur. J. Hum. Genet. 21 (9) 994-999 [2013-09-00; online 2012-12-19]
Affiliated researcher
Autoantibody profiling in multiple sclerosis using arrays of human protein fragments.
Ayoglu B, Häggmark A, Khademi M, ..., Schwenk JM, Nilsson P
Mol. Cell Proteomics 12 (9) 2657-2672 [2013-09-00; online 2013-06-03]
Affiliated researcher
ABCB1 gene polymorphisms are associated with suicide in forensic autopsies.
Boiso Moreno S, Zackrisson AL, Jakobsen Falk I, ..., Hägg S, Gréen H
Pharmacogenet. Genomics 23 (9) 463-469 [2013-09-00; online 2013-07-04]
Affiliated researcher
A Convenient Microwave-Assisted Propylphosphonic Anhydride (T3P®) Mediated One-Pot Pyrazolone Synthesis
Desroses M, Jacques-Cordonnier MC, Llona-Minguez S, ..., Helleday T, Scobie M
Eur. J. Org. Chem. 2013 (26) 5879-5885 [2013-09-00; online 2013-07-29]
Affiliated researcher
The role of heat stress on the age related protein carbonylation.
Bozaykut P, Sozen E, Kaga E, ..., Bergquist J, Karademir B
J Proteomics 89 (-) 238-254 [2013-08-26; online 2013-06-26]
Affiliated researcher
DNA repair genes are selectively mutated in diffuse large B cell lymphomas.
de Miranda NF, Peng R, Georgiou K, ..., Kipling D, Pan-Hammarström Q
J. Exp. Med. 210 (9) 1729-1742 [2013-08-26; online 2013-08-19]
Affiliated researcher
Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels.
Thun GA, Imboden M, Ferrarotti I, ..., Luisetti M, Probst-Hensch NM
PLoS Genet 9 (8) e1003585 [2013-08-22; online 2013-08-22]
Affiliated researcher
Optimized nonlinear gradients for reversed-phase liquid chromatography in shotgun proteomics.
Moruz L, Pichler P, Stranzl T, Mechtler K, Käll L
Anal. Chem. 85 (16) 7777-7785 [2013-08-20; online 2013-07-24]
Affiliated researcher
Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function.
Ivanov M, Kals M, Kacevska M, ..., Milani L, Ingelman-Sundberg M
Genome Biol. 14 (8) R83 [2013-08-19; online 2013-08-19]
Affiliated researcher
Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites.
Yan J, Enge M, Whitington T, ..., Taipale M, Taipale J
Cell 154 (4) 801-813 [2013-08-15; online 2013-08-21]
Affiliated researcher
A novel method for rapid hybridization of DNA to a solid support.
Pettersson E, Ahmadian A, Ståhl PL
PLoS ONE 8 (8) e70504 [2013-08-12; online 2013-08-12]
Affiliated researcher
Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress.
Jones RM, Mortusewicz O, Afzal I, ..., Helleday T, Petermann E
Oncogene 32 (32) 3744-3753 [2013-08-08; online 2012-09-03]
Affiliated researcher
Analysis of protein interactions in situ by proximity ligation assays.
Koos B, Andersson L, Clausson CM, ..., Cane G, Söderberg O
Curr. Top. Microbiol. Immunol. 377 (-) 111-126 [2013-08-08; online 2013-08-08]
Affiliated researcher
Stabilization of the GluCl ligand-gated ion channel in the presence and absence of ivermectin.
Yoluk O, Brömstrup T, Bertaccini EJ, Trudell JR, Lindahl E
Biophys. J. 105 (3) 640-647 [2013-08-06; online 2013-08-13]
Affiliated researcher
Improved production of membrane proteins in Escherichia coli by selective codon substitutions.
Nørholm MH, Toddo S, Virkki MT, ..., von Heijne G, Daley DO
FEBS Lett. 587 (15) 2352-2358 [2013-08-02; online 2013-06-12]
Affiliated researcher
MicroRNA expression profiling in blood from fragile X-associated tremor/ataxia syndrome patients
Alvarez-Mora MI, Rodriguez-Revenga L, Madrigal I, ..., Estivill X, Milà M
- 12 (6) 595-603 [2013-08-00; online 2013-07-24]
Marc Friedländer SciLifeLab Fellow
Injection and adhesion palatoplasty: a preliminary study in a canine model.
Martínez-Álvarez C, González-Meli B, Berenguer-Froehner B, ..., Casado-Gómez I, Martínez-Sanz E
J. Surg. Res. 183 (2) 654-662 [2013-08-00; online 2013-03-22]
Affiliated researcher
Frizzled6 deficiency disrupts the differentiation process of nail development.
Cui CY, Klar J, Georgii-Heming P, ..., Schlessinger D, Dahl N
J. Invest. Dermatol. 133 (8) 1990-1997 [2013-08-00; online 2013-02-25]
Affiliated researcher
Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development.
Filipek-Górniok B, Holmborn K, Haitina T, ..., Kreuger J, Ledin J
Dev. Dyn. 242 (8) 964-975 [2013-08-00; online 2013-06-18]
Affiliated researcher
Design of a highly selective and potent class of non-planar estrogen receptor β agonists.
Sundén H, Ma JN, Hansen LK, ..., Burstein ES, Olsson R
ChemMedChem 8 (8) 1283-1294 [2013-08-00; online 2013-06-19]
Affiliated researcher
Cyclooxygenase-2
Mao Y, Poschke I, Kiessling R
Oncoimmunology 2 (8) e25157 [2013-08-00; online 2014-10-27]
SciLifeLab Fellow Yumeng Mao
Comparison of uptake mechanisms for anthracyclines in human leukemic cells.
Karim H, Bogason A, Bhuiyan H, ..., Lafolie P, Vitols S
Curr Drug Deliv 10 (4) 404-412 [2013-08-00; online 2012-10-16]
Affiliated researcher
Antibody-based profiling of cerebrospinal fluid within multiple sclerosis.
Häggmark A, Byström S, Ayoglu B, ..., Schwenk JM, Nilsson P
Proteomics 13 (15) 2256-2267 [2013-08-00; online 2013-06-25]
Affiliated researcher
A novel intellectual disability syndrome caused by GPI anchor deficiency due to homozygous mutations in PIGT.
Kvarnung M, Nilsson D, Lindstrand A, ..., Nordenskjöld M, Nordgren A
J. Med. Genet. 50 (8) 521-528 [2013-08-00; online 2013-05-01]
Affiliated researcher
Searching for synergies: matrix algebraic approaches for efficient pair screening.
Gerlee P, Schmidt L, Monsefi N, ..., Jörnsten R, Nelander S
PLoS ONE 8 (7) e68598 [2013-07-25; online 2013-07-25]
Affiliated researcher
Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer.
Johansson HJ, Sanchez BC, Mundt F, ..., Linderholm BK, Lehtiö J
Nat Commun 4 (-) 2175 [2013-07-23; online 2013-07-23]
Affiliated researcher
PCR-induced transitions are the major source of error in cleaned ultra-deep pyrosequencing data.
Brodin J, Mild M, Hedskog C, ..., Andersson B, Albert J
PLoS ONE 8 (7) e70388 [2013-07-23; online 2013-07-23]
Affiliated researcher
Arabidopsis MSI1 connects LHP1 to PRC2 complexes.
Derkacheva M, Steinbach Y, Wildhaber T, ..., Gruissem W, Hennig L
EMBO J. 32 (14) 2073-2085 [2013-07-17; online 2013-06-18]
Affiliated researcher
Improving precision of proximity ligation assay by amplified single molecule detection.
Ke R, Nong RY, Fredriksson S, Landegren U, Nilsson M
PLoS ONE 8 (7) e69813 [2013-07-16; online 2013-07-16]
Affiliated researcher
PHAISTOS: a framework for Markov chain Monte Carlo simulation and inference of protein structure.
Boomsma W, Frellsen J, Harder T, ..., Ferkinghoff-Borg J, Hamelryck T
J Comput Chem 34 (19) 1697-1705 [2013-07-15; online 2013-04-26]
Affiliated researcher
Lessons from functional analysis of genome-wide association studies.
Sur I, Tuupanen S, Whitington T, Aaltonen LA, Taipale J
Cancer Res. 73 (14) 4180-4184 [2013-07-15; online 2013-07-05]
Affiliated researcher
Structure-based Discovery of Antagonists of Nuclear Receptor LRH-1
Benod C, Carlsson J, Uthayaruban R, ..., Sablin EP, Fletterick RJ
J. Biol. Chem. 288 (27) 19830-19844 [2013-07-05; online 2013-05-10]
Jens Carlsson SciLifeLab Fellow
Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse.
Orlando L, Ginolhac A, Zhang G, ..., Wang J, Willerslev E
Nature 499 (7456) 74-78 [2013-07-04; online 2013-06-26]
Affiliated researcher
Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics.
Orsmark-Pietras C, James A, Konradsen JR, ..., Hedlin G, Melén E
Eur. Respir. J. 42 (1) 65-78 [2013-07-00; online 2012-12-06]
Affiliated researcher
Molecular profiling reveals prognostically significant subtypes of canine lymphoma.
Frantz AM, Sarver AL, Ito D, ..., O'Brien TD, Modiano JF
Vet. Pathol. 50 (4) 693-703 [2013-07-00; online 2012-11-02]
Affiliated researcher
MGclus: network clustering employing shared neighbors.
Frings O, Alexeyenko A, Sonnhammer EL
Mol Biosyst 9 (7) 1670-1675 [2013-07-00; online 2013-02-11]
Affiliated researcher
Defining, comparing, and improving iTRAQ quantification in mass spectrometry proteomics data.
Hultin-Rosenberg L, Forshed J, Branca RM, Lehtiö J, Johansson HJ
Mol. Cell Proteomics 12 (7) 2021-2031 [2013-07-00; online 2013-03-07]
Affiliated researcher
DNA methylation: the future of crime scene investigation?
Gršković B, Zrnec D, Vicković S, Popović M, Mršić G
Mol. Biol. Rep. 40 (7) 4349-4360 [2013-07-00; online 2013-05-07]
Affiliated researcher Sanja Vickovic SciLifeLab Fellow
Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy.
Karlsson H, Karlsson SC, Lindqvist AC, ..., Loskog A, Loskog SI
Cancer Gene Ther. 20 (7) 386-393 [2013-07-00; online 2013-06-21]
Affiliated researcher
Active nitrogen-fixing heterotrophic bacteria at and below the chemocline of the central Baltic Sea.
Farnelid H, Bentzon-Tilia M, Andersson AF, ..., Jürgens K, Riemann L
ISME J 7 (7) 1413-1423 [2013-07-00; online 2013-02-28]
Affiliated researcher
A facile and efficient synthesis of tetrahydro-β-carbolines
Desroses M, Koolmeister T, Jacques S, ..., Helleday T, Scobie M
Tetrahedron Letters 54 (27) 3554-3557 [2013-07-00; online 2013-07-00]
Affiliated researcher
GenPhyloData: realistic simulation of gene family evolution.
Sjöstrand J, Arvestad L, Lagergren J, Sennblad B
BMC Bioinformatics 14 (-) 209 [2013-06-27; online 2013-06-27]
Affiliated researcher
The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.
Fall T, Hägg S, Mägi R, ..., Prokopenko I, European Network for Genetic and Genomic Epidemiology (ENGAGE) consortium
PLoS Med. 10 (6) e1001474 [2013-06-25; online 2013-06-25]
Affiliated researcher
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.
Rietveld CA, Medland SE, Derringer J, ..., Cesarini D, Koellinger PD
Science 340 (6139) 1467-1471 [2013-06-21; online 2013-05-30]
Affiliated researcher
Vandetanib combined with a p38 MAPK inhibitor synergistically reduces glioblastoma cell survival.
Sooman L, Lennartsson J, Gullbo J, ..., Blomquist E, Ekman S
Med. Oncol. 30 (3) 638 [2013-06-20; online 2013-06-20]
Affiliated researcher
MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells.
Zirath H, Frenzel A, Oliynyk G, ..., Jakobsson PJ, Henriksson MA
Proc. Natl. Acad. Sci. U.S.A. 110 (25) 10258-10263 [2013-06-18; online 2013-06-03]
Affiliated researcher
Hieranoid: hierarchical orthology inference.
Schreiber F, Sonnhammer ELL
J. Mol. Biol. 425 (11) 2072-2081 [2013-06-12; online 2013-02-26]
Affiliated researcher
Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP).
Fagerberg L, Oksvold P, Skogs M, ..., von Feilitzen K, Uhlén M
J. Proteome Res. 12 (6) 2439-2448 [2013-06-07; online 2012-12-31]
Affiliated researcher
Orbitrap mass spectrometry.
Zubarev RA, Makarov A
Anal. Chem. 85 (11) 5288-5296 [2013-06-04; online 2013-05-13]
Affiliated researcher
Quantitative intact proteomics investigations of alveolar macrophages in sarcoidosis.
Silva E, Souchelnytskyi S, Kasuga K, ..., Grunewald J, Wheelock ÅM
Eur. Respir. J. 41 (6) 1331-1339 [2013-06-00; online 2012-10-11]
Affiliated researcher
Prognostic significance in breast cancer of a gene signature capturing stromal PDGF signaling.
Frings O, Augsten M, Tobin NP, ..., Ostman A, Sonnhammer EL
Am. J. Pathol. 182 (6) 2037-2047 [2013-06-00; online 2013-04-10]
Affiliated researcher
Parallel visualization of multiple protein complexes in individual cells in tumor tissue.
Leuchowius KJ, Clausson CM, Grannas K, ..., Landegren U, Söderberg O
Mol. Cell Proteomics 12 (6) 1563-1571 [2013-06-00; online 2013-02-22]
Affiliated researcher
Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse.
Geiger T, Velic A, Macek B, ..., Cox J, Mann M
Mol. Cell Proteomics 12 (6) 1709-1722 [2013-06-00; online 2013-02-22]
Affiliated researcher
Dynamin inhibitors impair endocytosis and mitogenic signaling of PDGF.
Sadowski Ł, Jastrzębski K, Kalaidzidis Y, ..., Hellberg C, Miaczynska M
Traffic 14 (6) 725-736 [2013-06-00; online 2013-03-12]
Affiliated researcher
Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility.
Wang C, Ahlford A, Laxman N, ..., Rönnblom L, Syvänen AC
Genes Immun. 14 (4) 217-222 [2013-06-00; online 2013-03-28]
Affiliated researcher
Consequences of membrane topography.
Parmryd I, Onfelt B
FEBS J. 280 (12) 2775-2784 [2013-06-00; online 2013-03-21]
Affiliated researcher
The Norway spruce genome sequence and conifer genome evolution.
Nystedt B, Street NR, Wetterbom A, ..., Lundeberg J, Jansson S
Nature 497 (7451) 579-584 [2013-05-30; online 2013-05-22]
Affiliated researcher Kristoffer Sahlin SciLifeLab Fellow
Metagenomic de novo assembly of an aquatic representative of the verrucomicrobial class Spartobacteria.
Herlemann DP, Lundin D, Labrenz M, ..., Aspeborg H, Andersson AF
MBio 4 (3) e00569-e00512 [2013-05-28; online 2013-05-28]
Affiliated researcher
Unsupervised genome-wide recognition of local relationship patterns.
Zamani N, Russell P, Lantz H, ..., Jern P, Grabherr MG
BMC Genomics 14 (-) 347 [2013-05-24; online 2013-05-24]
Affiliated researcher
Prediction of clinically relevant safety signals of nephrotoxicity through plasma metabolite profiling.
Mattes WB, Kamp HG, Fabian E, ..., Ruiz-Noppinger P, Piccoli SP
Biomed Res Int 2013 (-) 202497 [2013-05-21; online 2013-05-21]
Affiliated researcher
Adaptive mutations and replacements of virulence traits in the Escherichia coli O104:H4 outbreak population.
Guy L, Jernberg C, Arvén Norling J, ..., Engstrand L, Andersson SG
PLoS ONE 8 (5) e63027 [2013-05-10; online 2013-05-10]
Affiliated researcher
No ancient DNA damage in Actinobacteria from the Neanderthal bone.
Zaremba-Niedźwiedzka K, Andersson SG
PLoS ONE 8 (5) e62799 [2013-05-03; online 2013-05-03]
Affiliated researcher
The zebrafish orthologue of the dyslexia candidate gene DYX1C1 is essential for cilia growth and function.
Chandrasekar G, Vesterlund L, Hultenby K, Tapia-Páez I, Kere J
PLoS ONE 8 (5) e63123 [2013-05-01; online 2013-05-01]
Affiliated researcher
Genome-wide association study of susceptibility loci for cervical cancer.
Chen D, Juko-Pecirep I, Hammer J, ..., Wilander E, Gyllensten U
J. Natl. Cancer Inst. 105 (9) 624-633 [2013-05-01; online 2013-03-12]
Affiliated researcher
Alterations in the motor neuron-renshaw cell circuit in the Sod1(G93A) mouse model.
Wootz H, Fitzsimons-Kantamneni E, Larhammar M, ..., Kullander K, Alvarez FJ
J. Comp. Neurol. 521 (7) 1449-1469 [2013-05-01; online 2012-11-23]
Affiliated researcher
Optimal sparsity criteria for network inference.
Tjärnberg A, Nordling TE, Studham M, Sonnhammer EL
J. Comput. Biol. 20 (5) 398-408 [2013-05-00; online 2013-05-07]
Affiliated researcher
Membrane protein shaving with thermolysin can be used to evaluate topology predictors.
Bendz M, Skwark M, Nilsson D, ..., Käll L, Elofsson A
Proteomics 13 (9) 1467-1480 [2013-05-00; online 2013-03-21]
Affiliated researcher
Glycoprotein 130 promotes human blastocyst development in vitro.
Hambiliki F, Hanrieder J, Bergquist J, ..., Stavreus-Evers A, Wånggren K
Fertil. Steril. 99 (6) 1592-1599 [2013-05-00; online 2013-01-30]
Affiliated researcher
Global microRNA profiling of well-differentiated small intestinal neuroendocrine tumors.
Li SC, Essaghir A, Martijn C, ..., Oberg K, Giandomenico V
Mod. Pathol. 26 (5) 685-696 [2013-05-00; online 2013-01-18]
Affiliated researcher
Genome-wide analysis in German shepherd dogs reveals association of a locus on CFA 27 with atopic dermatitis.
Tengvall K, Kierczak M, Bergvall K, ..., Hedhammar Å, Lindblad-Toh K
PLoS Genet 9 (5) e1003475 [2013-05-00; online 2013-05-09]
Affiliated researcher
GAM-NGS: genomic assemblies merger for next generation sequencing.
Vicedomini R, Vezzi F, Scalabrin S, Arvestad L, Policriti A
BMC Bioinformatics 14 Suppl 7 (-) S6 [2013-04-22; online 2013-04-22]
Affiliated researcher
Detection of rifampicin resistance in Mycobacterium tuberculosis by padlock probes and magnetic nanobead-based readout.
Engström A, Zardán Gómez de la Torre T, Strømme M, Nilsson M, Herthnek D
PLoS ONE 8 (4) e62015 [2013-04-22; online 2013-04-22]
Affiliated researcher
The African coelacanth genome provides insights into tetrapod evolution.
Amemiya CT, Alföldi J, Lee AP, ..., Meyer A, Lindblad-Toh K
Nature 496 (7445) 311-316 [2013-04-18; online 2013-04-20]
Affiliated researcher
Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death.
Kirienko NV, Kirienko DR, Larkins-Ford J, ..., Ruvkun G, Ausubel FM
Cell Host Microbe 13 (4) 406-416 [2013-04-17; online 2013-04-23]
Affiliated researcher
Photoconversion of bodipy-labeled lipid analogues.
Sezgin E, Chwastek G, Aydogan G, ..., Simons K, Schwille P
Chembiochem 14 (6) 695-698 [2013-04-15; online 2013-03-19]
Erdinc Sezgin SciLifeLab Fellow
Conduction in a Biological Sodium Selective Channel
Stock L, Delemotte L, Carnevale V, Treptow W, Klein ML
J. Phys. Chem. B 117 (14) 3782-3789 [2013-04-11; online 2013-03-27]
Lucie Delemotte SciLifeLab Fellow
The ESR1 gene is associated with risk for canine mammary tumours.
Borge KS, Melin M, Rivera P, ..., Lindblad-Toh K, Lingaas F
BMC Vet. Res. 9 (-) 69 [2013-04-10; online 2013-04-10]
Affiliated researcher
European H16N3 gull influenza virus attaches to the human respiratory tract and eye.
Lindskog C, Ellström P, Olsen B, ..., Kuiken T, Jourdain E
PLoS ONE 8 (4) e60757 [2013-04-08; online 2013-04-08]
Affiliated researcher
The effects of 5-fluorouracil on the proteome of colon cancer cells.
Marin-Vicente C, Lyutvinskiy Y, Romans Fuertes P, Zubarev RA, Visa N
J. Proteome Res. 12 (4) 1969-1979 [2013-04-05; online 2013-03-21]
Affiliated researcher
Genetic determinants of dabigatran plasma levels and their relation to bleeding.
Paré G, Eriksson N, Lehr T, ..., Yusuf S, Wallentin L
Circulation 127 (13) 1404-1412 [2013-04-02; online 2013-03-06]
Affiliated researcher
RNA-binding protein QKI regulates Glial fibrillary acidic protein expression in human astrocytes.
Radomska KJ, Halvardson J, Reinius B, ..., Feuk L, Jazin E
Hum. Mol. Genet. 22 (7) 1373-1382 [2013-04-01; online 2013-01-15]
Affiliated researcher
The mitochondrial and autosomal mutation landscapes of prostate cancer.
Lindberg J, Mills IG, Klevebring D, ..., Egevad L, Grönberg H
Eur. Urol. 63 (4) 702-708 [2013-04-00; online 2012-12-05]
Affiliated researcher
Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial.
Bjarnadottir O, Romero Q, Bendahl PO, ..., Grabau D, Borgquist S
Breast Cancer Res. Treat. 138 (2) 499-508 [2013-04-00; online 2013-03-08]
Affiliated researcher
Pulmonary delivery of d-methionine is associated with an increase in ALCAR and glutathione in cochlear fluids.
Grondin Y, Cotanche DA, Manneberg O, ..., Jackson RL, Rogers RA
Hear. Res. 298 (-) 93-103 [2013-04-00; online 2013-01-04]
Affiliated researcher
Hereditary uveal melanoma: a report of a germline mutation in BAP1.
Höiom V, Edsgärd D, Helgadottir H, ..., Emanuelsson O, Hansson J
Genes Chromosomes Cancer 52 (4) 378-384 [2013-04-00; online 2013-01-23]
Affiliated researcher
Cycling of RNAs on Hfq.
Wagner EG
RNA Biol 10 (4) 619-626 [2013-04-00; online 2013-03-06]
Affiliated researcher
Comparative genomics of Wolbachia and the bacterial species concept.
Ellegaard KM, Klasson L, Näslund K, Bourtzis K, Andersson SG
PLoS Genet 9 (4) e1003381 [2013-04-00; online 2013-04-04]
Affiliated researcher
Changes in mortality and causes of death in the Swedish Down syndrome population.
Englund A, Jonsson B, Zander CS, Gustafsson J, Annerén G
Am. J. Med. Genet. A 161A (4) 642-649 [2013-04-00; online 2013-02-22]
Affiliated researcher
Genetic variants from lipid-related pathways and risk for incident myocardial infarction.
Song C, Pedersen NL, Reynolds CA, ..., Prince JA, Ingelsson E
PLoS ONE 8 (3) e60454 [2013-03-29; online 2013-03-29]
Affiliated researcher
Genome-wide mechanisms of Smad binding.
Morikawa M, Koinuma D, Miyazono K, Heldin CH
Oncogene 32 (13) 1609-1615 [2013-03-28; online 2012-05-21]
Affiliated researcher
The genomic signature of dog domestication reveals adaptation to a starch-rich diet.
Axelsson E, Ratnakumar A, Arendt ML, ..., Hedhammar A, Lindblad-Toh K
Nature 495 (7441) 360-364 [2013-03-21; online 2013-01-23]
Affiliated researcher
Identification of genetic variants influencing the human plasma proteome.
Johansson Å, Enroth S, Palmblad M, ..., Bergquist J, Gyllensten U
Proc. Natl. Acad. Sci. U.S.A. 110 (12) 4673-4678 [2013-03-19; online 2013-03-04]
Affiliated researcher
Human prostasomes express glycolytic enzymes with capacity for ATP production.
Ronquist KG, Ek B, Stavreus-Evers A, Larsson A, Ronquist G
Am. J. Physiol. Endocrinol. Metab. 304 (6) E576-E582 [2013-03-15; online 2013-01-22]
Affiliated researcher
Castration therapy results in decreased Ku70 levels in prostate cancer.
Al-Ubaidi FL, Schultz N, Loseva O, ..., Granfors T, Helleday T
Clin. Cancer Res. 19 (6) 1547-1556 [2013-03-15; online 2013-01-24]
Affiliated researcher
Hierarchical molecular tagging to resolve long continuous sequences by massively parallel sequencing.
Lundin S, Gruselius J, Nystedt B, ..., Käller M, Lundeberg J
Sci Rep 3 (-) 1186 [2013-03-09; online 2013-03-09]
Affiliated researcher
An efficient method for genome-wide polyadenylation site mapping and RNA quantification
Wilkening S, Pelechano V, Järvelin AI, ..., Benes V, Steinmetz LM
Nucleic Acids Res. 41 (5) e65-e65 [2013-03-01; online 2013-01-07]
SciLifeLab Fellow Vicent Pelechano
MALDI imaging of post-mortem human spinal cord in amyotrophic lateral sclerosis.
Hanrieder J, Ekegren T, Andersson M, Bergquist J
J. Neurochem. 124 (5) 695-707 [2013-03-00; online 2013-01-28]
Affiliated researcher
Ligand binding properties of human galanin receptors.
Jurkowski W, Yazdi S, Elofsson A
Mol. Membr. Biol. 30 (2) 206-216 [2013-03-00; online 2012-12-13]
Affiliated researcher
Fine-mapping of restless legs locus 4 (RLS4) identifies a haplotype over the SPATS2L and KCTD18 genes.
Pichler I, Schwienbacher C, Zanon A, ..., Hicks AA, Pramstaller PP
J. Mol. Neurosci. 49 (3) 600-605 [2013-03-00; online 2012-10-02]
Affiliated researcher
Replication stress links structural and numerical cancer chromosomal instability.
Burrell RA, McClelland SE, Endesfelder D, ..., Tomlinson IP, Swanton C
Nature 494 (7438) 492-496 [2013-02-28; online 2013-03-01]
Affiliated researcher
Origin and evolution of medium chain alcohol dehydrogenases.
Jörnvall H, Hedlund J, Bergman T, ..., Cederlund E, Persson B
Chem. Biol. Interact. 202 (1-3) 91-96 [2013-02-25; online 2012-11-28]
Affiliated researcher
Classification of human natural killer cells based on migration behavior and cytotoxic response.
Vanherberghen B, Olofsson PE, Forslund E, ..., Mehr R, Önfelt B
Blood 121 (8) 1326-1334 [2013-02-21; online 2013-01-03]
Affiliated researcher
Genetic susceptibility to non-necrotizing erysipelas/cellulitis.
Hannula-Jouppi K, Massinen S, Siljander T, ..., Syrjänen J, Kere J
PLoS ONE 8 (2) e56225 [2013-02-20; online 2013-02-20]
Affiliated researcher
High-throughput hyperdimensional vertebrate phenotyping.
Pardo-Martin C, Allalou A, Medina J, ..., Wählby C, Fatih Yanik M
Nat Commun 4 (-) 1467 [2013-02-14; online 2013-02-14]
Affiliated researcher
Complex inheritance of melanoma and pigmentation of coat and skin in Grey horses.
Curik I, Druml T, Seltenhammer M, ..., Andersson L, Sölkner J
PLoS Genet 9 (2) e1003248 [2013-02-07; online 2013-02-07]
Affiliated researcher
Proton Uptake and pKa Changes in the Uncoupled Asn139Cys Variant of Cytochrome c Oxidase
Johansson AL, Carlsson J, Högbom M, ..., Gennis RB, Brzezinski P
Biochemistry 52 (5) 827-836 [2013-02-05; online 2013-01-25]
Jens Carlsson SciLifeLab Fellow
Free fatty acid determination in plasma by GC-MS after conversion to Weinreb amides.
Ubhayasekera SJ, Staaf J, Forslund A, Bergsten P, Bergquist J
Anal Bioanal Chem 405 (6) 1929-1935 [2013-02-00; online 2013-01-11]
Affiliated researcher
Exome sequencing of prostate cancer supports the hypothesis of independent tumour origins.
Lindberg J, Klevebring D, Liu W, ..., Egevad L, Grönberg H
Eur. Urol. 63 (2) 347-353 [2013-02-00; online 2012-03-31]
Affiliated researcher
Adaptive filtering for enhancement of the osteocyte cell network in 3D microtomography images
Pacureanu A, Larrue A, Langer M, ..., Lafage-Proust MH, Peyrin F
IRBM 34 (1) 48-52 [2013-02-00; online 2013-02-00]
Affiliated researcher
A versatile genome-scale PCR-based pipeline for high-definition DNA FISH
Bienko M, Crosetto N, Teytelman L, ..., Itzkovitz S, van Oudenaarden A
Nat Methods 10 (2) 122-124 [2013-02-00; online 2012-12-23]
Magda Bienko SciLifeLab Fellow
Workshop on laboratory protocol standards for the Molecular Methods Database.
Klingström T, Soldatova L, Stevens R, ..., Landegren U, Bongcam-Rudloff E
N Biotechnol 30 (2) 109-113 [2013-01-25; online 2012-06-02]
Affiliated researcher
Multiplex protein detection with DNA readout via mass spectrometry.
Flanigon J, Kamali-Moghaddam M, Burbulis I, ..., Landegren U, Cantor C
N Biotechnol 30 (2) 153-158 [2013-01-25; online 2012-11-28]
Affiliated researcher
A specific and essential role for Na,K-ATPase α3 in neurons co-expressing α1 and α3.
Azarias G, Kruusmägi M, Connor S, ..., Broberger C, Aperia A
J. Biol. Chem. 288 (4) 2734-2743 [2013-01-25; online 2012-11-29]
Affiliated researcher
Target selectivity of feedforward inhibition by striatal fast-spiking interneurons.
Szydlowski SN, Pollak Dorocic I, Planert H, ..., Meletis K, Silberberg G
J. Neurosci. 33 (4) 1678-1683 [2013-01-23; online 2013-01-25]
Iskra Pollak Dorocic SciLifeLab Fellow
Statistical assessment of crosstalk enrichment between gene groups in biological networks.
McCormack T, Frings O, Alexeyenko A, Sonnhammer EL
PLoS ONE 8 (1) e54945 [2013-01-23; online 2013-01-23]
Affiliated researcher
Genomic insights into the atopic eczema-associated skin commensal yeast Malassezia sympodialis.
Gioti A, Nystedt B, Li W, ..., Heitman J, Scheynius A
MBio 4 (1) e00572-e00512 [2013-01-22; online 2013-01-22]
Affiliated researcher
A mouse mammary epithelial cell line permissive for highly efficient human adenovirus growth.
Wu C, Öberg D, Rashid A, ..., Akusjärvi G, Svensson C
Virology 435 (2) 363-371 [2013-01-20; online 2012-11-17]
Affiliated researcher
Intraperitoneal influx of neutrophils in response to IL-33 is mast cell-dependent.
Enoksson M, Möller-Westerberg C, Wicher G, ..., Lunderius-Andersson C, Nilsson G
Blood 121 (3) 530-536 [2013-01-17; online 2012-10-23]
Affiliated researcher
Possible positive selection for an arsenic-protective haplotype in humans.
Schlebusch CM, Lewis CM, Vahter M, ..., Jakobsson M, Broberg K
Environ. Health Perspect. 121 (1) 53-58 [2013-01-00; online 2012-10-16]
Affiliated researcher
MHC variability supports dog domestication from a large number of wolves: high diversity in Asia.
Niskanen AK, Hagström E, Lohi H, ..., Aspi J, Savolainen P
Heredity (Edinb) 110 (1) 80-85 [2013-01-00; online 2012-10-17]
Affiliated researcher
Latent Regulatory Potential of Human-Specific Repetitive Elements
Ward MC, Wilson MD, Barbosa-Morais NL, ..., Blencowe BJ, Odom DT
Molecular Cell 49 (2) 262-272 [2013-01-00; online 2013-01-00]
Claudia Kutter SciLifeLab Fellow
rsEGFP2 enables fast RESOLFT nanoscopy of living cells.
Grotjohann T, Testa I, Reuss M, ..., Hell SW, Jakobs S
Elife 1 (-) e00248 [2012-12-31; online 2012-12-31]
Affiliated researcher
Automated genotyping of biobank samples by multiplex amplification of insertion/deletion polymorphisms.
Mathot L, Falk-Sörqvist E, Moens L, ..., Sjöblom T, Nilsson M
PLoS ONE 7 (12) e52750 [2012-12-27; online 2012-12-27]
Affiliated researcher
Powerful identification of cis-regulatory SNPs in human primary monocytes using allele-specific gene expression.
Almlöf JC, Lundmark P, Lundmark A, ..., Cambien F, Syvänen AC
PLoS ONE 7 (12) e52260 [2012-12-26; online 2012-12-26]
Affiliated researcher
The Evolutionary Landscape of Alternative Splicing in Vertebrate Species
Barbosa-Morais NL, Irimia M, Pan Q, ..., Frey BJ, Blencowe BJ
Science 338 (6114) 1587-1593 [2012-12-21; online 2012-12-20]
Claudia Kutter SciLifeLab Fellow
Distinct modes of DNA accessibility in plant chromatin.
Shu H, Wildhaber T, Siretskiy A, Gruissem W, Hennig L
Nat Commun 3 (-) 1281 [2012-12-13; online 2012-12-13]
Affiliated researcher
A noncanonical postsynaptic transport route for a GPCR belonging to the serotonin receptor family.
Liebmann T, Kruusmägi M, Sourial-Bassillious N, ..., Brismar H, Aperia A
J. Neurosci. 32 (50) 17998-18008 [2012-12-12; online 2012-12-15]
Affiliated researcher
Visualization of custom-tailored iron oxide nanoparticles chemistry, uptake, and toxicity.
Wilkinson K, Ekstrand-Hammarström B, Ahlinder L, ..., Seisenbaeva GA, Kessler VG
Nanoscale 4 (23) 7383-7393 [2012-12-07; online 2012-10-17]
Affiliated researcher
Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.
Huang J, Sabater-Lleal M, Asselbergs FW, ..., O'Donnell CJ, Hamsten A
Blood 120 (24) 4873-4881 [2012-12-06; online 2012-09-18]
Affiliated researcher
Sonic Hedgehog-signalling patterns the developing chicken comb as revealed by exploration of the pea-comb mutation.
Boije H, Harun-Or-Rashid M, Lee YJ, ..., Andersson L, Hallböök F
PLoS ONE 7 (12) e50890 [2012-12-05; online 2012-12-05]
Affiliated researcher
In vitro oxidative inactivation of human presequence protease (hPreP).
Teixeira PF, Pinho CM, Branca RM, ..., Levine RL, Glaser E
Free Radic. Biol. Med. 53 (11) 2188-2195 [2012-12-01; online 2012-10-03]
Affiliated researcher
Minimally invasive mandibular bone augmentation using injectable hydrogels.
Martínez-Sanz E, Varghese OP, Kisiel M, ..., Ossipov DA, Hilborn J
J Tissue Eng Regen Med 6 Suppl 3 (-) s15-s23 [2012-12-00; online 2012-09-03]
Affiliated researcher
Lost in presumption: stochastic reactions in spatial models.
Mahmutovic A, Fange D, Berg OG, Elf J
Nat. Methods 9 (12) 1163-1166 [2012-12-00; online 2012-12-12]
Affiliated researcher
High-resolution mapping of linear antibody epitopes using ultrahigh-density peptide microarrays.
Buus S, Rockberg J, Forsström B, ..., Uhlen M, Schafer-Nielsen C
Mol. Cell Proteomics 11 (12) 1790-1800 [2012-12-00; online 2012-09-13]
Affiliated researcher
Evidence of a functional estrogen receptor in parathyroid adenomas.
Haglund F, Ma R, Huss M, ..., Hartman J, Larsson C
J. Clin. Endocrinol. Metab. 97 (12) 4631-4639 [2012-12-00; online 2012-09-28]
Affiliated researcher
An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations.
Vargas E, Yarov-Yarovoy V, Khalili-Araghi F, ..., Bezanilla F, Roux B
J. Gen. Physiol. 140 (6) 587-594 [2012-12-00; online 2012-11-28]
Affiliated researcher
Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs
Curtis BA, Tanifuji G, Burki F, ..., Grigoriev IV, Archibald JM
Nature 492 (7427) 59-65 [2012-12-00; online 2012-11-28]
Fabien Burki SciLifeLab Fellow
The dyslexia candidate locus on 2p12 is associated with general cognitive ability and white matter structure.
Scerri TS, Darki F, Newbury DF, ..., Klingberg T, Paracchini S
PLoS ONE 7 (11) e50321 [2012-11-28; online 2012-11-28]
Affiliated researcher
Strong signatures of selection in the domestic pig genome.
Rubin CJ, Megens HJ, Martinez Barrio A, ..., Groenen MA, Andersson L
Proc. Natl. Acad. Sci. U.S.A. 109 (48) 19529-19536 [2012-11-27; online 2012-11-14]
Affiliated researcher
Inertial microfluidics in parallel channels for high-throughput applications.
Hansson J, Karlsson JM, Haraldsson T, ..., van der Wijngaart W, Russom A
Lab Chip 12 (22) 4644-4650 [2012-11-21; online 2012-08-30]
Affiliated researcher
Population-scale sequencing reveals genetic differentiation due to local adaptation in Atlantic herring.
Lamichhaney S, Martinez Barrio A, Rafati N, ..., Ryman N, Andersson L
Proc. Natl. Acad. Sci. U.S.A. 109 (47) 19345-19350 [2012-11-20; online 2012-11-07]
Affiliated researcher
CD99 is a novel prognostic stromal marker in non-small cell lung cancer.
Edlund K, Lindskog C, Saito A, ..., Ostman A, Micke P
Int. J. Cancer 131 (10) 2264-2273 [2012-11-15; online 2012-04-24]
Affiliated researcher
Analyses of pig genomes provide insight into porcine demography and evolution.
Groenen MA, Archibald AL, Uenishi H, ..., Churcher C, Schook LB
Nature 491 (7424) 393-398 [2012-11-15; online 2012-11-16]
Affiliated researcher
The phosphoproteome of the adenovirus type 2 virion.
Bergström Lind S, Artemenko KA, Elfineh L, ..., Bergquist J, Pettersson U
Virology 433 (1) 253-261 [2012-11-10; online 2012-08-28]
Affiliated researcher
Library preparation and multiplex capture for massive parallel sequencing applications made efficient and easy.
Neiman M, Sundling S, Grönberg H, ..., Lindberg J, Klevebring D
PLoS ONE 7 (11) e48616 [2012-11-05; online 2012-11-05]
Affiliated researcher
Selective detection of bacterial layers with terahertz plasmonic antennas.
Berrier A, Schaafsma MC, Nonglaton G, Bergquist J, Rivas JG
Biomed Opt Express 3 (11) 2937-2949 [2012-11-01; online 2012-10-23]
Affiliated researcher
The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets.
Godel C, Kumar S, Koutsovoulos G, ..., Blaxter M, Mäser P
FASEB J. 26 (11) 4650-4661 [2012-11-00; online 2012-08-13]
Affiliated researcher
OLM interneurons differentially modulate CA3 and entorhinal inputs to hippocampal CA1 neurons.
Leão RN, Mikulovic S, Leão KE, ..., Tort AB, Kullander K
Nat. Neurosci. 15 (11) 1524-1530 [2012-11-00; online 2012-10-07]
Affiliated researcher
Biological aspects of postpartum depression.
Skalkidou A, Hellgren C, Comasco E, Sylvén S, Sundström Poromaa I
Womens Health (Lond) 8 (6) 659-672 [2012-11-00; online 2012-11-28]
Erika Comasco SciLifeLab Fellow
Comparison of total and cytoplasmic mRNA reveals global regulation by nuclear retention and miRNAs.
Solnestam BW, Stranneheim H, Hällman J, ..., Lundeberg J, Akan P
BMC Genomics 13 (-) 574 [2012-10-30; online 2012-10-30]
Affiliated researcher
DNA origami delivery system for cancer therapy with tunable release properties.
Zhao Y, Shaw A, Zeng X, ..., Nyström AM, Högberg B
ACS Nano 6 (10) 8684-8691 [2012-10-23; online 2012-09-13]
Erik Benson SciLifeLab Fellow
Genomic variation in seven Khoe-San groups reveals adaptation and complex African history.
Schlebusch CM, Skoglund P, Sjödin P, ..., Soodyall H, Jakobsson M
Science 338 (6105) 374-379 [2012-10-19; online 2012-09-20]
Affiliated researcher
Dual Effect of Phosphatidyl (4,5)-Bisphosphate PIP2on Shaker K+Channels
Abderemane-Ali F, Es-Salah-Lamoureux Z, Delemotte L, ..., Baró I, Loussouarn G
J. Biol. Chem. 287 (43) 36158-36167 [2012-10-19; online 2012-08-29]
Lucie Delemotte SciLifeLab Fellow
Molecular mechanism for the dual alcohol modulation of Cys-loop receptors.
Murail S, Howard RJ, Broemstrup T, ..., Trudell JR, Lindahl E
PLoS Comput Biol 8 (10) e1002710 [2012-10-04; online 2012-10-04]
Affiliated researcher
Molecular-Level Characterization of Lipid Membrane Electroporation using Linearly Rising Current
Kramar P, Delemotte L, Maček Lebar A, ..., Tarek M, Miklavčič D
J Membrane Biol 245 (10) 651-659 [2012-10-00; online 2012-08-11]
Lucie Delemotte SciLifeLab Fellow
Expansion of transducin subunit gene families in early vertebrate tetraploidizations.
Lagman D, Sundström G, Ocampo Daza D, Abalo XM, Larhammar D
Genomics 100 (4) 203-211 [2012-10-00; online 2012-07-17]
Affiliated researcher
Chemosensory proteins, major salivary factors in caterpillar mandibular glands.
Celorio-Mancera Mde L, Sundmalm SM, Vogel H, ..., Zubarev RA, Janz N
Insect Biochem. Mol. Biol. 42 (10) 796-805 [2012-10-00; online 2012-08-04]
Affiliated researcher
Application of split-green fluorescent protein for topology mapping membrane proteins in Escherichia coli.
Toddo S, Söderström B, Palombo I, ..., Nørholm MH, Daley DO
Protein Sci. 21 (10) 1571-1576 [2012-10-00; online 2012-08-21]
Affiliated researcher
Critical assessment of rhBMP-2 mediated bone induction: an in vitro and in vivo evaluation.
Kisiel M, Ventura M, Oommen OP, ..., Hilborn J, Varghese OP
J Control Release 162 (3) 646-653 [2012-09-28; online 2012-08-10]
Affiliated researcher
Elevated MARK2-dependent phosphorylation of Tau in Alzheimer's disease.
Gu GJ, Wu D, Lund H, ..., Landegren U, Kamali-Moghaddam M
J. Alzheimers Dis. 33 (3) 699-713 [2012-09-25; online 2012-09-25]
Affiliated researcher
Molecular tools for companion diagnostics.
Zieba A, Grannas K, Söderberg O, ..., Nilsson M, Landegren U
N Biotechnol 29 (6) 634-640 [2012-09-15; online 2012-05-24]
Affiliated researcher
Evolutionary conservation of the ribosomal biogenesis factor Rbm19/Mrd1: implications for function.
Kallberg Y, Segerstolpe Å, Lackmann F, Persson B, Wieslander L
PLoS ONE 7 (9) e43786 [2012-09-12; online 2012-09-12]
Affiliated researcher
Network enrichment analysis: extension of gene-set enrichment analysis to gene networks.
Alexeyenko A, Lee W, Pernemalm M, ..., Lehtiö J, Pawitan Y
BMC Bioinformatics 13 (-) 226 [2012-09-11; online 2012-09-11]
Affiliated researcher
Identification of candidate SNPs for drug induced toxicity from differentially expressed genes in associated tissues.
Hasmats J, Kupershmidt I, Rodríguez-Antona C, ..., Lundeberg J, Green H
Gene 506 (1) 62-68 [2012-09-10; online 2012-07-01]
Affiliated researcher
Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency.
Christoffersson G, Zang G, Zhuang ZW, ..., Phillipson M, Welsh M
Angiogenesis 15 (3) 469-480 [2012-09-00; online 2012-05-05]
Gustaf Christoffersson SciLifeLab Fellow
The evolution of filamin-a protein domain repeat perspective.
Light S, Sagit R, Ithychanda SS, Qin J, Elofsson A
J. Struct. Biol. 179 (3) 289-298 [2012-09-00; online 2012-03-10]
Affiliated researcher
The Revised Classification of Eukaryotes
Adl SM, Simpson AGB, Lane CE, ..., Smirnov A, Spiegel FW
J. Eukaryot. Microbiol. 59 (5) 429-514 [2012-09-00; online 2012-09-28]
Fabien Burki SciLifeLab Fellow
Stepping stones in DNA sequencing.
Stranneheim H, Lundeberg J
Biotechnol J 7 (9) 1063-1073 [2012-09-00; online 2012-08-08]
Affiliated researcher
Positive allosteric feedback regulation of the stringent response enzyme RelA by its product.
Shyp V, Tankov S, Ermakov A, ..., Elf J, Hauryliuk V
EMBO Rep. 13 (9) 835-839 [2012-09-00; online 2012-07-20]
Affiliated researcher
Nanoscopy of Living Brain Slices with Low Light Levels
Testa I, Urban NT, Jakobs S, ..., Willig KI, Hell SW
Neuron 75 (6) 992-1000 [2012-09-00; online 2012-09-00]
Ilaria Testa SciLifeLab Fellow
IQGAP1 regulates hyaluronan-mediated fibroblast motility and proliferation.
Kozlova I, Ruusala A, Voytyuk O, Skandalis SS, Heldin P
Cell. Signal. 24 (9) 1856-1862 [2012-09-00; online 2012-05-22]
Affiliated researcher
Molecular correlates and prognostic significance of SATB1 expression in colorectal cancer.
Nodin B, Johannesson H, Wangefjord S, ..., Jirström K, Eberhard J
Diagn Pathol 7 (-) 115 [2012-08-30; online 2012-08-30]
Affiliated researcher
Genome-wide polyadenylation site mapping.
Pelechano V, Wilkening S, Järvelin AI, Tekkedil MM, Steinmetz LM
Meth. Enzymol. 513 (-) 271-296 [2012-08-30; online 2012-08-30]
SciLifeLab Fellow Vicent Pelechano
Novel origins of copy number variation in the dog genome.
Berglund J, Nevalainen EM, Molin AM, ..., Lohi H, Webster MT
Genome Biol. 13 (8) R73 [2012-08-23; online 2012-08-23]
Affiliated researcher
Large-Scale Identification of MicroRNA Targets in Murine Dgcr8-Deficient Embryonic Stem Cell Lines
Davis MPA, Abreu-Goodger C, van Dongen S, ..., Enright AJ, Dunham I
PLoS ONE 7 (8) e41762 [2012-08-17; online 2012-08-17]
Claudia Kutter SciLifeLab Fellow
Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy.
Leandro-García LJ, Leskelä S, Jara C, ..., Robledo M, Rodríguez-Antona C
Clin. Cancer Res. 18 (16) 4441-4448 [2012-08-15; online 2012-06-20]
Affiliated researcher
Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.
Arabi A, Ullah K, Branca RM, ..., Lehtiö J, Sangfelt O
Nat Commun 3 (-) 976 [2012-08-07; online 2012-08-07]
Affiliated researcher
Platelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation.
Edqvist PH, Niklasson M, Vidal-Sanz M, Hallböök F, Forsberg-Nilsson K
PLoS ONE 7 (8) e42488 [2012-08-03; online 2012-08-03]
Affiliated researcher
Copy number expansion of the STX17 duplication in melanoma tissue from Grey horses.
Sundström E, Imsland F, Mikko S, ..., Lindblad-Toh K, Andersson L
BMC Genomics 13 (-) 365 [2012-08-02; online 2012-08-02]
Affiliated researcher
Long noncoding RNA-mediated maintenance of DNA methylation and transcriptional gene silencing.
Mohammad F, Pandey GK, Mondal T, ..., Gyllensten U, Kanduri C
Development 139 (15) 2792-2803 [2012-08-00; online 2012-06-21]
Affiliated researcher
Intractable epilepsy of infancy due to homozygous mutation in the EFHC1 gene.
Berger I, Dor T, Halvardson J, ..., Feuk L, Elpeleg O
Epilepsia 53 (8) 1436-1440 [2012-08-00; online 2012-06-12]
Affiliated researcher
From where did the Western honeybee (Apis mellifera) originate?
Han F, Wallberg A, Webster MT
Ecol Evol 2 (8) 1949-1957 [2012-08-00; online 2012-07-12]
Affiliated researcher
A-to-I editing of microRNAs in the mammalian brain increases during development.
Ekdahl Y, Farahani HS, Behm M, Lagergren J, Öhman M
Genome Res. 22 (8) 1477-1487 [2012-08-00; online 2012-05-29]
Affiliated researcher
A guideline to proteome-wide α-helical membrane protein topology predictions.
Tsirigos KD, Hennerdal A, Käll L, Elofsson A
Proteomics 12 (14) 2282-2294 [2012-08-00; online 2012-06-12]
Affiliated researcher
Antiparallel dimers of the small multidrug resistance protein EmrE are more stable than parallel dimers.
Lloris-Garcerá P, Bianchi F, Slusky JS, ..., Daley DO, von Heijne G
J. Biol. Chem. 287 (31) 26052-26059 [2012-07-27; online 2012-06-14]
Affiliated researcher
Rapid Turnover of Long Noncoding RNAs and the Evolution of Gene Expression
Kutter C, Watt S, Stefflova K, ..., Odom DT, Marques AC
PLoS Genet 8 (7) e1002841 [2012-07-26; online 2012-07-26]
Claudia Kutter SciLifeLab Fellow
Sensitive detection of spores using volume-amplified magnetic nanobeads.
Gómez de la Torre TZ, Ke R, Mezger A, ..., Strømme M, Nilsson M
Small 8 (14) 2174-2177 [2012-07-23; online 2012-04-19]
Affiliated researcher
Coexistence of phases in a protein heterodimer.
Krokhotin A, Liwo A, Niemi AJ, Scheraga HA
J Chem Phys 137 (3) 035101 [2012-07-21; online 2012-07-27]
Affiliated researcher
Evidence of inbreeding depression on human height.
McQuillan R, Eklund N, Pirastu N, ..., Wilson JF, ROHgen Consortium
PLoS Genet 8 (7) e1002655 [2012-07-19; online 2012-07-19]
Affiliated researcher
Profiling cellular protein complexes by proximity ligation with dual tag microarray readout.
Hammond M, Nong RY, Ericsson O, Pardali K, Landegren U
PLoS ONE 7 (7) e40405 [2012-07-10; online 2012-07-10]
Affiliated researcher
Regulation of EMT by TGFβ in cancer.
Heldin CH, Vanlandewijck M, Moustakas A
FEBS Lett. 586 (14) 1959-1970 [2012-07-04; online 2012-02-28]
Affiliated researcher
Next generation RNA-sequencing in prognostic subsets of chronic lymphocytic leukemia.
Mansouri L, Gunnarsson R, Sutton LA, ..., Gyllensten U, Rosenquist R
Am. J. Hematol. 87 (7) 737-740 [2012-07-00; online 2012-06-03]
Affiliated researcher
Microsatellite genotyping reveals end-Pleistocene decline in mammoth autosomal genetic variation.
Nyström V, Humphrey J, Skoglund P, ..., Lister A, Dalén L
Mol. Ecol. 21 (14) 3391-3402 [2012-07-00; online 2012-03-23]
Affiliated researcher
Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V.
Schmees C, Villaseñor R, Zheng W, ..., Heldin CH, Hellberg C
Mol. Biol. Cell 23 (13) 2571-2582 [2012-07-00; online 2012-05-09]
Affiliated researcher
The lac repressor displays facilitated diffusion in living cells.
Hammar P, Leroy P, Mahmutovic A, ..., Berg OG, Elf J
Science 336 (6088) 1595-1598 [2012-06-22; online 2012-06-23]
Affiliated researcher
Proteomic analysis of cerebrospinal fluid in a fulminant case of multiple sclerosis.
Füvesi J, Hanrieder J, Bencsik K, ..., Vécsei L, Bergquist J
Int J Mol Sci 13 (6) 7676-7693 [2012-06-21; online 2012-06-21]
Affiliated researcher
Visualising individual sequence-specific protein-DNA interactions in situ.
Weibrecht I, Gavrilovic M, Lindbom L, ..., Wählby C, Söderberg O
N Biotechnol 29 (5) 589-598 [2012-06-15; online 2011-08-31]
Affiliated researcher
Validation of affinity reagents using antigen microarrays.
Sjöberg R, Sundberg M, Gundberg A, ..., Uhlén M, Nilsson P
N Biotechnol 29 (5) 555-563 [2012-06-15; online 2011-11-23]
Affiliated researcher
Two loci on chromosome 5 are associated with serum IgE levels in Labrador retrievers.
Owczarek-Lipska M, Lauber B, Molitor V, ..., Marti E, Leeb T
PLoS ONE 7 (6) e39176 [2012-06-15; online 2012-06-15]
Affiliated researcher
Classification of protein profiles from antibody microarrays using heat and detergent treatment.
Häggmark A, Neiman M, Drobin K, ..., Nilsson P, Schwenk JM
N Biotechnol 29 (5) 564-570 [2012-06-15; online 2011-10-14]
Affiliated researcher
Rethinking dog domestication by integrating genetics, archeology, and biogeography.
Larson G, Karlsson EK, Perri A, ..., Andersson L, Lindblad-Toh K
Proc. Natl. Acad. Sci. U.S.A. 109 (23) 8878-8883 [2012-06-05; online 2012-05-21]
Affiliated researcher
Minor structural modifications to alchemix influence mechanism of action and pharmacological activity.
Abdallah QM, Phillips RM, Johansson F, ..., Patterson LH, Pors K
Biochem. Pharmacol. 83 (11) 1514-1522 [2012-06-01; online 2012-03-01]
Affiliated researcher
Collodictyon--An Ancient Lineage in the Tree of Eukaryotes
Zhao S, Burki F, Brate J, ..., Klaveness D, Shalchian-Tabrizi K
Molecular Biology and Evolution 29 (6) 1557-1568 [2012-06-01; online 2012-01-06]
Fabien Burki SciLifeLab Fellow
Which sequencing depth is sufficient to describe patterns in bacterial α- and β-diversity?
Lundin D, Severin I, Logue JB, ..., Andersson AF, Lindström ES
Environ Microbiol Rep 4 (3) 367-372 [2012-06-00; online 2012-04-23]
Affiliated researcher
Studies on the restriction of murine leukemia viruses by mouse APOBEC3.
Sanchez-Martinez S, Aloia AL, Harvin D, ..., Coffin JM, Rein A
PLoS ONE 7 (5) e38190 [2012-05-29; online 2012-05-29]
Affiliated researcher
De-novo transcriptome sequencing of a normalized cDNA pool from influenza infected ferrets.
Camp JV, Svensson TL, McBrayer A, ..., Liljeström P, Bruder CE
PLoS ONE 7 (5) e37104 [2012-05-11; online 2012-05-11]
Affiliated researcher
Lipid-based passivation in nanofluidics.
Persson F, Fritzsche J, Mir KU, ..., Westerlund F, Tegenfeldt JO
Nano Lett. 12 (5) 2260-2265 [2012-05-09; online 2012-04-06]
Affiliated researcher
Elucidating membrane structure and protein behavior using giant plasma membrane vesicles.
Sezgin E, Kaiser HJ, Baumgart T, ..., Simons K, Levental I
Nat Protoc 7 (6) 1042-1051 [2012-05-03; online 2012-05-03]
Erdinc Sezgin SciLifeLab Fellow
Thapsigargin down-regulates protein levels of GRP78/BiP in INS-1E cells.
Rosengren V, Johansson H, Lehtiö J, ..., Sjöholm A, Ortsäter H
J. Cell. Biochem. 113 (5) 1635-1644 [2012-05-00; online 2011-12-23]
Affiliated researcher
Primary high-risk HPV screening for cervical cancer in post-menopausal women.
Gyllensten U, Gustavsson I, Lindell M, Wilander E
Gynecol. Oncol. 125 (2) 343-345 [2012-05-00; online 2012-01-28]
Affiliated researcher
Origins of domestic dog in southern East Asia is supported by analysis of Y-chromosome DNA.
Ding ZL, Oskarsson M, Ardalan A, ..., Savolainen P, Zhang YP
Heredity (Edinb) 108 (5) 507-514 [2012-05-00; online 2011-11-23]
Affiliated researcher
Neural stem cells: brain building blocks and beyond.
Bergström T, Forsberg-Nilsson K
Ups. J. Med. Sci. 117 (2) 132-142 [2012-05-00; online 2012-04-20]
Affiliated researcher
Genetic architecture and adaptive significance of the selfing syndrome in Capsella.
Slotte T, Hazzouri KM, Stern D, Andolfatto P, Wright SI
Evolution 66 (5) 1360-1374 [2012-05-00; online 2012-03-03]
SciLifeLab Fellow Tanja Slotte
Dopamine, working memory, and training induced plasticity: implications for developmental research.
Söderqvist S, Bergman Nutley S, Peyrard-Janvid M, ..., Kere J, Klingberg T
Dev Psychol 48 (3) 836-843 [2012-05-00; online 2011-11-21]
Affiliated researcher
Origins and genetic legacy of Neolithic farmers and hunter-gatherers in Europe.
Skoglund P, Malmström H, Raghavan M, ..., Götherström A, Jakobsson M
Science 336 (6080) 466-469 [2012-04-27; online 2012-04-28]
Affiliated researcher
An image analysis toolbox for high-throughput C. elegans assays.
Wählby C, Kamentsky L, Liu ZH, ..., Ausubel FM, Carpenter AE
Nat. Methods 9 (7) 714-716 [2012-04-22; online 2012-04-22]
Affiliated researcher
The genomic basis of adaptive evolution in threespine sticklebacks.
Jones FC, Grabherr MG, Chan YF, ..., Lindblad-Toh K, Kingsley DM
Nature 484 (7392) 55-61 [2012-04-04; online 2012-04-04]
Affiliated researcher
Activated paper surfaces for the rapid hybridization of DNA through capillary transport.
Araújo AC, Song Y, Lundeberg J, Ståhl PL, Brumer H
Anal. Chem. 84 (7) 3311-3317 [2012-04-03; online 2012-03-12]
Affiliated researcher
Role of cis-12-Oxo-Phytodienoic Acid in Tomato Embryo Development
Goetz S, Hellwege A, Stenzel I, ..., Wasternack C, Hause B
PLANT PHYSIOLOGY 158 (4) 1715-1727 [2012-04-01; online 2012-02-14]
Claudia Kutter SciLifeLab Fellow
Proteomic profiling of follicular and papillary thyroid tumors.
Sofiadis A, Becker S, Hellman U, ..., Lehtiö J, Larsson C
Eur. J. Endocrinol. 166 (4) 657-667 [2012-04-00; online 2012-01-24]
Affiliated researcher
Mantle cell lymphoma displays a homogenous methylation profile: a comparative analysis with chronic lymphocytic leukemia.
Halldórsdóttir AM, Kanduri M, Marincevic M, ..., Ehrencrona H, Rosenquist R
Am. J. Hematol. 87 (4) 361-367 [2012-04-00; online 2012-02-28]
Affiliated researcher
Manipulating the genetic code for membrane protein production: what have we learnt so far?
Nørholm MH, Light S, Virkki MT, ..., von Heijne G, Daley DO
Biochim. Biophys. Acta 1818 (4) 1091-1096 [2012-04-00; online 2011-08-22]
Affiliated researcher
Chromatographic retention time prediction for posttranslationally modified peptides.
Moruz L, Staes A, Foster JM, ..., Martens L, Käll L
Proteomics 12 (8) 1151-1159 [2012-04-00; online 2012-05-12]
Affiliated researcher
Undersulfation of heparan sulfate restricts differentiation potential of mouse embryonic stem cells.
Forsberg M, Holmborn K, Kundu S, ..., Kjellén L, Forsberg-Nilsson K
J. Biol. Chem. 287 (14) 10853-10862 [2012-03-30; online 2012-02-01]
Affiliated researcher
Penetration of amphiphilic quantum dots through model and cellular plasma membranes.
Dubavik A, Sezgin E, Lesnyak V, ..., Schwille P, Eychmüller A
ACS Nano 6 (3) 2150-2156 [2012-03-27; online 2012-02-13]
Erdinc Sezgin SciLifeLab Fellow
Signaling pathways involved in the regulation of TNFα-induced toll-like receptor 2 expression in human gingival fibroblasts.
Davanian H, Båge T, Lindberg J, ..., Sällberg Chen M, Yucel-Lindberg T
Cytokine 57 (3) 406-416 [2012-03-00; online 2012-01-05]
Affiliated researcher
Narrow genetic basis for the Australian dingo confirmed through analysis of paternal ancestry.
Ardalan A, Oskarsson M, Natanaelsson C, ..., Ahmadian A, Savolainen P
Genetica 140 (1-3) 65-73 [2012-03-00; online 2012-05-23]
Affiliated researcher
Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.
Larance M, Kirkwood KJ, Xirodimas DP, ..., Uhlen M, Lamond AI
Mol. Cell Proteomics 11 (3) M111.014407 [2012-03-00; online 2011-10-29]
Affiliated researcher
Antibody-based protein profiling of the human chromosome 21.
Uhlén M, Oksvold P, Älgenäs C, ..., Kondo T, Sivertsson Å
Mol. Cell Proteomics 11 (3) M111.013458 [2012-03-00; online 2011-10-31]
Affiliated researcher
Advancing cell biology through proteomics in space and time (PROSPECTS).
Lamond AI, Uhlen M, Horning S, ..., Aebersold R, Mann M
Mol. Cell Proteomics 11 (3) O112.017731 [2012-03-00; online 2012-02-06]
Affiliated researcher
The dyslexia candidate gene DYX1C1 is a potential marker of poor survival in breast cancer.
Rosin G, Hannelius U, Lindström L, ..., Hartman J, Kere J
BMC Cancer 12 (-) 79 [2012-02-29; online 2012-02-29]
Affiliated researcher
Opportunities for sensitive plasma proteome analysis.
Landegren U, Vänelid J, Hammond M, ..., Ullerås E, Kamali-Moghaddam M
Anal. Chem. 84 (4) 1824-1830 [2012-02-21; online 2012-02-01]
Affiliated researcher
Gis1 and Rph1 regulate glycerol and acetate metabolism in glucose depleted yeast cells.
Orzechowski Westholm J, Tronnersjö S, Nordberg N, ..., Komorowski J, Ronne H
PLoS ONE 7 (2) e31577 [2012-02-21; online 2012-02-21]
Affiliated researcher
DNA-assisted protein detection technologies.
Nong RY, Gu J, Darmanis S, Kamali-Moghaddam M, Landegren U
Expert Rev Proteomics 9 (1) 21-32 [2012-02-02; online 2012-02-02]
Affiliated researcher
Select microRNAs are essential for early development in the sea urchin
Song JL, Stoeckius M, Maaskola J, ..., Rajewsky N, Wessel GM
Developmental Biology 362 (1) 104-113 [2012-02-00; online 2012-02-00]
Marc Friedländer SciLifeLab Fellow
Low diversity of the gut microbiota in infants with atopic eczema.
Abrahamsson TR, Jakobsson HE, Andersson AF, ..., Engstrand L, Jenmalm MC
J. Allergy Clin. Immunol. 129 (2) 434-40, 440.e1-2 [2012-02-00; online 2011-12-06]
Affiliated researcher
Human ROBO1 regulates interaural interaction in auditory pathways.
Lamminmäki S, Massinen S, Nopola-Hemmi J, Kere J, Hari R
J. Neurosci. 32 (3) 966-971 [2012-01-18; online 2012-01-21]
Affiliated researcher
Molecular recognition of a single sphingolipid species by a protein's transmembrane domain.
Contreras FX, Ernst AM, Haberkant P, ..., Wieland F, Brügger B
Nature 481 (7382) 525-529 [2012-01-09; online 2012-01-09]
Affiliated researcher
Combinations of histone modifications mark exon inclusion levels.
Enroth S, Bornelöv S, Wadelius C, Komorowski J
PLoS ONE 7 (1) e29911 [2012-01-05; online 2012-01-05]
Affiliated researcher
The Pfam protein families database.
Punta M, Coggill PC, Eberhardt RY, ..., Bateman A, Finn RD
Nucleic Acids Res. 40 (Database issue) D290-D301 [2012-01-00; online 2011-11-29]
Affiliated researcher
Role of Smads in TGFβ signaling.
Heldin CH, Moustakas A
Cell Tissue Res. 347 (1) 21-36 [2012-01-00; online 2011-06-04]
Affiliated researcher
Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome.
Axelsson E, Webster MT, Ratnakumar A, ..., Ponting CP, Lindblad-Toh K
Genome Res. 22 (1) 51-63 [2012-01-00; online 2011-10-17]
Affiliated researcher
Comparative interactomics with Funcoup 2.0.
Alexeyenko A, Schmitt T, Tjärnberg A, ..., Frings O, Sonnhammer EL
Nucleic Acids Res. 40 (Database issue) D821-D828 [2012-01-00; online 2011-11-21]
Affiliated researcher
Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins.
Sideridou M, Zakopoulou R, Evangelou K, ..., Moustakas A, Gorgoulis VG
J. Cell Biol. 195 (7) 1123-1140 [2011-12-26; online 2011-12-28]
Affiliated researcher
Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1).
Anedda F, Zucchelli M, Schepis D, ..., Kere J, D'Amato M
PLoS ONE 6 (12) e29523 [2011-12-21; online 2011-12-21]
Affiliated researcher
Assessing recent smoking status by measuring exhaled carbon monoxide levels.
Sandberg A, Sköld CM, Grunewald J, Eklund A, Wheelock ÅM
PLoS ONE 6 (12) e28864 [2011-12-16; online 2011-12-16]
Affiliated researcher
A disposable and multifunctional capsule for easy operation of microfluidic elastomer systems
Thorslund S, Nguyen H, Läräng T, Barkefors I, Kreuger J
J. Micromech. Microeng. 21 (12) 127001 [2011-12-01; online 2011-11-24]
Affiliated researcher
The Conserved Foot Domain of RNA Pol II Associates with Proteins Involved in Transcriptional Initiation and/or Early Elongation
García-López MC, Pelechano V, Mirón-García MC, ..., Pérez-Ortín JE, Navarro F
Genetics 189 (4) 1235-1248 [2011-12-00; online 2011-09-27]
SciLifeLab Fellow Vicent Pelechano
Postpartum depressive symptoms and the BDNF Val66Met functional polymorphism: effect of season of delivery.
Comasco E, Sylvén SM, Papadopoulos FC, ..., Sundström-Poromaa I, Skalkidou A
Arch Womens Ment Health 14 (6) 453-463 [2011-12-00; online 2011-10-14]
Erika Comasco SciLifeLab Fellow
High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer.
Hjelm B, Brennan DJ, Zendehrokh N, ..., Jirström K, Uhlen M
Proteomics Clin Appl 5 (11-12) 624-635 [2011-12-00; online 2011-10-01]
Affiliated researcher
Autoregulation of the nonsense-mediated mRNA decay pathway in human cells.
Yepiskoposyan H, Aeschimann F, Nilsson D, Okoniewski M, Mühlemann O
RNA 17 (12) 2108-2118 [2011-12-00; online 2011-10-25]
Affiliated researcher
Counting absolute numbers of molecules using unique molecular identifiers.
Kivioja T, Vähärautio A, Karlsson K, ..., Linnarsson S, Taipale J
Nat. Methods 9 (1) 72-74 [2011-11-20; online 2011-11-20]
Affiliated researcher
Genome sequencing reveals a phage in Helicobacter pylori.
Lehours P, Vale FF, Bjursell MK, ..., Engstrand L, Andersson AF
MBio 2 (6) - [2011-11-15; online 2011-11-15]
Affiliated researcher
A lateral flow protein microarray for rapid and sensitive antibody assays.
Gantelius J, Bass T, Sjöberg R, Nilsson P, Andersson-Svahn H
Int J Mol Sci 12 (11) 7748-7759 [2011-11-09; online 2011-11-09]
Affiliated researcher
Archaic human ancestry in East Asia.
Skoglund P, Jakobsson M
Proc. Natl. Acad. Sci. U.S.A. 108 (45) 18301-18306 [2011-11-08; online 2011-10-31]
Affiliated researcher
Plasma profiling reveals human fibulin-1 as candidate marker for renal impairment.
Neiman M, Hedberg JJ, Dönnes PR, ..., Schwenk JM, Nilsson P
J. Proteome Res. 10 (11) 4925-4934 [2011-11-04; online 2011-09-29]
Affiliated researcher
Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse.
Lindfors C, Nilsson IA, Garcia-Roves PM, ..., Schalling M, Johansen JE
Proc. Natl. Acad. Sci. U.S.A. 108 (44) 18108-18113 [2011-11-01; online 2011-10-24]
Affiliated researcher
Western blotting via proximity ligation for high performance protein analysis.
Liu Y, Gu J, Hagner-McWhirter Å, ..., Ivansson D, Landegren U
Mol. Cell Proteomics 10 (11) O111.011031 [2011-11-00; online 2011-08-02]
Affiliated researcher
The Human Protein Atlas as a proteomic resource for biomarker discovery.
Pontén F, Schwenk JM, Asplund A, Edqvist PH
J. Intern. Med. 270 (5) 428-446 [2011-11-00; online 2011-08-03]
Affiliated researcher
Oncolytic viruses for the treatment of neuroendocrine tumors.
Essand M, Leja J, Giandomenico V, Oberg KE
Horm. Metab. Res. 43 (12) 877-883 [2011-11-00; online 2011-05-30]
Affiliated researcher
Ligand discovery from a dopamine D3 receptor homology model and crystal structure
Carlsson J, Coleman RG, Setola V, ..., Roth BL, Shoichet BK
Nat Chem Biol 7 (11) 769-778 [2011-11-00; online 2011-09-18]
Jens Carlsson SciLifeLab Fellow
Generation of monospecific antibodies based on affinity capture of polyclonal antibodies.
Hjelm B, Forsström B, Igel U, ..., Johansson C, Uhlén M
Protein Sci. 20 (11) 1824-1835 [2011-11-00; online 2011-10-12]
Affiliated researcher
Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity.
Rasmussen M, Sundström M, Göransson Kultima H, ..., Glimelius B, Isaksson A
Genome Biol. 12 (10) R108 [2011-10-24; online 2011-10-24]
Affiliated researcher
Increased throughput of proteomics analysis by multiplexing high-resolution tandem mass spectra.
Ledvina AR, Savitski MM, Zubarev AR, ..., Coon JJ, Zubarev RA
Anal. Chem. 83 (20) 7651-7656 [2011-10-15; online 2011-09-28]
Affiliated researcher
MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas.
Mäkinen N, Mehine M, Tolvanen J, ..., Vahteristo P, Aaltonen LA
Science 334 (6053) 252-255 [2011-10-14; online 2011-08-25]
Affiliated researcher
A high-resolution map of human evolutionary constraint using 29 mammals.
Lindblad-Toh K, Garber M, Zuk O, ..., Lander ES, Kellis M
Nature 478 (7370) 476-482 [2011-10-12; online 2011-10-12]
Affiliated researcher
Transitions in bacterial communities along the 2000 km salinity gradient of the Baltic Sea.
Herlemann DP, Labrenz M, Jürgens K, ..., Waniek JJ, Andersson AF
ISME J 5 (10) 1571-1579 [2011-10-00; online 2011-04-07]
Affiliated researcher
Impact of CYP3A5*3 and CYP2C8-HapC on paclitaxel/carboplatin-induced myelosuppression in patients with ovarian cancer.
Gréen H, Khan MS, Jakobsen-Falk I, Åvall-Lundqvist E, Peterson C
J Pharm Sci 100 (10) 4205-4209 [2011-10-00; online 2011-06-23]
Affiliated researcher
Heme binding in gas-phase holo-myoglobin cations: distal becomes proximal?
Enyenihi AA, Yang H, Ytterberg AJ, Lyutvinskiy Y, Zubarev RA
J. Am. Soc. Mass Spectrom. 22 (10) 1763-1770 [2011-10-00; online 2011-07-19]
Affiliated researcher
Fibroblast growth factor 10 haploinsufficiency causes chronic obstructive pulmonary disease.
Klar J, Blomstrand P, Brunmark C, ..., Bergendal B, Dahl N
J. Med. Genet. 48 (10) 705-709 [2011-10-00; online 2011-07-08]
Affiliated researcher
Diffraction-unlimited all-optical imaging and writing with a photochromic GFP
Grotjohann T, Testa I, Leutenegger M, ..., Jakobs S, Hell SW
Nature 478 (7368) 204-208 [2011-10-00; online 2011-09-11]
Ilaria Testa SciLifeLab Fellow
ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing.
Darmanis S, Nong RY, Vänelid J, ..., Kamali-Moghaddam M, Landegren U
PLoS ONE 6 (9) e25583 [2011-09-29; online 2011-09-29]
Affiliated researcher
Genomic determinants of protein evolution and polymorphism in Arabidopsis.
Slotte T, Bataillon T, Hansen TT, ..., Wright SI, Schierup MH
Genome Biol Evol 3 (-) 1210-1219 [2011-09-16; online 2011-09-16]
SciLifeLab Fellow Tanja Slotte
Molecular Characteristics of ERCC1-Negative versus ERCC1-Positive Tumors in Resected NSCLC.
Friboulet L, Barrios-Gonzales D, Commo F, ..., André F, Soria JC
Clin. Cancer Res. 17 (17) 5562-5572 [2011-09-01; online 2011-07-12]
Affiliated researcher
Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation.
Hellström AR, Watt B, Fard SS, ..., Marks MS, Andersson L
PLoS Genet 7 (9) e1002285 [2011-09-00; online 2011-09-15]
Affiliated researcher
Deciphering the rules governing assembly order of mammalian septin complexes
Sellin ME, Sandblad L, Stenmark S, Gullberg M
MBoC 22 (17) 3152-3164 [2011-09-00; online 2011-09-00]
Mikael Sellin SciLifeLab Fellow
The genome of the green anole lizard and a comparative analysis with birds and mammals.
Alföldi J, Di Palma F, Grabherr M, ..., Ponting CP, Lindblad-Toh K
Nature 477 (7366) 587-591 [2011-08-31; online 2011-08-31]
Affiliated researcher
Short-time repeat high-risk HPV testing by self-sampling for screening of cervical cancer.
Gyllensten U, Sanner K, Gustavsson I, ..., Wikström I, Wilander E
Br. J. Cancer 105 (5) 694-697 [2011-08-23; online 2011-08-02]
Affiliated researcher
Overexpression of podocalyxin-like protein is an independent factor of poor prognosis in colorectal cancer.
Larsson A, Johansson ME, Wangefjord S, ..., Uhlén M, Jirström K
Br. J. Cancer 105 (5) 666-672 [2011-08-23; online 2011-08-09]
Affiliated researcher
Three periods of regulatory innovation during vertebrate evolution.
Lowe CB, Kellis M, Siepel A, ..., Lindblad-Toh K, Haussler D
Science 333 (6045) 1019-1024 [2011-08-19; online 2011-08-20]
Affiliated researcher
Titration-free 454 sequencing using Y adapters.
Zheng Z, Advani A, Melefors Ö, ..., Engstrand L, Andersson AF
Nat Protoc 6 (9) 1367-1376 [2011-08-18; online 2011-08-18]
Affiliated researcher
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
International Multiple Sclerosis Genetics Consortium , Wellcome Trust Case Control Consortium 2 , Sawcer S, ..., Donnelly P, Compston A
Nature 476 (7359) 214-219 [2011-08-10; online 2011-08-10]
Affiliated researcher
Mapping the subcellular protein distribution in three human cell lines.
Fagerberg L, Stadler C, Skogs M, ..., Uhlén M, Lundberg E
J. Proteome Res. 10 (8) 3766-3777 [2011-08-05; online 2011-06-29]
Affiliated researcher
Domain architecture conservation in orthologs.
Forslund K, Pekkari I, Sonnhammer EL
BMC Bioinformatics 12 (-) 326 [2011-08-05; online 2011-08-05]
Affiliated researcher
Influence of the COMT genotype on working memory and brain activity changes during development.
Dumontheil I, Roggeman C, Ziermans T, ..., Kere J, Klingberg T
Biol. Psychiatry 70 (3) 222-229 [2011-08-01; online 2011-04-22]
Affiliated researcher
The short non-coding transcriptome of the protozoan parasite Trypanosoma cruzi.
Franzén O, Arner E, Ferella M, ..., Andersson B, Daub CO
PLoS Negl Trop Dis 5 (8) e1283 [2011-08-00; online 2011-08-30]
Affiliated researcher
A screening method for phosphohistidine phosphatase 1 activity.
Beckman-Sundh U, Ek B, Zetterqvist O, Ek P
Ups. J. Med. Sci. 116 (3) 161-168 [2011-08-00; online 2011-06-17]
Affiliated researcher
A genomic view of mRNA turnover in yeast
Pérez-Ortín JE, Jordán-Pla A, Pelechano V
Comptes Rendus Biologies 334 (8-9) 647-654 [2011-08-00; online 2011-08-00]
SciLifeLab Fellow Vicent Pelechano
FAAST: Flow-space Assisted Alignment Search Tool.
Lysholm F, Andersson B, Persson B
BMC Bioinformatics 12 (-) 293 [2011-07-19; online 2011-07-19]
Affiliated researcher
Scalable transcriptome preparation for massive parallel sequencing.
Stranneheim H, Werne B, Sherwood E, Lundeberg J
PLoS ONE 6 (7) e21910 [2011-07-07; online 2011-07-07]
Affiliated researcher
Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.
Olerud J, Mokhtari D, Johansson M, ..., Welsh N, Carlsson PO
Diabetes 60 (7) 1946-1954 [2011-07-00; online 2011-05-26]
Gustaf Christoffersson SciLifeLab Fellow
Sequence scrambling in shotgun proteomics is negligible.
Goloborodko AA, Gorshkov MV, Good DM, Zubarev RA
J. Am. Soc. Mass Spectrom. 22 (7) 1121-1124 [2011-07-00; online 2011-04-15]
Affiliated researcher
LGI2 truncation causes a remitting focal epilepsy in dogs.
Seppälä EH, Jokinen TS, Fukata M, ..., Minassian BA, Lohi H
PLoS Genet 7 (7) e1002194 [2011-07-00; online 2011-07-28]
Affiliated researcher
Isolated oligodontia associated with mutations in EDARADD, AXIN2, MSX1, and PAX9 genes.
Bergendal B, Klar J, Stecksén-Blicks C, Norderyd J, Dahl N
Am. J. Med. Genet. A 155A (7) 1616-1622 [2011-07-00; online 2011-05-27]
Affiliated researcher
Functional consequences of bidirectional promoters
Wei W, Pelechano V, Järvelin AI, Steinmetz LM
Trends in Genetics 27 (7) 267-276 [2011-07-00; online 2011-07-00]
SciLifeLab Fellow Vicent Pelechano
CoMet--a web server for comparative functional profiling of metagenomes.
Lingner T, Asshauer KP, Schreiber F, Meinicke P
Nucleic Acids Res. 39 (Web Server issue) W518-W523 [2011-07-00; online 2011-05-26]
Affiliated researcher
Genome wide association study identifies KCNMA1 contributing to human obesity.
Jiao H, Arner P, Hoffstedt J, ..., Clement K, Dahlman I
BMC Med Genomics 4 (-) 51 [2011-06-28; online 2011-06-28]
Affiliated researcher
The asthma candidate gene NPSR1 mediates isoform specific downstream signalling.
Pietras CO, Vendelin J, Anedda F, ..., Söderhäll C, Kere J
BMC Pulm Med 11 (-) 39 [2011-06-27; online 2011-06-27]
Affiliated researcher
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
Kilpeläinen TO, Zillikens MC, Stančákova A, ..., Laakso M, Loos RJ
Nat. Genet. 43 (8) 753-760 [2011-06-26; online 2011-06-26]
Affiliated researcher
Mutations in Frizzled 6 cause isolated autosomal-recessive nail dysplasia.
Fröjmark AS, Schuster J, Sobol M, ..., Klar J, Dahl N
Am. J. Hum. Genet. 88 (6) 852-860 [2011-06-10; online 2011-06-15]
Affiliated researcher
Nanosilver on nanostructured silica: Antibacterial activity and Ag surface area.
Sotiriou GA, Teleki A, Camenzind A, ..., Panke S, Pratsinis SE
Chem Eng J 170 (2-3) 547-554 [2011-06-01; online 2011-06-01]
Alexandra Teleki SciLifeLab Fellow
Endolithic chlorophyll d-containing phototrophs.
Behrendt L, Larkum AW, Norman A, ..., Trampe E, Kühl M
ISME J 5 (6) 1072-1076 [2011-06-00; online 2010-12-16]
Lars Behrendt SciLifeLab Fellow
Association of the HLA-G gene +3142C>G polymorphism with systemic lupus erythematosus.
Consiglio CR, Veit TD, Monticielo OA, ..., Brenol JC, Chies JA
Tissue Antigens 77 (6) 540-545 [2011-06-00; online 2011-03-14]
Camila Consiglio DDLS Fellow
The zebrafish transcriptome during early development.
Vesterlund L, Jiao H, Unneberg P, Hovatta O, Kere J
BMC Dev. Biol. 11 (-) 30 [2011-05-24; online 2011-05-24]
Affiliated researcher
Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer.
Tavoosidana G, Ronquist G, Darmanis S, ..., Landegren UD, Kamali-Moghaddam M
Proc. Natl. Acad. Sci. U.S.A. 108 (21) 8809-8814 [2011-05-24; online 2011-05-09]
Affiliated researcher
Rapid screening of complex DNA samples by single-molecule amplification and sequencing.
Huang J, Zheng Z, Andersson AF, Engstrand L, Ye W
PLoS ONE 6 (5) e19723 [2011-05-19; online 2011-05-19]
Affiliated researcher
Full-length transcriptome assembly from RNA-Seq data without a reference genome.
Grabherr MG, Haas BJ, Yassour M, ..., Friedman N, Regev A
Nat. Biotechnol. 29 (7) 644-652 [2011-05-15; online 2011-05-15]
Affiliated researcher
Nitrogenase gene amplicons from global marine surface waters are dominated by genes of non-cyanobacteria.
Farnelid H, Andersson AF, Bertilsson S, ..., Hagström Å, Riemann L
PLoS ONE 6 (4) e19223 [2011-04-29; online 2011-04-29]
Affiliated researcher
Large scale library generation for high throughput sequencing.
Borgström E, Lundin S, Lundeberg J
PLoS ONE 6 (4) e19119 [2011-04-27; online 2011-04-27]
Affiliated researcher
Hybrid, silica-coated, Janus-like plasmonic-magnetic nanoparticles.
Sotiriou GA, Hirt AM, Lozach PY, ..., Krumeich F, Pratsinis SE
Chem Mater 23 (7) 1985-1992 [2011-04-12; online 2011-04-12]
Alexandra Teleki SciLifeLab Fellow
Systematic analysis of native membrane protein complexes in Escherichia coli.
Maddalo G, Stenberg-Bruzell F, Götzke H, ..., Ilag LL, Daley DO
J. Proteome Res. 10 (4) 1848-1859 [2011-04-01; online 2011-02-18]
Affiliated researcher
TIM23-mediated insertion of transmembrane α-helices into the mitochondrial inner membrane.
Botelho SC, Osterberg M, Reichert AS, ..., von Heijne G, Kim H
EMBO J. 30 (6) 1003-1011 [2011-03-16; online 2011-02-15]
Affiliated researcher
Decoding a substantial set of samples in parallel by massive sequencing.
Neiman M, Lundin S, Savolainen P, Ahmadian A
PLoS ONE 6 (3) e17785 [2011-03-09; online 2011-03-09]
Affiliated researcher
Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
Ameur A, Stewart JB, Freyer C, ..., Larsson NG, Gyllensten U
PLoS Genet 7 (3) e1002028 [2011-03-00; online 2011-03-24]
Affiliated researcher
Systematic antibody and antigen-based proteomic profiling with microarrays.
Ayoglu B, Häggmark A, Neiman M, ..., Schwenk JM, Nilsson P
Expert Rev. Mol. Diagn. 11 (2) 219-234 [2011-03-00; online 2011-03-17]
Affiliated researcher
CUBN is a gene locus for albuminuria.
Böger CA, Chen MH, Tin A, ..., Fox CS, Kao WH
J. Am. Soc. Nephrol. 22 (3) 555-570 [2011-03-00; online 2011-03-01]
Affiliated researcher
TGFbeta activates mitogen- and stress-activated protein kinase-1 (MSK1) to attenuate cell death.
van der Heide LP, van Dinther M, Moustakas A, ten Dijke P
J. Biol. Chem. 286 (7) 5003-5011 [2011-02-18; online 2010-11-24]
Affiliated researcher
Improved predictions by Pcons.net using multiple templates.
Larsson P, Skwark MJ, Wallner B, Elofsson A
Bioinformatics 27 (3) 426-427 [2011-02-01; online 2010-12-11]
Affiliated researcher
miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors.
Moskwa P, Buffa FM, Pan Y, ..., Helleday T, Chowdhury D
Mol. Cell 41 (2) 210-220 [2011-01-21; online 2010-12-30]
Affiliated researcher
Contributions of the EMERALD project to assessing and improving microarray data quality.
Beisvåg V, Kauffmann A, Malone J, ..., Sandvik AK, Kuiper M
BioTechniques 50 (1) 27-31 [2011-01-00; online 2011-01-15]
Affiliated researcher
Non-toxic dry-coated nanosilver for plasmonic biosensors.
Sotiriou GA, Sannomiya T, Teleki A, ..., Vörös J, Pratsinis SE
Adv. Funct. Mater. 20 (24) 4250-4257 [2010-12-21; online 2010-12-21]
Alexandra Teleki SciLifeLab Fellow
Defining the transcriptome and proteome in three functionally different human cell lines.
Lundberg E, Fagerberg L, Klevebring D, ..., Mann M, Uhlen M
Mol Syst Biol 6 (-) 450 [2010-12-21; online 2010-12-24]
Affiliated researcher
Analysis of transcript and protein overlap in a human osteosarcoma cell line.
Klevebring D, Fagerberg L, Lundberg E, ..., Uhlén M, Lundeberg J
BMC Genomics 11 (-) 684 [2010-12-02; online 2010-12-02]
Affiliated researcher
RNAs actively cycle on the Sm-like protein Hfq.
Fender A, Elf J, Hampel K, Zimmermann B, Wagner EG
Genes Dev. 24 (23) 2621-2626 [2010-12-01; online 2010-12-03]
Affiliated researcher
A Complete Set of Nascent Transcription Rates for Yeast Genes
Pelechano V, Chávez S, Pérez-Ortín JE
PLoS ONE 5 (11) e15442 [2010-11-16; online 2010-11-16]
SciLifeLab Fellow Vicent Pelechano
A Novel Synthetic Route for the Anti-HIV Drug MC-1220 and its Analogues
Loksha YM, Globisch D, Loddo R, ..., La Colla P, Pedersen EB
ChemMedChem 5 (11) 1847-1849 [2010-11-08; online 2010-08-16]
Daniel Globisch SciLifeLab Fellow
Heat shock transcription factor 1 localizes to sex chromatin during meiotic repression.
Akerfelt M, Vihervaara A, Laiho A, ..., Sistonen L, Henriksson E
J Biol Chem 285 (45) 34469-34476 [2010-11-05; online 2010-08-27]
Anniina Vihervaara SciLifeLab Fellow
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium 2 , Strange A, Capon F, ..., Donnelly P, Trembath RC
Nat. Genet. 42 (11) 985-990 [2010-11-00; online 2010-10-17]
Affiliated researcher
Far-Field Autofluorescence Nanoscopy
Bierwagen J, Testa I, Fölling J, ..., Eggeling C, Hell SW
Nano Lett. 10 (10) 4249-4252 [2010-10-13; online 2010-10-13]
Ilaria Testa SciLifeLab Fellow
Genome analysis and comparative genomics of a Giardia intestinalis assemblage E isolate.
Jerlström-Hultqvist J, Franzén O, Ankarklev J, ..., Svärd SG, Andersson B
BMC Genomics 11 (-) 543 [2010-10-07; online 2010-10-07]
Affiliated researcher
6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance.
Issaeva N, Thomas HD, Djureinovic T, ..., Curtin NJ, Helleday T
Cancer Res. 70 (15) 6268-6276 [2010-08-01; online 2010-07-14]
Affiliated researcher
Replication-biased genome organisation in the crenarchaeon Sulfolobus.
Andersson AF, Pelve EA, Lindeberg S, ..., Nilsson P, Bernander R
BMC Genomics 11 (-) 454 [2010-07-28; online 2010-07-28]
Affiliated researcher
Dynamics of HIV-1 quasispecies during antiviral treatment dissected using ultra-deep pyrosequencing.
Hedskog C, Mild M, Jernberg J, ..., Andersson B, Albert J
PLoS ONE 5 (7) e11345 [2010-07-07; online 2010-07-07]
Affiliated researcher
Classification of DNA sequences using Bloom filters.
Stranneheim H, Käller M, Allander T, ..., Arvestad L, Lundeberg J
Bioinformatics 26 (13) 1595-1600 [2010-07-01; online 2010-05-13]
Affiliated researcher
Control of membrane protein topology by a single C-terminal residue.
Seppälä S, Slusky JS, Lloris-Garcerá P, Rapp M, von Heijne G
Science 328 (5986) 1698-1700 [2010-06-25; online 2010-05-27]
Affiliated researcher
Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding
Schmidt D, Wilson MD, Ballester B, ..., Flicek P, Odom DT
Science 328 (5981) 1036-1040 [2010-05-21; online 2010-04-08]
Claudia Kutter SciLifeLab Fellow
Structure-Based Discovery of A2A Adenosine Receptor Ligands
Carlsson J, Yoo L, Gao ZG, ..., Shoichet BK, Jacobson KA
J. Med. Chem. 53 (9) 3748-3755 [2010-05-13; online 2010-05-13]
Jens Carlsson SciLifeLab Fellow
International network of cancer genome projects.
International Cancer Genome Consortium , Hudson TJ, Anderson W, ..., Liu ET, Wainwright BJ
Nature 464 (7291) 993-998 [2010-04-15; online 2010-04-16]
Affiliated researcher
In vivo and in vitro characterization of [18F]-FE-(+)-DTBZ as a tracer for beta-cell mass.
Eriksson O, Jahan M, Johnström P, ..., Halldin C, Johansson L
Nucl. Med. Biol. 37 (3) 357-363 [2010-04-00; online 2010-01-15]
Olof Eriksson SciLifeLab Fellow
Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions
Goldberg AD, Banaszynski LA, Noh KM, ..., Zheng D, Allis CD
Cell 140 (5) 678-691 [2010-03-00; online 2010-03-00]
SciLifeLab Fellow Simon Elsässer
Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination
Bienko M, Green CM, Sabbioneda S, ..., Lehmann AR, Dikic I
Molecular Cell 37 (3) 396-407 [2010-02-00; online 2010-02-00]
Magda Bienko SciLifeLab Fellow
Structure Determination and Improved Model of Plant Photosystem I
Amunts A, Toporik H, Borovikova A, Nelson N
J. Biol. Chem. 285 (5) 3478-3486 [2010-01-29; online 2009-11-18]
Alexey Amunts SciLifeLab Fellow
Deciphering the porcine intestinal microRNA transcriptome
Sharbati S, Friedlander MR, Sharbati J, ..., Rajewsky N, Einspanier R
BMC Genomics 11 (1) 275 [2010-00-00; online 2010-00-00]
Marc Friedländer SciLifeLab Fellow
Transcription factor AP2 beta involved in severe female alcoholism.
Nordquist N, Göktürk C, Comasco E, ..., Oreland L, Hallman J
Brain Res 1305 Suppl (-) S20-S26 [2009-12-11; online 2009-09-22]
Erika Comasco SciLifeLab Fellow
Large-scale sorting of C. elegans embryos reveals the dynamics of small RNA expression.
Stoeckius M, Maaskola J, Colombo T, ..., Piano F, Rajewsky N
Nat. Methods 6 (10) 745-751 [2009-10-00; online 2009-09-06]
Marc Friedländer SciLifeLab Fellow
Regulon-specific control of transcription elongation across the yeast genome.
Pelechano V, Jimeno-González S, Rodríguez-Gil A, ..., Pérez-Ortín JE, Chávez S
PLoS Genet 5 (8) e1000614 [2009-08-00; online 2009-08-21]
SciLifeLab Fellow Vicent Pelechano
High-resolution profiling and discovery of planarian small RNAs.
Friedländer MR, Adamidi C, Han T, ..., Kim JK, Rajewsky N
Proc. Natl. Acad. Sci. U.S.A. 106 (28) 11546-11551 [2009-07-14; online 2009-06-29]
Marc Friedländer SciLifeLab Fellow
Hermetically Coated Superparamagnetic Fe2O3Particles with SiO2Nanofilms
Teleki A, Suter M, Kidambi PR, ..., Nelson BJ, Pratsinis SE
Chem Mater 21 (10) 2094-2100 [2009-05-26; online 2009-05-26]
Alexandra Teleki SciLifeLab Fellow
The structure, regulation, and function of ZAP-70.
Au-Yeung BB, Deindl S, Hsu LY, ..., Kuriyan J, Weiss A
Immunol. Rev. 228 (1) 41-57 [2009-03-00; online 2009-03-18]
SciLifeLab Fellow Sebastian Deindl
Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization.
Sabbioneda S, Green CM, Bienko M, ..., Dikic I, Lehmann AR
Proc. Natl. Acad. Sci. U.S.A. 106 (8) E20; author reply E21 [2009-02-24; online 2009-02-26]
Magda Bienko SciLifeLab Fellow
Role of Gas−Aerosol Mixing during in Situ Coating of Flame-Made Titania Particles
Teleki A, Buesser B, Heine MC, ..., Akhtar MK, Pratsinis SE
Ind. Eng. Chem. Res. 48 (1) 85-92 [2009-01-07; online 2009-01-07]
Alexandra Teleki SciLifeLab Fellow
Picosecond fluorescence of intact and dissolved PSI-LHCI crystals.
van Oort B, Amunts A, Borst JW, ..., van Amerongen H, Croce R
Biophys. J. 95 (12) 5851-5861 [2008-12-15; online 2008-10-17]
Alexey Amunts SciLifeLab Fellow
Nanoscale separation of molecular species based on their rotational mobility.
Testa I, Schönle A, von Middendorff C, ..., Hell SW, Egner A
Opt Express 16 (25) 21093-21104 [2008-12-08; online 2008-12-10]
Ilaria Testa SciLifeLab Fellow
A human snoRNA with microRNA-like functions.
Ender C, Krek A, Friedländer MR, ..., Rajewsky N, Meister G
Mol. Cell 32 (4) 519-528 [2008-11-21; online 2008-11-26]
Marc Friedländer SciLifeLab Fellow
In situ coating of flame-made TiO2 particles with nanothin SiO2 films.
Teleki A, Heine MC, Krumeich F, Akhtar MK, Pratsinis SE
Langmuir 24 (21) 12553-12558 [2008-11-04; online 2008-10-11]
Alexandra Teleki SciLifeLab Fellow
Sortase-mediated assembly and surface topology of adhesive pneumococcal pili.
Fälker S, Nelson AL, Morfeldt E, ..., Normark S, Henriques-Normark B
Mol. Microbiol. 70 (3) 595-607 [2008-11-00; online 2008-09-17]
Kristina Jonas SciLifeLab Fellow
Importance of Bak for celecoxib-induced apoptosis.
Müller AC, Handrick R, Elsaesser SJ, ..., Belka C, Jendrossek V
Biochem. Pharmacol. 76 (9) 1082-1096 [2008-10-30; online 2008-08-19]
SciLifeLab Fellow Simon Elsässer
Photoactivation of pa-GFP in 3D: optical tools for spatial confinement.
Testa I, Garrè M, Parazzoli D, ..., Faretta M, Diaspro A
Eur Biophys J 37 (7) 1219-1227 [2008-09-00; online 2008-04-01]
Ilaria Testa SciLifeLab Fellow
Non-Linear Microscopy
Mazza D, Bianchini P, Caorsi V, ..., Vicidomini G, Diaspro A
Springer [book chapter] (-) 47-69 [2008-08-13]
Ilaria Testa SciLifeLab Fellow
Ferroelectric WO3Nanoparticles for Acetone Selective Detection
Wang L, Teleki A, Pratsinis SE, Gouma PI
Chem Mater 20 (15) 4794-4796 [2008-08-00; online 2008-08-00]
Alexandra Teleki SciLifeLab Fellow
Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration.
Palamidessi A, Frittoli E, Garré M, ..., Scita G, Di Fiore PP
Cell 134 (1) 135-147 [2008-07-11; online 2008-07-11]
Ilaria Testa SciLifeLab Fellow
Predicting binding modes from free energy calculations.
Nervall M, Hanspers P, Carlsson J, Boukharta L, Aqvist J
J. Med. Chem. 51 (9) 2657-2667 [2008-05-08; online 2008-04-12]
Jens Carlsson SciLifeLab Fellow
Modeling membranes under a transmembrane potential.
Delemotte L, Dehez F, Treptow W, Tarek M
J. Phys. Chem. B 112 (18) 5547-5550 [2008-05-08; online 2008-04-16]
Lucie Delemotte SciLifeLab Fellow
Spatial control of pa-GFP photoactivation in living cells.
Testa I, Parazzoli D, Barozzi S, ..., Faretta M, Diaspro A
J Microsc 230 (Pt 1) 48-60 [2008-04-00; online 2008-04-05]
Ilaria Testa SciLifeLab Fellow
Discovering microRNAs from deep sequencing data using miRDeep.
Friedländer MR, Chen W, Adamidi C, ..., Knespel S, Rajewsky N
Nat. Biotechnol. 26 (4) 407-415 [2008-04-00; online 2008-04-09]
Marc Friedländer SciLifeLab Fellow
Nanostructure Evolution: From Aggregated to Spherical SiO2 Particles Made in Diffusion Flames
Camenzind A, Schulz H, Teleki A, ..., Narayanan T, Pratsinis SE
Eur. J. Inorg. Chem. 2008 (6) 911-918 [2008-02-00; online 2008-02-00]
Alexandra Teleki SciLifeLab Fellow
Phylogenomics reshuffles the eukaryotic supergroups.
Burki F, Shalchian-Tabrizi K, Minge M, ..., Jakobsen KS, Pawlowski J
PLoS ONE 2 (8) e790 [2007-08-29; online 2007-08-29]
Fabien Burki SciLifeLab Fellow
MicroRNA-mediated regulation of stomatal development in Arabidopsis.
Kutter C, Schöb H, Stadler M, Meins F, Si-Ammour A
Plant Cell 19 (8) 2417-2429 [2007-08-00; online 2007-08-17]
Claudia Kutter SciLifeLab Fellow
Visualization of early engraftment in clinical islet transplantation by positron-emission tomography.
Eich T, Eriksson O, Lundgren T, Nordic Network for Clinical Islet Transplantation
N. Engl. J. Med. 356 (26) 2754-2755 [2007-06-28; online 2007-06-29]
Olof Eriksson SciLifeLab Fellow
Structural basis for the inhibition of tyrosine kinase activity of ZAP-70.
Deindl S, Kadlecek TA, Brdicka T, ..., Weiss A, Kuriyan J
Cell 129 (4) 735-746 [2007-05-18; online 2007-05-22]
SciLifeLab Fellow Sebastian Deindl
pH-dependent activation of the BarA-UvrY two-component system in Escherichia coli.
Mondragón V, Franco B, Jonas K, ..., Melefors O, Georgellis D
J. Bacteriol. 188 (23) 8303-8306 [2006-12-00; online 2006-09-15]
Kristina Jonas SciLifeLab Fellow
Sensing of organic vapors by flame-made TiO2 nanoparticles
Teleki A, Pratsinis SE, Kalyanasundaram K, Gouma PI
Sensors and Actuators B: Chemical 119 (2) 683-690 [2006-12-00; online 2006-12-00]
Alexandra Teleki SciLifeLab Fellow
Analysis of expressed sequence tags from a naked foraminiferan Reticulomyxa filosa.
Burki F, Nikolaev SI, Bolivar I, Guiard J, Pawlowski J
Genome 49 (8) 882-887 [2006-08-00; online 2006-10-13]
Fabien Burki SciLifeLab Fellow
A genomic study of the inter-ORF distances in Saccharomyces cerevisiae.
Pelechano V, García-Martínez J, Pérez-Ortín JE
Yeast 23 (9) 689-699 [2006-07-15; online 2006-07-18]
SciLifeLab Fellow Vicent Pelechano
Continuum solvation models in the linear interaction energy method.
Carlsson J, Andér M, Nervall M, Aqvist J
J. Phys. Chem. B 110 (24) 12034-12041 [2006-06-22; online 2006-06-28]
Jens Carlsson SciLifeLab Fellow
High-pressure liquid dispersion and fragmentation of flame-made silica agglomerates.
Wengeler R, Teleki A, Vetter M, Pratsinis SE, Nirschl H
Langmuir 22 (11) 4928-4935 [2006-05-23; online 2006-05-17]
Alexandra Teleki SciLifeLab Fellow
T2P-GFP: two-photon photoactivation of PA-GFP in the 720-840 nm spectral region.
Testa I, Schneider M, Barozzi S, ..., Faretta M, Diaspro A
- - (-) - [2006-02-09; online 2006-02-09]
Ilaria Testa SciLifeLab Fellow
The wound response in tomato--role of jasmonic acid.
Wasternack C, Stenzel I, Hause B, ..., Feussner I, Miersch O
J. Plant Physiol. 163 (3) 297-306 [2006-02-00; online 2005-12-20]
Claudia Kutter SciLifeLab Fellow
Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis.
Bienko M, Green CM, Crosetto N, ..., Hofmann K, Dikic I
Science (New York, N.Y.) 310 (5755) 1821-1824 [2005-12-16; online 2005-12-17]
Magda Bienko SciLifeLab Fellow
Flame-coating of titania particles with silica
Teleki A, Pratsinis SE, Wegner K, Jossen R, Krumeich F
J. Mater. Res. 20 (5) 1336-1347 [2005-05-00; online 2011-03-03]
Alexandra Teleki SciLifeLab Fellow
Enzymes of jasmonate biosynthesis occur in tomato sieve elements.
Hause B, Hause G, Kutter C, Miersch O, Wasternack C
Plant Cell Physiol. 44 (6) 643-648 [2003-06-00; online 2003-06-27]
Claudia Kutter SciLifeLab Fellow

Publications 9.5.0