Publications

Miller PG, Qiao D, Rojas-Quintero J, ..., Ebert BL, COPDGene Study Investigators, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine Consortium

Blood 139 (3) 357-368 [2022-01-20; online 2021-12-03]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

An Image-Analysis-Based Method for the Prediction of Recombinant Protein Fiber Tensile Strength.

Bäcklund FG, Schmuck B, Miranda GHB, ..., Rydén J, Rising A

Materials (Basel) 15 (3) - [2022-01-18; online 2022-01-18]

Gisele Miranda SciLifeLab Fellow

PubMed DOI Crossref

CCT3-LINC00326 axis regulates hepatocarcinogenic lipid metabolism.

Søndergaard JN, Sommerauer C, Atanasoai I, ..., Barragan I, Kutter C

Gut 71 (10) 2081-2092 [2022-01-12; online 2022-01-12]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Functional dissection of inherited non-coding variation influencing multiple myeloma risk.

Ajore R, Niroula A, Pertesi M, ..., Houlston R, Nilsson B

Nat Commun 13 (1) 151 [2022-01-10; online 2022-01-10]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo.

Hanke L, Das H, Sheward DJ, ..., Murrell B, McInerney GM

Nat Commun 13 (1) 155 [2022-01-10; online 2022-01-10]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

MirGeneDB 2.1: toward a complete sampling of all major animal phyla.

Fromm B, Høye E, Domanska D, ..., Friedländer MR, Peterson KJ

Nucleic Acids Res. 50 (D1) D204-D210 [2022-01-07; online 2021-12-02]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

TRP channels: branching out into the fungal kingdom.

Hellmich UA, Delemotte L

Structure 30 (1) 2-4 [2022-01-06; online 2022-01-08]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

A Genomic Perspective Across Earth's Microbiomes Reveals That Genome Size in Archaea and Bacteria Is Linked to Ecosystem Type and Trophic Strategy.

Rodríguez-Gijón A, Nuy JK, Mehrshad M, ..., Woyke T, Garcia SL

Front Microbiol 12 (-) 761869 [2022-01-05; online 2022-01-05]

Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist.

Bossart M, Wagner M, Elvert R, ..., Nitsche A, Konkar A

Cell Metab. 34 (1) 59-74.e10 [2022-01-04; online 2021-12-20]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

An open state of a voltage-gated sodium channel involving a π-helix and conserved pore-facing asparagine.

Choudhury K, Kasimova MA, McComas S, Howard RJ, Delemotte L

Biophys. J. 121 (1) 11-22 [2022-01-04; online 2021-12-08]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Spatial analysis of histology in 3D: quantification and visualization of organ and tumor level tissue environment.

Ruusuvuori P, Valkonen M, Kartasalo K, ..., Nykter M, Latonen L

Heliyon 8 (1) e08762 [2022-01-00; online 2022-01-14]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Revisiting sORFs: overcoming challenges to identify and characterize functional microproteins.

Schlesinger D, Elsässer SJ

FEBS J. 289 (1) 53-74 [2022-01-00; online 2021-02-24]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Putative regulation of macrophage-mediated inflammation by catestatin.

Muntjewerff EM, Christoffersson G, Mahata SK, van den Bogaart G

Trends Immunol. 43 (1) 41-50 [2022-01-00; online 2021-11-27]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Improvement of the performance of anticancer peptides using a drug repositioning pipeline.

Mohammadi E, Tahmoorespur M, Benfeitas R, ..., Mardinoglu A, Sekhavati MH

Biotechnol J 17 (1) e2100417 [2022-01-00; online 2021-11-14]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Identification of dynamic mass-action biochemical reaction networks using sparse Bayesian methods.

Jiang R, Singh P, Wrede F, Hellander A, Petzold L

PLoS Comput Biol 18 (1) e1009830 [2022-01-00; online 2022-01-31]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Distinct transcription kinetics of pluripotent cell states.

Shao R, Kumar B, Lidschreiber K, ..., Cramer P, Elsässer SJ

Mol Syst Biol 18 (1) e10407 [2022-01-00; online 2022-01-13]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Cell type-specific analysis by single-cell profiling identifies a stable mammalian tRNA-mRNA interface and increased translation efficiency in neurons.

Gao W, Gallardo-Dodd CJ, Kutter C

Genome Res 32 (1) 97-110 [2022-01-00; online 2021-12-02]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Artificial intelligence for diagnosis and Gleason grading of prostate cancer: the PANDA challenge.

Bulten W, Kartasalo K, Chen PC, ..., Eklund M, PANDA challenge consortium

Nat. Med. 28 (1) 154-163 [2022-01-00; online 2022-01-13]

DDLS Fellow Kimmo Kartasalo

DOI Crossref

Enhanced Sampling Methods for Molecular Dynamics Simulations [Article v1.0]

Hénin J, Lelièvre T, Shirts MR, Valsson O, Delemotte L

LiveCoMS 4 (1) - [2022-00-00; online 2022-00-00]

Lucie Delemotte SciLifeLab Fellow

DOI Crossref

Cholesterol stiffening of lipid membranes and drug interactions: Insights from neutron spin echo and deuterium NMR spectroscopy

Gupta S, Doole FT, Kumarage T, ..., Ashkar R, Brown MF

- - (-) 771-796 [2022-00-00; online 2022-00-00]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Therapeutic Potential of Ferulic Acid in Alzheimer's Disease.

Turkez H, Arslan ME, Barboza JN, ..., de Sousa DP, Mardinoğlu A

Curr Drug Deliv 19 (8) 860-873 [2021-12-30; online 2021-12-30]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Potential of [11C]UCB-J as a PET tracer for islets of Langerhans.

Puuvuori E, Rokka J, Carlsson PO, ..., Eriksson J, Eriksson O

Sci Rep 11 (1) 24466 [2021-12-28; online 2021-12-28]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Regional Brain Analysis of Modified Amino Acids and Dipeptides during the Sleep/Wake Cycle.

Vallianatou T, Bèchet NB, Correia MSP, Lundgaard I, Globisch D

Metabolites 12 (1) - [2021-12-27; online 2021-12-27]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Accurate spliced alignment of long RNA sequencing reads

Sahlin K, Mäkinen V

Bioinformatics 37 (24) 4643-4651 [2021-12-11; online 2021-07-24]

Kristoffer Sahlin SciLifeLab Fellow

PubMed DOI Crossref

Systems Biology Approaches to Decipher the Underlying Molecular Mechanisms of Glioblastoma Multiforme.

Kaynar A, Altay O, Li X, ..., Shoaie S, Mardinoglu A

Int J Mol Sci 22 (24) 13213 [2021-12-08; online 2021-12-08]

Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes.

Carravilla P, Dasgupta A, Zhurgenbayeva G, ..., Sezgin E, Eggeling C

Biophys Rep (N Y) 1 (2) None [2021-12-08; online 2021-12-08]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Genomic Signatures of Sexual Selection on Pollen-Expressed Genes in Arabis alpina.

Gutiérrez-Valencia J, Fracassetti M, Horvath R, ..., Kolář F, Slotte T

Mol. Biol. Evol. - (-) - [2021-12-08; online 2021-12-08] Open Access

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

What Is the Role of the Environment in the Emergence of Novel Antibiotic Resistance Genes? A Modeling Approach.

Bengtsson-Palme J, Jonsson V, Heß S

Environ. Sci. Technol. 55 (23) 15734-15743 [2021-12-07; online 2021-11-18]

DDLS Fellow Johan Bengtsson-Palme

DOI Crossref

Proactive autoscaling for edge computing systems with kubernetes

Ju L, Singh P, Toor S

- - (-) - [2021-12-06; online 2022-02-07]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis.

Kim PG, Niroula A, Shkolnik V, ..., Natarajan P, Ebert BL

J. Exp. Med. 218 (12) - [2021-12-06; online 2021-10-26]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

The Current State of Beta-Cell-Mass PET Imaging for Diabetes Research and Therapies.

Cheung P, Eriksson O

Biomedicines 9 (12) - [2021-12-03; online 2021-12-03]

Olof Eriksson SciLifeLab Fellow

DOI Crossref

Smart3-ATAC: a highly sensitive method for joint accessibility and full-length transcriptome analysis in single cells

Cheng H, Pui Hp, Lentini A, ..., Deng Q, Enge M

- - (-) - [2021-12-03; online 2021-12-03]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire.

Fattinger SA, Sellin ME, Hardt WD

Curr Opin Microbiol 64 (-) 9-18 [2021-12-00; online 2021-09-06]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Next generation plasma proteome profiling of COVID-19 patients with mild to moderate symptoms.

Zhong W, Altay O, Arif M, ..., Uhlen M, Fagerberg L

EBioMedicine 74 (-) 103723 [2021-12-00; online 2021-11-27]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

In vitro transcriptome response to propolis in differentiated SH-SY5Y neurons.

Turkez H, Arslan ME, Yilmaz A, ..., Abd El-Aty AM, Mardinoglu A

J Food Biochem 45 (12) e13990 [2021-12-00; online 2021-11-03]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

A bioinformatic platform to integrate target capture and whole genome sequences of various read depths for phylogenomics.

G Ribeiro P, Torres Jiménez MF, Andermann T, ..., Bacon CD, Matos-Maraví P

Mol. Ecol. 30 (23) 6021-6035 [2021-12-00; online 2021-10-31]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

Safety in multi-assembly via paths appearing in all path covers of a DAG.

Caceres M, Mumey B, Husic E, ..., Sahlin K, Tomescu AII

IEEE/ACM Trans Comput Biol Bioinform PP (-) - [2021-11-30; online 2021-11-30]

Kristoffer Sahlin SciLifeLab Fellow

DOI Crossref

Genomic and niche divergence in an Amazonian palm species complex

Bacon CD, Roncal J, Andermann T, ..., Tunarosa N, Antonelli A

- 197 (4) 498-512 [2021-11-29; online 2021-05-10]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

Fragment-based design of selective GPCR ligands guided by free energy simulations.

Matricon P, Vo DD, Gao ZG, ..., Jacobson KA, Carlsson J

Chem. Commun. (Camb.) 57 (92) 12305-12308 [2021-11-19; online 2021-11-19]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

A network-based approach reveals the dysregulated transcriptional regulation in non-alcoholic fatty liver disease.

Yang H, Arif M, Yuan M, ..., Zhang C, Mardinoglu A

iScience 24 (11) 103222 [2021-11-19; online 2021-10-05]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Single cell genomics reveals plastid-lacking Picozoa are close relatives of red algae.

Schön ME, Zlatogursky VV, Singh RP, ..., Wideman JG, Burki F

Nat Commun 12 (1) 6651 [2021-11-17; online 2021-11-17]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Boron-based hybrids as novel scaffolds for the development of drugs with neuroprotective properties.

Cacciatore I, Turkez H, Di Rienzo A, ..., Mardinoglu A, Di Stefano A

RSC Med Chem 12 (11) 1944-1949 [2021-11-17; online 2021-08-13]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Using High-Sensitivity Lipidomics To Assess Microscale Heterogeneity in Oceanic Sinking Particles and Single Phytoplankton Cells.

Hunter JE, Fredricks HF, Behrendt L, ..., Stocker R, Van Mooy BAS

Environ. Sci. Technol. 55 (22) 15456-15465 [2021-11-16; online 2021-11-01]

Lars Behrendt SciLifeLab Fellow

PubMed DOI Crossref

MapToCleave: High-throughput profiling of microRNA biogenesis in living cells.

Kang W, Fromm B, Houben AJ, ..., Biryukova I, Friedländer MR

Cell Reports 37 (7) 110015 [2021-11-16; online 2021-11-18]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Engineered Human Induced Pluripotent Cells Enable Genetic Code Expansion in Brain Organoids.

van Husen LS, Katsori AM, Meineke B, ..., Schedin-Weiss S, Elsässer SJ

Chembiochem 22 (22) 3208-3213 [2021-11-16; online 2021-09-13]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Allosteric Effect of Nanobody Binding on Ligand-Specific Active States of the β2 Adrenergic Receptor.

Chen Y, Fleetwood O, Pérez-Conesa S, Delemotte L

J Chem Inf Model - (-) - [2021-11-15; online 2021-11-15]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Glucosylceramide synthase deficiency in the heart compromises β1-adrenergic receptor trafficking.

Andersson L, Cinato M, Mardani I, ..., Borén J, Levin MC

Eur. Heart J. 42 (43) 4481-4492 [2021-11-14; online 2021-07-24]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling.

Meineke B, Heimgärtner J, Craig AJ, ..., Moodie LWK, Elsässer SJ

Front Chem 9 (-) 768535 [2021-11-11; online 2021-11-11]

SciLifeLab Fellow Simon Elsässer

DOI Crossref

Large-scale identification of RBP-RNA interactions by RAPseq refines essentials of post-transcriptional gene regulation

Atanasoai I, Papavasileiou S, Preiß N, Kutter C

- - (-) - [2021-11-09; online 2021-11-09]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

OpenPhi: an interface to access Philips iSyntax whole slide images for computational pathology.

Mulliqi N, Kartasalo K, Olsson H, ..., Eklund M, Ruusuvuori P

Bioinformatics 37 (21) 3995-3997 [2021-11-05; online 2021-08-07]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Vesicle Viewer: Online visualization and analysis of small-angle scattering from lipid vesicles.

Lewis-Laurent A, Doktorova M, Heberle FA, Marquardt D

Biophys. J. 120 (21) 4639-4648 [2021-11-02; online 2021-09-24]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF.

Hausmann A, Felmy B, Kunz L, ..., Sellin ME, Hardt WD

J. Exp. Med. 218 (11) - [2021-11-01; online 2021-09-16]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Improving sampling of crystallographic disorder in ensemble refinement.

Ploscariu N, Burnley T, Gros P, Pearce NM

Acta Crystallogr D Struct Biol 77 (Pt 11) 1357-1364 [2021-11-01; online 2021-10-20]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

Safety and Efficacy Assessments to Take Antioxidants in Glioblastoma Therapy: From In Vitro Experiences to Animal and Clinical Studies.

Turkez H, Tozlu OO, Arslan ME, Mardinoglu A

Neurochem Int 150 (-) 105168 [2021-11-00; online 2021-08-25]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Effective sequence similarity detection with strobemers

Sahlin K

Genome Res. 31 (11) 2080-2094 [2021-11-00; online 2021-10-19]

Kristoffer Sahlin SciLifeLab Fellow

PubMed DOI Crossref

Distinction of lymphoid and myeloid clonal hematopoiesis.

Niroula A, Sekar A, Murakami MA, ..., Natarajan P, Ebert BL

Nat. Med. 27 (11) 1921-1927 [2021-11-00; online 2021-10-18]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram.

Biancalani T, Scalia G, Buffoni L, ..., Macosko EZ, Regev A

Nat. Methods 18 (11) 1352-1362 [2021-11-00; online 2021-10-28]

Sanja Vickovic SciLifeLab Fellow

DOI Crossref

Comprehensive analysis of chemical and biological problems associated with browning agents used in aquatic studies

Scharnweber K, Peura S, Attermeyer K, ..., Tranvik LJ, Székely AJ

Limnol Oceanogr Methods - (-) - [2021-10-28; online 2021-10-28]

Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

Revealing the Molecular Mechanisms of Alzheimer's Disease Based on Network Analysis.

Bayraktar A, Lam S, Altay O, ..., Shoaie S, Mardinoglu A

Int J Mol Sci 22 (21) 11556 [2021-10-26; online 2021-10-26]

Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

The Lon protease temporally restricts polar cell differentiation events during the Caulobacter cell cycle.

Omnus DJ, Fink MJ, Szwedo K, Jonas K

Elife 10 (-) - [2021-10-25; online 2021-10-25]

Kristina Jonas SciLifeLab Fellow

PubMed DOI Crossref

Virtual reality for 3D histology: multi-scale visualization of organs with interactive feature exploration.

Liimatainen K, Latonen L, Valkonen M, Kartasalo K, Ruusuvuori P

BMC Cancer 21 (1) 1133 [2021-10-22; online 2021-10-22]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Monitoring the Microevolution of Salmonella enterica in Healthy Dairy Cattle Populations at the Individual Farm Level Using Whole-Genome Sequencing.

Carroll LM, Buehler AJ, Gaballa A, ..., Cheng RA, Wiedmann M

Front Microbiol 12 (-) 763669 [2021-10-18; online 2021-10-18]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Chemoselective and Highly Sensitive Quantification of Gut Microbiome and Human Metabolites.

Lin W, Conway LP, Vujasinovic M, Löhr JM, Globisch D

Angew. Chem. Int. Ed. Engl. 60 (43) 23232-23240 [2021-10-18; online 2021-09-17]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Recent Evolution and Genomic Profile of Salmonella enterica Serovar Heidelberg Isolates from Poultry Flocks in Brazil.

Kipper D, Orsi RH, Carroll LM, ..., Wiedmann M, Lunge VR

Applied and environmental microbiology 87 (21) e0103621 [2021-10-14; online 2021-08-18]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Herpes Simplex Virus 1 and 2 Infections during Differentiation of Human Cortical Neurons.

Bergström P, Trybala E, Eriksson CE, ..., Zetterberg H, Bergström T

Viruses 13 (10) - [2021-10-14; online 2021-10-14]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

The Assessment of Selected miRNA Profile in Familial Mediterranean Fever.

Kahraman CY, Egin ME, Tatar A, Turkez H, Mardinoglu A

Biomed Res Int 2021 (-) 6495700 [2021-10-13; online 2021-10-13]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Characterization of Basal Transcriptomes Identifies Potential Metabolic and Virulence-Associated Adaptations Among Diverse Nontyphoidal Salmonella enterica Serovars.

Cohn AR, Orsi RH, Carroll LM, ..., Wiedmann M, Cheng RA

Front Microbiol 12 (-) 730411 [2021-10-13; online 2021-10-13]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Diversity and ecology of protists revealed by metabarcoding.

Burki F, Sandin MM, Jamy M

Curr. Biol. 31 (19) R1267-R1280 [2021-10-11; online 2021-10-13]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Combined Metabolic Activators Decrease Liver Steatosis by Activating Mitochondrial Metabolism in Hamsters Fed with a High-Fat Diet.

Yang H, Mayneris-Perxachs J, Boqué N, ..., Mardinoglu A, Caimari A

Biomedicines 9 (10) - [2021-10-11; online 2021-10-11]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines.

Lin W, Yang Z, Kaur A, ..., Löhr JM, Globisch D

RSC Chem Biol 2 (5) 1479-1483 [2021-10-07; online 2021-08-12]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Genomic Characterization of Endemic and Ecdemic Non-typhoidal Salmonella enterica Lineages Circulating Among Animals and Animal Products in South Africa.

Carroll LM, Pierneef R, Mathole M, Matle I

Front Microbiol 12 (-) 748611 [2021-10-04; online 2021-10-04]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Predicting Molecular Phenotypes from Histopathology Images: A Transcriptome-Wide Expression-Morphology Analysis in Breast Cancer.

Wang Y, Kartasalo K, Weitz P, ..., Hartman J, Rantalainen M

Cancer Res. 81 (19) 5115-5126 [2021-10-01; online 2021-08-02]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Differential susceptibility of rat primary neurons and neural stem cells to PFOS and PFOA toxicity.

Pierozan P, Karlsson O

Toxicol. Lett. 349 (-) 61-68 [2021-10-01; online 2021-06-11]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?

Ballante F, Kooistra AJ, Kampen S, de Graaf C, Carlsson J

Pharmacol Rev 73 (4) 527-565 [2021-10-00; online 2021-12-16]

Jens Carlsson SciLifeLab Fellow

DOI Crossref

Sinking enhances the degradation of organic particles by marine bacteria

Alcolombri U, Peaudecerf FJ, Fernandez VI, ..., Lee KS, Stocker R

Nat. Geosci. 14 (10) 775-780 [2021-10-00; online 2021-09-23]

Lars Behrendt SciLifeLab Fellow

PubMed DOI Crossref

Refining the amyloid β peptide and oligomer fingerprint ambiguities in Alzheimer's disease: Mass spectrometric molecular characterization in brain, cerebrospinal fluid, blood, and plasma.

Michno W, Blennow K, Zetterberg H, Brinkmalm G

J. Neurochem. 159 (2) 234-257 [2021-10-00; online 2021-07-27]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Promising potential of boron compounds against Glioblastoma: In Vitro antioxidant, anti-inflammatory and anticancer studies.

Turkez H, Arslan ME, Tatar A, Mardinoglu A

Neurochem Int 149 (-) 105137 [2021-10-00; online 2021-07-19]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 9: Polymyxins: colistin.

EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L

EFSA J 19 (10) e06861 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 8: Pleuromutilins: tiamulin and valnemulin.

EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L

EFSA J 19 (10) e06860 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 7: Amphenicols: florfenicol and thiamphenicol.

EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L

EFSA J 19 (10) e06859 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 6: Macrolides: tilmicosin, tylosin and tylvalosin.

EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L

EFSA J 19 (10) e06858 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 5: Lincosamides: lincomycin.

EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L

EFSA J 19 (10) e06856 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 4: β-Lactams: amoxicillin and penicillin V.

EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L

EFSA J 19 (10) e06855 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 3: Amprolium.

EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L

EFSA J 19 (10) e06854 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 2: Aminoglycosides/aminocyclitols: apramycin, paromomycin, neomycin and spectinomycin.

EFSA Panel on Biological Hazards (BIOHAZ) , Allende A, Koutsoumanis K, ..., Stella P, Peixe L

EFSA J 19 (10) e06853 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 1: Methodology, general data gaps and uncertainties.

EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L

EFSA J 19 (10) e06852 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 13: Diaminopyrimidines: trimethoprim.

EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L

EFSA J 19 (10) e06865 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 12: Tetracyclines: tetracycline, chlortetracycline, oxytetracycline, and doxycycline.

EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L

EFSA J 19 (10) e06864 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 11: Sulfonamides.

EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L

EFSA J 19 (10) e06863 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 10: Quinolones: flumequine and oxolinic acid.

EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L

EFSA J 19 (10) e06862 [2021-10-00; online 2021-10-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Corrigendum: Ancient microRNA profiles of 14,300-yr-old canid samples confirm taxonomic origin and provide glimpses into tissue-specific gene regulation from the Pleistocene.

Fromm B, Tarbier M, Smith O, ..., Gilbert MTP, Friedländer MR

RNA 27 (10) 1291 [2021-10-00; online 2021-09-18]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients.

Zeybel M, Altay O, Arif M, ..., Borén J, Mardinoglu A

Mol Syst Biol 17 (10) e10459 [2021-10-00; online 2021-10-26]

Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

Association of levonorgestrel intrauterine devices with stress reactivity, mental health, quality of life and sexual functioning: A systematic review.

Bürger Z, Bucher AM, Comasco E, ..., Kogler L, Derntl B

Front Neuroendocrinol 63 (-) 100943 [2021-10-00; online 2021-08-20]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

A practical guide to large-scale docking.

Bender BJ, Gahbauer S, Luttens A, ..., Irwin JJ, Shoichet BK

Nat Protoc 16 (10) 4799-4832 [2021-10-00; online 2021-09-24]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

An evaluation of a FluoroSpot assay as a diagnostic tool to determine SARS-CoV-2 specific T cell responses.

Mangsbo SM, Havervall S, Laurén I, ..., Klingström J, Thålin C

PLoS ONE 16 (9) e0258041 [2021-09-30; online 2021-09-30]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Morphological Features Extracted by AI Associated with Spatial Transcriptomics in Prostate Cancer.

Chelebian E, Avenel C, Kartasalo K, ..., Lundeberg J, Wählby C

Cancers (Basel) 13 (19) - [2021-09-28; online 2021-09-28]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Improved Radiolytic Stability of a 68Ga-labelled Collagelin Analogue for the Imaging of Fibrosis.

Velikyan I, Rosenström U, Rosestedt M, Eriksson O, Antoni G

Pharmaceuticals (Basel, Switzerland) 14 (10) - [2021-09-28; online 2021-09-28]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Inferring Genome-Wide Correlations of Mutation Fitness Effects between Populations.

Huang X, Fortier AL, Coffman AJ, ..., Ragsdale AP, Gutenkunst RN

Mol. Biol. Evol. 38 (10) 4588-4602 [2021-09-27; online 2021-05-28]

DDLS Fellow Jennifer James

PubMed DOI Crossref

Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69.

Persson J, Puuvuori E, Zhang B, ..., Eriksson O, Löfblom J

Sci Rep 11 (1) 19151 [2021-09-27; online 2021-09-27]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer's and Parkinson's Diseases.

Lam S, Hartmann N, Benfeitas R, ..., Knight R, Mardinoglu A

Biomedicines 9 (10) - [2021-09-24; online 2021-09-24]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Optimization of an Imidazo[1,2-a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy.

McCoull W, Boyd S, Brown MR, ..., Zhu Q, Smith PD

J Med Chem 64 (18) 13524-13539 [2021-09-23; online 2021-09-03]

SciLifeLab Fellow Yumeng Mao

PubMed DOI Crossref

Using informative features in machine learning based method for COVID-19 drug repurposing.

Aghdam R, Habibi M, Taheri G

J Cheminform 13 (1) 70 [2021-09-20; online 2021-09-20]

DDLS Fellow Golnaz Taheri

PubMed DOI Crossref

A method for intuitively extracting macromolecular dynamics from structural disorder

Pearce NM, Gros P

Nat Commun 12 (1) 5493 [2021-09-17; online 2021-09-17]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

A nascent polypeptide sequence modulates DnaA translation elongation in response to nutrient availability.

Felletti M, Romilly C, Wagner EGH, Jonas K

Elife 10 (-) - [2021-09-15; online 2021-09-15]

Kristina Jonas SciLifeLab Fellow

PubMed DOI Crossref

Selection on accessible chromatin regions in Capsella grandiflora.

Horvath R, Josephs EB, Pesquet E, ..., Scofield D, Slotte T

Mol. Biol. Evol. - (-) - [2021-09-08; online 2021-09-08]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells.

von Beek C, Alriksson L, Palle J, ..., Sellin ME, Pejler G

PLoS ONE 16 (9) e0256708 [2021-09-07; online 2021-09-07]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome.

Bacic L, Gaullier G, Sabantsev A, ..., Boulton SJ, Deindl S

Elife 10 (-) - [2021-09-06; online 2021-09-06]

SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Association of Diet Quality With Prevalence of Clonal Hematopoiesis and Adverse Cardiovascular Events.

Bhattacharya R, Zekavat SM, Uddin MM, ..., Bick A, Natarajan P

JAMA Cardiol 6 (9) 1069-1077 [2021-09-01; online 2021-06-10]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

ZBTB33 is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing.

Beauchamp EM, Leventhal M, Bernard E, ..., Jaiswal S, Ebert BL

Blood Cancer Discov 2 (5) 500-517 [2021-09-00; online 2021-07-14]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

The long-time orphan protist Meringosphaera mediterranea Lohmann, 1902 [1903] is a centrohelid heliozoan.

Zlatogursky VV, Shɨshkin Y, Drachko D, Burki F

J. Eukaryot. Microbiol. 68 (5) e12860 [2021-09-00; online 2021-07-12]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

RecA finds homologous DNA by reduced dimensionality search.

Wiktor J, Gynnå AH, Leroy P, ..., Testa I, Elf J

Nature 597 (7876) 426-429 [2021-09-00; online 2021-09-01]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia.

Draper-Joyce CJ, Bhola R, Wang J, ..., Imlach WL, Christopoulos A

Nature 597 (7877) 571-576 [2021-09-00; online 2021-09-08]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Killing two enemies with one stone? Genomics of resistance to two sympatric pathogens in Norway spruce.

Capador-Barreto HD, Bernhardsson C, Milesi P, ..., Stenlid J, Elfstrand M

Mol. Ecol. 30 (18) 4433-4447 [2021-09-00; online 2021-08-05]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19.

Altay O, Arif M, Li X, ..., Uhlén M, Mardinoglu A

Adv Sci (Weinh) 8 (17) e2101222 [2021-09-00; online 2021-06-28]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Synergies of Systems Biology and Synthetic Biology in Human Microbiome Studies.

Ezzamouri B, Shoaie S, Ledesma-Amaro R

Front Microbiol 12 (-) 681982 [2021-08-31; online 2021-08-31]

Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

Not4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5A.

Allen GE, Panasenko OO, Villanyi Z, ..., Ignatova Z, Collart MA

Cell Reports 36 (9) 109633 [2021-08-31; online 2021-09-02]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Convolutional Neural Networks as Summary Statistics for Approximate Bayesian Computation.

Akesson M, Singh P, Wrede F, Hellander A

IEEE/ACM Trans Comput Biol Bioinform PP (-) - [2021-08-30; online 2021-08-30]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

TET2 as a tumor suppressor and therapeutic target in T-cell acute lymphoblastic leukemia.

Bensberg M, Rundquist O, Selimović A, ..., Lentini A, Nestor CE

Proc. Natl. Acad. Sci. U.S.A. 118 (34) - [2021-08-24; online 2021-08-21]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

Structure and Sequence-based Computational Approaches to Allosteric Signal Transduction: Application to Electromechanical Coupling in Voltage-gated Ion Channels.

Elbahnsi A, Delemotte L

J. Mol. Biol. 433 (17) 167095 [2021-08-20; online 2021-06-06]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5.

Galleano I, Harms H, Choudhury K, ..., Delemotte L, Pless SA

Proc. Natl. Acad. Sci. U.S.A. 118 (33) - [2021-08-17; online 2021-08-11]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Advances in the Relationships Between Cow's Milk Protein Allergy and Gut Microbiota in Infants.

Yang Y, Li X, Yang Y, ..., Ji B, Wei Y

Front Microbiol 12 (-) 716667 [2021-08-16; online 2021-08-16]

Saeed Shoaie SciLifeLab Fellow

DOI Crossref

ImSwitch: Generalizing microscope control in Python

Moreno X, Al-Kadhimi S, Alvelid J, Bodén A, Testa I

JOSS 6 (64) 3394 [2021-08-14; online 2021-08-14]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Candidatus Methylumidiphilus Drives Peaks in Methanotrophic Relative Abundance in Stratified Lakes and Ponds Across Northern Landscapes.

Martin G, Rissanen AJ, Garcia SL, ..., Buck M, Peura S

Front Microbiol 12 (-) 669937 [2021-08-12; online 2021-08-12]

Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation.

Pagnon de la Vega M, Giedraitis V, Michno W, ..., Sehlin D, Ingelsson M

Sci Transl Med 13 (606) - [2021-08-11; online 2021-08-13]

SciLifeLab Fellow Wojciech Michno

DOI Crossref

Neuronal mimicry generates an ecosystem critical for brain metastatic growth of SCLC

Qu F, Cao S, Michno W, ..., Paşca AM, Sage J

- - (-) - [2021-08-10; online 2021-08-10]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Structure-Guided Design of G-Protein-Coupled Receptor Polypharmacology.

Kampen S, Duy Vo D, Zhang X, ..., Kihlberg J, Carlsson J

Angew. Chem. Int. Ed. Engl. 60 (33) 18022-18030 [2021-08-09; online 2021-07-16]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Sample-to-answer COVID-19 nucleic acid testing using a low-cost centrifugal microfluidic platform with bead-based signal enhancement and smartphone read-out.

Soares RRG, Akhtar AS, Pinto IF, ..., Pelechano V, Russom A

Lab Chip 21 (15) 2932-2944 [2021-08-07; online 2021-06-11]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Genome assemblies of three closely related leaf beetle species (Galerucella spp.).

Yang X, Slotte T, Dainat J, Hambäck PA

G3 11 (8) - [2021-08-07; online 2021-12-02]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Lysine demethylase LSD1 delivered via small extracellular vesicles promotes gastric cancer cell stemness.

Zhao LJ, Li YY, Zhang YT, ..., Zheng YC, Liu HM

EMBO Rep. 22 (8) e50922 [2021-08-04; online 2021-05-31]

Adil Mardinoglu SciLifeLab Fellow

DOI Crossref

Microbial retention and resistances in stormwater quality improvement devices treating road runoff

Liguori R, Rommel SH, Bengtsson-Palme J, Helmreich B, Wurzbacher C

FEMS Microbes 2 (-) - [2021-08-03; online 2021-07-22]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Response to Lai.

Wang QL, Lagergren J

Am J Gastroenterol 116 (8) 1758 [2021-08-01; online 2021-05-25]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output.

Kanellis DC, Espinoza JA, Zisi A, ..., Lindström MS, Bartek J

Sci Adv 7 (32) - [2021-08-00; online 2021-08-04]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

The emerging role of artificial intelligence in the reporting of prostate pathology.

Egevad L, Delahunt B, Samaratunga H, ..., Kartasalo K, Eklund M

Pathology 53 (5) 565-567 [2021-08-00; online 2021-06-06]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Structure and Interdigitation of Chain-Asymmetric Phosphatidylcholines and Milk Sphingomyelin in the Fluid Phase.

Frewein MPK, Doktorova M, Heberle FA, ..., Porcar L, Pabst G

Symmetry (Basel) 13 (8) - [2021-08-00; online 2021-08-05]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Rpb4 and Puf3 imprint and post-transcriptionally control the stability of a common set of mRNAs in yeast.

Garrido-Godino AI, Gupta I, Gutiérrez-Santiago F, ..., Pelechano V, Navarro F

RNA Biol 18 (8) 1206-1220 [2021-08-00; online 2020-11-01]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

PhyloFisher: A phylogenomic package for resolving eukaryotic relationships.

Tice AK, Žihala D, Pánek T, ..., Kolísko M, Brown MW

PLoS Biol. 19 (8) e3001365 [2021-08-00; online 2021-08-06]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Model Membrane Systems Used to Study Plasma Membrane Lipid Asymmetry.

Scott HL, Kennison KB, Enoki TA, ..., Heberle FA, Katsaras J

Symmetry (Basel) 13 (8) - [2021-08-00; online 2021-07-26]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

In vitro neuroprotective effects of farnesene sesquiterpene on alzheimer's disease model of differentiated neuroblastoma cell line.

Arslan ME, Türkez H, Mardinoğlu A

Int J Neurosci 131 (8) 745-754 [2021-08-00; online 2020-04-19]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Getting a grip with kirigami.

Teleki A, Artursson P

Nat Mater 20 (8) 1043-1044 [2021-08-00; online 2021-07-30]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

Aggregation and mobility of membrane proteins interplay with local lipid order in the plasma membrane of T cells.

Urbančič I, Schiffelers L, Jenkins E, ..., Sezgin E, Eggeling C

FEBS Lett. 595 (16) 2127-2146 [2021-08-00; online 2021-07-07]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Topological network based drug repurposing for coronavirus 2019.

Habibi M, Taheri G

PLoS ONE 16 (7) e0255270 [2021-07-29; online 2021-07-29]

DDLS Fellow Golnaz Taheri

PubMed DOI Crossref

ADP-ribosyltransferases, an update on function and nomenclature.

Lüscher B, Ahel I, Altmeyer M, ..., Zaja R, Ziegler M

FEBS J. - (-) - [2021-07-29; online 2021-07-29]

SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Somatic Copy Number Alterations in Human Cancers: An Analysis of Publicly Available Data From The Cancer Genome Atlas.

Harbers L, Agostini F, Nicos M, ..., Bienko M, Crosetto N

Front Oncol 11 (-) 700568 [2021-07-28; online 2021-07-28]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

DNA methylation of Vesicular Glutamate Transporters in the mesocorticolimbic brain following early-life stress and adult ethanol exposure-an explorative study.

Vrettou M, Yan L, Nilsson KW, ..., Nylander I, Comasco E

Sci Rep 11 (1) 15322 [2021-07-28; online 2021-07-28]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Anticancer effects of novel NSAIDs derivatives on cultured human glioblastoma cells.

Özdemir Ö, Marinelli L, Cacciatore I, ..., Mardinoglu A, Turkez H

Z Naturforsch C J Biosci 76 (7-8) 329-335 [2021-07-27; online 2020-09-05]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning.

Li X, Kim W, Juszczak K, ..., Zhang C, Mardinoglu A

iScience 24 (7) 102722 [2021-07-23; online 2021-06-12]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Differential regulation of oxidative stress, microbiota-derived, and energy metabolites in the mouse brain during sleep.

Vallianatou T, Lin W, Bèchet NB, ..., Lundgaard I, Globisch D

J. Cereb. Blood Flow Metab. - (-) 271678X211033358 [2021-07-22; online 2021-07-22]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Recent Progress in the Molecular Imaging of Nonalcoholic Fatty Liver Disease.

Wegrzyniak O, Rosestedt M, Eriksson O

Int J Mol Sci 22 (14) - [2021-07-08; online 2021-07-08]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis.

Kundu S, Ali MA, Handin N, ..., Globisch D, Sjöblom T

J. Exp. Clin. Cancer Res. 40 (1) 225 [2021-07-07; online 2021-07-07]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure.

Yu B, Roberts MB, Raffield LM, ..., Eaton CB, National Heart, Lung, and Blood Institute TOPMed Consortium

J. Am. Coll. Cardiol. 78 (1) 42-52 [2021-07-06; online 2021-07-03]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

iNetModels 2.0: an interactive visualization and database of multi-omics data.

Arif M, Zhang C, Li X, ..., Uhlen M, Mardinoglu A

Nucleic Acids Res. 49 (W1) W271-W276 [2021-07-02; online 2021-04-14]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

The Effect of the Molecular Weight of Polyvinylpyrrolidone and the Model Drug on Laser-Induced In Situ Amorphization.

Hempel NJ, Merkl P, Knopp MM, ..., Sotiriou GA, Löbmann K

Molecules 26 (13) 4035 [2021-07-01; online 2021-07-01]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

Editorial: NK-Myeloid Cell Interactions in the Tumor Microenvironment: Implications for Cancer Immunotherapy.

Wennerberg E, Lundqvist A, Mao Y, Mougiakakos D

Front Immunol 12 (-) 718844 [2021-07-01; online 2021-07-01]

SciLifeLab Fellow Yumeng Mao

PubMed DOI Crossref

Simultaneous detection of SARS-CoV-2 and pandemic (H1N1) 2009 virus with real-time isothermal platform.

Yu L, Wang J, Li X, ..., Guo X, Yin X

Heliyon 7 (7) e07584 [2021-07-00; online 2021-07-15]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Safety Assessments of Nickel Boride Nanoparticles on the Human Pulmonary Alveolar Cells by Using Cell Viability and Gene Expression Analyses.

Türkez H, Arslan ME, Sönmez E, ..., Açikyildiz M, Mardinoğlu A

Biol Trace Elem Res 199 (7) 2602-2611 [2021-07-00; online 2020-09-09]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

STED and parallelized RESOLFT optical nanoscopy of the tubular endoplasmic reticulum and its mitochondrial contacts in neuronal cells.

Damenti M, Coceano G, Pennacchietti F, Bodén A, Testa I

Neurobiol. Dis. 155 (-) 105361 [2021-07-00; online 2021-04-12]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Recommendations for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samples.

Kubik S, Marques AC, Xing X, ..., Willig A, Xu Z

Clin. Microbiol. Infect. 27 (7) 1036.e1-1036.e8 [2021-07-00; online 2021-04-02]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

On the origin of the widespread self-compatible allotetraploid Capsella bursa-pastoris (Brassicaceae).

Bachmann JA, Tedder A, Fracassetti M, ..., Köhler C, Slotte T

Heredity (Edinb) 127 (1) 124-134 [2021-07-00; online 2021-04-19]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Molecular Dynamics Simulations of Ion Channels.

Carnevale V, Delemotte L, Howard RJ

Trends Biochem. Sci. 46 (7) 621-622 [2021-07-00; online 2021-04-30]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Effects of 6 weeks of treatment with dapagliflozin, a sodium-glucose co-transporter-2 inhibitor, on myocardial function and metabolism in patients with type 2 diabetes: A randomized, placebo-controlled, exploratory study.

Oldgren J, Laurila S, Åkerblom A, ..., Oscarsson J, Nuutila P

Diabetes Obes Metab 23 (7) 1505-1517 [2021-07-00; online 2021-03-12]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Distinct genetic regions are associated with differential population susceptibility to chemical exposures.

Kosnik MB, Enroth S, Karlsson O

Environ Int 152 (-) 106488 [2021-07-00; online 2021-03-10]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

DNA Origami Penetration in Cell Spheroid Tissue Models is Enhanced by Wireframe Design.

Wang Y, Benson E, Fördős F, ..., Teixeira AI, Högberg B

Adv. Mater. Weinheim 33 (29) e2008457 [2021-07-00; online 2021-06-06]

Erik Benson SciLifeLab Fellow

PubMed DOI Crossref

Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator.

Kaltsouni E, Fisher PM, Dubol M, ..., Comasco E, Sundström-Poromaa I

Neuropsychopharmacology 46 (8) 1460-1467 [2021-07-00; online 2021-04-29]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Artificial Intelligence for Diagnosis and Gleason Grading of Prostate Cancer in Biopsies-Current Status and Next Steps.

Kartasalo K, Bulten W, Delahunt B, ..., Egevad L, Eklund M

Eur Urol Focus 7 (4) 687-691 [2021-07-00; online 2021-08-12]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

A single-cell type transcriptomics map of human tissues.

Karlsson M, Zhang C, Méar L, ..., Uhlén M, Lindskog C

Sci Adv 7 (31) - [2021-07-00; online 2021-07-28]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

DNA Blocks the Lethal Effect of Human Beta-Defensin 2 Against Neisseria meningitidis.

Wassing GM, Lidberg K, Sigurlásdóttir S, ..., Jonas K, Jonsson AB

Front Microbiol 12 (-) 697232 [2021-06-30; online 2021-06-30]

Kristina Jonas SciLifeLab Fellow

PubMed DOI Crossref

Cisplatin inhibits frequency and suppressive activity of monocytic myeloid-derived suppressor cells in cancer patients.

Van Wigcheren GF, De Haas N, Mulder TA, ..., Hato SV, De Vries IJM

Oncoimmunology 10 (1) 1935557 [2021-06-27; online 2021-06-27]

SciLifeLab Fellow Yumeng Mao

PubMed DOI Crossref

Pesticide-induced multigenerational effects on amphibian reproduction and metabolism.

Karlsson O, Svanholm S, Eriksson A, ..., Jernerén F, Berg C

Sci. Total Environ. 775 (-) 145771 [2021-06-25; online 2021-02-11]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

COVseq is a cost-effective workflow for mass-scale SARS-CoV-2 genomic surveillance.

Simonetti M, Zhang N, Harbers L, ..., Ghisetti V, Crosetto N

Nat Commun 12 (1) 3903 [2021-06-23; online 2021-06-23]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Accelerated regression-based summary statistics for discrete stochastic systems via approximate simulators.

Jiang RM, Wrede F, Singh P, Hellander A, Petzold LR

BMC Bioinformatics 22 (1) 339 [2021-06-23; online 2021-06-23]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

The Influence of Drug–Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles

Hempel NJ, Merkl P, Knopp MM, ..., Sotiriou GA, Löbmann K

Pharmaceutics 13 (6) 917 [2021-06-21; online 2021-06-21]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

Application of high-throughput 5'P sequencing for the study of co-translational mRNA decay.

Zhang Y, Pelechano V

STAR Protoc 2 (2) 100447 [2021-06-18; online 2021-03-31]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2.

Roxhed N, Bendes A, Dale M, ..., Fredolini C, Schwenk JM

Nat Commun 12 (1) 3695 [2021-06-17; online 2021-06-17]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Means, Motive, and Opportunity: Do Non-Islet-Reactive Infiltrating T Cells Contribute to Autoimmunity in Type 1 Diabetes?

Rodriguez-Calvo T, Christoffersson G, Bender C, ..., Kent SC, James EA

Front Immunol 12 (-) 683091 [2021-06-16; online 2021-06-16]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Prognostic implications of troponin T variations in inherited cardiomyopathies using systems biology.

Shakur R, Ochoa JP, Robinson AJ, ..., Vihinen M, Monserrat L

NPJ Genom Med 6 (1) 47 [2021-06-14; online 2021-06-14]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Bicyclic β-Sheet Mimetics that Target the Transcriptional Coactivator β-Catenin and Inhibit Wnt Signaling.

Wendt M, Bellavita R, Gerber A, ..., Hennig S, Grossmann TN

Angew. Chem. Int. Ed. Engl. 60 (25) 13937-13944 [2021-06-14; online 2021-05-05]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

Leveraging breeding programs and genomic data in Norway spruce (Picea abies L. Karst) for GWAS analysis.

Chen ZQ, Zan Y, Milesi P, ..., Lascoux M, Wu HX

Genome Biol. 22 (1) 179 [2021-06-13; online 2021-06-13]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet

Hempel NJ, Merkl P, Asad S, ..., Sotiriou GA, Löbmann K

Mol. Pharmaceutics 18 (6) 2254-2262 [2021-06-07; online 2021-05-05]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function.

Oftedal BE, Maio S, Handel AE, ..., Maizels RM, Holländer GA

Commun Biol 4 (1) 681 [2021-06-03; online 2021-06-03]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Imaging of the Glucagon Receptor in Subjects with Type 2 Diabetes.

Eriksson O, Velikyan I, Haack T, ..., Tillner J, Wagner M

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 62 (6) 833-838 [2021-06-01; online 2020-10-23]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Unboxing mutations: Connecting mutation types with evolutionary consequences.

Berdan EL, Blanckaert A, Slotte T, ..., Westram AM, Fragata I

Mol. Ecol. 30 (12) 2710-2723 [2021-06-00; online 2021-05-19]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Towards policies that capture the expected value of biomolecular diversity for drug discovery, human health, and well-being.

Pesic M, Egamberdieva D, Kolodziejczyk B, ..., Neergheen VS, Kagansky A

Biol Futur 72 (2) 119-125 [2021-06-00; online 2020-09-07]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

More Than Just Letters and Chemistry: Genomics Goes Mechanics.

Deindl S, Elf J

Trends Biochem. Sci. 46 (6) 431-432 [2021-06-00; online 2021-04-12]

SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Interobserver reproducibility of perineural invasion of prostatic adenocarcinoma in needle biopsies.

Egevad L, Delahunt B, Samaratunga H, ..., Eklund M, Ruusuvuori P

Virchows Arch. 478 (6) 1109-1116 [2021-06-00; online 2021-02-03]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells.

Erdem C, Lee AV, Taylor DL, Lezon TR

PLoS Comput Biol 17 (6) e1009125 [2021-06-00; online 2021-06-30]

Cemal Erdem DDLS Fellow

PubMed DOI Crossref

Following spatial Aβ aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics.

Michno W, Stringer KM, Enzlein T, ..., Edwards FA, Hanrieder J

Sci Adv 7 (25) - [2021-06-00; online 2021-06-16]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides.

Muntjewerff EM, Tang K, Lutter L, ..., van den Bogaart G, Mahata SK

Acta Physiol 232 (2) e13655 [2021-06-00; online 2021-05-06]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source.

Douangamath A, Powell A, Fearon D, ..., Gorrie-Stone T, von Delft F

J Vis Exp - (171) - [2021-05-29; online 2021-05-29]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

Using TIF-Seq2 to investigate association between 5´ and 3´mRNA ends.

Li B, Marques S, Wang J, Pelechano V

Meth. Enzymol. 655 (-) 85-118 [2021-05-28; online 2021-05-28]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Perivascular Macrophages Regulate Blood Flow Following Tissue Damage.

Vågesjö E, Parv K, Ahl D, ..., Christoffersson G, Phillipson M

Circ. Res. 128 (11) 1694-1707 [2021-05-28; online 2021-04-21]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Editorial: Application of Systems Biology in Molecular Characterization and Diagnosis of Cancer.

Zhang C, Wei Y, Mardinoglu A, Zhang P

Front Mol Biosci 8 (-) 668146 [2021-05-28; online 2021-05-28]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Phagocytosis and Efferocytosis by Resident Macrophages in the Mouse Pancreas.

Parv K, Westerlund N, Merchant K, ..., Lindsay RS, Christoffersson G

Front Endocrinol (Lausanne) 12 (-) 606175 [2021-05-25; online 2021-05-25]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives.

Bohutínská M, Vlček J, Yair S, ..., Slotte T, Kolář F

Proc. Natl. Acad. Sci. U.S.A. 118 (21) - [2021-05-25; online 2021-05-19]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

A combined approach for single-cell mRNA and intracellular protein expression analysis.

Reimegård J, Tarbier M, Danielsson M, ..., Friedländer MR, Gallant CJ

Commun Biol 4 (1) 624 [2021-05-25; online 2021-05-25]

DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow

PubMed DOI Crossref

Microbial Community Interactions Are Sensitive to Small Changes in Temperature.

Burman E, Bengtsson-Palme J

Front Microbiol 12 (-) 672910 [2021-05-21; online 2021-05-21]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Reply to Nagle et al.: The universal stiffening effects of cholesterol on lipid membranes.

Ashkar R, Doktorova M, Heberle FA, ..., Khelashvili G, Brown MF

Proc. Natl. Acad. Sci. U.S.A. 118 (20) - [2021-05-18; online 2021-05-07]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

The human exposome and health in the Anthropocene.

Karlsson O, Rocklöv J, Lehoux AP, ..., Blunt MJ, Birnbaum LS

Int J Epidemiol 50 (2) 378-389 [2021-05-17; online 2020-12-23]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

Phylogenomic Insights into the Origin of Primary Plastids.

Irisarri I, Strassert JFH, Burki F

Syst. Biol. - (-) - [2021-05-14; online 2021-05-14]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Comprehensive dataset of shotgun metagenomes from oxygen stratified freshwater lakes and ponds.

Buck M, Garcia SL, Fernandez L, ..., Bertilsson S, Peura S

Sci Data 8 (1) 131 [2021-05-14; online 2021-05-14]

Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

Informing Pharmacokinetic Models With Physiological Data: Oral Population Modeling of L-Serine in Humans.

Bosley JR, Björnson E, Zhang C, ..., Borén J, Mardinoglu A

Front. Pharmacol. 12 (-) 643179 [2021-05-13; online 2021-05-13]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Comparative Genomics Analysis of Keratin-Degrading Chryseobacterium Species Reveals Their Keratinolytic Potential for Secondary Metabolite Production

Kang D, Shoaie S, Jacquiod S, Sørensen SJ, Ledesma-Amaro R

Microorganisms 9 (5) 1042 [2021-05-12; online 2021-05-12]

Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction.

Arif M, Klevstig M, Benfeitas R, ..., Mardinoglu A, Boren J

Elife 10 (-) - [2021-05-11; online 2021-05-11]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Freshwater Chlorobia Exhibit Metabolic Specialization among Cosmopolitan and Endemic Populations.

Garcia SL, Mehrshad M, Buck M, ..., Greening C, Peura S

mSystems 6 (3) - [2021-05-11; online 2021-05-11]

Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

The Genomic Architecture and Evolutionary Fates of Supergenes.

Gutiérrez-Valencia J, Hughes PW, Berdan EL, Slotte T

Genome Biol Evol 13 (5) - [2021-05-07; online 2021-03-20]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Environmental Enrichment Induces Epigenomic and Genome Organization Changes Relevant for Cognition.

Espeso-Gil S, Holik AZ, Bonnin S, ..., Hor CN, Ossowski S

Front Mol Neurosci 14 (-) 664912 [2021-05-05; online 2021-05-05]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

The Chaperonin GroESL Facilitates Caulobacter crescentus Cell Division by Supporting the Functions of the Z-Ring Regulators FtsA and FzlA.

Schroeder K, Heinrich K, Neuwirth I, Jonas K

MBio 12 (3) - [2021-05-04; online 2021-05-04]

Kristina Jonas SciLifeLab Fellow

DOI Crossref

Accuratede novoidentification of biosynthetic gene clusters with GECCO

Carroll LM, Larralde M, Fleck JS, ..., Cappio E, Zeller G

- - (-) - [2021-05-04; online 2021-05-04]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

A microscopy-compatible temperature regulation system for single-cell phenotype analysis - demonstrated by thermoresponse mapping of microalgae.

Andersson M, Johansson S, Bergman H, ..., Behrendt L, Tenje M

Lab Chip 21 (9) 1694-1705 [2021-05-04; online 2021-05-06]

Lars Behrendt SciLifeLab Fellow

PubMed DOI Crossref

Keeping up with the Bacillus cereus group: taxonomy through the genomics era and beyond.

Carroll LM, Cheng RA, Wiedmann M, Kovac J

Crit Rev Food Sci Nutr 62 (28) 7677-7702 [2021-05-03; online 2021-05-03]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity.

Ghovanloo MR, Choudhury K, Bandaru TS, ..., Goodchild SJ, Ruben PC

J. Gen. Physiol. 153 (5) - [2021-05-03; online 2021-04-10]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Volumetric live cell imaging with three-dimensional parallelized RESOLFT microscopy.

Bodén A, Pennacchietti F, Coceano G, ..., Ratz M, Testa I

Nat. Biotechnol. 39 (5) 609-618 [2021-05-00; online 2021-01-11]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Strategies for Constructing and Operating DNA Origami Linear Actuators.

Benson E, Carrascosa Marzo R, Bath J, Turberfield AJ

Small 17 (20) e2007704 [2021-05-00; online 2021-05-04]

Erik Benson SciLifeLab Fellow

PubMed DOI Crossref

High-throughput 5′P sequencing enables the study of degradation-associated ribosome stalls

Zhang Y, Pelechano V

Cell Rep Methods 1 (1) 100001 [2021-05-00; online 2021-05-00]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Epithelium-autonomous NAIP/NLRC4 prevents TNF-driven inflammatory destruction of the gut epithelial barrier in Salmonella-infected mice.

Fattinger SA, Geiser P, Samperio Ventayol P, ..., Hardt WD, Sellin ME

Mucosal Immunol 14 (3) 615-629 [2021-05-00; online 2021-03-17]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Can molecular dynamics simulations improve the structural accuracy and virtual screening performance of GPCR models?

Kapla J, Rodríguez-Espigares I, Ballante F, Selent J, Carlsson J

PLoS Comput Biol 17 (5) e1008936 [2021-05-00; online 2021-05-13]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

The Protein Quality Control Network in Caulobacter crescentus.

Schroeder K, Jonas K

Front Mol Biosci 8 (-) 682967 [2021-04-30; online 2021-04-30]

Kristina Jonas SciLifeLab Fellow

PubMed DOI Crossref

A SARS-CoV-2 (COVID-19) biological network to find targets for drug repurposing.

Habibi M, Taheri G, Aghdam R

Sci Rep 11 (1) 9378 [2021-04-30; online 2021-04-30]

DDLS Fellow Golnaz Taheri

PubMed DOI Crossref

Long-read-sequenced reference genomes of the seven major lineages of enterotoxigenic Escherichia coli (ETEC) circulating in modern time.

von Mentzer A, Blackwell GA, Pickard D, ..., Dougan G, Sjöling Å

Sci Rep 11 (1) 9256 [2021-04-29; online 2021-04-29]

Astrid von Mentzer DDLS Fellow

PubMed DOI Crossref

Informing NMR experiments with molecular dynamics simulations to characterize the dominant activated state of the KcsA ion channel.

Pérez-Conesa S, Keeler EG, Zhang D, Delemotte L, McDermott AE

J Chem Phys 154 (16) 165102 [2021-04-28; online 2021-05-05]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

How Does Liquid-Liquid Phase Separation in Model Membranes Reflect Cell Membrane Heterogeneity?

Sych T, Gurdap CO, Wedemann L, Sezgin E

Membranes (Basel) 11 (5) - [2021-04-28; online 2021-04-28]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI.

van der Kolk BW, Saari S, Lovric A, ..., Pajukanta P, Pietiläinen KH

Cell Rep Med 2 (4) 100226 [2021-04-20; online 2021-03-30]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers.

Samperio Ventayol P, Geiser P, Di Martino ML, ..., Eriksson J, Sellin ME

Proc. Natl. Acad. Sci. U.S.A. 118 (16) - [2021-04-20; online 2021-04-14]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Scalable machine learning-assisted model exploration and inference using Sciope.

Singh P, Wrede F, Hellander A

Bioinformatics 37 (2) 279-281 [2021-04-19; online 2020-07-25]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Germline variants at SOHLH2 influence multiple myeloma risk.

Duran-Lozano L, Thorleifsson G, Lopez de Lapuente Portilla A, ..., Stefansson K, Nilsson B

Blood Cancer J 11 (4) 76 [2021-04-19; online 2021-04-19]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

PET Imaging of GPR44 by Antagonist [11C]MK-7246 in Pigs.

Cheung P, Zhang B, Puuvuori E, ..., Eriksson J, Eriksson O

Biomedicines 9 (4) - [2021-04-16; online 2021-04-16]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Stress-induced transcriptional memory accelerates promoter-proximal pause release and decelerates termination over mitotic divisions.

Vihervaara A, Mahat DB, Himanen SV, ..., Lis JT, Sistonen L

Mol. Cell 81 (8) 1715-1731.e6 [2021-04-15; online 2021-03-29]

Anniina Vihervaara SciLifeLab Fellow

PubMed DOI Crossref

A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation.

Regadas I, Dahlberg O, Vaid R, ..., Wen J, Mannervik M

Mol. Cell 81 (8) 1766-1780.e10 [2021-04-15; online 2021-02-24]

SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

DNA methylation in cord blood in association with prenatal depressive symptoms.

Kallak TK, Bränn E, Fransson E, ..., Lyle R, Skalkidou A

Clin Epigenetics 13 (1) 78 [2021-04-12; online 2021-04-12]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Revealing the Metabolic Alterations during Biofilm Development of Burkholderia cenocepacia Based on Genome-Scale Metabolic Modeling.

Altay O, Zhang C, Turkez H, ..., Uhlén M, Mardinoglu A

Metabolites 11 (4) - [2021-04-05; online 2021-04-05]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Resin-acid derivatives bind to multiple sites on the voltage-sensor domain of the Shaker potassium channel.

Silverå Ejneby M, Gromova A, Ottosson NE, ..., Elinder F, Delemotte L

J. Gen. Physiol. 153 (4) - [2021-04-05; online 2021-03-09]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Genome Size Reduction and Transposon Activity Impact tRNA Gene Diversity While Ensuring Translational Stability in Birds.

Ottenburghs J, Geng K, Suh A, Kutter C

Genome Biol Evol 13 (4) - [2021-04-05; online 2021-02-04]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

The genome of Draba nivalis shows signatures of adaptation to the extreme environmental stresses of the Arctic.

Nowak MD, Birkeland S, Mandáková T, ..., Lysak MA, Brochmann C

Mol Ecol Resour 21 (3) 661-676 [2021-04-00; online 2020-11-12]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Longitudinal Assessment of 11C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes.

Espes D, Carlsson PO, Selvaraju RK, ..., Korsgren O, Eriksson O

Diabetes 70 (4) 966-975 [2021-04-00; online 2021-01-21]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography.

Manell E, Puuvuori E, Svensson A, ..., Jensen Waern M, Eriksson O

BMJ Open Diabetes Res Care 9 (1) - [2021-04-00; online 2021-04-28]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Drug Occupancy Assessment at the Glucose-Dependent Insulinotropic Polypeptide Receptor by Positron Emission Tomography.

Eriksson O, Velikyan I, Haack T, ..., Pierrou S, Wagner M

Diabetes 70 (4) 842-853 [2021-04-00; online 2021-02-05]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Development and Validation of a Risk Prediction Model for Esophageal Squamous Cell Carcinoma Using Cohort Studies.

Wang QL, Ness-Jensen E, Santoni G, Xie SH, Lagergren J

Am J Gastroenterol 116 (4) 683-691 [2021-04-00; online 2021-05-14]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

A genomic catalog of Earth's microbiomes.

Nayfach S, Roux S, Seshadri R, ..., Kyrpides NC, Eloe-Fadrosh EA

Nat. Biotechnol. 39 (4) 499-509 [2021-04-00; online 2020-11-09]

Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

A molecular timescale for eukaryote evolution with implications for the origin of red algal-derived plastids.

Strassert JFH, Irisarri I, Williams TA, Burki F

Nat Commun 12 (1) 1879 [2021-03-25; online 2021-03-25]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Addressing the heterogeneity in liver diseases using biological networks.

Lam S, Doran S, Yuksel HH, ..., Uhlen M, Mardinoglu A

Brief. Bioinformatics 22 (2) 1751-1766 [2021-03-22; online 2020-03-24]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Dysbiosis of the Human Oral Microbiome During the Menstrual Cycle and Vulnerability to the External Exposures of Smoking and Dietary Sugar.

Bostanci N, Krog MC, Hugerth LW, ..., Nielsen HS, Schuppe-Koistinen I

Front. Cell. Infect. Microbiol. 11 (-) 625229 [2021-03-19; online 2021-03-19]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

The GenTree Platform: growth traits and tree-level environmental data in 12 European forest tree species.

Opgenoorth L, Dauphin B, Benavides R, ..., Aravanopoulos FA, Cavers S

Gigascience 10 (3) - [2021-03-18; online 2021-03-19]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Ca2+-dependent mechanism of membrane insertion and destabilization by the SARS-CoV-2 fusion peptide.

Khelashvili G, Plante A, Doktorova M, Weinstein H

Biophys. J. 120 (6) 1105-1119 [2021-03-16; online 2021-02-23]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

High Expression of LINC01268 is Positively Associated with Hepatocellular Carcinoma Progression via Regulating MAP3K7.

Jin X, Fu W, Li D, ..., Kutter C, Li Y

Onco Targets Ther 14 (-) 1753-1769 [2021-03-08; online 2021-03-08]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Phosphodiesterase 4A confers resistance to PGE2-mediated suppression in CD25+ /CD54+ NK cells.

Chen Z, Yang Y, Neo SY, ..., Sarhan D, Lundqvist A

EMBO Rep. 22 (3) e51329 [2021-03-03; online 2021-01-22]

SciLifeLab Fellow Yumeng Mao

DOI Crossref

ZFP207 controls pluripotency by multiple post-transcriptional mechanisms

Malla S, Bhattarai DP, Melguizo-Sanchis D, ..., Kutter C, Aguilo F

- - (-) - [2021-03-02; online 2021-03-02]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Ulipristal Acetate for Treatment of Premenstrual Dysphoric Disorder: A Proof-of-Concept Randomized Controlled Trial.

Comasco E, Kopp Kallner H, Bixo M, ..., Epperson CN, Sundström-Poromaa I

Am J Psychiatry 178 (3) 256-265 [2021-03-01; online 2020-12-10]

Erika Comasco SciLifeLab Fellow

DOI Crossref

The GenTree Leaf Collection: Inter‐ and intraspecific leaf variation in seven forest tree species in Europe

Benavides R, Carvalho B, Bastias CC, ..., Fady B, Valladares F

Global Ecol. Biogeogr. 30 (3) 590-597 [2021-03-00; online 2021-01-06]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson’s disease

Rosario D, Bidkhori G, Lee S, ..., Mardinoglu A, Shoaie S

Cell Reports 34 (9) 108807 [2021-03-00; online 2021-03-00]

Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

No evidence for a placental microbiome in human pregnancies at term.

Sterpu I, Fransson E, Hugerth LW, ..., Wiberg-Itzel E, Schuppe-Koistinen I

Am J Obstet Gynecol 224 (3) 296.e1-296.e23 [2021-03-00; online 2020-08-29]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

Bick AG, Weinstock JS, Nandakumar SK, ..., Kathiresan S, Natarajan P

Nature 591 (7851) E27 [2021-03-00; online 2021-03-13]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

3D-printing of solid lipid tablets from emulsion gels

Johannesson J, Khan J, Hubert M, Teleki A, Bergström CAS

Int J Pharm 597 (-) 120304 [2021-03-00; online 2021-03-00]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

Antibiotic Resistance in Shiga Toxigenic Escherichia coli Isolates from Surface Waters and Sediments in a Mixed Use Urban Agricultural Landscape.

Ma Y, Chen J, Fong K, ..., Delaquis P, Wang S

Antibiotics (Basel) 10 (3) - [2021-02-26; online 2021-02-26]

DDLS Fellow Laura Carroll

DOI Crossref

The Organelle in the Ointment: cryptic mitochondria account for many unknown sequences in cross-species microbiome comparisons

Sonett D, Brown T, Bengtsson-Palme J, Padilla-Gamiño JL, Zaneveld JR

bioRxiv preprint - (-) - [2021-02-24; online 2021-02-24]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Accelerating target deconvolution for therapeutic antibody candidates using highly parallelized genome editing.

Mattsson J, Ekdahl L, Junghus F, ..., Teige I, Nilsson B

Nat Commun 12 (1) 1277 [2021-02-24; online 2021-02-24]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Spatial Regulation of T-Cell Signaling by Programmed Death-Ligand 1 on Wireframe DNA Origami Flat Sheets.

Fang T, Alvelid J, Spratt J, ..., Testa I, Teixeira AI

ACS Nano 15 (2) 3441-3452 [2021-02-23; online 2021-02-08]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Chenodeoxycholic Acid Modulates Bile Acid Synthesis Independent of Fibroblast Growth Factor 19 in Primary Human Hepatocytes.

Johansson H, Søndergaard JN, Jorns C, Kutter C, Ellis ECS

Front Endocrinol (Lausanne) 11 (-) 554922 [2021-02-22; online 2021-02-22]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Mechanism of membrane-tethered mitochondrial protein synthesis.

Itoh Y, Andréll J, Choi A, ..., Battersby BJ, Amunts A

Science (New York, N.Y.) 371 (6531) 846-849 [2021-02-19; online 2021-02-20]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Continuous human uterine NK cell differentiation in response to endometrial regeneration and pregnancy.

Strunz B, Bister J, Jönsson H, ..., Ivarsson MA, Björkström NK

Sci Immunol 6 (56) - [2021-02-19; online 2021-02-19]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.

Hewitt G, Borel V, Segura-Bayona S, ..., Deindl S, Boulton SJ

Mol. Cell 81 (4) 767-783.e11 [2021-02-18; online 2020-12-16]

SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women.

Honigberg MC, Zekavat SM, Niroula A, ..., NHLBI Trans-Omics for Precision Medicine Program , Natarajan P

Circulation 143 (5) 410-423 [2021-02-02; online 2020-11-09]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Bistability in oxidative stress response determines the migration behavior of phytoplankton in turbulence.

Carrara F, Sengupta A, Behrendt L, Vardi A, Stocker R

Proc. Natl. Acad. Sci. U.S.A. 118 (5) - [2021-02-02; online 2021-01-27]

Lars Behrendt SciLifeLab Fellow

PubMed DOI Crossref

Spatiotemporal dissection of the cell cycle with single-cell proteogenomics.

Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan DP, Lundberg E

Nature 590 (7847) 649-654 [2021-02-00; online 2021-02-24]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1.

Rosestedt M, Velikyan I, Rosenström U, ..., Nordeman P, Eriksson O

Nucl. Med. Biol. 93 (-) 54-62 [2021-02-00; online 2020-11-28]

Olof Eriksson SciLifeLab Fellow

DOI Crossref

Phylogenomics of the tropical plant family Ochnaceae using targeted enrichment of nuclear genes and 250+ taxa

Schneider JV, Jungcurt T, Cardoso D, ..., Berberich T, Zizka G

TAXON 70 (1) 48-71 [2021-02-00; online 2020-12-31]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

Optofluidic Raman-activated cell sorting for targeted genome retrieval or cultivation of microbial cells with specific functions.

Lee KS, Pereira FC, Palatinszky M, ..., Wagner M, Stocker R

Nat Protoc 16 (2) 634-676 [2021-02-00; online 2020-12-11]

Lars Behrendt SciLifeLab Fellow

PubMed DOI Crossref

NGSpeciesID: DNA barcode and amplicon consensus generation from long-read sequencing data.

Sahlin K, Lim MCW, Prost S

Ecol Evol 11 (3) 1392-1398 [2021-02-00; online 2021-01-11]

Kristoffer Sahlin SciLifeLab Fellow

PubMed DOI Crossref

Model membrane systems to reconstitute immune cell signaling.

Céspedes PF, Beckers D, Dustin ML, Sezgin E

FEBS J. 288 (4) 1070-1090 [2021-02-00; online 2020-08-03]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Hybrid seed incompatibility in Capsella is connected to chromatin condensation defects in the endosperm.

Dziasek K, Simon L, Lafon-Placette C, ..., Slotte T, Köhler C

PLoS Genet 17 (2) e1009370 [2021-02-00; online 2021-02-11]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Epithelial inflammasomes in the defense against Salmonella gut infection.

Fattinger SA, Sellin ME, Hardt WD

Curr Opin Microbiol 59 (-) 86-94 [2021-02-00; online 2020-10-28]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Comparison of two arylsulfatases for targeted mass spectrometric analysis of microbiota-derived metabolites

Jain A, Correia MSP, Meistermann H, ..., Löhr JM, Globisch D

J Pharm Biomed Anal 195 (-) 113818 [2021-02-00; online 2021-02-00]

Daniel Globisch SciLifeLab Fellow

DOI Crossref

Character and environmental lability of cyanobacteria‐derived dissolved organic matter

Patriarca C, Sedano‐Núñez VT, Garcia SL, ..., Tranvik LJ, Hawkes JA

Limnol. Oceanogr. 66 (2) 496-509 [2021-02-00; online 2020-10-09]

Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

Acute kidney injury leading to CKD is associated with a persistence of metabolic dysfunction and hypertriglyceridemia

Harzandi A, Lee S, Bidkhori G, ..., Shoaie S, Sharpe CC

iScience 24 (2) 102046 [2021-02-00; online 2021-02-00]

Saeed Shoaie SciLifeLab Fellow

DOI Crossref

iucn_sim : a new program to simulate future extinctions based on IUCN threat status

Andermann T, Faurby S, Cooke R, Silvestro D, Antonelli A

Ecography 44 (2) 162-176 [2021-02-00; online 2020-11-10]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

Epidemiological modeling in StochSS Live!

Jiang R, Jacob B, Geiger M, ..., Hellander A, Petzold L

Bioinformatics - (-) - [2021-01-29; online 2021-01-29]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Identification of ligand-specific G protein-coupled receptor states and prediction of downstream efficacy via data-driven modeling.

Fleetwood O, Carlsson J, Delemotte L

Elife 10 (-) - [2021-01-28; online 2021-01-28]

Jens Carlsson Lucie Delemotte SciLifeLab Fellow

DOI Crossref

Cellocity: A Python package for analysis of confluent cell layer dynamics

Eriksson J, Styrström D, Sellin M

JOSS 6 (57) 2818 [2021-01-28; online 2021-01-28]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers.

Li X, Kim W, Arif M, ..., Zhang C, Mardinoglu A

Cancers (Basel) 13 (2) - [2021-01-19; online 2021-01-19]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Direct detection of SARS-CoV-2 using non-commercial RT-LAMP reagents on heat-inactivated samples.

Alekseenko A, Barrett D, Pareja-Sanchez Y, ..., Yin X, Pelechano V

Sci Rep 11 (1) 1820 [2021-01-19; online 2021-01-19]

SciLifeLab Fellow Simon Elsässer Vicent Pelechano

PubMed DOI Crossref

Single-Molecule, Super-Resolution, and Functional Analysis of G Protein-Coupled Receptor Behavior Within the T Cell Immunological Synapse.

Felce JH, Parolini L, Sezgin E, ..., Frater J, Dustin ML

Front Cell Dev Biol 8 (-) 608484 [2021-01-18; online 2021-01-18]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Nradd Acts as a Negative Feedback Regulator of Wnt/β-Catenin Signaling and Promotes Apoptosis.

Ozalp O, Cark O, Azbazdar Y, ..., Sezgin E, Ozhan G

Biomolecules 11 (1) - [2021-01-14; online 2021-01-14]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids.

Geiser P, Di Martino ML, Samperio Ventayol P, ..., Hellström PM, Sellin ME

MBio 12 (1) - [2021-01-12; online 2021-01-12]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae.

Rodríguez-Galán O, García-Gómez JJ, Rosado IV, ..., Kressler D, de la Cruz J

Nucleic Acids Res. 49 (1) 206-220 [2021-01-11; online 2020-12-18]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Universal and taxon-specific trends in protein sequences as a function of age.

James JE, Willis SM, Nelson PG, ..., Kosinski LJ, Masel J

Elife 10 (-) - [2021-01-08; online 2021-01-08]

DDLS Fellow Jennifer James

PubMed DOI Crossref

Obese mother offspring have hepatic lipidic modulation that contributes to sex-dependent metabolic adaptation later in life.

Savva C, Helguero LA, González-Granillo M, ..., Kutter C, Korach-André M

Commun Biol 4 (1) 14 [2021-01-04; online 2021-01-04]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis.

Sahlin K, Medvedev P

Nat Commun 12 (1) 2 [2021-01-04; online 2021-01-04]

Kristoffer Sahlin SciLifeLab Fellow

PubMed DOI Crossref

CAFE: a software suite for analysis of paired-sample transposon insertion sequencing data.

Abramova A, Osińska A, Kunche H, Burman E, Bengtsson-Palme J

Bioinformatics - (-) - [2021-01-04; online 2021-01-04]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

The effect of Toll-like receptor stimulation on the motility of regulatory T cells.

Chodaczek G, Pagni PP, Christoffersson G, ..., Wegrzyn AS, von Herrath M

J. Autoimmun. 116 (-) 102563 [2021-01-00; online 2020-11-12]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Systems biology based drug repositioning for development of cancer therapy.

Turanli B, Altay O, Borén J, ..., Arga KY, Mardinoglu A

Semin. Cancer Biol. 68 (-) 47-58 [2021-01-00; online 2019-09-27]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease.

Asad S, Wegler C, Ahl D, ..., Artursson P, Teleki A

J Pharm Sci 110 (1) 239-250 [2021-01-00; online 2020-11-04]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

News ways of understanding the complex biology of diabetes using PET.

Eriksson O, Långström B, Antoni G

Nucl. Med. Biol. 92 (-) 65-71 [2021-01-00; online 2020-04-27]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Neuroimaging the menstrual cycle: A multimodal systematic review.

Dubol M, Epperson CN, Sacher J, ..., Sundström-Poromaa I, Comasco E

Front Neuroendocrinol 60 (-) 100878 [2021-01-00; online 2020-10-22]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality.

Stebbing J, Sánchez Nievas G, Falcone M, ..., Abizanda P, Lauschke VM

Sci Adv 7 (1) - [2021-01-00; online 2021-01-01]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Ligand design by targeting a binding site water

Matricon P, Suresh RR, Gao ZG, ..., Jacobson KA, Carlsson J

Chem Sci 12 (3) 960-968 [2021-00-00; online 2021-00-00]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Investigation of the individual human sulfatome in plasma and urine samples reveals an age-dependency

Correia MSP, Thapa B, Vujasinovic M, Löhr JM, Globisch D

RSC Adv. 11 (55) 34788-34794 [2021-00-00; online 2021-00-00]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

5´XP sRNA-seq: efficient identification of transcripts with and without 5´ phosphorylation reveals evolutionary conserved small RNA.

Kugelberg U, Nätt D, Skog S, Kutter C, Öst A

RNA Biol - (-) 1-12 [2020-12-31; online 2020-12-31]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Development and external validation of a COVID-19 mortality risk prediction algorithm: a multicentre retrospective cohort study.

Mei J, Hu W, Chen Q, ..., Yue J, Wang QL

BMJ Open 10 (12) e044028 [2020-12-24; online 2020-12-24]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.

Lehmann LC, Bacic L, Hewitt G, ..., Boulton SJ, Deindl S

Cell Reports 33 (12) 108529 [2020-12-22; online 2020-12-29]

SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Ileocolonic Histopathological and Microbial Alterations in the Irritable Bowel Syndrome: A Nested Community Case-Control Study.

Talley NJ, Alexander JL, Walker MM, ..., Powell N, Andreasson A

Clin Transl Gastroenterol 12 (1) e00296 [2020-12-22; online 2020-12-22]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Ancient microRNA profiles of a 14,300-year-old canid samples confirm taxonomic origin and give glimpses into tissue-specific gene regulation from the Pleistocene.

Fromm B, Tarbier M, Smith O, ..., Gilbert TP, Friedlander MR

RNA - (-) - [2020-12-15; online 2020-12-15]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Automated Removal of Non-homologous Sequence Stretches with PREQUAL.

Irisarri I, Burki F, Whelan S

Methods in molecular biology (Clifton, N.J.) 2231 (-) 147-162 [2020-12-09; online 2020-12-09]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development.

Malkani S, Chin CR, Cekanaviciute E, ..., Mason CE, Beheshti A

Cell Reports 33 (10) 108448 [2020-12-08; online 2020-11-25]

DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow

PubMed DOI Crossref

Mitochondrial DNA Sequence Diversity in Mammals: A Correlation between the Effective and Census Population Sizes.

James J, Eyre-Walker A

Genome Biol Evol 12 (12) 2441-2449 [2020-12-06; online 2020-10-24]

DDLS Fellow Jennifer James

PubMed DOI Crossref

Microbial model communities: To understand complexity, harness the power of simplicity.

Bengtsson-Palme J

Comput Struct Biotechnol J 18 (-) 3987-4001 [2020-12-02; online 2020-12-02]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Structural and functional consequences of reversible lipid asymmetry in living membranes.

Doktorova M, Symons JL, Levental I

Nat. Chem. Biol. 16 (12) 1321-1330 [2020-12-00; online 2020-11-16]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

S100A6 is a critical regulator of hematopoietic stem cells.

Grahn THM, Niroula A, Végvári Á, ..., Zubarev RA, Karlsson S

Leukemia 34 (12) 3323-3337 [2020-12-00; online 2020-06-19]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Recent advances in single-molecule fluorescence microscopy render structural biology dynamic

Bacic L, Sabantsev A, Deindl S

Current Opinion in Structural Biology 65 (-) 61-68 [2020-12-00; online 2020-12-00]

SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Identification of areas of grading difficulties in prostate cancer and comparison with artificial intelligence assisted grading.

Egevad L, Swanberg D, Delahunt B, ..., Clements M, Eklund M

Virchows Arch. 477 (6) 777-786 [2020-12-00; online 2020-06-15]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Genome-wide detection of DNA double-strand breaks by in-suspension BLISS.

Bouwman BAM, Agostini F, Garnerone S, ..., Roukos V, Crosetto N

Nat Protoc 15 (12) 3894-3941 [2020-12-00; online 2020-11-02]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Distinct pre-initiation steps in human mitochondrial translation

Khawaja A, Itoh Y, Remes C, ..., Amunts A, Rorbach J

Nat Commun 11 (1) - [2020-12-00; online 2020-06-10]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Colonization factor CS30 from enterotoxigenic Escherichia coli binds to sulfatide in human and porcine small intestine.

Von Mentzer A, Zalem D, Chrienova Z, Teneberg S

Virulence 11 (1) 381-390 [2020-12-00; online 2020-04-05]

Astrid von Mentzer DDLS Fellow

PubMed DOI Crossref

Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening.

Kang PW, Westerlund AM, Shi J, ..., Delemotte L, Cui J

Sci Adv 6 (50) - [2020-12-00; online 2020-12-11]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi

Itoh Y, Naschberger A, Mortezaei N, Herrmann JM, Amunts A

Nat Commun 11 (1) - [2020-12-00; online 2020-10-14]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Universal Single-Residue Terminal Labels for Fluorescent Live Cell Imaging of Microproteins.

Lafranchi L, Schlesinger D, Kimler KJ, Elsässer SJ

Journal of the American Chemical Society 142 (47) 20080-20087 [2020-11-25; online 2020-11-11]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Improved computational analysis of ribosome dynamics from 5′P degradome data using fivepseq

Nersisyan L, Ropat M, Pelechano V

NAR Genomics and Bioinformatics 2 (4) - [2020-11-24; online 2020-11-24]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Comparative interactomes of HSF1 in stress and disease reveal a role for CTCF in HSF1-mediated gene regulation.

Burchfiel ET, Vihervaara A, Guertin MJ, Gomez-Pastor R, Thiele DJ

J Biol Chem 296 (-) 100097 [2020-11-24; online 2020-11-24]

Anniina Vihervaara SciLifeLab Fellow

PubMed DOI Crossref

Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells.

Zhan C, Bidkhori G, Schwarz H, ..., Rockberg J, Chotteau V

iScience 23 (11) 101653 [2020-11-20; online 2020-10-07]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Comparative dietary sulfated metabolome analysis reveals unknown metabolic interactions of the gut microbiome and the human host.

Correia MSP, Jain A, Alotaibi W, ..., Rodriguez-Mateos A, Globisch D

Free Radic. Biol. Med. 160 (-) 745-754 [2020-11-20; online 2020-09-11]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Amino Acid Modified RNA Bases as Building Blocks of an Early Earth RNA-Peptide World.

Nainytė M, Müller F, Ganazzoli G, ..., Globisch D, Carell T

Chemistry 26 (65) 14856-14860 [2020-11-20; online 2020-10-14]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Assessment of In Vitro and In Silico Protocols for Sequence-Based Characterization of the Human Vaginal Microbiome.

Hugerth LW, Pereira M, Zha Y, ..., Schuppe-Koistinen I, Engstrand L

mSphere 5 (6) - [2020-11-18; online 2020-11-18]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Lipoprotein Particles Interact with Membranes and Transfer Their Cargo without Receptors

Plochberger B, Sych T, Weber F, ..., Stangl H, Sezgin E

Biochemistry 59 (45) 4421-4428 [2020-11-17; online 2020-11-04]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19.

Consiglio CR, Cotugno N, Sardh F, ..., Palma P, Brodin P

Cell 183 (4) 968-981.e7 [2020-11-12; online 2020-09-06]

Camila Consiglio DDLS Fellow

PubMed DOI Crossref

DNA methylation in infants with low and high body fatness.

Henriksson P, Lentini A, Altmäe S, ..., Nestor CE, Löf M

BMC Genomics 21 (1) 769 [2020-11-09; online 2020-11-09]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

Genomic Characterization of Salmonella Minnesota Clonal Lineages Associated with Poultry Production in Brazil.

Kipper D, Carroll LM, Mascitti AK, ..., Ikuta N, Lunge VR

Animals (Basel) 10 (11) - [2020-11-05; online 2020-11-05]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Novel Effective Bacillus cereus Group Species "Bacillus clarus" Is Represented by Antibiotic-Producing Strain ATCC 21929 Isolated from Soil.

Méndez Acevedo M, Carroll LM, Mukherjee M, ..., Dudley EG, Kovac J

mSphere 5 (6) - [2020-11-04; online 2020-11-04]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Redesigning Solvatochromic Probe Laurdan for Imaging Lipid Order Selectively in Cell Plasma Membranes.

Danylchuk DI, Sezgin E, Chabert P, Klymchenko AS

Anal. Chem. 92 (21) 14798-14805 [2020-11-03; online 2020-10-12]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Computational Analysis of Alzheimer Amyloid Plaque Composition in 2D- and Elastically Reconstructed 3D-MALDI MS Images.

Enzlein T, Cordes J, Munteanu B, ..., Chávez-Gutiérrez L, Hopf C

Anal. Chem. 92 (21) 14484-14493 [2020-11-03; online 2020-10-14]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Tracking the motion of the KV 1.2 voltage sensor reveals the molecular perturbations caused by a de novo mutation in a case of epilepsy.

Pantazis A, Kaneko M, Angelini M, ..., Saitta SC, Olcese R

J. Physiol. (Lond.) 598 (22) 5245-5269 [2020-11-00; online 2020-09-21]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Quantification of aromatase binding in the female human brain using [11 C]cetrozole positron emission tomography.

Jonasson M, Nordeman P, Eriksson J, ..., Lubberink M, Comasco E

J Neurosci Res 98 (11) 2208-2218 [2020-11-00; online 2020-08-06]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) induce epigenetic alterations and promote human breast cell carcinogenesis in vitro.

Pierozan P, Cattani D, Karlsson O

Arch. Toxicol. 94 (11) 3893-3906 [2020-11-00; online 2020-07-22]

Oskar Karlsson SciLifeLab Fellow

DOI Crossref

Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F

Oosterheert W, Xenaki KT, Neviani V, ..., van Bergen en Henegouwen PM, Gros P

Life Sci. Alliance 3 (11) e202000883 [2020-11-00; online 2020-09-21]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

Differences in structure and hibernation mechanism highlight diversification of the microsporidian ribosome

Ehrenbolger K, Jespersen N, Sharma H, ..., Vossbrinck CR, Barandun J

PLoS Biol. 18 (10) e3000958 [2020-10-30; online 2020-10-30]

Jonas Barandun SciLifeLab Fellow

PubMed DOI Crossref

Potential Anticancer Effect of Carvacrol Codrugs on Human Glioblastoma Cells.

Yazici A, Marinelli L, Cacciatore I, ..., Mardinoğlu A, Türkez H

Curr Drug Deliv 18 (3) 350-356 [2020-10-29; online 2020-10-29]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Fluidity and Lipid Composition of Membranes of Peroxisomes, Mitochondria and the ER From Oleic Acid-Induced Saccharomyces cerevisiae

Reglinski K, Steinfort-Effelsberg L, Sezgin E, ..., Eggeling C, Erdmann R

Front Cell Dev Biol 8 (-) 574363 [2020-10-29; online 2020-10-29]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells.

Tarbier M, Mackowiak SD, Frade J, ..., Gallant CJ, Friedländer MR

Nat Commun 11 (1) 5445 [2020-10-28; online 2020-10-28]

Magda Bienko Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Hippocampal neural stem cells are more susceptible to the neurotoxin BMAA than primary neurons: effects on apoptosis, cellular differentiation, neurite outgrowth, and DNA methylation.

Pierozan P, Cattani D, Karlsson O

Cell Death Dis 11 (10) 910 [2020-10-24; online 2020-10-24]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization.

Flygaard RK, Mühleip A, Tobiasson V, Amunts A

Nat Commun 11 (1) 5342 [2020-10-22; online 2020-10-22]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Rapid Preparation of a Large Sulfated Metabolite Library for Structure Validation in Human Samples.

Correia MSP, Lin W, Aria AJ, Jain A, Globisch D

Metabolites 10 (10) 415 [2020-10-16; online 2020-10-16]

Daniel Globisch SciLifeLab Fellow

PubMed

[11C]5-Hydroxy-tryptophan model for quantitative assessment of in vivo serotonin biosynthesis, retention and degradation in the endocrine pancreas.

Lubberink M, Eriksson O

American journal of nuclear medicine and molecular imaging 10 (5) 226-234 [2020-10-15; online 2020-10-15]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Androgen Receptor Signaling Positively Regulates Monocytic Development.

Consiglio CR, Gollnick SO

Front Immunol 11 (-) 519383 [2020-10-15; online 2020-10-15]

Camila Consiglio DDLS Fellow

PubMed DOI Crossref

Network analysis reveals how lipids and other cofactors influence membrane protein allostery.

Westerlund AM, Fleetwood O, Pérez-Conesa S, Delemotte L

J Chem Phys 153 (14) 141103 [2020-10-14; online 2020-10-23]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

TIF-Seq2 disentangles overlapping isoforms in complex human transcriptomes.

Wang J, Li B, Marques S, ..., Wei W, Pelechano V

Nucleic Acids Res. 48 (18) e104 [2020-10-09; online 2020-08-21]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility.

Navarro C, Lyu J, Katsori AM, Caridha R, Elsässer SJ

Nat Commun 11 (1) 5095 [2020-10-09; online 2020-10-09]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes.

Eriksson O, Haack T, Hijazi Y, ..., Wagner M, Tillner J

Sci Rep 10 (1) 16758 [2020-10-07; online 2020-10-07]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

HEARTBREAK Controls Post-translational Modification of INDEHISCENT to Regulate Fruit Morphology in Capsella.

Dong Y, Majda M, Šimura J, ..., Smith RS, Østergaard L

Curr. Biol. 30 (19) 3880-3888.e5 [2020-10-05; online 2020-08-13]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Progesterone - Friend or foe?

Sundström-Poromaa I, Comasco E, Sumner R, Luders E

Front Neuroendocrinol 59 (-) 100856 [2020-10-00; online 2020-07-28]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Male swarming aggregation pheromones increase female attraction and mating success among multiple African malaria vector mosquito species.

Mozūraitis R, Hajkazemian M, Zawada JW, ..., Borg-Karlson AK, Emami SN

Nat Ecol Evol 4 (10) 1395-1401 [2020-10-00; online 2020-08-03]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

GPSeq reveals the radial organization of chromatin in the cell nucleus.

Girelli G, Custodio J, Kallas T, ..., Crosetto N, Bienko M

Nat. Biotechnol. 38 (10) 1184-1193 [2020-10-00; online 2020-05-25]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Body composition after allogeneic haematopoietic cell transplantation/total body irradiation in children and young people: a restricted systematic review.

Lorenc A, Hamilton-Shield J, Perry R, Stevens M, CTYA HSCT Adipose and Muscle Late Effects Working Group

J Cancer Surviv 14 (5) 624-642 [2020-10-00; online 2020-07-18]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

ANHIR: Automatic Non-Rigid Histological Image Registration Challenge.

Borovec J, Kybic J, Arganda-Carreras I, ..., Zhao S, Munoz-Barrutia A

IEEE Trans Med Imaging 39 (10) 3042-3052 [2020-10-00; online 2020-04-07]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Streamlined and Abundant Bacterioplankton Thrive in Functional Cohorts.

Mondav R, Bertilsson S, Buck M, ..., Lindström ES, Garcia SL

mSystems 5 (5) - [2020-09-29; online 2020-09-29]

Sarahi Garcia SciLifeLab Fellow

DOI Crossref

Effect of molecular phenotype based on Warburg effect pathway on the prognosis and the efficacy of postoperative radiation in cervical cancer

Li N, Xu H, Sun X, ..., Zhou Y, Zhou F

Chinese Journal of Radiological Medicine and Protection 40 (9) 666-673 [2020-09-25]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase.

Degorce SL, Tavana O, Banks E, ..., Yang B, Edmondson SD

J Med Chem 63 (18) 10460-10473 [2020-09-24; online 2020-09-14]

SciLifeLab Fellow Yumeng Mao

PubMed DOI Crossref

Massive and rapid COVID-19 testing is feasible by extraction-free SARS-CoV-2 RT-PCR.

Smyrlaki I, Ekman M, Lentini A, ..., Högberg B, Reinius B

Nat Commun 11 (1) 4812 [2020-09-23; online 2020-09-23]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

No Assembly Required: Using BTyper3 to Assess the Congruency of a Proposed Taxonomic Framework for the Bacillus cereus Group With Historical Typing Methods.

Carroll LM, Cheng RA, Kovac J

Front Microbiol 11 (-) 580691 [2020-09-22; online 2020-09-22]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning.

Mohammadi E, Benfeitas R, Turkez H, ..., Uhlen M, Mardinoglu A

Cancers (Basel) 12 (9) - [2020-09-21; online 2020-09-21]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Compositional and functional differences of the mucosal microbiota along the intestine of healthy individuals.

Vaga S, Lee S, Ji B, ..., Engstrand L, Shoaie S

Sci Rep 10 (1) 14977 [2020-09-11; online 2020-09-11]

Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

Disease, Drugs and Dysbiosis: Understanding Microbial Signatures in Metabolic Disease and Medical Interventions.

Proffitt C, Bidkhori G, Moyes D, Shoaie S

Microorganisms 8 (9) 1381 [2020-09-09; online 2020-09-09]

Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

Integration of molecular profiles in a longitudinal wellness profiling cohort.

Tebani A, Gummesson A, Zhong W, ..., Uhlen M, Fagerberg L

Nat Commun 11 (1) 4487 [2020-09-08; online 2020-09-08]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

How cholesterol stiffens unsaturated lipid membranes.

Chakraborty S, Doktorova M, Molugu TR, ..., Brown MF, Ashkar R

Proc. Natl. Acad. Sci. U.S.A. 117 (36) 21896-21905 [2020-09-08; online 2020-08-25]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

The RNA exosome shapes the expression of key protein-coding genes.

Wu M, Karadoulama E, Lloret-Llinares M, ..., Jensen TH, Sandelin A

Nucleic Acids Res. 48 (15) 8509-8528 [2020-09-04; online 2020-07-28]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Genome sequence of segmented filamentous bacteria present in the human intestine.

Jonsson H, Hugerth LW, Sundh J, Lundin E, Andersson AF

Commun Biol 3 (1) 485 [2020-09-04; online 2020-09-04]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Twentieth-century emergence of antimicrobial resistant human- and bovine-associated Salmonella enterica serotype Typhimurium lineages in New York State.

Carroll LM, Huisman JS, Wiedmann M

Sci Rep 10 (1) 14428 [2020-09-02; online 2020-09-02]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Corrigendum to "Monoamine oxidase A genotype and methylation moderate the association of maltreatment and aggressive behaviour" [Behav. Brain Res. 382 (2020) 112476].

Checknita D, Bendre M, Ekström TJ, ..., Hodgins S, Nilsson KW

Behav. Brain Res. 393 (-) 112721 [2020-09-01; online 2020-06-23]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

The past and future human impact on mammalian diversity.

Andermann T, Faurby S, Turvey ST, Antonelli A, Silvestro D

Sci Adv 6 (36) - [2020-09-00; online 2020-09-04]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

Systems Biology: A Multi-Omics Integration Approach to Metabolism and the Microbiome.

Son JW, Shoaie S, Lee S

Endocrinol Metab (Seoul) 35 (3) 507-514 [2020-09-00; online 2020-09-22]

Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

PhenoChip: A single-cell phenomic platform for high-throughput photophysiological analyses of microalgae.

Behrendt L, Salek MM, Trampe EL, ..., Kühl M, Stocker R

Sci Adv 6 (36) eabb2754 [2020-09-00; online 2020-09-02]

Lars Behrendt SciLifeLab Fellow

PubMed DOI Crossref

Perspectives from Ten Years of Protist Studies by High-Throughput Metabarcoding.

Santoferrara L, Burki F, Filker S, ..., Dunthorn M, McManus GB

J. Eukaryot. Microbiol. 67 (5) 612-622 [2020-09-00; online 2020-07-02]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Enzalutamide, an Androgen Receptor Antagonist, Enhances Myeloid Cell-Mediated Immune Suppression and Tumor Progression.

Consiglio CR, Udartseva O, Ramsey KD, Bush C, Gollnick SO

Cancer Immunol Res 8 (9) 1215-1227 [2020-09-00; online 2020-07-13]

Camila Consiglio DDLS Fellow

PubMed DOI Crossref

Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19.

Rodriguez L, Pekkarinen PT, Lakshmikanth T, ..., Kekäläinen E, Brodin P

Cell Rep Med 1 (5) 100078 [2020-08-25; online 2020-08-05]

Camila Consiglio DDLS Fellow

PubMed DOI Crossref

Cereulide Synthetase Acquisition and Loss Events within the Evolutionary History of Group III Bacillus cereus Sensu Lato Facilitate the Transition between Emetic and Diarrheal Foodborne Pathogens.

Carroll LM, Wiedmann M

MBio 11 (4) - [2020-08-25; online 2020-08-25]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Mapping DNA Methylation in Mammals: The State of the Art.

Lentini A, Nestor CE

Methods in molecular biology (Clifton, N.J.) 2198 (-) 37-50 [2020-08-22; online 2020-08-22]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

Analyzing DNA-Immunoprecipitation Sequencing Data.

Lentini A, Nestor CE

Methods in molecular biology (Clifton, N.J.) 2198 (-) 431-439 [2020-08-22; online 2020-08-22]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

Natural killer cell immunotypes related to COVID-19 disease severity.

Maucourant C, Filipovic I, Ponzetta A, ..., Björkström NK, Karolinska COVID-19 Study Group

Sci Immunol 5 (50) - [2020-08-21; online 2020-08-23]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

Structural basis of mitochondrial translation.

Aibara S, Singh V, Modelska A, Amunts A

Elife 9 (-) - [2020-08-19; online 2020-08-19]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Direct label-free imaging of nanodomains in biomimetic and biological membranes by cryogenic electron microscopy.

Heberle FA, Doktorova M, Scott HL, ..., Waxham MN, Levental I

Proc. Natl. Acad. Sci. U.S.A. 117 (33) 19943-19952 [2020-08-18; online 2020-08-05]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine N-Acetyltransferase NAT2.

Conway LP, Rendo V, Correia MSP, ..., Sjöblom T, Globisch D

Angew. Chem. Int. Ed. Engl. 59 (34) 14342-14346 [2020-08-17; online 2020-07-08]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Drug Repositioning for P-Glycoprotein Mediated Co-Expression Networks in Colorectal Cancer.

Beklen H, Gulfidan G, Arga KY, Mardinoglu A, Turanli B

Front Oncol 10 (-) 1273 [2020-08-13; online 2020-08-13]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Transcriptional mutagenesis dramatically alters genome-wide p53 transactivation landscape.

Liang S, Ezerskyte M, Wang J, Pelechano V, Dreij K

Sci Rep 10 (1) 13513 [2020-08-11; online 2020-08-11]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Super-resolution RESOLFT microscopy of lipid bilayers using a fluorophore-switch dyad.

Frawley AT, Wycisk V, Xiong Y, ..., Eggeling C, Anderson HL

Chem Sci 11 (33) 8955-8960 [2020-08-10; online 2020-08-10]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution.

Björkman A, Johansen SL, Lin L, ..., Bartek J, Schou KB

Genes Dev. 34 (15-16) 1065-1074 [2020-08-01; online 2020-06-19]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

The cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) targets the olfactory bulb region.

Pierozan P, Piras E, Brittebo E, Karlsson O

Arch. Toxicol. 94 (8) 2799-2808 [2020-08-00; online 2020-05-20]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

Predatory colponemids are the sister group to all other alveolates.

Tikhonenkov DV, Strassert JFH, Janouškovec J, ..., Burki F, Keeling PJ

Mol. Phylogenet. Evol. 149 (-) 106839 [2020-08-00; online 2020-04-21]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Neuroprotective effects of boron nitride nanoparticles in the experimental Parkinson's disease model against MPP+ induced apoptosis.

Küçükdoğru R, Türkez H, Arslan ME, ..., Cacciatore I, Di Stefano A

Metab Brain Dis 35 (6) 947-957 [2020-08-00; online 2020-03-25]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Interference with pancreatic sympathetic signaling halts the onset of diabetes in mice.

Christoffersson G, Ratliff SS, von Herrath MG

Sci Adv 6 (35) eabb2878 [2020-08-00; online 2020-08-26]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Human ovarian cancer intrinsic mechanisms regulate lymphocyte activation in response to immune checkpoint blockade.

Natoli M, Bonito N, Robinson JD, Ghaem-Maghami S, Mao Y

Cancer Immunol. Immunother. 69 (8) 1391-1401 [2020-08-00; online 2020-03-21]

SciLifeLab Fellow Yumeng Mao

PubMed DOI Crossref

GPCRmd uncovers the dynamics of the 3D-GPCRome.

Rodríguez-Espigares I, Torrens-Fontanals M, Tiemann JKS, ..., Guixà-González R, Selent J

Nat. Methods 17 (8) 777-787 [2020-08-00; online 2020-07-13]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Apparent stiffness of vimentin intermediate filaments in living cells and its relation with other cytoskeletal polymers.

Smoler M, Coceano G, Testa I, Bruno L, Levi V

Biochim Biophys Acta Mol Cell Res 1867 (8) 118726 [2020-08-00; online 2020-04-19]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

A pan-cancer analysis of the frequency of DNA alterations across cell cycle activity levels.

Lundberg A, Lindström LS, Parker JS, ..., Bergh J, Tobin NP

Oncogene 39 (32) 5430-5440 [2020-08-00; online 2020-06-24]

Arian Lundberg DDLS Fellow

PubMed DOI Crossref

Automated GMP-Compliant Production of [68Ga]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans.

Wagner M, Doverfjord JG, Tillner J, ..., Eriksson O, Velikyan I

Pharmaceuticals (Basel, Switzerland) 13 (8) 176 [2020-07-31; online 2020-07-31]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Current Status of COVID-19 Therapies and Drug Repositioning Applications.

Altay O, Mohammadi E, Lam S, ..., Uhlen M, Mardinoglu A

iScience 23 (7) 101303 [2020-07-24; online 2020-06-20]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Systems Biology Approaches to Understand the Host-Microbiome Interactions in Neurodegenerative Diseases.

Rosario D, Boren J, Uhlen M, ..., Mardinoglu A, Shoaie S

Front Neurosci 14 (-) 716 [2020-07-08; online 2020-07-08]

Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

Pulsed Electric Fields Can Create Pores in the Voltage Sensors of Voltage-Gated Ion Channels.

Rems L, Kasimova MA, Testa I, Delemotte L

Biophys. J. 119 (1) 190-205 [2020-07-07; online 2020-06-08]

Ilaria Testa Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Rapid Detection of COVID-19 Coronavirus Using a Reverse Transcriptional Loop-Mediated Isothermal Amplification (RT-LAMP) Diagnostic Platform.

Yu L, Wu S, Hao X, ..., Chen WH, Yin X

Clin. Chem. 66 (7) 975-977 [2020-07-01; online 2020-04-22]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Quo vadis microRNAs?

Fromm B, Keller A, Yang X, ..., Peterson KJ, Griffiths-Jones S

Trends in Genetics 36 (7) 461-463 [2020-07-00; online 2020-04-16]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation.

Sieben C, Sezgin E, Eggeling C, Manley S

PLoS Pathog 16 (7) e1008656 [2020-07-00; online 2020-07-08]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

DNA surface exploration and operator bypassing during target search.

Marklund E, van Oosten B, Mao G, ..., Elf J, Deindl S

Nature 583 (7818) 858-861 [2020-07-00; online 2020-06-24]

Daniel Globisch Emil Marklund SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Comparative genomics reveals different population structures associated with host and geographic origin in antimicrobial-resistant Salmonella enterica.

Liao J, Orsi RH, Carroll LM, Wiedmann M

Environ. Microbiol. 22 (7) 2811-2828 [2020-07-00; online 2020-04-27]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

A systems biology approach for studying neurodegenerative diseases.

Lam S, Bayraktar A, Zhang C, ..., Uhlen M, Mardinoglu A

Drug Discov. Today 25 (7) 1146-1159 [2020-07-00; online 2020-05-19]

Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

Molecular Structure of Sphingomyelin in Fluid Phase Bilayers Determined by the Joint Analysis of Small-Angle Neutron and X-ray Scattering Data.

Doktorova M, Kučerka N, Kinnun JJ, ..., Katsaras J, Heberle FA

J Phys Chem B 124 (25) 5186-5200 [2020-06-25; online 2020-06-16]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Skeletal Muscle Transcriptomic Comparison between Long-Term Trained and Untrained Men and Women.

Chapman MA, Arif M, Emanuelsson EB, ..., Mardinoglu A, Sundberg CJ

Cell Reports 31 (12) 107808 [2020-06-23; online 2020-06-25]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Site-Specific Incorporation of Two ncAAs for Two-Color Bioorthogonal Labeling and Crosslinking of Proteins on Live Mammalian Cells.

Meineke B, Heimgärtner J, Eirich J, Landreh M, Elsässer SJ

Cell Reports 31 (12) 107811 [2020-06-23; online 2020-06-25]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Successful delivery of large-size CRISPR/Cas9 vectors in hard-to-transfect human cells using small plasmids.

Søndergaard JN, Geng K, Sommerauer C, ..., Yin X, Kutter C

Commun Biol 3 (1) 319 [2020-06-19; online 2020-06-19]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Adipose tissue morphology, imaging and metabolomics predicting cardiometabolic risk and family history of type 2 diabetes in non-obese men.

Rawshani A, Eliasson B, Rawshani A, ..., Rosengren A, Smith U

Sci Rep 10 (1) 9973 [2020-06-19; online 2020-06-19]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation.

Tobiasson V, Amunts A

Elife 9 (-) e59264 [2020-06-18; online 2020-06-18]

Alexey Amunts SciLifeLab Fellow

DOI Crossref

Chaining with Overlaps Revisited

Sahlin K, Mäkinen V

31st Annual Symposium on Combinatorial Pattern Matching (CPM 2020) 161 (-) 25:1--25:12 [2020-06-09; online 2020-06-09]

Kristoffer Sahlin SciLifeLab Fellow

PubMed DOI Crossref

Sensitive mass spectrometric analysis of carbonyl metabolites in human urine and fecal samples using chemoselective modification.

Lin W, Conway LP, Block A, ..., Löhr JM, Globisch D

Analyst 145 (11) 3822-3831 [2020-06-07; online 2020-05-12]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape.

Lorent JH, Levental KR, Ganesan L, ..., Lyman E, Levental I

Nat. Chem. Biol. 16 (6) 644-652 [2020-06-00; online 2020-05-04]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

No distinct microbiome signature of irritable bowel syndrome found in a Swedish random population.

Hugerth LW, Andreasson A, Talley NJ, ..., Agreus L, Engstrand L

Gut 69 (6) 1076-1084 [2020-06-00; online 2019-10-10]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Improvement in the Current Therapies for Hepatocellular Carcinoma Using a Systems Medicine Approach.

Ozcan M, Altay O, Lam S, ..., Boren J, Mardinoglu A

Adv Biosyst 4 (6) e2000030 [2020-06-00; online 2020-04-08]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Germ-free and microbiota-associated mice yield small intestinal epithelial organoids with equivalent and robust transcriptome/proteome expression phenotypes.

Hausmann A, Russo G, Grossmann J, ..., Sellin ME, Hardt WD

Cell. Microbiol. 22 (6) e13191 [2020-06-00; online 2020-03-04]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Dose and time effects of solar-simulated ultraviolet radiation on the in vivo human skin transcriptome.

Bustamante M, Hernandez-Ferrer C, Tewari A, ..., Nieuwenhuijsen M, Young AR

Br. J. Dermatol. 182 (6) 1458-1468 [2020-06-00; online 2019-11-27]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media.

Teleki A, Nylander O, Bergström CAS

Pharmaceutics 12 (6) 493 [2020-05-28; online 2020-05-28]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

Shift in ecological strategy helps marginal populations of shepherd's purse (Capsella bursa-pastoris) to overcome a high genetic load.

Orsucci M, Milesi P, Hansen J, ..., Glémin S, Lascoux M

Proc. Biol. Sci. 287 (1927) 20200463 [2020-05-27; online 2020-05-20]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis.

Thomas QA, Ard R, Liu J, ..., Pelechano V, Marquardt S

Nat Commun 11 (1) 2589 [2020-05-22; online 2020-05-22]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Integrating the "Immunome" in the Stratification of Myelodysplastic Syndromes and Future Clinical Trial Design.

Winter S, Shoaie S, Kordasti S, Platzbecker U

J Clin Oncol 38 (15) 1723-1735 [2020-05-20; online 2020-02-14]

Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

z-STED Imaging and Spectroscopy to Investigate Nanoscale Membrane Structure and Dynamics.

Barbotin A, Urbančič I, Galiani S, ..., Booth M, Sezgin E

Biophys. J. 118 (10) 2448-2457 [2020-05-19; online 2020-04-16]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis.

Nilsson A, Haanstra JR, Engqvist M, ..., Teusink B, Nielsen J

Proc. Natl. Acad. Sci. U.S.A. 117 (19) 10294-10304 [2020-05-12; online 2020-04-27]

Avlant Nilsson DDLS Fellow

PubMed DOI Crossref

Histidyl-Proline Diketopiperazine Isomers as Multipotent Anti-Alzheimer Drug Candidates.

Turkez H, Cacciatore I, Arslan ME, ..., Di Stefano A, Mardinoglu A

Biomolecules 10 (5) 737 [2020-05-09; online 2020-05-09]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Predicting resolution and image quality in RESOLFT and other point scanning microscopes [Invited].

Bodén A, Casas Moreno X, Cooper BK, York AG, Testa I

Biomed Opt Express 11 (5) 2313-2327 [2020-05-01; online 2020-04-02]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Differential Expression of Immune Genes between Two Closely Related Beetle Species with Different Immunocompetence following Attack by Asecodes parviclava.

Yang X, Fors L, Slotte T, ..., Wheat CW, Hambäck PA

Genome Biol Evol 12 (5) 522-534 [2020-05-01; online 2020-04-14]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

The utility of artificial intelligence in the assessment of prostate pathology.

Egevad L, Ström P, Kartasalo K, ..., Delahunt B, Eklund M

Histopathology 76 (6) 790-792 [2020-05-00; online 2020-05-14]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium.

Fattinger SA, Böck D, Di Martino ML, ..., Hardt WD, Sellin ME

PLoS Pathog 16 (5) e1008503 [2020-05-00; online 2020-05-04]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression.

Hausmann A, Böck D, Geiser P, ..., Sellin ME, Hardt WD

Mucosal Immunol 13 (3) 530-544 [2020-05-00; online 2020-01-17]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development.

Larsson I, Uhlén M, Zhang C, Mardinoglu A

Front Genet 11 (-) 381 [2020-04-17; online 2020-04-17]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

High photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopy.

Schneider F, Hernandez-Varas P, Christoffer Lagerholm B, ..., Eggeling C, Urbančič I

J. Phys. D: Appl. Phys. 53 (16) 164003 [2020-04-15; online 2020-02-13]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

The European Research Network on Signal Transduction (ERNEST): Toward a Multidimensional Holistic Understanding of G Protein-Coupled Receptor Signaling.

Sommer ME, Selent J, Carlsson J, ..., Waldhoer M, Kolb P

ACS pharmacology & translational science 3 (2) 361-370 [2020-04-10; online 2020-03-31]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

The in vitro cytotoxic, genotoxic, and oxidative damage potentials of the oral artificial sweetener aspartame on cultured human blood cells

Çadirci K, Özdemir Tozlu Ö, Türkez H, Mardinoğlu A

Turk J Med Sci 50 (2) 448-454 [2020-04-09; online 2020-04-09]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Pooled CRISPRi screening of the cyanobacterium Synechocystis sp PCC 6803 for enhanced industrial phenotypes.

Yao L, Shabestary K, Björk SM, ..., Jahn M, Hudson EP

Nat Commun 11 (1) 1666 [2020-04-03; online 2020-04-03]

Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease.

Zhang C, Bjornson E, Arif M, ..., Borén J, Mardinoglu A

Mol Syst Biol 16 (4) e9495 [2020-04-00; online 2020-04-28]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Neuroimaging premenstrual dysphoric disorder: A systematic and critical review.

Dubol M, Epperson CN, Lanzenberger R, Sundström-Poromaa I, Comasco E

Front Neuroendocrinol 57 (-) 100838 [2020-04-00; online 2020-04-05]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Investigation of the demetallation of 10-aryl substituted synthetic chlorins under acidic conditions.

Arkhypchuk AI, Xiong R, Borbas KE

J Inorg Biochem 205 (-) 110979 [2020-04-00; online 2020-01-03]

Ruisheng Xiong SciLifeLab Fellow

PubMed DOI Crossref

De Novo Clustering of Long-Read Transcriptome Data Using a Greedy, Quality Value-Based Algorithm.

Sahlin K, Medvedev P

J. Comput. Biol. 27 (4) 472-484 [2020-04-00; online 2020-03-16]

Kristoffer Sahlin SciLifeLab Fellow

PubMed DOI Crossref

Application of unsupervised learning and process simulation for energy optimization of a WWTP under various weather conditions.

Borzooei S, Miranda GHB, Abolfathi S, ..., Meucci L, Zanetti MC

Water Sci Technol 81 (8) 1541-1551 [2020-04-00; online 2020-07-10]

Gisele Miranda SciLifeLab Fellow

PubMed DOI Crossref

An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models.

Choi MJ, Jung SB, Lee SE, ..., Yi HS, Shong M

Diabetologia 63 (4) 837-852 [2020-04-00; online 2020-01-10]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

An atlas of human metabolism.

Robinson JL, Kocabaş P, Wang H, ..., Uhlén M, Nielsen J

Sci Signal 13 (624) eaaz1482 [2020-03-24; online 2020-03-24]

Adil Mardinoglu Avlant Nilsson SciLifeLab Fellow

PubMed DOI Crossref

Monoamine oxidase A genotype and methylation moderate the association of maltreatment and aggressive behaviour.

Checknita D, Bendre M, Ekström TJ, ..., Hodgins S, Nilsson KW

Behav. Brain Res. 382 (-) 112476 [2020-03-16; online 2020-01-10]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Identification of germline variants in adults with hemophagocytic lymphohistiocytosis.

Miller PG, Niroula A, Ceremsak JJ, ..., Berliner N, Ebert BL

Blood Adv 4 (5) 925-929 [2020-03-10; online 2020-03-10]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

An atlas of the protein-coding genes in the human, pig, and mouse brain.

Sjöstedt E, Zhong W, Fagerberg L, ..., Uhlén M, Mulder J

Science (New York, N.Y.) 367 (6482) eaay5947 [2020-03-06; online 2020-03-07]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Stressful Beginnings with Long-Term Consequences.

Consiglio CR, Brodin P

Cell 180 (5) 820-821 [2020-03-05; online 2020-03-07]

Camila Consiglio DDLS Fellow

PubMed DOI Crossref

Membrane lipids are both the substrates and a mechanistically responsive environment of TMEM16 scramblase proteins.

Khelashvili G, Cheng X, Falzone ME, ..., Accardi A, Weinstein H

J Comput Chem 41 (6) 538-551 [2020-03-05; online 2019-11-21]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Structure of a minimal photosystem I from the green alga Dunaliella salina.

Perez-Boerema A, Klaiman D, Caspy I, ..., Amunts A, Nelson N

Nat Plants 6 (3) 321-327 [2020-03-00; online 2020-03-02]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Performance of virtual screening against GPCR homology models: Impact of template selection and treatment of binding site plasticity.

Jaiteh M, Rodríguez-Espigares I, Selent J, Carlsson J

PLoS Comput Biol 16 (3) e1007680 [2020-03-00; online 2020-03-13]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

No evidence for DNA N 6-methyladenine in mammals.

Douvlataniotis K, Bensberg M, Lentini A, Gylemo B, Nestor CE

Sci Adv 6 (12) eaay3335 [2020-03-00; online 2020-03-18]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

MEMOTE for standardized genome-scale metabolic model testing.

Lieven C, Beber ME, Olivier BG, ..., Zakhartsev M, Zhang C

Nat. Biotechnol. 38 (3) 272-276 [2020-03-00; online 2020-03-04]

Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

Long-read metabarcoding of the eukaryotic rDNA operon to phylogenetically and taxonomically resolve environmental diversity.

Jamy M, Foster R, Barbera P, ..., Bass D, Burki F

Mol Ecol Resour 20 (2) 429-443 [2020-03-00; online 2019-11-29]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Life in the dark: far-red absorbing cyanobacteria extend photic zones deep into terrestrial caves.

Behrendt L, Trampe EL, Nord NB, ..., Hershey OS, Barton H

Environ. Microbiol. 22 (3) 952-963 [2020-03-00; online 2019-09-09]

Lars Behrendt SciLifeLab Fellow

PubMed DOI Crossref

Distinct structural modulation of photosystem I and lipid environment stabilizes its tetrameric assembly.

Chen M, Perez-Boerema A, Zhang L, ..., Li S, Amunts A

Nat Plants 6 (3) 314-320 [2020-03-00; online 2020-03-09]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Chemical imaging of evolving amyloid plaque pathology and associated Aβ peptide aggregation in a transgenic mouse model of Alzheimer's disease.

Michno W, Wehrli P, Meier SR, ..., Blennow K, Hanrieder J

J. Neurochem. 152 (5) 602-616 [2020-03-00; online 2019-11-06]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Impact of Nanoscale Hindrances on the Relationship between Lipid Packing and Diffusion in Model Membranes.

Beckers D, Urbancic D, Sezgin E

J Phys Chem B 124 (8) 1487-1494 [2020-02-27; online 2020-02-18]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma.

Das Mahapatra K, Pasquali L, Søndergaard JN, ..., Kristensen LS, Pivarcsi A

Sci Rep 10 (1) 3637 [2020-02-27; online 2020-02-27]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Proposal of a Taxonomic Nomenclature for the Bacillus cereus Group Which Reconciles Genomic Definitions of Bacterial Species with Clinical and Industrial Phenotypes.

Carroll LM, Wiedmann M, Kovac J

MBio 11 (1) - [2020-02-25; online 2020-02-25]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Energy Landscapes Reveal Agonist Control of G Protein-Coupled Receptor Activation via Microswitches.

Fleetwood O, Matricon P, Carlsson J, Delemotte L

Biochemistry 59 (7) 880-891 [2020-02-25; online 2020-02-07]

Jens Carlsson Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

A Guide to Carrying Out a Phylogenomic Target Sequence Capture Project.

Andermann T, Torres Jiménez MF, Matos-Maraví P, ..., Bacon CD, Antonelli A

Front Genet 10 (-) 1407 [2020-02-21; online 2020-02-21]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

Creating Supported Plasma Membrane Bilayers Using Acoustic Pressure.

Sezgin E, Carugo D, Levental I, Stride E, Eggeling C

Membranes (Basel) 10 (2) 30 [2020-02-18; online 2020-02-18]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Biophysical Characterization of Epigallocatechin-3-Gallate Effect on the Cardiac Sodium Channel Nav1.5.

Amarouch MY, Kurt H, Delemotte L, Abriel H

Molecules 25 (4) 902 [2020-02-18; online 2020-02-18]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Radial Organization in the Mammalian Nucleus.

Crosetto N, Bienko M

Front Genet 11 (-) 33 [2020-02-12; online 2020-02-12]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Regulation of lipid saturation without sensing membrane fluidity.

Ballweg S, Sezgin E, Doktorova M, ..., Hummer G, Ernst R

Nat Commun 11 (1) 756 [2020-02-06; online 2020-02-06]

DDLS Fellow Erdinc Sezgin Milka Doktorova SciLifeLab Fellow

PubMed DOI Crossref

Molecular Insights from Conformational Ensembles via Machine Learning.

Fleetwood O, Kasimova MA, Westerlund AM, Delemotte L

Biophys. J. 118 (3) 765-780 [2020-02-04; online 2019-12-21]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Abundance and diversity of resistomes differ between healthy human oral cavities and gut.

Carr VR, Witherden EA, Lee S, ..., Gomez-Cabrero D, Moyes DL

Nat Commun 11 (1) 693 [2020-02-04; online 2020-02-04]

Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API.

Desvignes T, Loher P, Eilbeck K, ..., Halushka MK, Pantano L

Bioinformatics 36 (3) 698-703 [2020-02-01; online 2019-09-11]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

The molecular basis for sugar import in malaria parasites.

Qureshi AA, Suades A, Matsuoka R, ..., Delemotte L, Drew D

Nature 578 (7794) 321-325 [2020-02-00; online 2020-01-29]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Selective sweeps on novel and introgressed variation shape mimicry loci in a butterfly adaptive radiation.

Moest M, Van Belleghem SM, James JE, ..., Steiner FM, Jiggins CD

PLoS Biol. 18 (2) e3000597 [2020-02-00; online 2020-02-06]

DDLS Fellow Jennifer James

PubMed DOI Crossref

Is evolution predictable? Quantitative genetics under complex genotype-phenotype maps.

Milocco L, Salazar-Ciudad I

Evolution 74 (2) 230-244 [2020-02-00; online 2020-01-03]

DDLS Fellow Lisandro Milocco

PubMed DOI Crossref

Handling ties in continuous outcomes for confounder adjustment with rank-ordered logit and its application to ordinal outcomes.

Ning Y, Tan CS, Maraki A, ..., Reilly M, Støer NC

Stat Methods Med Res 29 (2) 437-454 [2020-02-00; online 2019-04-03]

Erika Comasco SciLifeLab Fellow

DOI Crossref

Environmental impacts and limitations of third‐generation biobutanol: Life cycle assessment of n ‐butanol produced by genetically engineered cyanobacteria

Nilsson A, Shabestary K, Brandão M, Hudson EP

Journal of Industrial Ecology 24 (1) 205-216 [2020-02-00; online 2019-04-00]

Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

Classification of clear cell renal cell carcinoma based on PKM alternative splicing.

Li X, Turanli B, Juszczak K, ..., Zhang C, Mardinoglu A

Heliyon 6 (2) e03440 [2020-02-00; online 2020-02-19]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study.

Ström P, Kartasalo K, Olsson H, ..., Egevad L, Eklund M

Lancet Oncol 21 (2) 222-232 [2020-02-00; online 2020-01-08]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Phylogenomics and biogeography of the world's thrushes (Aves, Turdus): new evidence for a more parsimonious evolutionary history.

Batista R, Olsson U, Andermann T, ..., Ribas CC, Antonelli A

Proc. Biol. Sci. 287 (1919) 20192400 [2020-01-29; online 2020-01-22]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D.

Sayitoglu EC, Georgoudaki AM, Chrobok M, ..., Sutlu T, Duru AD

Front Immunol 11 (-) 40 [2020-01-28; online 2020-01-28]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Population Genomics of Transitions to Selfing in Brassicaceae Model Systems.

Mattila TM, Laenen B, Slotte T

Methods in molecular biology (Clifton, N.J.) 2090 (-) 269-287 [2020-01-25; online 2020-01-25]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Docking Finds GPCR Ligands in Dark Chemical Matter.

Ballante F, Rudling A, Zeifman A, ..., Loza MI, Carlsson J

J Med Chem 63 (2) 613-620 [2020-01-23; online 2020-01-13]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Paenibacillus odorifer, the Predominant Paenibacillus Species Isolated from Milk in the United States, Demonstrates Genetic and Phenotypic Conservation of Psychrotolerance but Clade-Associated Differences in Nitrogen Metabolic Pathways.

Beno SM, Cheng RA, Orsi RH, ..., Martin NH, Wiedmann M

mSphere 5 (1) - [2020-01-22; online 2020-01-22]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

On the Long and Winding Road to a Perfect Membrane Model.

Doktorova M

Biophys. J. 118 (2) 273-275 [2020-01-21; online 2019-11-28]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Evidence of altered mucosa-associated and fecal microbiota composition in patients with Irritable Bowel Syndrome.

Sundin J, Aziz I, Nordlander S, ..., Simrén M, Öhman L

Sci Rep 10 (1) 593 [2020-01-17; online 2020-01-17]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation.

Pagoni A, Marinelli L, Di Stefano A, ..., Vassiliou S, Cacciatore I

Eur J Med Chem 186 (-) 111880 [2020-01-15; online 2019-11-12]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

A set of monomeric near-infrared fluorescent proteins for multicolor imaging across scales.

Matlashov ME, Shcherbakova DM, Alvelid J, ..., Testa I, Verkhusha VV

Nat Commun 11 (1) 239 [2020-01-13; online 2020-01-13]

Ilaria Testa SciLifeLab Fellow

DOI Crossref

Stable stimulated emission depletion imaging of extended sample regions

Alvelid J, Testa I

J. Phys. D: Appl. Phys. 53 (2) 024001 [2020-01-09; online 2019-10-25]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

MirGeneDB 2.0: the metazoan microRNA complement.

Fromm B, Domanska D, Høye E, ..., Friedländer MR, Peterson KJ

Nucleic Acids Res. 48 (D1) D1172 [2020-01-08; online 2019-10-24]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

The GenTree Dendroecological Collection, tree-ring and wood density data from seven tree species across Europe.

Martínez-Sancho E, Slámová L, Morganti S, ..., Westin J, Fonti P

Sci Data 7 (1) 1 [2020-01-02; online 2020-01-02]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Protein aggregation in bacteria.

Schramm FD, Schroeder K, Jonas K

FEMS Microbiol Rev 44 (1) 54-72 [2020-01-01; online 2019-10-22]

Kristina Jonas SciLifeLab Fellow

PubMed DOI Crossref

Advances in GLP-1 receptor targeting radiolabeled agent development and prospective of theranostics.

Velikyan I, Eriksson O

Theranostics 10 (1) 437-461 [2020-01-01; online 2020-01-01]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

The New Tree of Eukaryotes.

Burki F, Roger AJ, Brown MW, Simpson AGB

Trends in Ecology & Evolution 35 (1) 43-55 [2020-01-00; online 2019-10-09]

Fabien Burki SciLifeLab Fellow

DOI Crossref

Ontogenic succession of thermokarst thaw ponds is linked to dissolved organic matter quality and microbial degradation potential

Peura S, Wauthy M, Simone D, ..., Rautio M, Bertilsson S

Limnol. Oceanogr. 65 (S1) - [2020-01-00; online 2020-01-00]

Sari Peura SciLifeLab Fellow

DOI Crossref

Non‐cyanobacterial diazotrophs dominate nitrogen‐fixing communities in permafrost thaw ponds

Fernandez L, Bertilsson S, Peura S

Limnol. Oceanogr. 65 (S1) - [2020-01-00; online 2020-01-00]

Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

Association Between Metformin Use and Risk of Esophageal Squamous Cell Carcinoma in a Population-Based Cohort Study.

Wang QL, Santoni G, Ness-Jensen E, Lagergren J, Xie SH

Am J Gastroenterol 115 (1) 73-78 [2020-01-00; online 2019-12-11]

DDLS Fellow Qiaoli Wang

DOI Crossref

Chapter 7. Bridging the Gap Between Atomistic Molecular Dynamics Simulations and Wet-lab Experimental Techniques: Applications to Membrane Proteins

Delemotte L

- - (-) 247-286 [2020-00-00; online 2020-00-00]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

A genome-wide transcriptomic analysis of protein-coding genes in human blood cells.

Uhlen M, Karlsson MJ, Zhong W, ..., Fagerberg L, Brodin P

Science (New York, N.Y.) 366 (6472) eaax9198 [2019-12-20; online 2019-12-21]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

High genetic diversity but no geographical structure of Aedes albopictus populations in Réunion Island.

Latreille AC, Milesi P, Magalon H, Mavingui P, Atyame CM

Parasit Vectors 12 (1) 597 [2019-12-19; online 2019-12-19]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

MPRAscore: robust and non-parametric analysis of massively parallel reporter assays.

Niroula A, Ajore R, Nilsson B

Bioinformatics 35 (24) 5351-5353 [2019-12-15; online 2019-07-31]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart.

Asp M, Giacomello S, Larsson L, ..., Sylvén C, Lundeberg J

Cell 179 (7) 1647-1660.e19 [2019-12-12; online 2019-12-14]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

InfleCS: Clustering Free Energy Landscapes with Gaussian Mixtures.

Westerlund AM, Delemotte L

J Chem Theory Comput 15 (12) 6752-6759 [2019-12-10; online 2019-11-07]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Overeating Saturated Fat Promotes Fatty Liver and Ceramides Compared With Polyunsaturated Fat: A Randomized Trial.

Rosqvist F, Kullberg J, Ståhlman M, ..., Ahlström H, Risérus U

J. Clin. Endocrinol. Metab. 104 (12) 6207-6219 [2019-12-01; online 2019-08-02]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Nascent RNA analyses: tracking transcription and its regulation.

Wissink EM, Vihervaara A, Tippens ND, Lis JT

Nat. Rev. Genet. 20 (12) 705-723 [2019-12-00; online 2019-08-09]

Anniina Vihervaara SciLifeLab Fellow

DOI Crossref

Fluorescence microscopy at the molecular scale

Alvelid J, Testa I

Current Opinion in Biomedical Engineering 12 (-) 34-42 [2019-12-00; online 2019-12-00]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Enrichment of oral microbiota in early cystic precursors to invasive pancreatic cancer.

Gaiser RA, Halimi A, Alkharaan H, ..., Del Chiaro M, Sällberg Chen M

Gut 68 (12) 2186-2194 [2019-12-00; online 2019-03-14]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.

Wei W, Hennig BP, Wang J, ..., Steinmetz LM, Pelechano V

Genome Res 29 (12) 1974-1984 [2019-12-00; online 2019-11-18]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.

Klevstig M, Arif M, Mannila M, ..., Ehrenborg E, Borén J

J. Mol. Cell. Cardiol. 137 (-) 1-8 [2019-12-00; online 2019-09-15]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Assessing the potential for assisted gene flow using past introduction of Norway spruce in southern Sweden: Local adaptation and genetic basis of quantitative traits in trees.

Milesi P, Berlin M, Chen J, ..., Karlsson B, Lascoux M

Evol Appl 12 (10) 1946-1959 [2019-12-00; online 2019-08-22]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Helix breaking transition in the S4 of HCN channel is critical for hyperpolarization-dependent gating.

Kasimova MA, Tewari D, Cowgill JB, ..., Delemotte L, Chanda B

Elife 8 (-) - [2019-11-27; online 2019-11-27]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

The human secretome.

Uhlén M, Karlsson MJ, Hober A, ..., Fagerberg L, Sivertsson Å

Sci Signal 12 (609) eaaz0274 [2019-11-26; online 2019-11-26]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Evolutionary Refinement of DNA Nanostructures Using Coarse-Grained Molecular Dynamics Simulations.

Benson E, Lolaico M, Tarasov Y, Gådin A, Högberg B

ACS Nano 13 (11) 12591-12598 [2019-11-26; online 2019-10-15]

Erik Benson SciLifeLab Fellow

PubMed DOI Crossref

Effects of sampling strategy and DNA extraction on human skin microbiome investigations.

Bjerre RD, Hugerth LW, Boulund F, ..., Johansen JD, Engstrand L

Sci Rep 9 (1) 17287 [2019-11-21; online 2019-11-21]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Metabolically Active Brown Adipose Tissue Is Found in Adult Subjects with Type 1 Diabetes.

Eriksson O, Selvaraju RK, Berglund M, Espes D

Int J Mol Sci 20 (23) 5827 [2019-11-20; online 2019-11-20]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Structure of a mitochondrial ATP synthase with bound native cardiolipin.

Mühleip A, McComas SE, Amunts A

Elife 8 (-) - [2019-11-18; online 2019-11-18]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

More Favorable Palmitic Acid Over Palmitoleic Acid Modification of Wnt3 Ensures Its Localization and Activity in Plasma Membrane Domains.

Azbazdar Y, Ozalp O, Sezgin E, ..., Karaca E, Ozhan G

Front Cell Dev Biol 7 (-) 281 [2019-11-15; online 2019-11-15]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Complex I is bypassed during high intensity exercise.

Nilsson A, Björnson E, Flockhart M, Larsen FJ, Nielsen J

Nat Commun 10 (1) 5072 [2019-11-07; online 2019-11-07]

Avlant Nilsson DDLS Fellow

PubMed DOI Crossref

ProTstab - predictor for cellular protein stability.

Yang Y, Ding X, Zhu G, ..., Lv Q, Vihinen M

BMC Genomics 20 (1) 804 [2019-11-04; online 2019-11-04]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Systems biology perspective for studying the gut microbiota in human physiology and liver diseases.

Altay O, Nielsen J, Uhlen M, Boren J, Mardinoglu A

EBioMedicine 49 (-) 364-373 [2019-11-00; online 2019-10-18]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Molecular imaging mass spectrometry for probing protein dynamics in neurodegenerative disease pathology.

Michno W, Wehrli PM, Blennow K, Zetterberg H, Hanrieder J

J. Neurochem. 151 (4) 488-506 [2019-11-00; online 2018-11-06]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome.

Barandun J, Hunziker M, Vossbrinck CR, Klinge S

Nat. Microbiol 4 (11) 1798-1804 [2019-11-00; online 2019-07-22]

Jonas Barandun SciLifeLab Fellow

PubMed DOI Crossref

Chemometric Strategies for Sensitive Annotation and Validation of Anatomical Regions of Interest in Complex Imaging Mass Spectrometry Data.

Wehrli PM, Michno W, Blennow K, Zetterberg H, Hanrieder J

J. Am. Soc. Mass Spectrom. 30 (11) 2278-2288 [2019-11-00; online 2019-09-16]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Association of PTHrP levels in CSF with Alzheimer's disease biomarkers.

Kushnir MM, Michno W, Rockwood AL, ..., Strathmann FG, Hanrieder J

Clin Mass Spectrom 14 Pt B (-) 124-129 [2019-11-00; online 2018-10-09]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Sharing Data from Molecular Simulations.

Abraham M, Apostolov R, Barnoud J, ..., Woods C, Zhmurov A

J Chem Inf Model 59 (10) 4093-4099 [2019-10-28; online 2019-10-11]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

The importance of study design in the application of artificial intelligence methods in medicine.

Eklund M, Kartasalo K, Olsson H, Ström P

NPJ Digit Med 2 (-) 101 [2019-10-18; online 2019-10-18]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

CUTseq is a versatile method for preparing multiplexed DNA sequencing libraries from low-input samples.

Zhang X, Garnerone S, Simonetti M, ..., Bienko M, Crosetto N

Nat Commun 10 (1) 4732 [2019-10-18; online 2019-10-18]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates.

Eriksson O, Velikyan I, Haack T, ..., Pierrou S, Wagner M

Sci Rep 9 (1) 14960 [2019-10-18; online 2019-10-18]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Dual Bioorthogonal Labeling of the Amyloid-β Protein Precursor Facilitates Simultaneous Visualization of the Protein and Its Cleavage Products.

van Husen LS, Schedin-Weiss S, Trung MN, ..., Elsässer SJ, Tjernberg LO

J. Alzheimers Dis. 72 (2) 537-548 [2019-10-15; online 2019-10-15]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe.

Cardozo Pinto DF, Yang H, Pollak Dorocic I, ..., Smidt MP, Lammel S

Nat Commun 10 (1) 4633 [2019-10-11; online 2019-10-11]

Iskra Pollak Dorocic SciLifeLab Fellow

PubMed DOI Crossref

Remodeling the genome with DNA twists.

Bowman GD, Deindl S

Science (New York, N.Y.) 366 (6461) 35-36 [2019-10-04; online 2019-10-12]

SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Industrial wastewater treatment plant enriches antibiotic resistance genes and alters the structure of microbial communities.

Bengtsson-Palme J, Milakovic M, Švecová H, ..., Grabic R, Udikovic-Kolic N

Water Res 162 (-) 437-445 [2019-10-01; online 2019-07-04]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

VGLUT2 rs2290045 genotype moderates environmental sensitivity to alcohol-related problems in three samples of youths.

Vrettou M, Nilsson KW, Tuvblad C, ..., Nylander I, Comasco E

Eur Child Adolesc Psychiatry 28 (10) 1329-1340 [2019-10-00; online 2019-02-25]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI.

Espes D, Manell E, Rydén A, ..., Jansson L, Eriksson O

Acta diabetologica 56 (10) 1113-1120 [2019-10-00; online 2019-04-26]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

High-definition spatial transcriptomics for in situ tissue profiling.

Vickovic S, Eraslan G, Salmén F, ..., Regev A, Ståhl PL

Nat. Methods 16 (10) 987-990 [2019-10-00; online 2019-09-09]

Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

Genetic basis and timing of a major mating system shift in Capsella.

Bachmann JA, Tedder A, Laenen B, ..., Castric V, Slotte T

New Phytol. 224 (1) 505-517 [2019-10-00; online 2019-08-01]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Association between Transcription Factor AP-2B genotype, obesity, insulin resistance and dietary intake in a longitudinal birth cohort study.

Joost U, Villa I, Comasco E, ..., Veidebaum T, Harro J

Int J Obes (Lond) 43 (10) 2095-2106 [2019-10-00; online 2019-06-17]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

EvoChromo: towards a synthesis of chromatin biology and evolution.

Drinnenberg IA, Berger F, Elsässer SJ, ..., Warnecke T, Wolfe KH

Development 146 (19) - [2019-09-26; online 2019-09-26]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Cytoplasmic protein misfolding titrates Hsp70 to activate nuclear Hsf1.

Masser AE, Kang W, Roy J, ..., Friedländer MR, Andréasson C

Elife 8 (-) - [2019-09-25; online 2019-09-25]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Chromatin conformation remains stable upon extensive transcriptional changes driven by heat shock.

Ray J, Munn PR, Vihervaara A, ..., Danko CG, Lis JT

Proc. Natl. Acad. Sci. U.S.A. 116 (39) 19431-19439 [2019-09-24; online 2019-09-10]

Anniina Vihervaara SciLifeLab Fellow

PubMed DOI Crossref

What industry can teach academia.

Mao Y

Science (New York, N.Y.) 365 (6459) 1342 [2019-09-20; online 2019-10-12]

SciLifeLab Fellow Yumeng Mao

PubMed DOI Crossref

Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells.

Kumar B, Elsässer SJ

Cell Reports 28 (12) 3274-3284.e5 [2019-09-17; online 2019-09-19]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density.

Steinkühler J, Sezgin E, Urbančič I, Eggeling C, Dimova R

Commun Biol 2 (-) 337 [2019-09-13; online 2019-09-13]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Peptide-Induced Lipid Flip-Flop in Asymmetric Liposomes Measured by Small Angle Neutron Scattering.

Nguyen MHL, DiPasquale M, Rickeard BW, ..., Katsaras J, Marquardt D

Langmuir 35 (36) 11735-11744 [2019-09-10; online 2019-08-27]

DDLS Fellow Milka Doktorova

DOI Crossref

Strategies to Reduce or Eliminate Resistant Pathogens in the Environment

Bengtsson‐Palme J, Heß S

Antibiotic Drug Resistance - (-) 637-673 [2019-09-09; online 2019-08-23]

DDLS Fellow Johan Bengtsson-Palme

DOI Crossref

Mumame: a software tool for quantifying gene-specific point-mutations in shotgun metagenomic data

Magesh S, Jonsson V, Bengtsson-Palme J

MBMG 3 (-) - [2019-09-04; online 2019-09-04]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b.

van den Bos RM, Pearce NM, Granneman J, Brondijk THC, Gros P

Front Immunol 10 (-) 2097 [2019-09-04; online 2019-09-04]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism.

von Beek C, Waern I, Eriksson J, ..., Guss B, Pejler G

Cell. Microbiol. 21 (9) e13064 [2019-09-00; online 2019-07-07]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut.

Bakkeren E, Huisman JS, Fattinger SA, ..., Diard M, Hardt WD

Nature 573 (7773) 276-280 [2019-09-00; online 2019-09-04]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Real-time prediction of influenza outbreaks in Belgium.

Miranda GHB, Baetens JM, Bossuyt N, Bruno OM, De Baets B

Epidemics 28 (-) 100341 [2019-09-00; online 2019-04-18]

Gisele Miranda SciLifeLab Fellow

PubMed DOI Crossref

Investigation of the skin microbiome: swabs vs. biopsies.

Prast-Nielsen S, Tobin AM, Adamzik K, ..., Engstrand L, Fry L

Br. J. Dermatol. 181 (3) 572-579 [2019-09-00; online 2019-05-06]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Impact of demography on linked selection in two outcrossing Brassicaceae species.

Mattila TM, Laenen B, Horvath R, ..., Savolainen O, Slotte T

Ecol Evol 9 (17) 9532-9545 [2019-09-00; online 2019-08-13]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Genomic data provide new insights on the demographic history and the extent of recent material transfers in Norway spruce.

Chen J, Li L, Milesi P, ..., Vendramin GG, Lascoux M

Evol Appl 12 (8) 1539-1551 [2019-09-00; online 2019-04-30]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Early life stress and voluntary alcohol consumption in relation to Maoa methylation in male rats.

Bendre M, Granholm L, Drennan R, ..., Nylander I, Comasco E

Alcohol 79 (-) 7-16 [2019-09-00; online 2018-11-08]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Turning Up the Heat: Local Temperature Control During in vivo Imaging of Immune Cells.

Ahl D, Eriksson O, Sedin J, ..., Christoffersson G, Phillipson M

Front Immunol 10 (-) 2036 [2019-08-27; online 2019-08-27]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Nanoscale dynamics of cholesterol in the cell membrane.

Pinkwart K, Schneider F, Lukoseviciute M, ..., Eggeling C, Sezgin E

J. Biol. Chem. 294 (34) 12599-12609 [2019-08-23; online 2019-07-03]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Molecular Basis and Ecological Relevance of Caulobacter Cell Filamentation in Freshwater Habitats.

Heinrich K, Leslie DJ, Morlock M, Bertilsson S, Jonas K

MBio 10 (4) - [2019-08-20; online 2019-08-20]

Kristina Jonas SciLifeLab Fellow

PubMed DOI Crossref

Progress towards the Tree of Eukaryotes.

Keeling PJ, Burki F

Curr. Biol. 29 (16) R808-R817 [2019-08-19; online 2019-08-21]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

MRPS25 mutations impair mitochondrial translation and cause encephalomyopathy.

Bugiardini E, Mitchell AL, Rosa ID, ..., Pitceathly RDS, Spinazzola A

Hum. Mol. Genet. 28 (16) 2711-2719 [2019-08-15; online 2019-05-01]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer.

Cadenas C, Vosbeck S, Edlund K, ..., Marchan R, Hengstler JG

Int. J. Cancer 145 (4) 901-915 [2019-08-15; online 2019-02-07]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Chemoselective probe for detailed analysis of ketones and aldehydes produced by gut microbiota in human samples.

Conway LP, Garg N, Lin W, ..., Löhr JM, Globisch D

Chem. Commun. (Camb.) 55 (62) 9080-9083 [2019-08-11; online 2019-07-09]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

DiscoverY: a classifier for identifying Y chromosome sequences in male assemblies.

Rangavittal S, Stopa N, Tomaszkiewicz M, ..., Makova KD, Medvedev P

BMC Genomics 20 (1) 641 [2019-08-09; online 2019-08-09]

Kristoffer Sahlin SciLifeLab Fellow

PubMed DOI Crossref

The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5' structure element.

Romilly C, Deindl S, Wagner EGH

Proc. Natl. Acad. Sci. U.S.A. 116 (32) 15901-15906 [2019-08-06; online 2019-07-18]

SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Tools for Bioimaging Pancreatic β Cells in Diabetes.

Kang NY, Soetedjo AAP, Amirruddin NS, ..., Eriksson O, Teo AKK

Trends in molecular medicine 25 (8) 708-722 [2019-08-00; online 2019-06-06]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Strategies for increasing the throughput of super-resolution microscopies.

Mahecic D, Testa I, Griffié J, Manley S

Curr Opin Chem Biol 51 (-) 84-91 [2019-08-00; online 2019-06-15]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Single-cell expression noise and gene-body methylation in Arabidopsis thaliana.

Horvath R, Laenen B, Takuno S, Slotte T

Heredity (Edinb) 123 (2) 81-91 [2019-08-00; online 2019-01-16]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Hypothalamic-pituitary-adrenal axis responsiveness, startle response, and sensorimotor gating in late pregnancy.

Breedh J, Comasco E, Hellgren C, ..., Skalkidou A, Poromaa IS

Psychoneuroendocrinology 106 (-) 1-8 [2019-08-00; online 2019-03-15]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Human prenatal exposure to polychlorinated biphenyls (PCBs) and risk behaviors in adolescence.

Dickerson AS, Ransome Y, Karlsson O

Environ Int 129 (-) 247-255 [2019-08-00; online 2019-05-27]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

Elucidating the Reprograming of Colorectal Cancer Metabolism Using Genome-Scale Metabolic Modeling.

Zhang C, Aldrees M, Arif M, ..., Mardinoglu A, Aziz MA

Front Oncol 9 (-) 681 [2019-07-30; online 2019-07-30]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases.

Gawel DR, Serra-Musach J, Lilja S, ..., Gustafsson M, Benson M

Genome Med 11 (1) 47 [2019-07-30; online 2019-07-30]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

Amyloid fibril polymorphism and cell-specific toxicity in vivo.

Jonson M, Nyström S, Sandberg A, ..., Thor S, Hammarström P

Amyloid 26 (sup1) 136-137 [2019-07-26; online 2019-07-26]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis.

Smillie CS, Biton M, Ordovas-Montanes J, ..., Xavier RJ, Regev A

Cell 178 (3) 714-730.e22 [2019-07-25; online 2019-07-28]

Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

Constitutive Serotonin Transporter Reduction Resembles Maternal Separation with Regard to Stress-Related Gene Expression.

Comasco E, Schijven D, de Maeyer H, ..., Sundström-Poromaa I, Olivier JDA

ACS Chem Neurosci 10 (7) 3132-3142 [2019-07-17; online 2019-01-23]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Assessment of weather-based influent scenarios for a WWTP: Application of a pattern recognition technique.

Borzooei S, Miranda GHB, Teegavarapu R, ..., Meucci L, Zanetti MC

J Environ Manage 242 (-) 450-456 [2019-07-15; online 2019-05-06]

Gisele Miranda SciLifeLab Fellow

PubMed DOI Crossref

The Potential Use of Metabolic Cofactors in Treatment of NAFLD.

Mardinoglu A, Ural D, Zeybel M, ..., Uhlén M, Borén J

Nutrients 11 (7) 1578 [2019-07-12; online 2019-07-12]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.

Nirwan N, Itoh Y, Singh P, ..., Amunts A, Saikrishnan K

Nat Commun 10 (1) 3058 [2019-07-11; online 2019-07-11]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Coupled Enzymatic Treatment and Mass Spectrometric Analysis for Identification of Glucuronidated Metabolites in Human Samples.

Correia MSP, Rao M, Ballet C, Globisch D

Chembiochem 20 (13) 1678-1683 [2019-07-01; online 2019-05-08]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Regulation of the replication initiator DnaA in Caulobacter crescentus.

Felletti M, Omnus DJ, Jonas K

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862 (7) 697-705 [2019-07-00; online 2018-01-31]

Kristina Jonas SciLifeLab Fellow

PubMed DOI Crossref

Plasma Proteomics Analysis Reveals Dysregulation of Complement Proteins and Inflammation in Acquired Obesity-A Study on Rare BMI-Discordant Monozygotic Twin Pairs.

Sahebekhtiari N, Saraswat M, Joenväärä S, ..., Renkonen R, Pietiläinen KH

Proteomics Clin Appl 13 (4) e1800173 [2019-07-00; online 2019-02-05]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Outlining the proton-conduction pathway in otopetrin channels.

Delemotte L

Nat. Struct. Mol. Biol. 26 (7) 528-530 [2019-07-00; online 2019-06-27]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain.

Bigalke JM, Aibara S, Roth R, ..., Amunts A, Sandmark J

Sci Adv 5 (7) eaau4202 [2019-07-00; online 2019-07-31]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

3D-Printed Whole Prostate Models with Tumor Hotspots Using Dual-Extruder Printer.

Liimatainen K, Latonen L, Kartasalo K, Ruusuvuori P

Annu Int Conf IEEE Eng Med Biol Soc 2019 (-) 2867-2871 [2019-07-00; online 2020-01-18]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

The Next Generation of Pattern Recognition Receptor Agonists: Improving Response Rates in Cancer Immunotherapy.

O' Donovan DH, Mao Y, Mele DA

Current medicinal chemistry 27 (34) 5654-5674 [2019-06-30; online 2019-06-30]

SciLifeLab Fellow Yumeng Mao

PubMed DOI Crossref

GPR44 as a Target for Imaging Pancreatic Beta-Cell Mass.

Eriksson O

Current diabetes reports 19 (8) 49 [2019-06-27; online 2019-06-27]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Serotype-specific evolutionary patterns of antimicrobial-resistant Salmonella enterica.

Liao J, Orsi RH, Carroll LM, ..., Zhang H, Wiedmann M

BMC Evol Biol BMC Evolutionary Biology 19 (1) 132 [2019-06-21; online 2019-06-21]

DDLS Fellow Laura Carroll

DOI Crossref

Shotgun Environmental DNA, Pollen, and Macrofossil Analysis of Lateglacial Lake Sediments From Southern Sweden

Parducci L, Alsos IG, Unneberg P, ..., Slotte T, Wohlfarth B

Front. Ecol. Evol. 7 (-) - [2019-06-20; online 2019-06-20]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Mitotically heritable effects of BMAA on striatal neural stem cell proliferation and differentiation.

Pierozan P, Karlsson O

Cell Death Dis 10 (7) 478 [2019-06-17; online 2019-06-17]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

Conformational switches control early maturation of the eukaryotic small ribosomal subunit.

Hunziker M, Barandun J, Buzovetsky O, ..., Molina H, Klinge S

Elife 8 (-) - [2019-06-17; online 2019-06-17]

Jonas Barandun SciLifeLab Fellow

PubMed DOI Crossref

Colitis-induced colorectal cancer and intestinal epithelial estrogen receptor beta impact gut microbiota diversity.

Ibrahim A, Hugerth LW, Hases L, ..., Engstrand L, Williams C

Int. J. Cancer 144 (12) 3086-3098 [2019-06-15; online 2019-01-11]

DDLS Fellow Luisa Hugerth

DOI Crossref

RMetD2: a tool for integration of relative transcriptomics data into Genome-scale metabolic models

Zhang C, Lee S, Bidkhori G, ..., Nielsen J, Mardinoglu A

- - (-) - [2019-06-06; online 2019-06-06]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Regulatory Immune Mechanisms beyond Regulatory T Cells.

Christoffersson G, von Herrath M

Trends Immunol. 40 (6) 482-491 [2019-06-00; online 2019-05-14]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Growth-driven displacement of protein aggregates along the cell length ensures partitioning to both daughter cells in Caulobacter crescentus.

Schramm FD, Schroeder K, Alvelid J, Testa I, Jonas K

Mol. Microbiol. 111 (6) 1430-1448 [2019-06-00; online 2019-04-03]

Ilaria Testa Kristina Jonas SciLifeLab Fellow

PubMed DOI Crossref

Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects.

Bergström CAS, Box K, Holm R, ..., Schäfer KJ, Teleki A

Eur J Pharm Biopharm 139 (-) 101-114 [2019-06-00; online 2019-03-09]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

Assembly and Characterization of a Pathogen Strain Collection for Produce Safety Applications: Pre-growth Conditions Have a Larger Effect on Peroxyacetic Acid Tolerance Than Strain Diversity.

Harrand AS, Kovac J, Carroll LM, ..., Kent DJ, Wiedmann M

Front Microbiol 10 (-) 1223 [2019-05-31; online 2019-05-31]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection.

Zychlinsky Scharff A, Rousseau M, Lacerda Mariano L, ..., Duffy D, Ingersoll MA

JCI Insight 5 (13) - [2019-05-30; online 2019-05-30]

Camila Consiglio DDLS Fellow

PubMed DOI Crossref

Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract.

Furter M, Sellin ME, Hansson GC, Hardt WD

Cell Reports 27 (9) 2665-2678.e3 [2019-05-28; online 2019-05-30]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Barcoded Consortium Infections Resolve Cell Type-Dependent Salmonella enterica Serovar Typhimurium Entry Mechanisms.

Di Martino ML, Ek V, Hardt WD, Eriksson J, Sellin ME

MBio 10 (3) - [2019-05-21; online 2019-05-21]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production.

Paivandy A, Eriksson J, Melo FR, Sellin ME, Pejler G

Cell death discovery 5 (1) 95 [2019-05-15; online 2019-05-15]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks.

Domingo-Prim J, Endara-Coll M, Bonath F, ..., Huertas P, Visa N

Nat Commun 10 (1) 2135 [2019-05-13; online 2019-05-13]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Mucosal-associated invariant T cells and oral microbiome in persistent apical periodontitis.

Davanian H, Gaiser RA, Silfverberg M, ..., Engstrand L, Sällberg Chen M

Int J Oral Sci 11 (2) 16 [2019-05-09; online 2019-05-09]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Mucispirillum schaedleri Antagonizes Salmonella Virulence to Protect Mice against Colitis.

Herp S, Brugiroux S, Garzetti D, ..., Berry D, Stecher B

Cell Host Microbe 25 (5) 681-694.e8 [2019-05-08; online 2019-04-18]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Multi-Omic Data Interpretation to Repurpose Subtype Specific Drug Candidates for Breast Cancer.

Turanli B, Karagoz K, Bidkhori G, ..., Mardinoglu A, Arga KY

Front Genet 10 (-) 420 [2019-05-07; online 2019-05-07]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Identification of Novel Mobilized Colistin Resistance Gene mcr-9 in a Multidrug-Resistant, Colistin-Susceptible Salmonella enterica Serotype Typhimurium Isolate.

Carroll LM, Gaballa A, Guldimann C, ..., Henderson LO, Wiedmann M

MBio 10 (3) - [2019-05-07; online 2019-05-07]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration.

Li D, Kular L, Vij M, ..., Jagodic M, Landén NX

Proc. Natl. Acad. Sci. U.S.A. 116 (19) 9443-9452 [2019-05-07; online 2019-04-24]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Long Time-Scale Atomistic Simulations of the Structure and Dynamics of Transcription Factor-DNA Recognition.

Liao Q, Lüking M, Krüger DM, ..., Kasson PM, Lynn Kamerlin SC

J Phys Chem B 123 (17) 3576-3590 [2019-05-02; online 2019-04-18]

SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Towards the new normal: Transcriptomic convergence and genomic legacy of the two subgenomes of an allopolyploid weed (Capsella bursa-pastoris).

Kryvokhyzha D, Milesi P, Duan T, ..., Glémin S, Lascoux M

PLoS Genet 15 (5) e1008131 [2019-05-00; online 2019-05-13]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Skalkidou A, Poromaa IS, Iliadis SI, ..., Freyhult E, Comasco E

Psychoneuroendocrinology 103 (-) 296-305 [2019-05-00; online 2019-02-07]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

GM1 locates to mature amyloid structures implicating a prominent role for glycolipid-protein interactions in Alzheimer pathology.

Michno W, Wehrli PM, Zetterberg H, Blennow K, Hanrieder J

Biochim Biophys Acta Proteins Proteom 1867 (5) 458-467 [2019-05-00; online 2018-09-28]

SciLifeLab Fellow Wojciech Michno

DOI Crossref

CoordinateCleaner: Standardized cleaning of occurrence records from biological collection databases

Zizka A, Silvestro D, Andermann T, ..., Zizka V, Antonelli A

Methods Ecol Evol 10 (5) 744-751 [2019-05-00; online 2019-02-24]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology.

Michno W, Nyström S, Wehrli P, ..., Zetterberg H, Hanrieder J

J Biol Chem 294 (17) 6719-6732 [2019-04-26; online 2019-02-27]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Non-Invasive Imaging Methodologies for Assessment of Radiation Damage to Bone Marrow and Kidneys from Peptide Receptor Radionuclide Therapy.

Ahlstedt J, Johansson E, Sydoff M, ..., Gram M, Eriksson O

Neuroendocrinology 110 (1-2) 130-138 [2019-04-19; online 2019-04-19]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling.

Sabantsev A, Levendosky RF, Zhuang X, Bowman GD, Deindl S

Nat Commun 10 (1) 1720 [2019-04-12; online 2019-04-12]

SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Receptor-Independent Transfer of Low Density Lipoprotein Cargo to Biomembranes.

Axmann M, Sezgin E, Karner A, ..., Stangl H, Plochberger B

Nano Lett. 19 (4) 2562-2567 [2019-04-10; online 2019-03-08]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

iFISH is a publically available resource enabling versatile DNA FISH to study genome architecture.

Gelali E, Girelli G, Matsumoto M, ..., Crosetto N, Bienko M

Nat Commun 10 (1) 1636 [2019-04-09; online 2019-04-09]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Spatiotemporal dynamics of molecular pathology in amyotrophic lateral sclerosis.

Maniatis S, Äijö T, Vickovic S, ..., Bonneau R, Phatnani H

Science (New York, N.Y.) 364 (6435) 89-93 [2019-04-05; online 2019-04-06]

Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection.

Garcia-Moreno M, Noerenberg M, Ni S, ..., Mohammed S, Castello A

Mol. Cell 74 (1) 196-211.e11 [2019-04-04; online 2019-02-21]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes.

Harms MJ, Li Q, Lee S, ..., Spalding KL, Boucher J

Cell Reports 27 (1) 213-225.e5 [2019-04-02; online 2019-04-04]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Case Reports of Pre-clinical Replication Studies in Metabolism and Diabetes.

von Herrath M, Pagni PP, Grove K, ..., Karlsen AE, Petersen JS

Cell Metab. 29 (4) 795-802 [2019-04-02; online 2019-03-14]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

New Phylogenomic Analysis of the Enigmatic Phylum Telonemia Further Resolves the Eukaryote Tree of Life.

Strassert JFH, Jamy M, Mylnikov AP, Tikhonenkov DV, Burki F

Mol. Biol. Evol. 36 (4) 757-765 [2019-04-01; online 2019-01-23]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Synthesis and preclinical evaluation of the CRTH2 antagonist [11C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass.

Eriksson J, Roy T, Sawadjoon S, ..., Eriksson O, Odell LR

Nucl. Med. Biol. 71 (-) 1-10 [2019-04-00; online 2019-04-13]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Prediction of individuals at high absolute risk of esophageal squamous cell carcinoma.

Wang QL, Lagergren J, Xie SH

Gastrointest Endosc 89 (4) 726-732.e2 [2019-04-00; online 2018-10-25]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

Measuring nanoscale diffusion dynamics in cellular membranes with super-resolution STED-FCS.

Sezgin E, Schneider F, Galiani S, ..., Lagerholm BC, Eggeling C

Nat Protoc 14 (4) 1054-1083 [2019-04-00; online 2019-03-06]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Liver macrophages regulate systemic metabolism through non-inflammatory factors.

Morgantini C, Jager J, Li X, ..., Bajgar A, Aouadi M

Nat Metab 1 (4) 445-459 [2019-04-00; online 2019-03-25]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning.

Turanli B, Zhang C, Kim W, ..., Arga KY, Mardinoglu A

EBioMedicine 42 (-) 386-396 [2019-04-00; online 2019-03-21]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Deep Learning in Image Cytometry: A Review.

Gupta A, Harrison PJ, Wieslander H, ..., Sintorn I, Wählby C

Cytometry A 95 (4) 366-380 [2019-04-00; online 2018-12-19]

DDLS Fellow Kimmo Kartasalo

DOI Crossref

Attempted syntheses of N-confused hydroporphyrins through modified Lindsey routes

Xiong R, Arkhypchuk AI, Eszter Borbas K

J. Porphyrins Phthalocyanines 23 (04n05) 589-598 [2019-04-00; online 2019-05-15]

Ruisheng Xiong SciLifeLab Fellow

PubMed DOI Crossref

A whole-brain atlas of monosynaptic input targeting four different cell types in the medial prefrontal cortex of the mouse.

Ährlund-Richter S, Xuan Y, van Lunteren JA, ..., Meletis K, Carlén M

Nat. Neurosci. 22 (4) 657-668 [2019-04-00; online 2019-03-18]

Iskra Pollak Dorocic SciLifeLab Fellow

PubMed DOI Crossref

Comprehensive kinetic and substrate specificity analysis of an arylsulfatase from Helix pomatia using mass spectrometry.

Correia MSP, Ballet C, Meistermann H, Conway LP, Globisch D

Bioorg. Med. Chem. 27 (6) 955-962 [2019-03-15; online 2019-01-30]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Expression of PD-L1 and PD-1 in Chemoradiotherapy-Naïve Esophageal and Gastric Adenocarcinoma: Relationship With Mismatch Repair Status and Survival.

Svensson MC, Borg D, Zhang C, ..., Leandersson K, Jirström K

Front Oncol 9 (-) 136 [2019-03-13; online 2019-03-13]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Gramicidin Increases Lipid Flip-Flop in Symmetric and Asymmetric Lipid Vesicles.

Doktorova M, Heberle FA, Marquardt D, ..., Weinstein H, Andersen OS

Biophys. J. 116 (5) 860-873 [2019-03-05; online 2019-01-25]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Vertical stratification of bacteria and archaea in sediments of a small boreal humic lake.

Rissanen AJ, Peura S, Mpamah PA, ..., Mäki A, Nykänen H

FEMS Microbiol. Lett. 366 (5) - [2019-03-01; online 2019-02-27]

Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function.

Liu Z, Zhang C, Lee S, ..., Boren J, Mardinoglu A

Metab. Eng. 52 (-) 263-272 [2019-03-00; online 2019-01-04]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Plant microRNAs in human sera are likely contaminants.

Fromm B, Kang W, Rovira C, ..., Friedländer MR, Tosar JP

J Nutr Biochem 65 (-) 139-140 [2019-03-00; online 2018-09-05]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Pervasive population genomic consequences of genome duplication in Arabidopsis arenosa.

Monnahan P, Kolář F, Baduel P, ..., Bomblies K, Yant L

Nat Ecol Evol 3 (3) 457-468 [2019-03-00; online 2019-02-25]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumours.

Lundberg A, Lindström LS, Li J, ..., Bergh J, Tobin NP

Breast Cancer Res. 21 (1) 34 [2019-02-28; online 2019-02-28]

Arian Lundberg DDLS Fellow

PubMed DOI Crossref

Long-term balancing selection drives evolution of immunity genes in Capsella.

Koenig D, Hagmann J, Li R, ..., Wright SI, Weigel D

Elife 8 (-) - [2019-02-26; online 2019-02-26]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Evolutionary Implications of the microRNA- and piRNA Complement of Lepidodermella squamata (Gastrotricha).

Fromm B, Tosar JP, Aguilera F, ..., Bachmann L, Hejnol A

Noncoding RNA 5 (1) 19 [2019-02-22; online 2019-02-22]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

First-in-class positron emission tomography tracer for the glucagon receptor.

Velikyan I, Haack T, Bossart M, ..., Wagner M, Eriksson O

EJNMMI Res 9 (1) 17 [2019-02-15; online 2019-02-15]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Heterogeneity of Metabolic Defects in Type 2 Diabetes and Its Relation to Reactive Oxygen Species and Alterations in Beta-Cell Mass.

Elksnis A, Martinell M, Eriksson O, Espes D

Front. Physiol. 10 (-) 107 [2019-02-13; online 2019-02-13]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Characterization of Emetic and Diarrheal Bacillus cereus Strains From a 2016 Foodborne Outbreak Using Whole-Genome Sequencing: Addressing the Microbiological, Epidemiological, and Bioinformatic Challenges.

Carroll LM, Wiedmann M, Mukherjee M, ..., Cole JA, Kovac J

Front Microbiol 10 (-) 144 [2019-02-12; online 2019-02-12]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection.

Wright SC, Kozielewicz P, Kowalski-Jahn M, ..., Carlsson J, Schulte G

Nat Commun 10 (1) 667 [2019-02-08; online 2019-02-08]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Kinetic modeling of the Calvin cycle identifies flux control and stable metabolomes in Synechocystis carbon fixation.

Janasch M, Asplund-Samuelsson J, Steuer R, Hudson EP

J. Exp. Bot. 70 (3) 973-983 [2019-02-05; online 2018-10-30]

Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

A New Computational Method for Membrane Compressibility: Bilayer Mechanical Thickness Revisited.

Doktorova M, LeVine MV, Khelashvili G, Weinstein H

Biophys. J. 116 (3) 487-502 [2019-02-05; online 2019-01-03]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Structural Patching Fosters Divergence of Mitochondrial Ribosomes.

Petrov AS, Wood EC, Bernier CR, ..., Brown A, Amunts A

Mol. Biol. Evol. 36 (2) 207-219 [2019-02-01; online 2018-12-06]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Smart scanning for low-illumination and fast RESOLFT nanoscopy in vivo.

Dreier J, Castello M, Coceano G, ..., Vicidomini G, Testa I

Nat Commun 10 (1) 556 [2019-02-01; online 2019-02-01]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Transcription-driven chromatin repression of Intragenic transcription start sites.

Nielsen M, Ard R, Leng X, ..., Pelechano V, Marquardt S

PLoS Genet 15 (2) e1007969 [2019-02-00; online 2019-02-01]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

How good are pathogenicity predictors in detecting benign variants?

Niroula A, Vihinen M

PLoS Comput Biol 15 (2) e1006481 [2019-02-00; online 2019-02-11]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysis.

Benfeitas R, Bidkhori G, Mukhopadhyay B, ..., Kunos G, Mardinoglu A

EBioMedicine 40 (-) 471-487 [2019-02-00; online 2018-12-31]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

TCF/LEF dependent and independent transcriptional regulation of Wnt/β-catenin target genes.

Doumpas N, Lampart F, Robinson MD, ..., Cantù C, Basler K

EMBO J. 38 (2) - [2019-01-15; online 2018-11-13]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

Discovery of KIRREL as a biomarker for prognostic stratification of patients with thin melanoma.

Lundgren S, Fagerström-Vahman H, Zhang C, ..., Nodin B, Jirström K

Biomark Res 7 (1) 1 [2019-01-14; online 2019-01-14]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Diarrheal bacterial pathogens and multi-resistant enterobacteria in the Choqueyapu River in La Paz, Bolivia.

Guzman-Otazo J, Gonzales-Siles L, Poma V, ..., Iñiguez V, Sjöling Å

PLoS ONE 14 (1) e0210735 [2019-01-14; online 2019-01-14]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Negative Association Between Allopregnanolone and Cerebral Serotonin Transporter Binding in Healthy Women of Fertile Age.

Sundström Poromaa I, Comasco E, Bäckström T, ..., Jensen P, Frokjaer VG

Front Psychol 9 (-) 2767 [2019-01-11; online 2019-01-11]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

The Circulating Transcriptome as a Source of Biomarkers for Melanoma.

Solé C, Tramonti D, Schramm M, ..., Middleton MR, Lawrie CH

Cancers (Basel) 11 (1) 70 [2019-01-10; online 2019-01-10]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Decreased Snow Cover Stimulates Under-Ice Primary Producers but Impairs Methanotrophic Capacity.

Garcia SL, Szekely AJ, Bergvall C, Schattenhofer M, Peura S

mSphere 4 (1) - [2019-01-09; online 2019-01-09]

Sarahi Garcia Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

The UNITE database for molecular identification of fungi: handling dark taxa and parallel taxonomic classifications.

Nilsson RH, Larsson KH, Taylor AFS, ..., Kõljalg U, Abarenkov K

Nucleic Acids Res. 47 (D1) D259-D264 [2019-01-08; online 2018-10-30]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Ascetosporea.

Bass D, Ward GM, Burki F

Curr. Biol. 29 (1) R7-R8 [2019-01-07; online 2019-01-09]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium.

Westermann AJ, Venturini E, Sellin ME, ..., Hardt WD, Vogel J

MBio 10 (1) - [2019-01-02; online 2019-01-02]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System.

de Jong JW, Afjei SA, Pollak Dorocic I, ..., Deisseroth K, Lammel S

Neuron 101 (1) 133-151.e7 [2019-01-02; online 2018-11-29]

Iskra Pollak Dorocic SciLifeLab Fellow

PubMed DOI Crossref

Large expert-curated database for benchmarking document similarity detection in biomedical literature search.

Brown P, RELISH Consortium , Zhou Y

Database (Oxford) 2019 (-) - [2019-01-01; online 2019-01-01]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Allele Phasing Greatly Improves the Phylogenetic Utility of Ultraconserved Elements.

Andermann T, Fernandes AM, Olsson U, ..., Faircloth BC, Antonelli A

Syst. Biol. 68 (1) 32-46 [2019-01-01; online 2018-05-18]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

Revisions to the Classification, Nomenclature, and Diversity of Eukaryotes.

Adl SM, Bass D, Lane CE, ..., Zlatogursky V, Zhang Q

J. Eukaryot. Microbiol. 66 (1) 4-119 [2019-01-00; online 2018-09-27]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Phylogenomics supports the monophyly of the Cercozoa.

Irwin NAT, Tikhonenkov DV, Hehenberger E, ..., Burki F, Keeling PJ

Mol. Phylogenet. Evol. 130 (-) 416-423 [2019-01-00; online 2018-10-11]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Introducing ribosomal tandem repeat barcoding for fungi.

Wurzbacher C, Larsson E, Bengtsson-Palme J, ..., Kagami M, Nilsson RH

Mol Ecol Resour 19 (1) 118-127 [2019-01-00; online 2018-10-24]

DDLS Fellow Johan Bengtsson-Palme

DOI Crossref

Next-Generation Sequencing

Wiedmann M, Carroll LM

- - (-) 376-383 [2019-00-00; online 2019-00-00]

DDLS Fellow Laura Carroll

DOI Crossref

Nanostructured Minerals and Vitamins for Food Fortification and Food Supplementation

Knijnenburg JTN, Posavec L, Teleki A

- - (-) 63-98 [2019-00-00; online 2019-00-00]

Alexandra Teleki SciLifeLab Fellow

DOI Crossref

Assessment and Management of Risks Associated With Antibiotic Resistance in the Environment

Bengtsson-Palme J

Management of Emerging Public Health Issues and Risks: Multidisciplinary Approaches to the Changing Environment - (-) 243-263 [2019-00-00; online 2019-00-00]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass.

Jahan M, Johnström P, Selvaraju RK, ..., Halldin C, Eriksson O

EJNMMI Res 8 (1) 113 [2018-12-27; online 2018-12-27]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Phenotypic and genomic analyses of bacteriophages targeting environmental and clinical CS3-expressing enterotoxigenic Escherichia coli (ETEC) strains.

Chakraborty S, von Mentzer A, Begum YA, ..., Camilli A, Qadri F

PLoS ONE 13 (12) e0209357 [2018-12-20; online 2018-12-20]

Astrid von Mentzer DDLS Fellow

PubMed DOI Crossref

CD45 exclusion- and cross-linking-based receptor signaling together broaden FcεRI reactivity.

Felce JH, Sezgin E, Wane M, ..., Eggeling C, Davis SJ

Sci Signal 11 (561) - [2018-12-18; online 2018-12-18]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

acI Actinobacteria Assemble a Functional Actinorhodopsin with Natively Synthesized Retinal.

Dwulit-Smith JR, Hamilton JJ, Stevenson DM, ..., McMahon KD, Forest KT

Applied and environmental microbiology 84 (24) - [2018-12-15; online 2018-11-30]

Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks.

Bonath F, Domingo-Prim J, Tarbier M, Friedländer MR, Visa N

Nucleic Acids Res. 46 (22) 11869-11882 [2018-12-14; online 2018-11-13]

DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow

PubMed DOI Crossref

Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes.

Bidkhori G, Benfeitas R, Klevstig M, ..., Boren J, Mardinoglu A

Proc. Natl. Acad. Sci. U.S.A. 115 (50) E11874-E11883 [2018-12-11; online 2018-11-27]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

miRTrace reveals the organismal origins of microRNA sequencing data.

Kang W, Eldfjell Y, Fromm B, ..., Biryukova I, Friedländer MR

Genome Biol. 19 (1) 213 [2018-12-04; online 2018-12-04]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

FZD5 is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs.

Wright SC, Cañizal MCA, Benkel T, ..., Schulte G, Hoffmann C

Sci Signal 11 (559) eaar5536 [2018-12-04; online 2018-12-04]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Tumor suppressor PNRC1 blocks rRNA maturation by recruiting the decapping complex to the nucleolus.

Gaviraghi M, Vivori C, Pareja Sanchez Y, ..., Cittaro D, Tonon G

EMBO J. 37 (23) - [2018-12-03; online 2018-10-29]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Methanogens and Iron-Reducing Bacteria: the Overlooked Members of Mercury-Methylating Microbial Communities in Boreal Lakes.

Bravo AG, Peura S, Buck M, ..., Björn E, Bertilsson S

Applied and environmental microbiology 84 (23) - [2018-12-01; online 2018-11-15]

Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

Metaxa2 Database Builder: enabling taxonomic identification from metagenomic or metabarcoding data using any genetic marker.

Bengtsson-Palme J, Richardson RT, Meola M, ..., Hartmann M, Nilsson RH

Bioinformatics 34 (23) 4027-4033 [2018-12-01; online 2018-06-19]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Multiscale patterns and drivers of arbuscular mycorrhizal fungal communities in the roots and root-associated soil of a wild perennial herb.

Rasmussen PU, Hugerth LW, Blanchet FG, ..., Lindahl BD, Tack AJM

New Phytol. 220 (4) 1248-1261 [2018-12-00; online 2018-03-24]

DDLS Fellow Luisa Hugerth

DOI Crossref

HYPERPARAMETER OPTIMIZATION FOR APPROXIMATE BAYESIAN COMPUTATION

Singh P, Hellander A

- - (-) - [2018-12-00; online 2018-12-00]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer.

Gotthardt M, Eizirik DL, Aanstoot HJ, ..., Cnop M, Brom M

Diabetologia 61 (12) 2516-2519 [2018-12-00; online 2018-10-03]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Cost-effective generation of precise label-free quantitative proteomes in high-throughput by microLC and data-independent acquisition

Vowinckel J, Zelezniak A, Bruderer R, ..., Reiter L, Ralser M

Sci Rep 8 (1) - [2018-12-00; online 2018-03-12]

Affiliated researcher Aleksej Zelezniak SciLifeLab Fellow

PubMed DOI Crossref

Control of hepatic gluconeogenesis by Argonaute2.

Yan X, Wang Z, Bishop CA, ..., Willnow TE, Poy MN

Mol Metab 18 (-) 15-24 [2018-12-00; online 2018-10-09]

DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow

DOI Crossref

Bridging gaps in transposable element research with single-molecule and single-cell technologies

Kutter C, Jern P, Suh A

Mobile DNA 9 (1) - [2018-12-00; online 2018-12-06]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

RollFISH achieves robust quantification of single-molecule RNA biomarkers in paraffin-embedded tumor tissue samples.

Wu C, Simonetti M, Rossell C, ..., Crosetto N, Nilsson M

Commun Biol 1 (1) 209 [2018-11-28; online 2018-11-28]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice.

Håversen L, Sundelin JP, Mardinoglu A, ..., Levin M, Borén J

Sci Rep 8 (1) 16973 [2018-11-19; online 2018-11-19]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Methanomethylophilus alvus Mx1201 Provides Basis for Mutual Orthogonal Pyrrolysyl tRNA/Aminoacyl-tRNA Synthetase Pairs in Mammalian Cells.

Meineke B, Heimgärtner J, Lafranchi L, Elsässer SJ

ACS chemical biology 13 (11) 3087-3096 [2018-11-16; online 2018-10-12]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

PREQUAL: detecting non-homologous characters in sets of unaligned homologous sequences.

Whelan S, Irisarri I, Burki F

Bioinformatics 34 (22) 3929-3930 [2018-11-15; online 2018-06-06]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Structural Characterization of Agonist Binding to Protease-Activated Receptor 2 through Mutagenesis and Computational Modeling.

Kennedy AJ, Ballante F, Johansson JR, ..., Nordqvist A, Carlsson J

ACS pharmacology & translational science 1 (2) 119-133 [2018-11-09; online 2018-10-16]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

A Network-Based Cancer Drug Discovery: From Integrated Multi-Omics Approaches to Precision Medicine.

Turanli B, Karagoz K, Gulfidan G, ..., Mardinoglu A, Arga KY

Curr. Pharm. Des. 24 (32) 3778-3790 [2018-11-07; online 2018-11-07]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Forces drive basement membrane invasion in Caenorhabditis elegans.

Cáceres R, Bojanala N, Kelley LC, ..., Sherwood DR, Plastino J

Proc. Natl. Acad. Sci. U.S.A. 115 (45) 11537-11542 [2018-11-06; online 2018-10-22]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Accurate In Silico Modeling of Asymmetric Bilayers Based on Biophysical Principles.

Doktorova M, Weinstein H

Biophys. J. 115 (9) 1638-1643 [2018-11-06; online 2018-09-15]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon.

Sahlin K, Tomaszkiewicz M, Makova KD, Medvedev P

Nat Commun 9 (1) 4601 [2018-11-02; online 2018-11-02]

Kristoffer Sahlin SciLifeLab Fellow

PubMed DOI Crossref

Nearly Neutral Evolution across the Drosophila melanogaster Genome.

Castellano D, James J, Eyre-Walker A

Mol. Biol. Evol. 35 (11) 2685-2694 [2018-11-01; online 2018-11-13]

DDLS Fellow Jennifer James

PubMed DOI Crossref

microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function.

Langlet F, Tarbier M, Haeusler RA, ..., Friedländer MR, Accili D

Mol Metab 17 (-) 49-60 [2018-11-00; online 2018-08-11]

DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow

PubMed DOI Crossref

Uncovering the regional localization of inhaled salmeterol retention in the lung.

Bäckström E, Hamm G, Nilsson A, ..., Goodwin RJA, Fridén M

Drug Deliv 25 (1) 838-845 [2018-11-00; online 2018-03-29]

Affiliated researcher

PubMed DOI Crossref

Transfection of crayfish hematopoietic tissue cells.

Shi H, Ruan L, Söderhäll I, Söderhäll K, Xu X

Dev. Comp. Immunol. 88 (-) 70-76 [2018-11-00; online 2018-07-09]

Affiliated researcher

DOI Crossref

QCM mass underestimation in molecular biotechnology: Proximity ligation assay for norovirus detection as a case study

Neumann F, Madaboosi N, Hernández-Neuta I, ..., Mecea V, Nilsson M

Sensors and Actuators B: Chemical 273 (-) 742-750 [2018-11-00; online 2018-11-00]

Affiliated researcher

PubMed DOI Crossref

How to minimize dye-induced perturbations while studying biomembrane structure and dynamics: PEG linkers as a rational alternative.

Mobarak E, Javanainen M, Kulig W, ..., Rog T, Vattulainen I

Biochim Biophys Acta Biomembr 1860 (11) 2436-2445 [2018-11-00; online 2018-07-18]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Gene-environment interaction of monoamine oxidase A in relation to antisocial behaviour: current and future directions.

Nilsson KW, Åslund C, Comasco E, Oreland L

J Neural Transm (Vienna) 125 (11) 1601-1626 [2018-11-00; online 2018-06-07]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

First report of an mcr-1-harboring Salmonella enterica subsp. enterica serotype 4,5,12:i:- strain isolated from blood of a patient in Switzerland.

Carroll LM, Zurfluh K, Jang H, ..., Stephan R, Guldimann C

Int. J. Antimicrob. Agents 52 (5) 740-741 [2018-11-00; online 2018-08-10]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Barcoded solid-phase RNA capture for Spatial Transcriptomics profiling in mammalian tissue sections.

Salmén F, Ståhl PL, Mollbrink A, ..., Frisén J, Lundeberg J

Nat Protoc 13 (11) 2501-2534 [2018-11-00; online 2018-10-26]

Sanja Vickovic SciLifeLab Fellow

DOI Crossref

An optimized shape descriptor based on structural properties of networks

Miranda GHB, Machicao J, Bruno OM

Digital Signal Processing 82 (-) 216-229 [2018-11-00; online 2018-11-00]

Gisele Miranda SciLifeLab Fellow

DOI Crossref

Ribosome Profiling of Synechocystis Reveals Altered Ribosome Allocation at Carbon Starvation

Karlsen J, Asplund-Samuelsson J, Thomas Q, Jahn M, Hudson EP

mSystems 3 (5) - [2018-10-30; online 2018-10-30]

Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

Detection of post-translational modifications using solid-phase proximity ligation assay.

Oliveira FMS, Mereiter S, Lönn P, ..., Reis CA, Kamali-Moghaddam M

N Biotechnol 45 (-) 51-59 [2018-10-25; online 2017-10-31]

Affiliated researcher

PubMed DOI Crossref

Combination of phage and Gram-positive bacterial display of human antibody repertoires enables isolation of functional high affinity binders.

Hu FJ, Volk AL, Persson H, ..., Uhlen M, Rockberg J

N Biotechnol 45 (-) 80-88 [2018-10-25; online 2017-08-01]

Affiliated researcher

PubMed DOI Crossref

A myopic perspective on the future of protein diagnostics.

Landegren U, Al-Amin RA, Björkesten J

N Biotechnol 45 (-) 14-18 [2018-10-25; online 2018-01-05]

Affiliated researcher

PubMed DOI Crossref

A Robust Proton Flux (pHlux) Assay for Studying the Function and Inhibition of the Influenza A M2 Proton Channel.

Santner P, Martins JMDS, Laursen JS, ..., Willemoës M, Lindorff-Larsen K

Biochemistry 57 (41) 5949-5956 [2018-10-16; online 2018-10-03]

Lars Behrendt SciLifeLab Fellow

PubMed DOI Crossref

Chemoselective Probe Containing a Unique Bioorthogonal Cleavage Site for Investigation of Gut Microbiota Metabolism.

Garg N, Conway LP, Ballet C, ..., Löhr JM, Globisch D

Angew. Chem. Int. Ed. Engl. 57 (42) 13805-13809 [2018-10-15; online 2018-09-20]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Noninvasive Urine Biomarker Lateral Flow Immunoassay for Monitoring Active Onchocerciasis.

Shirey RJ, Globisch D, Eubanks LM, Hixon MS, Janda KD

ACS Infect Dis 4 (10) 1423-1431 [2018-10-12; online 2018-09-21]

Daniel Globisch SciLifeLab Fellow

DOI Crossref

Quantifying point-mutations in shotgun metagenomic data

Magesh S, Jonsson V, Bengtsson-Palme J

bioRxiv preprint - (-) - [2018-10-11; online 2018-10-11]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Growth of Cyanobacteria Is Constrained by the Abundance of Light and Carbon Assimilation Proteins.

Jahn M, Vialas V, Karlsen J, ..., Käll L, Hudson EP

Cell Reports 25 (2) 478-486.e8 [2018-10-09; online 2018-10-12]

Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

Rapid Isolation of the Mitoribosome from HEK Cells.

Aibara S, Andréll J, Singh V, Amunts A

J Vis Exp - (140) - [2018-10-04; online 2018-10-04]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Conceptual and empirical advances in Neotropical biodiversity research.

Antonelli A, Ariza M, Albert J, ..., Zizka A, Edwards SV

PeerJ 6 (-) e5644 [2018-10-04; online 2018-10-04]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

Reconstitution of immune cell interactions in free-standing membranes.

Jenkins E, Santos AM, O'Brien-Ball C, ..., Eggeling C, Sezgin E

J. Cell. Sci. 132 (4) - [2018-10-02; online 2018-10-02]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Bacteriophages Synergize with the Gut Microbial Community To Combat Salmonella.

Hu YOO, Hugerth LW, Bengtsson C, ..., Du J, Engstrand L

mSystems 3 (5) - [2018-10-02; online 2018-10-02]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA.

Delemotte L

J. Gen. Physiol. 150 (10) 1356-1359 [2018-10-01; online 2018-08-24]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Determining the molecular basis of voltage sensitivity in membrane proteins.

Kasimova MA, Lindahl E, Delemotte L

J. Gen. Physiol. 150 (10) 1444-1458 [2018-10-01; online 2018-08-27]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

High Cell Density Perfusion Culture has a Maintained Exoproteome and Metabolome.

Zamani L, Lundqvist M, Zhang Y, ..., Rockberg J, Chotteau V

Biotechnol J 13 (10) e1800036 [2018-10-00; online 2018-07-13]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Genome-wide binding of transcription factor ZEB1 in triple-negative breast cancer cells.

Maturi V, Enroth S, Heldin CH, Moustakas A

J. Cell. Physiol. 233 (10) 7113-7127 [2018-10-00; online 2018-05-10]

Affiliated researcher

PubMed DOI Crossref

Genomes from uncultivated prokaryotes: a comparison of metagenome-assembled and single-amplified genomes.

Alneberg J, Karlsson CMG, Divne AM, ..., Andersson AF, Pinhassi J

Microbiome 6 (1) 173 [2018-09-28; online 2018-09-28]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

ESS: A Tool for Genome-Scale Quantification of Essentiality Score for Reaction/Genes in Constraint-Based Modeling.

Zhang C, Bidkhori G, Benfeitas R, ..., Uhlén M, Mardinoglu A

Front. Physiol. 9 (-) 1355 [2018-09-28; online 2018-09-28]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Bioanalytical advantages of a novel recombinant apyrase enzyme in ATP-based bioluminescence methods.

Pavankumar AR, Zelenin S, Lundin A, ..., Achour A, Russom A

Anal. Chim. Acta 1025 (-) 118-123 [2018-09-26; online 2018-04-26]

Affiliated researcher

PubMed DOI Crossref

Effects of Design Choices on the Stiffness of Wireframe DNA Origami Structures.

Benson E, Mohammed A, Rayneau-Kirkhope D, ..., Orponen P, Högberg B

ACS Nano 12 (9) 9291-9299 [2018-09-25; online 2018-09-06]

Erik Benson SciLifeLab Fellow

PubMed DOI Crossref

Maternal gut and breast milk microbiota affect infant gut antibiotic resistome and mobile genetic elements.

Pärnänen K, Karkman A, Hultman J, ..., Satokari R, Virta M

Nat Commun 9 (1) 3891 [2018-09-24; online 2018-09-24]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome.

Lovric A, Granér M, Bjornson E, ..., Mardinoglu A, Boren J

Sci Rep 8 (1) 14200 [2018-09-21; online 2018-09-21]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Meta-Analysis of Adiponectin as a Biomarker for the Detection of Metabolic Syndrome.

Liu Z, Liang S, Que S, ..., Zheng S, Mardinoglu A

Front. Physiol. 9 (-) 1238 [2018-09-19; online 2018-09-19]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Focal Adhesion Kinase and ROCK Signaling Are Switch-Like Regulators of Human Adipose Stem Cell Differentiation towards Osteogenic and Adipogenic Lineages.

Hyväri L, Ojansivu M, Juntunen M, ..., Miettinen S, Vanhatupa S

Stem Cells Int 2018 (-) 2190657 [2018-09-12; online 2018-09-12]

DDLS Fellow Kimmo Kartasalo

DOI Crossref

Phylogeny and Systematics of Kewa (Kewaceae)

Thulin M, Larsson A, Edwards EJ, Moore AJ

Systematic Botany 43 (3) 689-700 [2018-09-10; online 2018-09-10]

Affiliated researcher

PubMed DOI Crossref

Excitation- and Emission-Wavelength-Based Multiplex Spectroscopy Using Red-Absorbing Near-Infrared-Emitting Lanthanide Complexes.

Xiong R, Mara D, Liu J, Van Deun R, Borbas KE

Journal of the American Chemical Society 140 (35) 10975-10979 [2018-09-05; online 2018-08-23]

Ruisheng Xiong SciLifeLab Fellow

PubMed DOI Crossref

Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells.

Srpan K, Ambrose A, Karampatzakis A, ..., Önfelt B, Davis DM

J. Cell Biol. 217 (9) 3267-3283 [2018-09-03; online 2018-07-02]

Affiliated researcher

PubMed DOI Crossref

Promoter Usage and Dynamics in Vascular Smooth Muscle Cells Exposed to Fibroblast Growth Factor-2 or Interleukin-1β.

Alhendi AMN, Patrikakis M, Daub CO, ..., Arner E, Khachigian LM

Sci Rep 8 (1) 13164 [2018-09-03; online 2018-09-03]

Affiliated researcher

PubMed DOI Crossref

Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain.

Bazov I, Sarkisyan D, Kononenko O, ..., Yakovleva T, Bakalkin G

Cereb. Cortex 28 (9) 3129-3142 [2018-09-01; online 2017-10-03]

Affiliated researcher

PubMed DOI Crossref

Comparative analysis of tissue reconstruction algorithms for 3D histology.

Kartasalo K, Latonen L, Vihinen J, ..., Nykter M, Ruusuvuori P

Bioinformatics 34 (17) 3013-3021 [2018-09-01; online 2018-04-24]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

The pro-inflammatory role of platelets in cancer.

Olsson AK, Cedervall J

Platelets 29 (6) 569-573 [2018-09-00; online 2018-03-27]

Affiliated researcher

PubMed DOI Crossref

The downfall of TBA-354 - a possible explanation for its neurotoxicity via mass spectrometric imaging.

Ntshangase S, Shobo A, Kruger HG, ..., Govender T, Baijnath S

Xenobiotica 48 (9) 938-944 [2018-09-00; online 2017-10-13]

Affiliated researcher

PubMed DOI Crossref

The Protozoan Parasite Toxoplasma gondii Selectively Reprograms the Host Cell Translatome.

Leroux LP, Lorent J, Graber TE, ..., Larsson O, Jaramillo M

Infect. Immun. 86 (9) - [2018-09-00; online 2018-08-22]

Affiliated researcher

PubMed DOI Crossref

Targeting ATR in cancer.

Lecona E, Fernandez-Capetillo O

Nat. Rev. Cancer 18 (9) 586-595 [2018-09-00; online 2018-06-15]

Affiliated researcher

PubMed DOI Crossref

Systematic overexpression study to find target enzymes enhancing production of terpenes in Synechocystis PCC 6803, using isoprene as a model compound.

Englund E, Shabestary K, Hudson EP, Lindberg P

Metab. Eng. 49 (-) 164-177 [2018-09-00; online 2018-07-17]

Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

Survival of Campylobacter jejuni and Campylobacter coli water isolates in lake and well water.

Nilsson A, Johansson C, Skarp A, ..., Bertilsson S, Rautelin H

APMIS 126 (9) 762-770 [2018-09-00; online 2018-08-31]

Affiliated researcher

PubMed DOI Crossref

Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer.

Bruun J, Sveen A, Barros R, ..., Almeida R, Lothe RA

Mol Oncol 12 (9) 1639-1655 [2018-09-00; online 2018-08-15]

Affiliated researcher

PubMed DOI Crossref

Preparation of asymmetric phospholipid vesicles for use as cell membrane models.

Doktorova M, Heberle FA, Eicher B, ..., Pabst G, Marquardt D

Nat Protoc 13 (9) 2086-2101 [2018-09-00; online 2018-09-08]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Multi-ethnic genome-wide association study for atrial fibrillation.

Roselli C, Chaffin MD, Weng LC, ..., Lunetta KL, Ellinor PT

Nat. Genet. 50 (9) 1225-1233 [2018-09-00; online 2018-06-11]

Affiliated researcher

PubMed DOI Crossref

Mechanisms for stalled replication fork stabilization: new targets for synthetic lethality strategies in cancer treatments.

Liao H, Ji F, Helleday T, Ying S

EMBO Rep. 19 (9) - [2018-09-00; online 2018-08-13]

Affiliated researcher

PubMed DOI Crossref

Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes.

Ruhrmann S, Ewing E, Piket E, ..., Piehl F, Jagodic M

Mult. Scler. 24 (10) 1288-1300 [2018-09-00; online 2017-08-02]

Affiliated researcher

PubMed DOI Crossref

Germline variation in the oxidative DNA repair genes NUDT1 and OGG1 is not associated with hereditary colorectal cancer or polyposis.

Mur P, Jemth AS, Bevc L, ..., Helleday T, Valle L

Hum. Mutat. 39 (9) 1214-1225 [2018-09-00; online 2018-07-04]

Affiliated researcher

PubMed DOI Crossref

Developing reduced SNP assays from whole-genome sequence data to estimate introgression in an organism with complex genetic patterns, the Iberian honeybee ( Apis mellifera iberiensis).

Henriques D, Parejo M, Vignal A, ..., Webster MT, Pinto MA

Evol Appl 11 (8) 1270-1282 [2018-09-00; online 2018-03-30]

Affiliated researcher

PubMed DOI Crossref

Detailed analysis of HTT repeat elements in human blood using targeted amplification-free long-read sequencing.

Höijer I, Tsai YC, Clark TA, ..., Gyllensten U, Ameur A

Hum. Mutat. 39 (9) 1262-1272 [2018-09-00; online 2018-07-12]

Affiliated researcher

PubMed DOI Crossref

Characterization of a cold-active transglutaminase from a crayfish, Pacifastacus leniusculus.

Sirikharin R, Söderhäll I, Söderhäll K

Fish Shellfish Immunol. 80 (-) 546-549 [2018-09-00; online 2018-06-27]

Affiliated researcher

PubMed DOI Crossref

Autoantibody profiling reveals four protein candidate autoantigens associated with systemic lupus erythematosus.

Frostegård J, Hellström C, Nilsson P, Frostegård AG, Ajeganova S

Lupus 27 (10) 1670-1678 [2018-09-00; online 2018-07-24]

Affiliated researcher

PubMed DOI Crossref

Assessment modalities of non-ionizing three-dimensional images for the quantification of facial morphology, symmetry, and appearance in cleft lip and palate: a systematic review.

Thierens LAM, De Roo NMC, De Pauw GAM, Brusselaers N

Int J Oral Maxillofac Surg 47 (9) 1095-1105 [2018-09-00; online 2018-06-05]

Affiliated researcher

PubMed DOI Crossref

An update on the role of type I interferons in systemic lupus erythematosus and Sjögren's syndrome.

Thorlacius GE, Wahren-Herlenius M, Rönnblom L

Curr Opin Rheumatol 30 (5) 471-481 [2018-09-00; online 2018-06-12]

Affiliated researcher

PubMed DOI Crossref

A fine-needle aspiration-based protein signature discriminates benign from malignant breast lesions.

Franzén B, Kamali-Moghaddam M, Alexeyenko A, ..., Landegren U, Lewensohn R

Mol Oncol 12 (9) 1415-1428 [2018-09-00; online 2018-08-09]

Affiliated researcher

PubMed DOI Crossref

Top-Down Fabricated Silicon Nanowire Arrays for Field-Effect Detection of Prostate-Specific Antigen

Rani D, Pachauri V, Madaboosi N, ..., Conde JP, Ingebrandt S

ACS Omega 3 (8) 8471-8482 [2018-08-31; online 2018-08-01]

Affiliated researcher

PubMed DOI Crossref

Ca2+-binding protein NECAB2 facilitates inflammatory pain hypersensitivity.

Zhang MD, Su J, Adori C, ..., Harkany T, Hökfelt T

J. Clin. Invest. 128 (9) 3757-3768 [2018-08-31; online 2018-07-30]

Affiliated researcher

PubMed DOI Crossref

Mapping the Interface of a GPCR Dimer: A Structural Model of the A2A Adenosine and D2 Dopamine Receptor Heteromer.

Borroto-Escuela DO, Rodriguez D, Romero-Fernandez W, ..., Fuxe K, Carlsson J

Front. Pharmacol. 9 (-) 829 [2018-08-30; online 2018-08-30]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Eleven percent intact PGM3 in a severely immunodeficient patient with a novel splice-site mutation, a case report.

Lundin KE, Wang Q, Hamasy A, ..., Ekwall O, Smith CIE

BMC Pediatr 18 (1) 285 [2018-08-29; online 2018-08-29]

Affiliated researcher

PubMed DOI Crossref

Building of neomycin-nucleobase-amino acid conjugates for the inhibition of oncogenic miRNAs biogenesis.

Vo DD, Becquart C, Tran TPA, ..., Staedel C, Duca M

Org. Biomol. Chem. 16 (34) 6262-6274 [2018-08-29; online 2018-08-18]

Affiliated researcher

PubMed DOI Crossref

Statistical Analysis of Scanning Fluorescence Correlation Spectroscopy Data Differentiates Free from Hindered Diffusion.

Schneider F, Waithe D, Lagerholm BC, ..., Eggeling C, Fritzsche M

ACS Nano 12 (8) 8540-8546 [2018-08-28; online 2018-07-26]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment.

Dyczynski M, Vesterlund M, Björklund AC, ..., Tamm KP, Nilsson R

Cell Death Dis 9 (9) 846 [2018-08-28; online 2018-08-28]

Affiliated researcher

DOI Crossref

Direct observation of rotation-coupled protein diffusion along DNA on the microsecond timescale

Marklund E, Amselem E, Kipper K, ..., Deindl S, Elf J

- - (-) - [2018-08-27; online 2018-08-27]

Emil Marklund SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

A Protein-Based Encapsulation System with Calcium-Controlled Cargo Loading and Detachment.

Lizatović R, Assent M, Barendregt A, ..., Wennmalm S, André I

Angew. Chem. Int. Ed. Engl. 57 (35) 11334-11338 [2018-08-27; online 2018-07-30]

Affiliated researcher

PubMed DOI Crossref

Association of tamoxifen resistance and lipid reprogramming in breast cancer.

Hultsch S, Kankainen M, Paavolainen L, ..., Pietiäinen V, Kallioniemi O

BMC Cancer 18 (1) 850 [2018-08-24; online 2018-08-24]

Affiliated researcher

PubMed DOI Crossref

Stereotypic Immune System Development in Newborn Children.

Olin A, Henckel E, Chen Y, ..., Bohlin K, Brodin P

Cell 174 (5) 1277-1292.e14 [2018-08-23; online 2018-08-25]

Affiliated researcher

PubMed DOI Crossref

Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development.

Marques S, van Bruggen D, Vanichkina DP, ..., Taft RJ, Castelo-Branco G

Dev. Cell 46 (4) 504-517.e7 [2018-08-20; online 2018-08-02]

Affiliated researcher

DOI Crossref

Sulfonimidamides: Synthesis and Applications in Preparative Organic Chemistry

Nandi GC, Arvidsson PI

Adv. Synth. Catal. 360 (16) 2976-3001 [2018-08-17; online 2018-05-25]

Affiliated researcher

PubMed DOI Crossref

Role of Gln222 in Photoswitching of Aequorea Fluorescent Proteins: A Twisting and H-Bonding Affair?

Storti B, Margheritis E, Abbandonato G, ..., Nifosì R, Bizzarri R

ACS chemical biology 13 (8) 2082-2093 [2018-08-17; online 2018-06-19]

Affiliated researcher Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Enhanced photon collection enables four dimensional fluorescence nanoscopy of living systems.

Masullo LA, Bodén A, Pennacchietti F, ..., Ratz M, Testa I

Nat Commun 9 (1) 3281 [2018-08-16; online 2018-08-16]

Affiliated researcher Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

The binding of Chp2's chromodomain to methylated H3K9 is essential for Chp2's role in heterochromatin assembly in fission yeast.

Maksimov V, Oya E, Tanaka M, ..., Bjerling P, Nakayama JI

PLoS ONE 13 (8) e0201101 [2018-08-15; online 2018-08-15]

Affiliated researcher

PubMed DOI Crossref

Surface Display of Small Affinity Proteins on Synechocystis sp. Strain PCC 6803 Mediated by Fusion to the Major Type IV Pilin PilA1.

Cengic I, Uhlén M, Hudson EP

J. Bacteriol. 200 (16) - [2018-08-15; online 2018-07-25]

Affiliated researcher Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

Characterization of avian influenza virus attachment patterns to human and pig tissues.

Eriksson P, Lindskog C, Engholm E, ..., Jourdain E, Ellström P

Sci Rep 8 (1) 12215 [2018-08-15; online 2018-08-15]

Affiliated researcher

PubMed DOI Crossref

A Decomposition Method for Global Evaluation of Shannon Entropy and Local Estimations of Algorithmic Complexity.

Zenil H, Hernández-Orozco S, Kiani NA, ..., Rueda-Toicen A, Tegnér J

Entropy 20 (8) 605 [2018-08-15; online 2018-08-15]

Affiliated researcher

PubMed DOI Crossref

Novel Autotrophic Organisms Contribute Significantly to the Internal Carbon Cycling Potential of a Boreal Lake.

Peura S, Buck M, Aalto SL, ..., Nykänen H, Eiler A

MBio 9 (4) - [2018-08-14; online 2018-08-14]

Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

Predicting drug permeability through skin using molecular dynamics simulation.

Lundborg M, Wennberg CL, Narangifard A, Lindahl E, Norlén L

J Control Release 283 (-) 269-279 [2018-08-10; online 2018-06-01]

Affiliated researcher

PubMed DOI Crossref

Stationary and portable sequencing-based approaches for tracing wastewater contamination in urban stormwater systems.

Hu YOO, Ndegwa N, Alneberg J, ..., Fagerberg J, Andersson AF

Sci Rep 8 (1) 11907 [2018-08-09; online 2018-08-09]

Affiliated researcher

PubMed DOI Crossref

SURGE complex of Plasmodium falciparum in the rhoptry-neck (SURFIN4.2-RON4-GLURP) contributes to merozoite invasion.

Quintana MDP, Ch'ng JH, Zandian A, ..., Chan S, Wahlgren M

PLoS ONE 13 (8) e0201669 [2018-08-09; online 2018-08-09]

Affiliated researcher

DOI Crossref

Measuring genome-wide genetic variation to reassess subspecies classifications in Dodonaea viscosa (Sapindaceae)

Christmas MJ, Biffin E, Lowe AJ

Aust. J. Bot. 66 (4) 287-297 [2018-08-08; online 2018-07-09]

Affiliated researcher

PubMed DOI Crossref

Proteomic Biomarkers for Incident Aortic Stenosis Requiring Valvular Replacement.

Ljungberg J, Janiec M, Bergdahl IA, ..., Fall T, Söderberg S

Circulation 138 (6) 590-599 [2018-08-07; online 2018-03-01]

Affiliated researcher

PubMed DOI Crossref

New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites.

Ballet C, Correia MSP, Conway LP, ..., Löhr JM, Globisch D

Chem Sci 9 (29) 6233-6239 [2018-08-07; online 2018-06-28]

Affiliated researcher Daniel Globisch SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Evaluation of the Therapeutic Potential of a HER3-Binding Affibody Construct TAM-HER3 in Comparison with a Monoclonal Antibody, Seribantumab.

Orlova A, Bass TZ, Rinne SS, ..., Tolmachev V, Ståhl S

Mol. Pharm. 15 (8) 3394-3403 [2018-08-06; online 2018-07-25]

Affiliated researcher

PubMed DOI Crossref

Mitochondrial genomes reveal an east to west cline of steppe ancestry in Corded Ware populations.

Juras A, Chyleński M, Ehler E, ..., Jakobsson M, Kośko A

Sci Rep 8 (1) 11603 [2018-08-02; online 2018-08-02]

Affiliated researcher

PubMed DOI Crossref

A colorimetric assay to rapidly determine the activities of lytic polysaccharide monooxygenases.

Wang D, Li J, Wong ACY, Aachmann FL, Hsieh YSY

Biotechnol Biofuels 11 (-) 215 [2018-08-02; online 2018-08-02]

Affiliated researcher

PubMed DOI Crossref

Investigation of viable taxa in the deep terrestrial biosphere suggests high rates of nutrient recycling.

Lopez-Fernandez M, Broman E, Turner S, ..., Bertilsson S, Dopson M

FEMS Microbiol. Ecol. 94 (8) - [2018-08-01; online 2018-06-23]

Affiliated researcher

PubMed DOI Crossref

Evolution of the growth hormone, prolactin, prolactin 2 and somatolactin family.

Ocampo Daza D, Larhammar D

Gen. Comp. Endocrinol. 264 (-) 94-112 [2018-08-01; online 2018-01-12]

Affiliated researcher

PubMed DOI Crossref

Different menopausal hormone regimens and risk of breast cancer.

Brusselaers N, Tamimi RM, Konings P, ..., Adami HO, Lagergren J

Ann. Oncol. 29 (8) 1771-1776 [2018-08-01; online 2018-06-20]

Affiliated researcher

PubMed DOI Crossref

CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis.

Lugano R, Vemuri K, Yu D, ..., Dejana E, Dimberg A

J. Clin. Invest. 128 (8) 3280-3297 [2018-08-01; online 2018-06-25]

Affiliated researcher

PubMed DOI Crossref

An imidazole based H-Phe-Phe-NH 2 peptidomimetic with anti-allodynic effect in spared nerve injury mice.

Skogh A, Lesniak A, Sköld C, ..., Hallberg M, Sandström A

Bioorg. Med. Chem. Lett. 28 (14) 2446-2450 [2018-08-01; online 2018-06-15]

Affiliated researcher

PubMed DOI Crossref

The environmental neurotoxin β-N-methylamino-L-alanine inhibits melatonin synthesis in primary pinealocytes and a rat model.

Pierozan P, Andersson M, Brandt I, Karlsson O

Journal of pineal research 65 (1) e12488 [2018-08-00; online 2018-04-06]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

The PDGF/PDGFR pathway as a drug target.

Papadopoulos N, Lennartsson J

Mol. Aspects Med. 62 (-) 75-88 [2018-08-00; online 2017-11-15]

Affiliated researcher

DOI Crossref

Sulfonyl Fluorides (SFs): More Than Click Reagents?

Chinthakindi PK, Arvidsson PI

Eur. J. Org. Chem. 2018 (27-28) 3648-3666 [2018-08-00; online 2018-07-06]

Affiliated researcher

PubMed DOI Crossref

Structure and function of the global topsoil microbiome.

Bahram M, Hildebrand F, Forslund SK, ..., Tedersoo L, Bork P

Nature 560 (7717) 233-237 [2018-08-00; online 2018-08-01]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Scavenging of superoxide by a membrane-bound superoxide oxidase.

Lundgren CAK, Sjöstrand D, Biner O, ..., von Ballmoos C, Högbom M

Nat. Chem. Biol. 14 (8) 788-793 [2018-08-00; online 2018-06-18]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Role of proteoglycans in neuro-inflammation and central nervous system fibrosis.

Heindryckx F, Li JP

Matrix Biol. 68-69 (-) 589-601 [2018-08-00; online 2018-01-31]

Affiliated researcher

PubMed DOI Crossref

RNA velocity of single cells.

La Manno G, Soldatov R, Zeisel A, ..., Linnarsson S, Kharchenko PV

Nature 560 (7719) 494-498 [2018-08-00; online 2018-08-08]

Affiliated researcher

PubMed DOI Crossref

Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains.

Ju CH, Blum LK, Kongpachith S, ..., Davis MM, Robinson WH

Clin. Immunol. 193 (-) 70-79 [2018-08-00; online 2018-02-02]

Affiliated researcher

PubMed DOI Crossref

Plasma Protein Profiling Reveal Osteoprotegerin as a Marker of Prognostic Impact for Colorectal Cancer.

Birgisson H, Tsimogiannis K, Freyhult E, Kamali-Moghaddam M

Transl Oncol 11 (4) 1034-1043 [2018-08-00; online 2018-07-04]

Affiliated researcher

PubMed DOI Crossref

Modulation of TGFβ/Smad signaling by the small GTPase RhoB.

Livitsanou M, Vasilaki E, Stournaras C, Kardassis D

Cell. Signal. 48 (-) 54-63 [2018-08-00; online 2018-04-26]

Affiliated researcher

PubMed DOI Crossref

Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint.

Pieper J, Dubnovitsky A, Gerstner C, ..., Achour A, Malmström V

J. Autoimmun. 92 (-) 47-56 [2018-08-00; online 2018-05-28]

Affiliated researcher

PubMed DOI Crossref

Longitudinal changes in persistent organic pollutants (POPs) from 2001 to 2009 in a sample of elderly Swedish men and women.

Stubleski J, Lind L, Salihovic S, Lind PM, Kärrman A

Environ. Res. 165 (-) 193-200 [2018-08-00; online 2018-04-30]

Affiliated researcher

DOI Crossref

Interspecific variation in ploidy as a key plant trait outlining local extinction risks and community patterns in fragmented landscapes

Plue J, Kimberley A, Slotte T

Funct Ecol 32 (8) 2095-2106 [2018-08-00; online 2018-05-22]

Affiliated researcher SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Human skin barrier structure and function analyzed by cryo-EM and molecular dynamics simulation.

Lundborg M, Narangifard A, Wennberg CL, ..., Daneholt B, Norlén L

J. Struct. Biol. 203 (2) 149-161 [2018-08-00; online 2018-04-24]

Affiliated researcher

PubMed DOI Crossref

Fast reversibly photoswitching red fluorescent proteins for live-cell RESOLFT nanoscopy.

Pennacchietti F, Serebrovskaya EO, Faro AR, ..., Mishin AS, Testa I

Nat. Methods 15 (8) 601-604 [2018-08-00; online 2018-07-09]

Affiliated researcher Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Ether cross-link formation in the R2-like ligand-binding oxidase.

Griese JJ, Branca RMM, Srinivas V, Högbom M

J. Biol. Inorg. Chem. 23 (6) 879-886 [2018-08-00; online 2018-06-26]

Affiliated researcher

PubMed DOI Crossref

Epigenetics in pediatric acute lymphoblastic leukemia.

Nordlund J, Syvänen AC

Semin. Cancer Biol. 51 (-) 129-138 [2018-08-00; online 2017-09-05]

Affiliated researcher

PubMed DOI Crossref

Epigenetics in multiple myeloma: From mechanisms to therapy.

Alzrigat M, Párraga AA, Jernberg-Wiklund H

Semin. Cancer Biol. 51 (-) 101-115 [2018-08-00; online 2017-09-27]

Affiliated researcher

PubMed DOI Crossref

Epigenetic deregulation in chronic lymphocytic leukemia: Clinical and biological impact.

Mansouri L, Wierzbinska JA, Plass C, Rosenquist R

Semin. Cancer Biol. 51 (-) 1-11 [2018-08-00; online 2018-02-07]

Affiliated researcher

PubMed DOI Crossref

Disruption of A2AR-D2R Heteroreceptor Complexes After A2AR Transmembrane 5 Peptide Administration Enhances Cocaine Self-Administration in Rats.

Borroto-Escuela DO, Wydra K, Li X, ..., Filip M, Fuxe K

Mol. Neurobiol. 55 (8) 7038-7048 [2018-08-00; online 2018-01-30]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

De novo KCNA1 variants in the PVP motif cause infantile epileptic encephalopathy and cognitive impairment similar to recurrent KCNA2 variants.

Rogers A, Golumbek P, Cellini E, ..., Thuresson AC, Gurnett CA

Am. J. Med. Genet. A 176 (8) 1748-1752 [2018-08-00; online 2018-07-28]

Affiliated researcher

PubMed DOI Crossref

DNA methylation as a genomic marker of exposure to chemical and environmental agents.

Meehan RR, Thomson JP, Lentini A, Nestor CE, Pennings S

Curr Opin Chem Biol 45 (-) 48-56 [2018-08-00; online 2018-03-02]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance.

Larsson DGJ, Andremont A, Bengtsson-Palme J, ..., Wellington EM, Wernersson AS

Environ Int 117 (-) 132-138 [2018-08-00; online 2018-05-07]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska P, Alitalo K, Allen E, ..., Yoder MC, Griffioen AW

Angiogenesis 21 (3) 425-532 [2018-08-00; online 2018-05-17]

Affiliated researcher

PubMed DOI Crossref

Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis.

Kowalec K, Wright GEB, Drögemöller BI, ..., Tremlett H, Carleton BC

Nat. Genet. 50 (8) 1081-1085 [2018-08-00; online 2018-07-16]

Affiliated researcher

PubMed DOI Crossref

Characterization of Swedish Campylobacter coli clade 2 and clade 3 water isolates.

Nilsson A, Skarp A, Johansson C, ..., Engstrand L, Rautelin H

Microbiologyopen 7 (4) e00583 [2018-08-00; online 2018-02-09]

Affiliated researcher

PubMed DOI Crossref

Changing the site energy of per-614 in the Peridinin-chlorophyll a-protein does not alter its capability of chlorophyll triplet quenching.

Agostini A, Niklas J, Schulte T, ..., Lubitz W, Carbonera D

Biochim Biophys Acta Bioenerg 1859 (8) 612-618 [2018-08-00; online 2018-05-19]

Affiliated researcher

PubMed DOI Crossref

Changes in markers of liver function in relation to changes in perfluoroalkyl substances - A longitudinal study.

Salihovic S, Stubleski J, Kärrman A, ..., Lind L, Lind PM

Environ Int 117 (-) 196-203 [2018-08-00; online 2018-05-10]

Affiliated researcher

PubMed DOI Crossref

Algorithmically probable mutations reproduce aspects of evolution, such as convergence rate, genetic memory and modularity.

Hernández-Orozco S, Kiani NA, Zenil H

R Soc Open Sci 5 (8) 180399 [2018-08-00; online 2018-08-29]

Affiliated researcher

PubMed DOI Crossref

Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans.

Cedernaes J, Schönke M, Westholm JO, ..., Zierath JR, Benedict C

Sci Adv 4 (8) eaar8590 [2018-08-00; online 2018-08-22]

Affiliated researcher

PubMed DOI Crossref

The microbial metabolite trimethylamine-N-oxide in association with inflammation and microbial dysregulation in three HIV cohorts at various disease stages.

Missailidis C, Neogi U, Stenvinkel P, ..., Nowak P, Bergman P

AIDS 32 (12) 1589-1598 [2018-07-31; online 2018-04-06]

Affiliated researcher

PubMed DOI Crossref

The Tumor Suppressor MIG6 Controls Mitotic Progression and the G2/M DNA Damage Checkpoint by Stabilizing the WEE1 Kinase.

Sasaki M, Terabayashi T, Weiss SM, Ferby I

Cell Reports 24 (5) 1278-1289 [2018-07-31; online 2018-08-02]

Affiliated researcher

PubMed DOI Crossref

RAD Sequencing and a Hybrid Antarctic Fur Seal Genome Assembly Reveal Rapidly Decaying Linkage Disequilibrium, Global Population Structure and Evidence for Inbreeding.

Humble E, Dasmahapatra KK, Martinez-Barrio A, ..., Wolf JBW, Hoffman JI

G3 8 (8) 2709-2722 [2018-07-31; online 2018-07-31]

Affiliated researcher

PubMed DOI Crossref

BARM and BalticMicrobeDB, a reference metagenome and interface to meta-omic data for the Baltic Sea.

Alneberg J, Sundh J, Bennke C, ..., Labrenz M, Andersson AF

Sci Data 5 (-) 180146 [2018-07-31; online 2018-07-31]

DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Switch-like PKA responses in the nucleus of striatal neurons.

Yapo C, Nair AG, Hellgren Kotaleski J, Vincent P, Castro LRV

J. Cell. Sci. 131 (14) - [2018-07-27; online 2018-07-27]

Affiliated researcher

PubMed DOI Crossref

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.

van Setten J, Brody JA, Jamshidi Y, ..., Arking DE, Sotoodehnia N

Nat Commun 9 (1) 2904 [2018-07-25; online 2018-07-25]

Affiliated researcher

PubMed DOI Crossref

Analysis of public RNA-sequencing data reveals biological consequences of genetic heterogeneity in cell line populations.

Fasterius E, Al-Khalili Szigyarto C

Sci Rep 8 (1) 11226 [2018-07-25; online 2018-07-25]

Affiliated researcher

PubMed DOI Crossref

A Review of Graph and Network Complexity from an Algorithmic Information Perspective.

Zenil H, Kiani NA, Tegnér J

Entropy 20 (8) 551 [2018-07-25; online 2018-07-25]

Affiliated researcher

PubMed DOI Crossref

Whole genome SNP-associated signatures of local adaptation in honeybees of the Iberian Peninsula.

Henriques D, Wallberg A, Chávez-Galarza J, ..., Webster MT, Pinto MA

Sci Rep 8 (1) 11145 [2018-07-24; online 2018-07-24]

Affiliated researcher

PubMed DOI Crossref

A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma.

Einarsdottir BO, Karlsson J, Söderberg EMV, ..., Helleday T, Nilsson JA

Cell Death Dis 9 (8) 810 [2018-07-24; online 2018-07-24]

Affiliated researcher

PubMed DOI Crossref

Targeted Repression of Essential Genes To Arrest Growth and Increase Carbon Partitioning and Biofuel Titers in Cyanobacteria.

Shabestary K, Anfelt J, Ljungqvist E, ..., Yao L, Hudson EP

ACS Synth. Biol. 7 (7) 1669-1675 [2018-07-20; online 2018-06-08]

Affiliated researcher Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

Symmetry and Correspondence of Algorithmic Complexity over Geometric, Spatial and Topological Representations

Zenil H, Kiani N, Tegnér J

Entropy 20 (7) 534 [2018-07-18; online 2018-07-18]

Affiliated researcher

PubMed DOI Crossref

Metabolic Network-Based Identification and Prioritization of Anticancer Targets Based on Expression Data in Hepatocellular Carcinoma.

Bidkhori G, Benfeitas R, Elmas E, ..., Nielsen J, Mardinoglu A

Front. Physiol. 9 (-) 916 [2018-07-17; online 2018-07-17]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome.

Sork H, Corso G, Krjutskov K, ..., Mäger I, El Andaloussi S

Sci Rep 8 (1) 10813 [2018-07-17; online 2018-07-17]

Affiliated researcher

PubMed DOI Crossref

Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events.

Honkura N, Richards M, Laviña B, ..., Betsholtz C, Claesson-Welsh L

Nat Commun 9 (1) 2746 [2018-07-16; online 2018-07-16]

Affiliated researcher

PubMed DOI Crossref

SECAPR-a bioinformatics pipeline for the rapid and user-friendly processing of targeted enriched Illumina sequences, from raw reads to alignments.

Andermann T, Cano Á, Zizka A, Bacon C, Antonelli A

PeerJ 6 (-) e5175 [2018-07-13; online 2018-07-13]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank.

Fall T, Gustafsson S, Orho-Melander M, Ingelsson E

Diabetologia - (-) - [2018-07-12; online 2018-07-12]

Affiliated researcher

PubMed DOI Crossref

Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A 2 Type X (sPLA2-X) Inhibitors.

Knerr L, Giordanetto F, Nordberg P, ..., Roth RG, Ahlqvist M

ACS Med. Chem. Lett. 9 (7) 594-599 [2018-07-12; online 2018-06-23]

Affiliated researcher

PubMed DOI Crossref

Design of Selective sPLA 2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid.

Giordanetto F, Knerr L, Nordberg P, ..., Jansen F, Ahlqvist M

ACS Med. Chem. Lett. 9 (7) 600-605 [2018-07-12; online 2018-06-23]

Affiliated researcher

PubMed DOI Crossref

Tamoxifen-Induced Apoptosis of MCF-7 Cells via GPR30/PI3K/MAPKs Interactions: Verification by ODE Modeling and RNA Sequencing.

Rouhimoghadam M, Safarian S, Carroll JS, Sheibani N, Bidkhori G

Front. Physiol. 9 (-) 907 [2018-07-11; online 2018-07-11]

Affiliated researcher

PubMed DOI Crossref

Nanoscale Spatiotemporal Diffusion Modes Measured by Simultaneous Confocal and Stimulated Emission Depletion Nanoscopy Imaging.

Schneider F, Waithe D, Galiani S, ..., Sezgin E, Eggeling C

Nano Lett. 18 (7) 4233-4240 [2018-07-11; online 2018-06-19]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Rare Copy Number Variants in Array-Based Comparative Genomic Hybridization in Early-Onset Skeletal Fragility.

Costantini A, Skarp S, Kämpe A, ..., Lindstrand A, Mäkitie O

Front Endocrinol (Lausanne) 9 (-) 380 [2018-07-10; online 2018-07-10]

Affiliated researcher

PubMed DOI Crossref

Rapid Phenotypic Antibiotic Susceptibility Testing of Uropathogens Using Optical Signal Analysis on the Nanowell Slide.

Veses-Garcia M, Antypas H, Löffler S, ..., Andersson-Svahn H, Richter-Dahlfors A

Front Microbiol 9 (-) 1530 [2018-07-10; online 2018-07-10]

Affiliated researcher

PubMed DOI Crossref

Changes in brain architecture are consistent with altered fear processing in domestic rabbits.

Brusini I, Carneiro M, Wang C, ..., Fredrikson M, Andersson L

Proc. Natl. Acad. Sci. U.S.A. 115 (28) 7380-7385 [2018-07-10; online 2018-06-25]

Affiliated researcher

PubMed DOI Crossref

Aβ under stress: the effects of acidosis, Cu 2+-binding, and oxidation on amyloid β-peptide dimers.

Liao Q, Owen MC, Bali S, Barz B, Strodel B

Chem. Commun. (Camb.) 54 (56) 7766-7769 [2018-07-10; online 2018-06-28]

Affiliated researcher

PubMed DOI Crossref

Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development.

Binder ZA, Thorne AH, Bakas S, ..., Furnari FB, O'Rourke DM

Cancer Cell 34 (1) 163-177.e7 [2018-07-09; online 2018-07-11]

Affiliated researcher

PubMed DOI Crossref

The diversity of uncharacterized antibiotic resistance genes can be predicted from known gene variants-but not always.

Bengtsson-Palme J

Microbiome 6 (1) 125 [2018-07-07; online 2018-07-07]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages.

Baskaran S, Mayrhofer M, Kultima HG, ..., Isaksson A, Nelander S

Neuro-oncology 20 (8) 1080-1091 [2018-07-05; online 2018-02-21]

Affiliated researcher

PubMed DOI Crossref

DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation.

Lemmens B, Hegarat N, Akopyan K, ..., Hochegger H, Lindqvist A

Mol. Cell 71 (1) 117-128.e3 [2018-07-05; online 2018-06-28]

Affiliated researcher

PubMed DOI Crossref

Multimodal Chemical Imaging of Amyloid Plaque Polymorphism Reveals Aβ Aggregation Dependent Anionic Lipid Accumulations and Metabolism.

Michno W, Kaya I, Nyström S, ..., Zetterberg H, Hanrieder J

Anal. Chem. 90 (13) 8130-8138 [2018-07-03; online 2018-06-19]

SciLifeLab Fellow Wojciech Michno

DOI Crossref

Morphological and genetic variation of Fucus in the eastern Gulf of Bothnia, northern Baltic Sea

Rinne H, Björkman U, Sjöqvist C, Salovius-Laurén S, Mattila J

European Journal of Phycology 53 (3) 369-380 [2018-07-03; online 2018-05-17]

Affiliated researcher

PubMed DOI Crossref

Changes in plasma levels of perfluoroalkyl substances (PFASs) are related to increase in carotid intima-media thickness over 10 years - a longitudinal study.

Lind PM, Salihovic S, Stubleski J, Kärrman A, Lind L

Environ Health 17 (1) 59 [2018-07-03; online 2018-07-03]

Affiliated researcher

PubMed DOI Crossref

3D Maps of Mineral Composition and Hydroxyapatite Orientation in Fossil Bone Samples Obtained by X-ray Diffraction Computed Tomography.

Mürer FK, Sanchez S, Álvarez-Murga M, ..., Bech M, Breiby DW

Sci Rep 8 (1) 10052 [2018-07-03; online 2018-07-03]

Affiliated researcher

PubMed DOI Crossref

Inhibition of integrin α Vβ6 changes fibril thickness of stromal collagen in experimental carcinomas.

Olof Olsson P, Gustafsson R, Salnikov AV, ..., Heldin NE, Rubin K

Cell Commun. Signal 16 (1) 36 [2018-07-02; online 2018-07-02]

Affiliated researcher

PubMed DOI Crossref

Human Immunodeficiency Virus-Infected Women Have High Numbers of CD103-CD8+ T Cells Residing Close to the Basal Membrane of the Ectocervical Epithelium.

Gibbs A, Buggert M, Edfeldt G, ..., Broliden K, Tjernlund A

J. Infect. Dis. 218 (3) 453-465 [2018-07-02; online 2017-12-23]

Affiliated researcher

PubMed DOI Crossref

EviNet: a web platform for network enrichment analysis with flexible definition of gene sets.

Jeggari A, Alekseenko Z, Petrov I, ..., Ericson J, Alexeyenko A

Nucleic Acids Res. 46 (W1) W163-W170 [2018-07-02; online 2018-06-13]

Affiliated researcher

PubMed DOI Crossref

SETD2 Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma.

Sakthikumar S, Elvers I, Kim J, ..., Marinescu VD, Lindblad-Toh K

Cancer Res. 78 (13) 3421-3431 [2018-07-01; online 2018-05-03]

Affiliated researcher

PubMed DOI Crossref

Genome Evolution of Bartonellaceae Symbionts of Ants at the Opposite Ends of the Trophic Scale.

Bisch G, Neuvonen MM, Pierce NE, ..., Lukasik P, Andersson SGE

Genome Biol Evol 10 (7) 1687-1704 [2018-07-01; online 2018-07-10]

Affiliated researcher

PubMed DOI Crossref

Formation of Immune Complexes with a Tetanus-Derived B Cell Epitope Boosts Human T Cell Responses to Covalently Linked Peptides in an Ex Vivo Blood Loop System.

Fletcher EAK, van Maren W, Cordfunke R, ..., Drijfhout JW, Mangsbo SM

J. Immunol. 201 (1) 87-97 [2018-07-01; online 2018-05-11]

Affiliated researcher

PubMed DOI Crossref

A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate.

Riley AM, Unterlass J, Konieczny V, ..., Helleday T, Potter BVL

Med. Chem. Commun. 9 (7) 1105-1113 [2018-07-01; online 2018-06-04]

Affiliated researcher

PubMed DOI Crossref

Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus.

Carlsson PO, Espes D, Sedigh A, ..., Olerud J, Korsgren O

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 18 (7) 1735-1744 [2018-07-00; online 2018-02-02]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

The vaginal microbiome amplifies sex hormone-associated cyclic changes in cervicovaginal inflammation and epithelial barrier disruption.

Bradley F, Birse K, Hasselrot K, ..., Broliden K, Burgener AD

Am. J. Reprod. Immunol. 80 (1) e12863 [2018-07-00; online 2018-04-30]

Affiliated researcher

PubMed DOI Crossref

The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock.

Garre E, Pelechano V, Sánchez Del Pino M, Alepuz P, Sunnerhagen P

PLoS Genet 14 (7) e1007563 [2018-07-00; online 2018-07-30]

Affiliated researcher SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE.

Hagberg N, Joelsson M, Leonard D, ..., Bryceson YT, Rönnblom L

Ann. Rheum. Dis. 77 (7) 1070-1077 [2018-07-00; online 2018-02-23]

Affiliated researcher

PubMed DOI Crossref

Selective concentration for ciprofloxacin resistance in Escherichia coli grown in complex aquatic bacterial biofilms.

Kraupner N, Ebmeyer S, Bengtsson-Palme J, ..., Flach CF, Larsson DGJ

Environ Int 116 (-) 255-268 [2018-07-00; online 2018-04-25]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Oak genome reveals facets of long lifespan.

Plomion C, Aury JM, Amselem J, ..., Kremer A, Salse J

Nat Plants 4 (7) 440-452 [2018-07-00; online 2018-06-18]

Affiliated researcher

PubMed DOI Crossref

Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis.

Leonard D, Svenungsson E, Dahlqvist J, ..., Criswell LA, Rönnblom L

Ann. Rheum. Dis. 77 (7) 1063-1069 [2018-07-00; online 2018-03-07]

Affiliated researcher

PubMed DOI Crossref

Molecular allergen profiling in horses by microarray reveals Fag e 2 from buckwheat as a frequent sensitizer.

Einhorn L, Hofstetter G, Brandt S, ..., Pali-Schöll I, Jensen-Jarolim E

Allergy 73 (7) 1436-1446 [2018-07-00; online 2018-02-27]

Affiliated researcher

PubMed DOI Crossref

Mining the Human Tissue Proteome for Protein Citrullination.

Lee CY, Wang D, Wilhelm M, ..., Hahne H, Kuster B

Mol. Cell Proteomics 17 (7) 1378-1391 [2018-07-00; online 2018-04-02]

Affiliated researcher

DOI Crossref

Intra-droplet acoustic particle focusing: simulations and experimental observations

Fornell A, Garofalo F, Nilsson J, Bruus H, Tenje M

Microfluid Nanofluid 22 (7) - [2018-07-00; online 2018-06-28]

Affiliated researcher

PubMed DOI Crossref

Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling.

Hertzog J, Dias Junior AG, Rigby RE, ..., Kohl A, Rehwinkel J

Eur. J. Immunol. 48 (7) 1120-1136 [2018-07-00; online 2018-04-06]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML.

Brück O, Blom S, Dufva O, ..., Pellinen T, Mustjoki S

Leukemia 32 (7) 1643-1656 [2018-07-00; online 2018-06-20]

Affiliated researcher

PubMed DOI Crossref

Identification of inhibitors of Tartrate-resistant acid phosphatase (TRAP/ACP5) activity by small-molecule screening.

Reithmeier A, Lundbäck T, Haraldsson M, ..., Gustavsson AL, Andersson G

Chem Biol Drug Des 92 (1) 1255-1271 [2018-07-00; online 2018-03-30]

Affiliated researcher

PubMed DOI Crossref

High speed of fork progression induces DNA replication stress and genomic instability.

Maya-Mendoza A, Moudry P, Merchut-Maya JM, ..., Strauss R, Bartek J

Nature 559 (7713) 279-284 [2018-07-00; online 2018-06-27]

Affiliated researcher

DOI Crossref

Genome-wide expression analysis suggests a role for jasmonates in the resistance to blue mold in apple

Ahmadi-Afzadi M, Orsel M, Pelletier S, ..., Nybom H, Renou JP

Plant Growth Regul 85 (3) 375-387 [2018-07-00; online 2018-04-18]

Affiliated researcher

PubMed DOI Crossref

Four evolutionary trajectories underlie genetic intratumoral variation in childhood cancer.

Karlsson J, Valind A, Holmquist Mengelbier L, ..., Bexell D, Gisselsson D

Nat. Genet. 50 (7) 944-950 [2018-07-00; online 2018-06-04]

Affiliated researcher

PubMed DOI Crossref

Demographic expansion and genetic load of the halophyte model plant Eutrema salsugineum.

Wang XJ, Hu QJ, Guo XY, ..., Lascoux M, Liu JQ

Mol. Ecol. 27 (14) 2943-2955 [2018-07-00; online 2018-06-22]

Affiliated researcher

PubMed DOI Crossref

Childhood Bereavement and Lower Stress Resilience in Late Adolescence.

Kennedy B, Chen R, Valdimarsdóttir U, ..., Fang F, Fall K

J Adolesc Health 63 (1) 108-114 [2018-07-00; online 2018-04-30]

Affiliated researcher

PubMed DOI Crossref

Cannabinoid Type 1 Receptors Are Upregulated During Acute Activation of Brown Adipose Tissue.

Lahesmaa M, Eriksson O, Gnad T, ..., Virtanen KA, Nuutila P

Diabetes 67 (7) 1226-1236 [2018-07-00; online 2018-04-12]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Associations of monoamine oxidase A gene first exon methylation with sexual abuse and current depression in women.

Checknita D, Ekström TJ, Comasco E, ..., Tiihonen J, Hodgins S

J Neural Transm (Vienna) 125 (7) 1053-1064 [2018-07-00; online 2018-03-29]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Assessing uncertainties in x-ray single-particle three-dimensional reconstruction.

Liu J, Engblom S, Nettelblad C

Phys Rev E 98 (1-1) 013303 [2018-07-00; online 2018-08-17]

Affiliated researcher

PubMed DOI Crossref

An in vitro model of lissencephaly: expanding the role of DCX during neurogenesis.

Shahsavani M, Pronk RJ, Falk R, ..., Gage FH, Falk A

Mol. Psychiatry 23 (7) 1674-1684 [2018-07-00; online 2017-09-19]

Affiliated researcher

PubMed DOI Crossref

ADARs and editing: The role of A-to-I RNA modification in cancer progression.

Fritzell K, Xu LD, Lagergren J, Öhman M

Semin. Cell Dev. Biol. 79 (-) 123-130 [2018-07-00; online 2017-11-16]

Affiliated researcher

PubMed DOI Crossref

A reassessment of DNA-immunoprecipitation-based genomic profiling.

Lentini A, Lagerwall C, Vikingsson S, ..., Benson M, Nestor CE

Nat. Methods 15 (7) 499-504 [2018-07-00; online 2018-06-25]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

A protein activity assay to measure global transcription factor activity reveals determinants of chromatin accessibility.

Wei B, Jolma A, Sahu B, ..., Taipale M, Taipale J

Nat. Biotechnol. 36 (6) 521-529 [2018-07-00; online 2018-05-21]

Affiliated researcher

DOI Crossref

Multidimensional transcriptomics provides detailed information about immune cell distribution and identity in HER2+ breast tumors

Salmén F, Vickovic S, Larsson L, ..., Ståhl PL, Lundeberg J

- - (-) - [2018-06-29; online 2018-06-29]

Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

Docking Screens for Dual Inhibitors of Disparate Drug Targets for Parkinson's Disease.

Jaiteh M, Zeifman A, Saarinen M, ..., Loza MI, Carlsson J

J Med Chem 61 (12) 5269-5278 [2018-06-28; online 2018-06-15]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Phenotypic Image Analysis Software Tools for Exploring and Understanding Big Image Data from Cell-Based Assays.

Smith K, Piccinini F, Balassa T, ..., Azizpour H, Horvath P

Cell Systems 6 (6) 636-653 [2018-06-27; online 2018-06-29]

Affiliated researcher

PubMed DOI Crossref

Model Communities Hint at Promiscuous Metabolic Linkages between Ubiquitous Free-Living Freshwater Bacteria.

Garcia SL, Buck M, Hamilton JJ, ..., McMahon KD, Eiler A

mSphere 3 (3) - [2018-06-27; online 2018-05-30]

Affiliated researcher Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

A reference cytochrome c oxidase subunit I database curated for hierarchical classification of arthropod metabarcoding data

Richardson RT, Bengtsson-Palme J, Gardiner MM, Johnson RM

PeerJ 6 (-) e5126 [2018-06-26; online 2018-06-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Understanding the Representative Gut Microbiota Dysbiosis in Metformin-Treated Type 2 Diabetes Patients Using Genome-Scale Metabolic Modeling.

Rosario D, Benfeitas R, Bidkhori G, ..., Shoaie S, Mardinoglu A

Front. Physiol. 9 (-) 775 [2018-06-25; online 2018-06-25]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy.

Vorobyeva A, Westerlund K, Mitran B, ..., Tolmachev V, Karlström AE

Sci Rep 8 (1) 9643 [2018-06-25; online 2018-06-25]

Affiliated researcher

PubMed DOI Crossref

Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4.

Søndergaard JN, van Heeringen SJ, Looman MWG, ..., Ansems M, Adema GJ

Front Immunol 9 (-) 1420 [2018-06-22; online 2018-06-22]

Affiliated researcher

PubMed DOI Crossref

In Vitro Evolution of Antibodies Inspired by In Vivo Evolution.

Persson H, Kirik U, Thörnqvist L, ..., Levander F, Ohlin M

Front Immunol 9 (-) 1391 [2018-06-21; online 2018-06-21]

Affiliated researcher

PubMed DOI Crossref

Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity.

Berglund E, Maaskola J, Schultz N, ..., Helleday T, Lundeberg J

Nat Commun 9 (1) 2419 [2018-06-20; online 2018-06-20]

Affiliated researcher Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

Protein Evolution and Design.

von Heijne G

Annu. Rev. Biochem. 87 (-) 101-103 [2018-06-20; online 2018-06-22]

Affiliated researcher

PubMed DOI Crossref

Global time trends in the incidence of esophageal squamous cell carcinoma.

Wang QL, Xie SH, Wahlin K, Lagergren J

Clin Epidemiol 10 (-) 717-728 [2018-06-19; online 2018-06-19]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

Gene expression profiling of periodontitis-affected gingival tissue by spatial transcriptomics.

Lundmark A, Gerasimcik N, Båge T, ..., Lundeberg J, Yucel-Lindberg T

Sci Rep 8 (1) 9370 [2018-06-19; online 2018-06-19]

Affiliated researcher

PubMed DOI Crossref

Poly(alkylidenimine) Dendrimers Functionalized with the Organometallic Moiety [Ru(η⁵-C₅H₅)(PPh₃)₂]⁺ as Promising Drugs Against Cisplatin-Resistant Cancer Cells and Human Mesenchymal Stem Cells.

Gouveia M, Figueira J, Jardim MG, ..., Rissanen K, Rodrigues J

Molecules 23 (6) - [2018-06-17; online 2018-06-17]

Affiliated researcher

PubMed DOI Crossref

eIF4E-Binding Proteins 1 and 2 Limit Macrophage Anti-Inflammatory Responses through Translational Repression of IL-10 and Cyclooxygenase-2.

William M, Leroux LP, Chaparro V, ..., Larsson O, Jaramillo M

J. Immunol. 200 (12) 4102-4116 [2018-06-15; online 2018-04-30]

Affiliated researcher

PubMed DOI Crossref

Stabilized Cyclic Peptides as Scavengers of Autoantibodies: Neutralization of Anticitrullinated Protein/Peptide Antibodies in Rheumatoid Arthritis.

Gunasekera S, Fernandes-Cerqueira C, Wennmalm S, ..., Jakobsson PJ, Göransson U

ACS Chem. Biol. 13 (6) 1525-1535 [2018-06-15; online 2018-05-24]

Affiliated researcher

PubMed DOI Crossref

Extracellular nanovesicles released from the commensal yeast Malassezia sympodialis are enriched in allergens and interact with cells in human skin.

Johansson HJ, Vallhov H, Holm T, ..., Lehtiö J, Scheynius A

Sci Rep 8 (1) 9182 [2018-06-15; online 2018-06-15]

Affiliated researcher

PubMed DOI Crossref

User-Friendly Genetic Conditional Knockout Strategies by CRISPR/Cas9.

Chen L, Ye Y, Dai H, ..., Ren W, Zhang W

Stem Cells Int 2018 (-) 9576959 [2018-06-14; online 2018-06-14]

Affiliated researcher

PubMed DOI Crossref

Complementary studies of lipid membrane dynamics using iSCAT and super-resolved fluorescence correlation spectroscopy.

Reina F, Galiani S, Shrestha D, ..., Kukura P, Eggeling C

J. Phys. D: Appl. Phys. 51 (23) 235401 [2018-06-13; online 2018-05-16]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Antischistosomal Properties of Hederacolchiside A1 Isolated from Pulsatilla chinensis.

Kang N, Shen W, Gao H, ..., Xu Q, Yu D

Molecules 23 (6) - [2018-06-13; online 2018-06-13]

Affiliated researcher

PubMed DOI Crossref

Investigating Holocene human population history in North Asia using ancient mitogenomes.

Kılınç GM, Kashuba N, Yaka R, ..., Storå J, Götherström A

Sci Rep 8 (1) 8969 [2018-06-12; online 2018-06-12]

Affiliated researcher

PubMed DOI Crossref

Associations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease: Longitudinal Analyses in the UK Biobank Study.

Tikkanen E, Gustafsson S, Ingelsson E

Circulation 137 (24) 2583-2591 [2018-06-12; online 2018-04-09]

Affiliated researcher

PubMed DOI Crossref

A universal platform for selection and high-resolution phenotypic screening of bacterial mutants using the nanowell slide.

Antypas H, Veses-Garcia M, Weibull E, Andersson-Svahn H, Richter-Dahlfors A

Lab Chip 18 (12) 1767-1777 [2018-06-12; online 2018-05-22]

Affiliated researcher

PubMed DOI Crossref

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

Gogola E, Duarte AA, de Ruiter JR, ..., Jonkers J, Rottenberg S

Cancer Cell 33 (6) 1078-1093.e12 [2018-06-11; online 2018-06-13]

Affiliated researcher

PubMed DOI Crossref

Whole Exome Sequencing of Patients from Multicase Families with Systemic Lupus Erythematosus Identifies Multiple Rare Variants.

Delgado-Vega AM, Martínez-Bueno M, Oparina NY, ..., Kozyrev SV, Alarcón-Riquelme ME

Sci Rep 8 (1) 8775 [2018-06-08; online 2018-06-08]

Affiliated researcher

PubMed DOI Crossref

An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.

Keedy DA, Hill ZB, Biel JT, ..., Wells JA, Fraser JS

Elife 7 (-) - [2018-06-07; online 2018-06-07]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance.

Nowak C, Hetty S, Salihovic S, ..., Fall T, Ingelsson E

Sci Rep 8 (1) 8691 [2018-06-06; online 2018-06-06]

Affiliated researcher

PubMed DOI Crossref

Mitochondrial Translation Efficiency Controls Cytoplasmic Protein Homeostasis.

Suhm T, Kaimal JM, Dawitz H, ..., Andréasson C, Ott M

Cell Metab. 27 (6) 1309-1322.e6 [2018-06-05; online 2018-05-10]

Affiliated researcher

PubMed DOI Crossref

Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids.

Treyer A, Mateus A, Wiśniewski JR, ..., Matsson P, Artursson P

Mol. Pharm. 15 (6) 2224-2233 [2018-06-04; online 2018-05-11]

Affiliated researcher

PubMed DOI Crossref

Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions.

Spiess M, Hernandez-Varas P, Oddone A, ..., Lakadamyali M, Strömblad S

J. Cell Biol. 217 (6) 1929-1940 [2018-06-04; online 2018-04-09]

Affiliated researcher

PubMed DOI Crossref

A major locus controls local adaptation and adaptive life history variation in a perennial plant.

Wang J, Ding J, Tan B, ..., Street NR, Ingvarsson PK

Genome Biol. 19 (1) 72 [2018-06-04; online 2018-06-04]

Affiliated researcher

PubMed DOI Crossref

Testis transcriptome alterations in zebrafish (Danio rerio) with reduced fertility due to developmental exposure to 17α-ethinyl estradiol.

Porseryd T, Reyhanian Caspillo N, Volkova K, ..., Olsson PE, Porsch-Hällström I

Gen. Comp. Endocrinol. 262 (-) 44-58 [2018-06-01; online 2018-03-08]

Affiliated researcher

PubMed DOI Crossref

Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI.

Kipper K, Eremina N, Marklund E, ..., Elf J, Deindl S

PLoS ONE 13 (6) e0198416 [2018-06-01; online 2018-06-01]

Affiliated researcher Emil Marklund SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

ST Spot Detector: a web-based application for automatic spot and tissue detection for spatial Transcriptomics image datasets.

Wong K, Navarro JF, Bergenstråhle L, Ståhl PL, Lundeberg J

Bioinformatics 34 (11) 1966-1968 [2018-06-01; online 2018-01-24]

Affiliated researcher

PubMed DOI Crossref

Presence of Aedes and Anopheles mosquito larvae is correlated to bacteria found in domestic water-storage containers.

Nilsson LKJ, Sharma A, Bhatnagar RK, Bertilsson S, Terenius O

FEMS Microbiol. Ecol. 94 (6) - [2018-06-01; online 2018-04-05]

Affiliated researcher

PubMed DOI Crossref

Influence of Na+ and Mg2+ ions on RNA structures studied with molecular dynamics simulations.

Fischer NM, Polêto MD, Steuer J, van der Spoel D

Nucleic Acids Res. 46 (10) 4872-4882 [2018-06-01; online 2018-05-03]

Affiliated researcher

PubMed DOI Crossref

Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium.

Nicholson AM, Olpe C, Hoyle A, ..., Morrissey E, Winton DJ

Cell Stem Cell 22 (6) 909-918.e8 [2018-06-01; online 2018-05-17]

Affiliated researcher

PubMed DOI Crossref

Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION.

Nakane T, Kimanius D, Lindahl E, Scheres SH

Elife 7 (-) - [2018-06-01; online 2018-06-01]

Affiliated researcher

PubMed DOI Crossref

A vertical flow paper-microarray assay with isothermal DNA amplification for detection of Neisseria meningitidis.

Rivas L, Reuterswärd P, Rasti R, ..., Gantelius J, Andersson-Svahn H

Talanta 183 (-) 192-200 [2018-06-01; online 2018-02-16]

Affiliated researcher

PubMed DOI Crossref

γ-glutamyl transpeptidase deficiency caused by a large homozygous intragenic deletion in GGT1.

Darin N, Leckström K, Sikora P, ..., Almén G, Asin-Cayuela J

Eur. J. Hum. Genet. 26 (6) 808-817 [2018-06-00; online 2018-02-26]

Affiliated researcher

PubMed DOI Crossref

Topology of membrane proteins-predictions, limitations and variations.

Tsirigos KD, Govindarajan S, Bassot C, ..., Shu N, Elofsson A

Curr. Opin. Struct. Biol. 50 (-) 9-17 [2018-06-00; online 2017-11-05]

Affiliated researcher

PubMed DOI Crossref

T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus.

Houtman M, Shchetynsky K, Chemin K, ..., Malmström V, Padyukov L

J. Autoimmun. 90 (-) 28-38 [2018-06-00; online 2018-02-03]

Affiliated researcher

PubMed DOI Crossref

Systems biology in hepatology: approaches and applications.

Mardinoglu A, Boren J, Smith U, Uhlen M, Nielsen J

Nat Rev Gastroenterol Hepatol 15 (6) 365-377 [2018-06-00; online 2018-04-25]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Specificity of glycosaminoglycan-protein interactions.

Kjellén L, Lindahl U

Curr. Opin. Struct. Biol. 50 (-) 101-108 [2018-06-00; online 2018-02-09]

Affiliated researcher

PubMed DOI Crossref

Paternally expressed imprinted genes associate with hybridization barriers in Capsella.

Lafon-Placette C, Hatorangan MR, Steige KA, ..., Slotte T, Köhler C

Nat Plants 4 (6) 352-357 [2018-06-00; online 2018-05-28]

Affiliated researcher SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Novel variants in Nordic patients referred for genetic testing of telomere-related disorders.

Norberg A, Rosén A, Raaschou-Jensen K, ..., Degerman S, Hultdin M

Eur. J. Hum. Genet. 26 (6) 858-867 [2018-06-00; online 2018-02-26]

Affiliated researcher

PubMed DOI Crossref

Molecular mechanisms driving transcriptional stress responses.

Vihervaara A, Duarte FM, Lis JT

Nat. Rev. Genet. 19 (6) 385-397 [2018-06-00; online 2018-03-21]

Anniina Vihervaara SciLifeLab Fellow

PubMed DOI Crossref

Metabolite Depletion Affects Flux Profiling of Cell Lines.

Nilsson A, Haanstra JR, Teusink B, Nielsen J

Trends Biochem. Sci. 43 (6) 395-397 [2018-06-00; online 2018-04-12]

Avlant Nilsson DDLS Fellow

DOI Crossref

Increasing dominance of terrigenous organic matter in circumpolar freshwaters due to permafrost thaw

Wauthy M, Rautio M, Christoffersen KS, ..., Peura S, Vincent WF

Limnol. Oceanogr. 3 (3) 186-198 [2018-06-00; online 2018-02-01]

Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

Improved protein model quality assessments by changing the target function.

Uziela K, Menéndez Hurtado D, Shu N, Wallner B, Elofsson A

Proteins 86 (6) 654-663 [2018-06-00; online 2018-04-15]

Affiliated researcher

PubMed DOI Crossref

Genomewide binding of transcription factor Snail1 in triple-negative breast cancer cells.

Maturi V, Morén A, Enroth S, Heldin CH, Moustakas A

Mol Oncol 12 (7) 1153-1174 [2018-06-00; online 2018-05-21]

Affiliated researcher

PubMed DOI Crossref

Exploring the Viral Channel KcvPBCV-1 Function via Computation.

Andersson AEV, Kasimova MA, Delemotte L

J. Membr. Biol. 251 (3) 419-430 [2018-06-00; online 2018-02-23]

Affiliated researcher Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Elevated inflammation in association with alcohol abuse among Blacks but not Whites: results from the MIDUS biomarker study.

Ransome Y, Slopen N, Karlsson O, Williams DR

J Behav Med 41 (3) 374-384 [2018-06-00; online 2017-12-11]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

Diminished CXCR5 expression in peripheral blood of patients with Sjögren's syndrome may relate to both genotype and salivary gland homing.

Aqrawi LA, Ivanchenko M, Björk A, ..., Skarstein K, Wahren-Herlenius M

Clin. Exp. Immunol. 192 (3) 259-270 [2018-06-00; online 2018-03-24]

Affiliated researcher

PubMed DOI Crossref

Circulating levels of perfluoroalkyl substances and left ventricular geometry of the heart in the elderly.

Mobacke I, Lind L, Dunder L, Salihovic S, Lind PM

Environ Int 115 (-) 295-300 [2018-06-00; online 2018-04-03]

Affiliated researcher

PubMed DOI Crossref

Bioengineering with Endothelial Progenitor Cells Improves the Vascular Engraftment of Transplanted Human Islets.

Grapensparr L, Christoffersson G, Carlsson PO

Cell Transplant 27 (6) 948-956 [2018-06-00; online 2018-06-03]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

A novel ECEL1 mutation expands the phenotype of distal arthrogryposis multiplex congenita type 5D to include pretibial vertical skin creases.

Stattin EL, Johansson J, Gudmundsson S, ..., Bondeson ML, Wilbe M

Am. J. Med. Genet. A 176 (6) 1405-1410 [2018-06-00; online 2018-04-16]

Affiliated researcher

DOI Crossref

Gammaproteobacterial methanotrophs dominate methanotrophy in aerobic and anaerobic layers of boreal lake waters

Rissanen A, Saarenheimo J, Tiirola M, ..., Karvinen A, Nykänen H

Aquat. Microb. Ecol. 81 (3) 257-276 [2018-05-30; online 2018-05-30]

Affiliated researcher Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison's disease in Sweden.

Eriksson D, Bianchi M, Landegren N, ..., Rosengren Pielberg G, Kämpe O

Sci Rep 8 (1) 8395 [2018-05-30; online 2018-05-30]

Affiliated researcher

PubMed DOI Crossref

Force Field Benchmark of Amino Acids: I. Hydration and Diffusion in Different Water Models.

Zhang H, Yin C, Jiang Y, van der Spoel D

J Chem Inf Model 58 (5) 1037-1052 [2018-05-29; online 2018-04-18]

Affiliated researcher

PubMed DOI Crossref

Emulsions Stabilized by Chitosan-Modified Silica Nanoparticles: pH Control of Structure-Property Relations.

Alison L, Demirörs AF, Tervoort E, ..., Vermant J, Studart AR

Langmuir 34 (21) 6147-6160 [2018-05-29; online 2018-05-17]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

Network Visualization and Analysis of Spatially Aware Gene Expression Data with InsituNet.

Salamon J, Qian X, Nilsson M, Lynn DJ

Cell Systems 6 (5) 626-630.e3 [2018-05-23; online 2018-05-09]

Affiliated researcher

PubMed DOI Crossref

Thermophoresis-Controlled Size-Dependent DNA Translocation through an Array of Nanopores.

Zhang M, Ngampeerapong C, Redin D, ..., Sychugov I, Linnros J

ACS Nano 12 (5) 4574-4582 [2018-05-22; online 2018-04-19]

Affiliated researcher

PubMed DOI Crossref

Systematic approach for dissecting the molecular mechanisms of transcriptional regulation in bacteria.

Belliveau NM, Barnes SL, Ireland WT, ..., Kinney JB, Phillips R

Proc. Natl. Acad. Sci. U.S.A. 115 (21) E4796-E4805 [2018-05-22; online 2018-05-04]

Affiliated researcher

PubMed DOI Crossref

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S

Nat Commun 9 (1) 2071 [2018-05-22; online 2018-05-22]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery.

Simm J, Klambauer G, Arany A, ..., Moreau Y, Ceulemans H

Cell Chem Biol 25 (5) 611-618.e3 [2018-05-17; online 2018-03-01]

Affiliated researcher

PubMed DOI Crossref

Aggregated Aβ1-42 Is Selectively Toxic for Neurons, Whereas Glial Cells Produce Mature Fibrils with Low Toxicity in Drosophila.

Jonson M, Nyström S, Sandberg A, ..., Thor S, Hammarström P

Cell Chem Biol 25 (5) 595-610.e5 [2018-05-17; online 2018-04-12]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Quantitation of Endogenous Metabolites in Mouse Tumors Using Mass-Spectrometry Imaging.

Swales JG, Dexter A, Hamm G, ..., Critchlow SE, Goodwin RJA

Anal. Chem. 90 (10) 6051-6058 [2018-05-15; online 2018-04-26]

Affiliated researcher

PubMed DOI Crossref

Nontarget Mass Spectrometry Reveals New Perfluoroalkyl Substances in Fish from the Yangtze River and Tangxun Lake, China.

Liu Y, Qian M, Ma X, Zhu L, Martin JW

Environ. Sci. Technol. 52 (10) 5830-5840 [2018-05-15; online 2018-04-27]

Affiliated researcher

PubMed DOI Crossref

Human skin barrier formation takes place via a cubic to lamellar lipid phase transition as analyzed by cryo-electron microscopy and EM-simulation.

Narangifard A, den Hollander L, Wennberg CL, ..., Daneholt B, Norlén L

Exp. Cell Res. 366 (2) 139-151 [2018-05-15; online 2018-03-19]

Affiliated researcher

PubMed DOI Crossref

Drug Repositioning for Effective Prostate Cancer Treatment.

Turanli B, Grøtli M, Boren J, ..., Arga KY, Mardinoglu A

Front. Physiol. 9 (-) 500 [2018-05-15; online 2018-05-15]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia.

Chen X, Gustafsson S, Whitington T, ..., Frostegård J, Magnusson PKE

Hum. Mol. Genet. 27 (10) 1809-1818 [2018-05-15; online 2018-03-17]

Affiliated researcher

PubMed DOI Crossref

Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants.

Zhou A, Taylor AE, Karhunen V, ..., Llewellyn DJ, Hyppönen E

Sci Rep 8 (1) 7526 [2018-05-14; online 2018-05-14]

Affiliated researcher

PubMed DOI Crossref

Competitive ability of Capsella species with different mating systems and ploidy levels.

Petrone Mendoza S, Lascoux M, Glémin S

Ann. Bot. 121 (6) 1257-1264 [2018-05-11; online 2018-02-23]

Affiliated researcher

PubMed DOI Crossref

Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5.

Rossi Sebastiano M, Doak BC, Backlund M, ..., Matsson P, Kihlberg J

J. Med. Chem. 61 (9) 4189-4202 [2018-05-10; online 2018-04-16]

Affiliated researcher

PubMed DOI Crossref

Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology.

Liljeruhm J, Funk SK, Tietscher S, ..., Wistrand-Yuen E, Forster AC

J Biol Eng 12 (-) 8 [2018-05-10; online 2018-05-10]

Affiliated researcher

PubMed DOI Crossref

Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3.

Schmidt A, Marabita F, Kiani NA, ..., Lahesmaa R, Tegnér J

BMC Biol. 16 (1) 47 [2018-05-07; online 2018-05-07]

Affiliated researcher

PubMed DOI Crossref

PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1.

Papadopoulos N, Lennartsson J, Heldin CH

J. Cell Biol. 217 (5) 1701-1717 [2018-05-07; online 2018-03-15]

Affiliated researcher

PubMed DOI Crossref

Response to "Comparison and Evaluation of Clustering Algorithms for Tandem Mass Spectra".

Griss J, Perez-Riverol Y, The M, Käll L, Vizcaíno JA

J. Proteome Res. 17 (5) 1993-1996 [2018-05-04; online 2018-04-25]

Affiliated researcher

PubMed DOI Crossref

A Protein Standard That Emulates Homology for the Characterization of Protein Inference Algorithms.

The M, Edfors F, Perez-Riverol Y, ..., Forsström B, Käll L

J. Proteome Res. 17 (5) 1879-1886 [2018-05-04; online 2018-04-16]

Affiliated researcher

PubMed DOI Crossref

Unique Phenotypic Characteristics of Recently Transmitted HIV-1 Subtype C Envelope Glycoprotein gp120: Use of CXCR6 Coreceptor by Transmitted Founder Viruses.

Ashokkumar M, Aralaguppe SG, Tripathy SP, Hanna LE, Neogi U

J. Virol. 92 (9) - [2018-05-01; online 2018-04-13]

Affiliated researcher

PubMed DOI Crossref

Tracking the NGS revolution: managing life science research on shared high-performance computing clusters.

Dahlö M, Scofield DG, Schaal W, Spjuth O

Gigascience 7 (5) - [2018-05-01; online 2018-04-17]

Affiliated researcher

PubMed DOI Crossref

Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site.

Wahlgren WY, Dunevall E, North RA, ..., Ramaswamy S, Friemann R

Nat Commun 9 (1) 1753 [2018-05-01; online 2018-05-01]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Potentials and pitfalls of inverse fluorescence correlation spectroscopy.

Wennmalm S

Methods 140-141 (-) 23-31 [2018-05-01; online 2018-02-02]

Affiliated researcher

PubMed DOI Crossref

Placental lncRNA Expression Is Associated With Prenatal Phthalate Exposure.

Machtinger R, Zhong J, Mansur A, ..., Karlsson O, Baccarelli AA

Toxicol Sci 163 (1) 116-122 [2018-05-01; online 2018-02-01]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

Overexpression of heparanase in mice promoted megakaryopoiesis.

Tan YX, Cui H, Wan LM, ..., Vlodavsky I, Li JP

Glycobiology 28 (5) 269-275 [2018-05-01; online 2018-02-23]

Affiliated researcher

PubMed DOI Crossref

MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma.

Zingoni A, Vulpis E, Cecere F, ..., Cerboni C, Santoni A

Front Immunol 9 (-) 926 [2018-05-01; online 2018-05-01]

Affiliated researcher

PubMed DOI Crossref

Integrin α

Lidén Å, Karlsen TV, Guss B, Reed RK, Rubin K

Exp. Physiol. 103 (5) 629-634 [2018-05-01; online 2018-03-11]

Affiliated researcher

PubMed DOI Crossref

Estimating Age-Dependent Extinction: Contrasting Evidence from Fossils and Phylogenies.

Hagen O, Andermann T, Quental TB, Antonelli A, Silvestro D

Syst. Biol. 67 (3) 458-474 [2018-05-01; online 2017-10-27]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

Epoxide hydrolysis as a model system for understanding flux through a branched reaction scheme.

Janfalk Carlsson Å, Bauer P, Dobritzsch D, Kamerlin SCL, Widersten M

IUCrJ 5 (Pt 3) 269-282 [2018-05-01; online 2018-03-22]

Affiliated researcher

PubMed DOI Crossref

Array profiling reveals contribution of Cthrc1 to growth of the denervated rat urinary bladder.

Zhu B, Ekman M, Svensson D, ..., Uvelius B, Swärd K

Am. J. Physiol. Renal Physiol. 314 (5) F893-F905 [2018-05-01; online 2018-01-10]

Affiliated researcher

PubMed DOI Crossref

Transcription profiling of peripheral B cells in antibody-positive primary Sjögren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature.

Imgenberg-Kreuz J, Sandling JK, Björk A, ..., Syvänen AC, Nordmark G

Scand. J. Immunol. 87 (5) e12662 [2018-05-00; online 2018-04-15]

Affiliated researcher

PubMed DOI Crossref

Sulfasalazine-Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus.

Wadelius M, Eriksson N, Kreutz R, ..., Hallberg P, EuDAC

Clin. Pharmacol. Ther. 103 (5) 843-853 [2018-05-00; online 2017-09-28]

Affiliated researcher

PubMed DOI Crossref

Snail regulates BMP and TGFβ pathways to control the differentiation status of glioma-initiating cells.

Caja L, Tzavlaki K, Dadras MS, ..., Heldin CH, Moustakas A

Oncogene 37 (19) 2515-2531 [2018-05-00; online 2018-02-16]

Affiliated researcher

PubMed DOI Crossref

Snail mediates crosstalk between TGFβ and LXRα in hepatocellular carcinoma.

Bellomo C, Caja L, Fabregat I, ..., Heldin CH, Moustakas A

Cell Death Differ. 25 (5) 885-903 [2018-05-00; online 2017-12-11]

Affiliated researcher

PubMed DOI Crossref

Prostaglandin E

Maric J, Ravindran A, Mazzurana L, ..., Konya V, Mjösberg J

J. Allergy Clin. Immunol. 141 (5) 1761-1773.e6 [2018-05-00; online 2017-12-05]

Affiliated researcher

PubMed DOI Crossref

Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells.

Pierozan P, Jerneren F, Karlsson O

Arch. Toxicol. 92 (5) 1729-1739 [2018-05-00; online 2018-03-03]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

Hyperglycemia Alters Expression of Cerebral Metabolic Genes after Cardiac Arrest.

Lindblom RPF, Molnar M, Israelsson C, ..., Wiklund L, Lennmyr F

J Stroke Cerebrovasc Dis 27 (5) 1200-1211 [2018-05-00; online 2018-01-03]

Affiliated researcher

PubMed DOI Crossref

Agathangelidis A, Ljungström V, Scarfò L, ..., Rosenquist R, Ghia P

Haematologica 103 (5) 865-873 [2018-05-00; online 2018-02-15]

Affiliated researcher

PubMed DOI Crossref

ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation.

Malcikova J, Tausch E, Rossi D, ..., Pospisilova S, European Research Initiative on Chronic Lymphocytic Leukemia (ERIC) — TP53 network

Leukemia 32 (5) 1070-1080 [2018-05-00; online 2018-02-02]

Affiliated researcher

PubMed DOI Crossref

Differential susceptibility effects of oxytocin gene (OXT) polymorphisms and perceived parenting on social anxiety among adolescents.

Olofsdotter S, Åslund C, Furmark T, Comasco E, Nilsson KW

Dev Psychopathol 30 (2) 449-459 [2018-05-00; online 2017-06-13]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Detecting ligand interactions in real time on living bacterial cells.

Encarnação JC, Schulte T, Achour A, Björkelund H, Andersson K

Appl. Microbiol. Biotechnol. 102 (9) 4193-4201 [2018-05-00; online 2018-03-17]

Affiliated researcher

PubMed DOI Crossref

Demystifying Eukaryote Lateral Gene Transfer (Response to Martin 2017 DOI: 10.1002/bies.201700115).

Leger MM, Eme L, Stairs CW, Roger AJ

Bioessays 40 (5) e1700242 [2018-05-00; online 2018-03-15]

Affiliated researcher

PubMed DOI Crossref

Deep mitochondrial origin outside the sampled alphaproteobacteria.

Martijn J, Vosseberg J, Guy L, Offre P, Ettema TJG

Nature 557 (7703) 101-105 [2018-05-00; online 2018-04-25]

Affiliated researcher

PubMed DOI Crossref

DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus.

Imgenberg-Kreuz J, Carlsson Almlöf J, Leonard D, ..., Syvänen AC, Sandling JK

Ann. Rheum. Dis. 77 (5) 736-743 [2018-05-00; online 2018-02-01]

Affiliated researcher

PubMed DOI Crossref

Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma.

Bolin S, Borgenvik A, Persson CU, ..., Weishaupt H, Swartling FJ

Oncogene 37 (21) 2850-2862 [2018-05-00; online 2018-03-07]

Affiliated researcher

DOI Crossref

Introducing ribosomal tandem repeat barcoding for fungi

Wurzbacher C, Larsson E, Bengtsson-Palme J, ..., Kagami M, Henrik Nilsson R

bioRxiv preprint - (-) - [2018-04-28; online 2018-04-28]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

RNA-sequencing reveals long-term effects of silver nanoparticles on human lung cells.

Gliga AR, Di Bucchianico S, Lindvall J, Fadeel B, Karlsson HL

Sci Rep 8 (1) 6668 [2018-04-27; online 2018-04-27]

Affiliated researcher

PubMed DOI Crossref

TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer.

Caja L, Dituri F, Mancarella S, ..., Giannelli G, Fabregat I

Int J Mol Sci 19 (5) - [2018-04-26; online 2018-04-26]

Affiliated researcher

PubMed DOI Crossref

Rebooting Human Immunology.

Davis MM, Brodin P

Annu. Rev. Immunol. 36 (-) 843-864 [2018-04-26; online 2018-02-28]

Affiliated researcher

PubMed DOI Crossref

Comparative omics and feeding manipulations in chicken indicate a shift of the endocrine role of visceral fat towards reproduction.

Bornelöv S, Seroussi E, Yosefi S, ..., Andersson L, Friedman-Einat M

BMC Genomics 19 (1) 295 [2018-04-26; online 2018-04-26]

Affiliated researcher

PubMed DOI Crossref

The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression.

Ali M, Ajore R, Wihlborg AK, ..., Weinhold N, Nilsson B

Nat Commun 9 (1) 1649 [2018-04-25; online 2018-04-25]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Quantification of endogenous and exogenous protein expressions of Na,K-ATPase with super-resolution PALM/STORM imaging.

Bernhem K, Blom H, Brismar H

PLoS ONE 13 (4) e0195825 [2018-04-25; online 2018-04-25]

Affiliated researcher

PubMed DOI Crossref

Experimental validation of predicted cancer genes using FRET.

Guala D, Bernhem K, Blal HA, ..., Brismar H, Sonnhammer ELL

Methods Appl Fluoresc 6 (3) 035007 [2018-04-25; online 2018-04-25]

Affiliated researcher

PubMed DOI Crossref

Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.

Fourati Z, Howard RJ, Heusser SA, ..., Lindahl E, Delarue M

Cell Reports 23 (4) 993-1004 [2018-04-24; online 2018-04-26]

Affiliated researcher

PubMed DOI Crossref

Repeated evolution of self-compatibility for reproductive assurance.

Nieuwenhuis BPS, Tusso S, Bjerling P, ..., Wolf JBW, Immler S

Nat Commun 9 (1) 1639 [2018-04-24; online 2018-04-24]

Affiliated researcher

PubMed DOI Crossref

Large-Scale Brain Simulation and Disorders of Consciousness. Mapping Technical and Conceptual Issues.

Farisco M, Kotaleski JH, Evers K

Front Psychol 9 (-) 585 [2018-04-24; online 2018-04-24]

Affiliated researcher

PubMed DOI Crossref

Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.

Tikkanen E, Gustafsson S, Amar D, ..., Ashley EA, Ingelsson E

Sci Rep 8 (1) 6451 [2018-04-24; online 2018-04-24]

Affiliated researcher

PubMed DOI Crossref

RNA Sequencing of Stentor Cell Fragments Reveals Transcriptional Changes during Cellular Regeneration.

Onsbring H, Jamy M, Ettema TJG

Curr. Biol. 28 (8) 1281-1288.e3 [2018-04-23; online 2018-04-05]

Affiliated researcher

PubMed DOI Crossref

Estimating genetic kin relationships in prehistoric populations.

Monroy Kuhn JM, Jakobsson M, Günther T

PLoS ONE 13 (4) e0195491 [2018-04-23; online 2018-04-23]

Affiliated researcher

PubMed DOI Crossref

Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenib.

Ladds MJGW, Pastor-Fernández A, Popova G, ..., Bhatia R, Laín S

PLoS ONE 13 (4) e0195956 [2018-04-23; online 2018-04-23]

Affiliated researcher

PubMed DOI Crossref

Limited reverse transcriptase activity of phi29 DNA polymerase.

Krzywkowski T, Kühnemund M, Wu D, Nilsson M

Nucleic Acids Res. 46 (7) 3625-3632 [2018-04-20; online 2018-03-20]

Affiliated researcher

PubMed DOI Crossref

In Situ Target Engagement Studies in Adherent Cells.

Axelsson H, Almqvist H, Otrocka M, ..., Lundbäck T, Seashore-Ludlow B

ACS Chem. Biol. 13 (4) 942-950 [2018-04-20; online 2018-02-21]

Affiliated researcher

PubMed DOI Crossref

A method for analysis of marker persistent organic pollutants in low-volume plasma and serum samples using 96-well plate solid phase extraction.

Stubleski J, Kukucka P, Salihovic S, ..., Lind L, Kärrman A

J Chromatogr A 1546 (-) 18-27 [2018-04-20; online 2018-02-27]

Affiliated researcher

PubMed DOI Crossref

Expression of scavenger receptor MARCO defines a targetable tumor-associated macrophage subset in non-small cell lung cancer.

La Fleur L, Boura VF, Alexeyenko A, ..., Karlsson MCI, Botling J

Int. J. Cancer - (-) - [2018-04-18; online 2018-04-18]

Affiliated researcher

PubMed DOI Crossref

Data quality of whole genome bisulfite sequencing on Illumina platforms.

Raine A, Liljedahl U, Nordlund J

PLoS ONE 13 (4) e0195972 [2018-04-18; online 2018-04-18]

Affiliated researcher

PubMed DOI Crossref

The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability.

Hafstrand I, Doorduijn EM, Sun R, ..., van Hall T, Achour A

J. Immunol. 200 (8) 2860-2868 [2018-04-15; online 2018-03-05]

Affiliated researcher

PubMed DOI Crossref

Microfluidic magnetic fluidized bed for DNA analysis in continuous flow mode.

Hernández-Neuta I, Pereiro I, Ahlford A, ..., Descroix S, Nilsson M

Biosens Bioelectron 102 (-) 531-539 [2018-04-15; online 2017-11-26]

Affiliated researcher

PubMed DOI Crossref

Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia.

Danielsson F, Fasterius E, Sullivan D, ..., Williams C, Lundberg E

Oncotarget 9 (28) 19730-19744 [2018-04-13; online 2018-04-13]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

The challenges of designing a benchmark strategy for bioinformatics pipelines in the identification of antimicrobial resistance determinants using next generation sequencing technologies.

Angers-Loustau A, Petrillo M, Bengtsson-Palme J, ..., Venturi V, Van den Eede G

F1000Res 7 (-) 459 [2018-04-13; online 2018-04-13]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Vast diversity of prokaryotic virus genomes encoding double jelly-roll major capsid proteins uncovered by genomic and metagenomic sequence analysis.

Yutin N, Bäckström D, Ettema TJG, Krupovic M, Koonin EV

Virol. J. 15 (1) 67 [2018-04-10; online 2018-04-10]

Affiliated researcher

PubMed DOI Crossref

Inter-laboratory testing of the effect of DNA blocking reagent G2 on DNA extraction from low-biomass clay samples.

Jacobsen CS, Nielsen TK, Vester JK, ..., Ekelund F, Bælum J

Sci Rep 8 (1) 5711 [2018-04-09; online 2018-04-09]

Affiliated researcher

PubMed DOI Crossref

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.

Berger AC, Korkut A, Kanchi RS, ..., Levine DA, Akbani R

Cancer Cell 33 (4) 690-705.e9 [2018-04-09; online 2018-04-02]

Affiliated researcher

PubMed DOI Crossref

Expression levels of long non-coding RNAs are prognostic for AML outcome.

Mer AS, Lindberg J, Nilsson C, ..., Lehmann S, Rantalainen M

J Hematol Oncol 11 (1) 52 [2018-04-07; online 2018-04-07]

Affiliated researcher

PubMed DOI Crossref

Conformational Intermediate That Controls KPC-2 Catalysis and Beta-Lactam Drug Resistance

Cortina GA, Hays JM, Kasson PM

ACS Catal 8 (4) 2741-2747 [2018-04-06; online 2018-02-21]

Affiliated researcher

PubMed DOI Crossref

Modular assembly of the nucleolar pre-60S ribosomal subunit.

Sanghai ZA, Miller L, Molloy KR, ..., Chait BT, Klinge S

Nature 556 (7699) 126-129 [2018-04-05; online 2018-03-05]

Jonas Barandun SciLifeLab Fellow

PubMed DOI Crossref

Copy number of pancreatic polypeptide receptor gene NPY4R correlates with body mass index and waist circumference.

Shebanits K, Andersson-Assarsson JC, Larsson I, ..., Feuk L, Larhammar D

PLoS ONE 13 (4) e0194668 [2018-04-05; online 2018-04-05]

Affiliated researcher

PubMed DOI Crossref

Systemic and specific effects of antihypertensive and lipid-lowering medication on plasma protein biomarkers for cardiovascular diseases.

Enroth S, Maturi V, Berggrund M, ..., Johansson Å, Gyllensten U

Sci Rep 8 (1) 5531 [2018-04-03; online 2018-04-03]

Affiliated researcher

PubMed DOI Crossref

LILRB1 polymorphisms influence posttransplant HCMV susceptibility and ligand interactions.

Yu K, Davidson CL, Wójtowicz A, ..., Swiss Transplant Cohort Study , Burshtyn DN

J. Clin. Invest. 128 (4) 1523-1537 [2018-04-02; online 2018-03-12]

Affiliated researcher

PubMed DOI Crossref

Distinct mechanistic responses to replication fork stalling induced by either nucleotide or protein deprivation.

Henriksson S, Groth P, Gustafsson N, Helleday T

Cell Cycle 17 (5) 568-579 [2018-04-02; online 2018-04-02]

Affiliated researcher

PubMed DOI Crossref

An Application-Directed, Versatile DNA FISH Platform for Research and Diagnostics.

Gelali E, Custodio J, Girelli G, ..., Crosetto N, Bienko M

Methods in molecular biology (Clifton, N.J.) 1766 (-) 303-333 [2018-04-02; online 2018-04-02]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

ERF deletion rescues RAS deficiency in mouse embryonic stem cells.

Mayor-Ruiz C, Olbrich T, Drosten M, ..., Ruiz S, Fernandez-Capetillo O

Genes Dev. 32 (7-8) 568-576 [2018-04-01; online 2018-04-12]

Affiliated researcher

PubMed DOI Crossref

Acquisition of a Novel Sulfur-Oxidizing Symbiont in the Gutless Marine Worm Inanidrilus exumae.

Bergin C, Wentrup C, Brewig N, ..., De Wit P, Dubilier N

Appl. Environ. Microbiol. 84 (7) - [2018-04-01; online 2018-03-19]

Affiliated researcher

DOI Crossref

Whole-Lake Sugar Addition Demonstrates Trophic Transfer of Dissolved Organic Carbon to Top Consumers

Jones RI, Kankaala P, Nykänen H, ..., Rask M, Vesala S

Ecosystems 21 (3) 495-506 [2018-04-00; online 2017-06-21]

Affiliated researcher Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

Ultraviolet Photoluminescence of Carbon Nanospheres and its Surface Plasmon-Induced Enhancement.

Gan Z, Pan P, Chen Z, ..., Chang C, Tao Y

Small 14 (16) e1704239 [2018-04-00; online 2018-03-25]

Affiliated researcher

PubMed DOI Crossref

Targeted copy number screening highlights an intragenic deletion of WDR63 as the likely cause of human occipital encephalocele and abnormal CNS development in zebrafish.

Hofmeister W, Pettersson M, Kurtoglu D, ..., Gustavsson P, Lindstrand A

Hum. Mutat. 39 (4) 495-505 [2018-04-00; online 2018-01-11]

Affiliated researcher

PubMed DOI Crossref

Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor.

Perez Boerema A, Aibara S, Paul B, ..., Lindahl E, Amunts A

Nat Plants 4 (4) 212-217 [2018-04-00; online 2018-04-02]

Affiliated researcher Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Structural basis of ligand binding modes at the neuropeptide Y Y

Yang Z, Han S, Keller M, ..., Buschauer A, Wu B

Nature 556 (7702) 520-524 [2018-04-00; online 2018-04-18]

Affiliated researcher

PubMed DOI Crossref

Structural and functional studies of Spr1654: an essential aminotransferase in teichoic acid biosynthesis in

Han X, Sun R, Sandalova T, Achour A

Open Biol 8 (4) - [2018-04-00; online 2018-04-20]

Affiliated researcher

PubMed DOI Crossref

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

Mahajan A, Wessel J, Willems SM, ..., Rotter JI, McCarthy MI

Nat. Genet. 50 (4) 559-571 [2018-04-00; online 2018-04-09]

Affiliated researcher

PubMed DOI Crossref

Platelets, NETs and cancer.

Cedervall J, Hamidi A, Olsson AK

Thromb. Res. 164 Suppl 1 (-) S148-S152 [2018-04-00; online 2018-04-29]

Affiliated researcher

PubMed DOI Crossref

Permeating disciplines: Overcoming barriers between molecular simulations and classical structure-function approaches in biological ion transport.

Howard RJ, Carnevale V, Delemotte L, Hellmich UA, Rothberg BS

Biochimica et Biophysica Acta (BBA) - Biomembranes 1860 (4) 927-942 [2018-04-00; online 2017-12-16]

Affiliated researcher Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Nutritional preferences of human gut bacteria reveal their metabolic idiosyncrasies.

Tramontano M, Andrejev S, Pruteanu M, ..., Typas A, Patil KR

Nat. Microbiol 3 (4) 514-522 [2018-04-00; online 2018-03-19]

Aleksej Zelezniak SciLifeLab Fellow

PubMed DOI Crossref

Neanderthal and Denisovan ancestry in Papuans: A functional study.

Akkuratov EE, Gelfand MS, Khrameeva EE

J Bioinform Comput Biol 16 (2) 1840011 [2018-04-00; online 2018-05-10]

Affiliated researcher

PubMed DOI Crossref

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Malik R, Chauhan G, Traylor M, ..., MEGASTROKE Consortium , MEGASTROKE Consortium:

Nat. Genet. 50 (4) 524-537 [2018-04-00; online 2018-03-12]

Affiliated researcher

PubMed DOI Crossref

Maintenance use of aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs) and prostate cancer risk.

Ma Y, Brusselaers N

Prostate Cancer Prostatic Dis. 21 (1) 147-152 [2018-04-00; online 2017-12-19]

Affiliated researcher

PubMed DOI Crossref

Maintenance proton pump inhibition therapy and risk of oesophageal cancer.

Brusselaers N, Engstrand L, Lagergren J

Cancer Epidemiol 53 (-) 172-177 [2018-04-00; online 2018-02-22]

Affiliated researcher

DOI Crossref

Learning Surrogate Models of Document Image Quality Metrics for Automated Document Image Processing

Singh P, Vats E, Hast A

- - (-) - [2018-04-00; online 2018-04-00]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors.

Oei VYS, Siernicka M, Graczyk-Jarzynka A, ..., Kyte JA, Malmberg KJ

Cancer Immunol Res 6 (4) 467-480 [2018-04-00; online 2018-02-19]

Affiliated researcher

PubMed DOI Crossref

Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT.

Abadpour S, Halvorsen B, Sahraoui A, ..., Aukrust P, Scholz H

J. Mol. Endocrinol. 60 (3) 171-183 [2018-04-00; online 2018-01-12]

Affiliated researcher

PubMed DOI Crossref

High plasma organochlorine pesticide levels are related to increased biological age as calculated by DNA methylation analysis.

Lind PM, Salihovic S, Lind L

Environ Int 113 (-) 109-113 [2018-04-00; online 2018-02-06]

Affiliated researcher

PubMed DOI Crossref

Gating interaction maps reveal a noncanonical electromechanical coupling mode in the Shaker K+ channel.

Fernández-Mariño AI, Harpole TJ, Oelstrom K, Delemotte L, Chanda B

Nat. Struct. Mol. Biol. 25 (4) 320-326 [2018-04-00; online 2018-03-26]

Affiliated researcher Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4

Bhandage AK, Jin Z, Korol SV, ..., Kamali-Moghaddam M, Birnir B

EBioMedicine 30 (-) 283-294 [2018-04-00; online 2018-03-28]

Affiliated researcher

PubMed DOI Crossref

Effect of Ca2+ on the promiscuous target-protein binding of calmodulin.

Westerlund AM, Delemotte L

PLoS Comput Biol 14 (4) e1006072 [2018-04-00; online 2018-04-03]

Affiliated researcher Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

EOMES-positive CD4

Chemin K, Ramsköld D, Diaz-Gallo LM, ..., Catrina A, Malmström V

Eur. J. Immunol. 48 (4) 655-669 [2018-04-00; online 2018-02-28]

Affiliated researcher

PubMed DOI Crossref

Digital image analysis in breast pathology-from image processing techniques to artificial intelligence.

Robertson S, Azizpour H, Smith K, Hartman J

Transl Res 194 (-) 19-35 [2018-04-00; online 2017-11-07]

Affiliated researcher

PubMed DOI Crossref

Differential removal of human pathogenic viruses from sewage by conventional and ozone treatments.

Wang H, Sikora P, Rutgersson C, ..., Larsson DGJ, Norder H

Int J Hyg Environ Health 221 (3) 479-488 [2018-04-00; online 2018-02-01]

Affiliated researcher

PubMed DOI Crossref

Conformational landscapes of membrane proteins delineated by enhanced sampling molecular dynamics simulations.

Harpole TJ, Delemotte L

Biochimica et Biophysica Acta (BBA) - Biomembranes 1860 (4) 909-926 [2018-04-00; online 2017-11-04]

Affiliated researcher Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Confocal super-resolution imaging of the glomerular filtration barrier enabled by tissue expansion.

Unnersjö-Jess D, Scott L, Sevilla SZ, ..., Blom H, Brismar H

Kidney Int. 93 (4) 1008-1013 [2018-04-00; online 2017-12-11]

Affiliated researcher

PubMed DOI Crossref

Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma.

Huvila J, Laajala TD, Edqvist PH, ..., Aittokallio T, Auranen A

Gynecol. Oncol. 149 (1) 173-180 [2018-04-00; online 2018-03-02]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Clinical relevance of integrin alpha 4 in gastrointestinal stromal tumours.

Pulkka OP, Mpindi JP, Tynninen O, ..., Sihto H, Joensuu H

J. Cell. Mol. Med. 22 (4) 2220-2230 [2018-04-00; online 2018-01-29]

Affiliated researcher

PubMed DOI Crossref

Biological/Genetic Regulation of Physical Activity Level: Consensus from GenBioPAC.

Lightfoot JT, DE Geus EJC, Booth FW, ..., Garland T, Bouchard C

Med Sci Sports Exerc 50 (4) 863-873 [2018-04-00; online 2017-11-23]

Affiliated researcher

PubMed DOI Crossref

Assembly and structure of the SSU processome-a nucleolar precursor of the small ribosomal subunit.

Barandun J, Hunziker M, Klinge S

Curr. Opin. Struct. Biol. 49 (-) 85-93 [2018-04-00; online 2018-02-04]

Jonas Barandun SciLifeLab Fellow

DOI Crossref

An integrated all foil based micro device for point of care diagnostic applications

Bose I, Ohlander A, Kutter C, Russom A

Sensors and Actuators B: Chemical 259 (-) 917-925 [2018-04-00; online 2018-04-00]

Affiliated researcher

PubMed DOI Crossref

An in vitro evaluation of browser and grazer fermentation efficiency and microbiota using European moose spring and summer foods.

Krizsan SJ, Mateos-Rivera A, Bertilsson S, ..., Gidlund H, Huhtanen P

Ecol Evol 8 (8) 4183-4196 [2018-04-00; online 2018-03-31]

Affiliated researcher

PubMed DOI Crossref

Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes.

Klaesson A, Grannas K, Ebai T, ..., Söderberg O, Landegren U

Sci Rep 8 (1) 5400 [2018-03-29; online 2018-03-29]

Affiliated researcher

PubMed DOI Crossref

Targeted Long-Read Sequencing of a Locus Under Long-Term Balancing Selection in Capsella.

Bachmann JA, Tedder A, Laenen B, Steige KA, Slotte T

G3 8 (4) 1327-1333 [2018-03-28; online 2018-03-28]

Affiliated researcher SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Strong impact on plasma protein profiles by precentrifugation delay but not by repeated freeze-thaw cycles, as analyzed using multiplex proximity extension assays.

Shen Q, Björkesten J, Galli J, ..., Tybring G, Landegren U

Clin. Chem. Lab. Med. 56 (4) 582-594 [2018-03-28; online 2017-10-19]

Affiliated researcher

PubMed DOI Crossref

PON-tstab: Protein Variant Stability Predictor. Importance of Training Data Quality.

Yang Y, Urolagin S, Niroula A, ..., Shen B, Vihinen M

Int J Mol Sci 19 (4) - [2018-03-28; online 2018-03-28]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Computer simulations of the catalytic mechanism of wild-type and mutant β-phosphoglucomutase.

Barrozo A, Liao Q, Esguerra M, ..., Williams NH, Kamerlin SCL

Org. Biomol. Chem. 16 (12) 2060-2073 [2018-03-28; online 2018-03-06]

Affiliated researcher

PubMed DOI Crossref

AMYCNE: Confident copy number assessment using whole genome sequencing data.

Eisfeldt J, Nilsson D, Andersson-Assarsson JC, Lindstrand A

PLoS ONE 13 (3) e0189710 [2018-03-26; online 2018-03-26]

Affiliated researcher

PubMed DOI Crossref

A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons.

Södersten E, Toskas K, Rraklli V, ..., Perlmann T, Holmberg J

Nat Commun 9 (1) 1226 [2018-03-26; online 2018-03-26]

Affiliated researcher

PubMed DOI Crossref

Protein Expression in Tonsillar and Base of Tongue Cancer and in Relation to Human Papillomavirus (HPV) and Clinical Outcome.

Ramqvist T, Näsman A, Franzén B, ..., Dalianis T, Munck-Wikland E

Int J Mol Sci 19 (4) - [2018-03-25; online 2018-03-25]

Affiliated researcher

PubMed DOI Crossref

Suppression of diabetes by accumulation of non-islet-specific CD8 + effector T cells in pancreatic islets.

Christoffersson G, Chodaczek G, Ratliff SS, Coppieters K, von Herrath MG

Sci Immunol 3 (21) - [2018-03-23; online 2018-03-25]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood.

Jiang J, Thalamuthu A, Ho JE, ..., Sachdev PS, Mather KA

Front Genet 9 (-) 97 [2018-03-23; online 2018-03-23]

Affiliated researcher

PubMed DOI Crossref

Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury.

Dias DO, Kim H, Holl D, ..., Göritz C, Frisén J

Cell 173 (1) 153-165.e22 [2018-03-22; online 2018-03-01]

Affiliated researcher

PubMed DOI Crossref

Peptide ion channel toxins from the bootlace worm, the longest animal on Earth.

Jacobsson E, Andersson HS, Strand M, ..., Tytgat J, Göransson U

Sci Rep 8 (1) 4596 [2018-03-22; online 2018-03-22]

Affiliated researcher

PubMed DOI Crossref

Maltreatment, the Oxytocin Receptor Gene, and Conduct Problems Among Male and Female Teenagers.

Andreou D, Comasco E, Åslund C, Nilsson KW, Hodgins S

Front. Hum. Neurosci. 12 (-) 112 [2018-03-22; online 2018-03-22]

Affiliated researcher Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Introduction of Intrinsic Kinetics of Protein-Ligand Interactions and Their Implications for Drug Design.

Linkuvienė V, Talibov VO, Danielson UH, Matulis D

J. Med. Chem. 61 (6) 2292-2302 [2018-03-22; online 2018-03-02]

Affiliated researcher

PubMed DOI Crossref

Authorship attribution based on Life-Like Network Automata.

Machicao J, Corrêa EA, Miranda GHB, Amancio DR, Bruno OM

PLoS ONE 13 (3) e0193703 [2018-03-22; online 2018-03-22]

Gisele Miranda SciLifeLab Fellow

PubMed DOI Crossref

Spironaphthoxazine switchable dyes for biological imaging.

Xiong Y, Vargas Jentzsch A, Osterrieth JWM, ..., Eggeling C, Anderson HL

Chem Sci 9 (11) 3029-3040 [2018-03-21; online 2018-02-20]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Role of Ligand-Driven Conformational Changes in Enzyme Catalysis: Modeling the Reactivity of the Catalytic Cage of Triosephosphate Isomerase.

Kulkarni YS, Liao Q, Byléhn F, ..., Richard JP, Kamerlin SCL

J. Am. Chem. Soc. 140 (11) 3854-3857 [2018-03-21; online 2018-03-13]

Affiliated researcher

PubMed DOI Crossref

Randomised study shows that repeated self-sampling and HPV test has more than two-fold higher detection rate of women with CIN2+ histology than Pap smear cytology.

Gustavsson I, Aarnio R, Berggrund M, ..., Olovsson M, Gyllensten U

Br. J. Cancer 118 (6) 896-904 [2018-03-20; online 2018-02-13]

Affiliated researcher

PubMed DOI Crossref

A Space Efficient Direct Access Data Compression Approach for Mass Spectrometry Imaging.

Källback P, Nilsson A, Shariatgorji M, Andrén PE

Anal. Chem. 90 (6) 3676-3682 [2018-03-20; online 2018-03-08]

Affiliated researcher

PubMed DOI Crossref

ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease.

Bremer HD, Landegren N, Sjöberg R, ..., Kämpe O, Hansson-Hamlin H

Sci Rep 8 (1) 4852 [2018-03-19; online 2018-03-19]

Affiliated researcher

PubMed DOI Crossref

Single molecule real-time (SMRT) sequencing comes of age: applications and utilities for medical diagnostics.

Ardui S, Ameur A, Vermeesch JR, Hestand MS

Nucleic Acids Res. 46 (5) 2159-2168 [2018-03-16; online 2018-02-06]

Affiliated researcher

PubMed DOI Crossref

Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.

Galanos P, Pappas G, Polyzos A, ..., Bartek J, Gorgoulis VG

Genome Biol. 19 (1) 37 [2018-03-16; online 2018-03-16]

Affiliated researcher

PubMed DOI Crossref

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S

Nat Commun 9 (1) 1107 [2018-03-16; online 2018-03-16]

Affiliated researcher SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Protein profiling in serum after traumatic brain injury in rats reveals potential injury markers.

Thelin EP, Just D, Frostell A, ..., Nilsson P, Bellander BM

Behav. Brain Res. 340 (-) 71-80 [2018-03-15; online 2016-08-31]

Affiliated researcher

PubMed DOI Crossref

Lipids Shape the Electron Acceptor-Binding Site of the Peripheral Membrane Protein Dihydroorotate Dehydrogenase.

Costeira-Paulo J, Gault J, Popova G, ..., Marklund EG, Landreh M

Cell Chem Biol 25 (3) 309-317.e4 [2018-03-15; online 2018-01-18]

Affiliated researcher

DOI Crossref

Distribution and drivers of symbiotic and free-living diazotrophic cyanobacteria in the western tropical South Pacific

Stenegren M, Caputo A, Berg C, Bonnet S, Foster RA

Biogeosciences 15 (5) 1559-1578 [2018-03-15; online 2018-03-15]

Affiliated researcher

PubMed DOI Crossref

Wing bone geometry reveals active flight in Archaeopteryx.

Voeten DFAE, Cubo J, de Margerie E, ..., Tafforeau P, Sanchez S

Nat Commun 9 (1) 923 [2018-03-13; online 2018-03-13]

Affiliated researcher

PubMed DOI Crossref

Structural Transitions in Ceramide Cubic Phases during Formation of the Human Skin Barrier.

Wennberg CL, Narangifard A, Lundborg M, Norlén L, Lindahl E

Biophys. J. 114 (5) 1116-1127 [2018-03-13; online 2018-03-15]

Affiliated researcher

PubMed DOI Crossref

A comprehensive genomic history of extinct and living elephants.

Palkopoulou E, Lipson M, Mallick S, ..., Poinar H, Reich D

Proc. Natl. Acad. Sci. U.S.A. 115 (11) E2566-E2574 [2018-03-13; online 2018-02-26]

Affiliated researcher

PubMed DOI Crossref

High-resolution detection of chromosomal rearrangements in leukemias through mate pair whole genome sequencing.

Tran AN, Taylan F, Zachariadis V, ..., Nilsson D, Barbany G

PLoS ONE 13 (3) e0193928 [2018-03-12; online 2018-03-12]

Affiliated researcher

PubMed DOI Crossref

Membrane protein serendipity.

von Heijne G

J. Biol. Chem. 293 (10) 3470-3476 [2018-03-09; online 2018-03-11]

Affiliated researcher

PubMed DOI Crossref

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis.

Dias JT, Svedberg G, Nystrand M, Andersson-Svahn H, Gantelius J

J Vis Exp - (133) - [2018-03-07; online 2018-03-07]

Affiliated researcher

PubMed DOI Crossref

Sexual dimorphism in the width of the mouse synaptonemal complex.

Agostinho A, Kouznetsova A, Hernández-Hernández A, ..., Brismar H, Höög C

J. Cell. Sci. 131 (5) - [2018-03-06; online 2018-03-06]

Affiliated researcher

PubMed DOI Crossref

Characterization of the human RFX transcription factor family by regulatory and target gene analysis.

Sugiaman-Trapman D, Vitezic M, Jouhilahti EM, ..., Kere J, Swoboda P

BMC Genomics 19 (1) 181 [2018-03-06; online 2018-03-06]

Affiliated researcher

PubMed DOI Crossref

CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium.

Mönnich M, Borgeskov L, Breslin L, ..., Larsen LA, Pedersen LB

Cell Reports 22 (10) 2584-2592 [2018-03-06; online 2018-03-08]

Affiliated researcher

PubMed DOI Crossref

Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.

Azimi A, Caramuta S, Seashore-Ludlow B, ..., Uhlen M, Maddalo G

Mol Syst Biol 14 (3) e7858 [2018-03-05; online 2018-03-05]

Affiliated researcher

PubMed DOI Crossref

DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia.

Borssén M, Nordlund J, Haider Z, ..., Lönnerholm G, Degerman S

Clin Epigenetics 10 (-) 31 [2018-03-05; online 2018-03-05]

Affiliated researcher

PubMed DOI Crossref

Synthesis of Galactosylated Glycosylphosphatidylinositol Derivatives from Trypanosoma brucei.

Grube M, Lee BY, Garg M, ..., Seeberger PH, Varón Silva D

Chemistry 24 (13) 3271-3282 [2018-03-02; online 2018-02-01]

Affiliated researcher

PubMed DOI Crossref

Influenza Hemifusion Phenotype Depends on Membrane Context: Differences in Cell-Cell and Virus-Cell Fusion.

Zawada KE, Okamoto K, Kasson PM

J. Mol. Biol. 430 (5) 594-601 [2018-03-02; online 2018-02-02]

Affiliated researcher

PubMed DOI Crossref

Discovery of coding regions in the human genome by integrated proteogenomics analysis workflow.

Zhu Y, Orre LM, Johansson HJ, ..., Branca RMM, Lehtiö J

Nat Commun 9 (1) 903 [2018-03-02; online 2018-03-02]

Affiliated researcher

PubMed DOI Crossref

TGF-β Family Signaling in Ductal Differentiation and Branching Morphogenesis.

Kahata K, Maturi V, Moustakas A

Cold Spring Harbor Perspectives in Biology 10 (3) - [2018-03-01; online 2018-03-01]

Affiliated researcher

PubMed DOI Crossref

STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells.

Liu Y, Lv J, Liu J, ..., Qin FX, Huang B

J. Clin. Invest. 128 (3) 1057-1073 [2018-03-01; online 2018-02-12]

Affiliated researcher

PubMed DOI Crossref

Perspective: APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution.

Venkatesan S, Rosenthal R, Kanu N, ..., Harris RS, Swanton C

Ann. Oncol. 29 (3) 563-572 [2018-03-01; online 2018-01-13]

Affiliated researcher

PubMed DOI Crossref

Impact of genetic risk loci for multiple sclerosis on expression of proximal genes in patients.

James T, Lindén M, Morikawa H, ..., Gomez-Cabrero D, Kockum I

Hum. Mol. Genet. 27 (5) 912-928 [2018-03-01; online 2018-01-13]

Affiliated researcher

PubMed DOI Crossref

Genetic variants influencing phenotypic variance heterogeneity.

Ek WE, Rask-Andersen M, Karlsson T, ..., Gyllensten U, Johansson Å

Hum. Mol. Genet. 27 (5) 799-810 [2018-03-01; online 2018-01-13]

Affiliated researcher

PubMed DOI Crossref

The neutrophil: one cell on many missions or many cells with different agendas?

Christoffersson G, Phillipson M

Cell Tissue Res. 371 (3) 415-423 [2018-03-00; online 2018-02-12]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration.

Pettersson-Klein AT, Izadi M, Ferreira DMS, ..., Griffin PR, Ruas JL

Mol Metab 9 (-) 28-42 [2018-03-00; online 2018-02-03]

Affiliated researcher

PubMed DOI Crossref

Slime mould: The fundamental mechanisms of biological cognition.

Vallverdú J, Castro O, Mayne R, ..., Zenil H, Adamatzky A

BioSystems 165 (-) 57-70 [2018-03-00; online 2018-01-08]

Affiliated researcher

PubMed DOI Crossref

Recon3D enables a three-dimensional view of gene variation in human metabolism.

Brunk E, Sahoo S, Zielinski DC, ..., Thiele I, Palsson BO

Nat. Biotechnol. 36 (3) 272-281 [2018-03-00; online 2018-02-19]

Avlant Nilsson DDLS Fellow

PubMed DOI Crossref

Nubbin isoform antagonism governs Drosophila intestinal immune homeostasis.

Lindberg BG, Tang X, Dantoft W, ..., Lindvall JM, Engström Y

PLoS Pathog 14 (3) e1006936 [2018-03-00; online 2018-03-02]

Affiliated researcher

PubMed DOI Crossref

Methods for estimation of model accuracy in CASP12.

Elofsson A, Joo K, Keasar C, ..., Uziela K, Wallner B

Proteins 86 Suppl 1 (-) 361-373 [2018-03-00; online 2017-10-17]

Affiliated researcher

PubMed DOI Crossref

In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and

El-Heliebi A, Hille C, Laxman N, ..., Nilsson M, Sedlmayr P

Clin. Chem. 64 (3) 536-546 [2018-03-00; online 2018-01-04]

Affiliated researcher

PubMed DOI Crossref

Hypericin affects cancer side populations via competitive inhibition of BCRP.

Vargová J, Mikeš J, Jendželovský R, ..., Kozubík A, Fedoročko P

Biomed. Pharmacother. 99 (-) 511-522 [2018-03-00; online 2018-02-20]

Affiliated researcher

DOI Crossref

High methylmercury formation in ponds fueled by fresh humic and algal derived organic matter

Herrero Ortega S, Catalán N, Björn E, ..., Levanoni O, Bravo AG

Limnol. Oceanogr. 63 (S1) S44-S53 [2018-03-00; online 2017-11-10]

Affiliated researcher

PubMed DOI Crossref

Geobacteraceae are important members of mercury-methylating microbial communities of sediments impacted by waste water releases.

Bravo AG, Zopfi J, Buck M, ..., Poté J, Cosio C

ISME J 12 (3) 802-812 [2018-03-00; online 2018-01-10]

Affiliated researcher

PubMed DOI Crossref

Fluorescent Diarylethene Photoswitches-A Universal Tool for Super-Resolution Microscopy in Nanostructured Materials.

Nevskyi O, Sysoiev D, Dreier J, ..., Huhn T, Wöll D

Small 14 (10) 1703333 [2018-03-00; online 2018-01-11]

Affiliated researcher Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

First de novo whole genome sequencing and assembly of the pink-footed goose.

Pujolar JM, Dalén L, Olsen RA, Hansen MM, Madsen J

Genomics 110 (2) 75-79 [2018-03-00; online 2017-08-30]

Affiliated researcher

DOI Crossref

Femtosecond X-ray Fourier holography imaging of free-flying nanoparticles

Gorkhover T, Ulmer A, Ferguson K, ..., Hajdu J, Bostedt C

Nature Photon 12 (3) 150-153 [2018-03-00; online 2018-02-26]

Affiliated researcher

PubMed DOI Crossref

Diffuse intrinsic pontine gliomas (DIPG) at recurrence: is there a window to test new therapies in some patients?

Lobon-Iglesias MJ, Giraud G, Castel D, ..., Varlet P, Grill J

J. Neurooncol. 137 (1) 111-118 [2018-03-00; online 2017-12-02]

Affiliated researcher

PubMed DOI Crossref

Contrasting patterns of genome-level diversity across distinct co-occurring bacterial populations.

Garcia SL, Stevens SLR, Crary B, ..., Malmstrom RR, McMahon KD

ISME J 12 (3) 742-755 [2018-03-00; online 2017-12-08]

Affiliated researcher Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

Associations Between MAOA-uVNTR Genotype, Maltreatment, MAOA Methylation, and Alcohol Consumption in Young Adult Males.

Bendre M, Comasco E, Checknita D, ..., Hodgins S, Nilsson KW

Alcohol Clin Exp Res 42 (3) 508-519 [2018-03-00; online 2018-01-31]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans

Mardinoglu A, Wu H, Bjornson E, ..., Taskinen MR, Borén J

Cell Metabolism 27 (3) 559-571.e5 [2018-03-00; online 2018-03-00]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

A genomic map of clinal variation across the European rabbit hybrid zone.

Rafati N, Blanco-Aguiar JA, Rubin CJ, ..., Andersson L, Carneiro M

Mol. Ecol. 27 (6) 1457-1478 [2018-03-00; online 2018-02-11]

Affiliated researcher

PubMed DOI Crossref

Integrative Personal Omics Profiles during Periods of Weight Gain and Loss.

Piening BD, Zhou W, Contrepois K, ..., Weinstock GM, Snyder MP

Cell Systems 6 (2) 157-170.e8 [2018-02-28; online 2018-01-17]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

GeneGini: Assessment via the Gini Coefficient of Reference "Housekeeping" Genes and Diverse Human Transporter Expression Profiles.

O'Hagan S, Wright Muelas M, Day PJ, Lundberg E, Kell DB

Cell Systems 6 (2) 230-244.e1 [2018-02-28; online 2018-02-07]

Affiliated researcher

PubMed DOI Crossref

Current applications of antibody microarrays.

Chen Z, Dodig-Crnković T, Schwenk JM, Tao SC

Clin Proteomics 15 (-) 7 [2018-02-28; online 2018-02-28]

Affiliated researcher

PubMed DOI Crossref

Cholesterol enhances influenza binding avidity by controlling nanoscale receptor clustering.

Goronzy IN, Rawle RJ, Boxer SG, Kasson PM

Chem Sci 9 (8) 2340-2347 [2018-02-28; online 2018-01-24]

Affiliated researcher

PubMed DOI Crossref

The ZBED6-IGF2 axis has a major effect on growth of skeletal muscle and internal organs in placental mammals.

Younis S, Schönke M, Massart J, ..., Zierath JR, Andersson L

Proc. Natl. Acad. Sci. U.S.A. 115 (9) E2048-E2057 [2018-02-27; online 2018-02-12]

Affiliated researcher

PubMed DOI Crossref

Identification of Discriminating Metabolic Pathways and Metabolites in Human PBMCs Stimulated by Various Pathogenic Agents.

Zhang X, Mardinoglu A, Joosten LAB, ..., Netea MG, Groen AK

Front. Physiol. 9 (-) 139 [2018-02-27; online 2018-02-27]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Prediction of Ordered Water Molecules in Protein Binding Sites from Molecular Dynamics Simulations: The Impact of Ligand Binding on Hydration Networks.

Rudling A, Orro A, Carlsson J

J Chem Inf Model 58 (2) 350-361 [2018-02-26; online 2018-02-05]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Somatic mutagenesis in satellite cells associates with human skeletal muscle aging.

Franco I, Johansson A, Olsson K, ..., Fischer H, Eriksson M

Nat Commun 9 (1) 800 [2018-02-23; online 2018-02-23]

Affiliated researcher

PubMed DOI Crossref

Symbiosis in the microbial world: from ecology to genome evolution.

Raina JB, Eme L, Pollock FJ, ..., Archibald JM, Williams TA

Biol Open 7 (2) - [2018-02-22; online 2018-02-22]

Affiliated researcher

DOI Crossref

Interferometric scattering (iSCAT) microscopy: studies of biological membrane dynamics

Reina F, Galiani S, Shrestha D, ..., Eggeling C, Cole D

- - (-) - [2018-02-20; online 2018-02-20]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Antibodies in children with malaria to PfEMP1, RIFIN and SURFIN expressed at the Plasmodium falciparum parasitized red blood cell surface.

Quintana MDP, Ch'ng JH, Moll K, ..., Qundos U, Wahlgren M

Sci Rep 8 (1) 3262 [2018-02-19; online 2018-02-19]

Affiliated researcher

PubMed DOI Crossref

JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion.

Sundqvist A, Morikawa M, Ren J, ..., van Dam H, Ten Dijke P

Nucleic Acids Res. 46 (3) 1180-1195 [2018-02-16; online 2017-12-01]

Affiliated researcher

PubMed DOI Crossref

HiCapTools: a software suite for probe design and proximity detection for targeted chromosome conformation capture applications.

Anil A, Spalinskas R, Åkerborg Ö, Sahlén P, Berger B

Bioinformatics 34 (4) 675-677 [2018-02-15; online 2018-02-15]

Affiliated researcher

PubMed DOI Crossref

Permeability and ammonia selectivity in aquaporin TIP2;1: linking structure to function.

Lindahl V, Gourdon P, Andersson M, Hess B

Sci Rep 8 (1) 2995 [2018-02-14; online 2018-02-14]

Affiliated researcher

PubMed DOI Crossref

How many human proteoforms are there?

Aebersold R, Agar JN, Amster IJ, ..., Young NL, Zhang B

Nat. Chem. Biol. 14 (3) 206-214 [2018-02-14; online 2018-02-15]

Affiliated researcher

PubMed DOI Crossref

Affinity proteomic profiling of plasma for proteins associated to area-based mammographic breast density.

Byström S, Eklund M, Hong MG, ..., Schwenk JM, Gabrielson M

Breast Cancer Res. 20 (1) 14 [2018-02-14; online 2018-02-14]

Affiliated researcher

PubMed DOI Crossref

Advancing the immunoaffinity platform AFFIRM to targeted measurements of proteins in serum in the pg/ml range.

Säll A, Corbee D, Vikström S, ..., Persson H, Waldemarson S

PLoS ONE 13 (2) e0189116 [2018-02-13; online 2018-02-13]

Affiliated researcher

DOI Crossref

Efficient DNA-assisted synthesis of trans-membrane gold nanowires

Guo M, Hernández-Neuta I, Madaboosi N, Nilsson M, van der Wijngaart W

Microsyst. Nanoeng. 4 (1) 17084 [2018-02-12; online 2018-02-12]

Affiliated researcher

PubMed DOI Crossref

High prevalence of gait abnormalities in pugs.

Rohdin C, Jäderlund KH, Ljungvall I, Lindblad-Toh K, Häggström J

Vet. Rec. 182 (6) 167 [2018-02-10; online 2018-02-05]

Affiliated researcher

PubMed DOI Crossref

A flow-through nanoporous alumina trypsin bioreactor for mass spectrometry peptide fingerprinting.

Kjellander M, Billinger E, Ramachandraiah H, ..., Bergström Lind S, Johansson G

J Proteomics 172 (-) 165-172 [2018-02-10; online 2017-09-21]

Affiliated researcher

PubMed DOI Crossref

Evolution of neuropeptide signalling systems.

Elphick MR, Mirabeau O, Larhammar D

J. Exp. Biol. 221 (Pt 3) - [2018-02-09; online 2018-02-09]

Affiliated researcher

PubMed DOI Crossref

Particle Manipulation Methods in Droplet Microfluidics.

Tenje M, Fornell A, Ohlin M, Nilsson J

Anal. Chem. 90 (3) 1434-1443 [2018-02-06; online 2017-12-21]

Affiliated researcher

PubMed DOI Crossref

MonoRes: Automatic and Accurate Estimation of Local Resolution for Electron Microscopy Maps.

Vilas JL, Gómez-Blanco J, Conesa P, ..., Vargas J, Sorzano COS

Structure 26 (2) 337-344.e4 [2018-02-06; online 2018-01-27]

Affiliated researcher

PubMed DOI Crossref

MYCN-amplified neuroblastoma maintains an aggressive and undifferentiated phenotype by deregulation of estrogen and NGF signaling.

Dzieran J, Rodriguez Garcia A, Westermark UK, ..., Lehtiö J, Arsenian-Henriksson M

Proc. Natl. Acad. Sci. U.S.A. 115 (6) E1229-E1238 [2018-02-06; online 2018-01-26]

Affiliated researcher

PubMed DOI Crossref

Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation.

Agudelo LZ, Ferreira DMS, Cervenka I, ..., Berggren PO, Ruas JL

Cell Metab. 27 (2) 378-392.e5 [2018-02-06; online 2018-02-08]

Affiliated researcher

PubMed DOI Crossref

Human NUDT22 Is a UDP-Glucose/Galactose Hydrolase Exhibiting a Unique Structural Fold.

Carter M, Jemth AS, Carreras-Puigvert J, ..., Helleday T, Stenmark P

Structure 26 (2) 295-303.e6 [2018-02-06; online 2018-02-08]

Affiliated researcher

PubMed DOI Crossref

Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity.

Narwal M, Jemth AS, Gustafsson R, ..., Helleday T, Stenmark P

Biochemistry 57 (5) 593-603 [2018-02-06; online 2018-01-16]

Affiliated researcher

PubMed DOI Crossref

Basal Ganglia Neuromodulation Over Multiple Temporal and Structural Scales-Simulations of Direct Pathway MSNs Investigate the Fast Onset of Dopaminergic Effects and Predict the Role of Kv4.2.

Lindroos R, Dorst MC, Du K, ..., Silberberg G, Hellgren Kotaleski J

Front Neural Circuits 12 (-) 3 [2018-02-06; online 2018-02-06]

Affiliated researcher

PubMed DOI Crossref

Phenotypic co-receptor tropism and Maraviroc sensitivity in HIV-1 subtype C from East Africa.

Siddik AB, Haas A, Rahman MS, ..., Klimkait T, Neogi U

Sci Rep 8 (1) 2363 [2018-02-05; online 2018-02-05]

Affiliated researcher

PubMed DOI Crossref

ITGB1-dependent upregulation of Caveolin-1 switches TGFβ signalling from tumour-suppressive to oncogenic in prostate cancer.

Pellinen T, Blom S, Sánchez S, ..., Kallioniemi O, Del Pozo MA

Sci Rep 8 (1) 2338 [2018-02-05; online 2018-02-05]

Affiliated researcher

DOI Crossref

Binary particle separation in droplet microfluidics using acoustophoresis

Fornell A, Cushing K, Nilsson J, Tenje M

Appl. Phys. Lett. 112 (6) 063701 [2018-02-05; online 2018-02-06]

Affiliated researcher

PubMed DOI Crossref

Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin.

Teixeira PF, Masuyer G, Pinho CM, ..., Stenmark P, Glaser E

J. Mol. Biol. 430 (3) 348-362 [2018-02-02; online 2017-11-26]

Affiliated researcher

PubMed DOI Crossref

Synaptic markers of cognitive decline in neurodegenerative diseases: a proteomic approach.

Bereczki E, Branca RM, Francis PT, ..., Lehtiö J, Aarsland D

Brain 141 (2) 582-595 [2018-02-01; online 2018-01-13]

Affiliated researcher

PubMed DOI Crossref

Origin and Evolution of the Bartonella Gene Transfer Agent.

Tamarit D, Neuvonen MM, Engel P, Guy L, Andersson SGE

Mol. Biol. Evol. 35 (2) 451-464 [2018-02-01; online 2017-11-22]

Affiliated researcher

PubMed DOI Crossref

Formation of mercury methylation hotspots as a consequence of forestry operations.

Eklöf K, Bishop K, Bertilsson S, ..., Kronberg RM, Bravo AG

Sci. Total Environ. 613-614 (-) 1069-1078 [2018-02-01; online 2017-09-22]

Affiliated researcher

PubMed DOI Crossref

Evolution of the receptors for growth hormone, prolactin, erythropoietin and thrombopoietin in relation to the vertebrate tetraploidizations.

Ocampo Daza D, Larhammar D

Gen. Comp. Endocrinol. 257 (-) 143-160 [2018-02-01; online 2017-06-23]

Affiliated researcher

PubMed DOI Crossref

U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius B, Melin B, Enblad G, ..., Palmqvist R, Sjöblom T

Acta Oncol 57 (2) 187-194 [2018-02-00; online 2017-06-20]

Affiliated researcher

PubMed DOI Crossref

Targeted proteomic analysis of habitual coffee consumption.

Cornelis MC, Gustafsson S, Ärnlöv J, ..., Lind L, Ingelsson E

J. Intern. Med. 283 (2) 200-211 [2018-02-00; online 2017-11-16]

Affiliated researcher

PubMed DOI Crossref

Quantitative image analysis of protein expression and colocalisation in skin sections.

Zhang H, Ericsson M, Virtanen M, ..., Vahlquist A, Törmä H

Exp. Dermatol. 27 (2) 196-199 [2018-02-00; online 2018-01-09]

Affiliated researcher

PubMed DOI Crossref

Protection goals must guide risk assessment for antibiotics.

Bengtsson-Palme J, Larsson DGJ

Environ Int 111 (-) 352-353 [2018-02-00; online 2017-10-31]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Probing the activity of a recombinant Zn

Ravishankar H, Barth A, Andersson M

Biopolymers 109 (2) - [2018-02-00; online 2017-11-23]

Affiliated researcher

PubMed DOI Crossref

Plasma soluble factor following two decades prolonged suppressive antiretroviral therapy in HIV-1-positive males: A cross-sectional study.

Sperk M, Zhang W, Nowak P, Neogi U

Medicine (Baltimore) 97 (5) e9759 [2018-02-00; online 2018-02-01]

Affiliated researcher

PubMed DOI Crossref

PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells.

Pierozan P, Karlsson O

Arch. Toxicol. 92 (2) 705-716 [2018-02-00; online 2017-10-23]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

Iodine-lithium-alpha-dextrin (ILαD) against Staphylococcus aureus skin infections: a comparative study of in-vitro bactericidal activity and cytotoxicity between ILαD and povidone-iodine.

Zisi AP, Exindari MK, Siska EK, Koliakos GG

J. Hosp. Infect. 98 (2) 134-140 [2018-02-00; online 2017-07-20]

Affiliated researcher

PubMed DOI Crossref

In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation.

Zieba A, Ponten F, Uhlén M, Landegren U

Mod. Pathol. 31 (2) 253-263 [2018-02-00; online 2017-09-22]

Affiliated researcher

PubMed DOI Crossref

In Vivo Visualization of β-Cells by Targeting of GPR44.

Eriksson O, Johnström P, Cselenyi Z, ..., Skrtic S, Korsgren O

Diabetes 67 (2) 182-192 [2018-02-00; online 2017-12-05]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Evaluation of Post-Mortem Effects on Global Brain DNA Methylation and Hydroxymethylation.

Sjöholm LK, Ransome Y, Ekström TJ, Karlsson O

Basic Clin. Pharmacol. Toxicol. 122 (2) 208-213 [2018-02-00; online 2017-11-13]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

Enzymatic degradation of hyaluronan hydrogels with different capacity for in situ bio-mineralization.

Shi L, Zhang Y, Ossipov D

Biopolymers 109 (2) - [2018-02-00; online 2017-11-27]

Affiliated researcher

PubMed DOI Crossref

Conserved properties of dentate gyrus neurogenesis across postnatal development revealed by single-cell RNA sequencing.

Hochgerner H, Zeisel A, Lönnerberg P, Linnarsson S

Nat. Neurosci. 21 (2) 290-299 [2018-02-00; online 2018-01-15]

Affiliated researcher

PubMed DOI Crossref

Comparative Action of Cardiotonic Steroids on Intracellular Processes in Rat Cortical Neurons.

Lopachev AV, Lopacheva OM, Nikiforova KA, ..., Fedorova TN, Akkuratov EE

Biochemistry Mosc. 83 (2) 140-151 [2018-02-00; online 2018-04-06]

Affiliated researcher

PubMed DOI Crossref

Asian horses deepen the MSY phylogeny.

Felkel S, Vogl C, Rigler D, ..., Brem G, Wallner B

Anim. Genet. 49 (1) 90-93 [2018-02-00; online 2018-01-15]

Affiliated researcher

DOI Crossref

Archaeal community changes in Lateglacial lake sediments: Evidence from ancient DNA

Ahmed E, Parducci L, Unneberg P, ..., Slotte T, Wohlfarth B

Quaternary Science Reviews 181 (-) 19-29 [2018-02-00; online 2018-02-00]

Affiliated researcher SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

A DNA methylation biomarker of alcohol consumption.

Liu C, Marioni RE, Hedman ÅK, ..., Ingelsson E, Levy D

Mol. Psychiatry 23 (2) 422-433 [2018-02-00; online 2016-11-15]

Affiliated researcher

PubMed DOI Crossref

Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control.

Garg N, Hansson A, Knych HK, ..., Hedeland M, Globisch D

Org. Biomol. Chem. 16 (5) 698-702 [2018-01-31; online 2018-01-11]

Affiliated researcher Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Driving Protein Conformational Changes with Light: Photoinduced Structural Rearrangement in a Heterobimetallic Oxidase.

Maugeri PT, Griese JJ, Branca RM, ..., Högbom M, Shafaat HS

J. Am. Chem. Soc. 140 (4) 1471-1480 [2018-01-31; online 2018-01-22]

Affiliated researcher

PubMed DOI Crossref

Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound.

Islam MK, Strand M, Saleeb M, ..., Elofsson M, Evander M

Sci Rep 8 (1) 1925 [2018-01-31; online 2018-01-31]

Affiliated researcher

PubMed DOI Crossref

A Single Bout of Electroacupuncture Remodels Epigenetic and Transcriptional Changes in Adipose Tissue in Polycystic Ovary Syndrome.

Kokosar M, Benrick A, Perfilyev A, ..., Ling C, Stener-Victorin E

Sci Rep 8 (1) 1878 [2018-01-30; online 2018-01-30]

Affiliated researcher

PubMed DOI Crossref

Patterns of variation in cis-regulatory regions: examining evidence of purifying selection.

Naidoo T, Sjödin P, Schlebusch C, Jakobsson M

BMC Genomics 19 (1) 95 [2018-01-26; online 2018-01-26]

Affiliated researcher

PubMed DOI Crossref

Undecidability and Irreducibility Conditions for Open-Ended Evolution and Emergence.

Hernández-Orozco S, Hernández-Quiroz F, Zenil H

Artif. Life 24 (1) 56-70 [2018-01-25; online 2018-01-25]

Affiliated researcher

PubMed DOI Crossref

Metabolome dynamics of diapause in the butterfly

Lehmann P, Pruisscher P, Koštál V, ..., Wheat CW, Gotthard K

J. Exp. Biol. 221 (Pt 2) - [2018-01-25; online 2018-01-25]

Affiliated researcher

PubMed DOI Crossref

The Charlson Comorbidity Index in Registry-based Research.

Brusselaers N, Lagergren J

Methods Inf Med 56 (5) 401-406 [2018-01-24; online 2018-01-24]

Affiliated researcher

PubMed DOI Crossref

Broad Views of Non-alcoholic Fatty Liver Disease.

Mardinoglu A, Uhlen M, Borén J

Cell Systems 6 (1) 7-9 [2018-01-24; online 2018-02-06]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Demography and mating system shape the genome-wide impact of purifying selection in Arabis alpina.

Laenen B, Tedder A, Nowak MD, ..., Coupland G, Slotte T

Proc. Natl. Acad. Sci. U.S.A. 115 (4) 816-821 [2018-01-23; online 2018-01-04]

Affiliated researcher SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

A caspase-2-RFXANK interaction and its implication for MHC class II expression.

Forsberg J, Li X, Akpinar B, ..., Zhivotovsky B, Olsson M

Cell Death Dis 9 (2) 80 [2018-01-23; online 2018-01-23]

Affiliated researcher

PubMed DOI Crossref

Translational study reveals a two-faced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification.

Karnevi E, Dror LB, Mardinoglu A, ..., Uhlén M, Jirström K

Oncotarget 9 (5) 6188-6200 [2018-01-19; online 2017-12-15]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Consequences of Epithelial Inflammasome Activation by Bacterial Pathogens.

Sellin ME, Müller AA, Hardt WD

J. Mol. Biol. 430 (2) 193-206 [2018-01-19; online 2017-04-25]

Affiliated researcher Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.

Page BDG, Valerie NCK, Wright RHG, ..., Beato M, Helleday T

Nat Commun 9 (1) 250 [2018-01-17; online 2018-01-17]

Affiliated researcher

PubMed DOI Crossref

Light-activatable prodrugs based on hyaluronic acid biomaterials.

Ossipov DA, Romero AB, Ossipova E

Carbohydr Polym 180 (-) 145-155 [2018-01-15; online 2017-10-06]

Affiliated researcher

PubMed DOI Crossref

Intelligent image-based in situ single-cell isolation.

Brasko C, Smith K, Molnar C, ..., Tamas G, Horvath P

Nat Commun 9 (1) 226 [2018-01-15; online 2018-01-15]

Affiliated researcher

PubMed DOI Crossref

Increased Expression of GLP-1R in Proliferating Islets of Men1 Mice is Detectable by [68Ga]Ga-DO3A-VS-Cys40-Exendin-4 /PET.

Monazzam A, Lau J, Velikyan I, ..., Eriksson O, Skogseid B

Sci Rep 8 (1) 748 [2018-01-15; online 2018-01-15]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications.

Nassa G, Giurato G, Cimmino G, ..., Weisz A, Tarallo R

Sci Rep 8 (1) 498 [2018-01-11; online 2018-01-11]

Affiliated researcher

PubMed DOI Crossref

Impacts of feeding preweaned calves milk containing drug residues on the functional profile of the fecal microbiota.

Pereira RVV, Carroll LM, Lima S, ..., Bicalho RC, Warnick LD

Sci Rep 8 (1) 554 [2018-01-11; online 2018-01-11]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Genetic factors have a major effect on growth, number of vertebrae and otolith shape in Atlantic herring (Clupea harengus).

Berg F, Almeland OW, Skadal J, ..., Andersson L, Folkvord A

PLoS ONE 13 (1) e0190995 [2018-01-11; online 2018-01-11]

Affiliated researcher

PubMed DOI Crossref

Citrullinated histone H3 as a novel prognostic blood marker in patients with advanced cancer.

Thålin C, Lundström S, Seignez C, ..., Wallén H, Demers M

PLoS ONE 13 (1) e0191231 [2018-01-11; online 2018-01-11]

Affiliated researcher

PubMed DOI Crossref

Intersubband Quantum Disc-in-Nanowire Photodetectors with Normal-Incidence Response in the Long-Wavelength Infrared.

Karimi M, Heurlin M, Limpert S, ..., Borgström MT, Pettersson H

Nano Lett. 18 (1) 365-372 [2018-01-10; online 2017-12-27]

Affiliated researcher

PubMed DOI Crossref

Differences in Expansion Potential of Naive Chimeric Antigen Receptor T Cells from Healthy Donors and Untreated Chronic Lymphocytic Leukemia Patients.

Hoffmann JM, Schubert ML, Wang L, ..., Dreger P, Schmitt M

Front Immunol 8 (-) 1956 [2018-01-10; online 2018-01-10]

Affiliated researcher

PubMed DOI Crossref

A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.

Komseli ES, Pateras IS, Krejsgaard T, ..., Bartek J, Gorgoulis VG

BMC Genomics 19 (1) 37 [2018-01-10; online 2018-01-10]

Affiliated researcher

PubMed DOI Crossref

The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity.

Lynch CJ, Bernad R, Calvo I, ..., Munoz J, Serrano M

Cell Reports 22 (2) 396-410 [2018-01-09; online 2018-01-11]

Affiliated researcher

PubMed DOI Crossref

TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling.

Kawasaki N, Isogaya K, Dan S, ..., Miyazono K, Koinuma D

Cell Discov 4 (-) 1 [2018-01-09; online 2018-01-09]

Affiliated researcher

PubMed DOI Crossref

Polysome-profiling in small tissue samples.

Liang S, Bellato HM, Lorent J, ..., Hajj GNM, Larsson O

Nucleic Acids Res. 46 (1) e3 [2018-01-09; online 2017-10-27]

Affiliated researcher

PubMed DOI Crossref

Inference of Calmodulin's Ca2+-Dependent Free Energy Landscapes via Gaussian Mixture Model Validation.

Westerlund AM, Harpole TJ, Blau C, Delemotte L

J Chem Theory Comput 14 (1) 63-71 [2018-01-09; online 2017-12-06]

Affiliated researcher Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Ancient polymorphisms and divergence hitchhiking contribute to genomic islands of divergence within a poplar species complex.

Ma T, Wang K, Hu Q, ..., Nevo E, Liu J

Proc. Natl. Acad. Sci. U.S.A. 115 (2) E236-E243 [2018-01-09; online 2017-12-26]

Affiliated researcher

PubMed DOI Crossref

Taxonomic annotation of public fungal ITS sequences from the built environment - a report from an April 10-11, 2017 workshop (Aberdeen, UK).

Nilsson RH, Taylor AFS, Adams RI, ..., Kõljalg U, Abarenkov K

MycoKeys - (28) 65-82 [2018-01-08; online 2018-01-08]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Discovering viral genomes in human metagenomic data by predicting unknown protein families.

Barrientos-Somarribas M, Messina DN, Pou C, ..., Andersson B, Sonnhammer ELL

Sci Rep 8 (1) 28 [2018-01-08; online 2018-01-08]

Affiliated researcher

PubMed DOI Crossref

TCSBN: a database of tissue and cancer specific biological networks.

Lee S, Zhang C, Arif M, ..., Uhlen M, Mardinoglu A

Nucleic Acids Res. 46 (D1) D595-D600 [2018-01-04; online 2017-10-27]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells.

Kundu S, Ali MA, Handin N, ..., Hellström M, Sjöblom T

Genome Med 10 (1) 2 [2018-01-04; online 2018-01-04]

Affiliated researcher

PubMed DOI Crossref

Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy.

Richter KN, Revelo NH, Seitz KJ, ..., Zapiec B, Rizzoli SO

EMBO J. 37 (1) 139-159 [2018-01-04; online 2017-11-16]

Affiliated researcher Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development.

Nielsen JB, Fritsche LG, Zhou W, ..., Hveem K, Willer CJ

Am. J. Hum. Genet. 102 (1) 103-115 [2018-01-04; online 2017-12-28]

Affiliated researcher

PubMed DOI Crossref

FunCoup 4: new species, data, and visualization.

Ogris C, Guala D, Sonnhammer ELL

Nucleic Acids Res. 46 (D1) D601-D607 [2018-01-04; online 2017-11-23]

Affiliated researcher

PubMed DOI Crossref

TGF-β Family Signaling in Epithelial Differentiation and Epithelial-Mesenchymal Transition.

Kahata K, Dadras MS, Moustakas A

Cold Spring Harbor Perspectives in Biology 10 (1) - [2018-01-02; online 2018-01-02]

Affiliated researcher

PubMed DOI Crossref

SMLocalizer, a GPU accelerated ImageJ plugin for single molecule localization microscopy.

Bernhem K, Brismar H

Bioinformatics 34 (1) 137-138 [2018-01-01; online 2017-10-03]

Affiliated researcher

PubMed DOI Crossref

Environmental factors influencing the development and spread of antibiotic resistance.

Bengtsson-Palme J, Kristiansson E, Larsson DGJ

FEMS Microbiol Rev 42 (1) - [2018-01-01; online 2017-10-27]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Enhancer transcription: what, where, when, and why?

Tippens ND, Vihervaara A, Lis JT

Genes Dev. 32 (1) 1-3 [2018-01-01; online 2018-02-15]

Anniina Vihervaara SciLifeLab Fellow

PubMed DOI Crossref

Elevated Proportions of Deleterious Genetic Variation in Domestic Animals and Plants.

Makino T, Rubin CJ, Carneiro M, ..., Andersson L, Webster MT

Genome Biol Evol 10 (1) 276-290 [2018-01-01; online 2018-01-13]

Affiliated researcher

PubMed DOI Crossref

Cytokine Autoantibody Screening in the Swedish Addison Registry Identifies Patients With Undiagnosed APS1.

Eriksson D, Dalin F, Eriksson GN, ..., Bensing S, Kämpe O

J. Clin. Endocrinol. Metab. 103 (1) 179-186 [2018-01-01; online 2017-10-27]

Affiliated researcher

PubMed DOI Crossref

Computational pan-genomics: status, promises and challenges.

Computational Pan-Genomics Consortium

Brief. Bioinformatics 19 (1) 118-135 [2018-01-01; online 2016-10-23]

Affiliated researcher

PubMed DOI Crossref

Vitamin D downregulates the IL-23 receptor pathway in human mucosal group 3 innate lymphoid cells.

Konya V, Czarnewski P, Forkel M, ..., Bergman P, Mjösberg J

J. Allergy Clin. Immunol. 141 (1) 279-292 [2018-01-00; online 2017-04-20]

Affiliated researcher

PubMed DOI Crossref

Transcriptomics and Targeted Proteomics Analysis to Gain Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers.

Zhang W, Ambikan AT, Sperk M, ..., Sönnerborg A, Neogi U

EBioMedicine 27 (-) 40-50 [2018-01-00; online 2017-12-12]

Affiliated researcher

PubMed DOI Crossref

Thermodynamic analysis of computed pathways integrated into the metabolic networks of E. coli and Synechocystis reveals contrasting expansion potential.

Asplund-Samuelsson J, Janasch M, Hudson EP

Metab. Eng. 45 (-) 223-236 [2018-01-00; online 2017-12-24]

Affiliated researcher Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

The human protein atlas: A spatial map of the human proteome.

Thul PJ, Lindskog C

Protein Sci. 27 (1) 233-244 [2018-01-00; online 2017-10-10]

Affiliated researcher

PubMed DOI Crossref

The evolutionary fate of heterogeneous gene duplications: A precarious overdominant equilibrium between environment, sublethality and complementation.

Milesi P, Assogba BS, Atyame CM, ..., Weill M, Labbé P

Mol. Ecol. 27 (2) 493-507 [2018-01-00; online 2017-12-29]

Affiliated researcher Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

The environmental neurotoxin β-N-methylamino-l-alanine (l-BMAA) is deposited into birds' eggs.

Andersson M, Karlsson O, Brandt I

Ecotoxicology and Environmental Safety 147 (-) 720-724 [2018-01-00; online 2017-09-20]

Oskar Karlsson SciLifeLab Fellow

PubMed DOI Crossref

The association between p,p'-DDE levels and left ventricular mass is mainly mediated by obesity.

La Merrill MA, Lind PM, Salihovic S, van Bavel B, Lind L

Environ. Res. 160 (-) 541-546 [2018-01-00; online 2017-10-26]

Affiliated researcher

PubMed DOI Crossref

The SubCons webserver: A user friendly web interface for state-of-the-art subcellular localization prediction.

Salvatore M, Shu N, Elofsson A

Protein Sci. 27 (1) 195-201 [2018-01-00; online 2017-10-24]

Affiliated researcher

PubMed DOI Crossref

Single cell genomics of uncultured marine alveolates shows paraphyly of basal dinoflagellates.

Strassert JFH, Karnkowska A, Hehenberger E, ..., Santoro AE, Keeling PJ

ISME J 12 (1) 304-308 [2018-01-00; online 2017-10-10]

Affiliated researcher Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Reproducible diagnosis of chronic lymphocytic leukemia by flow cytometry: An European Research Initiative on CLL (ERIC) & European Society for Clinical Cell Analysis (ESCCA) Harmonisation project.

Rawstron AC, Kreuzer KA, Soosapilla A, ..., Ghia P, Montserrat E

Cytometry B Clin Cytom 94 (1) 121-128 [2018-01-00; online 2018-01-17]

Affiliated researcher

PubMed DOI Crossref

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Turcot V, Lu Y, Highland HM, ..., MAGIC Investigators , Understanding Society Scientific Group

Nat. Genet. 50 (1) 26-41 [2018-01-00; online 2017-12-22]

Affiliated researcher

PubMed DOI Crossref

Population genomics of Mesolithic Scandinavia: Investigating early postglacial migration routes and high-latitude adaptation.

Günther T, Malmström H, Svensson EM, ..., Götherström A, Jakobsson M

PLoS Biol. 16 (1) e2003703 [2018-01-00; online 2018-01-09]

Affiliated researcher

PubMed DOI Crossref

Personality as an intermediate phenotype for genetic dissection of alcohol use disorder.

Oreland L, Lagravinese G, Toffoletto S, ..., Robert Cloninger C, Comasco E

J Neural Transm (Vienna) 125 (1) 107-130 [2018-01-00; online 2017-01-04]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4.

Eriksson O, Korsgren O, Selvaraju RK, ..., Chimienti F, Altai M

Acta diabetologica 55 (1) 49-57 [2018-01-00; online 2017-10-24]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Neurological and neuropsychological effects of low and moderate prenatal alcohol exposure.

Comasco E, Rangmar J, Eriksson UJ, Oreland L

Acta Physiol 222 (1) e12892 [2018-01-00; online 2017-05-30]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

MicroRNA expression profiles in non‑epithelial ovarian tumors.

Chang RK, Li X, Mu N, ..., Larsson C, Lui WO

Int. J. Oncol. 52 (1) 55-66 [2018-01-00; online 2017-11-10]

Affiliated researcher

PubMed DOI Crossref

Linking T cell epitopes to a common linear B cell epitope: A targeting and adjuvant strategy to improve T cell responses.

Mangsbo SM, Fletcher EAK, van Maren WWC, ..., Ossendorp F, Drijfhout JW

Mol. Immunol. 93 (-) 115-124 [2018-01-00; online 2017-11-22]

Affiliated researcher

PubMed DOI Crossref

Letter: dose-response analysis revealed closer relationship between obesity and perioperative outcomes in patients after liver transplantation.

Liu Z, Mardinoglu A, Que S

Aliment. Pharmacol. Ther. 47 (2) 310-312 [2018-01-00; online 2017-12-22]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Involvement of platelet-derived growth factor ligands and receptors in tumorigenesis.

Heldin CH, Lennartsson J, Westermark B

J. Intern. Med. 283 (1) 16-44 [2018-01-00; online 2017-10-17]

Affiliated researcher

PubMed DOI Crossref

Homozygosity for a missense variant in COMP gene associated with severe pseudoachondroplasia.

Tariq M, Khan TN, Lundin L, ..., Dahl N, Klar J

Clin. Genet. 93 (1) 182-186 [2018-01-00; online 2017-11-21]

Affiliated researcher

PubMed DOI Crossref

Heterologous transporter expression for improved fatty alcohol secretion in yeast.

Hu Y, Zhu Z, Nielsen J, Siewers V

Metab. Eng. 45 (-) 51-58 [2018-01-00; online 2017-11-26]

Affiliated researcher

PubMed DOI Crossref

Genomic consequences of intensive inbreeding in an isolated wolf population.

Kardos M, Åkesson M, Fountain T, ..., Wikenros C, Ellegren H

Nat Ecol Evol 2 (1) 124-131 [2018-01-00; online 2017-11-20]

Affiliated researcher

PubMed DOI Crossref

Extracorporeal human whole blood in motion, as a tool to predict first-infusion reactions and mechanism-of-action of immunotherapeutics.

Fletcher EAK, Eltahir M, Lindqvist F, ..., Leja-Jarblad J, Mangsbo SM

Int. Immunopharmacol. 54 (-) 1-11 [2018-01-00; online 2017-10-27]

Affiliated researcher

PubMed DOI Crossref

Exome sequencing reveals NAA15 and PUF60 as candidate genes associated with intellectual disability.

Zhao JJ, Halvardson J, Zander CS, ..., Thuresson AC, Feuk L

Am. J. Med. Genet. B Neuropsychiatr. Genet. 177 (1) 10-20 [2018-01-00; online 2017-10-09]

Affiliated researcher

PubMed DOI Crossref

Evolution and postglacial colonization of Seewis hantavirus with Sorex araneus in Finland.

Ling J, Smura T, Tamarit D, ..., Vapalahti O, Sironen T

Infect. Genet. Evol. 57 (-) 88-97 [2018-01-00; online 2017-11-10]

Affiliated researcher

PubMed DOI Crossref

Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes.

Mardinoglu A, Gogg S, Lotta LA, ..., Laakso M, Smith U

EBioMedicine 27 (-) 151-155 [2018-01-00; online 2017-12-07]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Diversion of the long-chain acyl-ACP pool in Synechocystis to fatty alcohols through CRISPRi repression of the essential phosphate acyltransferase PlsX.

Kaczmarzyk D, Cengic I, Yao L, Hudson EP

Metab. Eng. 45 (-) 59-66 [2018-01-00; online 2017-12-02]

Affiliated researcher Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

Divergence of a Tandem Duplication of Manganese Superoxide Dismutase in Nosema bombycis.

Wang Y, Zhang R, Barandun J, ..., Vossbrinck CR, Xiang H

J. Eukaryot. Microbiol. 65 (1) 93-103 [2018-01-00; online 2017-08-07]

Jonas Barandun SciLifeLab Fellow

PubMed DOI Crossref

Clofazimine protects against Mycobacterium tuberculosis dissemination in the central nervous system following aerosol challenge in a murine model.

Baijnath S, Moodley C, Ngcobo B, ..., Pym A, Govender T

Int. J. Antimicrob. Agents 51 (1) 77-81 [2018-01-00; online 2017-08-24]

Affiliated researcher

PubMed DOI Crossref

Circulating proteins as predictors of incident heart failure in the elderly.

Stenemo M, Nowak C, Byberg L, ..., Fall T, Ärnlöv J

Eur. J. Heart Fail. 20 (1) 55-62 [2018-01-00; online 2017-10-02]

Affiliated researcher

DOI Crossref

Can branding and price of pharmaceuticals guide informed choices towards improved pollution control during manufacturing?

Bengtsson-Palme J, Gunnarsson L, Larsson DGJ

Journal of Cleaner Production 171 (-) 137-146 [2018-01-00; online 2018-01-00]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Asparaginase-like protein 1 is an independent prognostic marker in primary endometrial cancer, and is frequently lost in metastatic lesions.

Fonnes T, Berg HF, Bredholt T, ..., Tangen IL, Krakstad C

Gynecol. Oncol. 148 (1) 197-203 [2018-01-00; online 2017-10-31]

Affiliated researcher

DOI Crossref

Strategies for Taxonomic and Functional Annotation of Metagenomes

Bengtsson-Palme J

Metagenomics: Perspectives, Methods, and Applications - (-) 55-79 [2018-00-00; online 2018-00-00]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Generation of Stable Amber Suppression Cell Lines

Elsässer SJ

Methods in molecular biology (Clifton, N.J.) 1728 (-) 237-245 [2018-00-00; online 2018-02-06]

SciLifeLab Fellow Simon Elsässer

DOI Crossref

An unexpected re-arrangement of the antibiotic carbapenem core to new 1,4-diazepin-5-one scaffolds

Peters BK, Razuwika R, Samipillai M, ..., Govender T, Naicker T

RSC Adv. 8 (1) 190-193 [2018-00-00; online 2018-00-00]

Affiliated researcher

PubMed DOI Crossref

Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery.

Peta V, Tse C, Perazzo H, ..., Drug Induced Liver Injury- Groupe Hospitalier Pitié-Salpêtrière , Drug Induced Liver Group of the Injury Safer and Faster Evidence-based Translation consortium

PLoS ONE 12 (12) e0189436 [2017-12-29; online 2017-12-29]

Affiliated researcher

PubMed DOI Crossref

Systematic exploration of multiple drug binding sites.

Bálint M, Jeszenői N, Horváth I, van der Spoel D, Hetényi C

J Cheminform 9 (1) 65 [2017-12-28; online 2017-12-28]

Affiliated researcher

PubMed DOI Crossref

Normal values for calprotectin in stool samples of infants from the population-based longitudinal born into life study.

Peura S, Fall T, Almqvist C, ..., Helmersson-Karlqvist J, Larsson A

Scandinavian Journal of Clinical and Laboratory Investigation 78 (1-2) 120-124 [2017-12-28; online 2017-12-28]

Affiliated researcher Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

Vascularization and odontode structure of a dorsal ridge spine of Romundina stellina Ørvig 1975.

Jerve A, Qu Q, Sanchez S, Ahlberg PE, Haitina T

PLoS ONE 12 (12) e0189833 [2017-12-27; online 2017-12-27]

Affiliated researcher

PubMed DOI Crossref

Metabolic Models of Protein Allocation Call for the Kinetome.

Nilsson A, Nielsen J, Palsson BO

Cell Systems 5 (6) 538-541 [2017-12-27; online 2017-12-29]

Avlant Nilsson DDLS Fellow

PubMed DOI Crossref

Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models.

Fotaki G, Jin C, Kerzeli IK, ..., Yu D, Essand M

Oncoimmunology 7 (3) e1397250 [2017-12-26; online 2017-12-26]

Affiliated researcher

DOI Crossref

Fluidic trapping and optical detection of microparticles with a functional optical fiber

Etcheverry S, Russom A, Laurell F, Margulis W

Opt Express 25 (26) 33657 [2017-12-25; online 2017-12-22]

Affiliated researcher

PubMed DOI Crossref

The Next Step Forward in Ubiquitin-Specific Protease 7 Selective Inhibition.

Desroses M, Altun M

Cell Chem Biol 24 (12) 1429-1431 [2017-12-21; online 2017-12-23]

Affiliated researcher

PubMed DOI Crossref

A common missense variant of LILRB5 is associated with statin intolerance and myalgia.

K Siddiqui M, Maroteau C, Veluchamy A, ..., Palmer CNA, PREDICTION-ADR Consortium

Eur. Heart J. 38 (48) 3569-3575 [2017-12-21; online 2017-10-12]

Affiliated researcher

PubMed DOI Crossref

Novel Trimodal MALDI Imaging Mass Spectrometry (IMS3) at 10 μm Reveals Spatial Lipid and Peptide Correlates Implicated in Aβ Plaque Pathology in Alzheimer's Disease.

Kaya I, Brinet D, Michno W, ..., Blenow K, Hanrieder J

ACS Chem Neurosci 8 (12) 2778-2790 [2017-12-20; online 2017-10-04]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Membrane vesiculation induced by proteins of the dengue virus envelope studied by molecular dynamics simulations.

de Oliveira Dos Santos Soares R, Bortot LO, van der Spoel D, Caliri A

J Phys Condens Matter 29 (50) 504002 [2017-12-20; online 2017-11-11]

Affiliated researcher

PubMed DOI Crossref

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Flannick J, Fuchsberger C, Mahajan A, ..., Boehnke M, McCarthy MI

Sci Data 4 (-) 170179 [2017-12-19; online 2017-12-19]

Affiliated researcher

PubMed DOI Crossref

Common founder effects of hereditary hemochromatosis, Wilson´s disease, the long QT syndrome and autosomal recessive deafness caused by two novel mutations in the

Olsson KS, Wålinder O, Jansson U, ..., Raha-Chowdhury R, Williams R

Hereditas 154 (-) 16 [2017-12-19; online 2017-12-19]

Affiliated researcher

PubMed DOI Crossref

On-chip conductometric detection of short DNA sequences via electro-hydrodynamic aggregation.

Venzac B, Diakité ML, Herthnek D, ..., Malaquin L, Viovy JL

Analyst 143 (1) 190-199 [2017-12-18; online 2017-11-25]

Affiliated researcher

PubMed DOI Crossref

Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.

Hafstrand I, Badia-Martinez D, Josey BJ, ..., Sandalova T, Achour A

PLoS ONE 12 (12) e0189584 [2017-12-18; online 2017-12-18]

Affiliated researcher

PubMed DOI Crossref

A chemical screen identifies trifluoperazine as an inhibitor of glioblastoma growth.

Pinheiro T, Otrocka M, Seashore-Ludlow B, ..., Simon A, Kirkham M

Biochem. Biophys. Res. Commun. 494 (3-4) 477-483 [2017-12-16; online 2017-10-21]

Affiliated researcher

PubMed DOI Crossref

Insertion of the Type-I IFN Decoy Receptor B18R in a miRNA-Tagged Semliki Forest Virus Improves Oncolytic Capacity but Results in Neurotoxicity.

Sarén T, Ramachandran M, Martikainen M, Yu D

Mol Ther Oncolytics 7 (-) 67-75 [2017-12-15; online 2017-10-05]

Affiliated researcher

PubMed DOI Crossref

HiDi: an efficient reverse engineering schema for large-scale dynamic regulatory network reconstruction using adaptive differentiation.

Deng Y, Zenil H, Tegnér J, Kiani NA

Bioinformatics 33 (24) 3964-3972 [2017-12-15; online 2017-09-30]

Affiliated researcher

PubMed DOI Crossref

Gene Expression Signatures and Immunohistochemical Subtypes Add Prognostic Value to Each Other in Breast Cancer Cohorts.

Lundberg A, Lindström LS, Harrell JC, ..., Bergh J, Tobin NP

Clin. Cancer Res. 23 (24) 7512-7520 [2017-12-15; online 2017-09-29]

Arian Lundberg DDLS Fellow

PubMed DOI Crossref

Detection of phasic dopamine by D1 and D2 striatal medium spiny neurons.

Yapo C, Nair AG, Clement L, ..., Hellgren Kotaleski J, Vincent P

J. Physiol. (Lond.) 595 (24) 7451-7475 [2017-12-15; online 2017-09-02]

Affiliated researcher

PubMed DOI Crossref

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.

Skrott Z, Mistrik M, Andersen KK, ..., Deshaies RJ, Bartek J

Nature 552 (7684) 194-199 [2017-12-14; online 2017-12-06]

Affiliated researcher

PubMed DOI Crossref

Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer.

Ehteshami Bejnordi B, Veta M, Johannes van Diest P, ..., Racoceanu D, Venâncio R

JAMA 318 (22) 2199-2210 [2017-12-12; online 2017-12-14]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state.

Chen G, Abelein A, Nilsson HE, ..., Fisahn A, Johansson J

Nat Commun 8 (1) 2081 [2017-12-12; online 2017-12-12]

Affiliated researcher

PubMed DOI Crossref

The relation between Blastocystis and the intestinal microbiota in Swedish travellers.

Forsell J, Bengtsson-Palme J, Angelin M, ..., Evengård B, Granlund M

BMC Microbiol. 17 (1) 231 [2017-12-11; online 2017-12-11]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells.

Boström J, Sramkova Z, Salašová A, ..., Altun M, Andäng M

PLoS ONE 12 (12) e0188772 [2017-12-11; online 2017-12-11]

Affiliated researcher

PubMed DOI Crossref

Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition.

Solbak SMØ, Abdurakhmanov E, Vedeler A, Danielson UH

Virol. J. 14 (1) 236 [2017-12-11; online 2017-12-11]

Affiliated researcher

PubMed DOI Crossref

Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells.

Turi Z, Senkyrikova M, Mistrik M, Bartek J, Moudry P

Cell Cycle 17 (1) 92-101 [2017-12-10; online 2017-12-10]

Affiliated researcher

PubMed DOI Crossref

6S RNA plays a role in recovery from nitrogen depletion in Synechocystis sp. PCC 6803.

Heilmann B, Hakkila K, Georg J, ..., Axmann IM, Dienst D

BMC Microbiol. 17 (1) 229 [2017-12-08; online 2017-12-08]

Affiliated researcher

PubMed DOI Crossref

The role of Cdx2 as a lineage specific transcriptional repressor for pluripotent network during the first developmental cell lineage segregation.

Huang D, Guo G, Yuan P, ..., Robson P, Han X

Sci Rep 7 (1) 17156 [2017-12-07; online 2017-12-07]

Affiliated researcher

PubMed DOI Crossref

Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1.

Lehmann LC, Hewitt G, Aibara S, ..., Boulton SJ, Deindl S

Mol. Cell 68 (5) 847-859.e7 [2017-12-07; online 2017-12-09]

Affiliated researcher Emil Marklund SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Genomic and phenotypic characteristics of Swedish C. jejuni water isolates.

Nilsson A, Johansson C, Skarp A, ..., Engstrand L, Rautelin H

PLoS ONE 12 (12) e0189222 [2017-12-07; online 2017-12-07]

Affiliated researcher

PubMed DOI Crossref

A Unique ISR Program Determines Cellular Responses to Chronic Stress.

Guan BJ, van Hoef V, Jobava R, ..., Larsson O, Hatzoglou M

Mol. Cell 68 (5) 885-900.e6 [2017-12-07; online 2017-12-09]

Affiliated researcher

PubMed DOI Crossref

Purg M, Elias M, Kamerlin SCL

J. Am. Chem. Soc. 139 (48) 17533-17546 [2017-12-06; online 2017-11-21]

Affiliated researcher

PubMed DOI Crossref

Homozygous GRID2 missense mutation predicts a shift in the D-serine binding domain of GluD2 in a case with generalized brain atrophy and unusual clinical features.

Ali Z, Zulfiqar S, Klar J, ..., Baig S, Dahl N

BMC Med. Genet. 18 (1) 144 [2017-12-06; online 2017-12-06]

Affiliated researcher

PubMed DOI Crossref

The Intriguing Evolutionary Journey of Enteroinvasive

Pasqua M, Michelacci V, Di Martino ML, ..., Morabito S, Prosseda G

Front Microbiol 8 (-) 2390 [2017-12-05; online 2017-12-05]

Affiliated researcher

PubMed DOI Crossref

The Human Cell Atlas.

Regev A, Teichmann SA, Lander ES, ..., Yosef N, Human Cell Atlas Meeting Participants

Elife 6 (-) - [2017-12-05; online 2017-12-05]

Affiliated researcher

PubMed DOI Crossref

Protonation-Initiated Cyclization by a Class II Terpene Cyclase Assisted by Tunneling.

Eriksson A, Kürten C, Syrén PO

Chembiochem 18 (23) 2301-2305 [2017-12-05; online 2017-11-03]

Affiliated researcher

PubMed DOI Crossref

Transport and release of colloidal 3-mercaptopropionic acid-coated CdSe-CdS/ZnS core-multishell quantum dots in human umbilical vein endothelial cells.

Fontana JM, Yin H, Chen Y, ..., Brismar H, Fu Y

Int J Nanomedicine 12 (-) 8615-8629 [2017-12-04; online 2017-12-04]

Affiliated researcher

PubMed DOI Crossref

Quantitative Assessment of Drug Delivery to Tissues and Association with Phospholipidosis: A Case Study with Two Structurally Related Diamines in Development.

Loryan I, Hoppe E, Hansen K, ..., Will O, Hammarlund-Udenaes M

Mol. Pharm. 14 (12) 4362-4373 [2017-12-04; online 2017-11-03]

Affiliated researcher

PubMed DOI Crossref

Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method.

Plum J, Madsen CM, Teleki A, ..., Rades T, Müllertz A

Mol. Pharm. 14 (12) 4161-4169 [2017-12-04; online 2017-11-07]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

A New Lineage of Eukaryotes Illuminates Early Mitochondrial Genome Reduction.

Janouškovec J, Tikhonenkov DV, Burki F, ..., Mylnikov AP, Keeling PJ

Curr. Biol. 27 (23) 3717-3724.e5 [2017-12-04; online 2017-11-22]

Affiliated researcher Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Validating Missing Proteins in Human Sperm Cells by Targeted Mass-Spectrometry- and Antibody-based Methods.

Carapito C, Duek P, Macron C, ..., Lane L, Pineau C

J. Proteome Res. 16 (12) 4340-4351 [2017-12-01; online 2017-09-26]

Affiliated researcher

PubMed DOI Crossref

Smoking Cessation and Risk of Esophageal Cancer by Histological Type: Systematic Review and Meta-analysis.

Wang QL, Xie SH, Li WT, Lagergren J

J. Natl. Cancer Inst. 109 (12) - [2017-12-01; online 2018-06-23]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

Rational Synthesis of 2-Bromoporphyrins and 2,12-Dibromoporphyrins.

Bornhof AB, Xiong R, Borbas KE

J. Org. Chem. 82 (23) 12908-12913 [2017-12-01; online 2017-11-15]

Ruisheng Xiong SciLifeLab Fellow

PubMed DOI Crossref

Palladium(0)-Catalyzed Carbonylative One-Pot Synthesis of N-Acylguanidines.

Åkerbladh L, Schembri LS, Larhed M, Odell LR

J. Org. Chem. 82 (23) 12520-12529 [2017-12-01; online 2017-10-27]

Affiliated researcher

PubMed DOI Crossref

PAM50 Provides Prognostic Information When Applied to the Lymph Node Metastases of Advanced Breast Cancer Patients.

Tobin NP, Lundberg A, Lindström LS, ..., Hatschek T, TEX Trialists Group

Clin. Cancer Res. 23 (23) 7225-7231 [2017-12-01; online 2017-09-29]

Arian Lundberg DDLS Fellow

PubMed DOI Crossref

LTR Retrotransposons Show Low Levels of Unequal Recombination and High Rates of Intraelement Gene Conversion in Large Plant Genomes.

Cossu RM, Casola C, Giacomello S, ..., Scofield DG, Zuccolo A

Genome Biol Evol 9 (12) 3449-3462 [2017-12-01; online 2017-12-12]

Affiliated researcher

PubMed DOI Crossref

COMT genotype and non-recovery after a whiplash injury in a Northern European population.

Rydman E, Comasco E, Pettersson H, ..., Ponzer S, Ottosson C

BMC Musculoskelet Disord 18 (1) 507 [2017-12-01; online 2017-12-01]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Trends in GPCR drug discovery: new agents, targets and indications.

Hauser AS, Attwood MM, Rask-Andersen M, Schiöth HB, Gloriam DE

Nat Rev Drug Discov 16 (12) 829-842 [2017-12-00; online 2017-10-27]

Affiliated researcher

DOI Crossref

Surrogate assisted model reduction for stochastic biochemical reaction networks

Singh P, Hellander A

- - (-) - [2017-12-00; online 2017-12-00]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Scavenger Receptor A Mediates the Clearance and Immunological Screening of MDA-Modified Antigen by M2-Type Macrophages.

Warnecke A, Abele S, Musunuri S, Bergquist J, Harris RA

Neuromolecular Med. 19 (4) 463-479 [2017-12-00; online 2017-08-21]

Affiliated researcher

PubMed DOI Crossref

PLS3 Deletions Lead to Severe Spinal Osteoporosis and Disturbed Bone Matrix Mineralization.

Kämpe AJ, Costantini A, Levy-Shraga Y, ..., Grasemann C, Mäkitie O

J. Bone Miner. Res. 32 (12) 2394-2404 [2017-12-00; online 2017-09-06]

Affiliated researcher

DOI Crossref

Loss of Conservation of Graph Centralities in Reverse-engineered Transcriptional Regulatory Networks

Weishaupt H, Johansson P, Engström C, ..., Silvestrov S, Swartling FJ

Methodol Comput Appl Probab 19 (4) 1089-1105 [2017-12-00; online 2017-04-03]

Affiliated researcher

PubMed DOI Crossref

Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent.

Mdanda S, Baijnath S, Shobo A, ..., Naicker T, Govender T

Biomed. Chromatogr. 31 (12) - [2017-12-00; online 2017-07-13]

Affiliated researcher

PubMed DOI Crossref

Inflammatory infiltrates in parathyroid tumors.

Haglund F, Hallström BM, Nilsson IL, ..., Juhlin CC, Larsson C

Eur. J. Endocrinol. 177 (6) 445-453 [2017-12-00; online 2017-08-30]

Affiliated researcher

PubMed DOI Crossref

From transcriptional complexity to cellular phenotypes: Lessons from yeast.

Pelechano V

Yeast 34 (12) 475-482 [2017-12-00; online 2017-10-11]

Affiliated researcher SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Evolution of epigenetic chromatin states

Yung PYK, Elsässer SJ

Current Opinion in Chemical Biology 41 (-) 36-42 [2017-12-00; online 2017-12-00]

Affiliated researcher SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Evaluation of a Stenotrophomonas maltophilia bacteremia cluster in hematopoietic stem cell transplantation recipients using whole genome sequencing

Kampmeier S, Pillukat MH, Pettke A, ..., Idelevich EA, Mellmann A

Antimicrob Resist Infect Control 6 (1) - [2017-12-00; online 2017-11-13]

Affiliated researcher

PubMed DOI Crossref

East-West paths to unconventional computing.

Adamatzky A, Akl S, Burgin M, ..., Svozil K, Zenil H

Prog. Biophys. Mol. Biol. 131 (-) 469-493 [2017-12-00; online 2017-08-14]

Affiliated researcher

PubMed DOI Crossref

EPR Oximetry of Cetuximab-Treated Head-and-Neck Tumours in a Mouse Model.

Gustafsson H, Kale A, Dasu A, ..., Edqvist PH, Roberg K

Cell Biochem. Biophys. 75 (3-4) 299-309 [2017-12-00; online 2017-07-29]

Affiliated researcher

PubMed DOI Crossref

Cytotoxic T cells in chronic idiopathic neutropenia express restricted antigen receptors.

Mastrodemou S, Stalika E, Vardi A, ..., Papadaki HA, Stamatopoulos K

Leuk. Lymphoma 58 (12) 2926-2933 [2017-12-00; online 2017-05-23]

Affiliated researcher

DOI Crossref

Characterisation of in vitro gastrointestinal digests from low fat caprine kefir enriched with inulin

Simsek S, Sánchez-Rivera L, El SN, Karakaya S, Recio I

International Dairy Journal 75 (-) 68-74 [2017-12-00; online 2017-12-00]

Affiliated researcher

PubMed DOI Crossref

Cancer as an ecomolecular disease and a neoplastic consortium.

Ramón Y Cajal S, Capdevila C, Hernandez-Losa J, ..., Postovit LM, Topisirovic I

Biochim Biophys Acta Rev Cancer 1868 (2) 484-499 [2017-12-00; online 2017-09-23]

Affiliated researcher

PubMed DOI Crossref

Biodiversity, drug discovery, and the future of global health: Introducing the biodiversity to biomedicine consortium, a call to action.

Neergheen-Bhujun V, Awan AT, Baran Y, ..., Pešić M, Kagansky A

Journal of global health 7 (2) 020304 [2017-12-00; online 2018-01-06]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

An essential regulatory function of the DnaK chaperone dictates the decision between proliferation and maintenance in Caulobacter crescentus.

Schramm FD, Heinrich K, Thüring M, Bernhardt J, Jonas K

PLoS Genet 13 (12) e1007148 [2017-12-00; online 2017-12-27]

Affiliated researcher Kristina Jonas SciLifeLab Fellow

PubMed DOI Crossref

A female Viking warrior confirmed by genomics.

Hedenstierna-Jonson C, Kjellström A, Zachrisson T, ..., Götherström A, Storå J

Am. J. Phys. Anthropol. 164 (4) 853-860 [2017-12-00; online 2017-09-08]

Affiliated researcher

PubMed DOI Crossref

Maternal diabetes and incidence of childhood cancer - a nationwide cohort study and exploratory genetic analysis.

Deleskog A, den Hoed M, Tettamanti G, ..., Feychting M, Brooke HL

Clin Epidemiol 9 (-) 633-642 [2017-11-30; online 2017-11-30]

Affiliated researcher

PubMed DOI Crossref

A short feature vector for image matching: The Log-Polar Magnitude feature descriptor.

Matuszewski DJ, Hast A, Wählby C, Sintorn IM

PLoS ONE 12 (11) e0188496 [2017-11-30; online 2017-11-30]

Affiliated researcher

PubMed DOI Crossref

STRT-seq-2i: dual-index 5' single cell and nucleus RNA-seq on an addressable microwell array.

Hochgerner H, Lönnerberg P, Hodge R, ..., Zeisel A, Linnarsson S

Sci Rep 7 (1) 16327 [2017-11-27; online 2017-11-27]

Affiliated researcher

PubMed DOI Crossref

Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses.

Fotaki G, Jin C, Ramachandran M, ..., Yu D, Essand M

Oncoimmunology 7 (3) e1395126 [2017-11-27; online 2017-11-27]

Affiliated researcher

PubMed DOI Crossref

Cohort-specific imputation of gene expression improves prediction of warfarin dose for African Americans.

Gottlieb A, Daneshjou R, DeGorter M, ..., Montgomery SB, Altman RB

Genome Med 9 (1) 98 [2017-11-24; online 2017-11-24]

Affiliated researcher

PubMed DOI Crossref

A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes.

Wannberg J, Isaksson R, Bremberg U, ..., Hallberg M, Larhed M

Bioorg. Med. Chem. Lett. - (-) - [2017-11-24; online 2017-11-24]

Affiliated researcher

PubMed DOI Crossref

Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma.

Lauss M, Donia M, Harbst K, ..., Svane IM, Jönsson G

Nat Commun 8 (1) 1738 [2017-11-23; online 2017-11-23]

Affiliated researcher

PubMed DOI Crossref

Determinism and Contingency Shape Metabolic Complementation in an Endosymbiotic Consortium.

Ponce-de-Leon M, Tamarit D, Calle-Espinosa J, ..., Montero F, Pereto J

Front Microbiol 8 (-) 2290 [2017-11-22; online 2017-11-22]

Affiliated researcher

PubMed DOI Crossref

HDL particles incorporate into lipid bilayers - a combined AFM and single molecule fluorescence microscopy study.

Plochberger B, Röhrl C, Preiner J, ..., Stangl H, Schütz GJ

Sci Rep 7 (1) 15886 [2017-11-21; online 2017-11-21]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Dog ownership and the risk of cardiovascular disease and death - a nationwide cohort study.

Mubanga M, Byberg L, Nowak C, ..., Ingelsson E, Fall T

Sci Rep 7 (1) 15821 [2017-11-17; online 2017-11-17]

Affiliated researcher

PubMed DOI Crossref

A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family.

Carreras-Puigvert J, Zitnik M, Jemth AS, ..., Zupan B, Helleday T

Nat Commun 8 (1) 1541 [2017-11-16; online 2017-11-16]

Affiliated researcher

PubMed DOI Crossref

Interleukin-33 Promotes Recruitment of Microglia/Macrophages in Response to Traumatic Brain Injury.

Wicher G, Wallenquist U, Lei Y, ..., Nilsson G, Forsberg-Nilsson K

J. Neurotrauma 34 (22) 3173-3182 [2017-11-15; online 2017-07-21]

Affiliated researcher

PubMed DOI Crossref

Impact of N-methylation of the substance P 1-7 amide on anti-allodynic effect in mice after peripheral administration.

Skogh A, Lesniak A, Gaugaz FZ, ..., Hallberg M, Sandström A

Eur J Pharm Sci 109 (-) 533-540 [2017-11-15; online 2017-09-05]

Affiliated researcher

PubMed DOI Crossref

An exome sequencing based approach for genome-wide association studies in the dog.

Broeckx BJG, Derrien T, Mottier S, ..., Peelman L, Hitte C

Sci Rep 7 (1) 15680 [2017-11-15; online 2017-11-15]

Affiliated researcher

PubMed DOI Crossref

Systems pathology by multiplexed immunohistochemistry and whole-slide digital image analysis.

Blom S, Paavolainen L, Bychkov D, ..., Kallioniemi O, Pellinen T

Sci Rep 7 (1) 15580 [2017-11-14; online 2017-11-14]

Affiliated researcher

PubMed DOI Crossref

Human cytomegalovirus and Herpes Simplex type I virus can engage RNA polymerase I for transcription of immediate early genes.

Kostopoulou ON, Wilhelmi V, Raiss S, ..., Bartek J, Söderberg-Naucler C

Oncotarget 8 (57) 96536-96552 [2017-11-14; online 2017-10-29]

Affiliated researcher

PubMed DOI Crossref

Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.

Egaña I, Kaito H, Nitzsche A, ..., Hellström M, German Mouse Clinic Consortium

Sci Rep 7 (1) 15453 [2017-11-13; online 2017-11-13]

Affiliated researcher

PubMed DOI Crossref

Antibody Heavy Chain Variable Domains of Different Germline Gene Origins Diversify through Different Paths.

Kirik U, Persson H, Levander F, Greiff L, Ohlin M

Front Immunol 8 (-) 1433 [2017-11-13; online 2017-11-13]

Affiliated researcher

PubMed DOI Crossref

The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity.

Ernst C, Odom DT, Kutter C

Nat Commun 8 (1) 1411 [2017-11-10; online 2017-11-10]

Affiliated researcher Claudia Kutter SciLifeLab Fellow

DOI Crossref

Automatic Document Image Binarization using Bayesian Optimization

Vats E, Hast A, Singh P

- - (-) - [2017-11-10; online 2017-11-10]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Archaea and the origin of eukaryotes.

Eme L, Spang A, Lombard J, Stairs CW, Ettema TJG

Nat. Rev. Microbiol. 15 (12) 711-723 [2017-11-10; online 2017-11-11]

Affiliated researcher

PubMed DOI Crossref

Cholesterol Promotes Protein Binding by Affecting Membrane Electrostatics and Solvation Properties.

Doktorova M, Heberle FA, Kingston RL, ..., Vogt VM, Dick RA

Biophys. J. 113 (9) 2004-2015 [2017-11-07; online 2017-11-09]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Southern African ancient genomes estimate modern human divergence to 350,000 to 260,000 years ago.

Schlebusch CM, Malmström H, Günther T, ..., Lombard M, Jakobsson M

Science 358 (6363) 652-655 [2017-11-03; online 2017-09-28]

Affiliated researcher

PubMed DOI Crossref

Extending the Nonbonded Cationic Dummy Model to Account for Ion-Induced Dipole Interactions.

Liao Q, Pabis A, Strodel B, Kamerlin SCL

J Phys Chem Lett 8 (21) 5408-5414 [2017-11-02; online 2017-10-23]

Affiliated researcher

PubMed DOI Crossref

Influence of surface states on blinking characteristics of single colloidal CdSe-CdS/ZnS core-multishell quantum dot.

Xu H, Brismar H, Fu Y

J Colloid Interface Sci 505 (-) 528-536 [2017-11-01; online 2017-06-16]

Affiliated researcher

PubMed DOI Crossref

Cryo-EM reconstruction of the chlororibosome to 3.2 Å resolution within 24 h.

Forsberg BO, Aibara S, Kimanius D, ..., Lindahl E, Amunts A

IUCrJ 4 (Pt 6) 723-727 [2017-11-01; online 2017-09-22]

Affiliated researcher Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Choline transporter mutations in severe congenital myasthenic syndrome disrupt transporter localization.

Wang H, Salter CG, Refai O, ..., Cirak S, Crosby AH

Brain 140 (11) 2838-2850 [2017-11-01; online 2017-11-01]

Affiliated researcher

PubMed DOI Crossref

The role of the skin microbiome in atopic dermatitis: a systematic review.

Bjerre RD, Bandier J, Skov L, Engstrand L, Johansen JD

Br. J. Dermatol. 177 (5) 1272-1278 [2017-11-00; online 2017-11-12]

Affiliated researcher

PubMed DOI Crossref

The effect of drinking water contaminated with perfluoroalkyl substances on a 10-year longitudinal trend of plasma levels in an elderly Uppsala cohort.

Stubleski J, Salihovic S, Lind PM, ..., van Bavel B, Kärrman A

Environ. Res. 159 (-) 95-102 [2017-11-00; online 2017-08-03]

Affiliated researcher

PubMed DOI Crossref

The complete structure of the small-subunit processome.

Barandun J, Chaker-Margot M, Hunziker M, ..., Chait BT, Klinge S

Nat. Struct. Mol. Biol. 24 (11) 944-953 [2017-11-00; online 2017-09-25]

Jonas Barandun SciLifeLab Fellow

PubMed DOI Crossref

The acute effects of ultraviolet radiation on the blood transcriptome are independent of plasma 25OHD3.

Bustamante M, Hernandez-Ferrer C, Sarria Y, ..., Nieuwenhuijsen M, Young AR

Environ. Res. 159 (-) 239-248 [2017-11-00; online 2017-09-18]

Affiliated researcher Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Temporal characterization of the non-structural Adenovirus type 2 proteome and phosphoproteome using high-resolving mass spectrometry.

Källsten M, Gromova A, Zhao H, ..., Pettersson U, Lind SB

Virology 511 (-) 240-248 [2017-11-00; online 2017-09-12]

Affiliated researcher

PubMed DOI Crossref

SweGen: a whole-genome data resource of genetic variability in a cross-section of the Swedish population.

Ameur A, Dahlberg J, Olason P, ..., Magnusson PK, Gyllensten U

Eur. J. Hum. Genet. 25 (11) 1253-1260 [2017-11-00; online 2017-08-23]

Affiliated researcher

PubMed DOI Crossref

Species differences in pancreatic binding of DO3A-VS-Cys 40-Exendin4.

Eriksson O, Rosenström U, Selvaraju RK, Eriksson B, Velikyan I

Acta diabetologica 54 (11) 1039-1045 [2017-11-00; online 2017-09-11]

Olof Eriksson SciLifeLab Fellow

DOI Crossref

Precision food safety: A systems approach to food safety facilitated by genomics tools

Kovac J, Bakker Hd, Carroll LM, Wiedmann M

TrAC Trends in Analytical Chemistry 96 (-) 52-61 [2017-11-00; online 2017-11-00]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Photoluminescence of Diphenylalanine Peptide Nano/Microstructures: From Mechanisms to Applications.

Gan Z, Xu H

Macromol Rapid Commun 38 (22) - [2017-11-00; online 2017-09-13]

Affiliated researcher

PubMed DOI Crossref

Ninety-nine de novo assembled genomes from the moose (Alces alces) rumen microbiome provide new insights into microbial plant biomass degradation.

Svartström O, Alneberg J, Terrapon N, ..., Aspeborg H, Andersson AF

ISME J 11 (11) 2538-2551 [2017-11-00; online 2017-07-21]

Affiliated researcher

PubMed DOI Crossref

Medulloblastoma: experimental models and reality.

Neumann JE, Swartling FJ, Schüller U

Acta Neuropathol. 134 (5) 679-689 [2017-11-00; online 2017-07-19]

Affiliated researcher

PubMed DOI Crossref

Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation.

Strawbridge RJ, Silveira A, Hoed MD, ..., Hamsten A, IMPROVE study group

Atherosclerosis 266 (-) 196-204 [2017-11-00; online 2017-09-28]

Affiliated researcher

PubMed DOI Crossref

Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers.

Kamble PG, Gustafsson S, Pereira MJ, ..., Eriksson JW, Ingelsson E

Ups. J. Med. Sci. 122 (4) 234-242 [2017-11-00; online 2018-01-05]

Affiliated researcher

PubMed DOI Crossref

Genetic landscape and deregulated pathways in B-cell lymphoid malignancies.

Rosenquist R, Beà S, Du MQ, Nadel B, Pan-Hammarström Q

J. Intern. Med. 282 (5) 371-394 [2017-11-00; online 2017-06-20]

Affiliated researcher

PubMed DOI Crossref

Enabling the synthesis of medium chain alkanes and 1-alkenes in yeast.

Zhu Z, Zhou YJ, Kang MK, ..., Buijs NA, Nielsen J

Metab. Eng. 44 (-) 81-88 [2017-11-00; online 2017-09-20]

Affiliated researcher

PubMed DOI Crossref

Early stages in the ontogeny of small B-cell lymphomas: genetics and microenvironment.

Ghia P, Nadel B, Sander B, Stamatopoulos K, Stevenson FK

J. Intern. Med. 282 (5) 395-414 [2017-11-00; online 2017-04-10]

Affiliated researcher

DOI Crossref

Constrained multi-objective antenna design optimization using surrogates

Singh P, Rossi M, Couckuyt I, ..., Rogier H, Dhaene T

Int J Numer Model 30 (6) e2248 [2017-11-00; online 2017-05-04]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Comparison of

Opydo-Chanek M, Śladowska K, Blicharski K, ..., Niemeyer U, Mazur L

Anticancer Res. 37 (11) 6355-6361 [2017-11-00; online 2017-10-25]

Affiliated researcher

PubMed DOI Crossref

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.

Scott RA, Scott LJ, Mägi R, ..., Prokopenko I, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium

Diabetes 66 (11) 2888-2902 [2017-11-00; online 2017-05-31]

Affiliated researcher

PubMed DOI Crossref

A novel approach using long-read sequencing and ddPCR to investigate gonadal mosaicism and estimate recurrence risk in two families with developmental disorders.

Wilbe M, Gudmundsson S, Johansson J, ..., Frykholm C, Bondeson ML

Prenat. Diagn. 37 (11) 1146-1154 [2017-11-00; online 2017-10-17]

Affiliated researcher

PubMed DOI Crossref

A nonsense mutation in CEP55 defines a new locus for a Meckel-like syndrome, an autosomal recessive lethal fetal ciliopathy.

Bondeson ML, Ericson K, Gudmundsson S, ..., Frykholm C, Wilbe M

Clin. Genet. 92 (5) 510-516 [2017-11-00; online 2017-05-03]

Affiliated researcher

PubMed DOI Crossref

Vitamin and Amino Acid Auxotrophy in Anaerobic Consortia Operating under Methanogenic Conditions.

Hubalek V, Buck M, Tan B, ..., Bertilsson S, Eiler A

mSystems 2 (5) - [2017-10-31; online 2017-10-31]

Affiliated researcher

PubMed DOI Crossref

In situ metabolomic- and transcriptomic-profiling of the host-associated cyanobacteria Prochloron and Acaryochloris marina.

Behrendt L, Raina JB, Lutz A, ..., Larkum AW, Kühl M

ISME J 12 (2) 556-567 [2017-10-31; online 2017-10-31]

Lars Behrendt SciLifeLab Fellow

DOI Crossref

Different historical backgrounds determine contrasting phylogeographical patterns in two co-distributed Erica species (Ericaceae) across the Strait of Gibraltar

Gil-López MJ, Segarra-Moragues JG, Désamoré A, Laenen B, Ojeda F

- 185 (3) 359-375 [2017-10-31; online 2017-10-31]

Affiliated researcher

PubMed DOI Crossref

Maintenance therapy with proton pump inhibitors and risk of gastric cancer: a nationwide population-based cohort study in Sweden.

Brusselaers N, Wahlin K, Engstrand L, Lagergren J

BMJ Open 7 (10) e017739 [2017-10-30; online 2017-10-30]

Affiliated researcher

PubMed DOI Crossref

Thiol-ene-epoxy thermoset for low-temperature bonding to biofunctionalized microarray surfaces.

Zhou XC, Sjöberg R, Druet A, ..., Haraldsson T, Carlborg CF

Lab Chip 17 (21) 3672-3681 [2017-10-25; online 2017-10-05]

Affiliated researcher

PubMed DOI Crossref

Sex influences eQTL effects of SLE and Sjögren's syndrome-associated genetic polymorphisms.

Lindén M, Ramírez Sepúlveda JI, James T, ..., Kockum I, Wahren-Herlenius M

Biol Sex Differ 8 (1) 34 [2017-10-25; online 2017-10-25]

Affiliated researcher

PubMed DOI Crossref

Efficient protein production by yeast requires global tuning of metabolism.

Huang M, Bao J, Hallström BM, Petranovic D, Nielsen J

Nat Commun 8 (1) 1131 [2017-10-25; online 2017-10-25]

Affiliated researcher

PubMed DOI Crossref

Studying Kv Channels Function using Computational Methods.

Deyawe A, Kasimova MA, Delemotte L, Loussouarn G, Tarek M

Methods in molecular biology (Clifton, N.J.) 1684 (-) 321-341 [2017-10-24; online 2017-10-24]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Functional reconstruction of a eukaryotic-like E1/E2/(RING) E3 ubiquitylation cascade from an uncultured archaeon.

Hennell James R, Caceres EF, Escasinas A, ..., Ettema TJG, Robinson NP

Nat Commun 8 (1) 1120 [2017-10-24; online 2017-10-24]

Affiliated researcher

PubMed DOI Crossref

Structure-Guided Screening for Functionally Selective D2 Dopamine Receptor Ligands from a Virtual Chemical Library.

Männel B, Jaiteh M, Zeifman A, ..., Gmeiner P, Carlsson J

ACS chemical biology 12 (10) 2652-2661 [2017-10-20; online 2017-09-19]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS.

Ly T, Whigham A, Clarke R, ..., Wadsworth P, Lamond AI

Elife 6 (-) - [2017-10-20; online 2017-10-20]

Affiliated researcher

PubMed DOI Crossref

Development of a Bacterial Biosensor for Rapid Screening of Yeast p-Coumaric Acid Production.

Siedler S, Khatri NK, Zsohár A, ..., Sommer MOA, Joensson HN

ACS Synth. Biol. 6 (10) 1860-1869 [2017-10-20; online 2017-06-21]

Affiliated researcher

PubMed DOI Crossref

KIT signaling is dispensable for human mast cell progenitor development.

Dahlin JS, Ekoff M, Grootens J, ..., Olsson-Strömberg U, Nilsson G

Blood 130 (16) 1785-1794 [2017-10-19; online 2017-08-08]

Affiliated researcher

PubMed DOI Crossref

Genome-Wide Profiling of DNA Double-Strand Breaks by the BLESS and BLISS Methods.

Mirzazadeh R, Kallas T, Bienko M, Crosetto N

Methods in molecular biology (Clifton, N.J.) 1672 (-) 167-194 [2017-10-19; online 2017-10-19]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder.

Noh HJ, Tang R, Flannick J, ..., Karlsson EK, Lindblad-Toh K

Nat Commun 8 (1) 774 [2017-10-17; online 2017-10-17]

Affiliated researcher

PubMed DOI Crossref

In situ genotyping of a pooled strain library after characterizing complex phenotypes.

Lawson MJ, Camsund D, Larsson J, ..., Fange D, Elf J

Mol Syst Biol 13 (10) 947 [2017-10-17; online 2017-10-17]

Affiliated researcher

PubMed DOI Crossref

Glioblastoma and glioblastoma stem cells are dependent on functional MTH1.

Pudelko L, Rouhi P, Sanjiv K, ..., Helleday T, Bräutigam L

Oncotarget 8 (49) 84671-84684 [2017-10-17; online 2017-07-20]

Affiliated researcher

PubMed DOI Crossref

Proteome analysis of bronchoalveolar lavage from calves infected with bovine respiratory syncytial virus-Insights in pathogenesis and perspectives for new treatments.

Hägglund S, Blodörn K, Näslund K, ..., Pringle J, Valarcher JF

PLoS ONE 12 (10) e0186594 [2017-10-16; online 2017-10-16]

Affiliated researcher

PubMed DOI Crossref

Controlling adsorption of albumin with hyaluronan on silica surfaces and sulfonated latex particles.

Berts I, Fragneto G, Porcar L, Hellsing MS, Rennie AR

J Colloid Interface Sci 504 (-) 315-324 [2017-10-15; online 2017-05-17]

Affiliated researcher

PubMed DOI Crossref

Multiplexed ChIP-Seq Using Direct Nucleosome Barcoding: A Tool for High-Throughput Chromatin Analysis.

Chabbert CD, Adjalley SH, Steinmetz LM, Pelechano V

Methods in molecular biology (Clifton, N.J.) 1689 (-) 177-194 [2017-10-14; online 2017-10-14]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Signatures of positive selection reveal a universal role of chromatin modifiers as cancer driver genes.

Zapata L, Susak H, Drechsel O, ..., Estivill X, Ossowski S

Sci Rep 7 (1) 13124 [2017-10-13; online 2017-10-13]

Affiliated researcher Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Novel mutations in Darier disease and association to self-reported disease severity.

Leong IUS, Stuckey A, Ahanian T, Cederlöf M, Wikstrom JD

PLoS ONE 12 (10) e0186356 [2017-10-13; online 2017-10-13]

Affiliated researcher

PubMed DOI Crossref

Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface.

Flowers SA, Zieba A, Örnros J, ..., Kamali-Moghaddam M, Karlsson NG

Sci Rep 7 (1) 13149 [2017-10-13; online 2017-10-13]

Affiliated researcher

PubMed DOI Crossref

Fidelity of RNA templated end-joining by chlorella virus DNA ligase and a novel iLock assay with improved direct RNA detection accuracy.

Krzywkowski T, Nilsson M

Nucleic Acids Res. 45 (18) e161 [2017-10-13; online 2017-10-20]

Affiliated researcher

PubMed DOI Crossref

Correlations in Scattered X-Ray Laser Pulses Reveal Nanoscale Structural Features of Viruses.

Kurta RP, Donatelli JJ, Yoon CH, ..., Zwart PH, Mancuso AP

Phys. Rev. Lett. 119 (15) 158102 [2017-10-13; online 2017-10-12]

Affiliated researcher

PubMed DOI Crossref

Management of rivaroxaban- or apixaban-associated major bleeding with prothrombin complex concentrates: a cohort study.

Majeed A, Ågren A, Holmström M, ..., Frisk T, Schulman S

Blood 130 (15) 1706-1712 [2017-10-12; online 2017-08-23]

Affiliated researcher

PubMed DOI Crossref

Identification of 76 novel B1 metallo-β-lactamases through large-scale screening of genomic and metagenomic data.

Berglund F, Marathe NP, Österlund T, ..., Larsson DGJ, Kristiansson E

Microbiome 5 (1) 134 [2017-10-12; online 2017-10-12]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space.

Rudling A, Gustafsson R, Almlöf I, ..., Stenmark P, Carlsson J

J Med Chem 60 (19) 8160-8169 [2017-10-12; online 2017-10-03]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Spatial detection of fetal marker genes expressed at low level in adult human heart tissue.

Asp M, Salmén F, Ståhl PL, ..., Linde C, Lundeberg J

Sci Rep 7 (1) 12941 [2017-10-11; online 2017-10-11]

Affiliated researcher Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

Synthesis of 11C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation.

Roslin S, Brandt P, Nordeman P, ..., Odell LR, Eriksson J

Molecules 22 (10) - [2017-10-10; online 2017-10-10]

Affiliated researcher

PubMed DOI Crossref

The promise of spatial transcriptomics for neuroscience in the era of molecular cell typing.

Lein E, Borm LE, Linnarsson S

Science 358 (6359) 64-69 [2017-10-06; online 2017-10-07]

Affiliated researcher

PubMed DOI Crossref

Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns.

Enge M, Arda HE, Mignardi M, ..., Kim SK, Quake SR

Cell 171 (2) 321-330.e14 [2017-10-05; online 2017-09-28]

Affiliated researcher

PubMed DOI Crossref

Predicting Causal Relationships from Biological Data: Applying Automated Causal Discovery on Mass Cytometry Data of Human Immune Cells.

Triantafillou S, Lagani V, Heinze-Deml C, ..., Tegner J, Tsamardinos I

Sci Rep 7 (1) 12724 [2017-10-05; online 2017-10-05]

Affiliated researcher

PubMed DOI Crossref

Chromatin and Single-Cell RNA-Seq Profiling Reveal Dynamic Signaling and Metabolic Transitions during Human Spermatogonial Stem Cell Development.

Guo J, Grow EJ, Yi C, ..., Hotaling JM, Cairns BR

Cell Stem Cell 21 (4) 533-546.e6 [2017-10-05; online 2017-10-07]

Affiliated researcher

PubMed DOI Crossref

mTOR-sensitive translation: Cleared fog reveals more trees.

Masvidal L, Hulea L, Furic L, Topisirovic I, Larsson O

RNA Biol 14 (10) 1299-1305 [2017-10-03; online 2017-02-10]

Affiliated researcher

PubMed DOI Crossref

Local irradiation does not enhance the effect of immunostimulatory AdCD40L gene therapy combined with low dose cyclophosphamide in melanoma patients.

Irenaeus S, Schiza A, Mangsbo SM, ..., Loskog A, Ullenhag GJ

Oncotarget 8 (45) 78573-78587 [2017-10-03; online 2017-07-31]

Affiliated researcher

PubMed DOI Crossref

Identification and characterization of the novel colonization factor CS30 based on whole genome sequencing in enterotoxigenic Escherichia coli (ETEC).

von Mentzer A, Tobias J, Wiklund G, ..., Sjöling Å, Svennerholm AM

Sci Rep 7 (1) 12514 [2017-10-02; online 2017-10-02]

Astrid von Mentzer DDLS Fellow

PubMed DOI Crossref

Using metagenomics to investigate human and environmental resistomes.

Bengtsson-Palme J, Larsson DGJ, Kristiansson E

J Antimicrob Chemother 72 (10) 2690-2703 [2017-10-01; online 2017-07-05]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

The Role of Small RNA-Based Epigenetic Silencing for Purifying Selection on Transposable Elements in Capsella grandiflora.

Horvath R, Slotte T

Genome Biol Evol 9 (10) 2911-2920 [2017-10-01; online 2017-10-17]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

The Evolution of Dark Matter in the Mitogenome of Seed Beetles.

Sayadi A, Immonen E, Tellgren-Roth C, Arnqvist G

Genome Biol Evol 9 (10) 2697-2706 [2017-10-01; online 2017-10-20]

Affiliated researcher

PubMed DOI Crossref

Synthesis and in vitro evaluation of 5-substituted benzovesamicol analogs containing N-substituted amides as potential positron emission tomography tracers for the vesicular acetylcholine transporter.

Roslin S, De Rosa M, Deuther-Conrad W, ..., Brust P, Larhed M

Bioorg. Med. Chem. 25 (19) 5095-5106 [2017-10-01; online 2017-01-25]

Affiliated researcher

PubMed DOI Crossref

Switches in Genomic GC Content Drive Shifts of Optimal Codons under Sustained Selection on Synonymous Sites.

Sun Y, Tamarit D, Andersson SGE

Genome Biol Evol 9 (10) 2560-2579 [2017-10-01; online 2016-08-20]

Affiliated researcher

PubMed DOI Crossref

Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus

Eriksson E, Milenova I, Wenthe J, ..., Alemany R, Loskog A

Clin. Cancer Res. 23 (19) 5846-5857 [2017-10-01; online 2017-05-23]

Affiliated researcher

PubMed DOI Crossref

Extensive Type II Muscle Fiber Atrophy in Elderly Female Hip Fracture Patients.

Kramer IF, Snijders T, Smeets JSJ, ..., Poeze M, van Loon LJC

J. Gerontol. A Biol. Sci. Med. Sci. 72 (10) 1369-1375 [2017-10-01; online 2017-03-23]

Affiliated researcher

PubMed DOI Crossref

Differential Impact of Glucose Administered Intravenously and Orally on Circulating miR-375 Levels in Human Subjects

Yan X, Wang Z, Westberg-Rasmussen S, ..., Gregersen S, Poy MN

J. Clin. Endocrinol. Metab. 102 (10) 3749-3755 [2017-10-01; online 2017-07-28]

Affiliated researcher DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow

PubMed DOI Crossref

Validation of risk stratification models in acute myeloid leukemia using sequencing-based molecular profiling.

Wang M, Lindberg J, Klevebring D, ..., Lehmann S, Grönberg H

Leukemia 31 (10) 2029-2036 [2017-10-00; online 2017-02-07]

Affiliated researcher

PubMed DOI Crossref

Time to review the gold standard for genotyping vancomycin-resistant enterococci in epidemiology: Comparing whole-genome sequencing with PFGE and MLST in three suspected outbreaks in Sweden during 2013-2015.

Lytsy B, Engstrand L, Gustafsson Å, Kaden R

Infect. Genet. Evol. 54 (-) 74-80 [2017-10-00; online 2017-06-15]

Affiliated researcher

PubMed DOI Crossref

The tyrosine Y2502.39 in Frizzled 4 defines a conserved motif important for structural integrity of the receptor and recruitment of Disheveled.

Strakova K, Matricon P, Yokota C, ..., Bryja V, Schulte G

Cell. Signal. 38 (-) 85-96 [2017-10-00; online 2017-06-29]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Synthesis of 4

Åkerbladh L, Chow SY, Odell LR, Larhed M

ChemistryOpen 6 (5) 620-628 [2017-10-00; online 2017-08-16]

Affiliated researcher

PubMed DOI Crossref

Structures of the human mitochondrial ribosome in native states of assembly.

Brown A, Rathore S, Kimanius D, ..., Amunts A, Ramakrishnan V

Nat. Struct. Mol. Biol. 24 (10) 866-869 [2017-10-00; online 2017-09-11]

Affiliated researcher Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Sparse estimation of gene-gene interactions in prediction models.

Lee S, Pawitan Y, Ingelsson E, Lee Y

Stat Methods Med Res 26 (5) 2319-2332 [2017-10-00; online 2015-08-11]

Affiliated researcher

PubMed DOI Crossref

Sll1783, a monooxygenase associated with polysaccharide processing in the unicellular cyanobacterium Synechocystis PCC 6803.

Miranda H, Immerzeel P, Gerber L, ..., Mamedov F, Lindblad P

Physiol Plant 161 (2) 182-195 [2017-10-00; online 2017-06-30]

Affiliated researcher

DOI Crossref

Self-Healing Silk Fibroin-Based Hydrogel for Bone Regeneration: Dynamic Metal-Ligand Self-Assembly Approach

Shi L, Wang F, Zhu W, ..., Weng X, Ossipov DA

Adv. Funct. Mater. 27 (37) 1700591 [2017-10-00; online 2017-08-02]

Affiliated researcher

PubMed DOI Crossref

Reduced cell surface levels of GPI-linked markers in a new case with PIGG loss of function.

Zhao JJ, Halvardson J, Knaus A, ..., Thuresson AC, Feuk L

Hum. Mutat. 38 (10) 1394-1401 [2017-10-00; online 2017-06-12]

Affiliated researcher

PubMed DOI Crossref

Rediscussion on linearity between fibrosis stages and mortality risk in nonalcoholic fatty liver disease patients.

Liu Z, Que S, Mardinoglu A

Hepatology 66 (4) 1357-1358 [2017-10-00; online 2017-09-04]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

PLS3 sequencing in childhood-onset primary osteoporosis identifies two novel disease-causing variants.

Kämpe AJ, Costantini A, Mäkitie RE, ..., Jiao H, Mäkitie O

Osteoporos Int 28 (10) 3023-3032 [2017-10-00; online 2017-07-26]

Affiliated researcher

PubMed DOI Crossref

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals.

Kraja AT, Cook JP, Warren HR, ..., Howson JMM, CHARGE EXOME BP, CHD Exome+, Exome BP, GoT2D:T2DGenes Consortia, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group†

Circ Cardiovasc Genet 10 (5) - [2017-10-00; online 2017-10-17]

Affiliated researcher

DOI Crossref

Multi-objective Geometry Optimization of a Gas Cyclone Using Triple-Fidelity Co-Kriging Surrogate Models

Singh P, Couckuyt I, Elsayed K, Deschrijver D, Dhaene T

J Optim Theory Appl 175 (1) 172-193 [2017-10-00; online 2017-05-10]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Mixture effects of 30 environmental contaminants on incident metabolic syndrome-A prospective study.

Lind L, Salihovic S, Lampa E, Lind PM

Environ Int 107 (-) 8-15 [2017-10-00; online 2017-06-22]

Affiliated researcher

PubMed DOI Crossref

Menopausal hormone therapy and cancer risk: An overestimated risk?

Simin J, Tamimi R, Lagergren J, Adami HO, Brusselaers N

Eur. J. Cancer 84 (-) 60-68 [2017-10-00; online 2017-08-04]

Affiliated researcher

PubMed DOI Crossref

Maternal and female fetal testosterone levels are associated with maternal age and gestational weight gain.

Kallak TK, Hellgren C, Skalkidou A, ..., Campbell RE, Sundström Poromaa I

Eur. J. Endocrinol. 177 (4) 379-388 [2017-10-00; online 2017-07-13]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

In Vivo Analysis of the Viable Microbiota and Helicobacter pylori Transcriptome in Gastric Infection and Early Stages of Carcinogenesis.

Thorell K, Bengtsson-Palme J, Liu OH, ..., Lundin SB, Sjöling Å

Infect. Immun. 85 (10) - [2017-10-00; online 2017-09-20]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Improving the economics of NASH/NAFLD treatment through the use of systems biology.

Bosley J, Boren C, Lee S, ..., Boren J, Mardinoglu A

Drug Discov. Today 22 (10) 1532-1538 [2017-10-00; online 2017-07-20]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Immunohistochemical Characterization and Sensitivity to Human Adenovirus Serotypes 3, 5, and 11p of New Cell Lines Derived from Human Diffuse Grade II to IV Gliomas.

Niittykoski M, von Und Zu Fraunberg M, Martikainen M, ..., Jääskeläinen JE, Hinkkanen A

Transl Oncol 10 (5) 772-779 [2017-10-00; online 2017-08-04]

Affiliated researcher

PubMed DOI Crossref

Heparanase confers a growth advantage to differentiating murine embryonic stem cells, and enhances oligodendrocyte formation.

Xiong A, Kundu S, Forsberg M, ..., Li JP, Forsberg-Nilsson K

Matrix Biol. 62 (-) 92-104 [2017-10-00; online 2016-11-23]

Affiliated researcher

PubMed DOI Crossref

H1N1 vaccination in Sjögren's syndrome triggers polyclonal B cell activation and promotes autoantibody production.

Brauner S, Folkersen L, Kvarnström M, ..., Nordmark G, Wahren-Herlenius M

Ann. Rheum. Dis. 76 (10) 1755-1763 [2017-10-00; online 2017-07-31]

Affiliated researcher

PubMed DOI Crossref

Generation of induced pluripotent stem cells (ARO-iPSC1-11) from a patient with autosomal recessive osteopetrosis harboring the c.212+1G>T mutation in SNX10 gene.

Xu M, Stattin EL, Murphy M, Barry F

Stem Cell Res 24 (-) 51-54 [2017-10-00; online 2017-07-24]

Affiliated researcher

PubMed DOI Crossref

Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans.

Nylander I, Todkar A, Granholm L, ..., Nilsson KW, Comasco E

Mol. Neurobiol. 54 (8) 6225-6234 [2017-10-00; online 2016-10-05]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Effects of labial adhesion on maxillary arch dimensions and nasolabial esthetics in cleft lip and palate: a systematic review.

Thierens L, Brusselaers N, De Roo N, De Pauw G

Oral Dis 23 (7) 889-896 [2017-10-00; online 2017-01-24]

Affiliated researcher

PubMed DOI Crossref

Dynamics and heterogeneity of brain damage in multiple sclerosis.

Kotelnikova E, Kiani NA, Abad E, ..., Garcia-Ojalvo J, Villoslada P

PLoS Comput Biol 13 (10) e1005757 [2017-10-00; online 2017-10-26]

Affiliated researcher

DOI Crossref

Dual Structured Convolutional Neural Network with Feature Augmentation for Quantitative Characterization of Tissue Histology

Valkonen M, Kartasalo K, Liimatainen K, ..., Latonen L, Ruusuvuori P

- - (-) 27-35 [2017-10-00; online 2017-10-00]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Dissecting evolution and disease using comparative vertebrate genomics.

Meadows JRS, Lindblad-Toh K

Nat. Rev. Genet. 18 (10) 624-636 [2017-10-00; online 2017-07-24]

Affiliated researcher

PubMed DOI Crossref

Cetuximab sensitivity of head and neck squamous cell carcinoma xenografts is associated with treatment-induced reduction in EGFR, pEGFR, and pSrc.

Jedlinski A, Garvin S, Johansson AC, ..., Ponten F, Roberg K

J. Oral Pathol. Med. 46 (9) 717-724 [2017-10-00; online 2017-01-28]

Affiliated researcher

PubMed DOI Crossref

Breast cancer in young women and prognosis: How important are proliferation markers?

Fredholm H, Magnusson K, Lindström LS, ..., Frisell J, Fredriksson I

Eur. J. Cancer 84 (-) 278-289 [2017-10-00; online 2017-08-29]

Affiliated researcher

PubMed DOI Crossref

Bioinformatory-assisted analysis of next-generation sequencing data for precision medicine in pancreatic cancer.

Malgerud L, Lindberg J, Wirta V, ..., Grönberg H, Löhr JM

Mol Oncol 11 (10) 1413-1429 [2017-10-00; online 2017-08-08]

Affiliated researcher

PubMed DOI Crossref

Antibody Affinity Against 2009 A/H1N1 Influenza and Pandemrix Vaccine Nucleoproteins Differs Between Childhood Narcolepsy Patients and Controls.

Lind A, Freyhult E, Ramelius A, ..., Elding Larsson H, Lernmark Å

Viral Immunol. 30 (8) 590-600 [2017-10-00; online 2017-08-10]

Affiliated researcher

PubMed DOI Crossref

A drug pocket at the lipid bilayer-potassium channel interface.

Ottosson NE, Silverå Ejneby M, Wu X, ..., Lindahl E, Elinder F

Sci Adv 3 (10) e1701099 [2017-10-00; online 2017-10-25]

Affiliated researcher

PubMed DOI Crossref

Kinetics of dCas9 target search in

Jones DL, Leroy P, Unoson C, ..., Lawson MJ, Elf J

Science 357 (6358) 1420-1424 [2017-09-29; online 2017-09-28]

Affiliated researcher

PubMed DOI Crossref

Identification of the PAK4 interactome reveals PAK4 phosphorylation of N-WASP and promotion of Arp2/3-dependent actin polymerization.

Zhao M, Spiess M, Johansson HJ, ..., Lehtiö J, Strömblad S

Oncotarget 8 (44) 77061-77074 [2017-09-29; online 2017-08-18]

Affiliated researcher

PubMed DOI Crossref

A Drosophila female pheromone elicits species-specific long-range attraction via an olfactory channel with dual specificity for sex and food.

Lebreton S, Borrero-Echeverry F, Gonzalez F, ..., Becher PG, Witzgall P

BMC Biol. 15 (1) 88 [2017-09-29; online 2017-09-29]

Affiliated researcher

PubMed DOI Crossref

The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus.

Matzov D, Aibara S, Basu A, ..., Amunts A, Yonath AE

Nat Commun 8 (1) 723 [2017-09-28; online 2017-09-28]

Affiliated researcher Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Ecophysiology of Freshwater Verrucomicrobia Inferred from Metagenome-Assembled Genomes.

He S, Stevens SLR, Chan LK, ..., Malmstrom RR, McMahon KD

mSphere 2 (5) - [2017-09-27; online 2017-09-27]

Affiliated researcher

PubMed DOI Crossref

FC1000: normalized gene expression changes of systematically perturbed human cells.

Lönnstedt IM, Nelander S

Stat Appl Genet Mol Biol 16 (4) 217-242 [2017-09-26; online 2017-09-02]

Affiliated researcher

PubMed DOI Crossref

Anti-mycobacterial activity correlates with altered DNA methylation pattern in immune cells from BCG-vaccinated subjects.

Verma D, Parasa VR, Raffetseder J, ..., Netea M, Lerm M

Sci Rep 7 (1) 12305 [2017-09-26; online 2017-09-26]

Affiliated researcher

PubMed DOI Crossref

Phosphoproteomics Reveals Regulatory T Cell-Mediated DEF6 Dephosphorylation That Affects Cytokine Expression in Human Conventional T Cells.

Joshi RN, Binai NA, Marabita F, ..., Tegnér J, Schmidt A

Front Immunol 8 (-) 1163 [2017-09-25; online 2017-09-25]

Affiliated researcher

PubMed DOI Crossref

Autophagy is required for gamete differentiation in the moss Physcomitrella patens.

Sanchez-Vera V, Kenchappa CS, Landberg K, ..., Thelander M, Sundberg E

Autophagy 13 (11) 1939-1951 [2017-09-25; online 2017-09-25]

Affiliated researcher

PubMed DOI Crossref

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins.

Bulanova D, Ianevski A, Bugai A, ..., Velagapudi V, Kainov DE

Viruses 9 (10) - [2017-09-25; online 2017-09-25]

Affiliated researcher

PubMed DOI Crossref

The regulation of hydroxysteroid 17β-dehydrogenase type 1 and 2 gene expression in breast cancer cell lines by estradiol, dihydrotestosterone, microRNAs, and genes related to breast cancer.

Hilborn E, Stål O, Alexeyenko A, Jansson A

Oncotarget 8 (37) 62183-62194 [2017-09-22; online 2017-07-10]

Affiliated researcher

PubMed DOI Crossref

DESMAN: a new tool for de novo extraction of strains from metagenomes.

Quince C, Delmont TO, Raguideau S, ..., Collins G, Eren AM

Genome Biol. 18 (1) 181 [2017-09-21; online 2017-09-21]

Affiliated researcher

PubMed DOI Crossref

The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation.

Gómez-Herreros F, Margaritis T, Rodríguez-Galán O, ..., Holstege FCP, Chávez S

Nucleic Acids Res. 45 (16) 9302-9318 [2017-09-19; online 2017-06-24]

Affiliated researcher SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Polarity-Sensitive Probes for Superresolution Stimulated Emission Depletion Microscopy.

Sezgin E, Schneider F, Zilles V, ..., Klymchenko AS, Eggeling C

Biophys. J. 113 (6) 1321-1330 [2017-09-19; online 2017-07-19]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Tetrahydrobenzothiophene carboxamides: Beyond the kinase domain and into the fatty acid realm.

Llona-Minguez S, Fayezi S, Alihemmati A, ..., Piedrafita FJ, Helleday T

Bioorg. Med. Chem. Lett. 27 (18) 4462-4466 [2017-09-15; online 2017-08-05]

Affiliated researcher

PubMed DOI Crossref

Predicting accurate contacts in thousands of Pfam domain families using PconsC3.

Michel M, Skwark MJ, Menéndez Hurtado D, Ekeberg M, Elofsson A

Bioinformatics 33 (18) 2859-2866 [2017-09-15; online 2017-05-24]

Affiliated researcher

PubMed DOI Crossref

Heparin antagonizes cisplatin resistance of A2780 ovarian cancer cells by affecting the Wnt signaling pathway.

Pfankuchen DB, Baltes F, Batool T, ..., Schlesinger M, Bendas G

Oncotarget 8 (40) 67553-67566 [2017-09-15; online 2017-06-28]

Affiliated researcher

PubMed DOI Crossref

Mass Cytometry Identifies Distinct Lung CD4

Kaiser Y, Lakshmikanth T, Chen Y, ..., Achour A, Grunewald J

Front Immunol 8 (-) 1130 [2017-09-12; online 2017-09-12]

Affiliated researcher

PubMed DOI Crossref

Monitoring drug-serum protein interactions for early ADME prediction through Surface Plasmon Resonance technology.

Fabini E, Danielson UH

J Pharm Biomed Anal 144 (-) 188-194 [2017-09-10; online 2017-03-28]

Affiliated researcher

PubMed DOI Crossref

Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.

Shen X, Klarić L, Sharapov S, ..., Lauc G, Aulchenko YS

Nat Commun 8 (1) 447 [2017-09-06; online 2017-09-06]

Affiliated researcher

PubMed DOI Crossref

RNA-sequence data normalization through in silico prediction of reference genes: the bacterial response to DNA damage as case study.

Berghoff BA, Karlsson T, Källman T, Wagner EGH, Grabherr MG

BioData Min 10 (-) 30 [2017-09-05; online 2017-09-05]

Affiliated researcher

PubMed DOI Crossref

Cell-type-specific inhibition of the dendritic plateau potential in striatal spiny projection neurons.

Du K, Wu YW, Lindroos R, ..., Ding JB, Kotaleski JH

Proc. Natl. Acad. Sci. U.S.A. 114 (36) E7612-E7621 [2017-09-05; online 2017-08-21]

Affiliated researcher

PubMed DOI Crossref

Analysing Microbial Community Composition through Amplicon Sequencing: From Sampling to Hypothesis Testing.

Hugerth LW, Andersson AF

Front Microbiol 8 (-) 1561 [2017-09-04; online 2017-09-04]

Affiliated researcher DDLS Fellow Luisa Hugerth

DOI Crossref

Integrative taxonomy reveals too extensive lumping and a new species in the moss genus Amphidium (Bryophyta)

Sim-Sim M, Afonina OM, Almeida T, ..., González-Mancebo JM, Stech M

Systematics and Biodiversity 15 (5) 451-463 [2017-09-03; online 2017-01-19]

Affiliated researcher

PubMed DOI Crossref

Computational discovery and functional validation of novel fluoroquinolone resistance genes in public metagenomic data sets.

Boulund F, Berglund F, Flach CF, ..., Larsson DGJ, Kristiansson E

BMC Genomics 18 (1) 682 [2017-09-02; online 2017-09-02]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Trap

Mayor-Ruiz C, Dominguez O, Fernandez-Capetillo O

J. Mol. Biol. 429 (18) 2780-2789 [2017-09-01; online 2017-08-04]

Affiliated researcher

PubMed DOI Crossref

The Huperzia selago Shoot Tip Transcriptome Sheds New Light on the Evolution of Leaves.

Evkaikina AI, Berke L, Romanova MA, ..., Pawlowski K, Voitsekhovskaja OV

Genome Biol Evol 9 (9) 2444-2460 [2017-09-01; online 2017-09-29]

Affiliated researcher

PubMed DOI Crossref

Reference Intervals for Fecal Calprotectin in Adults Using Two Different Extraction Methods in the Uppsala-SCAPIS Cohort.

Fall T, Mandic-Havelka A, Helmersson-Karlqvist J, Sundstrom J, Larsson A

Clin. Lab. 63 (9) 1493-1496 [2017-09-01; online 2017-09-08]

Affiliated researcher

PubMed DOI Crossref

Rapid, High-Throughput Identification of Anthrax-Causing and Emetic Bacillus cereus Group Genome Assemblies via BTyper, a Computational Tool for Virulence-Based Classification of Bacillus cereus Group Isolates by Using Nucleotide Sequencing Data.

Carroll LM, Kovac J, Miller RA, Wiedmann M

Applied and environmental microbiology 83 (17) - [2017-09-01; online 2017-08-17]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Predicting allosteric mutants that increase activity of a major antibiotic resistance enzyme.

Latallo MJ, Cortina GA, Faham S, Nakamoto RK, Kasson PM

Chem Sci 8 (9) 6484-6492 [2017-09-01; online 2017-07-19]

Affiliated researcher

PubMed DOI Crossref

Multifocus structured illumination microscopy for fast volumetric super-resolution imaging.

Abrahamsson S, Blom H, Agostinho A, ..., Heintzmann R, Brismar H

Biomed Opt Express 8 (9) 4135-4140 [2017-09-01; online 2017-08-17]

Affiliated researcher

PubMed DOI Crossref

Genome-wide identification of Grainy head targets in

Yao L, Wang S, Westholm JO, ..., Lai EC, Samakovlis C

Development 144 (17) 3145-3155 [2017-09-01; online 2017-07-31]

Affiliated researcher

PubMed DOI Crossref

E-Science technologies in a workflow for personalized medicine using cancer screening as a case study.

Spjuth O, Karlsson A, Clements M, ..., Litton JE, Palmgren J

J Am Med Inform Assoc 24 (5) 950-957 [2017-09-01; online 2017-04-27]

Affiliated researcher

PubMed DOI Crossref

Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes

Xochelli A, Baliakas P, Kavakiotis I, ..., Ghia P, Stamatopoulos K

Clin. Cancer Res. 23 (17) 5292-5301 [2017-09-01; online 2017-05-23]

Affiliated researcher

PubMed DOI Crossref

Bioinspired coupled helical coils for soft tissue engineering of tubular structures - Improved mechanical behavior of tubular collagen type I templates.

Janke HP, Bohlin J, Lomme RMLM, ..., Feitz WFJ, Oosterwijk E

Acta Biomater 59 (-) 234-242 [2017-09-01; online 2017-06-27]

Affiliated researcher

PubMed DOI Crossref

Artifact reduction in the CSPAD detectors used for LCLS experiments.

Pietrini A, Nettelblad C

J Synchrotron Radiat 24 (Pt 5) 1092-1097 [2017-09-01; online 2017-08-22]

Affiliated researcher

PubMed DOI Crossref

A practical guide to build

Montero-Mendieta S, Grabherr M, Lantz H, ..., Webster MT, Vilà C

PeerJ 5 (-) e3702 [2017-09-01; online 2017-09-01]

Affiliated researcher

PubMed DOI Crossref

Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination.

Orta ML, Pastor N, Burgos-Morón E, ..., Helleday T, Mateos S

DNA Repair (Amst.) 57 (-) 116-124 [2017-09-00; online 2017-07-12]

Affiliated researcher

PubMed DOI Crossref

Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges.

Daneshjou R, Wang Y, Bromberg Y, ..., Brenner SE, Morgan AA

Hum. Mutat. 38 (9) 1182-1192 [2017-09-00; online 2017-07-07]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Vascular sprouts induce local attraction of proangiogenic neutrophils.

Christoffersson G, Lomei J, O'Callaghan P, ..., Engblom S, Phillipson M

J Leukoc Biol 102 (3) 741-751 [2017-09-00; online 2017-06-05]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases.

Ahsan M, Ek WE, Rask-Andersen M, ..., Gyllensten U, Johansson Å

PLoS Genet 13 (9) e1007005 [2017-09-00; online 2017-09-15]

Affiliated researcher

PubMed DOI Crossref

The Impact of Liposomal Formulations on the Release and Brain Delivery of Methotrexate: An In Vivo Microdialysis Study.

Hu Y, Rip J, Gaillard PJ, de Lange ECM, Hammarlund-Udenaes M

J Pharm Sci 106 (9) 2606-2613 [2017-09-00; online 2017-03-18]

Affiliated researcher

PubMed DOI Crossref

The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education.

Ganesan S, Luu TT, Chambers BJ, ..., Kadri N, Höglund P

Scand. J. Immunol. 86 (3) 135-142 [2017-09-00; online 2017-06-13]

Affiliated researcher

DOI Crossref

Quantum chemical study of regular and irregular geometries of MgO nanoclusters: Effects on magnetizability, electronic properties and physical characteristics

Manzetti S, Yakovlev A

Materials Chemistry and Physics 199 (-) 7-17 [2017-09-00; online 2017-09-00]

Affiliated researcher

PubMed DOI Crossref

Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI.

Carraro M, Minervini G, Giollo M, ..., Moult J, Tosatto SCE

Hum. Mutat. 38 (9) 1042-1050 [2017-09-00; online 2017-05-16]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Peptide retention time prediction.

Moruz L, Käll L

Mass Spectrom Rev 36 (5) 615-623 [2017-09-00; online 2016-01-22]

Affiliated researcher

PubMed DOI Crossref

PON-P and PON-P2 predictor performance in CAGI challenges: Lessons learned.

Niroula A, Vihinen M

Hum. Mutat. 38 (9) 1085-1091 [2017-09-00; online 2017-05-02]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.

Wain LV, Vaez A, Jansen R, ..., Caulfield MJ, Ehret GB

Hypertension 70 (3) e4-e19 [2017-09-00; online 2017-07-24]

Affiliated researcher

PubMed DOI Crossref

Metformin treatment significantly enhances intestinal glucose uptake in patients with type 2 diabetes: Results from a randomized clinical trial.

Koffert JP, Mikkola K, Virtanen KA, ..., Gomez MF, Nuutila P

Diabetes Res. Clin. Pract. 131 (-) 208-216 [2017-09-00; online 2017-07-20]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

Wheeler E, Leong A, Liu CT, ..., Barroso I, Meigs JB

PLoS Med. 14 (9) e1002383 [2017-09-00; online 2017-09-12]

Affiliated researcher

PubMed DOI Crossref

Genome scale metabolic modeling of cancer.

Nilsson A, Nielsen J

Metab. Eng. 43 (Pt B) 103-112 [2017-09-00; online 2016-11-04]

Avlant Nilsson DDLS Fellow

PubMed DOI Crossref

Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status.

Rask-Andersen M, Karlsson T, Ek WE, Johansson Å

PLoS Genet 13 (9) e1006977 [2017-09-00; online 2017-09-05]

Affiliated researcher

PubMed DOI Crossref

Dysregulations in circulating sphingolipids associate with disease activity indices in female patients with systemic lupus erythematosus: a cross-sectional study.

Checa A, Idborg H, Zandian A, ..., Gunnarsson I, Wheelock CE

Lupus 26 (10) 1023-1033 [2017-09-00; online 2017-01-29]

Affiliated researcher

PubMed DOI Crossref

Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors.

Kolberg M, Bruun J, Murumägi A, ..., Kallioniemi O, Lothe RA

Mol Oncol 11 (9) 1156-1171 [2017-09-00; online 2017-07-05]

Affiliated researcher

PubMed DOI Crossref

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing: 2017 Update.

Johnson JA, Caudle KE, Gong L, ..., Cavallari LH, Wadelius M

Clin. Pharmacol. Ther. 102 (3) 397-404 [2017-09-00; online 2017-04-04]

Affiliated researcher

PubMed DOI Crossref

Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification.

Ebai T, Souza de Oliveira FM, Löf L, ..., Landegren U, Kamali-Moghaddam M

Clin. Chem. 63 (9) 1497-1505 [2017-09-00; online 2017-06-30]

Affiliated researcher

PubMed DOI Crossref

An untypeable enterotoxigenic Escherichia coli represents one of the dominant types causing human disease.

Iguchi A, von Mentzer A, Kikuchi T, Thomson NR

Microb Genom 3 (9) e000121 [2017-09-00; online 2017-07-03]

Astrid von Mentzer DDLS Fellow

PubMed DOI Crossref

A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus

Olsson LM, Johansson ÅC, Gullstrand B, ..., Bengtsson AA, Holmdahl R

Ann Rheum Dis 76 (9) 1607-1613 [2017-09-00; online 2017-06-12]

Affiliated researcher

PubMed DOI Crossref

A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.

Karlgren M, Simoff I, Backlund M, ..., Oswald S, Artursson P

J Pharm Sci 106 (9) 2909-2913 [2017-09-00; online 2017-04-24]

Affiliated researcher

PubMed DOI Crossref

Silencing FLI or targeting CD13/ANPEP lead to dephosphorylation of EPHA2, a mediator of BRAF inhibitor resistance, and induce growth arrest or apoptosis in melanoma cells.

Azimi A, Tuominen R, Costa Svedman F, ..., Hansson J, Egyhazi Brage S

Cell Death Dis 8 (8) e3029 [2017-08-31; online 2017-08-31]

Affiliated researcher

PubMed DOI Crossref

Importance of N- and C-terminal residues of substance P 1-7 for alleviating allodynia in mice after peripheral administration.

Skogh A, Lesniak A, Gaugaz FZ, ..., Hallberg M, Sandström A

Eur J Pharm Sci 106 (-) 345-351 [2017-08-30; online 2017-06-03]

Affiliated researcher

PubMed DOI Crossref

Gearing up to handle the mosaic nature of life in the quest for orthologs.

Forslund K, Pereira C, Capella-Gutierrez S, ..., Dessimoz C, Lewis S

Bioinformatics - (-) - [2017-08-30; online 2017-08-30]

Affiliated researcher

PubMed DOI Crossref

Atropos: specific, sensitive, and speedy trimming of sequencing reads.

Didion JP, Martin M, Collins FS

PeerJ 5 (-) e3720 [2017-08-30; online 2017-08-30]

Affiliated researcher

PubMed DOI Crossref

Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer.

Asim M, Tarish F, Zecchini HI, ..., Neal D, Helleday T

Nat Commun 8 (1) 374 [2017-08-29; online 2017-08-29]

Affiliated researcher

PubMed DOI Crossref

Metabolic Network Analysis and Metatranscriptomics Reveal Auxotrophies and Nutrient Sources of the Cosmopolitan Freshwater Microbial Lineage acI.

Hamilton JJ, Garcia SL, Brown BS, ..., Forest KT, McMahon KD

mSystems 2 (4) - [2017-08-29; online 2017-08-29]

Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

Mass Cytometry and Topological Data Analysis Reveal Immune Parameters Associated with Complications after Allogeneic Stem Cell Transplantation.

Lakshmikanth T, Olin A, Chen Y, ..., Omazic B, Brodin P

Cell Reports 20 (9) 2238-2250 [2017-08-29; online 2017-08-31]

Affiliated researcher

PubMed DOI Crossref

A p53-dependent response limits the viability of mammalian haploid cells.

Olbrich T, Mayor-Ruiz C, Vega-Sendino M, ..., Ruiz S, Fernandez-Capetillo O

Proc. Natl. Acad. Sci. U.S.A. 114 (35) 9367-9372 [2017-08-29; online 2017-08-14]

Affiliated researcher

PubMed DOI Crossref

Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype.

Berggren O, Hagberg N, Alexsson A, ..., Rönnblom L, Eloranta ML

PLoS ONE 12 (8) e0183946 [2017-08-28; online 2017-08-28]

Affiliated researcher

PubMed DOI Crossref

The effect of the TM6SF2 E167K variant on liver steatosis and fibrosis in patients with chronic hepatitis C: a meta-analysis.

Liu Z, Que S, Zhou L, ..., Mardinoglu A, Valenti L

Sci Rep 7 (1) 9273 [2017-08-24; online 2017-08-24]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

DNA Polymerase λ Active Site Favors a Mutagenic Mispair between the Enol Form of Deoxyguanosine Triphosphate Substrate and the Keto Form of Thymidine Template: A Free Energy Perturbation Study.

Maximoff SN, Kamerlin SCL, Florián J

J Phys Chem B 121 (33) 7813-7822 [2017-08-24; online 2017-08-14]

Affiliated researcher

PubMed DOI Crossref

Cerium oxide nanoparticles inhibit differentiation of neural stem cells.

Gliga AR, Edoff K, Caputo F, ..., Ceccatelli S, Fadeel B

Sci Rep 7 (1) 9284 [2017-08-24; online 2017-08-24]

Affiliated researcher

PubMed DOI Crossref

Metabolomic Profiling of Extracellular Vesicles and Alternative Normalization Methods Reveal Enriched Metabolites and Strategies to Study Prostate Cancer-Related Changes.

Puhka M, Takatalo M, Nordberg ME, ..., Siljander PR, Af Hällström TM

Theranostics 7 (16) 3824-3841 [2017-08-23; online 2017-08-23]

Affiliated researcher

PubMed DOI Crossref

Clathrin-Independent Endocytosis Suppresses Cancer Cell Blebbing and Invasion.

Holst MR, Vidal-Quadras M, Larsson E, ..., Landström M, Lundmark R

Cell Reports 20 (8) 1893-1905 [2017-08-22; online 2017-08-24]

Affiliated researcher

PubMed DOI Crossref

Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging.

Baltekin Ö, Boucharin A, Tano E, Andersson DI, Elf J

Proc. Natl. Acad. Sci. U.S.A. 114 (34) 9170-9175 [2017-08-22; online 2017-08-08]

Affiliated researcher

PubMed DOI Crossref

PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway.

Reyhani V, Tsioumpekou M, van Wieringen T, ..., Lennartsson J, Rubin K

Sci Rep 7 (1) 8924 [2017-08-21; online 2017-08-21]

Affiliated researcher

PubMed DOI Crossref

Network analyses identify liver-specific targets for treating liver diseases.

Lee S, Zhang C, Liu Z, ..., Boren J, Mardinoglu A

Mol Syst Biol 13 (8) 938 [2017-08-21; online 2017-08-21]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Fibromodulin deficiency reduces collagen structural network but not glycosaminoglycan content in a syngeneic model of colon carcinoma.

Olsson PO, Kalamajski S, Maccarana M, Oldberg Å, Rubin K

PLoS ONE 12 (8) e0182973 [2017-08-21; online 2017-08-21]

Affiliated researcher

PubMed DOI Crossref

A pathology atlas of the human cancer transcriptome.

Uhlen M, Zhang C, Lee S, ..., Mardinoglu A, Ponten F

Science (New York, N.Y.) 357 (6352) eaan2507 [2017-08-18; online 2017-08-19]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia.

Kumar A, Kankainen M, Parsons A, ..., Mattila P, Heckman CA

BMC Genomics 18 (1) 629 [2017-08-17; online 2017-08-17]

Affiliated researcher

PubMed DOI Crossref

Transcriptional response to stress is pre-wired by promoter and enhancer architecture.

Vihervaara A, Mahat DB, Guertin MJ, ..., Lis JT, Sistonen L

Nat Commun 8 (1) 255 [2017-08-15; online 2017-08-15]

Anniina Vihervaara SciLifeLab Fellow

PubMed DOI Crossref

Tea and coffee consumption in relation to DNA methylation in four European cohorts.

Ek WE, Tobi EW, Ahsan M, ..., Johansson Å, Epigenome-Wide Association Study Consortium

Hum. Mol. Genet. 26 (16) 3221-3231 [2017-08-15; online 2017-05-24]

Affiliated researcher

PubMed DOI Crossref

SubCons: a new ensemble method for improved human subcellular localization predictions.

Salvatore M, Warholm P, Shu N, Basile W, Elofsson A

Bioinformatics 33 (16) 2464-2470 [2017-08-15; online 2017-04-14]

Affiliated researcher

PubMed DOI Crossref

ST Pipeline: an automated pipeline for spatial mapping of unique transcripts.

Navarro JF, Sjöstrand J, Salmén F, Lundeberg J, Ståhl PL

Bioinformatics 33 (16) 2591-2593 [2017-08-15; online 2017-04-12]

Affiliated researcher

PubMed DOI Crossref

Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 1: Triazoles, triazolopyrimidines, triazinoindoles, quinoline hydrazones and arylpiperazines.

Llona-Minguez S, Häggblad M, Martens U, ..., Scobie M, Helleday T

Bioorg. Med. Chem. Lett. 27 (16) 3897-3904 [2017-08-15; online 2017-06-16]

Affiliated researcher

PubMed DOI Crossref

Transcriptome sequencing in pediatric acute lymphoblastic leukemia identifies fusion genes associated with distinct DNA methylation profiles.

Marincevic-Zuniga Y, Dahlberg J, Nilsson S, ..., Nordlund J, Syvänen AC

J Hematol Oncol 10 (1) 148 [2017-08-14; online 2017-08-14]

Affiliated researcher

PubMed DOI Crossref

Genomic exploration of the diversity, ecology, and evolution of the archaeal domain of life.

Spang A, Caceres EF, Ettema TJG

Science 357 (6351) - [2017-08-11; online 2017-08-12]

Affiliated researcher

PubMed DOI Crossref

High Contrast PET Imaging of GRPR Expression in Prostate Cancer Using Cobalt-Labeled Bombesin Antagonist RM26.

Mitran B, Thisgaard H, Rosenström U, ..., Tolmachev V, Orlova A

Contrast Media Mol Imaging 2017 (-) 6873684 [2017-08-10; online 2017-08-10]

Affiliated researcher

PubMed DOI Crossref

Automated Training of Deep Convolutional Neural Networks for Cell Segmentation.

Sadanandan SK, Ranefall P, Le Guyader S, Wählby C

Sci Rep 7 (1) 7860 [2017-08-10; online 2017-08-10]

Affiliated researcher

PubMed DOI Crossref

Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling.

Petersen J, Wright SC, Rodríguez D, ..., Carlsson J, Schulte G

Nat Commun 8 (1) 226 [2017-08-09; online 2017-08-09]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Adaptive Mistranslation Accelerates the Evolution of Fluconazole Resistance and Induces Major Genomic and Gene Expression Alterations in

Weil T, Santamaría R, Lee W, ..., Berman J, Santos MAS

mSphere 2 (4) - [2017-08-09; online 2017-08-09]

Affiliated researcher

PubMed DOI Crossref

Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea.

Bowers RM, Kyrpides NC, Stepanauskas R, ..., Hugenholtz P, Woyke T

Nat. Biotechnol. 35 (8) 725-731 [2017-08-08; online 2017-08-09]

Affiliated researcher

PubMed DOI Crossref

Long-term follow-up in primary Sjögren's syndrome reveals differences in clinical presentation between female and male patients.

Ramírez Sepúlveda JI, Kvarnström M, Eriksson P, ..., Nordmark G, Wahren-Herlenius M

Biol Sex Differ 8 (1) 25 [2017-08-08; online 2017-08-08]

Affiliated researcher

PubMed DOI Crossref

Design and synthesis of theranostic antibiotic nanodrugs that display enhanced antibacterial activity and luminescence.

Xie S, Manuguri S, Proietti G, ..., Ramström O, Yan M

Proc. Natl. Acad. Sci. U.S.A. 114 (32) 8464-8469 [2017-08-08; online 2017-07-25]

Affiliated researcher

PubMed DOI Crossref

Use of Proteomics To Investigate Kidney Function Decline over 5 Years.

Carlsson AC, Ingelsson E, Sundström J, ..., Lind L, Ärnlöv J

Clin J Am Soc Nephrol 12 (8) 1226-1235 [2017-08-07; online 2017-07-21]

Affiliated researcher

PubMed DOI Crossref

The complete mitochondrial genome of the copepod Calanus glacialis.

Choquet M, Alves Monteiro HJ, Bengtsson-Palme J, Hoarau G

Mitochondrial DNA B Resour 2 (2) 506-507 [2017-08-06; online 2017-08-06]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Route to 3-Amidino Indoles via Pd(II)-Catalyzed C-H Bond Activation.

Rydfjord J, Skillinghaug B, Brandt P, Odell LR, Larhed M

Org. Lett. 19 (15) 4066-4069 [2017-08-04; online 2017-07-25]

Affiliated researcher

PubMed DOI Crossref

Improving the phenotype predictions of a yeast genome-scale metabolic model by incorporating enzymatic constraints.

Sánchez BJ, Zhang C, Nilsson A, ..., Kerkhoven EJ, Nielsen J

Mol Syst Biol 13 (8) 935 [2017-08-03; online 2017-08-03]

Affiliated researcher Avlant Nilsson

PubMed DOI Crossref

p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli.

Hall BM, Balan V, Gleiberman AS, ..., Chernova OB, Gudkov AV

Aging (Albany NY) 9 (8) 1867-1884 [2017-08-02; online 2017-08-05]

Camila Consiglio DDLS Fellow

PubMed DOI Crossref

Enzyme Architecture: Modeling the Operation of a Hydrophobic Clamp in Catalysis by Triosephosphate Isomerase.

Kulkarni YS, Liao Q, Petrović D, ..., Richard JP, Kamerlin SCL

J. Am. Chem. Soc. 139 (30) 10514-10525 [2017-08-02; online 2017-07-19]

Affiliated researcher

PubMed DOI Crossref

Elsässer et al. reply.

Elsässer SJ, Noh KM, Diaz N, Allis CD, Banaszynski LA

Nature 548 (7665) E7-E9 [2017-08-02; online 2017-08-05]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG).

Globisch D, Eubanks LM, Shirey RJ, ..., Hoerauf A, Janda KD

Bioorg. Med. Chem. Lett. 27 (15) 3436-3440 [2017-08-01; online 2017-05-29]

Affiliated researcher Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

The expression of opioid genes in non-classical reward areas depends on early life conditions and ethanol intake.

Granholm L, Todkar A, Bergman S, ..., Comasco E, Nylander I

Brain Res 1668 (-) 36-45 [2017-08-01; online 2017-05-13]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Sudden cardiac death among the young in Sweden from 2000 to 2010: an autopsy-based study.

Wisten A, Krantz P, Stattin EL

Europace 19 (8) 1327-1334 [2017-08-01; online 2017-09-07]

Affiliated researcher

PubMed DOI Crossref

Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease.

Mardinoglu A, Stančáková A, Lotta LA, ..., Langenberg C, Smith U

Cell Metab. 26 (2) 281-283 [2017-08-01; online 2017-08-03]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults.

Varga TV, Kurbasic A, Aine M, ..., Renström F, Franks PW

Int J Epidemiol 46 (4) 1211-1222 [2017-08-01; online 2016-11-20]

Affiliated researcher

DOI Crossref

Improved positioning and detectability of microparticles in droplet microfluidics using two-dimensional acoustophoresis

Ohlin M, Fornell A, Bruus H, Tenje M

J. Micromech. Microeng. 27 (8) 084002 [2017-08-01; online 2017-07-20]

Affiliated researcher

PubMed DOI Crossref

Gene Duplication Leads to Altered Membrane Topology of a Cytochrome P450 Enzyme in Seed Plants.

Renault H, De Marothy M, Jonasson G, ..., von Heijne G, Werck-Reichhart D

Mol. Biol. Evol. 34 (8) 2041-2056 [2017-08-01; online 2017-05-16]

Affiliated researcher

PubMed DOI Crossref

Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 2: Pyridone- and pyrimidinone-derived systems.

Llona-Minguez S, Häggblad M, Martens U, ..., Scobie M, Helleday T

Bioorg. Med. Chem. Lett. 27 (15) 3219-3225 [2017-08-01; online 2017-06-15]

Affiliated researcher

PubMed DOI Crossref

Comparison of four DNA extraction methods for comprehensive assessment of 16S rRNA bacterial diversity in marine biofilms using high-throughput sequencing.

Corcoll N, Österlund T, Sinclair L, ..., Backhaus T, Eriksson KM

FEMS Microbiol. Lett. 364 (14) - [2017-08-01; online 2017-07-05]

Affiliated researcher

PubMed DOI Crossref

With me or against me: Tumor suppressor and drug resistance activities of SAMHD1.

Herold N, Rudd SG, Sanjiv K, ..., Henter JI, Schaller T

Exp. Hematol. 52 (-) 32-39 [2017-08-00; online 2017-05-11]

Affiliated researcher

DOI Crossref

Vimentin deficiency in macrophages induces CD36-mediated inflammation

Håversen L, Ståhlman M, Mattson Hultén L, ..., Levin M, Borén J

Atherosclerosis 263 (-) e87-e88 [2017-08-00; online 2017-08-00]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

The structure of the tetanus toxin reveals pH-mediated domain dynamics.

Masuyer G, Conrad J, Stenmark P

EMBO Rep. 18 (8) 1306-1317 [2017-08-00; online 2017-06-23]

Affiliated researcher

PubMed DOI Crossref

The novel bacterial phylum Calditrichaeota is diverse, widespread and abundant in marine sediments and has the capacity to degrade detrital proteins.

Marshall IPG, Starnawski P, Cupit C, ..., Schramm A, Kjeldsen KU

Environ Microbiol Rep 9 (4) 397-403 [2017-08-00; online 2017-06-27]

Affiliated researcher

PubMed DOI Crossref

The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells.

Ramachandran M, Dimberg A, Essand M

Semin. Cancer Biol. 45 (-) 23-35 [2017-08-00; online 2017-02-28]

Affiliated researcher

PubMed DOI Crossref

The anticancer effect of mebendazole may be due to M1 monocyte/macrophage activation via ERK1/2 and TLR8-dependent inflammasome activation.

Blom K, Senkowski W, Jarvius M, ..., Nygren P, Larsson R

Immunopharmacol Immunotoxicol 39 (4) 199-210 [2017-08-00; online 2017-05-04]

Affiliated researcher

PubMed DOI Crossref

Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.

Deville C, Carroni M, Franke KB, ..., Mogk A, Saibil HR

Sci Adv 3 (8) e1701726 [2017-08-00; online 2017-08-04]

Affiliated researcher

PubMed DOI Crossref

Searching for Biosignatures in Exoplanetary Impact Ejecta.

Cataldi G, Brandeker A, Thébault P, ..., Neubeck A, Olofsson G

Astrobiology 17 (8) 721-746 [2017-08-00; online 2017-07-10]

Affiliated researcher

PubMed DOI Crossref

Replication stress, DNA damage signalling, and cytomegalovirus infection in human medulloblastomas.

Bartek J, Fornara O, Merchut-Maya JM, ..., Söderberg Naucler C, Bartkova J

Mol Oncol 11 (8) 945-964 [2017-08-00; online 2017-06-17]

Affiliated researcher

PubMed DOI Crossref

Poorly known microbial taxa dominate the microbiome of permafrost thaw ponds.

Wurzbacher C, Nilsson RH, Rautio M, Peura S

ISME J 11 (8) 1938-1941 [2017-08-00; online 2017-04-21]

Affiliated researcher Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

Objective automated quantification of fluorescence signal in histological sections of rat lens.

Talebizadeh N, Hagström NZ, Yu Z, ..., Söderberg P, Wählby C

Cytometry A 91 (8) 815-821 [2017-08-00; online 2017-05-11]

Affiliated researcher

PubMed DOI Crossref

Northeast African genomic variation shaped by the continuity of indigenous groups and Eurasian migrations.

Hollfelder N, Schlebusch CM, Günther T, ..., Hassan HY, Jakobsson M

PLoS Genet 13 (8) e1006976 [2017-08-00; online 2017-08-24]

Affiliated researcher

PubMed DOI Crossref

Multiple pathogen biomarker detection using an encoded bead array in droplet PCR.

Periyannan Rajeswari PK, Soderberg LM, Yacoub A, ..., Andersson Svahn H, Joensson HN

J. Microbiol. Methods 139 (-) 22-28 [2017-08-00; online 2017-04-20]

Affiliated researcher

PubMed DOI Crossref

Molecular composition and distribution of gap junctions in the sensory epithelium of the human cochlea-a super-resolution structured illumination microscopy (SR-SIM) study.

Liu W, Li H, Edin F, ..., Pfaller K, Rask-Andersen H

Ups. J. Med. Sci. 122 (3) 160-170 [2017-08-00; online 2017-05-17]

Affiliated researcher

PubMed DOI Crossref

Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and

Spyrou A, Kundu S, Haseeb L, ..., Vlodavsky I, Forsberg-Nilsson K

Mol. Cancer Ther. 16 (8) 1705-1716 [2017-08-00; online 2017-07-17]

Affiliated researcher

PubMed DOI Crossref

Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers.

Ward-Caviness CK, Xu T, Aspelund T, ..., Wang-Sattler R, Peters A

Heart 103 (16) 1278-1285 [2017-08-00; online 2017-03-02]

Affiliated researcher

PubMed DOI Crossref

Heterogeneous gene duplications can be adaptive because they permanently associate overdominant alleles.

Milesi P, Weill M, Lenormand T, Labbé P

Evol Lett 1 (3) 169-180 [2017-08-00; online 2017-07-21]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Genotype-covariate interaction effects and the heritability of adult body mass index.

Robinson MR, English G, Moser G, ..., Cesarini D, Visscher PM

Nat. Genet. 49 (8) 1174-1181 [2017-08-00; online 2017-07-10]

Affiliated researcher

PubMed DOI Crossref

Genomewide patterns of variation in genetic diversity are shared among populations, species and higher-order taxa.

Vijay N, Weissensteiner M, Burri R, ..., Ellegren H, Wolf JBW

Mol. Ecol. 26 (16) 4284-4295 [2017-08-00; online 2017-06-27]

Affiliated researcher

PubMed DOI Crossref

Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression.

Fedele V, Dai F, Masilamani AP, ..., Bredel M, Carro MS

Mol. Cancer Res. 15 (8) 998-1011 [2017-08-00; online 2017-05-16]

Affiliated researcher

PubMed DOI Crossref

Engineered Cpf1 variants with altered PAM specificities.

Gao L, Cox DBT, Yan WX, ..., Crosetto N, Zhang F

Nat. Biotechnol. 35 (8) 789-792 [2017-08-00; online 2017-06-05]

Affiliated researcher

PubMed DOI Crossref

Domestication rewired gene expression and nucleotide diversity patterns in tomato.

Sauvage C, Rau A, Aichholz C, ..., David J, Glémin S

Plant J. 91 (4) 631-645 [2017-08-00; online 2017-06-12]

Affiliated researcher

PubMed DOI Crossref

Comprehensive Profiling of the Androgen Receptor in Liquid Biopsies from Castration-resistant Prostate Cancer Reveals Novel Intra-AR Structural Variation and Splice Variant Expression Patterns.

De Laere B, van Dam PJ, Whitington T, ..., Grönberg H, Lindberg J

Eur. Urol. 72 (2) 192-200 [2017-08-00; online 2017-01-16]

Affiliated researcher

PubMed DOI Crossref

Comparison of cellular location and expression of Plakophilin-2 in epidermal cells from nonlesional atopic skin and healthy skin in German shepherd dogs.

Ardesjö-Lundgren B, Tengvall K, Bergvall K, ..., Lindblad-Toh K, Andersson G

Vet. Dermatol. 28 (4) 377-e88 [2017-08-00; online 2017-04-06]

Affiliated researcher

PubMed DOI Crossref

Childhood adiposity and risk of type 1 diabetes: A Mendelian randomization study.

Censin JC, Nowak C, Cooper N, ..., Todd JA, Fall T

PLoS Med. 14 (8) e1002362 [2017-08-00; online 2017-08-01]

Affiliated researcher

PubMed DOI Crossref

CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.

Gomez-Velazquez M, Badia-Careaga C, Lechuga-Vieco AV, ..., Gomez-Skarmeta JL, Manzanares M

PLoS Genet 13 (8) e1006985 [2017-08-00; online 2017-08-28]

Affiliated researcher

PubMed DOI Crossref

CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia.

Siddiqui MK, Veluchamy A, Maroteau C, ..., Palmer CNA, PREDICTION-ADR Consortium

Circ Cardiovasc Genet 10 (4) - [2017-08-00; online 2017-08-10]

Affiliated researcher

PubMed DOI Crossref

Biophysical analysis of the dynamics of calmodulin interactions with neurogranin and Ca

Seeger C, Talibov VO, Danielson UH

J. Mol. Recognit. 30 (8) - [2017-08-00; online 2017-04-27]

Affiliated researcher

PubMed DOI Crossref

Binding of canonical Wnt ligands to their receptor complexes occurs in ordered plasma membrane environments.

Sezgin E, Azbazdar Y, Ng XW, ..., Eggeling C, Ozhan G

FEBS J. 284 (15) 2513-2526 [2017-08-00; online 2017-07-06]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Allopregnanolone levels and depressive symptoms during pregnancy in relation to single nucleotide polymorphisms in the allopregnanolone synthesis pathway.

Hellgren C, Comasco E, Skalkidou A, Sundström-Poromaa I

Horm Behav 94 (-) 106-113 [2017-08-00; online 2017-07-20]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Addition of exogenous sodium palmitate increases the IAPP/insulin mRNA ratio via GPR40 in human EndoC-βH1 cells.

Krizhanovskii C, Fred RG, Oskarsson ME, Westermark GT, Welsh N

Ups. J. Med. Sci. 122 (3) 149-159 [2017-08-00; online 2017-10-05]

Affiliated researcher

PubMed DOI Crossref

A Biopsychosocial Approach to Risk and Resilience on Behavior in Children Followed from Birth to Age 12.

Agnafors S, Svedin CG, Oreland L, ..., Comasco E, Sydsjö G

Child Psychiatry Hum Dev 48 (4) 584-596 [2017-08-00; online 2016-09-16]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

A

Dumanski JP, Rasi C, Björklund P, ..., Hellman P, Tiensuu Janson E

Endocr. Relat. Cancer 24 (8) 427-443 [2017-08-00; online 2017-06-20]

Affiliated researcher

PubMed DOI Crossref

Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide.

Snapp EL, McCaul N, Quandte M, ..., Sanders RW, Braakman I

Elife 6 (-) - [2017-07-28; online 2017-07-28]

Affiliated researcher

PubMed DOI Crossref

Rapid signal enhancement method for nanoprobe-based biosensing.

Dias JT, Svedberg G, Nystrand M, Andersson-Svahn H, Gantelius J

Sci Rep 7 (1) 6837 [2017-07-28; online 2017-07-28]

Affiliated researcher

PubMed DOI Crossref

Molecular simulations and free-energy calculations suggest conformation-dependent anion binding to a cytoplasmic site as a mechanism for Na+/K+-ATPase ion selectivity.

Razavi AM, Delemotte L, Berlin JR, Carnevale V, Voelz VA

J Biol Chem 292 (30) 12412-12423 [2017-07-28; online 2017-06-06]

Affiliated researcher Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Vitamin D-deficient mice have more invasive urinary tract infection.

Hertting O, Lüthje P, Sullivan D, Aspenström P, Brauner A

PLoS ONE 12 (7) e0180810 [2017-07-27; online 2017-07-27]

Affiliated researcher

PubMed DOI Crossref

Health care workers' perceptions of point-of-care testing in a low-income country-A qualitative study in Southwestern Uganda.

Rasti R, Nanjebe D, Karlström J, ..., Boum Y, Alfvén T

PLoS ONE 12 (7) e0182005 [2017-07-27; online 2017-07-27]

Affiliated researcher

PubMed DOI Crossref

Droplet Barcode Sequencing for targeted linked-read haplotyping of single DNA molecules.

Redin D, Borgström E, He M, ..., Käller M, Ahmadian A

Nucleic Acids Res. 45 (13) e125 [2017-07-27; online 2017-05-20]

Affiliated researcher

PubMed DOI Crossref

Untargeted screening for novel autoantibodies with prognostic value in first-episode psychosis.

Zandian A, Wingård L, Nilsson H, ..., Nilsson P, Persson MAA

Transl Psychiatry 7 (7) e1177 [2017-07-25; online 2017-07-25]

Affiliated researcher

PubMed DOI Crossref

Stable membrane orientations of small dual-topology membrane proteins.

Fluman N, Tobiasson V, von Heijne G

Proc. Natl. Acad. Sci. U.S.A. 114 (30) 7987-7992 [2017-07-25; online 2017-07-11]

Affiliated researcher

PubMed DOI Crossref

Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery.

Mateus A, Gordon LJ, Wayne GJ, ..., Hann MM, Artursson P

Proc. Natl. Acad. Sci. U.S.A. 114 (30) E6231-E6239 [2017-07-25; online 2017-07-12]

Affiliated researcher

PubMed DOI Crossref

Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis.

Nilsson A, Peric A, Strimfors M, ..., Andrén PE, Hilgendorf C

Sci Rep 7 (1) 6352 [2017-07-25; online 2017-07-25]

Affiliated researcher

PubMed DOI Crossref

Fragment optimization for GPCRs by molecular dynamics free energy calculations: Probing druggable subpockets of the A 2A adenosine receptor binding site.

Matricon P, Ranganathan A, Warnick E, ..., Jacobson KA, Carlsson J

Sci Rep 7 (1) 6398 [2017-07-25; online 2017-07-25]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Continuous immunotypes describe human immune variation and predict diverse responses.

Kaczorowski KJ, Shekhar K, Nkulikiyimfura D, ..., Chakraborty AK, Brodin P

Proc. Natl. Acad. Sci. U.S.A. 114 (30) E6097-E6106 [2017-07-25; online 2017-07-10]

Affiliated researcher

PubMed DOI Crossref

Novel risk genes for systemic lupus erythematosus predicted by random forest classification.

Almlöf JC, Alexsson A, Imgenberg-Kreuz J, ..., Sandling JK, Syvänen AC

Sci Rep 7 (1) 6236 [2017-07-24; online 2017-07-24]

Affiliated researcher

DOI Crossref

Continuous Flow Synthesis under High-Temperature/High-Pressure Conditions Using a Resistively Heated Flow Reactor

Adeyemi A, Bergman J, Brånalt J, Sävmarker J, Larhed M

Org. Process Res. Dev. 21 (7) 947-955 [2017-07-21; online 2017-06-29]

Affiliated researcher

PubMed DOI Crossref

Tuning Metabolome Coverage in Reversed Phase LC-MS Metabolomics of MeOH Extracted Samples Using the Reconstitution Solvent Composition.

Lindahl A, Sääf S, Lehtiö J, Nordström A

Anal. Chem. 89 (14) 7356-7364 [2017-07-18; online 2017-06-28]

Affiliated researcher

PubMed DOI Crossref

Sex is a moderator of the association between NOS1AP sequence variants and QTc in two long QT syndrome founder populations: a pedigree-based measured genotype association analysis.

Winbo A, Stattin EL, Westin IM, ..., Jensen SM, Rydberg A

BMC Med. Genet. 18 (1) 74 [2017-07-18; online 2017-07-18]

Affiliated researcher

PubMed DOI Crossref

Effects of Detergent Micelles on Lipid Binding to Proteins in Electrospray Ionization Mass Spectrometry.

Landreh M, Costeira-Paulo J, Gault J, Marklund EG, Robinson CV

Anal. Chem. 89 (14) 7425-7430 [2017-07-18; online 2017-07-03]

Affiliated researcher

PubMed DOI Crossref

De novo active sites for resurrected Precambrian enzymes.

Risso VA, Martinez-Rodriguez S, Candel AM, ..., Gavira JA, Sanchez-Ruiz JM

Nat Commun 8 (-) 16113 [2017-07-18; online 2017-07-18]

Affiliated researcher

PubMed DOI Crossref

Transancestral mapping and genetic load in systemic lupus erythematosus.

Langefeld CD, Ainsworth HC, Cunninghame Graham DS, ..., Gaffney PM, Vyse TJ

Nat Commun 8 (-) 16021 [2017-07-17; online 2017-07-17]

Affiliated researcher

PubMed DOI Crossref

High performance micro-flow cytometer based on optical fibres.

Etcheverry S, Faridi A, Ramachandraiah H, ..., Laurell F, Russom A

Sci Rep 7 (1) 5628 [2017-07-17; online 2017-07-17]

Affiliated researcher

PubMed DOI Crossref

Yoctomole electrochemical genosensing of Ebola virus cDNA by rolling circle and circle to circle amplification.

Carinelli S, Kühnemund M, Nilsson M, Pividori MI

Biosens Bioelectron 93 (-) 65-71 [2017-07-15; online 2016-10-11]

Affiliated researcher

PubMed DOI Crossref

Large-scale structure prediction by improved contact predictions and model quality assessment.

Michel M, Menéndez Hurtado D, Uziela K, Elofsson A

Bioinformatics 33 (14) i23-i29 [2017-07-15; online 2017-09-09]

Affiliated researcher

PubMed

Fully automated GMP production of [68Ga]Ga-DO3A-VS-Cys40-Exendin-4 for clinical use.

Velikyan I, Rosenstrom U, Eriksson O

American journal of nuclear medicine and molecular imaging 7 (3) 111-125 [2017-07-15; online 2017-07-15]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Does antifouling paint select for antibiotic resistance?

Flach CF, Pal C, Svensson CJ, ..., Tysklind M, Larsson DGJ

Sci. Total Environ. 590-591 (-) 461-468 [2017-07-15; online 2017-03-08]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Combined PET and microdialysis for in vivo estimation of drug blood-brain barrier transport and brain unbound concentrations.

Gustafsson S, Eriksson J, Syvänen S, ..., Hammarlund-Udenaes M, Antoni G

NeuroImage 155 (-) 177-186 [2017-07-15; online 2017-04-30]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Selection of complementary foods based on optimal nutritional values.

Sen P, Mardinogulu A, Nielsen J

Sci Rep 7 (1) 5413 [2017-07-14; online 2017-07-14]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.

Jaiswal H, Benada J, Müllers E, ..., Macurek L, Lindqvist A

EMBO J. 36 (14) 2161-2176 [2017-07-14; online 2017-06-12]

Affiliated researcher

PubMed DOI Crossref

A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.

Malenczyk K, Girach F, Szodorai E, ..., Groop L, Harkany T

EMBO J. 36 (14) 2107-2125 [2017-07-14; online 2017-06-21]

Affiliated researcher

PubMed DOI Crossref

Super-resolution optical microscopy for studying membrane structure and dynamics.

Sezgin E

J Phys Condens Matter 29 (27) 273001 [2017-07-12; online 2017-05-08]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

New Challenges to Study Heterogeneity in Cancer Redox Metabolism.

Benfeitas R, Uhlen M, Nielsen J, Mardinoglu A

Front Cell Dev Biol 5 (-) 65 [2017-07-11; online 2017-07-11]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway.

Salašová A, Yokota C, Potěšil D, ..., Bryja V, Arenas E

Mol Neurodegener 12 (1) 54 [2017-07-11; online 2017-07-11]

Affiliated researcher

PubMed DOI Crossref

Y Chromosome Uncovers the Recent Oriental Origin of Modern Stallions.

Wallner B, Palmieri N, Vogl C, ..., Schlötterer C, Brem G

Curr. Biol. 27 (13) 2029-2035.e5 [2017-07-10; online 2017-06-29]

Affiliated researcher

PubMed DOI Crossref

The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization.

Alam MT, Olin-Sandoval V, Stincone A, ..., Luisi BF, Ralser M

Nat Commun 8 (-) 16018 [2017-07-10; online 2017-07-10]

Aleksej Zelezniak SciLifeLab Fellow

PubMed DOI Crossref

eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences.

Pelechano V, Alepuz P

Nucleic Acids Res. 45 (12) 7326-7338 [2017-07-07; online 2017-05-27]

Affiliated researcher SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Polyplex Evolution: Understanding Biology, Optimizing Performance.

Hall A, Lächelt U, Bartek J, Wagner E, Moghimi SM

Mol. Ther. 25 (7) 1476-1490 [2017-07-05; online 2017-03-06]

Affiliated researcher

PubMed DOI Crossref

Physico-Pathologic Mechanisms Involved in Neurodegeneration: Misfolded Protein-Plasma Membrane Interactions.

Shrivastava AN, Aperia A, Melki R, Triller A

Neuron 95 (1) 33-50 [2017-07-05; online 2017-07-07]

Affiliated researcher

PubMed DOI Crossref

Analysis of IAV Replication and Co-infection Dynamics by a Versatile RNA Viral Genome Labeling Method.

Dou D, Hernández-Neuta I, Wang H, ..., Nilsson M, Daniels R

Cell Reports 20 (1) 251-263 [2017-07-05; online 2017-07-07]

Affiliated researcher

PubMed DOI Crossref

TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α.

Hamidi A, Song J, Thakur N, ..., Heldin CH, Landström M

Sci Signal 10 (486) - [2017-07-04; online 2017-07-04]

Affiliated researcher

PubMed DOI Crossref

SCENERY: a web application for (causal) network reconstruction from cytometry data.

Papoutsoglou G, Athineou G, Lagani V, ..., Tegnér J, Tsamardinos I

Nucleic Acids Res. 45 (W1) W270-W275 [2017-07-03; online 2017-05-20]

Affiliated researcher

DOI Crossref

Mineral Type Structures Soil Microbial Communities

Ahmed E, Hugerth LW, Logue JB, ..., Andersson AF, Holmström SJM

Geomicrobiology Journal 34 (6) 538-545 [2017-07-03; online 2016-11-22]

Affiliated researcher DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Isoelectric point-based fractionation by HiRIEF coupled to LC-MS allows for in-depth quantitative analysis of the phosphoproteome.

Panizza E, Branca RMM, Oliviusson P, Orre LM, Lehtiö J

Sci Rep 7 (1) 4513 [2017-07-03; online 2017-07-03]

Affiliated researcher

PubMed DOI Crossref

Structure-metabolism-relationships in the microsomal clearance of piperazin-1-ylpyridazines.

Llona-Minguez S, Ghassemian A, Baranczewski P, ..., Scobie M, Helleday T

Med. Chem. Commun. 8 (7) 1553-1560 [2017-07-01; online 2017-07-04]

Affiliated researcher

PubMed DOI Crossref

Fabrication of user-friendly and biomimetic 1,1'-carbonyldiimidazole cross-linked gelatin/agar microfluidic devices.

Jocic S, Mestres G, Tenje M

Mater Sci Eng C Mater Biol Appl 76 (-) 1175-1180 [2017-07-01; online 2017-03-06]

Affiliated researcher

PubMed DOI Crossref

Effects of alternative electron acceptors on the activity and community structure of methane-producing and consuming microbes in the sediments of two shallow boreal lakes.

Rissanen AJ, Karvinen A, Nykänen H, ..., Mäki A, Kankaala P

FEMS Microbiol. Ecol. 93 (7) - [2017-07-01; online 2017-06-24]

Affiliated researcher Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

Dog Exposure During the First Year of Life and Type 1 Diabetes in Childhood.

Wernroth ML, Svennblad B, Fall K, ..., Almqvist C, Fall T

JAMA Pediatr 171 (7) 663-669 [2017-07-01; online 2017-05-02]

Affiliated researcher

PubMed DOI Crossref

Toward molecular imaging of the free fatty acid receptor 1.

Hellström-Lindahl E, Åberg O, Ericsson C, ..., Skrtic S, Eriksson O

Acta diabetologica 54 (7) 663-668 [2017-07-00; online 2017-04-13]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Stability of Proteins in Dried Blood Spot Biobanks.

Björkesten J, Enroth S, Shen Q, ..., Kamali-Moghaddam M, Landegren U

Mol. Cell Proteomics 16 (7) 1286-1296 [2017-07-00; online 2017-05-13]

Affiliated researcher

PubMed DOI Crossref

Numerous Ontogenetic Roads to Mantle Cell Lymphoma: Immunogenetic and Immunohistochemical Evidence.

Pouliou E, Xochelli A, Kanellis G, ..., Stamatopoulos K, Papadaki T

Am. J. Pathol. 187 (7) 1454-1458 [2017-07-00; online 2017-04-28]

Affiliated researcher

PubMed DOI Crossref

Monoclonal B-cell lymphocytosis in a hospital-based UK population and a rural Ugandan population: a cross-sectional study.

Rawstron AC, Ssemaganda A, de Tute R, ..., Asiki G, Newton R

Lancet Haematol 4 (7) e334-e340 [2017-07-00; online 2017-07-03]

Affiliated researcher

PubMed DOI Crossref

MALDI imaging delineates hippocampal glycosphingolipid changes associated with neurotoxin induced proteopathy following neonatal BMAA exposure.

Karlsson O, Michno W, Ransome Y, Hanrieder J

Biochim Biophys Acta Proteins Proteom 1865 (7) 740-746 [2017-07-00; online 2016-12-09]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Low-algorithmic-complexity entropy-deceiving graphs.

Zenil H, Kiani NA, Tegnér J

Phys Rev E 96 (1-1) 012308 [2017-07-00; online 2017-07-07]

Affiliated researcher

PubMed DOI Crossref

Interferon-α coincides with suppressed levels of pentraxin-3 (PTX3) in systemic lupus erythematosus and regulates leucocyte PTX3 in vitro.

Wirestam L, Enocsson H, Skogh T, ..., Sjöwall C, Wetterö J

Clin. Exp. Immunol. 189 (1) 83-91 [2017-07-00; online 2017-03-31]

Affiliated researcher

PubMed DOI Crossref

High frequency of silver resistance genes in invasive isolates of Enterobacter and Klebsiella species.

Sütterlin S, Dahlö M, Tellgren-Roth C, Schaal W, Melhus Å

J. Hosp. Infect. 96 (3) 256-261 [2017-07-00; online 2017-04-26]

Affiliated researcher

PubMed DOI Crossref

Genomewide analysis of admixture and adaptation in the Africanized honeybee.

Nelson RM, Wallberg A, Simões ZLP, Lawson DJ, Webster MT

Mol. Ecol. 26 (14) 3603-3617 [2017-07-00; online 2017-04-24]

Affiliated researcher

PubMed DOI Crossref

Genetic prevention of hepatitis C virus-induced liver fibrosis by allele-specific downregulation of MERTK.

Cavalli M, Pan G, Nord H, ..., Wallerman O, Wadelius C

Hepatol. Res. 47 (8) 826-830 [2017-07-00; online 2016-09-29]

Affiliated researcher

PubMed DOI Crossref

Functionality testing of stem cell grafts to predict infectious complications after allogeneic hematopoietic stem cell transplantation.

Nilsson J, Granrot I, Mattsson J, ..., Uhlin M, Thunberg S

Vox Sang. 112 (5) 459-468 [2017-07-00; online 2017-05-02]

Affiliated researcher

PubMed DOI Crossref

Evaluating and optimizing the performance of software commonly used for the taxonomic classification of DNA metabarcoding sequence data.

Richardson RT, Bengtsson-Palme J, Johnson RM

Mol Ecol Resour 17 (4) 760-769 [2017-07-00; online 2016-11-21]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.

Young E, Noerenberg D, Mansouri L, ..., Rosenquist R, Damm F

Leukemia 31 (7) 1547-1554 [2017-07-00; online 2016-11-28]

Affiliated researcher

PubMed DOI Crossref

Detection of 6-demethoxyubiquinone in CoQ

Herebian D, Seibt A, Smits SHJ, ..., Mayatepek E, Distelmaier F

Mol. Genet. Metab. 121 (3) 216-223 [2017-07-00; online 2017-05-20]

Affiliated researcher

PubMed DOI Crossref

Constitutive activation of alternative nuclear factor kappa B pathway in canine diffuse large B-cell lymphoma contributes to tumor cell survival and is a target of new adjuvant therapies.

Seelig DM, Ito D, Forster CL, ..., Modiano JF, Linden MA

Leuk. Lymphoma 58 (7) 1702-1710 [2017-07-00; online 2016-12-08]

Affiliated researcher

PubMed DOI Crossref

Close Encounters - Probing Proximal Proteins in Live or Fixed Cells.

Lönn P, Landegren U

Trends Biochem. Sci. 42 (7) 504-515 [2017-07-00; online 2017-05-28]

Affiliated researcher

PubMed DOI Crossref

Autoimmune polyendocrine syndrome type 1 in an Indian cohort: a longitudinal study.

Zaidi G, Bhatia V, Sahoo SK, ..., Agarwal S, Bhatia E

Endocr Connect 6 (5) 289-296 [2017-07-00; online 2017-04-26]

Affiliated researcher

PubMed DOI Crossref

Altered paracellular cation permeability due to a rare CLDN10B variant causes anhidrosis and kidney damage.

Klar J, Piontek J, Milatz S, ..., Günzel D, Dahl N

PLoS Genet 13 (7) e1006897 [2017-07-00; online 2017-07-07]

Affiliated researcher

PubMed DOI Crossref

A longitudinal assessment of miR-122 and GLDH as biomarkers of drug-induced liver injury in the rat.

Thulin P, Hornby RJ, Auli M, ..., Glinghammar B, Schuppe-Koistinen I

Biomarkers 22 (5) 461-469 [2017-07-00; online 2016-12-15]

Affiliated researcher

PubMed DOI Crossref

A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation.

Beloqui A, Brayden DJ, Artursson P, Préat V, des Rieux A

Nat Protoc 12 (7) 1387-1399 [2017-07-00; online 2017-06-15]

Affiliated researcher

PubMed DOI Crossref

A durable and biocompatible ascorbic acid-based covalent coating method of polydimethylsiloxane for dynamic cell culture.

Leivo J, Virjula S, Vanhatupa S, ..., Miettinen S, Kallio P

J R Soc Interface 14 (132) - [2017-07-00; online 2017-07-28]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

A Low-Frequency Inactivating

Manning A, Highland HM, Gasser J, ..., Gloyn AL, Lindgren CM

Diabetes 66 (7) 2019-2032 [2017-07-00; online 2017-03-24]

Affiliated researcher

PubMed DOI Crossref

Regulation of Subunit-Specific Germinal Center B Cell Responses to the HIV-1 Envelope Glycoproteins by Antibody-Mediated Feedback.

Forsell MNE, Kvastad L, Sedimbi SK, Andersson J, Karlsson MCI

Front Immunol 8 (-) 738 [2017-06-30; online 2017-06-30]

Affiliated researcher

PubMed DOI Crossref

Moderate nucleotide diversity in the Atlantic herring is associated with a low mutation rate.

Feng C, Pettersson M, Lamichhaney S, ..., Folkvord A, Andersson L

Elife 6 (-) - [2017-06-30; online 2017-06-30]

Affiliated researcher

PubMed DOI Crossref

The histone H2A isoform Hist2h2ac is a novel regulator of proliferation and epithelial-mesenchymal transition in mammary epithelial and in breast cancer cells.

Monteiro FL, Vitorino R, Wang J, ..., Jerónimo C, Helguero LA

Cancer Lett. 396 (-) 42-52 [2017-06-28; online 2017-03-11]

Affiliated researcher

PubMed DOI Crossref

IL-33 stimulates the release of procoagulant microvesicles from human monocytes and differentially increases tissue factor in human monocyte subsets.

Stojkovic S, Thulin Å, Hell L, ..., Siegbahn A, Åberg M

Thromb. Haemost. 117 (7) 1379-1390 [2017-06-28; online 2017-05-11]

Affiliated researcher

PubMed DOI Crossref

Determination of bending rigidity and tilt modulus of lipid membranes from real-space fluctuation analysis of molecular dynamics simulations.

Doktorova M, Harries D, Khelashvili G

Phys Chem Chem Phys 19 (25) 16806-16818 [2017-06-28; online 2017-06-20]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Advanced Cell Classifier: User-Friendly Machine-Learning-Based Software for Discovering Phenotypes in High-Content Imaging Data.

Piccinini F, Balassa T, Szkalisity A, ..., Smith K, Horvath P

Cell Systems 4 (6) 651-655.e5 [2017-06-28; online 2017-06-21]

Affiliated researcher

PubMed DOI Crossref

Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC.

Strell C, Norberg KJ, Mezheyeuski A, ..., Johansen JS, Östman A

Br. J. Cancer 117 (1) 65-77 [2017-06-27; online 2017-05-18]

Affiliated researcher

PubMed DOI Crossref

Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice.

Martikainen M, Ruotsalainen J, Tuomela J, ..., Heikkilä J, Hinkkanen A

Br. J. Cancer 117 (1) 51-55 [2017-06-27; online 2017-05-30]

Affiliated researcher

PubMed DOI Crossref

GeneSPIDER - gene regulatory network inference benchmarking with controlled network and data properties.

Tjärnberg A, Morgan DC, Studham M, Nordling TEM, Sonnhammer ELL

Mol Biosyst 13 (7) 1304-1312 [2017-06-27; online 2017-05-10]

Affiliated researcher

PubMed DOI Crossref

Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source.

Reddy HKN, Yoon CH, Aquila A, ..., Williams GJ, Xavier PL

Sci Data 4 (-) 170079 [2017-06-27; online 2017-06-27]

Affiliated researcher

PubMed DOI Crossref

A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome.

Diepold A, Sezgin E, Huseyin M, ..., Eggeling C, Armitage JP

Nat Commun 8 (-) 15940 [2017-06-27; online 2017-06-27]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Identification of novel small molecules that inhibit STAT3-dependent transcription and function.

Kolosenko I, Yu Y, Busker S, ..., Page BDG, Grander D

PLoS ONE 12 (6) e0178844 [2017-06-21; online 2017-06-21]

Affiliated researcher

PubMed DOI Crossref

Systems Biology of Metabolism.

Nielsen J

Annu. Rev. Biochem. 86 (-) 245-275 [2017-06-20; online 2017-03-08]

Affiliated researcher

PubMed DOI Crossref

Global Kinetic Mechanism of Microsomal Glutathione Transferase 1 and Insights into Dynamic Enzyme Activation.

Spahiu L, Ålander J, Ottosson-Wadlund A, ..., Armstrong RN, Morgenstern R

Biochemistry 56 (24) 3089-3098 [2017-06-20; online 2017-06-09]

Affiliated researcher

PubMed DOI Crossref

Combining Flow and Mass Cytometry in the Search for Biomarkers in Chronic Graft-versus-Host Disease.

Stikvoort A, Chen Y, Rådestad E, ..., Brodin P, Uhlin M

Front Immunol 8 (-) 717 [2017-06-19; online 2017-06-19]

Affiliated researcher

PubMed DOI Crossref

Synthetic approaches to radiochemical probes for imaging of bacterial infections.

Dutta J, Naicker T, Ebenhan T, ..., Arvidsson PI, Govender T

Eur J Med Chem 133 (-) 287-308 [2017-06-16; online 2017-03-29]

Affiliated researcher

PubMed DOI Crossref

Whole-Genome Sequencing of Drug-Resistant Salmonella enterica Isolates from Dairy Cattle and Humans in New York and Washington States Reveals Source and Geographic Associations.

Carroll LM, Wiedmann M, den Bakker H, ..., Warnick LD, Pereira RV

Applied and environmental microbiology 83 (12) - [2017-06-15; online 2017-05-31]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Insufficient antibody validation challenges oestrogen receptor beta research.

Andersson S, Sundberg M, Pristovsek N, ..., Williams C, Asplund A

Nat Commun 8 (-) 15840 [2017-06-15; online 2017-06-15]

Affiliated researcher

PubMed DOI Crossref

Identification of the adenovirus type 2 C-168 protein.

Gromova A, Zhao H, Konzer A, ..., Pettersson U, Lind SB

Virus Res. 238 (-) 110-113 [2017-06-15; online 2017-06-16]

Affiliated researcher

PubMed DOI Crossref

Free-Energy Calculations of Ionic Hydration Consistent with the Experimental Hydration Free Energy of the Proton.

Zhang H, Jiang Y, Yan H, ..., Tan T, van der Spoel D

J Phys Chem Lett 8 (12) 2705-2712 [2017-06-15; online 2017-06-06]

Affiliated researcher

PubMed DOI Crossref

Stimulated Emission Depletion Microscopy.

Blom H, Widengren J

Chem. Rev. 117 (11) 7377-7427 [2017-06-14; online 2017-03-06]

Affiliated researcher

PubMed DOI Crossref

Results of a collaborative study on DNA identification of aged bone samples.

Vanek D, Budowle B, Dubska-Votrubova J, ..., Vella J, Zander J

Croat Med J 58 (3) 203-213 [2017-06-14; online 2017-06-15]

Affiliated researcher

PubMed DOI Crossref

Genetic loci associated with heart rate variability and their effects on cardiac disease risk.

Nolte IM, Munoz ML, Tragante V, ..., Snieder H, de Geus EJC

Nat Commun 8 (-) 15805 [2017-06-14; online 2017-06-14]

Affiliated researcher

PubMed DOI Crossref

Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost.

Bornelöv S, Seroussi E, Yosefi S, ..., Friedman-Einat M, Andersson L

Genome Biol. 18 (1) 112 [2017-06-14; online 2017-06-14]

Affiliated researcher

PubMed DOI Crossref

Loss of Cardioprotective Effects at the

Saleheen D, Zhao W, Young R, ..., Samani NJ, Reilly MP

Circulation 135 (24) 2336-2353 [2017-06-13; online 2017-05-01]

Affiliated researcher

PubMed DOI Crossref

The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function.

Mehić M, de Sa VK, Hebestreit S, Heldin CH, Heldin P

Oncogenesis 6 (6) e348 [2017-06-12; online 2017-06-12]

Affiliated researcher

PubMed DOI Crossref

Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo).

Maret-Ouda J, Wahlin K, Artama M, ..., Euler-Chelpin MV, Lagergren J

BMJ Open 7 (6) e016505 [2017-06-08; online 2017-06-08]

Affiliated researcher

PubMed DOI Crossref

SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts.

Stattin EL, Henning P, Klar J, ..., Wikström J, Lerner UH

Sci Rep 7 (1) 3012 [2017-06-07; online 2017-06-07]

Affiliated researcher

PubMed DOI Crossref

Multi-level characterization of balanced inhibitory-excitatory cortical neuron network derived from human pluripotent stem cells.

Nadadhur AG, Emperador Melero J, Meijer M, ..., Verhage M, Heine VM

PLoS ONE 12 (6) e0178533 [2017-06-06; online 2017-06-06]

Affiliated researcher

PubMed DOI Crossref

Integrative modeling of gene and genome evolution roots the archaeal tree of life.

Williams TA, Szöllősi GJ, Spang A, ..., Ettema TJG, Embley TM

Proc. Natl. Acad. Sci. U.S.A. 114 (23) E4602-E4611 [2017-06-06; online 2017-05-22]

Affiliated researcher

PubMed DOI Crossref

SAMHD1 protects cancer cells from various nucleoside-based antimetabolites.

Herold N, Rudd SG, Sanjiv K, ..., Henter JI, Schaller T

Cell Cycle 16 (11) 1029-1038 [2017-06-03; online 2017-04-24]

Affiliated researcher

PubMed DOI Crossref

Simultaneous Single-Cell

Krzywkowski T, Ciftci S, Assadian F, Nilsson M, Punga T

J. Virol. 91 (11) - [2017-06-01; online 2017-05-12]

Affiliated researcher

PubMed DOI Crossref

Injury Leads to the Appearance of Cells with Characteristics of Both Microglia and Astrocytes in Mouse and Human Brain.

Wilhelmsson U, Andersson D, de Pablo Y, ..., Pekny M, Pekna M

Cereb. Cortex 27 (6) 3360-3377 [2017-06-01; online 2017-04-12]

Affiliated researcher

PubMed DOI Crossref

Genetic Diversity and the Efficacy of Purifying Selection across Plant and Animal Species.

Chen J, Glémin S, Lascoux M

Mol. Biol. Evol. 34 (6) 1417-1428 [2017-06-01; online 2017-03-24]

Affiliated researcher

PubMed DOI Crossref

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

Aschard H, Tobin MD, Hancock DB, ..., London SJ, Kraft P

Int J Epidemiol 46 (3) 894-904 [2017-06-01; online 2017-01-14]

Affiliated researcher

PubMed DOI Crossref

Diffusion of lipids and GPI-anchored proteins in actin-free plasma membrane vesicles measured by STED-FCS.

Schneider F, Waithe D, Clausen MP, ..., Eggeling C, Sezgin E

Mol. Biol. Cell 28 (11) 1507-1518 [2017-06-01; online 2017-04-12]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Validation of an enzyme-linked immunosorbent assay for the quantification of citrullinated histone H3 as a marker for neutrophil extracellular traps in human plasma.

Thålin C, Daleskog M, Göransson SP, ..., Wallén H, Demers M

Immunol. Res. 65 (3) 706-712 [2017-06-00; online 2017-02-06]

Affiliated researcher

PubMed DOI Crossref

Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib.

Niinivirta M, Enblad G, Edqvist PH, ..., Dragomir A, Ullenhag GJ

J. Cancer Res. Clin. Oncol. 143 (6) 961-970 [2017-06-00; online 2017-03-04]

Affiliated researcher

PubMed DOI Crossref

The mystery of membrane organization: composition, regulation and roles of lipid rafts.

Sezgin E, Levental I, Mayor S, Eggeling C

Nat. Rev. Mol. Cell Biol. 18 (6) 361-374 [2017-06-00; online 2017-03-30]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Structural Variation Detection with Read Pair Information: An Improved Null Hypothesis Reduces Bias.

Sahlin K, Frånberg M, Arvestad L

J. Comput. Biol. 24 (6) 581-589 [2017-06-00; online 2016-09-28]

Affiliated researcher Kristoffer Sahlin SciLifeLab Fellow

PubMed DOI Crossref

Role of interferons in SLE.

Bengtsson AA, Rönnblom L

Best Pract Res Clin Rheumatol 31 (3) 415-428 [2017-06-00; online 2017-11-03]

Affiliated researcher

PubMed DOI Crossref

Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions.

Shungin D, Deng WQ, Varga TV, ..., Paré G, Franks PW

PLoS Genet 13 (6) e1006812 [2017-06-00; online 2017-06-14]

Affiliated researcher

PubMed DOI Crossref

Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking.

Doucet M, Becker KF, Björkman J, ..., Zatloukal K, Dagher G

Biopreserv Biobank 15 (3) 270-276 [2017-06-00; online 2016-12-19]

Affiliated researcher

PubMed DOI Crossref

Multirate method for co-simulation of electrical-chemical systems in multiscale modeling.

Brocke E, Djurfeldt M, Bhalla US, Kotaleski JH, Hanke M

J Comput Neurosci 42 (3) 245-256 [2017-06-00; online 2017-04-07]

Affiliated researcher

PubMed DOI Crossref

Mixing of water masses caused by a drifting iceberg affects bacterial activity, community composition and substrate utilization capability in the Southern Ocean.

Dinasquet J, Richert I, Logares R, ..., Bertilsson S, Riemann L

Environ. Microbiol. 19 (6) 2453-2467 [2017-06-00; online 2017-05-26]

Affiliated researcher

PubMed DOI Crossref

MicroBubble activated acoustic cell sorting.

Faridi MA, Ramachandraiah H, Iranmanesh I, ..., Wiklund M, Russom A

Biomed Microdevices 19 (2) 23 [2017-06-00; online 2017-04-05]

Affiliated researcher

PubMed DOI Crossref

Metastasis detection from whole slide images using local features and random forests.

Valkonen M, Kartasalo K, Liimatainen K, ..., Latonen L, Ruusuvuori P

Cytometry A 91 (6) 555-565 [2017-06-00; online 2017-04-20]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction.

Edvinsson Å, Bränn E, Hellgren C, ..., Cunningham JL, Sundström-Poromaa I

Psychoneuroendocrinology 80 (-) 15-25 [2017-06-00; online 2017-02-28]

Affiliated researcher

PubMed DOI Crossref

Low interleukin-2 concentration favors generation of early memory T cells over effector phenotypes during chimeric antigen receptor T-cell expansion.

Kaartinen T, Luostarinen A, Maliniemi P, ..., Ylä-Herttuala S, Korhonen M

Cytotherapy 19 (6) 689-702 [2017-06-00; online 2017-04-11]

Affiliated researcher

PubMed DOI Crossref

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

Christophersen IE, Rienstra M, Roselli C, ..., Ellinor PT, AFGen Consortium

Nat. Genet. 49 (6) 946-952 [2017-06-00; online 2017-04-17]

Affiliated researcher

PubMed DOI Crossref

LASSIM-A network inference toolbox for genome-wide mechanistic modeling.

Magnusson R, Mariotti GP, Köpsén M, ..., Tjärnberg A, Gustafsson M

PLoS Comput Biol 13 (6) e1005608 [2017-06-00; online 2017-06-22]

Affiliated researcher

PubMed DOI Crossref

Interactions between CXCR4 and CXCL12 promote cell migration and invasion of canine hemangiosarcoma.

Im KS, Graef AJ, Breen M, ..., Modiano JF, Kim JH

Vet Comp Oncol 15 (2) 315-327 [2017-06-00; online 2015-09-03]

Affiliated researcher

PubMed DOI Crossref

Global survey of the immunomodulatory potential of common drugs.

Vladimer GI, Snijder B, Krall N, ..., Jäger U, Superti-Furga G

Nat. Chem. Biol. 13 (6) 681-690 [2017-06-00; online 2017-04-24]

Affiliated researcher

PubMed DOI Crossref

Genome sequencing and population genomic analyses provide insights into the adaptive landscape of silver birch.

Salojärvi J, Smolander OP, Nieminen K, ..., Helariutta Y, Kangasjärvi J

Nat. Genet. 49 (6) 904-912 [2017-06-00; online 2017-05-08]

Affiliated researcher

PubMed DOI Crossref

Gene flow, ancient polymorphism, and ecological adaptation shape the genomic landscape of divergence among Darwin's finches.

Han F, Lamichhaney S, Grant BR, ..., Andersson L, Webster MT

Genome Res. 27 (6) 1004-1015 [2017-06-00; online 2017-04-25]

Affiliated researcher

PubMed DOI Crossref

Fast and general tests of genetic interaction for genome-wide association studies.

Frånberg M, Strawbridge RJ, Hamsten A, ..., Lagergren J, Sennblad B

PLoS Comput Biol 13 (6) e1005556 [2017-06-00; online 2017-06-06]

Affiliated researcher

DOI Crossref

Effects of beaver impoundments on dissolved organic matter quality and biodegradability in boreal riverine systems

Catalán N, Herrero Ortega S, Gröntoft H, ..., Bishop K, Bravo AG

Hydrobiologia 793 (1) 135-148 [2017-06-00; online 2016-05-23]

Affiliated researcher

DOI Crossref

Copernicus, a hybrid dataflow and peer-to-peer scientific computing platform for efficient large-scale ensemble sampling

Pouya I, Pronk S, Lundborg M, Lindahl E

Future Generation Computer Systems 71 (-) 18-31 [2017-06-00; online 2017-06-00]

Affiliated researcher

PubMed DOI Crossref

Comparative proteomics reveals signature metabolisms of exponentially growing and stationary phase marine bacteria.

Muthusamy S, Lundin D, Mamede Branca RM, ..., Lehtiö J, Pinhassi J

Environ. Microbiol. 19 (6) 2301-2319 [2017-06-00; online 2017-04-03]

Affiliated researcher

PubMed DOI Crossref

Building a bio-based industry in the Middle East through harnessing the potential of the Red Sea biodiversity.

Nielsen J, Archer J, Essack M, ..., Gojobori T, Mijakovic I

Appl. Microbiol. Biotechnol. 101 (12) 4837-4851 [2017-06-00; online 2017-05-20]

Affiliated researcher

PubMed DOI Crossref

Association analysis of KIT, MITF, and PAX3 variants with white markings in Spanish horses.

Negro S, Imsland F, Valera M, ..., Solé M, Andersson L

Anim. Genet. 48 (3) 349-352 [2017-06-00; online 2017-01-13]

Affiliated researcher

PubMed DOI Crossref

An automated method measures variability in P-glycoprotein and ABCG2 densities across brain regions and brain matter.

Kannan P, Schain M, Kretzschmar WW, ..., Hall MD, Mulder J

J. Cereb. Blood Flow Metab. 37 (6) 2062-2075 [2017-06-00; online 2016-01-01]

Affiliated researcher

PubMed DOI Crossref

Affinity Proteomics Exploration of Melanoma Identifies Proteins in Serum with Associations to T-Stage and Recurrence.

Byström S, Fredolini C, Edqvist PH, ..., Pontén F, Schwenk JM

Transl Oncol 10 (3) 385-395 [2017-06-00; online 2017-04-20]

Affiliated researcher

PubMed DOI Crossref

A missense variant in ITPR1 provides evidence for autosomal recessive SCA29 with asymptomatic cerebellar hypoplasia in carriers.

Klar J, Ali Z, Farooq M, ..., Baig SM, Dahl N

Eur. J. Hum. Genet. 25 (7) 848-853 [2017-06-00; online 2017-05-10]

Affiliated researcher

PubMed DOI Crossref

High-affinity recognition of the human C-reactive protein independent of phosphocholine.

Yang J, Gustavsson AL, Haraldsson M, ..., Norberg T, Baltzer L

Org. Biomol. Chem. 15 (21) 4644-4654 [2017-05-31; online 2017-05-18]

Affiliated researcher

PubMed DOI Crossref

Expression of CD226 is associated to but not required for NK cell education.

Wagner AK, Kadri N, Snäll J, ..., Kärre K, Chambers BJ

Nat Commun 8 (1) 15627 [2017-05-31; online 2017-05-31]

Affiliated researcher

PubMed DOI Crossref

A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks.

Iannelli F, Galbiati A, Capozzo I, ..., Carninci P, d'Adda di Fagagna F

Nat Commun 8 (-) 15656 [2017-05-31; online 2017-05-31]

Affiliated researcher

PubMed DOI Crossref

The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling.

Su T, Cheng J, Sohmen D, ..., Wilson DN, Beckmann R

Elife 6 (-) - [2017-05-30; online 2017-05-30]

Affiliated researcher

PubMed DOI Crossref

Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2).

Pedersen JM, Khan EK, Bergström CAS, ..., Hoogstraate J, Artursson P

Eur J Pharm Sci 103 (-) 70-76 [2017-05-30; online 2017-03-02]

Affiliated researcher

PubMed DOI Crossref

Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals.

Yu T, Zhou YJ, Wenning L, ..., Nielsen J, David F

Nat Commun 8 (-) 15587 [2017-05-26; online 2017-05-26]

Affiliated researcher

PubMed DOI Crossref

A subcellular map of the human proteome.

Thul PJ, Åkesson L, Wiking M, ..., Uhlén M, Lundberg E

Science (New York, N.Y.) 356 (6340) eaal3321 [2017-05-26; online 2017-05-11]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes.

Väremo L, Henriksen TI, Scheele C, ..., Pedersen BK, Nielsen J

Genome Med 9 (1) 47 [2017-05-25; online 2017-05-25]

Affiliated researcher

PubMed DOI Crossref

Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors.

Llona-Minguez S, Höglund A, Ghassemian A, ..., Scobie M, Helleday T

J. Med. Chem. 60 (10) 4279-4292 [2017-05-25; online 2017-05-16]

Affiliated researcher

PubMed DOI Crossref

RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases.

Battaglia S, Lidschreiber M, Baejen C, ..., Vos SM, Cramer P

Elife 6 (-) - [2017-05-24; online 2017-05-24]

Affiliated researcher

PubMed DOI Crossref

Absolute Quantification of Protein and mRNA Abundances Demonstrate Variability in Gene-Specific Translation Efficiency in Yeast.

Lahtvee PJ, Sánchez BJ, Smialowska A, ..., Gatto F, Nielsen J

Cell Systems 4 (5) 495-504.e5 [2017-05-24; online 2017-03-29]

Affiliated researcher

PubMed DOI Crossref

Targeted sequencing of tonsillar and base of tongue cancer and human papillomavirus positive unknown primary of the head and neck reveals prognostic effects of mutated FGFR3.

Bersani C, Sivars L, Haeggblom L, ..., Ramqvist T, Dalianis T

Oncotarget 8 (21) 35339-35350 [2017-05-23; online 2017-05-20]

Affiliated researcher

PubMed DOI Crossref

Structure of the Sac3 RNA-binding M-region in the Saccharomyces cerevisiae TREX-2 complex.

Gordon JMB, Aibara S, Stewart M

Nucleic Acids Res. 45 (9) 5577-5585 [2017-05-19; online 2017-03-24]

Affiliated researcher

PubMed DOI Crossref

Selective Synthesis of Spirooxindoles by an Intramolecular Heck-Mizoroki Reaction.

Roy T, Brandt P, Wetzel A, ..., Sävmarker J, Larhed M

Org. Lett. 19 (10) 2738-2741 [2017-05-19; online 2017-05-04]

Affiliated researcher

PubMed DOI Crossref

Mass spectrometry based metabolomics for in vitro systems pharmacology: pitfalls, challenges, and computational solutions.

Herman S, Emami Khoonsari P, Aftab O, ..., Kultima K, Gustafsson M

Metabolomics 13 (7) 79 [2017-05-19; online 2017-05-19]

Affiliated researcher

PubMed DOI Crossref

AT

Bernhem K, Krishnan K, Bondar A, ..., Aperia A, Scott L

BMC Cardiovasc Disord 17 (1) 126 [2017-05-17; online 2017-05-17]

Affiliated researcher

PubMed DOI Crossref

ProQ3D: improved model quality assessments using deep learning.

Uziela K, Menéndez Hurtado D, Shu N, Wallner B, Elofsson A

Bioinformatics 33 (10) 1578-1580 [2017-05-15; online 2017-01-06]

Affiliated researcher

PubMed DOI Crossref

Multifractal and mechanical analysis of amorphous solid dispersions.

Adler C, Teleki A, Kuentz M

Int J Pharm 523 (1) 91-101 [2017-05-15; online 2017-03-09]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

GWAR: robust analysis and meta-analysis of genome-wide association studies.

Dimou NL, Tsirigos KD, Elofsson A, Bagos PG

Bioinformatics 33 (10) 1521-1527 [2017-05-15; online 2017-01-22]

Affiliated researcher

PubMed DOI Crossref

Spectral imaging toolbox: segmentation, hyperstack reconstruction, and batch processing of spectral images for the determination of cell and model membrane lipid order.

Aron M, Browning R, Carugo D, ..., Eggeling C, Stride E

BMC Bioinformatics 18 (1) 254 [2017-05-12; online 2017-05-12]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks.

Yan WX, Mirzazadeh R, Garnerone S, ..., Bienko M, Crosetto N

Nat Commun 8 (1) 15058 [2017-05-12; online 2017-05-12]

Affiliated researcher Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Whole blood gene expression in adolescent chronic fatigue syndrome: an exploratory cross-sectional study suggesting altered B cell differentiation and survival.

Nguyen CB, Alsøe L, Lindvall JM, ..., Nilsen H, Wyller VB

J Transl Med 15 (1) 102 [2017-05-11; online 2017-05-11]

Affiliated researcher

PubMed DOI Crossref

Piecewise Structural Equation Model (SEM) Disentangles the Environmental Conditions Favoring Diatom Diazotroph Associations (DDAs) in the Western Tropical North Atlantic (WTNA).

Stenegren M, Berg C, Padilla CC, ..., Yager PL, Foster RA

Front Microbiol 8 (-) 810 [2017-05-09; online 2017-05-09]

Affiliated researcher

PubMed DOI Crossref

Phase Partitioning of GM1 and Its Bodipy-Labeled Analog Determine Their Different Binding to Cholera Toxin.

Rissanen S, Grzybek M, Orłowski A, ..., Sezgin E, Vattulainen I

Front. Physiol. 8 (-) 252 [2017-05-09; online 2017-05-09]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Spatially resolved transcriptome profiling in model plant species.

Giacomello S, Salmén F, Terebieniec BK, ..., Street NR, Lundeberg J

Nat Plants 3 (-) 17061 [2017-05-08; online 2017-05-08]

Affiliated researcher Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis.

Abadpour S, Göpel SO, Schive SW, ..., Foss A, Scholz H

Sci Rep 7 (1) 1575 [2017-05-08; online 2017-05-08]

Affiliated researcher

PubMed DOI Crossref

Expression proteomics study to determine metallodrug targets and optimal drug combinations.

Lee RFS, Chernobrovkin A, Rutishauser D, ..., Zubarev RA, Dyson PJ

Sci Rep 7 (1) 1590 [2017-05-08; online 2017-05-08]

Affiliated researcher

PubMed DOI Crossref

Sensitive and inexpensive digital DNA analysis by microfluidic enrichment of rolling circle amplified single-molecules.

Kühnemund M, Hernández-Neuta I, Sharif MI, ..., Gijs MAM, Nilsson M

Nucleic Acids Res. 45 (8) e59 [2017-05-05; online 2017-01-13]

Affiliated researcher

PubMed DOI Crossref

Screening and Validation of Novel Biomarkers in Osteoarticular Pathologies by Comprehensive Combination of Protein Array Technologies.

Sierra-Sánchez Á, Garrido-Martín D, Lourido L, ..., Blanco F, Fuentes M

J. Proteome Res. 16 (5) 1890-1899 [2017-05-05; online 2017-04-17]

Affiliated researcher

PubMed DOI Crossref

FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome.

Wucher V, Legeai F, Hédan B, ..., Hitte C, Derrien T

Nucleic Acids Res. 45 (8) e57 [2017-05-05; online 2017-01-06]

Affiliated researcher

PubMed DOI Crossref

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.

Shi W, Vu T, Boucher D, ..., Lane SW, Khanna KK

Blood 129 (18) 2479-2492 [2017-05-04; online 2017-03-07]

Affiliated researcher

PubMed DOI Crossref

Single-cell RNA-sequencing: The future of genome biology is now.

Picelli S

RNA Biol 14 (5) 637-650 [2017-05-04; online 2016-07-21]

Affiliated researcher

PubMed DOI Crossref

Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation.

Padhan N, Yan J, Boge A, ..., Claesson-Welsh L, Landegren U

Sci Rep 7 (1) 1490 [2017-05-04; online 2017-05-04]

Affiliated researcher

PubMed DOI Crossref

EndoC-βH1 cells display increased sensitivity to sodium palmitate when cultured in DMEM/F12 medium.

Krizhanovskii C, Kristinsson H, Elksnis A, ..., Scharfmann R, Welsh N

Islets 9 (3) e1296995 [2017-05-04; online 2017-02-28]

Affiliated researcher

PubMed DOI Crossref

Functional screening of aldehyde decarbonylases for long-chain alkane production by Saccharomyces cerevisiae.

Kang MK, Zhou YJ, Buijs NA, Nielsen J

Microb Cell Fact 16 (1) 74 [2017-05-02; online 2017-05-02]

Affiliated researcher

PubMed DOI Crossref

Colonization and Succession within the Human Gut Microbiome by Archaea, Bacteria, and Microeukaryotes during the First Year of Life.

Wampach L, Heintz-Buschart A, Hogan A, ..., de Beaufort C, Wilmes P

Front Microbiol 8 (-) 738 [2017-05-02; online 2017-05-02]

Affiliated researcher DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Temporal Genomic Phylogeny Reconstruction Indicates a Geospatial Transmission Path of Salmonella Cerro in the United States and a Clade-Specific Loss of Hydrogen Sulfide Production.

Kovac J, Cummings KJ, Rodriguez-Rivera LD, ..., Thachil A, Wiedmann M

Front Microbiol 8 (-) 737 [2017-05-01; online 2017-05-01]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.

Wild PS, Felix JF, Schillert A, ..., Vasan RS, Dörr M

J. Clin. Invest. 127 (5) 1798-1812 [2017-05-01; online 2017-04-10]

Affiliated researcher

PubMed DOI Crossref

Experimental strategies for imaging bioparticles with femtosecond hard X-ray pulses.

Daurer BJ, Okamoto K, Bielecki J, ..., Hajdu J, Larsson DSD

IUCrJ 4 (Pt 3) 251-262 [2017-05-01; online 2017-04-07]

Affiliated researcher

PubMed DOI Crossref

[ 11C]5-hydroxy-tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes.

Carlbom L, Espes D, Lubberink M, ..., Korsgren O, Eriksson O

Diabetes 66 (5) 1286-1292 [2017-05-00; online 2017-02-28]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Two extended haplotype blocks are associated with adaptation to high altitude habitats in East African honey bees.

Wallberg A, Schöning C, Webster MT, Hasselmann M

PLoS Genet 13 (5) e1006792 [2017-05-00; online 2017-05-25]

Affiliated researcher

PubMed DOI Crossref

Transcriptomics and methylomics of CD4-positive T cells in arsenic-exposed women.

Engström K, Wojdacz TK, Marabita F, ..., Vahter M, Broberg K

Arch. Toxicol. 91 (5) 2067-2078 [2017-05-00; online 2016-11-12]

Affiliated researcher

PubMed DOI Crossref

Time to onset of bisphosphonate-related osteonecrosis of the jaws: a multicentre retrospective cohort study.

Fung P, Bedogni G, Bedogni A, ..., GENVABO Consortium , Fedele S

Oral Dis 23 (4) 477-483 [2017-05-00; online 2017-03-06]

Affiliated researcher

PubMed DOI Crossref

The origin of novel features by changes in developmental mechanisms: ontogeny and three-dimensional microanatomy of polyodontode scales of two early osteichthyans.

Qu Q, Sanchez S, Zhu M, Blom H, Ahlberg PE

Biol Rev Camb Philos Soc 92 (2) 1189-1212 [2017-05-00; online 2016-05-19]

Affiliated researcher

PubMed DOI Crossref

Ten simple rules for surviving an interdisciplinary PhD.

Demharter S, Pearce N, Beattie K, ..., Deane CM, Knapp B

PLoS Comput Biol 13 (5) e1005512 [2017-05-00; online 2017-05-25]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

Stress sensitivity of a fission yeast strain lacking histidine kinases is rescued by the ectopic expression of Chk1 from Candida albicans.

Maksimov V, Wäneskog M, Rodriguez A, Bjerling P

Curr. Genet. 63 (2) 343-357 [2017-05-00; online 2016-09-09]

Affiliated researcher

PubMed DOI Crossref

Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR.

Borgatti A, Koopmeiners JS, Sarver AL, ..., Modiano JF, Vallera DA

Mol. Cancer Ther. 16 (5) 956-965 [2017-05-00; online 2017-02-13]

Affiliated researcher

PubMed DOI Crossref

Recent Advances in Human Genetics and Epigenetics of Adiposity: Pathway to Precision Medicine?

Fall T, Mendelson M, Speliotes EK

Gastroenterology 152 (7) 1695-1706 [2017-05-00; online 2017-02-15]

Affiliated researcher

PubMed DOI Crossref

Partial-occupancy binders identified by the Pan-Dataset Density Analysis method offer new chemical opportunities and reveal cryptic binding sites.

Pearce NM, Bradley AR, Krojer T, ..., Deane CM, von Delft F

Struct Dyn 4 (3) 032104 [2017-05-00; online 2017-02-28]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

Monitoring therapy responses at the leukemic subclone level by ultra-deep amplicon resequencing in acute myeloid leukemia.

Ojamies PN, Kontro M, Edgren H, ..., Wolf M, Kallioniemi O

Leukemia 31 (5) 1048-1058 [2017-05-00; online 2016-10-31]

Affiliated researcher

PubMed DOI Crossref

Loss of chromosome Y (LOY) in blood cells is associated with increased risk for disease and mortality in aging men.

Forsberg LA

Hum. Genet. 136 (5) 657-663 [2017-05-00; online 2017-04-19]

Affiliated researcher

PubMed DOI Crossref

Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study.

Bränn E, Papadopoulos F, Fransson E, ..., Sundström-Poromaa I, Skalkidou A

Psychoneuroendocrinology 79 (-) 146-159 [2017-05-00; online 2017-02-28]

Affiliated researcher

PubMed DOI Crossref

Further evidence for specific IFIH1 mutation as a cause of Singleton-Merten syndrome with phenotypic heterogeneity.

Pettersson M, Bergendal B, Norderyd J, ..., Nordgren A, Lindstrand A

Am. J. Med. Genet. A 173 (5) 1396-1399 [2017-05-00; online 2017-03-20]

Affiliated researcher

PubMed DOI Crossref

Evolutionary forces affecting synonymous variations in plant genomes.

Clément Y, Sarah G, Holtz Y, ..., David J, Glémin S

PLoS Genet 13 (5) e1006799 [2017-05-00; online 2017-05-22]

Affiliated researcher

PubMed DOI Crossref

Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML.

Malani D, Murumägi A, Yadav B, ..., Aittokallio T, Kallioniemi O

Leukemia 31 (5) 1187-1195 [2017-05-00; online 2016-11-11]

Affiliated researcher

PubMed DOI Crossref

Engineering central metabolism - a grand challenge for plant biologists.

Sweetlove LJ, Nielsen J, Fernie AR

Plant J. 90 (4) 749-763 [2017-05-00; online 2017-03-11]

Affiliated researcher

PubMed DOI Crossref

Development of cyclic shedding teeth from semi-shedding teeth: the inner dental arcade of the stem osteichthyan

Chen D, Blom H, Sanchez S, ..., Märss T, Ahlberg PE

R Soc Open Sci 4 (5) 161084 [2017-05-00; online 2017-05-17]

Affiliated researcher

PubMed DOI Crossref

Covariation of Peptide Abundances Accurately Reflects Protein Concentration Differences.

Zhang B, Pirmoradian M, Zubarev R, Käll L

Mol. Cell Proteomics 16 (5) 936-948 [2017-05-00; online 2017-03-16]

Affiliated researcher

PubMed DOI Crossref

Combination of short-read, long-read, and optical mapping assemblies reveals large-scale tandem repeat arrays with population genetic implications.

Weissensteiner MH, Pang AWC, Bunikis I, ..., Suh A, Wolf JBW

Genome Res. 27 (5) 697-708 [2017-05-00; online 2017-03-30]

Affiliated researcher

PubMed DOI Crossref

Biobased production of alkanes and alkenes through metabolic engineering of microorganisms.

Kang MK, Nielsen J

J. Ind. Microbiol. Biotechnol. 44 (4-5) 613-622 [2017-05-00; online 2016-08-26]

Affiliated researcher

PubMed DOI Crossref

An intra-droplet particle switch for droplet microfluidics using bulk acoustic waves.

Fornell A, Ohlin M, Garofalo F, Nilsson J, Tenje M

Biomicrofluidics 11 (3) 031101 [2017-05-00; online 2017-05-26]

Affiliated researcher

PubMed DOI Crossref

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.

Gorski M, van der Most PJ, Teumer A, ..., Böger CA, Fuchsberger C

Sci Rep 7 (-) 45040 [2017-04-28; online 2017-04-28]

Affiliated researcher

PubMed DOI Crossref

Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress.

Chroma K, Mistrik M, Moudry P, ..., Kramara J, Bartek J

Oncogene 36 (17) 2405-2422 [2017-04-27; online 2016-11-14]

Affiliated researcher

PubMed DOI Crossref

High-avidity IgA protects the intestine by enchaining growing bacteria.

Moor K, Diard M, Sellin ME, ..., Hardt WD, Slack E

Nature 544 (7651) 498-502 [2017-04-27; online 2017-04-12]

Affiliated researcher Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Combined lipidomic and proteomic analysis of isolated human islets exposed to palmitate reveals time-dependent changes in insulin secretion and lipid metabolism.

Roomp K, Kristinsson H, Schvartz D, ..., Sanchez JC, Bergsten P

PLoS ONE 12 (4) e0176391 [2017-04-27; online 2017-04-27]

Affiliated researcher

PubMed DOI Crossref

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

Justice AE, Winkler TW, Feitosa MF, ..., North KE, Cupples LA

Nat Commun 8 (-) 14977 [2017-04-26; online 2017-04-26]

Affiliated researcher

PubMed DOI Crossref

Recombinant TgHSP70 Immunization Protects against Toxoplasma gondii Brain Cyst Formation by Enhancing Inducible Nitric Oxide Expression

Czarnewski P, Araújo ECB, Oliveira MC, Mineo TWP, Silva NM

Front. Cell. Infect. Microbiol. 7 (-) - [2017-04-25; online 2017-04-25]

Affiliated researcher

PubMed DOI Crossref

Parallel adaptive evolution of geographically distant herring populations on both sides of the North Atlantic Ocean.

Lamichhaney S, Fuentes-Pardo AP, Rafati N, ..., Ruzzante DE, Andersson L

Proc. Natl. Acad. Sci. U.S.A. 114 (17) E3452-E3461 [2017-04-25; online 2017-04-07]

Affiliated researcher

PubMed DOI Crossref

A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.

Pearce NM, Krojer T, Bradley AR, ..., Deane CM, von Delft F

Nat Commun 8 (-) 15123 [2017-04-24; online 2017-04-24]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

A large-scale benchmark of gene prioritization methods.

Guala D, Sonnhammer ELL

Sci Rep 7 (-) 46598 [2017-04-21; online 2017-04-21]

Affiliated researcher

PubMed DOI Crossref

Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model.

Tegelberg S, Tomašić N, Kallijärvi J, ..., Eklund EA, Fellman V

Orphanet J Rare Dis 12 (1) 73 [2017-04-20; online 2017-04-20]

Affiliated researcher

PubMed DOI Crossref

Pharmacological targeting of peptidylarginine deiminase 4 prevents cancer-associated kidney injury in mice.

Cedervall J, Dragomir A, Saupe F, ..., Larsson A, Olsson AK

Oncoimmunology 6 (8) e1320009 [2017-04-20; online 2017-04-20]

Affiliated researcher

PubMed DOI Crossref

Persistent Effects of Developmental Exposure to 17α-Ethinylestradiol on the Zebrafish (

Porseryd T, Volkova K, Reyhanian Caspillo N, ..., Dinnetz P, Porsh Hällström I

Front Behav Neurosci 11 (-) 69 [2017-04-20; online 2017-04-20]

Affiliated researcher

PubMed DOI Crossref

Formal Definitions of Unbounded Evolution and Innovation Reveal Universal Mechanisms for Open-Ended Evolution in Dynamical Systems.

Adams A, Zenil H, Davies PCW, Walker SI

Sci Rep 7 (1) 997 [2017-04-20; online 2017-04-20]

Affiliated researcher

PubMed DOI Crossref

Does Proton Conduction in the Voltage-Gated H+ Channel hHv1 Involve Grotthuss-Like Hopping via Acidic Residues?

van Keulen SC, Gianti E, Carnevale V, ..., Rothlisberger U, Delemotte L

J Phys Chem B 121 (15) 3340-3351 [2017-04-20; online 2016-11-18]

Affiliated researcher Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

AS3MT-mediated tolerance to arsenic evolved by multiple independent horizontal gene transfers from bacteria to eukaryotes.

Palmgren M, Engström K, Hallström BM, ..., Vahter M, Broberg K

PLoS ONE 12 (4) e0175422 [2017-04-20; online 2017-04-20]

Affiliated researcher

PubMed DOI Crossref

Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.

Weber H, Valbuena JR, Barbhuiya MA, ..., Leal-Rojas P, Roa JC

Oncotarget 8 (16) 26169-26184 [2017-04-18; online 2017-04-17]

Affiliated researcher

PubMed DOI Crossref

Histology-Compatible MALDI Mass Spectrometry Based Imaging of Neuronal Lipids for Subsequent Immunofluorescent Staining.

Kaya I, Michno W, Brinet D, ..., Zetterberg H, Hanrieder J

Anal. Chem. 89 (8) 4685-4694 [2017-04-18; online 2017-04-06]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage.

Kaucka M, Zikmund T, Tesarova M, ..., Fried K, Adameyko I

Elife 6 (-) - [2017-04-17; online 2017-04-17]

Affiliated researcher

PubMed DOI Crossref

Possible Interaction Between Cigarette Smoking and HLA-DRB1 Variation in the Risk of Follicular Lymphoma.

Baecklund F, Foo JN, Askling J, ..., Padyukov L, Smedby KE

Am. J. Epidemiol. 185 (8) 681-687 [2017-04-15; online 2017-04-04]

Affiliated researcher

PubMed DOI Crossref

Improved orthology inference with Hieranoid 2.

Kaduk M, Sonnhammer E

Bioinformatics 33 (8) 1154-1159 [2017-04-15; online 2017-01-18]

Affiliated researcher

PubMed DOI Crossref

Adaptation to infectious disease exposure in indigenous Southern African populations.

Owers KA, Sjödin P, Schlebusch CM, ..., Soodyall H, Jakobsson M

Proc. Biol. Sci. 284 (1852) - [2017-04-12; online 2017-04-07]

Affiliated researcher

PubMed DOI Crossref

The transcription factor MAFK induces EMT and malignant progression of triple-negative breast cancer cells through its target GPNMB.

Okita Y, Kimura M, Xie R, ..., Heldin CH, Kato M

Sci Signal 10 (474) - [2017-04-11; online 2017-04-11]

Affiliated researcher

PubMed DOI Crossref

Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression.

Roy A, Attarha S, Weishaupt H, ..., Pontén F, Tchougounova E

Oncotarget 8 (15) 24815-24827 [2017-04-11; online 2017-04-28]

Affiliated researcher

PubMed DOI Crossref

Direct evidence for a polygenic etiology in familial multiple myeloma.

Halvarsson BM, Wihlborg AK, Ali M, ..., Hansson M, Nilsson B

Blood Adv 1 (10) 619-623 [2017-04-11; online 2017-04-07]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

SPlinted Ligation Adapter Tagging (SPLAT), a novel library preparation method for whole genome bisulphite sequencing.

Raine A, Manlig E, Wahlberg P, Syvänen AC, Nordlund J

Nucleic Acids Res. 45 (6) e36 [2017-04-07; online 2016-12-03]

Affiliated researcher

PubMed DOI Crossref

Regio- and Stereoselective Synthesis of Functionalized Cyclopentene Derivatives via Mizoroki-Heck Reactions.

Wetzel A, Bergman J, Brandt P, Larhed M, Brånalt J

Org. Lett. 19 (7) 1602-1605 [2017-04-07; online 2017-03-14]

Affiliated researcher

PubMed DOI Crossref

Genome-wide identification of physically clustered genes suggests chromatin-level co-regulation in male reproductive development in Arabidopsis thaliana.

Reimegård J, Kundu S, Pendle A, ..., Sundström JF, Emanuelsson O

Nucleic Acids Res. 45 (6) 3253-3265 [2017-04-07; online 2017-02-09]

Affiliated researcher

PubMed DOI Crossref

A Fluorophore Fusion Construct of Human Profilin I with Non-Compromised Poly(L-Proline) Binding Capacity Suitable for Imaging.

Nejedla M, Li Z, Masser AE, ..., Friedländer MR, Karlsson R

J. Mol. Biol. 429 (7) 964-976 [2017-04-07; online 2017-01-08]

Affiliated researcher Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Quantitative humoral profiling of the HIV-1 proteome in elite controllers and patients with very long-term efficient antiretroviral therapy.

Zhang W, Morshed MM, Noyan K, ..., Sönnerborg A, Neogi U

Sci Rep 7 (1) 666 [2017-04-06; online 2017-04-06]

Affiliated researcher

PubMed DOI Crossref

Interplay between periodic stimulation and GABAergic inhibition in striatal network oscillations.

Belić JJ, Kumar A, Hellgren Kotaleski J

PLoS ONE 12 (4) e0175135 [2017-04-06; online 2017-04-06]

Affiliated researcher

PubMed DOI Crossref

Genome-wide Analysis of RNA Polymerase II Termination at Protein-Coding Genes.

Baejen C, Andreani J, Torkler P, ..., Söding J, Cramer P

Mol. Cell 66 (1) 38-49.e6 [2017-04-06; online 2017-03-16]

Affiliated researcher

PubMed DOI Crossref

Quantum dots modulate intracellular Ca

Yin H, Fontana JM, Solandt J, ..., Brismar H, Fu Y

Int J Nanomedicine 12 (-) 2781-2792 [2017-04-05; online 2017-04-05]

Affiliated researcher

PubMed DOI Crossref

Laurdan and Di-4-ANEPPDHQ probe different properties of the membrane.

Amaro M, Reina F, Hof M, Eggeling C, Sezgin E

J. Phys. D: Appl. Phys. 50 (13) 134004 [2017-04-05; online 2017-03-07]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

dUTPase inhibition augments replication defects of 5-Fluorouracil.

Hagenkort A, Paulin CBJ, Desroses M, ..., Scobie M, Helleday T

Oncotarget 8 (14) 23713-23726 [2017-04-04; online 2017-04-21]

Affiliated researcher

PubMed DOI Crossref

Optimizing Analytical Depth and Cost Efficiency of IEF-LC/MS Proteomics.

Kifer I, Branca RM, Ben-Dor A, ..., Lehtio J, Yakhini Z

IEEE/ACM Trans Comput Biol Bioinform 14 (2) 272-281 [2017-04-04; online 2017-04-04]

Affiliated researcher

PubMed DOI Crossref

Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia.

Löf L, Arngården L, Olsson-Strömberg U, ..., Landegren U, Kamali-Moghaddam M

Sci Rep 7 (1) 623 [2017-04-04; online 2017-04-04]

Affiliated researcher

PubMed DOI Crossref

Sulfonimidamides in Medicinal and Agricultural Chemistry.

Chinthakindi PK, Naicker T, Thota N, ..., Kruger HG, Arvidsson PI

Angew. Chem. Int. Ed. Engl. 56 (15) 4100-4109 [2017-04-03; online 2017-02-23]

Affiliated researcher

PubMed DOI Crossref

Global analysis of biosynthetic gene clusters reveals vast potential of secondary metabolite production in Penicillium species.

Nielsen JC, Grijseels S, Prigent S, ..., Workman M, Nielsen J

Nat. Microbiol 2 (-) 17044 [2017-04-03; online 2017-04-03]

Affiliated researcher

PubMed DOI Crossref

Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer.

Mathot L, Kundu S, Ljungström V, ..., Nilsson M, Sjöblom T

Cancer Res. 77 (7) 1730-1740 [2017-04-01; online 2017-01-20]

Affiliated researcher

PubMed DOI Crossref

Menopausal hormone therapy and the risk of esophageal and gastric cancer.

Brusselaers N, Maret-Ouda J, Konings P, El-Serag HB, Lagergren J

Int. J. Cancer 140 (7) 1693-1699 [2017-04-01; online 2017-01-06]

Affiliated researcher

PubMed DOI Crossref

Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses.

Niklasson M, Maddalo G, Sramkova Z, ..., Enger PØ, Andäng M

Cancer Res. 77 (7) 1741-1752 [2017-04-01; online 2017-01-13]

Affiliated researcher

PubMed DOI Crossref

Interactions of Freshwater Cyanobacteria with Bacterial Antagonists.

Osman OA, Beier S, Grabherr M, Bertilsson S

Appl. Environ. Microbiol. 83 (7) - [2017-04-01; online 2017-03-17]

Affiliated researcher

PubMed DOI Crossref

Discrimination of pancreatic cancer and pancreatitis by LC-MS metabolomics.

Lindahl A, Heuchel R, Forshed J, ..., Löhr M, Nordström A

Metabolomics 13 (5) 61 [2017-04-01; online 2017-04-01]

Affiliated researcher

PubMed DOI Crossref

The evolution of Sex-linked barring alleles in chickens involves both regulatory and coding changes in CDKN2A.

Schwochow Thalmann D, Ring H, Sundström E, ..., Tixier-Boichard M, Andersson L

PLoS Genet 13 (4) e1006665 [2017-04-00; online 2017-04-07]

Affiliated researcher

PubMed DOI Crossref

Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts.

Kang W, Bang-Berthelsen CH, Holm A, ..., Estivill X, Friedländer MR

RNA 23 (4) 433-445 [2017-04-00; online 2017-01-06]

Affiliated researcher Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Sequence dependency of canonical base pair opening in the DNA double helix.

Lindahl V, Villa A, Hess B

PLoS Comput Biol 13 (4) e1005463 [2017-04-00; online 2017-04-03]

Affiliated researcher

DOI Crossref

Sensitive magnetic biodetection using magnetic multi-core nanoparticles and RCA coils

Ahrentorp F, Blomgren J, Jonasson C, ..., Strømme M, Johansson C

Journal of Magnetism and Magnetic Materials 427 (-) 14-18 [2017-04-00; online 2017-04-00]

Affiliated researcher

PubMed DOI Crossref

Redesign of water networks for efficient biocatalysis.

Fink MJ, Syrén PO

Curr Opin Chem Biol 37 (-) 107-114 [2017-04-00; online 2017-03-05]

Affiliated researcher

PubMed DOI Crossref

Prediction and Prevention of Parasitic Diseases Using a Landscape Genomics Framework.

Schwabl P, Llewellyn MS, Landguth EL, ..., Ocaña S, Grijalva MJ

Trends Parasitol. 33 (4) 264-275 [2017-04-00; online 2016-11-16]

Affiliated researcher

PubMed DOI Crossref

Predicting Severity of Disease-Causing Variants.

Niroula A, Vihinen M

Hum. Mutat. 38 (4) 357-364 [2017-04-00; online 2017-01-24]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.

Folkersen L, Fauman E, Sabater-Lleal M, ..., Hamsten A, Mälarstig A

PLoS Genet 13 (4) e1006706 [2017-04-00; online 2017-04-03]

Affiliated researcher

PubMed DOI Crossref

Human behavioral complexity peaks at age 25.

Gauvrit N, Zenil H, Soler-Toscano F, Delahaye JP, Brugger P

PLoS Comput Biol 13 (4) e1005408 [2017-04-00; online 2017-04-13]

Affiliated researcher

PubMed DOI Crossref

Higher Nevus Count Exhibits a Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma.

Roos L, Sandling JK, Bell CG, ..., Bataille V, Bell JT

J. Invest. Dermatol. 137 (4) 910-920 [2017-04-00; online 2016-12-18]

Affiliated researcher

PubMed DOI Crossref

Genomic analysis reveals the presence of a class D beta-lactamase with broad substrate specificity in animal bite associated Capnocytophaga species.

Zangenah S, Andersson AF, Özenci V, Bergman P

Eur. J. Clin. Microbiol. Infect. Dis. 36 (4) 657-662 [2017-04-00; online 2016-12-01]

Affiliated researcher

PubMed DOI Crossref

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

Graff M, Scott RA, Justice AE, ..., Loos RJF, Kilpeläinen TO

PLoS Genet 13 (4) e1006528 [2017-04-00; online 2017-04-27]

Affiliated researcher

PubMed DOI Crossref

Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs.

Petros Z, Lee MT, Takahashi A, ..., Kubo M, Aklillu E

OMICS 21 (4) 207-216 [2017-04-00; online 2017-04-08]

Affiliated researcher

PubMed DOI Crossref

Genetic variants in the promoter region of the calcium-sensing receptor gene are associated with its down-regulation in neuroblastic tumors.

Masvidal L, Iniesta R, García M, ..., Mora J, de Torres C

Mol. Carcinog. 56 (4) 1281-1289 [2017-04-00; online 2016-11-24]

Affiliated researcher

PubMed DOI Crossref

Gene expression profiles in preterm infants on continuous long‑term oxygen therapy suggest reduced oxidative stress‑dependent signaling during hypoxia.

Kalikstad B, Kultima HG, Andersstuen TK, Klungland A, Isaksson A

Mol Med Rep 15 (4) 1513-1526 [2017-04-00; online 2017-02-08]

Affiliated researcher

PubMed DOI Crossref

Frequent low-level mutations of protein kinase D2 in angiolipoma.

Hofvander J, Arbajian E, Stenkula KG, ..., Hornick JL, Mertens F

J. Pathol. 241 (5) 578-582 [2017-04-00; online 2017-02-27]

Affiliated researcher

PubMed DOI Crossref

FZD

Hot B, Valnohova J, Arthofer E, ..., Mulder J, Schulte G

Cell. Signal. 32 (-) 93-103 [2017-04-00; online 2017-01-24]

Affiliated researcher

PubMed DOI Crossref

Expanding the product portfolio of fungal type I fatty acid synthases.

Zhu Z, Zhou YJ, Krivoruchko A, ..., Zhao ZK, Nielsen J

Nat. Chem. Biol. 13 (4) 360-362 [2017-04-00; online 2017-02-20]

Affiliated researcher

PubMed DOI Crossref

Epigenome-wide DNA methylation study of IgE concentration in relation to self-reported allergies.

Ek WE, Ahsan M, Rask-Andersen M, ..., Gyllensten U, Johansson Å

Epigenomics 9 (4) 407-418 [2017-04-00; online 2017-03-21]

Affiliated researcher

DOI Crossref

Automated Line-Based Sequential Sampling and Modeling Algorithm for EMC Near-Field Scanning

Singh P, Claeys T, Vandenbosch GAE, Pissoort D

IEEE Trans. Electromagn. Compat. 59 (2) 704-709 [2017-04-00; online 2017-04-00]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.

Nicoletti P, Aithal GP, Bjornsson ES, ..., Daly AK, International Drug-Induced Liver Injury Consortium, Drug-Induced Liver Injury Network Investigators, and International Serious Adverse Events Consortium

Gastroenterology 152 (5) 1078-1089 [2017-04-00; online 2016-12-30]

Affiliated researcher

DOI Crossref

Antibiotic resistance in the food supply chain: where can sequencing and metagenomics aid risk assessment?

Bengtsson-Palme J

Current Opinion in Food Science 14 (-) 66-71 [2017-04-00; online 2017-04-00]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Analysis of FOXP3

Schmidt A, Rieger CC, Venigalla RK, ..., Krammer PH, Kuhn A

Immunol. Res. 65 (2) 551-563 [2017-04-00; online 2017-02-23]

Affiliated researcher

PubMed DOI Crossref

Alterations in Multiple Lifestyle Factors in Subjects with the Metabolic Syndrome Independently of Obesity.

Roos V, Elmståhl S, Ingelsson E, ..., Ärnlöv J, Lind L

Metab Syndr Relat Disord 15 (3) 118-123 [2017-04-00; online 2017-02-16]

Affiliated researcher

PubMed DOI Crossref

AUP1 (Ancient Ubiquitous Protein 1): A Molecular Link Between Hepatic Lipid Mobilization and VLDL Secretion.

Mardinoglu A, Borén J

Arterioscler. Thromb. Vasc. Biol. 37 (4) 609-610 [2017-04-00; online 2017-03-24]

Adil Mardinoglu SciLifeLab Fellow

DOI Crossref

A sequential sampling strategy for adaptive classification of computationally expensive data

Singh P, Herten Jvd, Deschrijver D, Couckuyt I, Dhaene T

Struct Multidisc Optim 55 (4) 1425-1438 [2017-04-00; online 2016-09-22]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

A Magnetic Nanobead-Based Read-Out Procedure for Rapid Detection of DNA Molecules.

Gómez de la Torre TZ, Herthnek D, Strømme M

j nanosci nanotechnol 17 (4) 2861-2864 [2017-04-00; online 2018-04-19]

Affiliated researcher

PubMed DOI Crossref

A Large Inversion Involving GNAS Exon A/B and All Exons Encoding Gsα Is Associated With Autosomal Dominant Pseudohypoparathyroidism Type Ib (PHP1B).

Grigelioniene G, Nevalainen PI, Reyes M, ..., Mäkitie O, Jüppner H

J. Bone Miner. Res. 32 (4) 776-783 [2017-04-00; online 2017-02-24]

Affiliated researcher

PubMed DOI Crossref

Electroformation of Giant Unilamellar Vesicles on Stainless Steel Electrodes.

Pereno V, Carugo D, Bau L, ..., Eggeling C, Stride E

ACS Omega 2 (3) 994-1002 [2017-03-31; online 2017-03-16]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Improvement of identification methods for honeybee specific Lactic Acid Bacteria; future approaches.

Lamei S, Hu YO, Olofsson TC, ..., Forsgren E, Vásquez A

PLoS ONE 12 (3) e0174614 [2017-03-27; online 2017-03-27]

Affiliated researcher

PubMed DOI Crossref

Potential for hydrogen-oxidizing chemolithoautotrophic and diazotrophic populations to initiate biofilm formation in oligotrophic, deep terrestrial subsurface waters.

Wu X, Pedersen K, Edlund J, ..., Bertilsson S, Dopson M

Microbiome 5 (1) 37 [2017-03-23; online 2017-03-23]

Affiliated researcher

PubMed DOI Crossref

NEArender: an R package for functional interpretation of 'omics' data via network enrichment analysis.

Jeggari A, Alexeyenko A

BMC Bioinformatics 18 (Suppl 5) 118 [2017-03-23; online 2017-03-23]

Affiliated researcher

PubMed DOI Crossref

Modeling and Targeting MYC Genes in Childhood Brain Tumors.

Hutter S, Bolin S, Weishaupt H, Swartling FJ

Genes (Basel) 8 (4) - [2017-03-23; online 2017-03-23]

Affiliated researcher

PubMed DOI Crossref

Furan- and Thiophene-Based Auxochromes Red-shift Chlorin Absorptions and Enable Oxidative Chlorin Polymerizations.

Xiong R, Bornhof AB, Arkhypchuk AI, Orthaber A, Borbas KE

Chemistry 23 (17) 4089-4095 [2017-03-23; online 2017-01-23]

Ruisheng Xiong SciLifeLab Fellow

PubMed DOI Crossref

A Preliminary Report: Radical Surgery and Stem Cell Transplantation for the Treatment of Patients With Pancreatic Cancer.

Omazic B, Ayoglu B, Löhr M, ..., Maeurer MJ, Ringden O

J. Immunother. - (-) - [2017-03-23; online 2017-03-23]

Affiliated researcher

PubMed DOI Crossref

Quantification of HER2 and estrogen receptor heterogeneity in breast cancer by single-molecule RNA fluorescence in situ hybridization.

Annaratone L, Simonetti M, Wernersson E, ..., Sapino A, Crosetto N

Oncotarget 8 (12) 18680-18698 [2017-03-21; online 2017-04-21]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Helicobacter pylori eradication in the Swedish population.

Doorakkers E, Lagergren J, Gajulapuri VK, ..., Engstrand L, Brusselaers N

Scand. J. Gastroenterol. 52 (6-7) 678-685 [2017-03-21; online 2017-03-21]

Affiliated researcher

PubMed DOI Crossref

Electrochemical Genetic Profiling of Single Cancer Cells.

Acero Sánchez JL, Joda H, Henry OY, ..., Latta D, O'Sullivan CK

Anal. Chem. 89 (6) 3378-3385 [2017-03-21; online 2017-02-28]

Affiliated researcher

PubMed DOI Crossref

Analysis of spatial heterogeneity in normal epithelium and preneoplastic alterations in mouse prostate tumor models.

Valkonen M, Ruusuvuori P, Kartasalo K, ..., Visakorpi T, Latonen L

Sci Rep 7 (-) 44831 [2017-03-20; online 2017-03-20]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.

Blondiaux N, Moune M, Desroses M, ..., Willand N, Baulard AR

Science 355 (6330) 1206-1211 [2017-03-17; online 2017-03-16]

Affiliated researcher

PubMed DOI Crossref

Proteogenomics produces comprehensive and highly accurate protein-coding gene annotation in a complete genome assembly of Malassezia sympodialis.

Zhu Y, Engström PG, Tellgren-Roth C, ..., Scheynius A, Lehtiö J

Nucleic Acids Res. 45 (5) 2629-2643 [2017-03-17; online 2017-01-20]

Affiliated researcher

PubMed DOI Crossref

PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c.

Pan G, Ameur A, Enroth S, ..., Gyllensten U, Wadelius C

Nucleic Acids Res. 45 (5) 2408-2422 [2017-03-17; online 2016-12-10]

Affiliated researcher

PubMed DOI Crossref

Ligand Discovery for a Peptide-Binding GPCR by Structure-Based Screening of Fragment- and Lead-Like Chemical Libraries.

Ranganathan A, Heine P, Rudling A, ..., Kummer L, Carlsson J

ACS chemical biology 12 (3) 735-745 [2017-03-17; online 2017-01-24]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Inflammation boosts bacteriophage transfer between Salmonella spp.

Diard M, Bakkeren E, Cornuault JK, ..., Slack E, Hardt WD

Science (New York, N.Y.) 355 (6330) 1211-1215 [2017-03-17; online 2017-03-16]

Affiliated researcher Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Identification of endoribonuclease specific cleavage positions reveals novel targets of RNase III in Streptococcus pyogenes.

Le Rhun A, Lécrivain AL, Reimegård J, ..., Della Beffa C, Charpentier E

Nucleic Acids Res. 45 (5) 2329-2340 [2017-03-17; online 2017-01-14]

Affiliated researcher

PubMed DOI Crossref

Late Danubian mitochondrial genomes shed light into the Neolithisation of Central Europe in the 5

Chyleński M, Juras A, Ehler E, ..., Marciniak A, Dabert M

BMC Evol Biol BMC Evolutionary Biology 17 (1) 80 [2017-03-16; online 2017-03-16]

Affiliated researcher

PubMed DOI Crossref

The atypical Rho GTPase RhoD is a regulator of actin cytoskeleton dynamics and directed cell migration.

Blom M, Reis K, Heldin J, Kreuger J, Aspenström P

Exp. Cell Res. 352 (2) 255-264 [2017-03-15; online 2017-02-11]

Affiliated researcher

PubMed DOI Crossref

Safe and Effective Treatment of Experimental Neuroblastoma and Glioblastoma Using Systemically Delivered Triple MicroRNA-Detargeted Oncolytic Semliki Forest Virus

Ramachandran M, Yu D, Dyczynski M, ..., Leja-Jarblad J, Essand M

Clin. Cancer Res. 23 (6) 1519-1530 [2017-03-15; online 2016-09-16]

Affiliated researcher

PubMed DOI Crossref

Revertant mosaicism repairs skin lesions in a patient with keratitis-ichthyosis-deafness syndrome by second-site mutations in connexin 26.

Gudmundsson S, Wilbe M, Ekvall S, ..., Törmä H, Bondeson ML

Hum. Mol. Genet. 26 (6) 1070-1077 [2017-03-15; online 2017-02-06]

Affiliated researcher

PubMed DOI Crossref

Total biosynthesis of the cyclic AMP booster forskolin from

Pateraki I, Andersen-Ranberg J, Jensen NB, ..., Møller BL, Hamberger B

Elife 6 (-) - [2017-03-14; online 2017-03-14]

Affiliated researcher

PubMed DOI Crossref

Microbial community assembly and evolution in subseafloor sediment.

Starnawski P, Bataillon T, Ettema TJ, ..., Schramm A, Kjeldsen KU

Proc. Natl. Acad. Sci. U.S.A. 114 (11) 2940-2945 [2017-03-14; online 2017-02-27]

Affiliated researcher

PubMed DOI Crossref

Comparison of Implicit and Explicit Solvent Models for the Calculation of Solvation Free Energy in Organic Solvents.

Zhang J, Zhang H, Wu T, Wang Q, van der Spoel D

J Chem Theory Comput 13 (3) 1034-1043 [2017-03-14; online 2017-03-06]

Affiliated researcher

PubMed DOI Crossref

TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation.

Nakano N, Tsuchiya Y, Kako K, ..., Ten Dijke P, Itoh S

J. Biol. Chem. 292 (10) 4099-4112 [2017-03-10; online 2017-01-23]

Affiliated researcher

PubMed DOI Crossref

Immunogenicity is preferentially induced in sparse dendritic cell cultures.

Nasi A, Bollampalli VP, Sun M, ..., Rothfuchs AG, Réthi B

Sci Rep 7 (-) 43989 [2017-03-09; online 2017-03-09]

Affiliated researcher

PubMed DOI Crossref

Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.

Llona-Minguez S, Höglund A, Wiita E, ..., Scobie M, Helleday T

J. Med. Chem. 60 (5) 2148-2154 [2017-03-09; online 2017-02-15]

Affiliated researcher

PubMed DOI Crossref

Discovery of circulating proteins associated to knee radiographic osteoarthritis.

Lourido L, Ayoglu B, Fernández-Tajes J, ..., Nilsson P, Blanco FJ

Sci Rep 7 (1) 137 [2017-03-09; online 2017-03-09]

Affiliated researcher

PubMed DOI Crossref

Helicobacter pylori Adapts to Chronic Infection and Gastric Disease via pH-Responsive BabA-Mediated Adherence.

Bugaytsova JA, Björnham O, Chernov YA, ..., Berg DE, Borén T

Cell Host Microbe 21 (3) 376-389 [2017-03-08; online 2017-03-11]

Affiliated researcher

PubMed DOI Crossref

Emotional anticipation after delivery - a longitudinal neuroimaging study of the postpartum period.

Gingnell M, Toffoletto S, Wikström J, ..., Comasco E, Sundström-Poromaa I

Sci Rep 7 (1) 114 [2017-03-08; online 2017-03-08]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Systems Biology of Metabolism: A Driver for Developing Personalized and Precision Medicine.

Nielsen J

Cell Metab. 25 (3) 572-579 [2017-03-07; online 2017-03-09]

Affiliated researcher

PubMed DOI Crossref

Ancient X chromosomes reveal contrasting sex bias in Neolithic and Bronze Age Eurasian migrations.

Goldberg A, Günther T, Rosenberg NA, Jakobsson M

Proc. Natl. Acad. Sci. U.S.A. 114 (10) 2657-2662 [2017-03-07; online 2017-02-21]

Affiliated researcher

PubMed DOI Crossref

Whole-Proteome Peptide Microarrays for Profiling Autoantibody Repertoires within Multiple Sclerosis and Narcolepsy.

Zandian A, Forsström B, Häggmark-Månberg A, ..., Nilsson P, Ayoglu B

J. Proteome Res. 16 (3) 1300-1314 [2017-03-03; online 2017-02-09]

Affiliated researcher

PubMed DOI Crossref

A hybrid method for the imputation of genomic data in livestock populations.

Antolín R, Nettelblad C, Gorjanc G, Money D, Hickey JM

Genet. Sel. Evol. 49 (1) 30 [2017-03-03; online 2017-03-03]

Affiliated researcher

PubMed DOI Crossref

Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD.

Mardinoglu A, Bjornson E, Zhang C, ..., Taskinen MR, Boren J

Mol Syst Biol 13 (3) 916 [2017-03-02; online 2017-03-02]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

The application of microbeads to microfluidic systems for enhanced detection and purification of biomolecules.

Pinto IF, Caneira CR, Soares RR, ..., Azevedo AM, Chu V

Methods 116 (-) 112-124 [2017-03-01; online 2016-12-10]

Affiliated researcher

PubMed DOI Crossref

The XChemExplorer graphical workflow tool for routine or large-scale protein-ligand structure determination.

Krojer T, Talon R, Pearce N, ..., Marsden B, von Delft F

Acta Crystallogr D Struct Biol 73 (Pt 3) 267-278 [2017-03-01; online 2017-02-24]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

Proper modelling of ligand binding requires an ensemble of bound and unbound states.

Pearce NM, Krojer T, von Delft F

Acta Crystallogr D Struct Biol 73 (Pt 3) 256-266 [2017-03-01; online 2017-03-06]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

Gentle, fast and effective crystal soaking by acoustic dispensing.

Collins PM, Ng JT, Talon R, ..., Pearce NM, von Delft F

Acta Crystallogr D Struct Biol 73 (Pt 3) 246-255 [2017-03-01; online 2017-03-06]

DDLS Fellow Nicholas Pearce

PubMed DOI Crossref

Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.

Ma R, Karthik GM, Lövrot J, ..., Fredriksson I, Hartman J

J. Natl. Cancer Inst. 109 (3) 1-14 [2017-03-01; online 2017-04-05]

Affiliated researcher

PubMed DOI Crossref

Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays.

Larssen P, Wik L, Czarnewski P, ..., Gabrielsson S, Kamali-Moghaddam M

Mol. Cell Proteomics 16 (3) 502-511 [2017-03-00; online 2017-01-22]

Affiliated researcher

PubMed DOI Crossref

The use of a Swedish telephone medical advice service by the elderly - a population-based study.

Dahlgren K, Holzmann MJ, Carlsson AC, ..., Hasselström J, Ruge T

Scand J Prim Health Care 35 (1) 98-104 [2017-03-00; online 2017-03-03]

Affiliated researcher

PubMed DOI Crossref

T cells in chronic lymphocytic leukemia display dysregulated expression of immune checkpoints and activation markers.

Palma M, Gentilcore G, Heimersson K, ..., Österborg A, Mellstedt H

Haematologica 102 (3) 562-572 [2017-03-00; online 2016-12-07]

Affiliated researcher

PubMed DOI Crossref

Prevalence of autism and attention-deficit-hyperactivity disorder in Down syndrome: a population-based study.

Oxelgren UW, Myrelid Å, Annerén G, ..., Gustafsson J, Fernell E

Dev Med Child Neurol 59 (3) 276-283 [2017-03-00; online 2016-08-09]

Affiliated researcher

PubMed DOI Crossref

Physiological and gene expression responses to nitrogen regimes and temperatures in Mastigocladus sp. strain CHP1, a predominant thermotolerant cyanobacterium of hot springs.

Alcamán ME, Alcorta J, Bergman B, ..., Polz M, Díez B

Syst. Appl. Microbiol. 40 (2) 102-113 [2017-03-00; online 2016-12-28]

Affiliated researcher

PubMed DOI Crossref

Phylogenetic analysis of

Barbosa RN, Leong SL, Vinnere-Pettersson O, ..., Oliveira NT, Houbraken J

Stud. Mycol. 86 (-) 29-51 [2017-03-00; online 2017-04-12]

Affiliated researcher

PubMed DOI Crossref

Pancreatic Fat Is Associated With Metabolic Syndrome and Visceral Fat but Not Beta-Cell Function or Body Mass Index in Pediatric Obesity.

Staaf J, Labmayr V, Paulmichl K, ..., Weghuber D, Kullberg J

Pancreas 46 (3) 358-365 [2017-03-00; online 2016-12-13]

Affiliated researcher

PubMed DOI Crossref

Overexpression of heparanase attenuated TGF-β-stimulated signaling in tumor cells.

Batool T, Fang J, Barash U, ..., Vlodavsky I, Li JP

FEBS Open Bio 7 (3) 405-413 [2017-03-00; online 2017-02-11]

Affiliated researcher

PubMed DOI Crossref

Metapopulation theory identifies biogeographical patterns among core and satellite marine bacteria scaling from tens to thousands of kilometers.

Lindh MV, Sjöstedt J, Ekstam B, ..., Legrand C, Pinhassi J

Environ. Microbiol. 19 (3) 1222-1236 [2017-03-00; online 2017-02-06]

Affiliated researcher DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Human ROBO1 regulates white matter structure in corpus callosum.

Darki F, Massinen S, Salmela E, ..., Klingberg T, Kere J

Brain Struct Funct 222 (2) 707-716 [2017-03-00; online 2016-05-30]

Affiliated researcher

PubMed DOI Crossref

High GC content causes orphan proteins to be intrinsically disordered.

Basile W, Sachenkova O, Light S, Elofsson A

PLoS Comput Biol 13 (3) e1005375 [2017-03-00; online 2017-03-29]

Affiliated researcher

PubMed DOI Crossref

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

Warren HR, Evangelou E, Cabrera CP, ..., International Genomics of Blood Pressure (iGEN-BP) Consortium , UK Biobank CardioMetabolic Consortium BP working group

Nat. Genet. 49 (3) 403-415 [2017-03-00; online 2017-01-30]

Affiliated researcher

PubMed DOI Crossref

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Wain LV, Shrine N, Artigas MS, ..., Hall IP, Tobin MD

Nat. Genet. 49 (3) 416-425 [2017-03-00; online 2017-02-06]

Affiliated researcher

PubMed DOI Crossref

Ethanol affects limbic and striatal presynaptic glutamatergic and DNA methylation gene expression in outbred rats exposed to early-life stress.

Vrettou M, Granholm L, Todkar A, ..., Nylander I, Comasco E

Addict Biol 22 (2) 369-380 [2017-03-00; online 2015-11-27]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Development of a novel therapeutic vaccine carrier that sustains high antibody titers against several targets simultaneously.

Saupe F, Reichel M, Huijbers EJ, ..., Hellman LT, Olsson AK

FASEB J. 31 (3) 1204-1214 [2017-03-00; online 2016-12-19]

Affiliated researcher SciLifeLab Fellow Sebastian Deindl

PubMed DOI Crossref

Development of [

Stepanov V, Svedberg M, Jia Z, ..., Nordberg A, Halldin C

Nucl. Med. Biol. 46 (-) 50-53 [2017-03-00; online 2016-12-09]

Affiliated researcher

PubMed DOI Crossref

DNA methylation profiling of pediatric B-cell lymphoblastic leukemia with KMT2A rearrangement identifies hypomethylation at enhancer sites.

Bergmann AK, Castellano G, Alten J, ..., Schrappe M, Siebert R

Pediatr Blood Cancer 64 (3) - [2017-03-00; online 2016-10-27]

Affiliated researcher

PubMed DOI Crossref

Cotranslational folding of spectrin domains via partially structured states.

Nilsson OB, Nickson AA, Hollins JJ, ..., von Heijne G, Clarke J

Nat. Struct. Mol. Biol. 24 (3) 221-225 [2017-03-00; online 2017-01-23]

Affiliated researcher

PubMed DOI Crossref

Biomimetic spinning of artificial spider silk from a chimeric minispidroin.

Andersson M, Jia Q, Abella A, ..., Johansson J, Rising A

Nat. Chem. Biol. 13 (3) 262-264 [2017-03-00; online 2017-01-09]

Affiliated researcher

PubMed DOI Crossref

Association of Pregnancy Complications and Characteristics With Future Risk of Elevated Blood Pressure: The Västerbotten Intervention Program.

Parikh NI, Norberg M, Ingelsson E, ..., Jansson JH, Edstedt Bonamy AK

Hypertension 69 (3) 475-483 [2017-03-00; online 2017-01-30]

Affiliated researcher

PubMed DOI Crossref

Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis ‬.

Zeitelhofer M, Adzemovic MZ, Gomez-Cabrero D, ..., Guerreiro-Cacais AO, Jagodic M

Proc. Natl. Acad. Sci. U.S.A. 114 (9) E1678-E1687 [2017-02-28; online 2017-02-14]

Affiliated researcher

DOI Crossref

Measuring true localization accuracy in super resolution microscopy with DNA-origami nanostructures

Reuss M, Fördős F, Blom H, ..., Högberg B, Brismar H

New J. Phys. 19 (2) 025013 [2017-02-27; online 2017-02-27]

Affiliated researcher

PubMed DOI Crossref

Genome-wide effects of MELK-inhibitor in triple-negative breast cancer cells indicate context-dependent response with p53 as a key determinant.

Simon M, Mesmar F, Helguero L, Williams C

PLoS ONE 12 (2) e0172832 [2017-02-24; online 2017-02-24]

Affiliated researcher

PubMed DOI Crossref

Epitopes of anti-RIFIN antibodies and characterization of rif-expressing Plasmodium falciparum parasites by RNA sequencing.

Ch'ng JH, Sirel M, Zandian A, ..., Qundos U, Wahlgren M

Sci Rep 7 (-) 43190 [2017-02-24; online 2017-02-24]

Affiliated researcher

PubMed DOI Crossref

Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors.

Thorsell AG, Ekblad T, Karlberg T, ..., Cohen MS, Schüler H

J. Med. Chem. 60 (4) 1262-1271 [2017-02-23; online 2016-12-21]

Affiliated researcher

PubMed DOI Crossref

Imatinib increases oxygen delivery in extracellular matrix-rich but not in matrix-poor experimental carcinoma.

Burmakin M, van Wieringen T, Olsson PO, ..., Rubin K, Hellberg C

J Transl Med 15 (1) 47 [2017-02-23; online 2017-02-23]

Affiliated researcher

PubMed DOI Crossref

Intracellular drug bioavailability: a new predictor of system dependent drug disposition.

Mateus A, Treyer A, Wegler C, ..., Matsson P, Artursson P

Sci Rep 7 (-) 43047 [2017-02-22; online 2017-02-22]

Affiliated researcher

PubMed DOI Crossref

Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease.

Borroto-Escuela DO, Carlsson J, Ambrogini P, ..., Diaz-Cabiale Z, Fuxe K

Front. Cell. Neurosci. 11 (-) 37 [2017-02-21; online 2017-02-21]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo.

Alkasalias T, Alexeyenko A, Hennig K, ..., Gad AK, Pavlova T

Proc. Natl. Acad. Sci. U.S.A. 114 (8) E1413-E1421 [2017-02-21; online 2017-02-07]

Affiliated researcher

PubMed DOI Crossref

Application of Noncanonical Amino Acids for Protein Labeling in a Genomically Recoded Escherichia coli.

Kipper K, Lundius EG, Ćurić V, ..., Lemke EA, Elf J

ACS Synth. Biol. 6 (2) 233-255 [2017-02-17; online 2016-11-23]

Affiliated researcher

PubMed DOI Crossref

Comparison of whole genome amplification techniques for human single cell exome sequencing.

Borgström E, Paterlini M, Mold JE, Frisen J, Lundeberg J

PLoS ONE 12 (2) e0171566 [2017-02-16; online 2017-02-16]

Affiliated researcher

PubMed DOI Crossref

Uncertainty estimation of predictions of peptides' chromatographic retention times in shotgun proteomics.

Maboudi Afkham H, Qiu X, The M, Käll L

Bioinformatics 33 (4) 508-513 [2017-02-15; online 2016-11-03]

Affiliated researcher

PubMed DOI Crossref

Nitration of MOG diminishes its encephalitogenicity depending on MHC haplotype.

Warnecke A, Musunuri S, N'diaye M, ..., Bergquist J, Harris RA

J. Neuroimmunol. 303 (-) 1-12 [2017-02-15; online 2016-11-26]

Affiliated researcher

PubMed DOI Crossref

Genital Injury Signatures and Microbiome Alterations Associated With Depot Medroxyprogesterone Acetate Usage and Intravaginal Drying Practices.

Birse KD, Romas LM, Guthrie BL, ..., Broliden K, Burgener AD

J. Infect. Dis. 215 (4) 590-598 [2017-02-15; online 2016-12-25]

Affiliated researcher

PubMed DOI Crossref

Delineating Amyloid Plaque Associated Neuronal Sphingolipids in Transgenic Alzheimer's Disease Mice (tgArcSwe) Using MALDI Imaging Mass Spectrometry.

Kaya I, Brinet D, Michno W, ..., Blennow K, Hanrieder J

ACS Chem Neurosci 8 (2) 347-355 [2017-02-15; online 2017-01-10]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor.

Gustafsson R, Jemth AS, Gustafsson NM, ..., Helleday T, Stenmark P

Cancer Res. 77 (4) 937-948 [2017-02-15; online 2016-11-29]

Affiliated researcher

PubMed DOI Crossref

The Baltic Sea Virome: Diversity and Transcriptional Activity of DNA and RNA Viruses.

Zeigler Allen L, McCrow JP, Ininbergs K, ..., Bergman B, Venter JC

mSystems 2 (1) - [2017-02-14; online 2017-02-14]

Affiliated researcher

PubMed DOI Crossref

Concomitant underexpression of TGFBR2 and overexpression of hTERT are associated with poor prognosis in cervical cancer.

Yang H, Zhang H, Zhong Y, ..., Zhou F, Zhou Y

Sci Rep 7 (-) 41670 [2017-02-14; online 2017-02-14]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

A novel RNA sequencing data analysis method for cell line authentication.

Fasterius E, Raso C, Kennedy S, ..., Uhlén M, Al-Khalili Szigyarto C

PLoS ONE 12 (2) e0171435 [2017-02-13; online 2017-02-13]

Affiliated researcher

PubMed DOI Crossref

Genetic and Functional Study of L-Type Amino Acid Transporter 1 in Schizophrenia.

Comasco E, Vumma R, Toffoletto S, ..., Jönsson EG, Venizelos N

Neuropsychobiology 74 (2) 96-103 [2017-02-11; online 2017-02-11]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

VMCMC: a graphical and statistical analysis tool for Markov chain Monte Carlo traces.

Ali RH, Bark M, Miró J, ..., Abbas RM, Arvestad L

BMC Bioinformatics 18 (1) 97 [2017-02-10; online 2017-02-10]

Affiliated researcher

PubMed DOI Crossref

Nanometer resolution imaging and tracking of fluorescent molecules with minimal photon fluxes.

Balzarotti F, Eilers Y, Gwosch KC, ..., Elf J, Hell SW

Science 355 (6325) 606-612 [2017-02-10; online 2016-12-22]

Affiliated researcher

PubMed DOI Crossref

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

Schütte M, Risch T, Abdavi-Azar N, ..., Lehrach H, Yaspo ML

Nat Commun 8 (-) 14262 [2017-02-10; online 2017-02-10]

Affiliated researcher

PubMed DOI Crossref

microRNAs with AAGUGC seed motif constitute an integral part of an oncogenic signaling network.

Zhou Y, Frings O, Branca RM, ..., Agami R, Orre LM

Oncogene 36 (6) 731-745 [2017-02-09; online 2016-08-01]

Affiliated researcher

PubMed DOI Crossref

Rare and low-frequency coding variants alter human adult height.

Marouli E, Graff M, Medina-Gomez C, ..., Deloukas P, Lettre G

Nature 542 (7640) 186-190 [2017-02-09; online 2017-02-01]

Affiliated researcher

PubMed DOI Crossref

Molecular composition of organic matter controls methylmercury formation in boreal lakes.

Bravo AG, Bouchet S, Tolu J, ..., Mateos-Rivera A, Bertilsson S

Nat Commun 8 (-) 14255 [2017-02-09; online 2017-02-09]

Affiliated researcher

PubMed DOI Crossref

The internal cranial anatomy of Romundina stellina Ørvig, 1975 (Vertebrata, Placodermi, Acanthothoraci) and the origin of jawed vertebrates-Anatomical atlas of a primitive gnathostome.

Dupret V, Sanchez S, Goujet D, Ahlberg PE

PLoS ONE 12 (2) e0171241 [2017-02-07; online 2017-02-07]

Affiliated researcher

PubMed DOI Crossref

EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions.

Alzrigat M, Párraga AA, Agarwal P, ..., Kalushkova A, Jernberg-Wiklund H

Oncotarget 8 (6) 10213-10224 [2017-02-07; online 2017-01-05]

Affiliated researcher

PubMed DOI Crossref

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.

Law PJ, Berndt SI, Speedy HE, ..., Houlston R, Slager S

Nat Commun 8 (-) 14175 [2017-02-06; online 2017-02-06]

Affiliated researcher

PubMed DOI Crossref

The structure of the yeast mitochondrial ribosome.

Desai N, Brown A, Amunts A, Ramakrishnan V

Science (New York, N.Y.) 355 (6324) 528-531 [2017-02-03; online 2017-02-06]

Affiliated researcher Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Seasonal Variation in Abundance and Diversity of Bacterial Methanotrophs in Five Temperate Lakes.

Samad MS, Bertilsson S

Front Microbiol 8 (-) 142 [2017-02-03; online 2017-02-03]

Affiliated researcher

PubMed DOI Crossref

Posttranscriptional Regulation in Adenovirus Infected Cells.

Zhao H, Konzer A, Mi J, ..., Pettersson U, Lind SB

J. Proteome Res. 16 (2) 872-888 [2017-02-03; online 2016-12-13]

Affiliated researcher

PubMed DOI Crossref

A Synthesis of "Dual Warhead" β-Aryl Ethenesulfonyl Fluorides and One-Pot Reaction to β-Sultams.

Chinthakindi PK, Govender KB, Kumar AS, ..., Naicker T, Arvidsson PI

Org. Lett. 19 (3) 480-483 [2017-02-03; online 2017-01-11]

Affiliated researcher

PubMed DOI Crossref

Variation in Mutational Robustness between Different Proteins and the Predictability of Fitness Effects.

Lind PA, Arvidsson L, Berg OG, Andersson DI

Mol. Biol. Evol. 34 (2) 408-418 [2017-02-01; online 2016-12-28]

Affiliated researcher

PubMed DOI Crossref

The Human Adrenal Gland Proteome Defined by Transcriptomics and Antibody-Based Profiling.

Bergman J, Botling J, Fagerberg L, ..., Uhlén M, Pontén F

Endocrinology 158 (2) 239-251 [2017-02-01; online 2016-12-03]

Affiliated researcher

PubMed DOI Crossref

Prokaryotic ubiquitin-like protein remains intrinsically disordered when covalently attached to proteasomal target proteins.

Barandun J, Damberger FF, Delley CL, ..., Allain FH, Weber-Ban E

BMC Struct. Biol. 17 (1) 1 [2017-02-01; online 2017-02-01]

Jonas Barandun SciLifeLab Fellow

PubMed DOI Crossref

Mouse Models of Pediatric Supratentorial High-grade Glioma Reveal How Cell-of-Origin Influences Tumor Development and Phenotype.

Sreedharan S, Maturi NP, Xie Y, ..., Swartling FJ, Uhrbom L

Cancer Res. 77 (3) 802-812 [2017-02-01; online 2016-11-15]

Affiliated researcher

PubMed DOI Crossref

Massive parallel sequencing questions the pathogenic role of missense variants in dilated cardiomyopathy.

Dalin MG, Engström PG, Ivarsson EG, ..., Andersson B, Bergo MO

Int. J. Cardiol. 228 (-) 742-748 [2017-02-01; online 2016-11-09]

Affiliated researcher

PubMed DOI Crossref

Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels.

Sennblad B, Basu S, Mazur J, ..., Trégouët DA, Sabater-Lleal M

Hum. Mol. Genet. 26 (3) 637-649 [2017-02-01; online 2017-01-06]

Affiliated researcher

PubMed DOI Crossref

Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB).

De Rosa M, Lu L, Zamaratski E, ..., Mowbray SL, Karlén A

Bioorg. Med. Chem. 25 (3) 897-911 [2017-02-01; online 2016-12-07]

Affiliated researcher

PubMed DOI Crossref

Clinical and Immunological Characteristics of Autoimmune Addison Disease: A Nationwide Swedish Multicenter Study.

Dalin F, Nordling Eriksson G, Dahlqvist P, ..., Kämpe O, Bensing S

J. Clin. Endocrinol. Metab. 102 (2) 379-389 [2017-02-01; online 2016-11-22]

Affiliated researcher

PubMed DOI Crossref

Clinical Characterization of Patients With Autosomal Dominant Short Stature due to Aggrecan Mutations.

Gkourogianni A, Andrew M, Tyzinski L, ..., Nilsson O, Dauber A

J. Clin. Endocrinol. Metab. 102 (2) 460-469 [2017-02-01; online 2016-11-22]

Affiliated researcher

PubMed DOI Crossref

Whole-Genome Sequencing of Cytogenetically Balanced Chromosome Translocations Identifies Potentially Pathological Gene Disruptions and Highlights the Importance of Microhomology in the Mechanism of Formation.

Nilsson D, Pettersson M, Gustavsson P, ..., Carvalho CMB, Lindstrand A

Hum. Mutat. 38 (2) 180-192 [2017-02-00; online 2016-12-05]

Affiliated researcher

PubMed DOI Crossref

The terpene synthase gene family in Tripterygium wilfordii harbors a labdane-type diterpene synthase among the monoterpene synthase TPS-b subfamily.

Hansen NL, Heskes AM, Hamberger B, ..., Andersen-Ranberg J, Hamberger B

Plant J. 89 (3) 429-441 [2017-02-00; online 2017-02-14]

Affiliated researcher

PubMed DOI Crossref

Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies.

Herold N, Rudd SG, Ljungblad L, ..., Helleday T, Schaller T

Nat. Med. 23 (2) 256-263 [2017-02-00; online 2017-01-09]

Affiliated researcher

PubMed DOI Crossref

Self-correcting mismatches during high-fidelity DNA replication.

Fernandez-Leiro R, Conrad J, Yang JC, ..., Scheres SH, Lamers MH

Nat. Struct. Mol. Biol. 24 (2) 140-143 [2017-02-00; online 2017-01-09]

Affiliated researcher

PubMed DOI Crossref

Robust, universal biomarker assay to detect senescent cells in biological specimens.

Evangelou K, Lougiakis N, Rizou SV, ..., Bartek J, Gorgoulis VG

Aging Cell 16 (1) 192-197 [2017-02-00; online 2016-11-17]

Affiliated researcher

PubMed DOI Crossref

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Schmidt AF, Swerdlow DI, Holmes MV, ..., Hingorani AD, Sattar N

The Lancet Diabetes & Endocrinology 5 (2) 97-105 [2017-02-00; online 2017-02-00]

Affiliated researcher

PubMed DOI Crossref

Opioid precursor protein isoform is targeted to the cell nuclei in the human brain.

Kononenko O, Bazov I, Watanabe H, ..., Yakovleva T, Bakalkin G

Biochim Biophys Acta Gen Subj 1861 (2) 246-255 [2017-02-00; online 2016-11-10]

Affiliated researcher

PubMed DOI Crossref

Multifractal Characterization of Pharmaceutical Hot-Melt Extrudates.

Adler C, Teleki A, Kuentz M

Pharm. Res. 34 (2) 321-332 [2017-02-00; online 2016-11-14]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

Mosaicism in health and disease - clones picking up speed.

Forsberg LA, Gisselsson D, Dumanski JP

Nat. Rev. Genet. 18 (2) 128-142 [2017-02-00; online 2016-12-12]

Affiliated researcher

PubMed DOI Crossref

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.

Romanov RA, Zeisel A, Bakker J, ..., Horvath TL, Harkany T

Nat. Neurosci. 20 (2) 176-188 [2017-02-00; online 2016-12-19]

Affiliated researcher

PubMed DOI Crossref

Metabolic Syndrome Development During Aging with Special Reference to Obesity Without the Metabolic Syndrome.

Roos V, Elmståhl S, Ingelsson E, ..., Ärnlöv J, Lind L

Metab Syndr Relat Disord 15 (1) 36-43 [2017-02-00; online 2016-10-18]

Affiliated researcher

PubMed DOI Crossref

Meta-omic analyses of Baltic Sea cyanobacteria: diversity, community structure and salt acclimation.

Celepli N, Sundh J, Ekman M, ..., Bergman B, Ininbergs K

Environ. Microbiol. 19 (2) 673-686 [2017-02-00; online 2017-01-27]

Affiliated researcher

PubMed DOI Crossref

Mercury Human Exposure in Populations Living Around Lake Tana (Ethiopia).

Habiba G, Abebe G, Bravo AG, ..., Staffan Ǻ, Bishop K

Biol Trace Elem Res 175 (2) 237-243 [2017-02-00; online 2016-06-09]

Affiliated researcher

PubMed DOI Crossref

Identification of new TRIP12 variants and detailed clinical evaluation of individuals with non-syndromic intellectual disability with or without autism.

Bramswig NC, Lüdecke HJ, Pettersson M, ..., Kleefstra T, Wieczorek D

Hum. Genet. 136 (2) 179-192 [2017-02-00; online 2016-11-15]

Affiliated researcher

PubMed DOI Crossref

Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population.

Hallberg P, Persson M, Axelsson T, ..., Eriksson N, Wadelius M

Pharmacogenomics 18 (3) 201-213 [2017-02-00; online 2017-01-13]

Affiliated researcher

PubMed DOI Crossref

Dwarfism and Altered Craniofacial Development in Rabbits Is Caused by a 12.1 kb Deletion at the HMGA2 Locus.

Carneiro M, Hu D, Archer J, ..., Rubin CJ, Andersson L

Genetics 205 (2) 955-965 [2017-02-00; online 2016-12-16]

Affiliated researcher

PubMed DOI Crossref

Crop-to-wild gene flow and its fitness consequences for a wild fruit tree: Towards a comprehensive conservation strategy of the wild apple in Europe.

Feurtey A, Cornille A, Shykoff JA, Snirc A, Giraud T

Evol Appl 10 (2) 180-188 [2017-02-00; online 2016-12-26]

Affiliated researcher

PubMed DOI Crossref

Antigen receptor stereotypy in chronic lymphocytic leukemia.

Stamatopoulos K, Agathangelidis A, Rosenquist R, Ghia P

Leukemia 31 (2) 282-291 [2017-02-00; online 2016-11-04]

Affiliated researcher

PubMed DOI Crossref

Activation of myeloid and endothelial cells by CD40L gene therapy supports T-cell expansion and migration into the tumor microenvironment.

Eriksson E, Moreno R, Milenova I, ..., Alemany R, Loskog A

Gene Ther. 24 (2) 92-103 [2017-02-00; online 2016-12-01]

Affiliated researcher

PubMed DOI Crossref

A meta-analysis of reflux genome-wide association studies in 6750 Northern Europeans from the general population.

Bonfiglio F, Hysi PG, Ek W, ..., Schmidt PT, D'Amato M

Neurogastroenterol. Motil. 29 (2) - [2017-02-00; online 2016-08-03]

Affiliated researcher

PubMed DOI Crossref

Towards encoded particles for highly multiplexed colorimetric point of care autoantibody detection.

Svedberg G, Jeong Y, Na H, ..., Gantelius J, Svahn HA

Lab Chip 17 (3) 549-556 [2017-01-31; online 2017-01-20]

Affiliated researcher

PubMed DOI Crossref

Predicting growth of the healthy infant using a genome scale metabolic model.

Nilsson A, Mardinoglu A, Nielsen J

NPJ Syst Biol Appl 3 (1) 3 [2017-01-31; online 2017-01-31]

Adil Mardinoglu Avlant Nilsson SciLifeLab Fellow

PubMed DOI Crossref

Genomic analysis reveals major determinants of cis-regulatory variation in Capsella grandiflora.

Steige KA, Laenen B, Reimegård J, Scofield DG, Slotte T

Proc. Natl. Acad. Sci. U.S.A. 114 (5) 1087-1092 [2017-01-31; online 2017-01-17]

Affiliated researcher SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Active Site Hydrophobicity and the Convergent Evolution of Paraoxonase Activity in Structurally Divergent Enzymes: The Case of Serum Paraoxonase 1.

Blaha-Nelson D, Krüger DM, Szeler K, Ben-David M, Kamerlin SC

J. Am. Chem. Soc. 139 (3) 1155-1167 [2017-01-25; online 2017-01-11]

Affiliated researcher

PubMed DOI Crossref

A novel method for crosstalk analysis of biological networks: improving accuracy of pathway annotation.

Ogris C, Guala D, Helleday T, Sonnhammer EL

Nucleic Acids Res. 45 (2) e8 [2017-01-25; online 2016-09-22]

Affiliated researcher

PubMed DOI Crossref

c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas.

Heiland DH, Ferrarese R, Claus R, ..., Nelander S, Carro MS

Oncotarget 8 (4) 6940-6954 [2017-01-24; online 2016-12-31]

Affiliated researcher

PubMed DOI Crossref

Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin.

Jiang Y, Marinescu VD, Xie Y, ..., Nelander S, Uhrbom L

Cell Reports 18 (4) 977-990 [2017-01-24; online 2017-01-26]

Affiliated researcher

PubMed DOI Crossref

Vimentin Levels and Serine 71 Phosphorylation in the Control of Cell-Matrix Adhesions, Migration Speed, and Shape of Transformed Human Fibroblasts.

Terriac E, Coceano G, Mavajian Z, ..., Lautenschläger F, Gad AK

Cells 6 (1) 2 [2017-01-22; online 2017-01-22]

Affiliated researcher Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Affibody Scaffolds Improve Sesquiterpene Production in Saccharomyces cerevisiae.

Tippmann S, Anfelt J, David F, ..., Nielsen J, Hudson EP

ACS Synth. Biol. 6 (1) 19-28 [2017-01-20; online 2016-08-30]

Affiliated researcher Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

Asgard archaea illuminate the origin of eukaryotic cellular complexity.

Zaremba-Niedzwiedzka K, Caceres EF, Saw JH, ..., Spang A, Ettema TJ

Nature 541 (7637) 353-358 [2017-01-19; online 2017-01-11]

Affiliated researcher

PubMed DOI Crossref

Novel genetic loci associated with hippocampal volume.

Hibar DP, Adams HHH, Jahanshad N, ..., Thompson PM, Ikram MA

Nat Commun 8 (-) 13624 [2017-01-18; online 2017-01-18]

Affiliated researcher

PubMed DOI Crossref

Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging.

Zanni G, Michno W, Di Martino E, ..., Blomgren K, Hanrieder J

Sci Rep 7 (-) 40726 [2017-01-18; online 2017-01-18]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Targeted DNA sequencing and in situ mutation analysis using mobile phone microscopy.

Kühnemund M, Wei Q, Darai E, ..., Ozcan A, Nilsson M

Nat Commun 8 (-) 13913 [2017-01-17; online 2017-01-17]

Affiliated researcher

PubMed DOI Crossref

Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion.

Sokolova M, Turunen M, Mortusewicz O, ..., Helleday T, Taipale J

Cell Cycle 16 (2) 189-199 [2017-01-17; online 2016-12-08]

Affiliated researcher

PubMed DOI Crossref

Cell of Origin Links Histotype Spectrum to Immune Microenvironment Diversity in Non-small-Cell Lung Cancer Driven by Mutant Kras and Loss of Lkb1.

Nagaraj AS, Lahtela J, Hemmes A, ..., Närhi K, Verschuren EW

Cell Reports 18 (3) 673-684 [2017-01-17; online 2017-01-19]

Affiliated researcher

PubMed DOI Crossref

Ameloblastoma RNA profiling uncovers a distinct non-coding RNA signature.

Davanian H, Balasiddaiah A, Heymann R, ..., Kruger Weiner C, Chen M

Oncotarget 8 (3) 4530-4542 [2017-01-17; online 2016-12-15]

Affiliated researcher

PubMed DOI Crossref

Architecture of the yeast small subunit processome.

Chaker-Margot M, Barandun J, Hunziker M, Klinge S

Science 355 (6321) - [2017-01-13; online 2016-12-15]

Jonas Barandun SciLifeLab Fellow

DOI Crossref

Rituximab capping triggers intracellular reorganization of B cells

Koller T, Blok S, Santos AM, ..., Sezgin E, Eggeling C

Matters - (-) - [2017-01-12; online 2017-01-12]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

New insights into the GINS complex explain the controversy between existing structural models.

Carroni M, De March M, Medagli B, ..., Patwardhan A, Onesti S

Sci Rep 7 (-) 40188 [2017-01-10; online 2017-01-10]

Affiliated researcher

PubMed DOI Crossref

Major transitions in dinoflagellate evolution unveiled by phylotranscriptomics.

Janouškovec J, Gavelis GS, Burki F, ..., Rohwer FL, Saldarriaga JF

Proc. Natl. Acad. Sci. U.S.A. 114 (2) E171-E180 [2017-01-10; online 2016-12-27]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Development of Cell-Permeable, Non-Helical Constrained Peptides to Target a Key Protein-Protein Interaction in Ovarian Cancer.

Wiedmann MM, Tan YS, Wu Y, ..., Brenton JD, Spring DR

Angew. Chem. Int. Ed. Engl. 56 (2) 524-529 [2017-01-09; online 2016-12-05]

Affiliated researcher

PubMed DOI Crossref

Identification of a Novel Autoimmune Peptide Epitope of Prostein in Prostate Cancer.

Pin E, Henjes F, Hong MG, ..., Nilsson P, Schwenk JM

J. Proteome Res. 16 (1) 204-216 [2017-01-06; online 2016-10-24]

Affiliated researcher

PubMed DOI Crossref

Antibody Validation in Bioimaging Applications Based on Endogenous Expression of Tagged Proteins.

Skogs M, Stadler C, Schutten R, ..., Uhlén M, Lundberg E

J. Proteome Res. 16 (1) 147-155 [2017-01-06; online 2016-10-26]

Affiliated researcher

PubMed DOI Crossref

Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.

Kee N, Volakakis N, Kirkeby A, ..., Parmar M, Perlmann T

Cell Stem Cell 20 (1) 29-40 [2017-01-05; online 2016-10-27]

Affiliated researcher

PubMed DOI Crossref

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

Wahl S, Drong A, Lehne B, ..., Grallert H, Chambers JC

Nature 541 (7635) 81-86 [2017-01-05; online 2016-12-21]

Affiliated researcher

PubMed DOI Crossref

HieranoiDB: a database of orthologs inferred by Hieranoid.

Kaduk M, Riegler C, Lemp O, Sonnhammer EL

Nucleic Acids Res. 45 (D1) D687-D690 [2017-01-04; online 2016-10-13]

Affiliated researcher

PubMed DOI Crossref

DisProt 7.0: a major update of the database of disordered proteins.

Piovesan D, Tabaro F, Mičetić I, ..., Tompa P, Tosatto SC

Nucleic Acids Res. 45 (D1) D219-D227 [2017-01-04; online 2016-11-28]

Affiliated researcher

PubMed DOI Crossref

A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma.

Gremel G, Djureinovic D, Niinivirta M, ..., Stewart GD, Pontén F

BMC Cancer 17 (1) 9 [2017-01-04; online 2017-01-04]

Affiliated researcher

PubMed DOI Crossref

TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells.

Brattås PL, Jönsson ME, Fasching L, ..., Parmar M, Jakobsson J

Cell Reports 18 (1) 1-11 [2017-01-03; online 2017-01-05]

Affiliated researcher

PubMed DOI Crossref

Sex differences in depression during pregnancy and the postpartum period.

Sundström Poromaa I, Comasco E, Georgakis MK, Skalkidou A

J Neurosci Res 95 (1-2) 719-730 [2017-01-02; online 2016-11-22]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Comprehensive RNA sequencing of healthy human endometrium at two time points of the menstrual cycle.

Sigurgeirsson B, Åmark H, Jemt A, ..., Lundeberg J, Gidlöf S

Biol. Reprod. 96 (1) 24-33 [2017-01-01; online 2017-04-11]

Affiliated researcher

PubMed DOI Crossref

CADEE: Computer-Aided Directed Evolution of Enzymes.

Amrein BA, Steffen-Munsberg F, Szeler I, ..., Kulkarni Y, Kamerlin SCL

IUCrJ 4 (Pt 1) 50-64 [2017-01-01; online 2017-01-01]

Affiliated researcher

PubMed DOI Crossref

Associations between a polymorphism in the hydroxysteroid (11-beta) dehydrogenase 1 gene, neuroticism and postpartum depression.

Iliadis SI, Comasco E, Hellgren C, ..., Sundström Poromaa I, Skalkidou A

J Affect Disord 207 (-) 141-147 [2017-01-01; online 2016-09-26]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Why mitochondria need a genome revisited.

Björkholm P, Ernst AM, Hagström E, Andersson SG

FEBS Lett. 591 (1) 65-75 [2017-01-00; online 2016-12-20]

Affiliated researcher

PubMed DOI Crossref

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

Thuresson AC, Van Buggenhout G, Sheth F, ..., Clayton Smith J, Soussi Zander C

Clin. Genet. 91 (1) 106-110 [2017-01-00; online 2016-06-02]

Affiliated researcher

PubMed DOI Crossref

Transcriptional Dynamics During Human Adipogenesis and Its Link to Adipose Morphology and Distribution.

Ehrlund A, Mejhert N, Björk C, ..., Arner P, Arner E

Diabetes 66 (1) 218-230 [2017-01-00; online 2016-11-01]

Affiliated researcher

PubMed DOI Crossref

Targeting TGF-β Signaling in Cancer.

Colak S, Ten Dijke P

Trends Cancer 3 (1) 56-71 [2017-01-00; online 2017-01-03]

Affiliated researcher

PubMed DOI Crossref

Systemic lupus erythematosus: still a challenge for physicians.

Bengtsson AA, Rönnblom L

J. Intern. Med. 281 (1) 52-64 [2017-01-00; online 2016-06-16]

Affiliated researcher

PubMed DOI Crossref

Region-specific bioconversion of dynorphin neuropeptide detected by in situ histochemistry and MALDI imaging mass spectrometry.

Bivehed E, Strömvall R, Bergquist J, Bakalkin G, Andersson M

Peptides 87 (-) 20-27 [2017-01-00; online 2016-11-10]

Affiliated researcher

PubMed DOI Crossref

Nano-liquid Chromatography-orbitrap MS-based Quantitative Proteomics Reveals Differences Between the Mechanisms of Action of Carnosic Acid and Carnosol in Colon Cancer Cells.

Valdés A, García-Cañas V, Artemenko KA, ..., Bergquist J, Cifuentes A

Mol. Cell Proteomics 16 (1) 8-22 [2017-01-00; online 2016-11-10]

Affiliated researcher

PubMed DOI Crossref

Mutational analysis of protein folding inside the ribosome exit tunnel.

Farías-Rico JA, Goetz SK, Marino J, von Heijne G

FEBS Lett. 591 (1) 155-163 [2017-01-00; online 2016-12-20]

Affiliated researcher

PubMed DOI Crossref

Multispecies genetic structure and hybridization in the Betula genus across Eurasia.

Tsuda Y, Semerikov V, Sebastiani F, Vendramin GG, Lascoux M

Mol. Ecol. 26 (2) 589-605 [2017-01-00; online 2016-12-24]

Affiliated researcher

PubMed DOI Crossref

Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation.

Chu AY, Deng X, Fisher VA, ..., Steinhauser ML, Fox CS

Nat. Genet. 49 (1) 125-130 [2017-01-00; online 2016-12-05]

Affiliated researcher

PubMed DOI Crossref

Modulation of the molecular arrangement in artificial and biological membranes by phospholipid-shelled microbubbles.

Carugo D, Aron M, Sezgin E, ..., Eggeling C, Stride E

Biomaterials 113 (-) 105-117 [2017-01-00; online 2016-10-24]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Heinonen S, Muniandy M, Buzkova J, ..., Rissanen A, Pietiläinen KH

Diabetologia 60 (1) 169-181 [2017-01-00; online 2016-10-12]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

DOI Crossref

Lake bacterioplankton dynamics over diurnal timescales

Grubisic LM, Bertilsson S, Eiler A, ..., Riemann L, Beier S

Freshw Biol 62 (1) 191-204 [2017-01-00; online 2016-12-16]

Affiliated researcher

PubMed DOI Crossref

Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity.

Kegel ME, Johansson V, Wetterberg L, ..., Hultman CM, Erhardt S

Psychiatry Res 247 (-) 105-112 [2017-01-00; online 2016-11-16]

Affiliated researcher

PubMed DOI Crossref

Investigating kinship of Neolithic post-LBK human remains from Krusza Zamkowa, Poland using ancient DNA.

Juras A, Chyleński M, Krenz-Niedbała M, ..., Jakobsson M, Dabert M

Forensic Sci Int Genet 26 (-) 30-39 [2017-01-00; online 2016-10-14]

Affiliated researcher

PubMed DOI Crossref

Induction of the 5S RNP-Mdm2-p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia.

Jaako P, Ugale A, Wahlestedt M, ..., Lindström MS, Bryder D

Leukemia 31 (1) 213-221 [2017-01-00; online 2016-06-03]

Affiliated researcher

PubMed DOI Crossref

Human immune system variation.

Brodin P, Davis MM

Nat. Rev. Immunol. 17 (1) 21-29 [2017-01-00; online 2016-12-05]

Affiliated researcher

PubMed DOI Crossref

Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p'-dde levels in a population-based sample.

Lind L, Ng E, Ingelsson E, ..., Morris AP, Lind PM

Environ Int 98 (-) 212-218 [2017-01-00; online 2016-11-11]

Affiliated researcher

PubMed DOI Crossref

Flow-cytometric screening of aggregation-inhibitors using a fluorescence-assisted intracellular method.

Lindberg H, Sandersjöö L, Meister SW, ..., Löfblom J, Ståhl S

Biotechnol J 12 (1) - [2017-01-00; online 2016-12-01]

Affiliated researcher

PubMed DOI Crossref

Expression of possible targets for new proteasome inhibitors in diffuse large B-cell lymphoma.

Delforoush M, Berglund M, Edqvist PH, ..., Gullbo J, Enblad G

Eur. J. Haematol. 98 (1) 52-56 [2017-01-00; online 2016-07-12]

Affiliated researcher

PubMed DOI Crossref

Evolutionary engineering reveals divergent paths when yeast is adapted to different acidic environments.

Fletcher E, Feizi A, Bisschops MMM, ..., Siewers V, Nielsen J

Metab. Eng. 39 (-) 19-28 [2017-01-00; online 2016-11-02]

Affiliated researcher

PubMed DOI Crossref

Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies.

Hedman ÅK, Mendelson MM, Marioni RE, ..., Levy D, Ingelsson E

Circ Cardiovasc Genet 10 (1) - [2017-01-00; online 2017-02-19]

Affiliated researcher

PubMed DOI Crossref

Environmental Risk Factors for Diabetes Mellitus in Cats.

Öhlund M, Egenvall A, Fall T, ..., Röcklinsberg H, Holst BS

J. Vet. Intern. Med. 31 (1) 29-35 [2017-01-00; online 2016-12-01]

Affiliated researcher

PubMed DOI Crossref

Elevated levels of circulating CDH5 and FABP1 in association with human drug-induced liver injury.

Mikus M, Drobin K, Gry M, ..., Nilsson P, Schuppe-Koistinen I

Liver Int. 37 (1) 132-140 [2017-01-00; online 2016-06-22]

Affiliated researcher

PubMed DOI Crossref

Droplet size influences division of mammalian cell factories in droplet microfluidic cultivation.

Periyannan Rajeswari PK, Joensson HN, Andersson-Svahn H

Electrophoresis 38 (2) 305-310 [2017-01-00; online 2016-09-12]

Affiliated researcher

PubMed DOI Crossref

Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.

Häggblad Sahlberg S, Mortensen AC, Haglöf J, ..., Stenerlöw B, Nestor M

Int. J. Oncol. 50 (1) 5-14 [2017-01-00; online 2016-11-18]

Affiliated researcher

PubMed DOI Crossref

Deep Fish.

Ishaq O, Sadanandan SK, Wählby C

SLAS Discov 22 (1) 102-107 [2017-01-00; online 2016-09-26]

Affiliated researcher

PubMed DOI Crossref

DNA sequence diversity and the efficiency of natural selection in animal mitochondrial DNA.

James J, Castellano D, Eyre-Walker A

Heredity (Edinb) 118 (1) 88-95 [2017-01-00; online 2016-11-09]

Jennifer James

PubMed DOI Crossref

Cost and clinical outcome of islet transplantation in Norway 2010-2015.

Schive SW, Foss A, Sahraoui A, ..., Mishra V, Scholz H

Clin Transplant 31 (1) - [2017-01-00; online 2016-12-09]

Affiliated researcher

PubMed DOI Crossref

Circulating levels of perfluoroalkyl substances (PFASs) and carotid artery atherosclerosis.

Lind PM, Salihovic S, van Bavel B, Lind L

Environ. Res. 152 (-) 157-164 [2017-01-00; online 2016-10-20]

Affiliated researcher

PubMed DOI Crossref

Both maternal and offspring Elovl2 genotypes determine systemic DHA levels in perinatal mice.

Pauter AM, Trattner S, Gonzalez-Bengtsson A, ..., Dethlefsen O, Jacobsson A

J. Lipid Res. 58 (1) 111-123 [2017-01-00; online 2016-11-18]

Affiliated researcher

PubMed DOI Crossref

A multi-step peptidolytic cascade for amino acid recovery in chloroplasts.

Teixeira PF, Kmiec B, Branca RM, ..., Lehtiö J, Glaser E

Nat. Chem. Biol. 13 (1) 15-17 [2017-01-00; online 2016-10-31]

Affiliated researcher

PubMed DOI Crossref

Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients

Niinivirta M, Enblad G, Edqvist PH, ..., Dragomir A, Ullenhag GJ

J. Cancer 8 (19) 3975-3983 [2017-00-00; online 2017-00-00]

Affiliated researcher

DOI Crossref

The Convoluted Evolution of Eukaryotes With Complex Plastids

Burki F

- - (-) 1-30 [2017-00-00; online 2017-00-00]

Affiliated researcher Fabien Burki SciLifeLab Fellow

DOI Crossref

Structure-Based Discovery of GPCR Ligands from Crystal Structures and Homology Models

Ranganathan A, Rodríguez D, Carlsson J

- - (-) 65-99 [2017-00-00; online 2017-05-25]

Jens Carlsson SciLifeLab Fellow

DOI Crossref

Slipdisc: a versatile sample preparation platform for point of care diagnostics

Banerjee I, Salih T, Ramachandraiah H, ..., Karlsson M, Russom A

RSC Adv. 7 (56) 35048-35054 [2017-00-00; online 2017-00-00]

Affiliated researcher

DOI Crossref

Photodynamic therapy targeting VCAM-1-expressing human umbilical vein endothelial cells using a PpIX–VCAM-1 binding peptide–quantum dot conjugate

Yin H, Shi X, Wang H, ..., Li Y, Fu Y

RSC Adv. 7 (80) 50562-50570 [2017-00-00; online 2017-00-00]

Affiliated researcher

DOI Crossref

Morphology and histology of acanthodian fin spines from the late Silurian Ramsåsa E locality, Skåne, Swede

Jerve A, Bremer O, Sanchez S, Ahlberg P

- - (-) - [2017-00-00; online 2017-00-00]

Affiliated researcher

DOI Crossref

Long Non Coding RNA Biology

Springer [book] (-) - [2017-00-00; online 2017-00-00]

SciLifeLab Fellow Vicent Pelechano

DOI Crossref

Lignin depolymerization to monophenolic compounds in a flow-through system

Kumaniaev I, Subbotina E, Sävmarker J, ..., Galkin MV, Samec JSM

Green Chem. 19 (24) 5767-5771 [2017-00-00; online 2017-00-00]

Affiliated researcher

DOI Crossref

Inertial microfluidics combined with selective cell lysis for high throughput separation of nucleated cells from whole blood

Ramachandraiah H, Svahn HA, Russom A

RSC Adv. 7 (47) 29505-29514 [2017-00-00; online 2017-00-00]

Affiliated researcher

DOI Crossref

Evolution of Resistance to Insecticide in Disease Vectors

Labbé P, David JP, Alout H, ..., Pasteur N, Weill M

- - (-) 313-339 [2017-00-00; online 2017-00-00]

Pascal Milesi SciLifeLab Fellow

DOI Crossref

Bridging chemical- and bio-catalysis: high-value liquid transportation fuel production from renewable agricultural residues

Xue C, Liu M, Guo X, ..., Liu F, Yang ST

Green Chem. 19 (3) 660-669 [2017-00-00; online 2017-00-00]

Paul Hudson SciLifeLab Fellow

DOI Crossref

Biodegradative activities of fungal isolates from plastic contaminated soils

El-Morsy E

Mycosphere 8 (8) 1071-1087 [2017-00-00; online 2017-00-00]

Affiliated researcher

DOI Crossref

A Computable Measure of Algorithmic Probability by Finite Approximations with an Application to Integer Sequences

Soler-Toscano F, Zenil H

Complexity 2017 (-) 1-10 [2017-00-00; online 2017-00-00]

Affiliated researcher

PubMed DOI Crossref

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol.

Schmidt A, Éliás S, Joshi RN, Tegnér J

J Vis Exp - (118) - [2016-12-30; online 2016-12-30]

Affiliated researcher

PubMed DOI Crossref

The Chd1 chromatin remodeler shifts hexasomes unidirectionally.

Levendosky RF, Sabantsev A, Deindl S, Bowman GD

Elife 5 (-) - [2016-12-29; online 2016-12-29]

Affiliated researcher SciLifeLab Fellow Sebastian Deindl

DOI Crossref

Photon Reabsorption and Nonradiative Energy-Transfer-Induced Quenching of Blue Photoluminescence from Aggregated Graphene Quantum Dots

Gan Z, Xu H, Fu Y

J. Phys. Chem. C 120 (51) 29432-29438 [2016-12-29; online 2016-12-20]

Affiliated researcher

PubMed DOI Crossref

On the role of water density fluctuations in the inhibition of a proton channel.

Gianti E, Delemotte L, Klein ML, Carnevale V

Proc. Natl. Acad. Sci. U.S.A. 113 (52) E8359-E8368 [2016-12-27; online 2016-12-12]

Affiliated researcher Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

miR-203 and miR-320 Regulate Bone Morphogenetic Protein-2-Induced Osteoblast Differentiation by Targeting Distal-Less Homeobox 5 (Dlx5).

Laxman N, Mallmin H, Nilsson O, Kindmark A

Genes (Basel) 8 (1) - [2016-12-23; online 2016-12-23]

Affiliated researcher

PubMed DOI Crossref

TGF-β Affects the Differentiation of Human GM-CSF

Éliás S, Schmidt A, Kannan V, Andersson J, Tegnér J

Front Immunol 7 (-) 603 [2016-12-23; online 2016-12-23]

Affiliated researcher

PubMed DOI Crossref

Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity.

Corcoran MM, Phad GE, Vázquez Bernat , ..., Martin M, Karlsson Hedestam GB

Nat Commun 7 (-) 13642 [2016-12-20; online 2016-12-20]

Affiliated researcher

PubMed DOI Crossref

Pickering and Network Stabilization of Biocompatible Emulsions Using Chitosan-Modified Silica Nanoparticles.

Alison L, Rühs PA, Tervoort E, ..., Isa L, Studart AR

Langmuir 32 (50) 13446-13457 [2016-12-20; online 2016-12-09]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

The spliceosome U2 snRNP factors promote genome stability through distinct mechanisms; transcription of repair factors and R-loop processing.

Tanikawa M, Sanjiv K, Helleday T, Herr P, Mortusewicz O

Oncogenesis 5 (12) e280 [2016-12-19; online 2016-12-19]

Affiliated researcher

PubMed DOI Crossref

Potential Involvement of Type I Interferon Signaling in Immunotherapy in Seasonal Allergic Rhinitis.

Mattson L, Lentini A, Gawel DR, ..., Xiang Z, Zhang H

J Immunol Res 2016 (-) 5153184 [2016-12-19; online 2016-12-19]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

Copy number variability of expression plasmids determined by cell sorting and Droplet Digital PCR.

Jahn M, Vorpahl C, Hübschmann T, Harms H, Müller S

Microb Cell Fact 15 (1) 211 [2016-12-19; online 2016-12-19]

Affiliated researcher

PubMed DOI Crossref

Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia.

Pandzic T, Larsson J, He L, ..., Sjöblom T, Hellström M

Clin. Cancer Res. 22 (24) 6217-6227 [2016-12-15; online 2016-03-08]

Affiliated researcher

PubMed DOI Crossref

The genome of Rhizobiales bacteria in predatory ants reveals urease gene functions but no genes for nitrogen fixation.

Neuvonen MM, Tamarit D, Näslund K, ..., Guy L, Andersson SG

Sci Rep 6 (-) 39197 [2016-12-15; online 2016-12-15]

Affiliated researcher

PubMed DOI Crossref

Novel SACS mutations associated with intellectual disability, epilepsy and widespread supratentorial abnormalities.

Ali Z, Klar J, Jameel M, ..., Baig S, Dahl N

J. Neurol. Sci. 371 (-) 105-111 [2016-12-15; online 2016-10-21]

Affiliated researcher

PubMed DOI Crossref

Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior.

Cornelis MC, Kacprowski T, Menni C, ..., Grabe HJ, Ingelsson E

Hum. Mol. Genet. 25 (24) 5472-5482 [2016-12-15; online 2016-10-06]

Affiliated researcher

PubMed DOI Crossref

Genetic Variants in CHIA and CHI3L1 Are Associated with the IgE Response to the Ascaris Resistance Marker ABA-1 and the Birch Pollen Allergen Bet v 1.

Acevedo N, Bornacelly A, Mercado D, ..., Scheynius A, Caraballo L

PLoS ONE 11 (12) e0167453 [2016-12-15; online 2016-12-15]

Affiliated researcher

PubMed DOI Crossref

FANCM c.5101C>T mutation associates with breast cancer survival and treatment outcome.

Kiiski JI, Fagerholm R, Tervasmäki A, ..., Blomqvist C, Nevanlinna H

Int. J. Cancer 139 (12) 2760-2770 [2016-12-15; online 2016-09-19]

Affiliated researcher

PubMed DOI Crossref

The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.

van Kempen LC, Redpath M, Elchebly M, ..., Feunteun J, Spatz A

Sci Transl Med 8 (369) 369ra177 [2016-12-14; online 2016-12-16]

Affiliated researcher

PubMed DOI Crossref

The In Vitro Stability of Circulating Tumour DNA.

Henao Diaz E, Yachnin J, Grönberg H, Lindberg J

PLoS ONE 11 (12) e0168153 [2016-12-13; online 2016-12-13]

Affiliated researcher

PubMed DOI Crossref

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference.

Schumann G, Liu C, O'Reilly P, ..., Levy D, Elliott P

Proc. Natl. Acad. Sci. U.S.A. 113 (50) 14372-14377 [2016-12-13; online 2016-11-28]

Affiliated researcher

PubMed DOI Crossref

Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition.

Segerman A, Niklasson M, Haglund C, ..., Segerman B, Westermark B

Cell Reports 17 (11) 2994-3009 [2016-12-13; online 2016-12-16]

Affiliated researcher

PubMed DOI Crossref

Serum Autoantibody Profiling of Patients with Paraneoplastic and Non-Paraneoplastic Autoimmune Retinopathy.

Ten Berge JC, van Rosmalen J, Vermeer J, ..., Rothova A, Schreurs MW

PLoS ONE 11 (12) e0167909 [2016-12-08; online 2016-12-08]

Affiliated researcher

PubMed DOI Crossref

PDGFB, a new candidate plasma biomarker for venous thromboembolism: results from the VEREMA affinity proteomics study.

Bruzelius M, Iglesias MJ, Hong MG, ..., Trégouët DA, Odeberg J

Blood 128 (23) e59-e66 [2016-12-08; online 2016-10-14]

Affiliated researcher

PubMed DOI Crossref

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.

Mansouri L, Noerenberg D, Young E, ..., Rosenquist R, Damm F

Blood 128 (23) 2666-2670 [2016-12-08; online 2016-09-26]

Affiliated researcher

PubMed DOI Crossref

Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells.

Zhang L, Laaniste L, Jiang Y, ..., Uhrbom L, Dimberg A

Oncotarget 7 (49) 80382-80390 [2016-12-06; online 2016-11-03]

Affiliated researcher

PubMed DOI Crossref

Membrane Anchoring and Ion-Entry Dynamics in P-type ATPase Copper Transport.

Grønberg C, Sitsel O, Lindahl E, Gourdon P, Andersson M

Biophys. J. 111 (11) 2417-2429 [2016-12-06; online 2016-12-08]

Affiliated researcher

PubMed DOI Crossref

Karyotypic complexity rather than chromosome 8 abnormalities aggravates the outcome of chronic lymphocytic leukemia patients with TP53 aberrations.

Blanco G, Puiggros A, Baliakas P, ..., Stamatopoulos K, Espinet B

Oncotarget 7 (49) 80916-80924 [2016-12-06; online 2016-11-09]

Affiliated researcher

PubMed DOI Crossref

hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia.

Eshtad S, Mavajian Z, Rudd SG, ..., Altun M, Helleday T

Oncogenesis 5 (12) e275 [2016-12-05; online 2016-12-05]

Affiliated researcher

PubMed DOI Crossref

The Effect of Moment of Inertia on the Liquids in Centrifugal Microfluidics.

Pishbin E, Eghbal M, Fakhari S, Kazemzadeh A, Navidbakhsh M

Micromachines (Basel) 7 (12) - [2016-12-02; online 2016-12-02]

Affiliated researcher

PubMed DOI Crossref

Role of DNA Repair Factor Xeroderma Pigmentosum Protein Group C in Response to Replication Stress As Revealed by DNA Fragile Site Affinity Chromatography and Quantitative Proteomics.

Beresova L, Vesela E, Chamrad I, ..., Mistrik M, Bartek J

J. Proteome Res. 15 (12) 4505-4517 [2016-12-02; online 2016-11-09]

Affiliated researcher

PubMed DOI Crossref

The topogenic function of S4 promotes membrane insertion of the voltage-sensor domain in the KvAP channel.

Mishima E, Sato Y, Nanatani K, ..., Sakaguchi M, Uozumi N

Biochem. J. 473 (23) 4361-4372 [2016-12-01; online 2016-09-30]

Affiliated researcher

PubMed DOI Crossref

Quantitative and Selective Analysis of Feline Growth Related Proteins Using Parallel Reaction Monitoring High Resolution Mass Spectrometry.

Sundberg M, Strage EM, Bergquist J, Holst BS, Ramström M

PLoS ONE 11 (12) e0167138 [2016-12-01; online 2016-12-01]

Affiliated researcher

PubMed DOI Crossref

FARAO: the flexible all-round annotation organizer.

Hammarén R, Pal C, Bengtsson-Palme J

Bioinformatics 32 (23) 3664-3666 [2016-12-01; online 2016-08-04]

Affiliated researcher DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Elucidating selection processes for antibiotic resistance in sewage treatment plants using metagenomics.

Bengtsson-Palme J, Hammarén R, Pal C, ..., Tysklind M, Larsson DGJ

Sci. Total Environ. 572 (-) 697-712 [2016-12-01; online 2016-08-17]

Affiliated researcher DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Validation and development of MTH1 inhibitors for treatment of cancer.

Warpman Berglund U, Sanjiv K, Gad H, ..., Scobie M, Helleday T

Ann. Oncol. 27 (12) 2275-2283 [2016-12-00; online 2016-11-08]

Affiliated researcher

PubMed DOI Crossref

The disappearing San of southeastern Africa and their genetic affinities.

Schlebusch CM, Prins F, Lombard M, Jakobsson M, Soodyall H

Hum. Genet. 135 (12) 1365-1373 [2016-12-00; online 2016-09-20]

Affiliated researcher

PubMed DOI Crossref

The ace-1 Locus Is Amplified in All Resistant Anopheles gambiae Mosquitoes: Fitness Consequences of Homogeneous and Heterogeneous Duplications.

Assogba BS, Milesi P, Djogbénou LS, ..., Labbé P, Weill M

PLoS Biol. 14 (12) e2000618 [2016-12-00; online 2016-12-05]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Synthesis of 11C-labeled Sulfonyl Carbamates through a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols, and [11C]CO.

Stevens MY, Chow SY, Estrada S, ..., Åberg O, Odell LR

ChemistryOpen 5 (6) 566-573 [2016-12-00; online 2016-10-05]

Affiliated researcher

PubMed DOI Crossref

Structural and conformational determinants of macrocycle cell permeability.

Over B, Matsson P, Tyrchan C, ..., Duvall JR, Kihlberg J

Nat. Chem. Biol. 12 (12) 1065-1074 [2016-12-00; online 2016-10-17]

Affiliated researcher

PubMed DOI Crossref

Squalene-hopene cyclases-evolution, dynamics and catalytic scope.

Syrén PO, Henche S, Eichler A, Nestl BM, Hauer B

Curr. Opin. Struct. Biol. 41 (-) 73-82 [2016-12-00; online 2016-06-20]

Affiliated researcher

PubMed DOI Crossref

Novel genetic loci underlying human intracranial volume identified through genome-wide association.

Adams HH, Hibar DP, Chouraki V, ..., Ikram MA, Thompson PM

Nat. Neurosci. 19 (12) 1569-1582 [2016-12-00; online 2016-10-03]

Affiliated researcher

DOI Crossref

Improvement in Mechanical Performance of Anionic Hydrogels Using Full-Interpenetrating Polymer Network Reinforced with Graphene Oxide Nanosheets

KHEIRABADI M, BAGHERI R, KABIRI K, ..., JOKAR E, ASADIAN E

Adv Polym Technol 35 (4) 386-395 [2016-12-00; online 2016-10-05]

Affiliated researcher

PubMed DOI Crossref

Higher chylomicron remnants and LDL particle numbers associate with CD36 SNPs and DNA methylation sites that reduce CD36.

Love-Gregory L, Kraja AT, Allum F, ..., Grundberg E, Abumrad NA

J. Lipid Res. 57 (12) 2176-2184 [2016-12-00; online 2016-10-11]

Affiliated researcher

PubMed DOI Crossref

Heparanase Promotes Glioma Progression and Is Inversely Correlated with Patient Survival.

Kundu S, Xiong A, Spyrou A, ..., Li JP, Forsberg-Nilsson K

Mol. Cancer Res. 14 (12) 1243-1253 [2016-12-00; online 2016-08-26]

Affiliated researcher

PubMed DOI Crossref

Genome-wide analysis identifies 12 loci influencing human reproductive behavior.

Barban N, Jansen R, de Vlaming R, ..., Snieder H, Mills MC

Nat. Genet. 48 (12) 1462-1472 [2016-12-00; online 2016-10-31]

Affiliated researcher

PubMed DOI Crossref

Genes mirror migrations and cultures in prehistoric Europe-a population genomic perspective.

Günther T, Jakobsson M

Curr. Opin. Genet. Dev. 41 (-) 115-123 [2016-12-00; online 2016-09-27]

Affiliated researcher

PubMed DOI Crossref

Fourth Generation of Next-Generation Sequencing Technologies: Promise and Consequences.

Ke R, Mignardi M, Hauling T, Nilsson M

Hum. Mutat. 37 (12) 1363-1367 [2016-12-00; online 2016-08-10]

Affiliated researcher

PubMed DOI Crossref

Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease.

Eriksson D, Bianchi M, Landegren N, ..., Kämpe O, Pielberg GR

J. Intern. Med. 280 (6) 595-608 [2016-12-00; online 2016-11-02]

Affiliated researcher

PubMed DOI Crossref

Exploring the oviductal fluid proteome by a lectin-based affinity approach.

Yu H, Reiser J, Besenfelder U, ..., Artemenko K, Mayrhofer C

Proteomics 16 (23) 2962-2966 [2016-12-00; online 2016-11-09]

Affiliated researcher

PubMed DOI Crossref

Early Perspective.

Seashore-Ludlow B, Lundbäck T

J Biomol Screen 21 (10) 1019-1033 [2016-12-00; online 2016-07-20]

Affiliated researcher

PubMed DOI Crossref

Distribution and expression of microbial rhodopsins in the Baltic Sea and adjacent waters.

Brindefalk B, Ekman M, Ininbergs K, ..., Pinhassi J, Bergman B

Environ. Microbiol. 18 (12) 4442-4455 [2016-12-00; online 2016-07-14]

Affiliated researcher

PubMed DOI Crossref

Distance measurements in peridinin-chlorophyll a-protein by light-induced PELDOR spectroscopy. Analysis of triplet state localization.

Di Valentin M, Dal Farra MG, Galazzo L, ..., Hofmann E, Carbonera D

Biochim. Biophys. Acta 1857 (12) 1909-1916 [2016-12-00; online 2016-09-20]

Affiliated researcher

PubMed DOI Crossref

Computational metabolic engineering strategies for growth-coupled biofuel production by Synechocystis.

Shabestary K, Hudson EP

Metabolic engineering communications 3 (-) 216-226 [2016-12-00; online 2016-07-20]

Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

ClpAP is an auxiliary protease for DnaA degradation in Caulobacter crescentus.

Liu J, Francis LI, Jonas K, Laub MT, Chien P

Mol. Microbiol. 102 (6) 1075-1085 [2016-12-00; online 2016-10-17]

Affiliated researcher Kristina Jonas SciLifeLab Fellow

PubMed DOI Crossref

CSF profiling of the human brain enriched proteome reveals associations of neuromodulin and neurogranin to Alzheimer's disease.

Remnestål J, Just D, Mitsios N, ..., Nilsson P, Häggmark-Månberg A

Proteomics Clin Appl 10 (12) 1242-1253 [2016-12-00; online 2016-10-10]

Affiliated researcher

DOI Crossref

Base sequence specificity of counterion binding to DNA: what can MD simulations tell us?

Atzori A, Liggi S, Laaksonen A, ..., Saba G, Mocci F

Can. J. Chem. 94 (12) 1181-1188 [2016-12-00; online 2016-12-00]

Affiliated researcher

PubMed DOI Crossref

Allochthonous carbon is a major regulator to bacterial growth and community composition in subarctic freshwaters

Roiha T, Peura S, Cusson M, Rautio M

Sci Rep 6 (1) - [2016-12-00; online 2016-09-30]

Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish.

Varshney GK, Carrington B, Pei W, ..., Sood R, Burgess SM

Nat Protoc 11 (12) 2357-2375 [2016-12-00; online 2016-10-27]

Affiliated researcher

PubMed DOI Crossref

A SUMO and ubiquitin code coordinates protein traffic at replication factories.

Lecona E, Fernandez-Capetillo O

Bioessays 38 (12) 1209-1217 [2016-12-00; online 2016-09-26]

Affiliated researcher

PubMed DOI Crossref

A Kinase-Phosphatase Switch Transduces Environmental Information into a Bacterial Cell Cycle Circuit.

Heinrich K, Sobetzko P, Jonas K

PLoS Genet 12 (12) e1006522 [2016-12-00; online 2016-12-12]

Affiliated researcher Kristina Jonas SciLifeLab Fellow

PubMed DOI Crossref

Harnessing Yeast Peroxisomes for Biosynthesis of Fatty-Acid-Derived Biofuels and Chemicals with Relieved Side-Pathway Competition.

Zhou YJ, Buijs NA, Zhu Z, ..., Siewers V, Nielsen J

J. Am. Chem. Soc. 138 (47) 15368-15377 [2016-11-30; online 2016-10-31]

Affiliated researcher

PubMed DOI Crossref

A stromal cell population in the large intestine identified by tissue factor expression that is lost during colorectal cancer progression.

Eriksson O, Asplund A, Hegde G, ..., Pontén F, Siegbahn A

Thromb. Haemost. 116 (6) 1050-1059 [2016-11-30; online 2016-09-22]

Affiliated researcher

PubMed DOI Crossref

Identification of Shared and Unique Serum Lipid Profiles in Diabetes Mellitus and Myocardial Infarction.

Kjellqvist S, Klose C, Surma MA, ..., Melander O, Fernandez C

J Am Heart Assoc 5 (12) - [2016-11-29; online 2016-11-29]

Affiliated researcher

PubMed DOI Crossref

Duplication of chicken defensin7 gene generated by gene conversion and homologous recombination.

Lee MO, Bornelöv S, Andersson L, ..., Chen J, Womack JE

Proc. Natl. Acad. Sci. U.S.A. 113 (48) 13815-13820 [2016-11-29; online 2016-11-14]

Affiliated researcher

PubMed DOI Crossref

Habitat generalists and specialists in microbial communities across a terrestrial-freshwater gradient.

Monard C, Gantner S, Bertilsson S, Hallin S, Stenlid J

Sci Rep 6 (-) 37719 [2016-11-25; online 2016-11-25]

Affiliated researcher

PubMed DOI Crossref

DNA methylation patterns associated with oxidative stress in an ageing population.

Hedman ÅK, Zilmer M, Sundström J, Lind L, Ingelsson E

BMC Med Genomics 9 (1) 72 [2016-11-25; online 2016-11-25]

Affiliated researcher

PubMed DOI Crossref

Towards agile large-scale predictive modelling in drug discovery with flow-based programming design principles.

Lampa S, Alvarsson J, Spjuth O

J Cheminform 8 (-) 67 [2016-11-24; online 2016-11-24]

Affiliated researcher

PubMed DOI Crossref

Phylogenetic Signals of Salinity and Season in Bacterial Community Composition Across the Salinity Gradient of the Baltic Sea.

Herlemann DP, Lundin D, Andersson AF, Labrenz M, Jürgens K

Front Microbiol 7 (-) 1883 [2016-11-24; online 2016-11-24]

Affiliated researcher

PubMed DOI Crossref

Editorial: The Impact of Systems Medicine on Human Health and Disease.

Mardinoglu A, Nielsen J

Front. Physiol. 7 (-) 552 [2016-11-24; online 2016-11-24]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Abnormal primary and permanent dentitions with ectodermal symptoms predict WNT10A deficiency.

Bergendal B, Norderyd J, Zhou X, Klar J, Dahl N

BMC Med. Genet. 17 (1) 88 [2016-11-24; online 2016-11-24]

Affiliated researcher

PubMed DOI Crossref

From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration.

Gomez-Cabrero D, Menche J, Vargas C, ..., Roca J, Synergy-COPD Consortia

BMC Bioinformatics 17 (Suppl 15) 441 [2016-11-22; online 2016-11-22]

Affiliated researcher

PubMed DOI Crossref

Exploring Spatio-temporal Dynamics of Cellular Automata for Pattern Recognition in Networks.

Miranda GHB, Machicao J, Bruno OM

Sci Rep 6 (-) 37329 [2016-11-22; online 2016-11-22]

Gisele Miranda SciLifeLab Fellow

PubMed DOI Crossref

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.

Scharaw S, Iskar M, Ori A, ..., Bork P, Pepperkok R

J. Cell Biol. 215 (4) 543-558 [2016-11-21; online 2016-11-08]

Affiliated researcher

PubMed DOI Crossref

Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis.

Ernst C, Pike J, Aitken SJ, ..., Kutter C, Odom DT

Elife 5 (-) - [2016-11-18; online 2016-11-18]

Affiliated researcher Claudia Kutter SciLifeLab Fellow

DOI Crossref

Microwave Heated Continuous Flow Palladium(II)-Catalyzed Desulfitative Synthesis of Aryl Ketones

Skillinghaug B, Rydfjord J, Sävmarker J, Larhed M

Org. Process Res. Dev. 20 (11) 2005-2011 [2016-11-18; online 2016-11-00]

Affiliated researcher

PubMed DOI Crossref

ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer.

Magnusson K, Gremel G, Rydén L, ..., Jirström K, Pontén F

BMC Cancer 16 (1) 904 [2016-11-18; online 2016-11-18]

Affiliated researcher

PubMed DOI Crossref

An automated approach to prepare tissue-derived spatially barcoded RNA-sequencing libraries.

Jemt A, Salmén F, Lundmark A, ..., Yucel-Lindberg T, Lundeberg J

Sci Rep 6 (-) 37137 [2016-11-16; online 2016-11-16]

Affiliated researcher

PubMed DOI Crossref

Periostin is identified as a putative metastatic marker in breast cancer-derived exosomes.

Vardaki I, Ceder S, Rutishauser D, ..., Foukakis T, Panaretakis T

Oncotarget 7 (46) 74966-74978 [2016-11-15; online 2016-09-03]

Affiliated researcher

PubMed DOI Crossref

BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity.

Rasmussen RD, Gajjar MK, Tuckova L, ..., Frederiksen MH, Hamerlik P

Nat Commun 7 (-) 13398 [2016-11-15; online 2016-11-15]

Affiliated researcher

PubMed DOI Crossref

Adaptive Evolution of Phosphorus Metabolism in Prochlorococcus.

Casey JR, Mardinoglu A, Nielsen J, Karl DM

mSystems 1 (6) - [2016-11-15; online 2016-11-15]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2.

Kimanius D, Forsberg BO, Scheres SH, Lindahl E

Elife 5 (-) - [2016-11-15; online 2016-11-15]

Affiliated researcher

PubMed DOI Crossref

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis.

Gerstner C, Dubnovitsky A, Sandin C, ..., Achour A, Malmström V

Front Immunol 7 (-) 494 [2016-11-14; online 2016-11-14]

Affiliated researcher

PubMed DOI Crossref

Probing the mechanisms for the selectivity and promiscuity of methyl parathion hydrolase.

Purg M, Pabis A, Baier F, ..., Jackson C, Kamerlin SC

Philos Trans A Math Phys Eng Sci 374 (2080) - [2016-11-13; online 2016-10-05]

Affiliated researcher

PubMed DOI Crossref

A perspective on bridging scales and design of models using low-dimensional manifolds and data-driven model inference.

Tegnér J, Zenil H, Kiani NA, Ball G, Gomez-Cabrero D

Philos Trans A Math Phys Eng Sci 374 (2080) - [2016-11-13; online 2016-10-05]

Affiliated researcher

PubMed DOI Crossref

Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease.

Matsson H, Söderhäll C, Einarsdottir E, ..., Lundbäck B, Klar J

BMC Pulm Med 16 (1) 146 [2016-11-11; online 2016-11-11]

Affiliated researcher

PubMed DOI Crossref

Probabilistic inference of lateral gene transfer events.

Khan MA, Mahmudi O, Ullah I, Arvestad L, Lagergren J

BMC Bioinformatics 17 (Suppl 14) 431 [2016-11-11; online 2016-11-11]

Affiliated researcher

PubMed DOI Crossref

The stem osteichthyan Andreolepis and the origin of tooth replacement.

Chen D, Blom H, Sanchez S, Tafforeau P, Ahlberg PE

Nature 539 (7628) 237-241 [2016-11-10; online 2016-10-17]

Affiliated researcher

PubMed DOI Crossref

Cohort profile: the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC).

Jääskeläinen T, Heinonen S, Kajantie E, ..., Laivuori H, FINNPEC Study Group

BMJ Open 6 (11) e013148 [2016-11-10; online 2016-11-10]

Affiliated researcher

PubMed DOI Crossref

Immunohistochemical Typing of Adenocarcinomas of the Pancreatobiliary System Improves Diagnosis and Prognostic Stratification.

Fernández Moro C, Fernandez-Woodbridge A, Alistair D'souza M, ..., Verbeke C, Bozóky B

PLoS ONE 11 (11) e0166067 [2016-11-09; online 2016-11-09]

Affiliated researcher

PubMed DOI Crossref

PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.

Roodakker KR, Elsir T, Edqvist PD, ..., Malmström A, Smits A

Oncotarget 7 (45) 72431-72442 [2016-11-08; online 2016-09-15]

Affiliated researcher

PubMed DOI Crossref

Case-specific potentiation of glioblastoma drugs by pterostilbene.

Schmidt L, Baskaran S, Johansson P, ..., Krona C, Nelander S

Oncotarget 7 (45) 73200-73215 [2016-11-08; online 2016-10-01]

Affiliated researcher

PubMed DOI Crossref

Looking for Missing Proteins in the Proteome of Human Spermatozoa: An Update.

Vandenbrouck Y, Lane L, Carapito C, ..., Garin J, Pineau C

J. Proteome Res. 15 (11) 3998-4019 [2016-11-04; online 2016-08-23]

Affiliated researcher

PubMed DOI Crossref

Clonal B-cell lymphocytosis of marginal zone origin.

Xochelli A, Oscier D, Stamatopoulos K

Best Pract Res Clin Haematol 30 (1-2) 77-83 [2016-11-04; online 2016-11-04]

Affiliated researcher

PubMed DOI Crossref

Three-dimensional paleohistology of the scale and median fin spine of Lophosteus superbus (Pander 1856)

Jerve A, Qu Q, Sanchez S, Blom H, Ahlberg PE

PeerJ 4 (-) e2521 [2016-11-02; online 2016-11-02]

Affiliated researcher

PubMed DOI Crossref

Maps of context-dependent putative regulatory regions and genomic signal interactions.

Diamanti K, Umer HM, Kruczyk M, ..., Wadelius C, Komorowski J

Nucleic Acids Res. 44 (19) 9110-9120 [2016-11-02; online 2016-09-12]

Affiliated researcher

PubMed DOI Crossref

Tryptophan Metabolism Along the Kynurenine Pathway Downstream of Toll-like Receptor Stimulation in Peripheral Monocytes.

Orhan F, Bhat M, Sandberg K, ..., Erhardt S, Schwieler L

Scand. J. Immunol. 84 (5) 262-271 [2016-11-00; online 2016-10-27]

Affiliated researcher

PubMed DOI Crossref

The two Dps proteins, NpDps2 and NpDps5, are involved in light-induced oxidative stress tolerance in the N

Moparthi VK, Li X, Vavitsas K, ..., Magnuson A, Stensjö K

Biochim. Biophys. Acta 1857 (11) 1766-1776 [2016-11-00; online 2016-08-12]

Affiliated researcher

PubMed DOI Crossref

The H3 chaperone function of NASP is conserved in Arabidopsis.

Maksimov V, Nakamura M, Wildhaber T, ..., Bergquist J, Hennig L

Plant J. 88 (3) 425-436 [2016-11-00; online 2016-09-15]

Affiliated researcher

PubMed DOI Crossref

Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia.

Bereczki E, Francis PT, Howlett D, ..., Ballard C, Aarsland D

Alzheimers Dement 12 (11) 1149-1158 [2016-11-00; online 2016-05-22]

Affiliated researcher

PubMed DOI Crossref

Screening out irrelevant cell-based models of disease.

Horvath P, Aulner N, Bickle M, ..., von Schantz C, Carragher NO

Nat Rev Drug Discov 15 (11) 751-769 [2016-11-00; online 2016-09-12]

Affiliated researcher

DOI Crossref

Remediation and recycling of chromium from tannery wastewater using combined chemical–biological treatment system

Ahmed E, Abdulla HM, Mohamed AH, El-Bassuony AD

Process Safety and Environmental Protection 104 (-) 1-10 [2016-11-00; online 2016-11-00]

Affiliated researcher

PubMed DOI Crossref

Relating fitness to long-term environmental variations in natura.

Milesi P, Lenormand T, Lagneau C, Weill M, Labbé P

Mol. Ecol. 25 (21) 5483-5499 [2016-11-00; online 2016-10-14]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Rapid Restoration of Vascularity and Oxygenation in Mouse and Human Islets Transplanted to Omentum May Contribute to Their Superior Function Compared to Intraportally Transplanted Islets.

Espes D, Lau J, Quach M, ..., Christoffersson G, Carlsson PO

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 16 (11) 3246-3254 [2016-11-00; online 2016-07-22]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Plasma proteomics in CML patients before and after initiation of tyrosine kinase inhibitor therapy reveals induced Th1 immunity and loss of angiogenic stimuli.

Söderlund S, Christiansson L, Persson I, ..., Olsson-Strömberg U, Loskog A

Leuk. Res. 50 (-) 95-103 [2016-11-00; online 2016-09-27]

Affiliated researcher

PubMed DOI Crossref

Migratory activation of parasitized dendritic cells by the protozoan Toxoplasma gondii 14-3-3 protein.

Weidner JM, Kanatani S, Uchtenhagen H, ..., Achour A, Barragan A

Cell. Microbiol. 18 (11) 1537-1550 [2016-11-00; online 2016-05-06]

Affiliated researcher

DOI Crossref

Methane oxidation at the water‐ice interface of an ice‐covered lake

Ricão Canelhas M, Denfeld BA, Weyhenmeyer GA, Bastviken D, Bertilsson S

Limnol. Oceanogr. 61 (S1) S78-S90 [2016-11-00; online 2016-03-29]

Affiliated researcher

PubMed DOI Crossref

Mass spectrometric analysis of synaptosomal membrane preparations for the determination of brain receptors, transporters and channels.

Sialana FJ, Gulyassy P, Májek P, ..., Bennett KL, Lubec G

Proteomics 16 (22) 2911-2920 [2016-11-00; online 2016-10-21]

Affiliated researcher

PubMed DOI Crossref

MID-PREGNANCY CORTICOTROPIN-RELEASING HORMONE LEVELS IN ASSOCIATION WITH POSTPARTUM DEPRESSIVE SYMPTOMS.

Iliadis SI, Sylvén S, Hellgren C, ..., Sundström Poromaa I, Skalkidou A

Depress Anxiety 33 (11) 1023-1030 [2016-11-00; online 2016-05-27]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Long-term outcome in young women with breast cancer: a population-based study.

Fredholm H, Magnusson K, Lindström LS, ..., Frisell J, Fredriksson I

Breast Cancer Res. Treat. 160 (1) 131-143 [2016-11-00; online 2016-09-13]

Affiliated researcher

PubMed DOI Crossref

Inferring Past Effective Population Size from Distributions of Coalescent Times.

Gattepaille L, Günther T, Jakobsson M

Genetics 204 (3) 1191-1206 [2016-11-00; online 2016-09-16]

Affiliated researcher

PubMed DOI Crossref

Identification of new heat-stable (STa) enterotoxin allele variants produced by human enterotoxigenic Escherichia coli (ETEC).

Joffré E, von Mentzer A, Svennerholm AM, Sjöling Å

Int J Med Microbiol 306 (7) 586-594 [2016-11-00; online 2016-06-15]

Astrid von Mentzer DDLS Fellow

PubMed DOI Crossref

High migration rates shape the postglacial history of amphi-Atlantic bryophytes.

Désamoré A, Patiño J, Mardulyn P, ..., Laenen B, Vanderpoorten A

Mol. Ecol. 25 (21) 5568-5584 [2016-11-00; online 2016-10-17]

Affiliated researcher

PubMed DOI Crossref

Heteroplasmy of mutant mitochondrial DNA A10398G and analysis of its prognostic value in non-small cell lung cancer.

Qi Y, Wei Y, Wang Q, ..., Gao Y, Zhou F

Oncol Lett 12 (5) 3081-3088 [2016-11-00; online 2016-09-05]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia.

Parker H, Rose-Zerilli MJ, Larrayoz M, ..., Oscier DG, Strefford JC

Leukemia 30 (11) 2179-2186 [2016-11-00; online 2016-05-20]

Affiliated researcher

PubMed DOI Crossref

Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia.

Teppo S, Laukkanen S, Liuksiala T, ..., Heinäniemi M, Lohi O

Genome Res. 26 (11) 1468-1477 [2016-11-00; online 2016-09-12]

Affiliated researcher

PubMed DOI Crossref

Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes.

Imgenberg-Kreuz J, Sandling JK, Almlöf JC, ..., Syvänen AC, Nordmark G

Ann. Rheum. Dis. 75 (11) 2029-2036 [2016-11-00; online 2016-02-08]

Affiliated researcher

PubMed DOI Crossref

Generation of human iPS cell line CTL07-II from human fibroblasts, under defined and xeno-free conditions.

Kele M, Day K, Rönnholm H, ..., Dahl N, Falk A

Stem Cell Res 17 (3) 474-478 [2016-11-00; online 2016-09-30]

Affiliated researcher

PubMed DOI Crossref

Fast and Accurate Protein False Discovery Rates on Large-Scale Proteomics Data Sets with Percolator 3.0.

The M, MacCoss MJ, Noble WS, Käll L

J. Am. Soc. Mass Spectrom. 27 (11) 1719-1727 [2016-11-00; online 2016-08-29]

Affiliated researcher

PubMed DOI Crossref

Extension of diffuse low-grade gliomas beyond radiological borders as shown by the coregistration of histopathological and magnetic resonance imaging data.

Zetterling M, Roodakker KR, Berntsson SG, ..., Larsson EM, Smits A

J. Neurosurg. 125 (5) 1155-1166 [2016-11-00; online 2016-02-26]

Affiliated researcher

PubMed DOI Crossref

Effects of cigarette smoking on cardiovascular-related protein profiles in two community-based cohort studies.

Huang B, Svensson P, Ärnlöv J, ..., Lind L, Ingelsson E

Atherosclerosis 254 (-) 52-58 [2016-11-00; online 2016-09-15]

Affiliated researcher

PubMed DOI Crossref

Diet adaptation in dog reflects spread of prehistoric agriculture.

Arendt M, Cairns KM, Ballard JW, Savolainen P, Axelsson E

Heredity (Edinb) 117 (5) 301-306 [2016-11-00; online 2016-07-13]

Affiliated researcher

PubMed DOI Crossref

Corrigendum to "Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs" [Nucl Med Biol 43 (2016) 397-402].

Rydén A, Nyman G, Nalin L, ..., Eriksson O, Jensen-Waern M

Nucl. Med. Biol. 43 (11) 742 [2016-11-00; online 2016-09-07]

Olof Eriksson SciLifeLab Fellow

DOI Crossref

Biodegradation mechanism of microcystin-LR by a novel isolate of Rhizobium sp. TH and the evolutionary origin of the mlrA gene

Zhu X, Shen Y, Chen X, ..., Tao J, Ling Y

International Biodeterioration & Biodegradation 115 (-) 17-25 [2016-11-00; online 2016-11-00]

Affiliated researcher

PubMed DOI Crossref

Bacillus wiedmannii sp. nov., a psychrotolerant and cytotoxic Bacillus cereus group species isolated from dairy foods and dairy environments.

Miller RA, Beno SM, Kent DJ, ..., Boor KJ, Kovac J

Int. J. Syst. Evol. Microbiol. 66 (11) 4744-4753 [2016-11-00; online 2016-08-12]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Amy2B copy number variation reveals starch diet adaptations in ancient European dogs.

Ollivier M, Tresset A, Bastian F, ..., Hitte C, Hänni C

R Soc Open Sci 3 (11) 160449 [2016-11-00; online 2016-11-09]

Affiliated researcher

PubMed DOI Crossref

ARAP2 promotes GLUT1-mediated basal glucose uptake through regulation of sphingolipid metabolism.

Chaudhari A, Håversen L, Mobini R, ..., Perkins R, Borén J

Biochim. Biophys. Acta 1861 (11) 1643-1651 [2016-11-00; online 2016-07-27]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Rawcopy: Improved copy number analysis with Affymetrix arrays.

Mayrhofer M, Viklund B, Isaksson A

Sci Rep 6 (-) 36158 [2016-10-31; online 2016-10-31]

Affiliated researcher

PubMed DOI Crossref

Evolution of heterogeneous genome differentiation across multiple contact zones in a crow species complex.

Vijay N, Bossu CM, Poelstra JW, ..., Kryukov AP, Wolf JB

Nat Commun 7 (-) 13195 [2016-10-31; online 2016-10-31]

Affiliated researcher

PubMed DOI Crossref

Measurement of serum C-reactive protein concentration for discriminating between suppurative arthritis and osteoarthritis in dogs.

Hillström A, Bylin J, Hagman R, ..., Fall T, Kjelgaard-Hansen M

BMC Vet. Res. 12 (1) 240 [2016-10-28; online 2016-10-28]

Affiliated researcher

PubMed DOI Crossref

Thermodynamics of Nanobody Binding to Lactose Permease.

Hariharan P, Andersson M, Jiang X, ..., Kaback HR, Guan L

Biochemistry 55 (42) 5917-5926 [2016-10-25; online 2016-10-12]

Affiliated researcher

PubMed DOI Crossref

Mesenchymal state of intimal cells may explain higher propensity to ascending aortic aneurysm in bicuspid aortic valves.

Maleki S, Kjellqvist S, Paloschi V, ..., Eriksson P, Björck HM

Sci Rep 6 (-) 35712 [2016-10-25; online 2016-10-25]

Affiliated researcher

PubMed DOI Crossref

Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine.

Nys M, Wijckmans E, Farinha A, ..., Lindahl E, Ulens C

Proc. Natl. Acad. Sci. U.S.A. 113 (43) E6696-E6703 [2016-10-25; online 2016-10-10]

Affiliated researcher

PubMed DOI Crossref

Identification of mutations, gene expression changes and fusion transcripts by whole transcriptome RNAseq in docetaxel resistant prostate cancer cells.

Ma Y, Miao Y, Peng Z, ..., Nilsson S, Li C

Springerplus 5 (1) 1861 [2016-10-24; online 2016-10-24]

Affiliated researcher

PubMed DOI Crossref

Evaluation of Generalized Born Models for Large Scale Affinity Prediction of Cyclodextrin Host-Guest Complexes.

Zhang H, Yin C, Yan H, van der Spoel D

J Chem Inf Model 56 (10) 2080-2092 [2016-10-24; online 2016-10-04]

Affiliated researcher

PubMed DOI Crossref

Cytokine profiling of tumor interstitial fluid of the breast and its relationship with lymphocyte infiltration and clinicopathological characteristics.

Espinoza JA, Jabeen S, Batra R, ..., Kristensen VN, Gromova I

Oncoimmunology 5 (12) e1248015 [2016-10-24; online 2016-10-24]

Affiliated researcher

PubMed DOI Crossref

Structure-Based Screening of Uncharted Chemical Space for Atypical Adenosine Receptor Agonists.

Rodríguez D, Chakraborty S, Warnick E, ..., Jacobson KA, Carlsson J

ACS chemical biology 11 (10) 2763-2772 [2016-10-21; online 2016-08-22]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Integrative analysis of human omics data using biomolecular networks.

Robinson JL, Nielsen J

Mol Biosyst 12 (10) 2953-2964 [2016-10-20; online 2016-08-11]

Affiliated researcher

PubMed DOI Crossref

Gene-specific correlation of RNA and protein levels in human cells and tissues.

Edfors F, Danielsson F, Hallström BM, ..., Forsström B, Uhlén M

Mol Syst Biol 12 (10) 883 [2016-10-20; online 2016-10-20]

Affiliated researcher

PubMed DOI Crossref

Two-Step Mechanism of Cellular Uptake of Cationic Gold Nanoparticles Modified by (16-Mercaptohexadecyl)trimethylammonium Bromide.

Zarska M, Novotny F, Havel F, ..., Proska J, Hodny Z

Bioconjug. Chem. 27 (10) 2558-2574 [2016-10-19; online 2016-09-26]

Affiliated researcher

PubMed DOI Crossref

Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures.

Diwakarla S, Nylander E, Grönbladh A, ..., Chai SY, Hallberg M

ACS Chem Neurosci 7 (10) 1383-1392 [2016-10-19; online 2016-08-08]

Affiliated researcher

PubMed DOI Crossref

Increased Levels of Extracellular Microvesicle Markers and Decreased Levels of Endocytic/Exocytic Proteins in the Alzheimer's Disease Brain.

Musunuri S, Khoonsari PE, Mikus M, ..., Nilsson P, Kultima K

J. Alzheimers Dis. 54 (4) 1671-1686 [2016-10-18; online 2016-10-22]

Affiliated researcher

PubMed DOI Crossref

FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.

Suryo Rahmanto A, Savov V, Brunner A, ..., Swartling FJ, Sangfelt O

EMBO J. 35 (20) 2192-2212 [2016-10-17; online 2016-09-13]

Affiliated researcher

PubMed DOI Crossref

Binding of Pollutants to Biomolecules: A Simulation Study.

Yildirim A, Zhang J, Manzetti S, van der Spoel D

Chem. Res. Toxicol. 29 (10) 1679-1688 [2016-10-17; online 2016-09-13]

Affiliated researcher

PubMed DOI Crossref

Reconstructing a hydrogen-driven microbial metabolic network in Opalinus Clay rock.

Bagnoud A, Chourey K, Hettich RL, ..., Schwyn B, Bernier-Latmani R

Nat Commun 7 (-) 12770 [2016-10-14; online 2016-10-14]

Affiliated researcher

PubMed DOI Crossref

Massive and parallel expression profiling using microarrayed single-cell sequencing.

Vickovic S, Ståhl PL, Salmén F, ..., Frisén J, Lundeberg J

Nat Commun 7 (1) 13182 [2016-10-14; online 2016-10-14]

Affiliated researcher Magda Bienko Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis.

Loley C, Alver M, Assimes TL, ..., Erdmann J, König IR

Sci Rep 6 (-) 35278 [2016-10-12; online 2016-10-12]

Affiliated researcher

PubMed DOI Crossref

Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.

Segerstolpe Å, Palasantza A, Eliasson P, ..., Ämmälä C, Sandberg R

Cell Metab. 24 (4) 593-607 [2016-10-11; online 2016-09-22]

Affiliated researcher

PubMed DOI Crossref

Hydrophobic Clusters Raise the Threshold Hydrophilicity for Insertion of Transmembrane Sequences in Vivo.

Stone TA, Schiller N, Workewych N, von Heijne G, Deber CM

Biochemistry 55 (40) 5772-5779 [2016-10-11; online 2016-09-29]

Affiliated researcher

PubMed DOI Crossref

The structure and diversity of human, animal and environmental resistomes.

Pal C, Bengtsson-Palme J, Kristiansson E, Larsson DG

Microbiome 4 (1) 54 [2016-10-07; online 2016-10-07]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Multidimensional Normalization to Minimize Plate Effects of Suspension Bead Array Data.

Hong MG, Lee W, Nilsson P, Pawitan Y, Schwenk JM

J. Proteome Res. 15 (10) 3473-3480 [2016-10-07; online 2016-09-12]

Affiliated researcher

PubMed DOI Crossref

Picodroplet partitioned whole genome amplification of low biomass samples preserves genomic diversity for metagenomic analysis.

Hammond M, Homa F, Andersson-Svahn H, Ettema TJ, Joensson HN

Microbiome 4 (1) 52 [2016-10-06; online 2016-10-06]

Affiliated researcher

PubMed DOI Crossref

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells.

La Manno G, Gyllborg D, Codeluppi S, ..., Arenas E, Linnarsson S

Cell 167 (2) 566-580.e19 [2016-10-06; online 2016-10-08]

Affiliated researcher

PubMed DOI Crossref

Systems Toxicology: Systematic Approach to Predict Toxicity.

Kiani NA, Shang MM, Tegner J

Curr. Pharm. Des. 22 (46) 6911-6917 [2016-10-05; online 2016-10-05]

Affiliated researcher

PubMed DOI Crossref

Nematodes join the family of chondroitin sulfate-synthesizing organisms: Identification of an active chondroitin sulfotransferase in Caenorhabditis elegans.

Dierker T, Shao C, Haitina T, ..., Hinas A, Kjellén L

Sci Rep 6 (-) 34662 [2016-10-05; online 2016-10-05]

Affiliated researcher

PubMed DOI Crossref

ProQ3: Improved model quality assessments using Rosetta energy terms.

Uziela K, Shu N, Wallner B, Elofsson A

Sci Rep 6 (-) 33509 [2016-10-04; online 2016-10-04]

Affiliated researcher

PubMed DOI Crossref

Sensitizing ovarian cancer cells to chemotherapy by interfering with pathways that are involved in the formation of cancer stem cells.

Saydaminova K, Strauss R, Xie M, ..., Ding S, Lieber A

Cancer Biol. Ther. 17 (10) 1079-1088 [2016-10-02; online 2016-08-30]

Affiliated researcher

PubMed DOI Crossref

The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation.

Jouhilahti EM, Madissoon E, Vesterlund L, ..., Katayama S, Kere J

Development 143 (19) 3459-3469 [2016-10-01; online 2016-08-30]

Affiliated researcher

PubMed DOI Crossref

MultiQC: summarize analysis results for multiple tools and samples in a single report.

Ewels P, Magnusson M, Lundin S, Käller M

Bioinformatics 32 (19) 3047-3048 [2016-10-01; online 2016-06-16]

Affiliated researcher

PubMed DOI Crossref

Association of Adipose Tissue Fatty Acids With Cardiovascular and All-Cause Mortality in Elderly Men.

Iggman D, Ärnlöv J, Cederholm T, Risérus U

JAMA Cardiol 1 (7) 745-753 [2016-10-01; online 2016-10-21]

Affiliated researcher

PubMed DOI Crossref

Whole-Exome Sequencing Suggests LAMB3 as a Susceptibility Gene for Morbid Obesity.

Jiao H, Kulyté A, Näslund E, ..., Arner P, Dahlman I

Diabetes 65 (10) 2980-2989 [2016-10-00; online 2016-07-18]

Affiliated researcher

PubMed DOI Crossref

Ultra-High-Throughput Sample Preparation System for Lymphocyte Immunophenotyping Point-of-Care Diagnostics.

Walsh DI, Murthy SK, Russom A

J Lab Autom 21 (5) 706-712 [2016-10-00; online 2016-02-26]

Affiliated researcher

PubMed DOI Crossref

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

Surendran P, Drenos F, Young R, ..., Howson JM, Munroe PB

Nat. Genet. 48 (10) 1151-1161 [2016-10-00; online 2016-09-12]

Affiliated researcher

PubMed DOI Crossref

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.

Ehret GB, Ferreira T, Chasman DI, ..., Newton-Cheh C, Munroe PB

Nat. Genet. 48 (10) 1171-1184 [2016-10-00; online 2016-09-12]

Affiliated researcher

PubMed DOI Crossref

The Tyrosine Kinase Inhibitor Imatinib Augments Extracellular Fluid Exchange and Reduces Average Collagen Fibril Diameter in Experimental Carcinoma.

Olsson PO, Gustafsson R, In 't Zandt R, ..., Rubin K, Kalamajski S

Mol. Cancer Ther. 15 (10) 2455-2464 [2016-10-00; online 2016-07-29]

Affiliated researcher

PubMed DOI Crossref

Soluble CD93 Is Involved in Metabolic Dysregulation but Does Not Influence Carotid Intima-Media Thickness.

Strawbridge RJ, Hilding A, Silveira A, ..., Bäcklund A, IMPROVE Study Group

Diabetes 65 (10) 2888-2899 [2016-10-00; online 2016-09-24]

Affiliated researcher

PubMed DOI Crossref

Rationale and design of the PREFERS (Preserved and Reduced Ejection Fraction Epidemiological Regional Study) Stockholm heart failure study: an epidemiological regional study in Stockholm county of 2.1 million inhabitants.

Linde C, Eriksson MJ, Hage C, ..., Persson H, Stockholm County/Karolinska Institutet 4D heart failure investigators

Eur. J. Heart Fail. 18 (10) 1287-1297 [2016-10-00; online 2016-07-07]

Affiliated researcher

PubMed DOI Crossref

Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors.

Fotouhi O, Kjellin H, Larsson C, ..., Lehtiö J, Kjellman M

J. Clin. Endocrinol. Metab. 101 (10) 3616-3627 [2016-10-00; online 2016-07-26]

Affiliated researcher

PubMed DOI Crossref

Open for collaboration: an academic platform for drug discovery and development at SciLifeLab.

Arvidsson PI, Sandberg K, Forsberg-Nilsson K

Drug Discov. Today 21 (10) 1690-1698 [2016-10-00; online 2016-06-29]

Affiliated researcher

PubMed DOI Crossref

Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes.

Fall T, Salihovic S, Brandmaier S, ..., Ingelsson E, Lind L

Diabetologia 59 (10) 2114-2124 [2016-10-00; online 2016-07-12]

Affiliated researcher

PubMed DOI Crossref

New insights into the history of domesticated and wild apricots and its contribution to Plum pox virus resistance.

Decroocq S, Cornille A, Tricon D, ..., Giraud T, Decroocq V

Mol. Ecol. 25 (19) 4712-4729 [2016-10-00; online 2016-09-06]

Affiliated researcher

PubMed DOI Crossref

Mutations in HECW2 are associated with intellectual disability and epilepsy.

Halvardson J, Zhao JJ, Zaghlool A, ..., Thuresson AC, Feuk L

J. Med. Genet. 53 (10) 697-704 [2016-10-00; online 2016-06-22]

Affiliated researcher

PubMed DOI Crossref

Multiplexed next-generation sequencing and de novo assembly to obtain near full-length HIV-1 genome from plasma virus.

Aralaguppe SG, Siddik AB, Manickam A, ..., Sonnerborg A, Neogi U

J. Virol. Methods 236 (-) 98-104 [2016-10-00; online 2016-07-19]

Affiliated researcher

PubMed DOI Crossref

Metabolomic Quality Assessment of EDTA Plasma and Serum Samples.

Malm L, Tybring G, Moritz T, Landin B, Galli J

Biopreserv Biobank 14 (5) 416-423 [2016-10-00; online 2016-06-27]

Affiliated researcher

PubMed DOI Crossref

Mechanisms and regulation of endothelial VEGF receptor signalling.

Simons M, Gordon E, Claesson-Welsh L

Nat. Rev. Mol. Cell Biol. 17 (10) 611-625 [2016-10-00; online 2016-07-27]

Affiliated researcher

PubMed DOI Crossref

Influence of APOE Gene Polymorphism on Interindividual and Interethnic Warfarin Dosage Requirement: A Systematic Review and Meta-Analysis.

Yu WY, Sun X, Wadelius M, ..., Ma WL, Yang GP

Cardiovasc Ther 34 (5) 297-307 [2016-10-00; online 2016-04-12]

Affiliated researcher

PubMed DOI Crossref

Identification of autoimmune polyendocrine syndrome type 1 in patients with isolated hypoparathyroidism.

Sahoo SK, Zaidi G, Srivastava R, ..., Aggarwal R, Bhatia E

Clin. Endocrinol. (Oxf) 85 (4) 544-550 [2016-10-00; online 2016-06-28]

Affiliated researcher

PubMed DOI Crossref

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci.

Walford GA, Gustafsson S, Rybin D, ..., Ingelsson E, Florez JC

Diabetes 65 (10) 3200-3211 [2016-10-00; online 2016-07-14]

Affiliated researcher

PubMed DOI Crossref

Generation and analyses of human synthetic antibody libraries and their application for protein microarrays.

Säll A, Walle M, Wingren C, ..., Borrebaeck CAK, Persson H

Protein Eng. Des. Sel. 29 (10) 427-437 [2016-10-00; online 2016-09-01]

Affiliated researcher

PubMed DOI Crossref

Functional Metabolomics Describes the Yeast Biosynthetic Regulome

Mülleder M, Calvani E, Alam MT, ..., Zelezniak A, Ralser M

Cell 167 (2) 553-565.e12 [2016-10-00; online 2016-10-00]

Aleksej Zelezniak SciLifeLab Fellow

PubMed DOI Crossref

Elevated Basal Insulin Secretion in Type 2 Diabetes Caused by Reduced Plasma Membrane Cholesterol.

Nagaraj V, Kazim AS, Helgeson J, ..., Zhang E, Renström E

Mol. Endocrinol. 30 (10) 1059-1069 [2016-10-00; online 2016-08-17]

Affiliated researcher

PubMed DOI Crossref

Effects of multiple dimensions of bacterial diversity on functioning, stability and multifunctionality.

Roger F, Bertilsson S, Langenheder S, Osman OA, Gamfeldt L

Ecology 97 (10) 2716-2728 [2016-10-00; online 2016-09-15]

Affiliated researcher

PubMed DOI Crossref

Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study.

Nowak C, Salihovic S, Ganna A, ..., Ingelsson E, Fall T

PLoS Genet 12 (10) e1006379 [2016-10-00; online 2016-10-21]

Affiliated researcher

PubMed DOI Crossref

DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands.

Wahlberg P, Lundmark A, Nordlund J, ..., Lönnerholm G, Syvänen AC

Epigenomics 8 (10) 1367-1387 [2016-10-00; online 2016-08-23]

Affiliated researcher

PubMed DOI Crossref

Cystatin C-based glomerular filtration rate associates more closely with mortality than creatinine-based or combined glomerular filtration rate equations in unselected patients.

Helmersson-Karlqvist J, Ärnlöv J, Larsson A

Eur J Prev Cardiol 23 (15) 1649-1657 [2016-10-00; online 2016-04-01]

Affiliated researcher

PubMed DOI Crossref

Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden.

Verhoef TI, Redekop WK, Langenskiold S, ..., Hughes DA, Pirmohamed M

Pharmacogenomics J. 16 (5) 478-484 [2016-10-00; online 2016-06-07]

Affiliated researcher

PubMed DOI Crossref

Connectivity to the surface determines diversity patterns in subsurface aquifers of the Fennoscandian shield.

Hubalek V, Wu X, Eiler A, ..., Bertilsson S, Ionescu D

ISME J 10 (10) 2447-2458 [2016-10-00; online 2016-03-29]

Affiliated researcher

PubMed DOI Crossref

Circulating levels of perfluoroalkyl substances are associated with dietary patterns - A cross sectional study in elderly Swedish men and women.

Sjogren P, Montse R, Lampa E, ..., Lind L, Lind PM

Environ. Res. 150 (-) 59-65 [2016-10-00; online 2016-05-27]

Affiliated researcher

PubMed DOI Crossref

Changes in serum levels of perfluoroalkyl substances during a 10-year follow-up period in a large population-based cohort.

Stubleski J, Salihovic S, Lind L, ..., van Bavel B, Kärrman A

Environ Int 95 (-) 86-92 [2016-10-00; online 2016-08-16]

Affiliated researcher

PubMed DOI Crossref

Cause and consequences of the activated type I interferon system in SLE.

Eloranta ML, Rönnblom L

J. Mol. Med. 94 (10) 1103-1110 [2016-10-00; online 2016-04-20]

Affiliated researcher

PubMed DOI Crossref

Biophysics in drug discovery: impact, challenges and opportunities.

Renaud JP, Chung CW, Danielson UH, ..., Hubbard RE, Nar H

Nat Rev Drug Discov 15 (10) 679-698 [2016-10-00; online 2016-08-12]

Affiliated researcher

PubMed DOI Crossref

Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis.

Landegren N, Pourmousa Lindberg M, Skov J, ..., Fenton RA, Kämpe O

J. Am. Soc. Nephrol. 27 (10) 3220-3228 [2016-10-00; online 2016-03-16]

Affiliated researcher

PubMed DOI Crossref

Associations between the FKBP5 haplotype, exposure to violence and anxiety in females.

Isaksson J, Comasco E, Åslund C, ..., Andershed H, Nilsson KW

Psychoneuroendocrinology 72 (-) 196-204 [2016-10-00; online 2016-07-15]

Erika Comasco SciLifeLab Fellow

DOI Crossref

An introduction to plant phylogenomics with a focus on palms

Barrett CF, Bacon CD, Antonelli A, Cano Á, Hofmann T

Bot. J. Linn. Soc. 182 (2) 234-255 [2016-10-00; online 2016-03-18]

DDLS Fellow Tobias Andermann

PubMed DOI Crossref

A proposal for validation of antibodies.

Uhlen M, Bandrowski A, Carr S, ..., Snyder M, Yamamoto T

Nat. Methods 13 (10) 823-827 [2016-10-00; online 2016-09-05]

Affiliated researcher

PubMed DOI Crossref

Gemcitabine reduces MDSCs, tregs and TGFβ-1 while restoring the teff/treg ratio in patients with pancreatic cancer.

Eriksson E, Wenthe J, Irenaeus S, Loskog A, Ullenhag G

J Transl Med 14 (1) 282 [2016-09-29; online 2016-09-29]

Affiliated researcher

PubMed DOI Crossref

Detecting individual extracellular vesicles using a multicolor in situ proximity ligation assay with flow cytometric readout.

Löf L, Ebai T, Dubois L, ..., Landegren U, Kamali-Moghaddam M

Sci Rep 6 (-) 34358 [2016-09-29; online 2016-09-29]

Affiliated researcher

PubMed DOI Crossref

Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.

Butler LM, Hallström BM, Fagerberg L, ..., Renné T, Odeberg J

Cell Systems 3 (3) 287-301.e3 [2016-09-28; online 2016-09-15]

Affiliated researcher

PubMed DOI Crossref

Transforming growth factor β as regulator of cancer stemness and metastasis.

Bellomo C, Caja L, Moustakas A

Br. J. Cancer 115 (7) 761-769 [2016-09-27; online 2016-08-18]

Affiliated researcher

PubMed DOI Crossref

Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes.

Lindqvist CM, Lundmark A, Nordlund J, ..., Berglund EC, Syvänen AC

Oncotarget 7 (39) 64071-64088 [2016-09-27; online 2016-09-04]

Affiliated researcher

PubMed DOI Crossref

Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity.

Petros Z, Lee MM, Takahashi A, ..., Kubo M, Aklillu E

BMC Genomics 17 (1) 755 [2016-09-26; online 2016-09-26]

Affiliated researcher

DOI Crossref

Annotating public fungal ITS sequences from the built environment according to the MIxS-Built Environment standard – a report from a May 23-24, 2016 workshop (Gothenburg, Sweden)

Abarenkov K, Adams RI, Laszlo I, ..., Schriml L, Nilsson RH

MykoKeys 16 (-) 1-15 [2016-09-26; online 2016-09-26]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Exploration of high-density protein microarrays for antibody validation and autoimmunity profiling.

Sjöberg R, Mattsson C, Andersson E, ..., Ayoglu B, Nilsson P

N Biotechnol 33 (5 Pt A) 582-592 [2016-09-25; online 2015-09-28]

Affiliated researcher

PubMed DOI Crossref

Advancing the global proteome survey platform by using an oriented single chain antibody fragment immobilization approach.

Säll A, Persson H, Ohlin M, Borrebaeck CA, Wingren C

N Biotechnol 33 (5 Pt A) 503-513 [2016-09-25; online 2015-12-15]

Affiliated researcher

PubMed DOI Crossref

"Smart" drug loaded nanoparticle delivery from a self-healing hydrogel enabled by dynamic magnesium-biopolymer chemistry.

Shi L, Han Y, Hilborn J, Ossipov D

Chem. Commun. (Camb.) 52 (74) 11151-11154 [2016-09-25; online 2016-08-23]

Affiliated researcher

PubMed DOI Crossref

Overlap in serum metabolic profiles between non-related diseases: Implications for LC-MS metabolomics biomarker discovery.

Lindahl A, Forshed J, Nordström A

Biochem. Biophys. Res. Commun. 478 (3) 1472-1477 [2016-09-23; online 2016-08-28]

Affiliated researcher

PubMed DOI Crossref

A global genetic interaction network maps a wiring diagram of cellular function.

Costanzo M, VanderSluis B, Koch EN, ..., Andrews B, Boone C

Science (New York, N.Y.) 353 (6306) aaf1420-aaf1420 [2016-09-23; online 2016-10-07]

Affiliated researcher SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

The Oncolytic Efficacy and in Vivo Pharmacokinetics of [2-(4-Chlorophenyl)quinolin-4-yl](piperidine-2-yl)methanol (Vacquinol-1) Are Governed by Distinct Stereochemical Features.

Hammarström LG, Harmel RK, Granath M, ..., Lehmann F, Ernfors P

J. Med. Chem. 59 (18) 8577-8592 [2016-09-22; online 2016-09-08]

Affiliated researcher

PubMed DOI Crossref

RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma.

Sakurai T, Isogaya K, Sakai S, ..., Miyazono K, Koinuma D

Oncogene 35 (38) 5000-5009 [2016-09-22; online 2016-02-29]

Affiliated researcher

PubMed DOI Crossref

NETosis in Cancer - Platelet-Neutrophil Crosstalk Promotes Tumor-Associated Pathology.

Olsson AK, Cedervall J

Front Immunol 7 (-) 373 [2016-09-21; online 2016-09-21]

Affiliated researcher

DOI Crossref

Large-scale calculations of gas phase thermochemistry: Enthalpy of formation, standard entropy, and heat capacity

Ghahremanpour MM, van Maaren PJ, Ditz JC, Lindh R, van der Spoel D

The Journal of Chemical Physics 145 (11) 114305 [2016-09-21; online 2016-09-21]

Affiliated researcher

PubMed DOI Crossref

WD40 domain of Apc1 is critical for the coactivator-induced allosteric transition that stimulates APC/C catalytic activity.

Li Q, Chang L, Aibara S, ..., Zhang Z, Barford D

Proc. Natl. Acad. Sci. U.S.A. 113 (38) 10547-10552 [2016-09-20; online 2016-09-06]

Affiliated researcher

PubMed DOI Crossref

The Number of Stenotic Intracranial Arteries Is Independently Associated with Ischemic Stroke Severity.

Wei X, Liu Z, Li M, ..., Wang B, Mi J

PLoS ONE 11 (9) e0163356 [2016-09-20; online 2016-09-20]

Affiliated researcher

PubMed DOI Crossref

Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with β-Arylpropyl Analogues of Fosmidomycin.

Sooriyaarachchi S, Chofor R, Risseeuw MD, ..., Van Calenbergh S, Mowbray SL

ChemMedChem 11 (18) 2024-2036 [2016-09-20; online 2016-08-03]

Affiliated researcher

PubMed DOI Crossref

Pharmacokinetic considerations of nanodelivery to the brain: Using modeling and simulations to predict the outcome of liposomal formulations.

Lindqvist A, Fridén M, Hammarlund-Udenaes M

Eur J Pharm Sci 92 (-) 173-182 [2016-09-20; online 2016-07-05]

Affiliated researcher

PubMed DOI Crossref

Energetics of side-chain snorkeling in transmembrane helices probed by nonproteinogenic amino acids.

Öjemalm K, Higuchi T, Lara P, ..., Suga H, von Heijne G

Proc. Natl. Acad. Sci. U.S.A. 113 (38) 10559-10564 [2016-09-20; online 2016-09-06]

Affiliated researcher

PubMed DOI Crossref

Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction.

Genshaft AS, Li S, Gallant CJ, ..., Landegren U, Shalek AK

Genome Biol. 17 (1) 188 [2016-09-19; online 2016-09-19]

Affiliated researcher

PubMed DOI Crossref

Functional and Structural Consequences of Nine

de Paula Michelatto D, Karlsson L, Lusa AL, ..., de Mello MP, Lajic S

Int J Endocrinol 2016 (-) 4209670 [2016-09-19; online 2016-09-19]

Affiliated researcher

PubMed DOI Crossref

Investigation of rare and low-frequency variants using high-throughput sequencing with pooled DNA samples.

Wang J, Skoog T, Einarsdottir E, ..., Kere J, Jiao H

Sci Rep 6 (-) 33256 [2016-09-16; online 2016-09-16]

Affiliated researcher

PubMed DOI Crossref

XMetDB: an open access database for xenobiotic metabolism.

Spjuth O, Rydberg P, Willighagen EL, Evelo CT, Jeliazkova N

J Cheminform 8 (-) 47 [2016-09-15; online 2016-09-15]

Affiliated researcher

PubMed DOI Crossref

Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions.

Wiśniewski JR, Wegler C, Artursson P

Anal. Biochem. 509 (-) 82-88 [2016-09-15; online 2016-06-14]

Affiliated researcher

PubMed DOI Crossref

NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine.

Valerie NC, Hagenkort A, Page BD, ..., Jemth AS, Helleday T

Cancer Res. 76 (18) 5501-5511 [2016-09-15; online 2016-08-16]

Affiliated researcher

PubMed DOI Crossref

Life history of the stem tetrapod Acanthostega revealed by synchrotron microtomography.

Sanchez S, Tafforeau P, Clack JA, Ahlberg PE

Nature 537 (7620) 408-411 [2016-09-15; online 2016-09-07]

Affiliated researcher

PubMed DOI Crossref

IL-15 activates mTOR and primes stress-activated gene expression leading to prolonged antitumor capacity of NK cells.

Mao Y, van Hoef V, Zhang X, ..., Kiessling R, Lundqvist A

Blood 128 (11) 1475-1489 [2016-09-15; online 2016-07-27]

Affiliated researcher SciLifeLab Fellow Yumeng Mao

PubMed DOI Crossref

Analysis with the exome array identifies multiple new independent variants in lipid loci.

Kanoni S, Masca NG, Stirrups KE, ..., Samani NJ, Deloukas P

Hum. Mol. Genet. 25 (18) 4094-4106 [2016-09-15; online 2016-07-27]

Affiliated researcher

PubMed DOI Crossref

Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.

Morgado-Palacin I, Day A, Murga M, ..., Nussenzweig A, Fernandez-Capetillo O

Sci Signal 9 (445) ra91 [2016-09-13; online 2016-09-13]

Affiliated researcher

PubMed DOI Crossref

Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cells.

Morin A, Kwan T, Ge B, ..., Lathrop MG, Pastinen T

BMC Med Genomics 9 (1) 59 [2016-09-13; online 2016-09-13]

Affiliated researcher

PubMed DOI Crossref

Efficacy of ATR inhibitors as single agents in Ewing sarcoma.

Nieto-Soler M, Morgado-Palacin I, Lafarga V, ..., Nussenzweig A, Fernandez-Capetillo O

Oncotarget 7 (37) 58759-58767 [2016-09-13; online 2016-09-01]

Affiliated researcher

PubMed DOI Crossref

Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing.

Ferreira PG, Oti M, Barann M, ..., Guigó R, Sammeth M

Sci Rep 6 (1) 32406 [2016-09-12; online 2016-09-12]

Affiliated researcher Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Efficient Integration of Coupled Electrical-Chemical Systems in Multiscale Neuronal Simulations.

Brocke E, Bhalla US, Djurfeldt M, Hellgren Kotaleski J, Hanke M

Front Comput Neurosci 10 (-) 97 [2016-09-12; online 2016-09-12]

Affiliated researcher

DOI Crossref

The helical structure of DNA facilitates binding

Berg OG, Mahmutovic A, Marklund E, Elf J

J. Phys. A: Math. Theor. 49 (36) 364002 [2016-09-09; online 2016-08-16]

Affiliated researcher Emil Marklund SciLifeLab Fellow

PubMed DOI Crossref

Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade.

Eissler N, Mao Y, Brodin D, ..., Kiessling R, Kogner P

Oncoimmunology 5 (12) e1232222 [2016-09-09; online 2016-09-09]

Affiliated researcher SciLifeLab Fellow Yumeng Mao

PubMed DOI Crossref

Enhancing Endosomal Escape for Intracellular Delivery of Macromolecular Biologic Therapeutics.

Lönn P, Kacsinta AD, Cui XS, ..., Gogoi K, Dowdy SF

Sci Rep 6 (-) 32301 [2016-09-08; online 2016-09-08]

Affiliated researcher

PubMed DOI Crossref

NDST2 (N-Deacetylase/N-Sulfotransferase-2) Enzyme Regulates Heparan Sulfate Chain Length.

Deligny A, Dierker T, Dagälv A, ..., Merry CLR, Kjellén L

J. Biol. Chem. 291 (36) 18600-18607 [2016-09-02; online 2016-07-07]

Affiliated researcher

PubMed DOI Crossref

Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity.

Mahajan A, Rodan AR, Le TH, ..., Morris AP, Franceschini N

Am. J. Hum. Genet. 99 (3) 636-646 [2016-09-01; online 2016-09-03]

Affiliated researcher

PubMed DOI Crossref

The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation.

Schulte T, Mikaelsson C, Beaussart A, ..., Nygren PÅ, Achour A

Sci Rep 6 (-) 32371 [2016-09-01; online 2016-09-01]

Affiliated researcher

PubMed DOI Crossref

PRED-TMBB2: improved topology prediction and detection of beta-barrel outer membrane proteins.

Tsirigos KD, Elofsson A, Bagos PG

Bioinformatics 32 (17) i665-i671 [2016-09-01; online 2016-09-03]

Affiliated researcher

PubMed DOI Crossref

POLD3 Is Haploinsufficient for DNA Replication in Mice.

Murga M, Lecona E, Kamileri I, ..., Halazonetis TD, Fernandez-Capetillo O

Mol. Cell 63 (5) 877-883 [2016-09-01; online 2016-08-11]

Affiliated researcher

PubMed DOI Crossref

Drug response prediction by inferring pathway-response associations with kernelized Bayesian matrix factorization.

Ammad-Ud-Din M, Khan SA, Malani D, ..., Aittokallio T, Kaski S

Bioinformatics 32 (17) i455-i463 [2016-09-01; online 2016-09-03]

Affiliated researcher

PubMed DOI Crossref

Benchmarking the next generation of homology inference tools.

Saripella GV, Sonnhammer EL, Forslund K

Bioinformatics 32 (17) 2636-2641 [2016-09-01; online 2016-06-01]

Affiliated researcher

PubMed DOI Crossref

Absence of the Autophagy Adaptor SQSTM1/p62 Causes Childhood-Onset Neurodegeneration with Ataxia, Dystonia, and Gaze Palsy.

Haack TB, Ignatius E, Calvo-Garrido J, ..., Carroll CJ, Klopstock T

Am. J. Hum. Genet. 99 (3) 735-743 [2016-09-01; online 2016-08-18]

Affiliated researcher

PubMed DOI Crossref

A novel variant in MYLK causes thoracic aortic dissections: genotypic and phenotypic description.

Hannuksela M, Stattin EL, Klar J, ..., Sörensen K, Carlberg B

BMC Med. Genet. 17 (1) 61 [2016-09-01; online 2016-09-01]

Affiliated researcher

PubMed DOI Crossref

Use of BODIPY-Cholesterol (TF-Chol) for Visualizing Lysosomal Cholesterol Accumulation.

Hölttä-Vuori M, Sezgin E, Eggeling C, Ikonen E

Traffic 17 (9) 1054-1057 [2016-09-00; online 2016-06-13]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Tissue microarray profiling in human heart failure.

Lal S, Nguyen L, Tezone R, ..., Li A, Dos Remedios C

Proteomics 16 (17) 2319-2326 [2016-09-00; online 2016-08-11]

Affiliated researcher

PubMed DOI Crossref

The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity.

Sandalova T, Lee M, Henriques-Normark B, ..., Mellroth P, Achour A

Mol. Microbiol. 101 (6) 954-967 [2016-09-00; online 2016-07-05]

Affiliated researcher

PubMed DOI Crossref

The Sac3 TPR-like region in the Saccharomyces cerevisiae TREX-2 complex is more extensive but independent of the CID region.

Aibara S, Bai XC, Stewart M

J. Struct. Biol. 195 (3) 316-324 [2016-09-00; online 2016-07-12]

Affiliated researcher

PubMed DOI Crossref

The Impact of Endurance Training on Human Skeletal Muscle Memory, Global Isoform Expression and Novel Transcripts.

Lindholm ME, Giacomello S, Werne Solnestam B, ..., Kjellqvist S, Sundberg CJ

PLoS Genet 12 (9) e1006294 [2016-09-00; online 2016-09-22]

Affiliated researcher

PubMed DOI Crossref

Strategies to improve usability and preserve accuracy in biological sequence databases.

Bengtsson-Palme J, Boulund F, Edström R, ..., Sanli K, Thorell K

Proteomics 16 (18) 2454-2460 [2016-09-00; online 2016-08-17]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Role of DARPP-32 and ARPP-21 in the Emergence of Temporal Constraints on Striatal Calcium and Dopamine Integration.

Nair AG, Bhalla US, Hellgren Kotaleski J

PLoS Comput Biol 12 (9) e1005080 [2016-09-00; online 2016-09-01]

Affiliated researcher

PubMed DOI Crossref

Repeated LPS Injection Induces Distinct Changes in the Kynurenine Pathway in Mice.

Larsson MK, Faka A, Bhat M, ..., Schwieler L, Erhardt S

Neurochem. Res. 41 (9) 2243-2255 [2016-09-00; online 2016-05-10]

Affiliated researcher

PubMed DOI Crossref

Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways.

Erdem C, Nagle AM, Casa AJ, ..., Lee AV, Lezon TR

Mol. Cell Proteomics 15 (9) 3045-3057 [2016-09-00; online 2016-06-30]

Cemal Erdem DDLS Fellow

PubMed DOI Crossref

Protein profiles of CCL5, HPGDS, and NPSR1 in plasma reveal association with childhood asthma.

Hamsten C, Häggmark A, Grundström J, ..., Nilsson P, van Hage M

Allergy 71 (9) 1357-1361 [2016-09-00; online 2016-05-25]

Affiliated researcher

PubMed DOI Crossref

Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters.

Chen Y, Pai AA, Herudek J, ..., Jensen TH, Sandelin A

Nat. Genet. 48 (9) 984-994 [2016-09-00; online 2016-07-25]

Affiliated researcher SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Positron Emission Tomography to Assess the Outcome of Intraportal Islet Transplantation.

Eriksson O, Selvaraju R, Eich T, ..., Lundgren T, Korsgren O

Diabetes 65 (9) 2482-2489 [2016-09-00; online 2016-06-20]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Platelet-derived growth factor (PDGF)-induced activation of Erk5 MAP-kinase is dependent on Mekk2, Mek1/2, PKC and PI3-kinase, and affects BMP signaling.

Tsioumpekou M, Papadopoulos N, Burovic F, Heldin CH, Lennartsson J

Cell. Signal. 28 (9) 1422-1431 [2016-09-00; online 2016-06-21]

Affiliated researcher

PubMed DOI Crossref

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.

Perisic Matic L, Rykaczewska U, Razuvaev A, ..., Hamsten A, Hedin U

Arterioscler. Thromb. Vasc. Biol. 36 (9) 1947-1961 [2016-09-00; online 2016-07-28]

Affiliated researcher

PubMed DOI Crossref

Pancreatic perfusion and subsequent response to glucose in healthy individuals and patients with type 1 diabetes.

Carlbom L, Espes D, Lubberink M, ..., Ahlström H, Carlsson PO

Diabetologia 59 (9) 1968-1972 [2016-09-00; online 2016-06-16]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Oleate protects beta-cells from the toxic effect of palmitate by activating pro-survival pathways of the ER stress response.

Sargsyan E, Artemenko K, Manukyan L, Bergquist J, Bergsten P

Biochim. Biophys. Acta 1861 (9 Pt A) 1151-1160 [2016-09-00; online 2016-06-22]

Affiliated researcher

DOI Crossref

Microscale decoupling of sediment oxygen consumption and microbial biomass in an oligotrophic lake

Jeske JT, Müller RA, Wendeberg A, Bertilsson S

Freshw Biol 61 (9) 1477-1491 [2016-09-00; online 2016-06-17]

Affiliated researcher

PubMed DOI Crossref

Is low molecular weight hyaluronan an early indicator of disease in avian systemic sclerosis?

Kerje S, Hellman U, Do L, ..., Engström-Laurent A, Lindqvist U

Connect. Tissue Res. 57 (5) 337-346 [2016-09-00; online 2016-05-02]

Affiliated researcher

PubMed DOI Crossref

Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676.

Varnäs K, Juréus A, Johnström P, ..., Afzelius L, Farde L

J. Pharmacol. Exp. Ther. 358 (3) 464-471 [2016-09-00; online 2016-07-11]

Affiliated researcher

PubMed DOI Crossref

Human macrophages induce CD4(+)Foxp3(+) regulatory T cells via binding and re-release of TGF-β.

Schmidt A, Zhang XM, Joshi RN, ..., Harris RA, Tegnér J

Immunol. Cell Biol. 94 (8) 747-762 [2016-09-00; online 2016-05-10]

Affiliated researcher

PubMed DOI Crossref

How to talk about protein-level false discovery rates in shotgun proteomics.

The M, Tasnim A, Käll L

Proteomics 16 (18) 2461-2469 [2016-09-00; online 2016-08-10]

Affiliated researcher

PubMed DOI Crossref

Gender transition affects neural correlates of empathy: A resting state functional connectivity study with ultra high-field 7T MR imaging.

Spies M, Hahn A, Kranz GS, ..., Kasper S, Lanzenberger R

NeuroImage 138 (-) 257-265 [2016-09-00; online 2016-05-26]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Functional Relationship between a Dinoflagellate Host and Its Diatom Endosymbiont.

Hehenberger E, Burki F, Kolisko M, Keeling PJ

Mol. Biol. Evol. 33 (9) 2376-2390 [2016-09-00; online 2016-06-13]

Affiliated researcher Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Exploring the role of neuropeptide S in the regulation of arousal: a functional anatomical study.

Adori C, Barde S, Vas S, ..., Bagdy G, Hökfelt T

Brain Struct Funct 221 (7) 3521-3546 [2016-09-00; online 2015-10-13]

Affiliated researcher

PubMed DOI Crossref

Exploratory study of the association of steroid profiles in stimulated ovarian follicular fluid with outcomes of IVF treatment.

Kushnir MM, Naessén T, Wanggren K, ..., Meikle AW, Bergquist J

J. Steroid Biochem. Mol. Biol. 162 (-) 126-133 [2016-09-00; online 2015-09-24]

Affiliated researcher

PubMed DOI Crossref

Conformation Traits and Gaits in the Icelandic Horse are Associated with Genetic Variants in Myostatin (MSTN).

François L, Jäderkvist Fegraeus K, Eriksson S, ..., Lindgren G, Velie BD

J. Hered. 107 (5) 431-437 [2016-09-00; online 2016-05-13]

Affiliated researcher

PubMed DOI Crossref

Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord.

Zhang MD, Barde S, Szodorai E, ..., Harkany T, Hökfelt T

Brain Struct Funct 221 (7) 3803-3823 [2016-09-00; online 2016-02-02]

Affiliated researcher

PubMed DOI Crossref

Comparative analyses of quaternary arrangements in homo-oligomeric proteins in superfamilies: Functional implications.

Sudha G, Srinivasan N

Proteins 84 (9) 1190-1202 [2016-09-00; online 2016-06-08]

Affiliated researcher

PubMed DOI Crossref

Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond.

Rosenquist R, Rosenwald A, Du MQ, ..., Stamatopoulos K, European Research Initiative on CLL (ERIC) and the European Association for Haematopathology (EAHP)

Haematologica 101 (9) 1002-1009 [2016-09-00; online 2016-09-02]

Affiliated researcher

PubMed DOI Crossref

Chondrocytes Derived From Mesenchymal Stromal Cells and Induced Pluripotent Cells of Patients With Familial Osteochondritis Dissecans Exhibit an Endoplasmic Reticulum Stress Response and Defective Matrix Assembly.

Xu M, Stattin EL, Shaw G, ..., Murphy M, Barry F

Stem Cells Transl Med 5 (9) 1171-1181 [2016-09-00; online 2016-07-07]

Affiliated researcher

DOI Crossref

Benchmarking of algorithms for 3D tissue reconstruction

Kartasalo K, Latonen L, Visakorpi T, Nykter M, Ruusuvuori P

- - (-) 2360-2364 [2016-09-00; online 2016-09-00]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Autoantibody targets in vaccine-associated narcolepsy.

Häggmark-Månberg A, Zandian A, Forsström B, ..., Olsson T, Nilsson P

Autoimmunity 49 (6) 421-433 [2016-09-00; online 2016-05-20]

Affiliated researcher

PubMed DOI Crossref

Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes.

Leonard D, Eloranta ML, Hagberg N, ..., Alm G, Rönnblom L

Ann. Rheum. Dis. 75 (9) 1728-1734 [2016-09-00; online 2015-10-22]

Affiliated researcher

DOI Crossref

A software tool for studying the size and shape of human cardiomyocytes

Rasku J, Ojala M, Pölönen RP, ..., Aalto-Setälä K, Juhola M

Biomedical Signal Processing and Control 30 (-) 134-139 [2016-09-00; online 2016-09-00]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

A Significant Regulatory Mutation Burden at a High-Affinity Position of the CTCF Motif in Gastrointestinal Cancers.

Umer HM, Cavalli M, Dabrowski MJ, ..., Komorowski J, Wadelius C

Hum. Mutat. 37 (9) 904-913 [2016-09-00; online 2016-06-02]

Affiliated researcher

PubMed DOI Crossref

A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment.

Zaghlool A, Halvardson J, Zhao JJ, ..., Thuresson AC, Feuk L

Hum. Mutat. 37 (9) 964-975 [2016-09-00; online 2016-07-08]

Affiliated researcher

PubMed DOI Crossref

A Rickettsiales symbiont of amoebae with ancient features.

Schulz F, Martijn J, Wascher F, ..., Ettema TJ, Horn M

Environ. Microbiol. 18 (8) 2326-2342 [2016-09-00; online 2015-06-05]

Affiliated researcher

PubMed DOI Crossref

Origin of the U87MG glioma cell line: Good news and bad news.

Allen M, Bjerke M, Edlund H, Nelander S, Westermark B

Sci Transl Med 8 (354) 354re3 [2016-08-31; online 2016-09-02]

Affiliated researcher

PubMed DOI Crossref

The Adipose Transcriptional Response to Insulin Is Determined by Obesity, Not Insulin Sensitivity.

Rydén M, Hrydziuszko O, Mileti E, ..., Daub CO, Arner P

Cell Reports 16 (9) 2317-2326 [2016-08-30; online 2016-08-18]

Affiliated researcher

PubMed DOI Crossref

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study.

van der Laan SW, Fall T, Soumaré A, ..., Holmes MV, Asselbergs FW

J. Am. Coll. Cardiol. 68 (9) 934-945 [2016-08-30; online 2016-08-27]

Affiliated researcher

PubMed DOI Crossref

High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer.

Padhan N, Nordling TE, Sundström M, ..., Nelander S, Claesson-Welsh L

BMC Cancer 16 (1) 683 [2016-08-25; online 2016-08-25]

Affiliated researcher

PubMed DOI Crossref

The Competing Mechanisms of Phosphate Monoester Dianion Hydrolysis.

Duarte F, Barrozo A, Åqvist J, Williams NH, Kamerlin SC

J. Am. Chem. Soc. 138 (33) 10664-10673 [2016-08-24; online 2016-08-15]

Affiliated researcher

PubMed DOI Crossref

Enantioselective Organocatalyzed Transformations of β-Ketoesters.

Govender T, Arvidsson PI, Maguire GE, Kruger HG, Naicker T

Chem. Rev. 116 (16) 9375-9437 [2016-08-24; online 2016-07-27]

Affiliated researcher

PubMed DOI Crossref

An RGS2 3'UTR polymorphism is associated with preeclampsia in overweight women.

Karppanen T, Kaartokallio T, Klemetti MM, ..., Staff AC, Laivuori H

BMC Genet. 17 (1) 121 [2016-08-24; online 2016-08-24]

Affiliated researcher

PubMed DOI Crossref

Visualizing the Nonhomogeneous Structure of RAD51 Filaments Using Nanofluidic Channels.

Fornander LH, Frykholm K, Fritzsche J, ..., Modesti M, Westerlund F

Langmuir 32 (33) 8403-8412 [2016-08-23; online 2016-08-12]

Affiliated researcher

PubMed DOI Crossref

Tumor growth accelerated by chemotherapy-induced senescent cells is suppressed by treatment with IL-12 producing cellular vaccines.

Simova J, Sapega O, Imrichova T, ..., Hodny Z, Reinis M

Oncotarget 7 (34) 54952-54964 [2016-08-23; online 2016-07-28]

Affiliated researcher

PubMed DOI Crossref

S18 family of mitochondrial ribosomal proteins: evolutionary history and Gly132 polymorphism in colon carcinoma.

Mushtaq M, Ali RH, Kashuba V, Klein G, Kashuba E

Oncotarget 7 (34) 55649-55662 [2016-08-23; online 2016-08-05]

Affiliated researcher

PubMed DOI Crossref

Ras and TGF-β signaling enhance cancer progression by promoting the ΔNp63 transcriptional program.

Vasilaki E, Morikawa M, Koinuma D, ..., Miyazono K, Heldin CH

Sci Signal 9 (442) ra84 [2016-08-23; online 2016-08-23]

Affiliated researcher

PubMed DOI Crossref

Oxidation and cyclization of casbene in the biosynthesis of Euphorbia factors from mature seeds of Euphorbia lathyris L.

Luo D, Callari R, Hamberger B, ..., Staerk D, Hamberger B

Proc. Natl. Acad. Sci. U.S.A. 113 (34) E5082-E5089 [2016-08-23; online 2016-08-09]

Affiliated researcher

PubMed DOI Crossref

Single base resolution analysis of 5-hydroxymethylcytosine in 188 human genes: implications for hepatic gene expression.

Ivanov M, Kals M, Lauschke V, ..., Milani L, Ingelman-Sundberg M

Nucleic Acids Res. 44 (14) 6756-6769 [2016-08-19; online 2016-04-29]

Affiliated researcher

PubMed DOI Crossref

Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation.

Oommen OP, Duehrkop C, Nilsson B, Hilborn J, Varghese OP

ACS Appl Mater Interfaces 8 (32) 20614-20624 [2016-08-17; online 2016-08-05]

Affiliated researcher

PubMed DOI Crossref

Label-free detection of real-time DNA amplification using a nanofluidic diffraction grating.

Yasui T, Ogawa K, Kaji N, ..., Horiike Y, Baba Y

Sci Rep 6 (-) 31642 [2016-08-17; online 2016-08-17]

Affiliated researcher

PubMed DOI Crossref

Multiplex PCB-based electrochemical detection of cancer biomarkers using MLPA-barcode approach.

Sánchez JL, Henry OY, Joda H, ..., Riley I, O'Sullivan CK

Biosens Bioelectron 82 (-) 224-232 [2016-08-15; online 2016-04-07]

Affiliated researcher

PubMed DOI Crossref

Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis.

Menard JA, Christianson HC, Kucharzewska P, ..., Johansson MC, Belting M

Cancer Res. 76 (16) 4828-4840 [2016-08-15; online 2016-05-19]

Affiliated researcher

PubMed DOI Crossref

A Deeper Look into Type 1 Diabetes - Imaging Immune Responses during Onset of Disease.

Christoffersson G, von Herrath MG

Front Immunol 7 (-) 313 [2016-08-15; online 2016-08-15]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

The diagnosis of pre-eclampsia using two revised classifications in the Finnish Pre-eclampsia Consortium (FINNPEC) cohort.

Kallela J, Jääskeläinen T, Kortelainen E, ..., Pouta A, Laivuori H

BMC Pregnancy Childbirth 16 (-) 221 [2016-08-12; online 2016-08-12]

Affiliated researcher

DOI Crossref

Mixed cultures as model communities: hunting for ubiquitous microorganisms, their partners, and interactions

Garcia S

Aquat. Microb. Ecol. 77 (2) 79-85 [2016-08-12; online 2016-08-12]

Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

Stratification of responders towards eculizumab using a structural epitope mapping strategy.

Volk AL, Hu FJ, Berglund MM, ..., Uhlen M, Rockberg J

Sci Rep 6 (-) 31365 [2016-08-11; online 2016-08-11]

Affiliated researcher

PubMed DOI Crossref

Global profiling of SRP interaction with nascent polypeptides.

Schibich D, Gloge F, Pöhner I, ..., Bukau B, Kramer G

Nature 536 (7615) 219-223 [2016-08-11; online 2016-08-03]

Affiliated researcher

PubMed DOI Crossref

Enzyme overexpression - an exercise toward understanding regulation of heparan sulfate biosynthesis.

Fang J, Song T, Lindahl U, Li JP

Sci Rep 6 (-) 31242 [2016-08-11; online 2016-08-11]

Affiliated researcher

PubMed DOI Crossref

Large-scale ligand-based predictive modelling using support vector machines.

Alvarsson J, Lampa S, Schaal W, ..., Wikberg JE, Spjuth O

J Cheminform 8 (-) 39 [2016-08-10; online 2016-08-10]

Affiliated researcher

PubMed DOI Crossref

IFN-γ Hinders Recovery from Mucosal Inflammation during Antibiotic Therapy for Salmonella Gut Infection.

Dolowschiak T, Mueller AA, Pisan LJ, ..., Mueller C, Hardt WD

Cell Host Microbe 20 (2) 238-249 [2016-08-10; online 2016-07-21]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Role of Conserved Gly-Gly Pairs on the Periplasmic Side of LacY.

Jiang X, Andersson M, Chau BT, ..., Villafuerte MK, Kaback HR

Biochemistry 55 (31) 4326-4332 [2016-08-09; online 2016-08-01]

Affiliated researcher

PubMed DOI Crossref

Production of hemolysin BL by Bacillus cereus group isolates of dairy origin is associated with whole-genome phylogenetic clade.

Kovac J, Miller RA, Carroll LM, ..., Beno SM, Wiedmann M

BMC Genomics 17 (-) 581 [2016-08-09; online 2016-08-09]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection.

López-Saavedra A, Gómez-Cabello D, Domínguez-Sánchez MS, ..., Bartek J, Huertas P

Nat Commun 7 (-) 12364 [2016-08-09; online 2016-08-09]

Affiliated researcher

PubMed DOI Crossref

Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.

Gerling M, Büller NV, Kirn LM, ..., van den Brink GR, Toftgård R

Nat Commun 7 (-) 12321 [2016-08-05; online 2016-08-05]

Affiliated researcher

PubMed DOI Crossref

Photoswitchable Spiropyran Dyads for Biological Imaging.

Xiong Y, Rivera-Fuentes P, Sezgin E, ..., Eggeling C, Anderson HL

Org. Lett. 18 (15) 3666-3669 [2016-08-05; online 2016-07-26]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Integration of a Droplet-Based Microfluidic System and Silicon Nanoribbon FET Sensor.

Afrasiabi R, Soderberg LM, Joensson HN, ..., Andersson Svahn H, Linnros J

Micromachines (Basel) 7 (8) - [2016-08-05; online 2016-08-05]

Affiliated researcher

PubMed DOI Crossref

The genetic architecture of type 2 diabetes.

Fuchsberger C, Flannick J, Teslovich TM, ..., Altshuler D, McCarthy MI

Nature 536 (7614) 41-47 [2016-08-04; online 2016-07-11]

Affiliated researcher

PubMed DOI Crossref

Molecular Dynamics Simulation Study of Parallel Telomeric DNA Quadruplexes at Different Ionic Strengths: Evaluation of Water and Ion Models.

Rebič M, Laaksonen A, Šponer J, Uličný J, Mocci F

J Phys Chem B 120 (30) 7380-7391 [2016-08-04; online 2016-07-26]

Affiliated researcher

PubMed DOI Crossref

The chaperone co-inducer BGP-15 alleviates ventilation-induced diaphragm dysfunction.

Salah H, Li M, Cacciani N, ..., Salviati L, Larsson L

Sci Transl Med 8 (350) 350ra103 [2016-08-03; online 2016-08-05]

Affiliated researcher

PubMed DOI Crossref

B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing.

Mohammad DK, Ali RH, Turunen JJ, Nore BF, Smith CI

PLoS ONE 11 (8) e0160255 [2016-08-03; online 2016-08-03]

Affiliated researcher

PubMed DOI Crossref

Compounds from the marine sponge Cribrochalina vasculum offer a way to target IGF-1R mediated signaling in tumor cells.

Zovko A, Novak M, Hååg P, ..., Lewensohn R, Viktorsson K

Oncotarget 7 (31) 50258-50276 [2016-08-02; online 2016-07-08]

Affiliated researcher

PubMed DOI Crossref

Tumor-Induced NETosis as a Risk Factor for Metastasis and Organ Failure.

Cedervall J, Zhang Y, Olsson AK

Cancer Res. 76 (15) 4311-4315 [2016-08-01; online 2016-07-11]

Affiliated researcher

PubMed DOI Crossref

TreeDom: a graphical web tool for analysing domain architecture evolution.

Haider C, Kavic M, Sonnhammer EL

Bioinformatics 32 (15) 2384-2385 [2016-08-01; online 2016-03-12]

Affiliated researcher

PubMed DOI Crossref

Targeting Suppressive Myeloid Cells Potentiates Checkpoint Inhibitors to Control Spontaneous Neuroblastoma.

Mao Y, Eissler N, Blanc KL, ..., Kogner P, Kiessling R

Clin. Cancer Res. 22 (15) 3849-3859 [2016-08-01; online 2016-03-08]

SciLifeLab Fellow Yumeng Mao

PubMed DOI Crossref

Simulated single molecule microscopy with SMeagol.

Lindén M, Ćurić V, Boucharin A, Fange D, Elf J

Bioinformatics 32 (15) 2394-2395 [2016-08-01; online 2016-03-04]

Affiliated researcher

PubMed DOI Crossref

Signaling Receptors for TGF-β Family Members.

Heldin CH, Moustakas A

Cold Spring Harbor Perspectives in Biology 8 (8) - [2016-08-01; online 2016-08-01]

Affiliated researcher

PubMed DOI Crossref

Profilin connects actin assembly with microtubule dynamics.

Nejedla M, Sadi S, Sulimenko V, ..., Aspenström P, Karlsson R

Mol. Biol. Cell 27 (15) 2381-2393 [2016-08-01; online 2016-06-15]

Affiliated researcher

PubMed DOI Crossref

On the reversibility of parasitism: adaptation to a free-living lifestyle via gene acquisitions in the diplomonad Trepomonas sp. PC1.

Xu F, Jerlström-Hultqvist J, Kolisko M, ..., Svärd SG, Andersson JO

BMC Biol. 14 (-) 62 [2016-08-01; online 2016-08-01]

Affiliated researcher

PubMed DOI Crossref

Adaptation to different types of stress converge on mitochondrial metabolism.

Lahtvee PJ, Kumar R, Hallström BM, Nielsen J

Mol. Biol. Cell 27 (15) 2505-2514 [2016-08-01; online 2016-06-15]

Affiliated researcher

PubMed DOI Crossref

Tuning fresh: radiation through rewiring of central metabolism in streamlined bacteria.

Eiler A, Mondav R, Sinclair L, ..., Woyke T, Bertilsson S

ISME J 10 (8) 1902-1914 [2016-08-00; online 2016-01-19]

Affiliated researcher

PubMed DOI Crossref

Transcriptomic analysis reveals how a lack of potassium ions increases Sulfolobus acidocaldarius sensitivity to pH changes.

Buetti-Dinh A, Dethlefsen O, Friedman R, Dopson M

Microbiology (Reading, Engl.) 162 (8) 1422-1434 [2016-08-00; online 2016-05-26]

Affiliated researcher

PubMed DOI Crossref

Skeletal response to diet with soya bean seeds used as primary source of protein in growing broiler chickens.

Olkowski B, Charuta A, Radzki R, Bieńko M, Toczko R

Journal of animal physiology and animal nutrition 100 (4) 731-737 [2016-08-00; online 2016-02-08]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction.

Mooijman D, Dey SS, Boisset JC, Crosetto N, van Oudenaarden A

Nat. Biotechnol. 34 (8) 852-856 [2016-08-00; online 2016-06-27]

Affiliated researcher

PubMed DOI Crossref

SATB2 is expressed in Merkel cell carcinoma.

Fukuhara M, Agnarsdóttir M, Edqvist PH, Coter A, Ponten F

Arch. Dermatol. Res. 308 (6) 449-454 [2016-08-00; online 2016-06-04]

Affiliated researcher

PubMed DOI Crossref

Rapid Evolution of Genomic Imprinting in Two Species of the Brassicaceae.

Hatorangan MR, Laenen B, Steige KA, Slotte T, Köhler C

Plant Cell 28 (8) 1815-1827 [2016-08-00; online 2016-07-27]

Affiliated researcher SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Quantification of β-Cell Mass in Intramuscular Islet Grafts Using Radiolabeled Exendin-4.

Espes D, Selvaraju R, Velikyan I, ..., Carlsson PO, Eriksson O

Transplantation direct 2 (8) e93 [2016-08-00; online 2016-07-22]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Probing amyloid-β pathology in transgenic Alzheimer's disease (tgArcSwe) mice using MALDI imaging mass spectrometry.

Carlred L, Michno W, Kaya I, ..., Syvänen S, Hanrieder J

J. Neurochem. 138 (3) 469-478 [2016-08-00; online 2016-05-26]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Pathways controlling dNTP pools to maintain genome stability.

Rudd SG, Valerie NCK, Helleday T

DNA Repair (Amst.) 44 (-) 193-204 [2016-08-00; online 2016-05-28]

Affiliated researcher

PubMed DOI Crossref

Otopalatodigital spectrum disorders: refinement of the phenotypic and mutational spectrum.

Moutton S, Fergelot P, Naudion S, ..., Goizet C, Coupry I

J. Hum. Genet. 61 (8) 693-699 [2016-08-00; online 2016-05-19]

Affiliated researcher

PubMed DOI Crossref

Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose.

Cavalli M, Pan G, Nord H, ..., Wadelius C, Wadelius M

Pharmacogenomics 17 (12) 1305-1314 [2016-08-00; online 2016-02-05]

Affiliated researcher

PubMed DOI Crossref

Neuroprotective potential of Linezolid: a quantitative and distribution study via mass spectrometry.

Baijnath S, Shobo A, Bester LA, ..., Naicker T, Govender T

J. Mol. Histol. 47 (4) 429-435 [2016-08-00; online 2016-06-21]

Affiliated researcher

PubMed DOI Crossref

NF-κB activation in chronic lymphocytic leukemia: A point of convergence of external triggers and intrinsic lesions.

Mansouri L, Papakonstantinou N, Ntoufa S, Stamatopoulos K, Rosenquist R

Semin. Cancer Biol. 39 (-) 40-48 [2016-08-00; online 2016-08-01]

Affiliated researcher

PubMed DOI Crossref

Liver: Phenotypic and genetic variance: a systems approach to the liver.

Mardinoglu A, Uhlén M

Nat Rev Gastroenterol Hepatol 13 (8) 439-440 [2016-08-00; online 2016-06-22]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Initial hyperinsulinemia and subsequent β-cell dysfunction is associated with elevated palmitate levels.

Staaf J, Ubhayasekera SJ, Sargsyan E, ..., Forslund A, Bergsten P

Pediatr. Res. 80 (2) 267-274 [2016-08-00; online 2016-04-11]

Affiliated researcher

PubMed DOI Crossref

Impact of ocean acidification on antimicrobial activity in gills of the blue mussel (Mytilus edulis).

Hernroth B, Baden S, Tassidis H, ..., Bergström Lind S, Bergquist J

Fish Shellfish Immunol. 55 (-) 452-459 [2016-08-00; online 2016-06-08]

Affiliated researcher

PubMed DOI Crossref

Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

Morris DL, Sheng Y, Zhang Y, ..., Cui Y, Vyse TJ

Nat. Genet. 48 (8) 940-946 [2016-08-00; online 2016-07-11]

Affiliated researcher

PubMed DOI Crossref

Genetic determinants of warfarin maintenance dose and time in therapeutic treatment range: a RE-LY genomics substudy.

Eriksson N, Wallentin L, Berglund L, ..., Yusuf S, Wadelius M

Pharmacogenomics 17 (13) 1425-1439 [2016-08-00; online 2016-08-04]

Affiliated researcher

PubMed DOI Crossref

Evidence for genetic regulation of the human parieto-occipital 10-Hz rhythmic activity.

Salmela E, Renvall H, Kujala J, ..., Salmelin R, Kere J

Eur. J. Neurosci. 44 (3) 1963-1971 [2016-08-00; online 2016-07-04]

Affiliated researcher

PubMed DOI Crossref

Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors.

Sutton LA, Young E, Baliakas P, ..., Rosenquist R, ERIC, the European Research Initiative on CLL

Haematologica 101 (8) 959-967 [2016-08-00; online 2016-05-19]

Affiliated researcher

PubMed DOI Crossref

Different Alleles of a Gene Encoding Leucoanthocyanidin Reductase (PaLAR3) Influence Resistance against the Fungus Heterobasidion parviporum in Picea abies.

Nemesio-Gorriz M, Hammerbacher A, Ihrmark K, ..., Gershenzon J, Elfstrand M

Plant Physiol. 171 (4) 2671-2681 [2016-08-00; online 2016-06-17]

Affiliated researcher

PubMed DOI Crossref

Coordinated disassembly of the divisome complex in Escherichia coli.

Söderström B, Mirzadeh K, Toddo S, ..., Skoglund U, Daley DO

Mol. Microbiol. 101 (3) 425-438 [2016-08-00; online 2016-05-23]

Affiliated researcher

PubMed DOI Crossref

Acoustic micro-vortexing of fluids, particles and cells in disposable microfluidic chips.

Iranmanesh I, Ohlin M, Ramachandraiah H, ..., Russom A, Wiklund M

Biomed Microdevices 18 (4) 71 [2016-08-00; online 2016-07-23]

Affiliated researcher

PubMed DOI Crossref

A novel splicing mutation in the IQSEC2 gene that modulates the phenotype severity in a family with intellectual disability.

Madrigal I, Alvarez-Mora MI, Rosell J, ..., Syvänen AC, Mila M

Eur. J. Hum. Genet. 24 (8) 1117-1123 [2016-08-00; online 2016-01-06]

Affiliated researcher

PubMed DOI Crossref

A Longitudinal Follow-up of Autoimmune Polyendocrine Syndrome Type 1.

Bruserud Ø, Oftedal BE, Landegren N, ..., Wolff AB, Husebye ES

J. Clin. Endocrinol. Metab. 101 (8) 2975-2983 [2016-08-00; online 2016-06-02]

Affiliated researcher

PubMed DOI Crossref

Identification of combinatorial host-specific signatures with a potential to affect host adaptation in influenza A H1N1 and H3N2 subtypes.

Khaliq Z, Leijon M, Belák S, Komorowski J

BMC Genomics 17 (-) 529 [2016-07-29; online 2016-07-29]

Affiliated researcher

PubMed DOI Crossref

The Synchronization of Replication and Division Cycles in Individual E. coli Cells.

Wallden M, Fange D, Lundius EG, Baltekin Ö, Elf J

Cell 166 (3) 729-739 [2016-07-28; online 2016-07-30]

Affiliated researcher

PubMed DOI Crossref

Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.

Brunner K, Maric S, Reshma RS, ..., Schnell R, Schneider G

J. Med. Chem. 59 (14) 6848-6859 [2016-07-28; online 2016-07-13]

Affiliated researcher

PubMed DOI Crossref

Identification of Novel Transcribed Regions in Zebrafish (Danio rerio) Using RNA-Sequencing.

Wang J, Vesterlund L, Kere J, Jiao H

PLoS ONE 11 (7) e0160197 [2016-07-27; online 2016-07-27]

Affiliated researcher

PubMed DOI Crossref

Human cytomegalovirus may promote tumour progression by upregulating arginase-2.

Costa H, Xu X, Overbeek G, ..., Söderberg-Naucler C, Yaiw KC

Oncotarget 7 (30) 47221-47231 [2016-07-26; online 2016-07-01]

Affiliated researcher

PubMed DOI Crossref

ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells.

Wee B, Pietras A, Ozawa T, ..., Michor F, Holland EC

Sci Rep 6 (-) 25956 [2016-07-26; online 2016-07-26]

Affiliated researcher

PubMed DOI Crossref

Computer-Aided Production of Scaffolded DNA Nanostructures from Flat Sheet Meshes.

Benson E, Mohammed A, Bosco A, ..., Orponen P, Högberg B

Angew. Chem. Int. Ed. Engl. 55 (31) 8869-8872 [2016-07-25; online 2016-06-15]

Erik Benson SciLifeLab Fellow

PubMed DOI Crossref

Computational studies of human class V alcohol dehydrogenase - the odd sibling.

Östberg LJ, Persson B, Höög JO

BMC Biochem. 17 (1) 16 [2016-07-25; online 2016-07-25]

Affiliated researcher

PubMed

The importance of the type I interferon system in autoimmunity.

Rönnblom L

Clin. Exp. Rheumatol. 34 (4 Suppl 98) 21-24 [2016-07-21; online 2016-07-21]

Affiliated researcher

PubMed DOI Crossref

Preclinical Evaluation of AdVince, an Oncolytic Adenovirus Adapted for Treatment of Liver Metastases from Neuroendocrine Cancer.

Yu D, Leja-Jarblad J, Loskog A, ..., Oberg K, Essand M

Neuroendocrinology 105 (1) 54-66 [2016-07-21; online 2016-07-21]

Affiliated researcher

PubMed DOI Crossref

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation.

Carthy JM, Stöter M, Bellomo C, ..., Heldin CH, Moustakas A

Sci Rep 6 (-) 29868 [2016-07-19; online 2016-07-19]

Affiliated researcher

PubMed DOI Crossref

Identification of meat products by shotgun spectral matching.

Ohana D, Dalebout H, Marissen RJ, ..., Deelder AM, Palmblad M

Food Chem 203 (-) 28-34 [2016-07-15; online 2016-02-02]

Affiliated researcher

PubMed DOI Crossref

Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification.

Reischauer S, Stone OA, Villasenor A, ..., Andersson O, Stainier DY

Nature 535 (7611) 294-298 [2016-07-14; online 2016-07-15]

Affiliated researcher

PubMed DOI Crossref

Human serum-derived protein removes the need for coating in defined human pluripotent stem cell culture.

Pijuan-Galitó S, Tamm C, Schuster J, ..., Merry CL, Annerén C

Nat Commun 7 (-) 12170 [2016-07-13; online 2016-07-13]

Affiliated researcher

DOI Crossref

Electron transition pathways of photoluminescence from 3C-SiC nanocrystals unraveled by steady-state, blinking and time-resolved photoluminescence measurements

Gan Z, Wu X, Xu H, ..., Nie S, Fu Y

J. Phys. D: Appl. Phys. 49 (27) 275107 [2016-07-13; online 2016-06-14]

Affiliated researcher

PubMed DOI Crossref

Avidity characterization of genetically engineered T-cells with novel and established approaches.

Hillerdal V, Boura VF, Björkelund H, Andersson K, Essand M

BMC Immunol. 17 (1) 23 [2016-07-13; online 2016-07-13]

Affiliated researcher

PubMed DOI Crossref

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer.

Jarvis D, Mitchell JS, Law PJ, ..., Tomlinson IP, Houlston RS

Br. J. Cancer 115 (2) 266-272 [2016-07-12; online 2016-06-23]

Affiliated researcher

PubMed DOI Crossref

Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance.

Lee S, Zhang C, Kilicarslan M, ..., Boren J, Mardinoglu A

Cell Metab. 24 (1) 172-184 [2016-07-12; online 2016-06-23]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Directly linked hydroporphyrin dimers.

Xiong R, Arkhypchuk AI, Kovacs D, Orthaber A, Eszter Borbas K

Chem. Commun. (Camb.) 52 (58) 9056-9058 [2016-07-12; online 2016-02-10]

Ruisheng Xiong SciLifeLab Fellow

PubMed DOI Crossref

5-Hydroxymethylcytosine Remodeling Precedes Lineage Specification during Differentiation of Human CD4(+) T Cells.

Nestor CE, Lentini A, Hägg Nilsson C, ..., Zhang H, Benson M

Cell Reports 16 (2) 559-570 [2016-07-12; online 2016-06-23]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

PathwAX: a web server for network crosstalk based pathway annotation.

Ogris C, Helleday T, Sonnhammer EL

Nucleic Acids Res. 44 (W1) W105-W109 [2016-07-08; online 2016-05-05]

Affiliated researcher

PubMed DOI Crossref

Local Adaptation in European Firs Assessed through Extensive Sampling across Altitudinal Gradients in Southern Europe.

Brousseau L, Postolache D, Lascoux M, ..., Fady B, Vendramin GG

PLoS ONE 11 (7) e0158216 [2016-07-08; online 2016-07-08]

Affiliated researcher

PubMed DOI Crossref

Dysregulated signaling hubs of liver lipid metabolism reveal hepatocellular carcinoma pathogenesis.

Lee S, Mardinoglu A, Zhang C, Lee D, Nielsen J

Nucleic Acids Res. 44 (12) 5529-5539 [2016-07-08; online 2016-05-23]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Large Deletions at the SHOX Locus in the Pseudoautosomal Region Are Associated with Skeletal Atavism in Shetland Ponies.

Rafati N, Andersson LS, Mikko S, ..., Lindgren G, Rubin CJ

G3 6 (7) 2213-2223 [2016-07-07; online 2016-07-07]

Affiliated researcher

PubMed DOI Crossref

Identifying Genetic Signatures of Natural Selection Using Pooled Population Sequencing in Picea abies.

Chen J, Källman T, Ma XF, ..., Morgante M, Lascoux M

G3 6 (7) 1979-1989 [2016-07-07; online 2016-07-07]

Affiliated researcher

PubMed DOI Crossref

Exome sequencing in pooled DNA samples to identify maternal pre-eclampsia risk variants.

Kaartokallio T, Wang J, Heinonen S, ..., Kere J, Laivuori H

Sci Rep 6 (-) 29085 [2016-07-07; online 2016-07-07]

Affiliated researcher

PubMed DOI Crossref

Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer.

Mezheyeuski A, Bradic Lindh M, Guren TK, ..., Sorbye H, Östman A

Oncotarget 7 (27) 41948-41958 [2016-07-05; online 2016-06-02]

Affiliated researcher

PubMed DOI Crossref

Pooled analysis of genome-wide association studies of cervical intraepithelial neoplasia 3 (CIN3) identifies a new susceptibility locus.

Chen D, Enroth S, Liu H, ..., Xu S, Gyllensten U

Oncotarget 7 (27) 42216-42224 [2016-07-05; online 2016-06-11]

Affiliated researcher

PubMed DOI Crossref

Estrogen receptor beta reduces colon cancer metastasis through a novel miR-205 - PROX1 mechanism.

Nguyen-Vu T, Wang J, Mesmar F, ..., Bondesson M, Williams C

Oncotarget 7 (27) 42159-42171 [2016-07-05; online 2016-06-11]

Affiliated researcher

PubMed DOI Crossref

Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer.

Kangaspeska S, Hultsch S, Jaiswal A, ..., Aittokallio T, Kallioniemi O

BMC Cancer 16 (-) 378 [2016-07-04; online 2016-07-04]

Affiliated researcher

PubMed DOI Crossref

Molecular Evolutionary Consequences of Island Colonization.

James JE, Lanfear R, Eyre-Walker A

Genome Biol Evol 8 (6) 1876-1888 [2016-07-02; online 2016-07-02]

DDLS Fellow Jennifer James

PubMed DOI Crossref

Visualization and analysis of gene expression in tissue sections by spatial transcriptomics.

Ståhl PL, Salmén F, Vickovic S, ..., Lundeberg J, Frisén J

Science (New York, N.Y.) 353 (6294) 78-82 [2016-07-01; online 2016-07-02]

Affiliated researcher Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment.

van Hooren L, Georganaki M, Huang H, Mangsbo SM, Dimberg A

Oncotarget 7 (31) 50277-50289 [2016-07-01; online 2016-07-08]

Affiliated researcher

PubMed DOI Crossref

PON-Sol: prediction of effects of amino acid substitutions on protein solubility.

Yang Y, Niroula A, Shen B, Vihinen M

Bioinformatics 32 (13) 2032-2034 [2016-07-01; online 2016-02-19]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Hyaluronic acid-fibrin interpenetrating double network hydrogel prepared in situ by orthogonal disulfide cross-linking reaction for biomedical applications.

Zhang Y, Heher P, Hilborn J, Redl H, Ossipov DA

Acta Biomater 38 (-) 23-32 [2016-07-01; online 2016-04-28]

Affiliated researcher

PubMed DOI Crossref

Assembly scaffolding with PE-contaminated mate-pair libraries.

Sahlin K, Chikhi R, Arvestad L

Bioinformatics 32 (13) 1925-1932 [2016-07-01; online 2016-03-02]

Affiliated researcher Kristoffer Sahlin SciLifeLab Fellow

PubMed DOI Crossref

The role of germline alterations in the DNA damage response genes BRIP1 and BRCA2 in melanoma susceptibility.

Tuominen R, Engström PG, Helgadottir H, ..., Hansson J, Höiom V

Genes Chromosomes Cancer 55 (7) 601-611 [2016-07-00; online 2016-05-02]

Affiliated researcher

PubMed DOI Crossref

Tandem mass spectrometry determined maternal cortisone to cortisol ratio and psychiatric morbidity during pregnancy-interaction with birth weight.

Hellgren C, Edvinsson Å, Olivier JD, ..., Bergquist J, Sundström-Poromaa I

Psychoneuroendocrinology 69 (-) 142-149 [2016-07-00; online 2016-04-07]

Affiliated researcher

PubMed DOI Crossref

Super-resolution structured illumination fluorescence microscopy of the lateral wall of the cochlea: the Connexin26/30 proteins are separately expressed in man.

Liu W, Edin F, Blom H, ..., Laurell G, Rask-Andersen H

Cell Tissue Res. 365 (1) 13-27 [2016-07-00; online 2016-03-04]

Affiliated researcher

PubMed DOI Crossref

Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer.

Jin C, Fotaki G, Ramachandran M, ..., Essand M, Yu D

EMBO Mol Med 8 (7) 702-711 [2016-07-00; online 2016-07-01]

Affiliated researcher

PubMed DOI Crossref

Regulation of the TGF-β pathway by deubiquitinases in cancer.

Liu S, de Boeck M, van Dam H, Ten Dijke P

Int. J. Biochem. Cell Biol. 76 (-) 135-145 [2016-07-00; online 2016-05-04]

Affiliated researcher

PubMed DOI Crossref

Prevention of apoptosis averts glomerular tubular disconnection and podocyte loss in proteinuric kidney disease.

Burlaka I, Nilsson LM, Scott L, ..., Brismar H, Aperia A

Kidney Int. 90 (1) 135-148 [2016-07-00; online 2016-05-21]

Affiliated researcher

PubMed DOI Crossref

Physical and verbal aggressive behavior and COMT genotype: Sensitivity to the environment.

Tuvblad C, Narusyte J, Comasco E, ..., Fanti KA, Nilsson KW

Am. J. Med. Genet. B Neuropsychiatr. Genet. 171 (5) 708-718 [2016-07-00; online 2016-02-17]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

PDMS-Based Elastomer Tuned Soft, Stretchable, and Sticky for Epidermal Electronics.

Jeong SH, Zhang S, Hjort K, Hilborn J, Wu Z

Adv. Mater. Weinheim 28 (28) 5830-5836 [2016-07-00; online 2016-05-11]

Affiliated researcher

DOI Crossref

Morphological stability of microencapsulated vitamin formulations by AFM imaging

Mougin K, Bruntz A, Severin D, Teleki A

Food Structure 9 (-) 1-12 [2016-07-00; online 2016-07-00]

Alexandra Teleki SciLifeLab Fellow

DOI Crossref

Measurement‐based wireless network planning, monitoring, and reconfiguration solution for robust radio communications in indoor factories

Gong X, Trogh J, Braet Q, ..., Martens L, Joseph W

IET Science, Measurement & Technology 10 (4) 375-382 [2016-07-00; online 2016-07-00]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome.

Harris VM, Sharma R, Cavett J, ..., Sivils KL, Scofield RH

Clin. Immunol. 168 (-) 25-29 [2016-07-00; online 2016-04-22]

Affiliated researcher

PubMed DOI Crossref

In vivo imaging of beta cells with radiotracers: state of the art, prospects and recommendations for development and use.

Eriksson O, Laughlin M, Brom M, ..., Bonadonna R, Gotthardt M

Diabetologia 59 (7) 1340-1349 [2016-07-00; online 2016-04-19]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Genome-wide selective sweeps and gene-specific sweeps in natural bacterial populations.

Bendall ML, Stevens SL, Chan LK, ..., McMahon KD, Malmstrom RR

ISME J 10 (7) 1589-1601 [2016-07-00; online 2016-01-08]

Affiliated researcher

PubMed DOI Crossref

Functional characterization of neurotransmitter activation and modulation in a nematode model ligand-gated ion channel.

Heusser SA, Yoluk Ö, Klement G, ..., Lindahl E, Howard RJ

J. Neurochem. 138 (2) 243-253 [2016-07-00; online 2016-05-25]

Affiliated researcher

PubMed DOI Crossref

Distinct transcription factor complexes act on a permissive chromatin landscape to establish regionalized gene expression in CNS stem cells.

Hagey DW, Zaouter C, Combeau G, ..., Huss M, Muhr J

Genome Res. 26 (7) 908-917 [2016-07-00; online 2016-05-02]

Affiliated researcher

PubMed DOI Crossref

Corticotropin-releasing hormone family evolution: five ancestral genes remain in some lineages.

Cardoso JC, Bergqvist CA, Félix RC, Larhammar D

J. Mol. Endocrinol. 57 (1) 73-86 [2016-07-00; online 2016-05-24]

Affiliated researcher

PubMed DOI Crossref

Corticolimbic anatomical characteristics predetermine risk for chronic pain.

Vachon-Presseau E, Tétreault P, Petre B, ..., Baliki MN, Apkarian AV

Brain 139 (Pt 7) 1958-1970 [2016-07-00; online 2016-05-05]

Affiliated researcher Erika Comasco SciLifeLab Fellow

DOI Crossref

Constraints on methane oxidation in ice-covered boreal lakes

Denfeld BA, Ricão Canelhas M, Weyhenmeyer GA, ..., Eiler A, Bastviken D

J. Geophys. Res. Biogeosci. 121 (7) 1924-1933 [2016-07-00; online 2016-07-22]

Affiliated researcher

PubMed DOI Crossref

Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication.

Schulte T, Liu L, Panas MD, ..., Achour A, McInerney GM

Open Biol 6 (7) - [2016-07-00; online 2016-07-08]

Affiliated researcher

PubMed DOI Crossref

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing.

Galanos P, Vougas K, Walter D, ..., Bartek J, Gorgoulis VG

Nat. Cell Biol. 18 (7) 777-789 [2016-07-00; online 2016-06-20]

Affiliated researcher

PubMed DOI Crossref

Chronic kidney disease and 10-year risk of cardiovascular death.

Holzmann MJ, Carlsson AC, Hammar N, ..., Wändell P, Ärnlöv J

Eur J Prev Cardiol 23 (11) 1187-1194 [2016-07-00; online 2015-11-05]

Affiliated researcher

PubMed DOI Crossref

Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs.

Rydén A, Nyman G, Nalin L, ..., Eriksson O, Jensen-Waern M

Nucl. Med. Biol. 43 (7) 397-402 [2016-07-00; online 2016-04-16]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Application of a Nonlinear Model to Transcript Levels of Upregulated Stress Response Gene ibpA in Stationary-Phase Salmonella enterica Subjected to Sublethal Heat Stress.

Carroll LM, Bergholz TM, Hildebrandt IM, Marks BP

J Food Prot 79 (7) 1089-1096 [2016-07-00; online 2016-07-01]

DDLS Fellow Laura Carroll

PubMed DOI Crossref

Antagonists of IGF:Vitronectin Interactions Inhibit IGF-I-Induced Breast Cancer Cell Functions.

Kashyap AS, Shooter GK, Shokoohmand A, ..., Upton Z, Hollier BG

Mol. Cancer Ther. 15 (7) 1602-1613 [2016-07-00; online 2016-05-09]

Affiliated researcher

PubMed DOI Crossref

A draft fur seal genome provides insights into factors affecting SNP validation and how to mitigate them.

Humble E, Martinez-Barrio A, Forcada J, ..., Wolf JB, Hoffman JI

Mol Ecol Resour 16 (4) 909-921 [2016-07-00; online 2016-01-20]

Affiliated researcher

PubMed DOI Crossref

UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly.

Hunziker M, Barandun J, Petfalski E, ..., Tollervey D, Klinge S

Nat Commun 7 (-) 12090 [2016-06-29; online 2016-06-29]

Jonas Barandun SciLifeLab Fellow

PubMed DOI Crossref

Multiple regulatory variants located in cell type-specific enhancers within the PKP2 locus form major risk and protective haplotypes for canine atopic dermatitis in German shepherd dogs.

Tengvall K, Kozyrev S, Kierczak M, ..., Andersson G, Lindblad-Toh K

BMC Genet. 17 (1) 97 [2016-06-29; online 2016-06-29]

Affiliated researcher

PubMed DOI Crossref

Heparanase expression upregulates platelet adhesion activity and thrombogenicity.

Cui H, Tan YX, Österholm C, ..., Vlodavsky I, Li JP

Oncotarget 7 (26) 39486-39496 [2016-06-28; online 2016-10-26]

Affiliated researcher

PubMed DOI Crossref

Conformational diversity and enantioconvergence in potato epoxide hydrolase 1.

Bauer P, Carlsson ÅJ, Amrein BA, ..., Widersten M, Kamerlin SC

Org. Biomol. Chem. 14 (24) 5639-5651 [2016-06-28; online 2016-04-06]

Affiliated researcher

PubMed DOI Crossref

Cryptosporidium as a testbed for single cell genome characterization of unicellular eukaryotes.

Troell K, Hallström B, Divne AM, ..., Beser J, Bertilsson S

BMC Genomics 17 (-) 471 [2016-06-23; online 2016-06-23]

Affiliated researcher

PubMed DOI Crossref

Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations.

Wu C, de Miranda NF, Chen L, ..., Sander B, Pan-Hammarström Q

Oncotarget 7 (25) 38180-38190 [2016-06-21; online 2016-10-23]

Affiliated researcher

PubMed DOI Crossref

iGEMS: an integrated model for identification of alternative exon usage events.

Sood S, Szkop KJ, Nakhuda A, ..., Larsson O, Timmons JA

Nucleic Acids Res. 44 (11) e109 [2016-06-20; online 2016-04-19]

Affiliated researcher

PubMed DOI Crossref

Identification of Cancer Related Genes Using a Comprehensive Map of Human Gene Expression.

Torrente A, Lukk M, Xue V, ..., Rung J, Brazma A

PLoS ONE 11 (6) e0157484 [2016-06-20; online 2016-06-20]

Affiliated researcher

DOI Crossref

Mechanism-Guided Discovery of an Esterase Scaffold with Promiscuous Amidase Activity

Kürten C, Carlberg B, Syrén PO

Catalysts 6 (6) 90 [2016-06-18; online 2016-06-18]

Affiliated researcher

PubMed DOI Crossref

Overexpression of the scaffold WD40 protein WRAP53β enhances the repair of and cell survival from DNA double-strand breaks.

Rassoolzadeh H, Böhm S, Hedström E, ..., Henriksson S, Farnebo M

Cell Death Dis 7 (-) e2267 [2016-06-16; online 2016-06-16]

Affiliated researcher

PubMed DOI Crossref

Effects of Fluoxetine on Human Embryo Development.

Kaihola H, Yaldir FG, Hreinsson J, ..., Åkerud H, Sundström-Poromaa I

Front. Cell. Neurosci. 10 (-) 160 [2016-06-16; online 2016-06-16]

Affiliated researcher

PubMed DOI Crossref

Read-based phasing of related individuals.

Garg S, Martin M, Marschall T

Bioinformatics 32 (12) i234-i242 [2016-06-15; online 2016-06-17]

Affiliated researcher

PubMed DOI Crossref

Protein Z: A putative novel biomarker for early detection of ovarian cancer.

Russell MR, Walker MJ, Williamson AJ, ..., Jacobs I, Graham RL

Int. J. Cancer 138 (12) 2984-2992 [2016-06-15; online 2016-02-19]

Affiliated researcher

PubMed DOI Crossref

Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cells.

Pellegrini P, Dyczynski M, Sbrana FV, ..., Kharaziha P, De Milito A

Oncotarget 7 (24) 35703-35723 [2016-06-14; online 2016-06-02]

Affiliated researcher

PubMed DOI Crossref

The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia.

Papakonstantinou N, Ntoufa S, Chartomatsidou E, ..., Rosenquist R, Stamatopoulos K

Oncotarget 7 (24) 35946-35959 [2016-06-14; online 2016-05-19]

Affiliated researcher

PubMed DOI Crossref

Evolution and expression of the phosphodiesterase 6 genes unveils vertebrate novelty to control photosensitivity.

Lagman D, Franzén IE, Eggert J, Larhammar D, Abalo XM

BMC Evol Biol BMC Evolutionary Biology 16 (1) 124 [2016-06-13; online 2016-06-13]

Affiliated researcher

PubMed DOI Crossref

Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation.

Watanabe Y, Papoutsoglou P, Maturi V, ..., Heldin CH, Moustakas A

J. Biol. Chem. 291 (24) 12706-12723 [2016-06-10; online 2016-04-21]

Affiliated researcher

PubMed DOI Crossref

Reciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation.

Conti L, Renhorn J, Gabrielsson A, ..., Lindahl E, Elinder F

Sci Rep 6 (-) 27562 [2016-06-09; online 2016-06-09]

Affiliated researcher

PubMed DOI Crossref

YM155, a small molecule inhibitor of survivin expression, sensitizes cancer cells to hypericin-mediated photodynamic therapy.

Gyurászová K, Mikeš J, Halaburková A, Jendželovský R, Fedoročko P

Photochem. Photobiol. Sci. 15 (6) 812-821 [2016-06-08; online 2016-05-31]

Affiliated researcher

PubMed DOI Crossref

Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy.

Steshenko O, Andrade DM, Honigmann A, ..., Simons M, Eggeling C

Biophys. J. 110 (11) 2441-2450 [2016-06-07; online 2016-06-09]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Recommendations on e-infrastructures for next-generation sequencing.

Spjuth O, Bongcam-Rudloff E, Dahlberg J, ..., Vezzi F, Korpelainen E

Gigascience 5 (-) 26 [2016-06-07; online 2016-06-07]

Affiliated researcher

PubMed DOI Crossref

RNA sequencing-based analysis of gallbladder cancer reveals the importance of the liver X receptor and lipid metabolism in gallbladder cancer.

Zuo M, Rashid A, Wang Y, ..., Roa JC, Javle M

Oncotarget 7 (23) 35302-35312 [2016-06-07; online 2016-05-12]

Affiliated researcher

PubMed DOI Crossref

Promiscuity in the Enzymatic Catalysis of Phosphate and Sulfate Transfer.

Pabis A, Duarte F, Kamerlin SC

Biochemistry 55 (22) 3061-3081 [2016-06-07; online 2016-05-26]

Affiliated researcher

PubMed DOI Crossref

Early predictors of behavioural problems in pre-schoolers - a longitudinal study of constitutional and environmental main and interaction effects.

Agnafors S, Sydsjö G, Comasco E, ..., Oreland L, Svedin CG

BMC Pediatr 16 (-) 76 [2016-06-07; online 2016-06-07]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Integrating multiple immunogenetic data sources for feature extraction and mining somatic hypermutation patterns: the case of "towards analysis" in chronic lymphocytic leukaemia.

Kavakiotis I, Xochelli A, Agathangelidis A, ..., Vlahavas I, Chouvarda I

BMC Bioinformatics 17 Suppl 5 (-) 173 [2016-06-06; online 2016-06-06]

Affiliated researcher

PubMed DOI Crossref

Genetic Basis for Red Coloration in Birds.

Lopes RJ, Johnson JD, Toomey MB, ..., Corbo JC, Carneiro M

Curr. Biol. 26 (11) 1427-1434 [2016-06-06; online 2016-05-19]

Affiliated researcher

PubMed DOI Crossref

Feasibility of Multiple Examinations Using (68)Ga-Labelled Collagelin Analogues: Organ Distribution in Rat for Extrapolation to Human Organ and Whole-Body Radiation Dosimetry.

Velikyan I, Rosenström U, Bulenga TN, Eriksson O, Antoni G

Pharmaceuticals (Basel, Switzerland) 9 (2) - [2016-06-06; online 2016-06-06]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

A comparative evaluation of data-merging and meta-analysis methods for reconstructing gene-gene interactions.

Lagani V, Karozou AD, Gomez-Cabrero D, Silberberg G, Tsamardinos I

BMC Bioinformatics 17 Suppl 5 (-) 194 [2016-06-06; online 2016-06-06]

Affiliated researcher

PubMed DOI Crossref

GenFamClust: an accurate, synteny-aware and reliable homology inference algorithm.

Ali RH, Muhammad SA, Arvestad L

BMC Evol Biol BMC Evolutionary Biology 16 (1) 120 [2016-06-04; online 2016-06-04]

Affiliated researcher

PubMed DOI Crossref

Elevated levels of FN1 and CCL2 in bronchoalveolar lavage fluid from sarcoidosis patients.

Hamsten C, Wiklundh E, Grönlund H, ..., Grunewald J, Häggmark-Månberg A

Respir. Res. 17 (1) 69 [2016-06-04; online 2016-06-04]

Affiliated researcher

PubMed DOI Crossref

TT-seq maps the human transient transcriptome.

Schwalb B, Michel M, Zacher B, ..., Gagneur J, Cramer P

Science 352 (6290) 1225-1228 [2016-06-03; online 2016-06-04]

Affiliated researcher

PubMed DOI Crossref

Comprehensive Proteomic Study of the Antiproliferative Activity of a Polyphenol-Enriched Rosemary Extract on Colon Cancer Cells Using Nanoliquid Chromatography-Orbitrap MS/MS.

Valdés A, Artemenko KA, Bergquist J, García-Cañas V, Cifuentes A

J. Proteome Res. 15 (6) 1971-1985 [2016-06-03; online 2016-04-29]

Affiliated researcher

PubMed DOI Crossref

Prognostic impact of epigenetic classification in chronic lymphocytic leukemia: The case of subset #2.

Bhoi S, Ljungström V, Baliakas P, ..., Rosenquist R, Mansouri L

Epigenetics 11 (6) 449-455 [2016-06-02; online 2016-04-29]

Affiliated researcher

PubMed DOI Crossref

Organization and Regulation of Mitochondrial Protein Synthesis.

Ott M, Amunts A, Brown A

Annu. Rev. Biochem. 85 (1) 77-101 [2016-06-02; online 2016-01-18]

Affiliated researcher Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease.

Dumanski JP, Lambert JC, Rasi C, ..., Lind L, Forsberg LA

Am. J. Hum. Genet. 98 (6) 1208-1219 [2016-06-02; online 2016-05-23]

Affiliated researcher

PubMed DOI Crossref

c-Myb Enhances Breast Cancer Invasion and Metastasis through the Wnt/β-Catenin/Axin2 Pathway.

Li Y, Jin K, van Pelt GW, ..., Zhou F, Zhang L

Cancer Res. 76 (11) 3364-3375 [2016-06-01; online 2016-04-05]

Affiliated researcher

PubMed DOI Crossref

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease.

Orlando G, Law PJ, Palin K, ..., Aaltonen LA, Houlston RS

Hum. Mol. Genet. 25 (11) 2349-2359 [2016-06-01; online 2016-03-22]

Affiliated researcher

PubMed DOI Crossref

Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages.

Wallerius M, Wallmann T, Bartish M, ..., Andersson J, Rolny C

Cancer Res. 76 (11) 3166-3178 [2016-06-01; online 2016-04-06]

Affiliated researcher

PubMed DOI Crossref

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.

Scott RA, Freitag DF, Li L, ..., Wareham NJ, Waterworth DM

Sci Transl Med 8 (341) 341ra76 [2016-06-01; online 2016-06-03]

Affiliated researcher

PubMed DOI Crossref

Variation Interpretation Predictors: Principles, Types, Performance, and Choice.

Niroula A, Vihinen M

Hum. Mutat. 37 (6) 579-597 [2016-06-00; online 2016-04-15]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Tracing the Archaeal Origins of Eukaryotic Membrane-Trafficking System Building Blocks.

Klinger CM, Spang A, Dacks JB, Ettema TJ

Mol. Biol. Evol. 33 (6) 1528-1541 [2016-06-00; online 2016-02-17]

Affiliated researcher

PubMed DOI Crossref

Single Chain Antibodies as Tools to Study transforming growth factor-β-Regulated SMAD Proteins in Proximity Ligation-Based Pharmacological Screens.

Blokzijl A, Zieba A, Hust M, ..., Dübel S, Landegren U

Mol. Cell Proteomics 15 (6) 1848-1856 [2016-06-00; online 2016-02-29]

Affiliated researcher

PubMed DOI Crossref

Identification of Multiple Loci Associated with Social Parasitism in Honeybees.

Wallberg A, Pirk CW, Allsopp MH, Webster MT

PLoS Genet 12 (6) e1006097 [2016-06-00; online 2016-06-09]

Affiliated researcher

PubMed DOI Crossref

High density of REC8 constrains sister chromatid axes and prevents illegitimate synaptonemal complex formation.

Agostinho A, Manneberg O, van Schendel R, ..., Brismar H, Höög C

EMBO Rep. 17 (6) 901-913 [2016-06-00; online 2016-05-11]

Affiliated researcher

PubMed DOI Crossref

Genetic variants associated with antithyroid drug-induced agranulocytosis: a genome-wide association study in a European population

Hallberg P, Eriksson N, Ibañez L, ..., Magnusson PKE, Wadelius M

The Lancet Diabetes & Endocrinology 4 (6) 507-516 [2016-06-00; online 2016-06-00]

Affiliated researcher

PubMed DOI Crossref

GPR44 is a pancreatic protein restricted to the human beta cell.

Hellström-Lindahl E, Danielsson A, Ponten F, ..., Johansson L, Eriksson O

Acta Diabetol 53 (3) 413-421 [2016-06-00; online 2015-10-14]

Affiliated researcher Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation.

Chlamydas S, Holz H, Samata M, ..., Steinmetz LM, Akhtar A

Nat. Struct. Mol. Biol. 23 (6) 580-589 [2016-06-00; online 2016-05-16]

Affiliated researcher SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Epigenome-wide DNA methylation patterns associated with fatigue in primary Sjögren's syndrome.

Brække Norheim K, Imgenberg-Kreuz J, Jonsdottir K, ..., Nordmark G, Omdal R

Rheumatology (Oxford) 55 (6) 1074-1082 [2016-06-00; online 2016-03-10]

Affiliated researcher

PubMed DOI Crossref

Disruptive selection without genome-wide evolution across a migratory divide.

von Rönn JA, Shafer AB, Wolf JB

Mol. Ecol. 25 (11) 2529-2541 [2016-06-00; online 2016-03-09]

Affiliated researcher

PubMed DOI Crossref

Detection of Biomarkers with Solid-Phase Proximity Ligation Assay in Patients with Colorectal Cancer.

Ghanipour L, Darmanis S, Landegren U, ..., Påhlman L, Birgisson H

Transl Oncol 9 (3) 251-255 [2016-06-00; online 2016-06-09]

Affiliated researcher

PubMed DOI Crossref

Decreased fracture rate, pharmacogenetics and BMD response in 79 Swedish children with osteogenesis imperfecta types I, III and IV treated with Pamidronate.

Lindahl K, Kindmark A, Rubin CJ, ..., Ljunggren Ö, Åström E

Bone 87 (-) 11-18 [2016-06-00; online 2016-03-05]

Affiliated researcher

PubMed DOI Crossref

DNA damage signalling barrier, oxidative stress and treatment-relevant DNA repair factor alterations during progression of human prostate cancer.

Kurfurstova D, Bartkova J, Vrtel R, ..., Bouchal J, Bartek J

Mol Oncol 10 (6) 879-894 [2016-06-00; online 2016-03-03]

Affiliated researcher

PubMed DOI Crossref

An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection.

Müller AA, Dolowschiak T, Sellin ME, ..., LeibundGut-Landmann S, Hardt WD

PLoS Pathog 12 (6) e1005723 [2016-06-00; online 2016-06-24]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Allele-specific transcription factor binding in liver and cervix cells unveils many likely drivers of GWAS signals.

Cavalli M, Pan G, Nord H, ..., Wallerman O, Wadelius C

Genomics 107 (6) 248-254 [2016-06-00; online 2016-04-26]

Affiliated researcher

PubMed DOI Crossref

Affinity proteomics discovers decreased levels of AMFR in plasma from Osteoporosis patients.

Qundos U, Drobin K, Mattsson C, ..., Michaëlsson K, Schwenk JM

Proteomics Clin Appl 10 (6) 681-690 [2016-06-00; online 2015-04-21]

Affiliated researcher

PubMed DOI Crossref

A Complete Overhaul of the Electron Energy-Loss Spectroscopy and X-Ray Absorption Spectroscopy Database: eelsdb.eu.

Ewels P, Sikora T, Serin V, Ewels CP, Lajaunie L

Microsc. Microanal. 22 (3) 717-724 [2016-06-00; online 2016-02-22]

Affiliated researcher

PubMed DOI Crossref

Variants within the SP110 nuclear body protein modify risk of canine degenerative myelopathy.

Ivansson EL, Megquier K, Kozyrev SV, ..., Coates JR, Lindblad-Toh K

Proc. Natl. Acad. Sci. U.S.A. 113 (22) E3091-E3100 [2016-05-31; online 2016-05-16]

Affiliated researcher

PubMed DOI Crossref

Genome-culture coevolution promotes rapid divergence of killer whale ecotypes.

Foote AD, Vijay N, Ávila-Arcos MC, ..., Gilbert MT, Wolf JB

Nat Commun 7 (-) 11693 [2016-05-31; online 2016-05-31]

Affiliated researcher

PubMed DOI Crossref

Cross-talk between the Tissue Factor/coagulation factor VIIa complex and the tyrosine kinase receptor EphA2 in cancer.

Eriksson O, Thulin Å, Asplund A, ..., Navani S, Siegbahn A

BMC Cancer 16 (-) 341 [2016-05-31; online 2016-05-31]

Affiliated researcher

PubMed DOI Crossref

The POU/Oct Transcription Factor Pdm1/nub Is Necessary for a Beneficial Gut Microbiota and Normal Lifespan of Drosophila.

Dantoft W, Lundin D, Esfahani SS, Engström Y

J Innate Immun 8 (4) 412-426 [2016-05-28; online 2016-05-28]

Affiliated researcher

PubMed DOI Crossref

Thermotolerant yeasts selected by adaptive evolution express heat stress response at 30 °C.

Caspeta L, Chen Y, Nielsen J

Sci Rep 6 (-) 27003 [2016-05-27; online 2016-05-27]

Affiliated researcher

PubMed DOI Crossref

The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling.

Rorsman C, Tsioumpekou M, Heldin CH, Lennartsson J

J. Biol. Chem. 291 (22) 11608-11618 [2016-05-27; online 2016-04-05]

Affiliated researcher

PubMed DOI Crossref

Heparin interactions with apoA1 and SAA in inflammation-associated HDL.

Digre A, Nan J, Frank M, Li JP

Biochem. Biophys. Res. Commun. 474 (2) 309-314 [2016-05-27; online 2016-04-20]

Affiliated researcher

PubMed DOI Crossref

Production of fatty acid-derived oleochemicals and biofuels by synthetic yeast cell factories.

Zhou YJ, Buijs NA, Zhu Z, ..., Siewers V, Nielsen J

Nat Commun 7 (-) 11709 [2016-05-25; online 2016-05-25]

Affiliated researcher

PubMed DOI Crossref

New technologies for DNA analysis--a review of the READNA Project.

McGinn S, Bauer D, Brefort T, ..., Willcocks JP, Gut IG

N Biotechnol 33 (3) 311-330 [2016-05-25; online 2015-10-26]

Affiliated researcher

PubMed DOI Crossref

Subnanometer Structure of an Asymmetric Model Membrane: Interleaflet Coupling Influences Domain Properties.

Heberle FA, Marquardt D, Doktorova M, ..., London E, Pabst G

Langmuir 32 (20) 5195-5200 [2016-05-24; online 2016-05-16]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

A surprisingly poor correlation between in vitro and in vivo testing of biomaterials for bone regeneration: results of a multicentre analysis.

Hulsart-Billström G, Dawson JI, Hofmann S, ..., Larsson S, Oreffo RO

Eur Cell Mater 31 (-) 312-322 [2016-05-24; online 2016-05-24]

Affiliated researcher

PubMed DOI Crossref

Mitochondrial Evolution: Going, Going, Gone.

Burki F

Curr. Biol. 26 (10) R410-R412 [2016-05-23; online 2016-05-25]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Conditional Disease Development extracted from Longitudinal Health Care Cohort Data using Layered Network Construction.

Kannan V, Swartz F, Kiani NA, ..., Alexanderson K, Tegnèr J

Sci Rep 6 (-) 26170 [2016-05-23; online 2016-05-23]

Affiliated researcher

PubMed DOI Crossref

The mitogenome of a 35,000-year-old Homo sapiens from Europe supports a Palaeolithic back-migration to Africa.

Hervella M, Svensson EM, Alberdi A, ..., Netea MG, de-la-Rua C

Sci Rep 6 (-) 25501 [2016-05-19; online 2016-05-19]

Affiliated researcher

PubMed DOI Crossref

Metagenomic Analysis of the Indian Ocean Picocyanobacterial Community: Structure, Potential Function and Evolution.

Díez B, Nylander JA, Ininbergs K, ..., Rusch DB, Bergman B

PLoS ONE 11 (5) e0155757 [2016-05-19; online 2016-05-19]

Affiliated researcher

PubMed DOI Crossref

Minimal selective concentrations of tetracycline in complex aquatic bacterial biofilms.

Lundström SV, Östman M, Bengtsson-Palme J, ..., Flach CF, Larsson DGJ

Sci. Total Environ. 553 (-) 587-595 [2016-05-15; online 2016-03-22]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Inclusion of dyad-repeat pattern improves topology prediction of transmembrane β-barrel proteins.

Hayat S, Peters C, Shu N, Tsirigos KD, Elofsson A

Bioinformatics 32 (10) 1571-1573 [2016-05-15; online 2016-01-21]

Affiliated researcher

PubMed DOI Crossref

B Cell Anergy Modulated by TLR1/2 and the miR-17∼92 Cluster Underlies the Indolent Clinical Course of Chronic Lymphocytic Leukemia Stereotyped Subset #4.

Ntoufa S, Papakonstantinou N, Apollonio B, ..., Ghia P, Stamatopoulos K

J. Immunol. 196 (10) 4410-4417 [2016-05-15; online 2016-04-08]

Affiliated researcher

PubMed DOI Crossref

Dynamic alterations of bone marrow cytokine landscape of myelodysplastic syndromes patients treated with 5-azacytidine.

Moudra A, Hubackova S, Machalova V, ..., Hodny Z, Jonasova A

Oncoimmunology 5 (10) e1183860 [2016-05-13; online 2016-05-13]

Affiliated researcher

PubMed DOI Crossref

Diversity of Pico- to Mesoplankton along the 2000 km Salinity Gradient of the Baltic Sea.

Hu YO, Karlson B, Charvet S, Andersson AF

Front Microbiol 7 (-) 679 [2016-05-12; online 2016-05-12]

Affiliated researcher

PubMed DOI Crossref

Significant association and synergistic adverse prognostic effect of podocalyxin-like protein and epidermal growth factor receptor expression in colorectal cancer.

Larsson AH, Lehn S, Wangefjord S, ..., Birgisson H, Jirström K

J Transl Med 14 (1) 128 [2016-05-10; online 2016-05-10]

Affiliated researcher

PubMed DOI Crossref

A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs.

Raffan E, Dennis RJ, O'Donovan CJ, ..., Yeo GS, O'Rahilly S

Cell Metab. 23 (5) 893-900 [2016-05-10; online 2016-05-03]

Affiliated researcher

PubMed DOI Crossref

Hyaluronic Acid Hydrogels Formed in Situ by Transglutaminase-Catalyzed Reaction.

Ranga A, Lutolf MP, Hilborn J, Ossipov DA

Biomacromolecules 17 (5) 1553-1560 [2016-05-09; online 2016-04-08]

Affiliated researcher

PubMed DOI Crossref

The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons.

García-Martínez J, Delgado-Ramos L, Ayala G, ..., Chávez S, Pérez-Ortín JE

Nucleic Acids Res. 44 (8) 3643-3658 [2016-05-05; online 2015-12-29]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Identification of a Non-Pentapeptide Region Associated with Rapid Mycobacterial Evolution.

Warholm P, Light S

PLoS ONE 11 (5) e0154059 [2016-05-05; online 2016-05-05]

Affiliated researcher

PubMed DOI Crossref

Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis.

Valenta T, Degirmenci B, Moor AE, ..., Aguet M, Basler K

Cell Reports 15 (5) 911-918 [2016-05-03; online 2016-04-21]

Affiliated researcher

PubMed DOI Crossref

The genetic basis for ecological adaptation of the Atlantic herring revealed by genome sequencing.

Martinez Barrio A, Lamichhaney S, Fan G, ..., Xu X, Andersson L

Elife 5 (-) - [2016-05-03; online 2016-05-03]

Affiliated researcher

PubMed DOI Crossref

Epigenetic silencing of miR-26A1 in chronic lymphocytic leukemia and mantle cell lymphoma: Impact on EZH2 expression.

Kopparapu PK, Bhoi S, Mansouri L, ..., Rosenquist R, Kanduri M

Epigenetics 11 (5) 335-343 [2016-05-03; online 2016-04-06]

Affiliated researcher

PubMed DOI Crossref

TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology.

Morikawa M, Derynck R, Miyazono K

Cold Spring Harbor Perspectives in Biology 8 (5) - [2016-05-02; online 2016-05-02]

Affiliated researcher

PubMed DOI Crossref

Investigating the Combinatory Effects of Biological Networks on Gene Co-expression.

Zhang C, Lee S, Mardinoglu A, Hua Q

Front. Physiol. 7 (-) 160 [2016-05-02; online 2016-05-02]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Vitamin D Induces Global Gene Transcription in Human Corneal Epithelial Cells: Implications for Corneal Inflammation.

Reins RY, Mesmar F, Williams C, McDermott AM

Invest. Ophthalmol. Vis. Sci. 57 (6) 2689-2698 [2016-05-01; online 2016-05-20]

Affiliated researcher

PubMed DOI Crossref

ProQ2: estimation of model accuracy implemented in Rosetta.

Uziela K, Wallner B

Bioinformatics 32 (9) 1411-1413 [2016-05-01; online 2016-01-05]

Affiliated researcher

PubMed DOI Crossref

nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs.

Gandin V, Masvidal L, Hulea L, ..., Larsson O, Topisirovic I

Genome Res. 26 (5) 636-648 [2016-05-00; online 2016-03-16]

Affiliated researcher

PubMed DOI Crossref

Utilizing the Dog Genome in the Search for Novel Candidate Genes Involved in Glioma Development-Genome Wide Association Mapping followed by Targeted Massive Parallel Sequencing Identifies a Strongly Associated Locus.

Truvé K, Dickinson P, Xiong A, ..., Bannasch D, Lindblad-Toh K

PLoS Genet 12 (5) e1006000 [2016-05-00; online 2016-05-12]

Affiliated researcher

PubMed DOI Crossref

Standardized benchmarking in the quest for orthologs.

Altenhoff AM, Boeckmann B, Capella-Gutierrez S, ..., Sonnhammer E, Dessimoz C

Nat. Methods 13 (5) 425-430 [2016-05-00; online 2016-04-04]

Affiliated researcher

PubMed DOI Crossref

Selection of optimal chelator improves the contrast of GRPR imaging using bombesin analogue RM26.

Mitran B, Varasteh Z, Selvaraju RK, ..., Rosenström U, Orlova A

Int. J. Oncol. 48 (5) 2124-2134 [2016-05-00; online 2016-03-09]

Affiliated researcher

PubMed DOI Crossref

Rpb1 foot mutations demonstrate a major role of Rpb4 in mRNA stability during stress situations in yeast.

Garrido-Godino AI, García-López MC, García-Martínez J, ..., Pérez-Ortín JE, Navarro F

Biochim. Biophys. Acta 1859 (5) 731-743 [2016-05-00; online 2016-03-18]

Affiliated researcher SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Potential of Synechocystis PCC 6803 as a novel cyanobacterial chassis for heterologous expression of enzymes in the trans-resveratrol biosynthetic pathway.

Tantong S, Incharoensakdi A, Sirikantaramas S, Lindblad P

Protein Expr. Purif. 121 (-) 163-168 [2016-05-00; online 2016-02-01]

Affiliated researcher

PubMed DOI Crossref

Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model.

Spiegelberg D, Mortensen AC, Selvaraju RK, ..., Stenerlöw B, Nestor M

Eur. J. Nucl. Med. Mol. Imaging 43 (5) 974-982 [2016-05-00; online 2015-12-01]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Microbial metagenomes from three aquifers in the Fennoscandian shield terrestrial deep biosphere reveal metabolic partitioning among populations.

Wu X, Holmfeldt K, Hubalek V, ..., Bertilsson S, Dopson M

ISME J 10 (5) 1192-1203 [2016-05-00; online 2015-10-20]

Affiliated researcher

DOI Crossref

Metaxa2 Diversity Tools: Easing microbial community analysis with Metaxa2

Bengtsson-Palme J, Thorell K, Wurzbacher C, Sjöling Å, Nilsson RH

Ecological Informatics 33 (-) 45-50 [2016-05-00; online 2016-05-00]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Increased diversification rates follow shifts to bisexuality in liverworts.

Laenen B, Machac A, Gradstein SR, ..., Shaw AJ, Vanderpoorten A

New Phytol. 210 (3) 1121-1129 [2016-05-00; online 2016-02-01]

Affiliated researcher

PubMed DOI Crossref

In vitro and ex vivo vanadium antitumor activity in (TGF-β)-induced EMT. Synergistic activity with carboplatin and correlation with tumor metastasis in cancer patients.

Petanidis S, Kioseoglou E, Domvri K, ..., Moustakas A, Salifoglou A

Int. J. Biochem. Cell Biol. 74 (-) 121-134 [2016-05-00; online 2016-02-23]

Affiliated researcher

PubMed DOI Crossref

Genome-Wide Analysis Identifies Germ-Line Risk Factors Associated with Canine Mammary Tumours.

Melin M, Rivera P, Arendt M, ..., Rönnberg H, Lindblad-Toh K

PLoS Genet 12 (5) e1006029 [2016-05-00; online 2016-05-09]

Affiliated researcher

PubMed DOI Crossref

Genetic loci on chromosome 5 are associated with circulating levels of interleukin-5 and eosinophil count in a European population with high risk for cardiovascular disease.

McLeod O, Silveira A, Valdes-Marquez E, ..., Strawbridge RJ, IMPROVE Study Group

Cytokine 81 (-) 1-9 [2016-05-00; online 2016-01-25]

Affiliated researcher

PubMed DOI Crossref

Gap Filling as Exact Path Length Problem.

Salmela L, Sahlin K, Mäkinen V, Tomescu AI

J. Comput. Biol. 23 (5) 347-361 [2016-05-00; online 2016-03-09]

Affiliated researcher Kristoffer Sahlin SciLifeLab Fellow

PubMed DOI Crossref

Functionalized silk assembled from a recombinant spider silk fusion protein (Z-4RepCT) produced in the methylotrophic yeast Pichia pastoris.

Jansson R, Lau CH, Ishida T, ..., Sandgren M, Hedhammar M

Biotechnol J 11 (5) 687-699 [2016-05-00; online 2016-03-04]

Affiliated researcher

PubMed DOI Crossref

Distinct temporal changes in host cell lncRNA expression during the course of an adenovirus infection.

Zhao H, Chen M, Lind SB, Pettersson U

Virology 492 (-) 242-250 [2016-05-00; online 2016-03-21]

Affiliated researcher

PubMed DOI Crossref

Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States.

Rudolph KL, Schmitt BM, Villar D, ..., Kutter C, Odom DT

PLoS Genet 12 (5) e1006024 [2016-05-00; online 2016-05-11]

Affiliated researcher Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Biotin and Thiamine Responsive Basal Ganglia Disease--A vital differential diagnosis in infants with severe encephalopathy.

Ygberg S, Naess K, Eriksson M, ..., Wedell A, Wickström R

Eur. J. Paediatr. Neurol. 20 (3) 457-461 [2016-05-00; online 2016-02-04]

Affiliated researcher

PubMed DOI Crossref

Antigen arrays for profiling autoantibody repertoires.

Ayoglu B, Schwenk JM, Nilsson P

Bioanalysis 8 (10) 1105-1126 [2016-05-00; online 2016-04-21]

Affiliated researcher

PubMed DOI Crossref

Analysis of Mitochondrial DNA from a Burned, Ninhydrin-Treated Paper Towel.

Buś MM, Nilsson M, Allen M

J. Forensic Sci. 61 (3) 828-832 [2016-05-00; online 2016-02-25]

Affiliated researcher

PubMed DOI Crossref

Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression.

Cavalli M, Pan G, Nord H, ..., Lindblad Toh K, Wadelius C

Hum. Genet. 135 (5) 485-497 [2016-05-00; online 2016-03-18]

Affiliated researcher

PubMed DOI Crossref

A Systematic Characterization of Aquaporin-9 Expression in Human Normal and Pathological Tissues.

Lindskog C, Asplund A, Catrina A, Nielsen S, Rützler M

J. Histochem. Cytochem. 64 (5) 287-300 [2016-05-00; online 2016-03-29]

Affiliated researcher

PubMed DOI Crossref

An Improved microRNA Annotation of the Canine Genome.

Penso-Dolfin L, Swofford R, Johnson J, ..., Moxon S, Di Palma F

PLoS ONE 11 (4) e0153453 [2016-04-27; online 2016-04-27]

Affiliated researcher

PubMed DOI Crossref

Systems biology analysis of hepatitis C virus infection reveals the role of copy number increases in regions of chromosome 1q in hepatocellular carcinoma metabolism.

Elsemman IE, Mardinoglu A, Shoaie S, Soliman TH, Nielsen J

Mol Biosyst 12 (5) 1496-1506 [2016-04-26; online 2016-04-05]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model.

de Boeck M, Cui C, Mulder AA, ..., Ikeno S, Ten Dijke P

Sci Rep 6 (-) 24968 [2016-04-26; online 2016-04-26]

Affiliated researcher

PubMed DOI Crossref

Elevated Levels of SOX10 in Serum from Vitiligo and Melanoma Patients, Analyzed by Proximity Ligation Assay.

Blokzijl A, Chen LE, Gustafsdottir SM, ..., Kamali-Moghaddam M, Hedstrand H

PLoS ONE 11 (4) e0154214 [2016-04-25; online 2016-04-25]

Affiliated researcher

PubMed DOI Crossref

Absolute quantification reveals the stable transmission of a high copy number variant linked to autoinflammatory disease.

Olsson M, Kierczak M, Karlsson Å, ..., Lindblad-Toh K, Meadows JR

BMC Genomics 17 (-) 299 [2016-04-23; online 2016-04-23]

Affiliated researcher

DOI Crossref

Effects of warming on a Mediterranean phytoplankton community

Pulina S, Brutemark A, Suikkanen S, ..., Sechi N, Lugliè A

Web Ecol. 16 (1) 89-92 [2016-04-22; online 2016-04-22]

Affiliated researcher

PubMed DOI Crossref

Minimizing antibody cross-reactivity in multiplex detection of biomarkers in paper-based point-of-care assays.

Dias JT, Lama L, Gantelius J, Andersson-Svahn H

Nanoscale 8 (15) 8195-8201 [2016-04-21; online 2016-04-01]

Affiliated researcher

PubMed DOI Crossref

Mechanism for excitation-dependent photoluminescence from graphene quantum dots and other graphene oxide derivates: consensus, debates and challenges.

Gan Z, Xu H, Hao Y

Nanoscale 8 (15) 7794-7807 [2016-04-21; online 2016-04-01]

Affiliated researcher

PubMed DOI Crossref

A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors.

Ruiz S, Mayor-Ruiz C, Lafarga V, ..., Ortega S, Fernandez-Capetillo O

Mol. Cell 62 (2) 307-313 [2016-04-21; online 2016-04-07]

Affiliated researcher

PubMed DOI Crossref

Proficient Detection of Multi-Drug-Resistant Mycobacterium tuberculosis by Padlock Probes and Lateral Flow Nucleic Acid Biosensors.

Pavankumar AR, Engström A, Liu J, Herthnek D, Nilsson M

Anal. Chem. 88 (8) 4277-4284 [2016-04-19; online 2016-04-04]

Affiliated researcher

PubMed DOI Crossref

Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma.

Wang N, Kjellin H, Sofiadis A, ..., Lehtiö J, Larsson C

Oncotarget 7 (16) 21332-21346 [2016-04-19; online 2016-02-13]

Affiliated researcher

PubMed DOI Crossref

Improved topology prediction using the terminal hydrophobic helices rule.

Peters C, Tsirigos KD, Shu N, Elofsson A

Bioinformatics 32 (8) 1158-1162 [2016-04-15; online 2015-12-07]

Affiliated researcher

PubMed DOI Crossref

Hypoxic Signaling and the Cellular Redox Tumor Environment Determine Sensitivity to MTH1 Inhibition.

Bräutigam L, Pudelko L, Jemth AS, ..., Stenmark P, Helleday T

Cancer Res. 76 (8) 2366-2375 [2016-04-15; online 2016-02-09]

Affiliated researcher

PubMed DOI Crossref

Cytosolic splice isoform of Hsp70 nucleotide exchange factor Fes1 is required for the degradation of misfolded proteins in yeast.

Gowda NK, Kaimal JM, Masser AE, ..., Friedländer MR, Andréasson C

Mol. Biol. Cell 27 (8) 1210-1219 [2016-04-15; online 2016-02-24]

Affiliated researcher Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Approaches to augment CAR T-cell therapy by targeting the apoptotic machinery.

Karlsson H

Biochem. Soc. Trans. 44 (2) 371-376 [2016-04-15; online 2016-04-14]

Affiliated researcher

PubMed DOI Crossref

An Immunogenetic Signature of Ongoing Antigen Interactions in Splenic Marginal Zone Lymphoma Expressing IGHV1-2*04 Receptors.

Bikos V, Karypidou M, Stalika E, ..., Hadzidimitriou A, Stamatopoulos K

Clin. Cancer Res. 22 (8) 2032-2040 [2016-04-15; online 2015-12-08]

Affiliated researcher

PubMed DOI Crossref

A New Way Forward in Cancer Drug Discovery: Inhibiting the SWI/SNF Chromatin Remodelling Complex.

Zinzalla G

Chembiochem 17 (8) 677-682 [2016-04-15; online 2016-01-28]

Affiliated researcher

PubMed DOI Crossref

RING finger protein 31 promotes p53 degradation in breast cancer cells.

Zhu J, Zhao C, Zhuang T, ..., Strömblad S, Dahlman-Wright K

Oncogene 35 (15) 1955-1964 [2016-04-14; online 2015-07-06]

Affiliated researcher

PubMed DOI Crossref

Heparan Sulfate: Biosynthesis, Structure, and Function.

Li JP, Kusche-Gullberg M

Int Rev Cell Mol Biol 325 (-) 215-273 [2016-04-13; online 2016-04-13]

Affiliated researcher

PubMed DOI Crossref

Immunostimulatory AdCD40L gene therapy combined with low-dose cyclophosphamide in metastatic melanoma patients.

Loskog A, Maleka A, Mangsbo S, ..., Tötterman TH, Ullenhag G

Br. J. Cancer 114 (8) 872-880 [2016-04-12; online 2016-03-31]

Affiliated researcher

PubMed DOI Crossref

Stability of the Encoding Plasmids and Surface Expression of CS6 Differs in Enterotoxigenic Escherichia coli (ETEC) Encoding Different Heat-Stable (ST) Enterotoxins (STh and STp).

Tobias J, Von Mentzer A, Loayza Frykberg P, ..., Sjöling Å, Svennerholm AM

PLoS ONE 11 (4) e0152899 [2016-04-07; online 2016-04-07]

Astrid von Mentzer DDLS Fellow

PubMed DOI Crossref

Microchip Screening Platform for Single Cell Assessment of NK Cell Cytotoxicity.

Guldevall K, Brandt L, Forslund E, ..., Uhlin M, Önfelt B

Front Immunol 7 (-) 119 [2016-04-05; online 2016-04-05]

Affiliated researcher

PubMed DOI Crossref

mTORC1 and CK2 coordinate ternary and eIF4F complex assembly.

Gandin V, Masvidal L, Cargnello M, ..., Larsson O, Topisirovic I

Nat Commun 7 (-) 11127 [2016-04-04; online 2016-04-04]

Affiliated researcher

PubMed DOI Crossref

Transcriptomics resources of human tissues and organs.

Uhlén M, Hallström BM, Lindskog C, ..., Pontén F, Nielsen J

Mol Syst Biol 12 (4) 862 [2016-04-04; online 2016-04-04]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Label-Free Fluctuation Spectroscopy Based on Coherent Anti-Stokes Raman Scattering from Bulk Water Molecules.

Rabasovic MD, Sisamakis E, Wennmalm S, Widengren J

Chemphyschem 17 (7) 1025-1033 [2016-04-04; online 2016-02-11]

Affiliated researcher

PubMed DOI Crossref

3D Bioprinting of Tissue/Organ Models.

Pati F, Gantelius J, Svahn HA

Angew. Chem. Int. Ed. Engl. 55 (15) 4650-4665 [2016-04-04; online 2016-02-19]

Affiliated researcher

PubMed DOI Crossref

Streptavidin-modified monodispersed magnetic poly(2-hydroxyethyl methacrylate) microspheres as solid support in DNA-based molecular protocols.

Salih T, Ahlford A, Nilsson M, Plichta Z, Horák D

Mater Sci Eng C Mater Biol Appl 61 (-) 362-367 [2016-04-01; online 2015-12-30]

Affiliated researcher

PubMed DOI Crossref

Signals and Receptors.

Heldin CH, Lu B, Evans R, Gutkind JS

Cold Spring Harbor Perspectives in Biology 8 (4) a005900 [2016-04-01; online 2016-04-01]

Affiliated researcher

PubMed DOI Crossref

Na+-K+-ATPase, a new class of plasma membrane receptors.

Aperia A, Akkuratov EE, Fontana JM, Brismar H

Am. J. Physiol., Cell Physiol. 310 (7) C491-C495 [2016-04-01; online 2016-01-20]

Affiliated researcher

PubMed DOI Crossref

Genome-wide association and Mendelian randomization study of NT-proBNP in patients with acute coronary syndrome.

Johansson Å, Eriksson N, Lindholm D, ..., Wallentin L, PLATO Investigators

Hum. Mol. Genet. 25 (7) 1447-1456 [2016-04-01; online 2016-01-21]

Affiliated researcher

PubMed DOI Crossref

CopyNumber450kCancer: baseline correction for accurate copy number calling from the 450k methylation array.

Marzouka NA, Nordlund J, Bäcklin CL, ..., Syvänen AC, Carlsson Almlöf J

Bioinformatics 32 (7) 1080-1082 [2016-04-01; online 2015-11-09]

Affiliated researcher

PubMed DOI Crossref

USP7 is a SUMO deubiquitinase essential for DNA replication.

Lecona E, Rodriguez-Acebes S, Specks J, ..., Mendez J, Fernandez-Capetillo O

Nat. Struct. Mol. Biol. 23 (4) 270-277 [2016-04-00; online 2016-03-07]

Affiliated researcher

PubMed DOI Crossref

The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons.

Braasch I, Gehrke AR, Smith JJ, ..., Lindblad-Toh K, Postlethwait JH

Nat. Genet. 48 (4) 427-437 [2016-04-00; online 2016-03-07]

Affiliated researcher

DOI Crossref

The involvement of heparan sulfate proteoglycans in stem cell differentiation and in malignant glioma

Kundu S, Xiong A, Forsberg-Nilsson K

Eur. Phys. J. Plus 131 (4) - [2016-04-00; online 2016-04-08]

Affiliated researcher

PubMed DOI Crossref

The inflammatory inception of gallbladder cancer.

Espinoza JA, Bizama C, García P, ..., Koshiol J, Roa JC

Biochim. Biophys. Acta 1865 (2) 245-254 [2016-04-00; online 2016-03-12]

Affiliated researcher

PubMed DOI Crossref

The heterogeneity of human CD127(+) innate lymphoid cells revealed by single-cell RNA sequencing.

Björklund ÅK, Forkel M, Picelli S, ..., Sandberg R, Mjösberg J

Nat. Immunol. 17 (4) 451-460 [2016-04-00; online 2016-02-15]

Affiliated researcher

PubMed DOI Crossref

Sleep duration, depression, and oxytocinergic genotype influence prepulse inhibition of the startle reflex in postpartum women.

Comasco E, Gulinello M, Hellgren C, ..., Sylven S, Sundström-Poromaa I

Eur Neuropsychopharmacol 26 (4) 767-776 [2016-04-00; online 2016-01-22]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Role of ribosomal protein mutations in tumor development (Review).

Goudarzi KM, Lindström MS

Int. J. Oncol. 48 (4) 1313-1324 [2016-04-00; online 2016-02-09]

Affiliated researcher

PubMed DOI Crossref

Promiscuity and electrostatic flexibility in the alkaline phosphatase superfamily.

Pabis A, Kamerlin SC

Curr. Opin. Struct. Biol. 37 (-) 14-21 [2016-04-00; online 2015-12-21]

Affiliated researcher

PubMed DOI Crossref

Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?

Baliakas P, Mattsson M, Stamatopoulos K, Rosenquist R

J. Intern. Med. 279 (4) 347-357 [2016-04-00; online 2015-12-28]

Affiliated researcher

PubMed DOI Crossref

Precaution for volume conduction in rodent cortical electroencephalography using high-density polyimide-based microelectrode arrays on the skull.

Stienen PJ, Venzi M, Poppendieck W, Hoffmann KP, Åberg E

J. Neurophysiol. 115 (4) 1970-1977 [2016-04-00; online 2016-02-10]

Affiliated researcher

PubMed DOI Crossref

One CNV Discordance in NRXN1 Observed Upon Genome-wide Screening in 38 Pairs of Adult Healthy Monozygotic Twins.

Magnusson PK, Lee D, Chen X, ..., Feuk L, Pawitan Y

Twin Res Hum Genet 19 (2) 97-103 [2016-04-00; online 2016-02-22]

Affiliated researcher

PubMed DOI Crossref

Novel mode of inhibition by D-tagatose 6-phosphate through a Heyns rearrangement in the active site of transaldolase B variants.

Stellmacher L, Sandalova T, Schneider S, ..., Sprenger GA, Samland AK

Acta Crystallogr D Struct Biol 72 (Pt 4) 467-476 [2016-04-00; online 2016-03-24]

Affiliated researcher

PubMed DOI Crossref

NgR1: A Tunable Sensor Regulating Memory Formation, Synaptic, and Dendritic Plasticity.

Karlsson TE, Smedfors G, Brodin AT, ..., Brené S, Olson L

Cereb. Cortex 26 (4) 1804-1817 [2016-04-00; online 2016-02-02]

Affiliated researcher

PubMed DOI Crossref

Neuroproteomic profiling of human body fluids.

Häggmark A, Schwenk JM, Nilsson P

Proteomics Clin Appl 10 (4) 485-502 [2016-04-00; online 2015-10-12]

Affiliated researcher

PubMed DOI Crossref

Multiplexed protein profiling by sequential affinity capture.

Ayoglu B, Birgersson E, Mezger A, ..., Nilsson P, Schwenk JM

Proteomics 16 (8) 1251-1256 [2016-04-00; online 2016-03-31]

Affiliated researcher

PubMed DOI Crossref

Motor neuron-like NSC-34 cells as a new model for the study of vitamin D metabolism in the brain.

Almokhtar M, Wikvall K, Ubhayasekera SJKA, Bergquist J, Norlin M

J. Steroid Biochem. Mol. Biol. 158 (-) 178-188 [2016-04-00; online 2015-12-15]

Affiliated researcher

PubMed DOI Crossref

Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach.

Vildhede A, Mateus A, Khan EK, ..., Artursson P, Kjellsson MC

Drug Metab. Dispos. 44 (4) 505-516 [2016-04-00; online 2016-02-03]

Affiliated researcher

PubMed DOI Crossref

Introgression maintains the genetic integrity of the mating-type determining chromosome of the fungus Neurospora tetrasperma.

Corcoran P, Anderson JL, Jacobson DJ, ..., Lascoux M, Johannesson H

Genome Res. 26 (4) 486-498 [2016-04-00; online 2016-02-18]

Affiliated researcher

PubMed DOI Crossref

In Vivo Cytochrome P450 3A Isoenzyme Activity and Pharmacokinetics of Imatinib in Relation to Therapeutic Outcome in Patients With Chronic Myeloid Leukemia.

Skoglund K, Richter J, Olsson-Strömberg U, ..., Lotfi K, Gréen H

Ther Drug Monit 38 (2) 230-238 [2016-04-00; online 2015-12-24]

Affiliated researcher

PubMed DOI Crossref

Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening.

Engen K, Rosenström U, Axelsson H, ..., Lundbäck T, Larhed M

Assay Drug Dev Technol 14 (3) 180-193 [2016-04-00; online 2016-04-15]

Affiliated researcher

PubMed DOI Crossref

Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research.

Spjuth O, Krestyaninova M, Hastings J, ..., Prokopenko I, Harris JR

Eur. J. Hum. Genet. 24 (4) 521-528 [2016-04-00; online 2015-08-26]

Affiliated researcher

PubMed DOI Crossref

Global gray-level thresholding based on object size.

Ranefall P, Wählby C

Cytometry A 89 (4) 385-390 [2016-04-00; online 2016-01-22]

Affiliated researcher

PubMed DOI Crossref

Genomic legacies of the progenitors and the evolutionary consequences of allopolyploidy.

Steige KA, Slotte T

Current Opinion in Plant Biology 30 (-) 88-93 [2016-04-00; online 2016-03-01]

Affiliated researcher SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Evolutionary Origins of Rhizarian Parasites.

Sierra R, Cañas-Duarte SJ, Burki F, ..., Arzul I, Pawlowski J

Mol. Biol. Evol. 33 (4) 980-983 [2016-04-00; online 2015-12-16]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

DeMix-Q: Quantification-Centered Data Processing Workflow.

Zhang B, Käll L, Zubarev RA

Mol. Cell Proteomics 15 (4) 1467-1478 [2016-04-00; online 2016-01-04]

Affiliated researcher

PubMed DOI Crossref

Commercially Available Preparations of Recombinant Wnt3a Contain Non-Wnt Related Activities Which May Activate TGF-β Signaling.

Carthy JM, Engström U, Heldin CH, Moustakas A

J. Cell. Biochem. 117 (4) 938-945 [2016-04-00; online 2015-09-22]

Affiliated researcher

PubMed DOI Crossref

Binding to and Inhibition of Insulin-Regulated Aminopeptidase by Macrocyclic Disulfides Enhances Spine Density.

Diwakarla S, Nylander E, Grönbladh A, ..., Chai SY, Hallberg M

Molecular Pharmacology 89 (4) 413-424 [2016-04-00; online 2016-01-14]

Affiliated researcher

PubMed DOI Crossref

Acute neuroinflammation in a clinically relevant focal cortical ischemic stroke model in rat: longitudinal positron emission tomography and immunofluorescent tracking.

Tóth M, Little P, Arnberg F, ..., Gulyás B, Holmin S

Brain Struct Funct 221 (3) 1279-1290 [2016-04-00; online 2015-01-20]

Affiliated researcher

PubMed DOI Crossref

A multiple-phenotype imputation method for genetic studies.

Dahl A, Iotchkova V, Baud A, ..., Kranis A, Marchini J

Nat. Genet. 48 (4) 466-472 [2016-04-00; online 2016-02-22]

Affiliated researcher

PubMed DOI Crossref

Shotgun proteomics to unravel marine mussel (Mytilus edulis) response to long-term exposure to low salinity and propranolol in a Baltic Sea microcosm.

Campos A, Danielsson G, Farinha AP, ..., Warholm P, Cristobal S

J Proteomics 137 (-) 97-106 [2016-03-30; online 2016-01-26]

Affiliated researcher

DOI Crossref

A Facile Synthesis of NODASA-Functionalized Peptide

Naicker T, Albericio F, Dutta J, ..., Kruger H, Govender T

Synlett 27 (11) 1685-1688 [2016-03-30; online 2016-03-30]

Affiliated researcher

PubMed

Alterations in the membrane-associated proteome fraction of alveolar macrophages in sarcoidosis.

Kjellin H, Silva E, Branca RM, ..., Lehtiö J, Wheelock ÅM

Sarcoidosis Vasc Diffuse Lung Dis 33 (1) 17-28 [2016-03-29; online 2016-03-29]

Affiliated researcher

PubMed DOI Crossref

Trigger Factor Reduces the Force Exerted on the Nascent Chain by a Cotranslationally Folding Protein.

Nilsson OB, Müller-Lucks A, Kramer G, Bukau B, von Heijne G

J. Mol. Biol. 428 (6) 1356-1364 [2016-03-27; online 2016-02-18]

Affiliated researcher

PubMed DOI Crossref

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil.

Almqvist H, Axelsson H, Jafari R, ..., Lundbäck T, Nordlund P

Nat Commun 7 (-) 11040 [2016-03-24; online 2016-03-24]

Affiliated researcher

PubMed DOI Crossref

VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread.

Li X, Padhan N, Sjöström EO, ..., Jansson L, Claesson-Welsh L

Nat Commun 7 (-) 11017 [2016-03-23; online 2016-03-23]

Affiliated researcher

PubMed DOI Crossref

System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis.

Pozniak Y, Balint-Lahat N, Rudolph JD, ..., Barshack I, Geiger T

Cell Systems 2 (3) 172-184 [2016-03-23; online 2016-03-03]

Affiliated researcher

PubMed DOI Crossref

Metagenomic analysis of bloodstream infections in patients with acute leukemia and therapy-induced neutropenia.

Gyarmati P, Kjellander C, Aust C, ..., Öhrmalm L, Giske CG

Sci Rep 6 (-) 23532 [2016-03-21; online 2016-03-21]

Affiliated researcher

PubMed DOI Crossref

PON-mt-tRNA: a multifactorial probability-based method for classification of mitochondrial tRNA variations.

Niroula A, Vihinen M

Nucleic Acids Res. 44 (5) 2020-2027 [2016-03-18; online 2016-02-03]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

On-Water Synthesis of Biaryl Sulfonyl Fluorides.

Chinthakindi PK, Kruger HG, Govender T, Naicker T, Arvidsson PI

J. Org. Chem. 81 (6) 2618-2623 [2016-03-18; online 2016-02-29]

Affiliated researcher

PubMed DOI Crossref

Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes.

Geny S, Moreno PM, Krzywkowski T, ..., Wengel J, Smith CI

Nucleic Acids Res. 44 (5) 2007-2019 [2016-03-18; online 2016-02-08]

Affiliated researcher

PubMed DOI Crossref

Multiple Gene Repression in Cyanobacteria Using CRISPRi.

Yao L, Cengic I, Anfelt J, Hudson EP

ACS Synth. Biol. 5 (3) 207-212 [2016-03-18; online 2015-12-28]

Affiliated researcher Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

Biological insertion of computationally designed short transmembrane segments.

Baeza-Delgado C, von Heijne G, Marti-Renom MA, Mingarro I

Sci Rep 6 (-) 23397 [2016-03-18; online 2016-03-18]

Affiliated researcher

PubMed DOI Crossref

PopulationProfiler: A Tool for Population Analysis and Visualization of Image-Based Cell Screening Data.

Matuszewski DJ, Wählby C, Puigvert JC, Sintorn IM

PLoS ONE 11 (3) e0151554 [2016-03-17; online 2016-03-17]

Affiliated researcher

PubMed DOI Crossref

In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes.

Wiśniewski JR, Vildhede A, Norén A, Artursson P

J Proteomics 136 (-) 234-247 [2016-03-16; online 2016-01-26]

Affiliated researcher

PubMed DOI Crossref

Use of Time-Resolved Fluorescence To Improve Sensitivity and Dynamic Range of Gel-Based Proteomics.

Sandberg A, Buschmann V, Kapusta P, Erdmann R, Wheelock ÅM

Anal. Chem. 88 (6) 3067-3074 [2016-03-15; online 2016-02-22]

Affiliated researcher

PubMed DOI Crossref

NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis.

Tervaniemi MH, Katayama S, Skoog T, ..., Kere J, Elomaa O

Sci Rep 6 (-) 22745 [2016-03-15; online 2016-03-15]

Affiliated researcher

PubMed DOI Crossref

Landscape and Dynamics of Transcription Initiation in the Malaria Parasite Plasmodium falciparum.

Adjalley SH, Chabbert CD, Klaus B, Pelechano V, Steinmetz LM

Cell Reports 14 (10) 2463-2475 [2016-03-15; online 2016-03-03]

Affiliated researcher SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

FoCuS-point: software for STED fluorescence correlation and time-gated single photon counting.

Waithe D, Clausen MP, Sezgin E, Eggeling C

Bioinformatics 32 (6) 958-960 [2016-03-15; online 2015-11-20]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Luminescent Nanocellulose Platform: From Controlled Graft Block Copolymerization to Biomarker Sensing.

Navarro JR, Wennmalm S, Godfrey J, Breitholtz M, Edlund U

Biomacromolecules 17 (3) 1101-1109 [2016-03-14; online 2016-01-29]

Affiliated researcher

PubMed DOI Crossref

Glycation Reactivity of a Quorum-Sensing Signaling Molecule.

Tsuchikama K, Gooyit M, Harris TL, ..., Kaufmann GF, Janda KD

Angew. Chem. Int. Ed. Engl. 55 (12) 4002-4006 [2016-03-14; online 2016-02-17]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII.

Talibov VO, Linkuvienė V, Matulis D, Danielson UH

J. Med. Chem. 59 (5) 2083-2093 [2016-03-10; online 2016-02-08]

Affiliated researcher

PubMed DOI Crossref

Engineering Cellular Metabolism.

Nielsen J, Keasling JD

Cell 164 (6) 1185-1197 [2016-03-10; online 2016-03-12]

Affiliated researcher

PubMed DOI Crossref

Evolutionary history of host use, rather than plant phylogeny, determines gene expression in a generalist butterfly.

Celorio-Mancera Mde L, Wheat CW, Huss M, ..., Nylin S, Janz N

BMC Evol Biol BMC Evolutionary Biology 16 (-) 59 [2016-03-08; online 2016-03-08]

Affiliated researcher

PubMed DOI Crossref

Whole genome sequencing identifies a novel species of the genus Capnocytophaga isolated from dog and cat bite wounds in humans.

Zangenah S, Abbasi N, Andersson AF, Bergman P

Sci Rep 6 (-) 22919 [2016-03-07; online 2016-03-07]

Affiliated researcher

PubMed DOI Crossref

Mechanistic investigation of the on-surface enzymatic digestion (oSED) protein adsorption detection method using targeted mass spectrometry.

Undin T, Dahlin A, Hörnaeus K, Bergquist J, Lind SB

Analyst 141 (5) 1714-1720 [2016-03-07; online 2016-02-13]

Affiliated researcher

PubMed DOI Crossref

Lesion Size Is Exacerbated in Hypoxic Rats Whereas Hypoxia-Inducible Factor-1 Alpha and Vascular Endothelial Growth Factor Increase in Injured Normoxic Rats: A Prospective Cohort Study of Secondary Hypoxia in Focal Traumatic Brain Injury.

Thelin EP, Frostell A, Mulder J, ..., Morganti-Kossmann MC, Bellander BM

Front Neurol 7 (-) 23 [2016-03-07; online 2016-03-07]

Affiliated researcher

PubMed DOI Crossref

Influence of mutations at the proximal histidine position on the Fe-O2 bond in hemoglobin from density functional theory.

Todde G, Hovmöller S, Laaksonen A

J Chem Phys 144 (9) 095101 [2016-03-07; online 2016-03-10]

Affiliated researcher

PubMed DOI Crossref

Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease.

Khoonsari PE, Häggmark A, Lönnberg M, ..., Kultima K, Shevchenko G

PLoS ONE 11 (3) e0150672 [2016-03-07; online 2016-03-07]

Affiliated researcher

PubMed DOI Crossref

MaRaCluster: A Fragment Rarity Metric for Clustering Fragment Spectra in Shotgun Proteomics.

The M, Käll L

J. Proteome Res. 15 (3) 713-720 [2016-03-04; online 2016-01-12]

Affiliated researcher

PubMed DOI Crossref

AP-1 Is a Key Regulator of Proinflammatory Cytokine TNFα-mediated Triple-negative Breast Cancer Progression.

Qiao Y, He H, Jonsson P, ..., Zhao C, Dahlman-Wright K

J. Biol. Chem. 291 (10) 5068-5079 [2016-03-04; online 2016-01-20]

Affiliated researcher

PubMed DOI Crossref

Fast, accurate, and lightweight analysis of BS-treated reads with ERNE 2.

Prezza N, Vezzi F, Käller M, Policriti A

BMC Bioinformatics 17 Suppl 4 (-) 69 [2016-03-02; online 2016-03-02]

Affiliated researcher

PubMed DOI Crossref

Cells release subpopulations of exosomes with distinct molecular and biological properties.

Willms E, Johansson HJ, Mäger I, ..., Wood MJ, Vader P

Sci Rep 6 (-) 22519 [2016-03-02; online 2016-03-02]

Affiliated researcher

PubMed DOI Crossref

The MHC Class I Cancer-Associated Neoepitope Trh4 Linked with Impaired Peptide Processing Induces a Unique Noncanonical TCR Conformer.

Hafstrand I, Doorduijn EM, Duru AD, ..., van Hall T, Achour A

J. Immunol. 196 (5) 2327-2334 [2016-03-01; online 2016-01-22]

Affiliated researcher

PubMed DOI Crossref

Specific small-RNA signatures in the amygdala at premotor and motor stages of Parkinson's disease revealed by deep sequencing analysis.

Pantano L, Friedländer MR, Escaramís G, ..., Estivill X, Martí E

Bioinformatics 32 (5) 673-681 [2016-03-01; online 2015-11-02]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Polymorphisms in genes in the androgen pathway and risk of Barrett's esophagus and esophageal adenocarcinoma.

Ek WE, Lagergren K, Cook M, ..., Westberg L, Lagergren J

Int. J. Cancer 138 (5) 1146-1152 [2016-03-01; online 2015-10-05]

Affiliated researcher

PubMed DOI Crossref

Metabolic Trade-offs in Yeast are Caused by F1F0-ATP synthase.

Nilsson A, Nielsen J

Sci Rep 6 (-) 22264 [2016-03-01; online 2016-03-01]

Avlant Nilsson DDLS Fellow

PubMed DOI Crossref

Estrogen receptor beta as target for colorectal cancer prevention.

Williams C, DiLeo A, Niv Y, Gustafsson JÅ

Cancer Lett. 372 (1) 48-56 [2016-03-01; online 2015-12-18]

Affiliated researcher

PubMed DOI Crossref

DNA-PKcs and PARP1 Bind to Unresected Stalled DNA Replication Forks Where They Recruit XRCC1 to Mediate Repair.

Ying S, Chen Z, Medhurst AL, ..., Meek K, Helleday T

Cancer Res. 76 (5) 1078-1088 [2016-03-01; online 2015-11-24]

Affiliated researcher

PubMed DOI Crossref

The metabolic fingerprint of p,p'-DDE and HCB exposure in humans.

Salihovic S, Ganna A, Fall T, ..., Ingelsson E, Lind L

Environ Int 88 (-) 60-66 [2016-03-00; online 2015-12-22]

Affiliated researcher

PubMed DOI Crossref

The influence of population structure on gene expression and flowering time variation in the ubiquitous weed Capsella bursa-pastoris (Brassicaceae).

Kryvokhyzha D, Holm K, Chen J, ..., Lagercrantz U, Lascoux M

Mol. Ecol. 25 (5) 1106-1121 [2016-03-00; online 2016-02-16]

Affiliated researcher

PubMed DOI Crossref

T-cell receptor-HLA-DRB1 associations suggest specific antigens in pulmonary sarcoidosis.

Grunewald J, Kaiser Y, Ostadkarampour M, ..., Ronninger M, Eklund A

Eur. Respir. J. 47 (3) 898-909 [2016-03-00; online 2015-11-19]

Affiliated researcher

PubMed DOI Crossref

Small protein domains fold inside the ribosome exit tunnel.

Marino J, von Heijne G, Beckmann R

FEBS Lett. 590 (5) 655-660 [2016-03-00; online 2016-02-25]

Affiliated researcher

DOI Crossref

Shape optimization of a cyclone separator using multi-objective surrogate-based optimization

Singh P, Couckuyt I, Elsayed K, Deschrijver D, Dhaene T

Applied Mathematical Modelling 40 (5-6) 4248-4259 [2016-03-00; online 2016-03-00]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

Second generation sequencing of microRNA in Human Bone Cells treated with Parathyroid Hormone or Dexamethasone.

Laxman N, Rubin CJ, Mallmin H, ..., Tellgren-Roth C, Kindmark A

Bone 84 (-) 181-188 [2016-03-00; online 2015-12-31]

Affiliated researcher

DOI Crossref

Rapid and straightforward transesterification of sulfonyl carbamates

Isaksson R, Kumpiņa I, Larhed M, Wannberg J

Tetrahedron Letters 57 (13) 1476-1478 [2016-03-00; online 2016-03-00]

Affiliated researcher

PubMed DOI Crossref

Oncogene-Induced Senescence in Pituitary Adenomas--an Immunohistochemical Study.

Manojlovic-Gacic E, Skender-Gazibara M, Popovic V, ..., Pontén F, Casar-Borota O

Endocr. Pathol. 27 (1) 1-11 [2016-03-00; online 2015-11-18]

Affiliated researcher

PubMed DOI Crossref

Normalization of circulating microRNA expression data obtained by quantitative real-time RT-PCR.

Marabita F, de Candia P, Torri A, ..., Abrignani S, Rossi RL

Brief. Bioinformatics 17 (2) 204-212 [2016-03-00; online 2015-08-03]

Affiliated researcher

PubMed DOI Crossref

Immune Adaptation to Environmental Influence: The Case of NK Cells and HCMV.

Rölle A, Brodin P

Trends Immunol. 37 (3) 233-243 [2016-03-00; online 2016-02-09]

Affiliated researcher

PubMed DOI Crossref

Identification of novel genetic causes of Rett syndrome-like phenotypes.

Lopes F, Barbosa M, Ameur A, ..., Pinto D, Maciel P

J. Med. Genet. 53 (3) 190-199 [2016-03-00; online 2016-01-06]

Affiliated researcher

DOI Crossref

Geographical range in liverworts: does sex really matter?

Laenen B, Machac A, Gradstein SR, ..., Shaw J, Vanderpoorten A

J. Biogeogr. 43 (3) 627-635 [2016-03-00; online 2015-11-04]

Affiliated researcher

PubMed DOI Crossref

Gene expression signatures, pathways and networks in carotid atherosclerosis.

Perisic L, Aldi S, Sun Y, ..., Paulsson-Berne G, Hedin U

J. Intern. Med. 279 (3) 293-308 [2016-03-00; online 2015-11-30]

Affiliated researcher

PubMed DOI Crossref

Experimental insights into the importance of aquatic bacterial community composition to the degradation of dissolved organic matter.

Logue JB, Stedmon CA, Kellerman AM, ..., Lindström ES, Kritzberg ES

ISME J 10 (3) 533-545 [2016-03-00; online 2015-08-21]

Affiliated researcher

PubMed DOI Crossref

Evaluating network inference methods in terms of their ability to preserve the topology and complexity of genetic networks.

Kiani NA, Zenil H, Olczak J, Tegnér J

Semin. Cell Dev. Biol. 51 (-) 44-52 [2016-03-00; online 2016-02-03]

Affiliated researcher

PubMed DOI Crossref

Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma.

Ambrogio C, Gómez-López G, Falcone M, ..., Santamaría D, Barbacid M

Nat. Med. 22 (3) 270-277 [2016-03-00; online 2016-02-08]

Affiliated researcher

PubMed DOI Crossref

Arabidopsis acyl-acyl carrier protein synthetase AAE15 with medium chain fatty acid specificity is functional in cyanobacteria.

Kaczmarzyk D, Hudson EP, Fulda M

AMB Expr 6 (1) 7 [2016-03-00; online 2016-01-21]

Affiliated researcher Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients.

Kirchner H, Sinha I, Gao H, ..., Dahlman-Wright K, Zierath JR

Mol Metab 5 (3) 171-183 [2016-03-00; online 2016-01-02]

Affiliated researcher

PubMed DOI Crossref

A comparative study of phosphopeptide-selective techniques for a sub-proteome of a complex biological sample.

Källsten M, Bergquist J, Zhao H, Konzer A, Lind SB

Anal Bioanal Chem 408 (9) 2347-2356 [2016-03-00; online 2016-02-17]

Affiliated researcher

PubMed DOI Crossref

Molecularly designed lipid microdomains for solid dispersions using a polymer/inorganic carrier matrix produced by hot-melt extrusion.

Adler C, Schönenberger M, Teleki A, Kuentz M

Int J Pharm 499 (1-2) 90-100 [2016-02-29; online 2015-12-22]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients.

Schwieler L, Samuelsson M, Frye MA, ..., Sellgren CM, Erhardt S

J Neuroinflammation 13 (1) 51 [2016-02-29; online 2016-02-29]

Affiliated researcher

PubMed DOI Crossref

Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations.

Ljungström V, Cortese D, Young E, ..., Sjöblom T, Rosenquist R

Blood 127 (8) 1007-1016 [2016-02-25; online 2015-12-16]

Affiliated researcher

PubMed DOI Crossref

Bioelectric and Morphological Response of Liquid-Covered Human Airway Epithelial Calu-3 Cell Monolayer to Periodic Deposition of Colloidal 3-Mercaptopropionic-Acid Coated CdSe-CdS/ZnS Core-Multishell Quantum Dots.

Turdalieva A, Solandt J, Shambetova N, ..., Zelenina M, Fu Y

PLoS ONE 11 (2) e0149915 [2016-02-25; online 2016-02-25]

Affiliated researcher

PubMed DOI Crossref

A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients.

Lind AL, Wu D, Freyhult E, ..., Landegren U, Kamali-Moghaddam M

PLoS ONE 11 (2) e0149821 [2016-02-25; online 2016-02-25]

Affiliated researcher

PubMed DOI Crossref

Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.

Newman JA, Cooper CD, Roos AK, ..., Osman R, Gileadi O

PLoS ONE 11 (2) e0148762 [2016-02-24; online 2016-02-24]

Affiliated researcher

DOI Crossref

An Efficient Protecting-Group-Free Synthesis of Vinylic Sulfoximines via Horner–Wadsworth–Emmons Reaction

Naicker T, Arvidsson P, Chinthakindi P, ..., Govender T, Kruger H

Synlett 27 (09) 1423-1427 [2016-02-24; online 2016-02-24]

Affiliated researcher

PubMed DOI Crossref

Anoctamin 2 identified as an autoimmune target in multiple sclerosis.

Ayoglu B, Mitsios N, Kockum I, ..., Olsson T, Nilsson P

Proc. Natl. Acad. Sci. U.S.A. 113 (8) 2188-2193 [2016-02-23; online 2016-02-09]

Affiliated researcher

PubMed DOI Crossref

Stepwise nucleosome translocation by RSC remodeling complexes.

Harada BT, Hwang WL, Deindl S, ..., Bartholomew B, Zhuang X

Elife 5 (-) - [2016-02-19; online 2016-02-19]

SciLifeLab Fellow Sebastian Deindl

DOI Crossref

Microwave Promoted Transcarbamylation Reaction of Sulfonylcarbamates under Continuous-Flow Conditions

Kumpiņa I, Isaksson R, Sävmarker J, Wannberg J, Larhed M

Org. Process Res. Dev. 20 (2) 440-445 [2016-02-19; online 2016-01-05]

Affiliated researcher

PubMed DOI Crossref

AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics.

Eketjäll S, Janson J, Kaspersson K, ..., Alexander RC, Cebers G

J. Alzheimers Dis. 50 (4) 1109-1123 [2016-02-19; online 2016-02-19]

Affiliated researcher

PubMed DOI Crossref

GeneiASE: Detection of condition-dependent and static allele-specific expression from RNA-seq data without haplotype information.

Edsgärd D, Iglesias MJ, Reilly SJ, ..., Odeberg J, Emanuelsson O

Sci Rep 6 (-) 21134 [2016-02-18; online 2016-02-18]

Affiliated researcher

DOI Crossref

Acid Dissociation of 3-Mercaptopropionic Acid Coated CdSe–CdS/Cd0.5Zn0.5S/ZnS Core–Multishell Quantum Dot and Strong Ionic Interaction with Ca2+ Ion

Shambetova N, Chen Y, Xu H, ..., Brismar H, Fu Y

J. Phys. Chem. C 120 (6) 3519-3529 [2016-02-18; online 2016-02-09]

Affiliated researcher

PubMed DOI Crossref

Genomic inference of the metabolism of cosmopolitan subsurface Archaea, Hadesarchaea.

Baker BJ, Saw JH, Lind AE, ..., Teske AP, Ettema TJ

Nat. Microbiol 1 (-) 16002 [2016-02-15; online 2016-02-15]

Affiliated researcher

PubMed DOI Crossref

Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15.

Ek WE, Hedman ÅK, Enroth S, ..., Lind L, Johansson Å

Hum. Mol. Genet. 25 (4) 817-827 [2016-02-15; online 2015-12-17]

Affiliated researcher

PubMed DOI Crossref

Exome sequencing in one family with gastric- and rectal cancer.

Thutkawkorapin J, Picelli S, Kontham V, ..., Nilsson D, Lindblom A

BMC Genet. 17 (-) 41 [2016-02-13; online 2016-02-13]

Affiliated researcher

PubMed DOI Crossref

PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites.

Mortusewicz O, Evers B, Helleday T

Oncogene 35 (6) 761-770 [2016-02-11; online 2015-05-11]

Affiliated researcher

PubMed DOI Crossref

Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1.

Llona-Minguez S, Höglund A, Jacques SA, ..., Scobie M, Helleday T

J. Med. Chem. 59 (3) 1140-1148 [2016-02-11; online 2016-01-27]

Affiliated researcher

PubMed DOI Crossref

A Flexible Computational Framework Using R and Map-Reduce for Permutation Tests of Massive Genetic Analysis of Complex Traits.

Mahjani B, Toor S, Nettelblad C, Holmgren S

IEEE/ACM Trans Comput Biol Bioinform 14 (2) 381-392 [2016-02-11; online 2016-02-11]

Affiliated researcher

PubMed DOI Crossref

Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target.

Agarwal P, Alzrigat M, Párraga AA, ..., Kalushkova A, Jernberg-Wiklund H

Oncotarget 7 (6) 6809-6823 [2016-02-09; online 2016-01-13]

Affiliated researcher

DOI Crossref

Fast Zeta Transforms for Lattices with Few Irreducibles

Björklund A, Husfeldt T, Kaski P, ..., Nederlof J, Parviainen P

TALG ACM Trans. Algorithms 12 (1) 1-19 [2016-02-08; online 2015-12-31]

Affiliated researcher

DOI Crossref

Stereoselective synthesis towards unnatural proline based amino acids

- 2016 (3) 134 [2016-02-07; online 2016-02-07]

Affiliated researcher

PubMed DOI Crossref

Systems Proteomics View of the Endogenous Human Claudin Protein Family.

Liu F, Koval M, Ranganathan S, ..., Kelleher NL, Baker MS

J. Proteome Res. 15 (2) 339-359 [2016-02-05; online 2016-01-12]

Affiliated researcher

PubMed DOI Crossref

The metabolic background is a global player in Saccharomyces gene expression epistasis

Alam MT, Zelezniak A, Mülleder M, ..., Lilley KS, Ralser M

Nat. Microbiol 1 (3) 15030 [2016-02-01; online 2016-02-01]

Aleksej Zelezniak SciLifeLab Fellow

PubMed DOI Crossref

TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity.

Moudry P, Watanabe K, Wolanin KM, ..., Lukas J, Bartek J

J. Cell Biol. 212 (3) 281-288 [2016-02-01; online 2016-01-25]

Affiliated researcher

PubMed DOI Crossref

Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1.

Landegren N, Sharon D, Freyhult E, ..., Snyder M, Kämpe O

Sci Rep 6 (-) 20104 [2016-02-01; online 2016-02-01]

Affiliated researcher

PubMed DOI Crossref

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.

Lu Y, Day FR, Gustafsson S, ..., Kilpeläinen TO, Loos RJ

Nat Commun 7 (-) 10495 [2016-02-01; online 2016-02-01]

Affiliated researcher

PubMed DOI Crossref

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.

Kilpeläinen TO, Carli JF, Skowronski AA, ..., Leibel RL, Loos RJ

Nat Commun 7 (-) 10494 [2016-02-01; online 2016-02-01]

Affiliated researcher

PubMed DOI Crossref

Xeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulation.

Puumalainen MR, Rüthemann P, Min JH, Naegeli H

Cell. Mol. Life Sci. 73 (3) 547-566 [2016-02-00; online 2015-10-31]

Affiliated researcher

PubMed DOI Crossref

The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition.

Ölander M, Wiśniewski JR, Matsson P, Lundquist P, Artursson P

J Pharm Sci 105 (2) 817-827 [2016-02-00; online 2016-01-09]

Affiliated researcher

PubMed DOI Crossref

TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors.

Doorduijn EM, Sluijter M, Querido BJ, ..., van der Burg SH, van Hall T

J. Clin. Invest. 126 (2) 784-794 [2016-02-00; online 2016-01-19]

Affiliated researcher

PubMed DOI Crossref

Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.

Choi SH, Ruggiero D, Sorice R, ..., Seshadri S, Ciullo M

PLoS Genet 12 (2) e1005874 [2016-02-00; online 2016-02-24]

Affiliated researcher

PubMed DOI Crossref

Simvastatin and zinc synergistically enhance osteoblasts activity and decrease the acute response of inflammatory cells.

Montazerolghaem M, Ning Y, Engqvist H, ..., Tenje M, Mestres G

J Mater Sci Mater Med 27 (2) 23 [2016-02-00; online 2015-12-24]

Affiliated researcher

DOI Crossref

Segmentation and Track-Analysis in Time-Lapse Imaging of Bacteria

Sadanandan SK, Baltekin O, Magnusson KEG, ..., Elf J, Wahlby C

IEEE J. Sel. Top. Signal Process. 10 (1) 174-184 [2016-02-00; online 2016-02-00]

Affiliated researcher

PubMed DOI Crossref

Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses.

Imsland F, McGowan K, Rubin CJ, ..., Barsh GS, Andersson L

Nat. Genet. 48 (2) 152-158 [2016-02-00; online 2015-12-21]

Affiliated researcher

PubMed DOI Crossref

RAD-seq data point to a northern origin of the arctic-alpine genus Cassiope (Ericaceae).

Hou Y, Nowak MD, Mirré V, ..., Brochmann C, Popp M

Mol. Phylogenet. Evol. 95 (-) 152-160 [2016-02-00; online 2015-12-09]

Affiliated researcher

PubMed DOI Crossref

Oufti: an integrated software package for high-accuracy, high-throughput quantitative microscopy analysis.

Paintdakhi A, Parry B, Campos M, ..., Surovtsev I, Jacobs-Wagner C

Mol. Microbiol. 99 (4) 767-777 [2016-02-00; online 2015-12-18]

Affiliated researcher

PubMed DOI Crossref

Next-generation sequencing of the basal cell carcinoma miRNome and a description of novel microRNA candidates under neoadjuvant vismodegib therapy: an integrative molecular and surgical case study.

Sand M, Bechara FG, Gambichler T, ..., Schnabel R, Hessam S

Ann. Oncol. 27 (2) 332-338 [2016-02-00; online 2015-11-16]

Affiliated researcher Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Mechanisms of action of bone morphogenetic proteins in cancer.

Davis H, Raja E, Miyazono K, Tsubakihara Y, Moustakas A

Cytokine Growth Factor Rev. 27 (-) 81-92 [2016-02-00; online 2015-11-24]

Affiliated researcher

PubMed DOI Crossref

Genome-wide quantification of 5'-phosphorylated mRNA degradation intermediates for analysis of ribosome dynamics.

Pelechano V, Wei W, Steinmetz LM

Nat Protoc 11 (2) 359-376 [2016-02-00; online 2016-01-28]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Genetic code expansion in stable cell lines enables encoded chromatin modification.

Elsässer SJ, Ernst RJ, Walker OS, Chin JW

Nat. Methods 13 (2) 158-164 [2016-02-00; online 2016-01-04]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12.

Mäkinen N, Aavikko M, Heikkinen T, ..., Bützow R, Vahteristo P

PLoS Genet 12 (2) e1005850 [2016-02-00; online 2016-02-18]

Affiliated researcher

PubMed DOI Crossref

Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma.

Haylock AK, Spiegelberg D, Mortensen AC, ..., Tolmachev V, Nestor MV

Int. J. Oncol. 48 (2) 461-470 [2016-02-00; online 2015-12-14]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Epigenetic profiling in CD4+ and CD8+ T cells from Graves' disease patients reveals changes in genes associated with T cell receptor signaling.

Limbach M, Saare M, Tserel L, ..., Milani L, Peterson P

J. Autoimmun. 67 (-) 46-56 [2016-02-00; online 2015-10-12]

Affiliated researcher

PubMed DOI Crossref

Decreased levels of stem cell factor in subjects with incident coronary events.

Wigren M, Rattik S, Hultman K, ..., Gonçalves I, Nilsson J

J. Intern. Med. 279 (2) 180-191 [2016-02-00; online 2015-10-14]

Affiliated researcher

PubMed DOI Crossref

Correlating chemical sensitivity and basal gene expression reveals mechanism of action.

Rees MG, Seashore-Ludlow B, Cheah JH, ..., Shamji AF, Schreiber SL

Nat. Chem. Biol. 12 (2) 109-116 [2016-02-00; online 2015-12-14]

Affiliated researcher

PubMed DOI Crossref

Control of growth factor binding and release in bisphosphonate functionalized hydrogels guides rapid differentiation of precursor cells in vitro.

Kootala S, Zhang Y, Ghalib S, ..., Hilborn J, Ossipov DA

Biomater Sci 4 (2) 250-254 [2016-02-00; online 2015-11-28]

Affiliated researcher

PubMed DOI Crossref

Computational Cancer Biology: An Evolutionary Perspective.

Beerenwinkel N, Greenman CD, Lagergren J

PLoS Comput Biol 12 (2) e1004717 [2016-02-00; online 2016-02-04]

Affiliated researcher

PubMed DOI Crossref

Complete Knockout of Endogenous Mdr1 ( Abcb1 ) in MDCK Cells by CRISPR-Cas9

Simoff I, Karlgren M, Backlund M, ..., Matsson P, Artursson P

Journal of Pharmaceutical Sciences 105 (2) 1017-1021 [2016-02-00; online 2016-02-00]

Affiliated researcher

PubMed DOI Crossref

Cardiovascular disease and mortality after a first episode of venous thromboembolism in young and middle-aged women.

Ljungqvist M, Holmström M, Kieler H, Odeberg J, Lärfars G

Thromb. Res. 138 (-) 80-85 [2016-02-00; online 2015-12-02]

Affiliated researcher

PubMed DOI Crossref

Association between levels of pentraxin 3 and incidence of chronic kidney disease in the elderly.

Sjöberg B, Qureshi AR, Heimbürger O, ..., Bárány P, Ärnlöv J

J. Intern. Med. 279 (2) 173-179 [2016-02-00; online 2015-09-09]

Affiliated researcher

PubMed DOI Crossref

Are freshwater bacterioplankton indifferent to variable types of amino acid substrates?

Ricão Canelhas M, Eiler A, Bertilsson S

FEMS Microbiol. Ecol. 92 (2) - [2016-02-00; online 2016-01-05]

Affiliated researcher

PubMed DOI Crossref

Analysis of hepatitis C NS5A resistance associated polymorphisms using ultra deep single molecule real time (SMRT) sequencing.

Bergfors A, Leenheer D, Bergqvist A, Ameur A, Lennerstrand J

Antiviral Res. 126 (-) 81-89 [2016-02-00; online 2015-12-19]

Affiliated researcher

PubMed DOI Crossref

Active transposable elements recover species boundaries and geographic structure in Madagascan coffee species.

Roncal J, Guyot R, Hamon P, ..., Davis AP, de Kochko A

Mol. Genet. Genomics 291 (1) 155-168 [2016-02-00; online 2015-08-01]

Affiliated researcher

PubMed DOI Crossref

A comparative study on fluorescent cholesterol analogs as versatile cellular reporters.

Sezgin E, Can FB, Schneider F, ..., Platt F, Eggeling C

J. Lipid Res. 57 (2) 299-309 [2016-02-00; online 2015-12-23]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Cellular microenvironment controls the nuclear architecture of breast epithelia through β1-integrin.

Maya-Mendoza A, Bartek J, Jackson DA, Streuli CH

Cell Cycle 15 (3) 345-356 [2016-01-29; online 2016-01-29]

Affiliated researcher

PubMed DOI Crossref

Atomistic Simulation of Protein Encapsulation in Metal-Organic Frameworks.

Zhang H, Lv Y, Tan T, van der Spoel D

J Phys Chem B 120 (3) 477-484 [2016-01-28; online 2016-01-15]

Affiliated researcher

PubMed DOI Crossref

Untangling the early diversification of eukaryotes: a phylogenomic study of the evolutionary origins of Centrohelida, Haptophyta and Cryptista.

Burki F, Kaplan M, Tikhonenkov DV, ..., Mylnikov AP, Keeling PJ

Proc. Biol. Sci. 283 (1823) 20152802 [2016-01-27; online 2016-01-27]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Recent advances in understanding Type 1 Diabetes.

Christoffersson G, Rodriguez-Calvo T, von Herrath M

F1000Res 5 (-) - [2016-01-27; online 2016-01-27]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes.

Walker OS, Elsässer SJ, Mahesh M, ..., Balasubramanian S, Chin JW

Journal of the American Chemical Society 138 (3) 718-721 [2016-01-27; online 2016-01-12]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels.

Cavalli M, Pan G, Nord H, Wadelius C

Lipids Health Dis 15 (-) 18 [2016-01-27; online 2016-01-27]

Affiliated researcher

PubMed DOI Crossref

Genomic sequencing of a dyslexia susceptibility haplotype encompassing ROBO1.

Massinen S, Wang J, Laivuori K, ..., Jiao H, Kere J

J Neurodev Disord 8 (-) 4 [2016-01-27; online 2016-01-27]

Affiliated researcher

PubMed DOI Crossref

Personalized Cardiovascular Disease Prediction and Treatment-A Review of Existing Strategies and Novel Systems Medicine Tools.

Björnson E, Borén J, Mardinoglu A

Front. Physiol. 7 (-) 2 [2016-01-26; online 2016-01-26]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

HPA Axis Gene Expression and DNA Methylation Profiles in Rats Exposed to Early Life Stress, Adult Voluntary Ethanol Drinking and Single Housing.

Todkar A, Granholm L, Aljumah M, ..., Comasco E, Nylander I

Front Mol Neurosci 8 (-) 90 [2016-01-26; online 2016-01-26]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

A survey of best practices for RNA-seq data analysis.

Conesa A, Madrigal P, Tarazona S, ..., Zhang X, Mortazavi A

Genome Biol. 17 (-) 13 [2016-01-26; online 2016-01-26]

Affiliated researcher

PubMed DOI Crossref

Exploration of Interfacial Hydration Networks of Target-Ligand Complexes.

Jeszenői N, Bálint M, Horváth I, van der Spoel D, Hetényi C

J Chem Inf Model 56 (1) 148-158 [2016-01-25; online 2016-01-08]

Affiliated researcher

PubMed DOI Crossref

Proadifen sensitizes resistant ovarian adenocarcinoma cells to cisplatin.

Jendželovský R, Jendželovská Z, Hiľovská L, ..., Mikeš J, Fedoročko P

Toxicol. Lett. 243 (-) 56-66 [2016-01-22; online 2015-12-22]

Affiliated researcher

PubMed DOI Crossref

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.

Pattaro C, Teumer A, Gorski M, ..., Kao WH, Fox CS

Nat Commun 7 (-) 10023 [2016-01-21; online 2016-01-21]

Affiliated researcher

PubMed DOI Crossref

Reconstructing ecosystem functions of the active microbial community of the Baltic Sea oxygen depleted sediments.

Thureborn P, Franzetti A, Lundin D, Sjöling S

PeerJ 4 (-) e1593 [2016-01-19; online 2016-01-19]

Affiliated researcher

PubMed DOI Crossref

Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation.

Bahram F, Hydbring P, Tronnersjö S, ..., Castell A, Larsson LG

Oncotarget 7 (3) 2837-2854 [2016-01-19; online 2015-12-25]

Affiliated researcher

PubMed DOI Crossref

Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids.

Kloster-Jensen K, Sahraoui A, Vethe NT, ..., Foss A, Scholz H

J Diabetes Res 2016 (-) 4196460 [2016-01-18; online 2016-01-18]

Affiliated researcher

PubMed DOI Crossref

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes.

Kürten C, Syrén PO

J Vis Exp - (107) e53168 [2016-01-16; online 2016-01-16]

Affiliated researcher

PubMed DOI Crossref

Using Whole-Exome Sequencing to Identify Genetic Markers for Carboplatin and Gemcitabine-Induced Toxicities.

Gréen H, Hasmats J, Kupershmidt I, ..., Peterson C, Lundeberg J

Clin. Cancer Res. 22 (2) 366-373 [2016-01-15; online 2015-09-16]

Affiliated researcher

PubMed DOI Crossref

Predicting unintended effects of drugs based on off-target tissue effects.

Kim D, Lee J, Lee S, Park J, Lee D

Biochem. Biophys. Res. Commun. 469 (3) 399-404 [2016-01-15; online 2015-12-02]

Affiliated researcher

PubMed DOI Crossref

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.

de Vries PS, Chasman DI, Sabater-Lleal M, ..., Strachan DP, Dehghan A

Hum. Mol. Genet. 25 (2) 358-370 [2016-01-15; online 2015-11-10]

Affiliated researcher

PubMed DOI Crossref

Depression or anxiety and all-cause mortality in adults with atrial fibrillation--A cohort study in Swedish primary care.

Wändell P, Carlsson AC, Gasevic D, ..., Sundquist J, Sundquist K

Ann. Med. 48 (1-2) 59-66 [2016-01-13; online 2016-01-13]

Affiliated researcher

PubMed DOI Crossref

Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin.

Elokely K, Velisetty P, Delemotte L, ..., Rohacs T, Carnevale V

Proc. Natl. Acad. Sci. U.S.A. 113 (2) E137-E145 [2016-01-12; online 2015-12-30]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling.

Raja E, Tzavlaki K, Vuilleumier R, ..., Heldin CH, Moustakas A

Oncotarget 7 (2) 1120-1143 [2016-01-12; online 2015-12-25]

Affiliated researcher

PubMed DOI Crossref

Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development.

Johansson MM, Lundin E, Qian X, ..., Nilsson M, Jazin E

Biol Sex Differ 7 (-) 5 [2016-01-12; online 2016-01-12]

Affiliated researcher

PubMed DOI Crossref

Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells.

Darmanis S, Gallant CJ, Marinescu VD, ..., Westermark B, Landegren U

Cell Reports 14 (2) 380-389 [2016-01-12; online 2015-12-31]

Affiliated researcher

PubMed DOI Crossref

Influence of pre-existing inflammation on the outcome of acute coronary syndrome: a cross-sectional study.

Odeberg J, Freitag M, Forssell H, ..., Råstam L, Lindblad U

BMJ Open 6 (1) e009968 [2016-01-12; online 2016-01-12]

Affiliated researcher

PubMed DOI Crossref

Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis.

Bersani C, Huss M, Giacomello S, ..., Lui WO, Wiman KG

Oncotarget 7 (2) 1895-1911 [2016-01-12; online 2015-12-18]

Affiliated researcher

PubMed DOI Crossref

Confounding Effects of Metformin on the Human Gut Microbiome in Type 2 Diabetes.

Mardinoglu A, Boren J, Smith U

Cell Metab. 23 (1) 10-12 [2016-01-12; online 2016-01-16]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities.

Sanjiv K, Hagenkort A, Calderón-Montaño JM, ..., Altun M, Helleday T

Cell Reports 14 (2) 298-309 [2016-01-12; online 2015-12-31]

Affiliated researcher

PubMed DOI Crossref

BMP Sustains Embryonic Stem Cell Self-Renewal through Distinct Functions of Different Krüppel-like Factors.

Morikawa M, Koinuma D, Mizutani A, ..., Heldin CH, Miyazono K

Stem Cell Reports 6 (1) 64-73 [2016-01-12; online 2016-01-16]

Affiliated researcher

PubMed DOI Crossref

Knock-down of ZBED6 in insulin-producing cells promotes N-cadherin junctions between beta-cells and neural crest stem cells in vitro.

Wang X, Xie B, Qi Y, ..., Kozlova EN, Welsh N

Sci Rep 6 (-) 19006 [2016-01-11; online 2016-01-11]

Affiliated researcher

PubMed DOI Crossref

APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain.

Song J, Mu Y, Li C, ..., Heldin CH, Landström M

Oncotarget 7 (1) 279-292 [2016-01-05; online 2015-11-20]

Affiliated researcher

PubMed DOI Crossref

Computer vision profiling of neurite outgrowth dynamics reveals spatiotemporal modularity of Rho GTPase signaling.

Fusco L, Lefort R, Smith K, ..., Fua P, Pertz O

J. Cell Biol. 212 (1) 91-111 [2016-01-04; online 2016-01-06]

Affiliated researcher

PubMed DOI Crossref

Case definitions in Swedish register data to identify systemic lupus erythematosus.

Arkema EV, Jönsen A, Rönnblom L, ..., Sjöwall C, Simard JF

BMJ Open 6 (1) e007769 [2016-01-04; online 2016-01-04]

Affiliated researcher

PubMed DOI Crossref

CRISPRz: a database of zebrafish validated sgRNAs.

Varshney GK, Zhang S, Pei W, ..., Sood R, Burgess SM

Nucleic Acids Res. 44 (D1) D822-D826 [2016-01-04; online 2015-10-04]

Affiliated researcher

PubMed DOI Crossref

Pivotal role of glycogen synthase kinase-3: A therapeutic target for Alzheimer's disease.

Maqbool M, Mobashir M, Hoda N

Eur J Med Chem 107 (-) 63-81 [2016-01-01; online 2015-10-21]

Affiliated researcher

PubMed DOI Crossref

Antigen Selection Shapes the T-cell Repertoire in Chronic Lymphocytic Leukemia.

Vardi A, Agathangelidis A, Stalika E, ..., Sutton LA, Stamatopoulos K

Clin. Cancer Res. 22 (1) 167-174 [2016-01-01; online 2015-09-02]

Affiliated researcher

PubMed DOI Crossref

hTERT promoter methylation in pituitary adenomas.

Köchling M, Ewelt C, Fürtjes G, ..., Stummer W, Brokinkel B

Brain Tumor Pathol 33 (1) 27-34 [2016-01-00; online 2015-09-21]

Affiliated researcher

PubMed DOI Crossref

The regulation of function, growth and survival of GLP-1-producing L-cells.

Kuhre RE, Holst JJ, Kappe C

Clin. Sci. 130 (2) 79-91 [2016-01-00; online 2015-12-08]

Affiliated researcher

PubMed DOI Crossref

The rate of adaptive evolution in animal mitochondria.

James JE, Piganeau G, Eyre-Walker A

Mol. Ecol. 25 (1) 67-78 [2016-01-00; online 2015-12-17]

DDLS Fellow Jennifer James

PubMed DOI Crossref

The WD40 Domain Protein MSI1 Functions in a Histone Deacetylase Complex to Fine-Tune Abscisic Acid Signaling.

Mehdi S, Derkacheva M, Ramström M, ..., Bergquist J, Hennig L

Plant Cell 28 (1) 42-54 [2016-01-00; online 2015-12-24]

Affiliated researcher

PubMed DOI Crossref

The Molecular Basis of Polyunsaturated Fatty Acid Interactions with the Shaker Voltage-Gated Potassium Channel.

Yazdi S, Stein M, Elinder F, Andersson M, Lindahl E

PLoS Comput Biol 12 (1) e1004704 [2016-01-00; online 2016-01-11]

Affiliated researcher

PubMed DOI Crossref

Targeting DNA repair, DNA metabolism and replication stress as anti-cancer strategies.

Puigvert JC, Sanjiv K, Helleday T

FEBS J. 283 (2) 232-245 [2016-01-00; online 2015-11-18]

Affiliated researcher

PubMed DOI Crossref

Super-resolution stimulated emission depletion imaging of slit diaphragm proteins in optically cleared kidney tissue.

Unnersjö-Jess D, Scott L, Blom H, Brismar H

Kidney Int. 89 (1) 243-247 [2016-01-00; online 2016-01-04]

Affiliated researcher

PubMed DOI Crossref

Structural genomic changes underlie alternative reproductive strategies in the ruff (Philomachus pugnax).

Lamichhaney S, Fan G, Widemo F, ..., Liu X, Andersson L

Nat. Genet. 48 (1) 84-88 [2016-01-00; online 2015-11-16]

Affiliated researcher

PubMed DOI Crossref

Protein Biomarkers for Insulin Resistance and Type 2 Diabetes Risk in Two Large Community Cohorts.

Nowak C, Sundström J, Gustafsson S, ..., Ingelsson E, Fall T

Diabetes 65 (1) 276-284 [2016-01-00; online 2015-09-29]

Affiliated researcher

PubMed DOI Crossref

Prediction impact curve is a new measure integrating intervention effects in the evaluation of risk models.

Campbell W, Ganna A, Ingelsson E, Janssens AC

J Clin Epidemiol 69 (-) 89-95 [2016-01-00; online 2015-06-25]

Affiliated researcher

PubMed DOI Crossref

Out of southern East Asia: the natural history of domestic dogs across the world.

Wang GD, Zhai W, Yang HC, ..., Savolainen P, Zhang YP

Cell Res. 26 (1) 21-33 [2016-01-00; online 2015-12-15]

Affiliated researcher

PubMed DOI Crossref

Non-invasive in vitro and in vivo monitoring of degradation of fluorescently labeled hyaluronan hydrogels for tissue engineering applications.

Zhang Y, Rossi F, Papa S, ..., Hilborn J, Ossipov DA

Acta Biomater 30 (-) 188-198 [2016-01-00; online 2015-11-24]

Affiliated researcher

PubMed DOI Crossref

Mutations in FLVCR2 associated with Fowler syndrome and survival beyond infancy.

Kvarnung M, Taylan F, Nilsson D, ..., Nordgren A, Syk Lundberg E

Clin. Genet. 89 (1) 99-103 [2016-01-00; online 2015-03-04]

Affiliated researcher

DOI Crossref

Large-scale non-targeted metabolomic profiling in three human population-based studies

Ganna A, Fall T, Salihovic S, ..., Pawitan Y, Ingelsson E

Metabolomics 12 (1) - [2016-01-00; online 2015-11-07]

Affiliated researcher

PubMed DOI Crossref

Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells.

Stäubert C, Krakowsky R, Bhuiyan H, ..., Broom O, Nordström A

Med. Oncol. 33 (1) 6 [2016-01-00; online 2015-12-23]

Affiliated researcher

PubMed DOI Crossref

Genomic signature of successful colonization of Eurasia by the allopolyploid shepherd's purse (Capsella bursa-pastoris).

Cornille A, Salcedo A, Kryvokhyzha D, ..., Wright SI, Lascoux M

Mol. Ecol. 25 (2) 616-629 [2016-01-00; online 2016-01-20]

Affiliated researcher

PubMed DOI Crossref

Genetic heterogeneity in rhabdomyosarcoma revealed by SNP array analysis.

Walther C, Mayrhofer M, Nilsson J, ..., Gisselsson D, Mertens F

Genes Chromosomes Cancer 55 (1) 3-15 [2016-01-00; online 2015-10-20]

Affiliated researcher

PubMed DOI Crossref

F11 is associated with recurrent VTE in women. A prospective cohort study.

Bruzelius M, Ljungqvist M, Bottai M, ..., Lärfars G, Odeberg J

Thromb. Haemost. 115 (2) 406-414 [2016-01-00; online 2015-10-01]

Affiliated researcher

PubMed DOI Crossref

Exome and genome sequencing: a revolution for the discovery and diagnosis of monogenic disorders.

Stranneheim H, Wedell A

J. Intern. Med. 279 (1) 3-15 [2016-01-00; online 2015-08-07]

Affiliated researcher

PubMed DOI Crossref

Concentrations of antibiotics predicted to select for resistant bacteria: Proposed limits for environmental regulation.

Bengtsson-Palme J, Larsson DG

Environ Int 86 (-) 140-149 [2016-01-00; online 2015-11-17]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Composition of human faecal microbiota in resistance to Campylobacter infection.

Kampmann C, Dicksved J, Engstrand L, Rautelin H

Clin. Microbiol. Infect. 22 (1) 61.e1-61.e8 [2016-01-00; online 2015-09-11]

Affiliated researcher

PubMed DOI Crossref

Cerebrospinal fluid kynurenines in multiple sclerosis; relation to disease course and neurocognitive symptoms.

Aeinehband S, Brenner P, Ståhl S, ..., Erhardt S, Piehl F

Brain Behav. Immun. 51 (-) 47-55 [2016-01-00; online 2015-07-17]

Affiliated researcher

PubMed DOI Crossref

A minimalistic microbial food web in an excavated deep subsurface clay rock.

Bagnoud A, de Bruijn I, Andersson AF, ..., Schwyn B, Bernier-Latmani R

FEMS Microbiol. Ecol. 92 (1) - [2016-01-00; online 2015-11-04]

Affiliated researcher

PubMed DOI Crossref

A critical role for ATF2 transcription factor in the regulation of E-selectin expression in response to non-endotoxin components of Neisseria meningitidis.

Jacobsen MC, Dusart PJ, Kotowicz K, ..., Klein NJ, Dixon GL

Cell. Microbiol. 18 (1) 66-79 [2016-01-00; online 2015-07-31]

Affiliated researcher

PubMed DOI Crossref

A comprehensive comparative review of sequence-based predictors of DNA- and RNA-binding residues.

Yan J, Friedrich S, Kurgan L

Brief. Bioinformatics 17 (1) 88-105 [2016-01-00; online 2015-05-01]

Affiliated researcher

DOI Crossref

Simultaneous quantification of imatinib and CGP74588 in human plasma by liquid chromatography-time of flight mass spectrometry (LC-TOF-MS)

Ubhayasekera SJKA, Aluthgedara W, Ek B, Bergquist J

Anal. Methods 8 (15) 3046-3054 [2016-00-00; online 2016-00-00]

Affiliated researcher

DOI Crossref

Organocatalyzed Mannich reactions on minocycline: Towards novel tetracycline antibiotics

CHIWUNZE TE, Azumah R, Ramtahal M, ..., Govender T, Naicker T

S.Afr.j.chem. 69 (-) - [2016-00-00; online 2016-00-00]

Affiliated researcher

DOI Crossref

Highly scalable production of uniformly-coated superparamagnetic nanoparticles for triggered drug release from alginate hydrogels

Teleki A, Haufe FL, Hirt AM, Pratsinis SE, Sotiriou GA

RSC Adv. 6 (26) 21503-21510 [2016-00-00; online 2016-00-00]

Alexandra Teleki SciLifeLab Fellow

DOI Crossref

Fractal Dimension versus Process Complexity

Joosten JJ, Soler-Toscano F, Zenil H

Advances in Mathematical Physics 2016 (-) 1-21 [2016-00-00; online 2016-00-00]

Affiliated researcher

DOI Crossref

Formation of hierarchical bone-like apatites on silk microfiber templates via biomineralization

Xu Z, Shi L, Hu D, ..., Yang M, Zhu L

RSC Adv. 6 (80) 76426-76433 [2016-00-00; online 2016-00-00]

Affiliated researcher

DOI Crossref

Bridging Histology and Bioinformatics—Computational Analysis of Spatially Resolved Transcriptomics

Mignardi M, Ishaq O, Qian X, Wahlby C

Proc. IEEE - (-) 1-12 [2016-00-00; online 2016-00-00]

Affiliated researcher

PubMed DOI Crossref

Systematic hierarchical coarse-graining with the inverse Monte Carlo method.

Lyubartsev AP, Naômé A, Vercauteren DP, Laaksonen A

J Chem Phys 143 (24) 243120 [2015-12-28; online 2016-01-03]

Affiliated researcher

DOI Crossref

Effect of tunable dot charging on photoresponse spectra of GaAs p-i-n diode with InAs quantum dots

Shang X, Yu Y, Li M, ..., Fu Y, Niu Z

Journal of Applied Physics 118 (24) 244503 [2015-12-28; online 2015-12-30]

Affiliated researcher

PubMed DOI Crossref

Fragment-Based Discovery of Subtype-Selective Adenosine Receptor Ligands from Homology Models.

Ranganathan A, Stoddart LA, Hill SJ, Carlsson J

J Med Chem 58 (24) 9578-9590 [2015-12-24; online 2015-12-08]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Evaluation of Intracellular Signaling Downstream Chimeric Antigen Receptors.

Karlsson H, Svensson E, Gigg C, ..., Dotti G, Loskog A

PLoS ONE 10 (12) e0144787 [2015-12-23; online 2015-12-23]

Affiliated researcher

PubMed DOI Crossref

p21-activated kinase group II small compound inhibitor GNE-2861 perturbs estrogen receptor alpha signaling and restores tamoxifen-sensitivity in breast cancer cells.

Zhuang T, Zhu J, Li Z, ..., Dahlman-Wright K, Strömblad S

Oncotarget 6 (41) 43853-43868 [2015-12-22; online 2015-11-12]

Affiliated researcher

PubMed DOI Crossref

The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling.

Habuka M, Fagerberg L, Hallström BM, ..., Yamamoto T, Uhlen M

PLoS ONE 10 (12) e0145301 [2015-12-22; online 2015-12-22]

Affiliated researcher

PubMed DOI Crossref

Transcriptome analysis reveals mucin 4 to be highly associated with periodontitis and identifies pleckstrin as a link to systemic diseases.

Lundmark A, Davanian H, Båge T, ..., Lundeberg J, Yucel-Lindberg T

Sci Rep 5 (-) 18475 [2015-12-21; online 2015-12-21]

Affiliated researcher

PubMed DOI Crossref

Genome-wide genetic homogeneity between sexes and populations for human height and body mass index.

Yang J, Bakshi A, Zhu Z, ..., Ingelsson E, Visscher PM

Hum. Mol. Genet. 24 (25) 7445-7449 [2015-12-20; online 2015-10-22]

Affiliated researcher

PubMed DOI Crossref

Naturally Occurring Adrenocortical Insufficiency--An Epidemiological Study Based on a Swedish-Insured Dog Population of 525,028 Dogs.

Hanson JM, Tengvall K, Bonnett BN, Hedhammar Å

J. Vet. Intern. Med. 30 (1) 76-84 [2015-12-18; online 2015-12-18]

Affiliated researcher

PubMed DOI Crossref

Exploring water as building bricks in enzyme engineering.

Hendil-Forssell P, Martinelle M, Syrén PO

Chem. Commun. (Camb.) 51 (97) 17221-17224 [2015-12-18; online 2015-10-02]

Affiliated researcher

PubMed DOI Crossref

Cancer Metabolism: A Modeling Perspective.

Ghaffari P, Mardinoglu A, Nielsen J

Front. Physiol. 6 (-) 382 [2015-12-16; online 2015-12-16]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Oligonucleotide gap-fill ligation for mutation detection and sequencing in situ.

Mignardi M, Mezger A, Qian X, ..., Larsson C, Nilsson M

Nucleic Acids Res. 43 (22) e151 [2015-12-15; online 2015-08-03]

Affiliated researcher

PubMed DOI Crossref

Litomosoides sigmodontis: a jird urine metabolome study.

Globisch D, Specht S, Pfarr KM, ..., Hoerauf A, Janda KD

Bioorg. Med. Chem. Lett. 25 (24) 5804-5807 [2015-12-15; online 2015-10-23]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Metagenome-assembled genomes uncover a global brackish microbiome.

Hugerth LW, Larsson J, Alneberg J, ..., Pinhassi J, Andersson AF

Genome Biol. 16 (-) 279 [2015-12-14; online 2015-12-14]

Affiliated researcher DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Application of Gene Expression Trajectories Initiated from ErbB Receptor Activation Highlights the Dynamics of Divergent Promoter Usage.

Carbajo D, Magi S, Itoh M, ..., Okada-Hatakeyama M, Mar JC

PLoS ONE 10 (12) e0144176 [2015-12-14; online 2015-12-14]

Affiliated researcher

PubMed DOI Crossref

Metagenome-Based Metabolic Reconstruction Reveals the Ecophysiological Function of Epsilonproteobacteria in a Hydrocarbon-Contaminated Sulfidic Aquifer.

Keller AH, Schleinitz KM, Starke R, ..., Vogt C, Kleinsteuber S

Front Microbiol 6 (-) 1396 [2015-12-10; online 2015-12-10]

Affiliated researcher

PubMed DOI Crossref

Hydrogen production by the engineered cyanobacterial strain Nostoc PCC 7120 ΔhupW examined in a flat panel photobioreactor system.

Nyberg M, Heidorn T, Lindblad P

J. Biotechnol. 215 (-) 35-43 [2015-12-10; online 2015-08-29]

Affiliated researcher

PubMed DOI Crossref

High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes.

Dijksterhuis JP, Arthofer E, Marinescu VD, ..., Mulder J, Schulte G

Exp. Cell Res. 339 (2) 280-288 [2015-12-10; online 2015-10-25]

Affiliated researcher

PubMed DOI Crossref

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Zhang L, Kundu S, Feenstra T, ..., Dieterich LC, Dimberg A

Sci Signal 8 (406) ra125 [2015-12-08; online 2015-12-08]

Affiliated researcher

PubMed DOI Crossref

Effect of voluntary alcohol consumption on Maoa expression in the mesocorticolimbic brain of adult male rats previously exposed to prolonged maternal separation.

Bendre M, Comasco E, Nylander I, Nilsson KW

Transl Psychiatry 5 (12) e690 [2015-12-08; online 2015-12-08]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Tumor-Induced Local and Systemic Impact on Blood Vessel Function.

Cedervall J, Dimberg A, Olsson AK

Mediators Inflamm. 2015 (-) 418290 [2015-12-07; online 2015-12-07]

Affiliated researcher

PubMed DOI Crossref

Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders.

Hofmann-Apitius M, Ball G, Gebel S, ..., Tegnér J, Canard L

Int J Mol Sci 16 (12) 29179-29206 [2015-12-07; online 2015-12-07]

Affiliated researcher

PubMed DOI Crossref

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation.

Soler Artigas M, Wain LV, Miller S, ..., Hall IP, Tobin MD

Nat Commun 6 (-) 8658 [2015-12-04; online 2015-12-04]

Affiliated researcher

PubMed DOI Crossref

Multipotent versus differentiated cell fate selection in the developing Drosophila airways.

Matsuda R, Hosono C, Samakovlis C, Saigo K

Elife 4 (-) - [2015-12-02; online 2015-12-02]

Affiliated researcher

PubMed DOI Crossref

cgmisc: enhanced genome-wide association analyses and visualization.

Kierczak M, Jabłońska J, Forsberg SK, ..., Carlborg Ö, Lindblad-Toh K

Bioinformatics 31 (23) 3830-3831 [2015-12-01; online 2015-08-06]

Affiliated researcher

PubMed DOI Crossref

Stratification of Hepatocellular Carcinoma Patients Based on Acetate Utilization.

Björnson E, Mukhopadhyay B, Asplund A, ..., Nielsen J, Mardinoglu A

Cell Reports 13 (9) 2014-2026 [2015-12-01; online 2015-11-19]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Rapid and Efficient Conversion of (11) CO2 to (11) CO through Silacarboxylic Acids: Applications in Pd-Mediated Carbonylations.

Nordeman P, Friis SD, Andersen TL, ..., Skrydstrup T, Antoni G

Chemistry 21 (49) 17601-17604 [2015-12-01; online 2015-10-23]

Affiliated researcher

PubMed DOI Crossref

Protein profiling reveals consequences of lifestyle choices on predicted biological aging.

Enroth S, Enroth SB, Johansson Å, Gyllensten U

Sci Rep 5 (-) 17282 [2015-12-01; online 2015-12-01]

Affiliated researcher

PubMed DOI Crossref

Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration.

Roberts TC, Johansson HJ, McClorey G, ..., El Andaloussi S, Wood MJ

Hum. Mol. Genet. 24 (23) 6756-6768 [2015-12-01; online 2015-09-18]

Affiliated researcher

DOI Crossref

Magnetic nanobeads present during enzymatic amplification and labeling for a simplified DNA detection protocol based on AC susceptometry

Bejhed RS, Strømme M, Svedlindh P, Ahlford A, Strömberg M

AIP Advances 5 (12) 127139 [2015-12-01; online 2015-12-31]

Affiliated researcher

PubMed DOI Crossref

Highly Sensitive FRET-FCS Detects Amyloid β-Peptide Oligomers in Solution at Physiological Concentrations.

Wennmalm S, Chmyrov V, Widengren J, Tjernberg L

Anal. Chem. 87 (23) 11700-11705 [2015-12-01; online 2015-11-10]

Affiliated researcher

PubMed DOI Crossref

Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity.

Hägg S, Ganna A, Van Der Laan SW, ..., Pawitan Y, Ingelsson E

Hum. Mol. Genet. 24 (23) 6849-6860 [2015-12-01; online 2015-09-16]

Affiliated researcher

PubMed DOI Crossref

Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy.

Gineste C, Hernandez A, Ivarsson N, ..., Wredenberg A, Westerblad H

Hum. Mol. Genet. 24 (23) 6580-6587 [2015-12-01; online 2015-09-14]

Affiliated researcher

PubMed DOI Crossref

ARResT/AssignSubsets: a novel application for robust subclassification of chronic lymphocytic leukemia based on B cell receptor IG stereotypy.

Bystry V, Agathangelidis A, Bikos V, ..., Darzentas N, European Research Initiative on CLL

Bioinformatics 31 (23) 3844-3846 [2015-12-01; online 2015-08-06]

Affiliated researcher

PubMed DOI Crossref

A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair.

Herr P, Lundin C, Evers B, ..., Sonnhammer E, Helleday T

Cell Discov 1 (-) 15034 [2015-12-01; online 2015-12-01]

Affiliated researcher

PubMed DOI Crossref

The body mass index (BMI) is significantly correlated with levels of cytokines and chemokines in cerebrospinal fluid.

Larsson A, Carlsson L, Lind AL, ..., Kamali-Moghaddam M, Thulin M

Cytokine 76 (2) 514-518 [2015-12-00; online 2015-07-15]

Affiliated researcher

DOI Crossref

The European technical report on aquatic effect-based monitoring tools under the water framework directive

Wernersson AS, Carere M, Maggi C, ..., Kammann U, Kase R

Environ Sci Eur 27 (1) - [2015-12-00; online 2015-03-11]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

The Constrained Maximal Expression Level Owing to Haploidy Shapes Gene Content on the Mammalian X Chromosome.

Hurst LD, Ghanbarian AT, Forrest AR, FANTOM consortium , Huminiecki L

PLoS Biol. 13 (12) e1002315 [2015-12-00; online 2015-12-18]

Affiliated researcher

PubMed DOI Crossref

The Cannabinoid Receptor-1 Is an Imaging Biomarker of Brown Adipose Tissue.

Eriksson O, Mikkola K, Espes D, ..., Solin O, Nuutila P

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 56 (12) 1937-1941 [2015-12-00; online 2015-09-10]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2.

Carthy JM, Sundqvist A, Heldin A, ..., Heldin CH, Moustakas A

J. Cell. Physiol. 230 (12) 3084-3092 [2015-12-00; online 2015-06-23]

Affiliated researcher

PubMed DOI Crossref

Susceptibility to infections, without concomitant hyper-IgE, reported in 1976, is caused by hypomorphic mutation in the phosphoglucomutase 3 (PGM3) gene.

Lundin KE, Hamasy A, Backe PH, ..., Stenmark S, Smith CI

Clin. Immunol. 161 (2) 366-372 [2015-12-00; online 2015-10-19]

Affiliated researcher

PubMed DOI Crossref

Psychiatric symptoms in adolescents: FKBP5 genotype--early life adversity interaction effects.

Comasco E, Gustafsson PA, Sydsjö G, ..., Aho N, Svedin CG

Eur Child Adolesc Psychiatry 24 (12) 1473-1483 [2015-12-00; online 2015-09-30]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Phenotypic expansion of visceral myopathy associated with ACTG2 tandem base substitution.

Klar J, Raykova D, Gustafson E, ..., Wanders A, Dahl N

Eur. J. Hum. Genet. 23 (12) 1679-1683 [2015-12-00; online 2015-03-18]

Affiliated researcher

PubMed DOI Crossref

Molecular Cloning and Biochemical Characterization of the Iron Superoxide Dismutase from the Cyanobacterium Nostoc punctiforme ATCC 29133 and Its Response to Methyl Viologen-Induced Oxidative Stress.

Moirangthem LD, Ibrahim KS, Vanlalsangi R, ..., Lindblad P, Bhattacharya J

Mol. Biotechnol. 57 (11-12) 1003-1009 [2015-12-00; online 2015-10-07]

Affiliated researcher

PubMed DOI Crossref

Metagenomic insights into strategies of aerobic and anaerobic carbon and nitrogen transformation in boreal lakes

Peura S, Sinclair L, Bertilsson S, Eiler A

Sci Rep 5 (1) - [2015-12-00; online 2015-07-10]

Affiliated researcher Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) for analysis of endogenous steroids in the luteal phase and early pregnancy in dogs: a pilot study.

Holst BS, Kushnir MM, Bergquist J

Vet Clin Pathol 44 (4) 552-558 [2015-12-00; online 2015-11-23]

Affiliated researcher

PubMed DOI Crossref

Hypercompetition in biomedical research evaluation and its impact on young scientist careers.

Kamerlin SC

Int. Microbiol. 18 (4) 253-261 [2015-12-00; online 2016-09-10]

Affiliated researcher

PubMed DOI Crossref

Hormone Replacement Therapy Associated White Blood Cell DNA Methylation and Gene Expression are Associated With Within-Pair Differences of Body Adiposity and Bone Mass.

Bahl A, Pöllänen E, Ismail K, ..., Kovanen V, Ollikainen M

Twin Res Hum Genet 18 (6) 647-661 [2015-12-00; online 2015-12-19]

Affiliated researcher

PubMed DOI Crossref

Gout and its comorbidities in the total population of Stockholm.

Wändell P, Carlsson AC, Ljunggren G

Prev Med 81 (-) 387-391 [2015-12-00; online 2015-10-21]

Affiliated researcher

PubMed DOI Crossref

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

Gaulton KJ, Ferreira T, Lee Y, ..., Morris AP, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium

Nat. Genet. 47 (12) 1415-1425 [2015-12-00; online 2015-11-09]

Affiliated researcher

PubMed DOI Crossref

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

Bentham J, Morris DL, Graham DSC, ..., Alarcón-Riquelme ME, Vyse TJ

Nat. Genet. 47 (12) 1457-1464 [2015-12-00; online 2015-10-26]

Affiliated researcher

PubMed DOI Crossref

Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies.

Albrecht I, Wick C, Hallgren Å, ..., Kämpe O, Lundberg IE

J. Clin. Invest. 125 (12) 4612-4624 [2015-12-00; online 2015-11-09]

Affiliated researcher

PubMed DOI Crossref

Daily self-sampling for high-risk human papillomavirus (HR-HPV) testing.

Sanner K, Wikström I, Gustavsson I, ..., Gyllensten U, Olovsson M

J. Clin. Virol. 73 (-) 1-7 [2015-12-00; online 2015-10-08]

Affiliated researcher

PubMed DOI Crossref

Classification of Amino Acid Substitutions in Mismatch Repair Proteins Using PON-MMR2.

Niroula A, Vihinen M

Hum. Mutat. 36 (12) 1128-1134 [2015-12-00; online 2015-09-22]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides

Gosselin-Badaroudine P, Moreau A, Delemotte L, ..., Klein ML, Chahine M

Sci Rep 5 (1) - [2015-12-00; online 2015-07-23]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Bacterial diversity along a 2600 km river continuum.

Savio D, Sinclair L, Ijaz UZ, ..., Farnleitner AH, Eiler A

Environ. Microbiol. 17 (12) 4994-5007 [2015-12-00; online 2015-06-11]

Affiliated researcher

PubMed DOI Crossref

Alteration by p11 of mGluR5 localization regulates depression-like behaviors.

Lee KW, Westin L, Kim J, ..., Kim Y, Greengard P

Mol. Psychiatry 20 (12) 1546-1556 [2015-12-00; online 2015-09-15]

Affiliated researcher

PubMed DOI Crossref

De novo assembly of Dekkera bruxellensis: a multi technology approach using short and long-read sequencing and optical mapping.

Olsen RA, Bunikis I, Tiukova I, ..., Käller M, Vezzi F

Gigascience 4 (-) 56 [2015-11-26; online 2015-11-26]

Affiliated researcher

PubMed DOI Crossref

Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome.

Eakins R, Walsh J, Randle L, ..., Goldring CE, Park BK

Sci Rep 5 (-) 16423 [2015-11-26; online 2015-11-26]

Affiliated researcher

PubMed DOI Crossref

Single-cell screening of photosynthetic growth and lactate production by cyanobacteria.

Hammar P, Angermayr SA, Sjostrom SL, ..., Hudson EP, Joensson HN

Biotechnol Biofuels 8 (1) 193 [2015-11-25; online 2015-11-25]

Affiliated researcher Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

Machine Learning Based Classification of Microsatellite Variation: An Effective Approach for Phylogeographic Characterization of Olive Populations.

Torkzaban B, Kayvanjoo AH, Ardalan A, ..., Ebrahimi M, Hosseini-Mazinani M

PLoS ONE 10 (11) e0143465 [2015-11-24; online 2015-11-24]

Affiliated researcher

PubMed DOI Crossref

Genome-Wide Association Study Identifies That the ABO Blood Group System Influences Interleukin-10 Levels and the Risk of Clinical Events in Patients with Acute Coronary Syndrome.

Johansson Å, Alfredsson J, Eriksson N, Wallentin L, Siegbahn A

PLoS ONE 10 (11) e0142518 [2015-11-24; online 2015-11-24]

Affiliated researcher

PubMed DOI Crossref

Amelanism in the corn snake is associated with the insertion of an LTR-retrotransposon in the OCA2 gene.

Saenko SV, Lamichhaney S, Martinez Barrio A, ..., Andersson L, Milinkovitch MC

Sci Rep 5 (-) 17118 [2015-11-24; online 2015-11-24]

Affiliated researcher

PubMed DOI Crossref

Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification.

Vanlandewijck M, Lebouvier T, Andaloussi Mäe M, ..., Keller A, Betsholtz C

PLoS ONE 10 (11) e0143407 [2015-11-23; online 2015-11-23]

Affiliated researcher

PubMed DOI Crossref

Kinetic Studies to Elucidate Impaired Metabolism of Triglyceride-rich Lipoproteins in Humans.

Adiels M, Mardinoglu A, Taskinen MR, Borén J

Front. Physiol. 6 (-) 342 [2015-11-20; online 2015-11-20]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

RNA sequencing uncovers antisense RNAs and novel small RNAs in Streptococcus pyogenes.

Le Rhun A, Beer YY, Reimegård J, Chylinski K, Charpentier E

RNA Biol 13 (2) 177-195 [2015-11-19; online 2015-11-19]

Affiliated researcher

PubMed DOI Crossref

Jagged 1 Rescues the Duchenne Muscular Dystrophy Phenotype.

Vieira NM, Elvers I, Alexander MS, ..., Kunkel LM, Zatz M

Cell 163 (5) 1204-1213 [2015-11-19; online 2015-11-12]

Affiliated researcher

PubMed DOI Crossref

Co-occurrence of resistance genes to antibiotics, biocides and metals reveals novel insights into their co-selection potential.

Pal C, Bengtsson-Palme J, Kristiansson E, Larsson DG

BMC Genomics 16 (-) 964 [2015-11-17; online 2015-11-17]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Single cell analysis of cancer cells using an improved RT-MLPA method has potential for cancer diagnosis and monitoring.

Kvastad L, Werne Solnestam B, Johansson E, ..., Latta D, Lundeberg J

Sci Rep 5 (-) 16519 [2015-11-12; online 2015-11-12]

Affiliated researcher Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

NPM1 histone chaperone is upregulated in glioblastoma to promote cell survival and maintain nucleolar shape.

Holmberg Olausson K, Elsir T, Moazemi Goudarzi K, Nistér M, Lindström MS

Sci Rep 5 (-) 16495 [2015-11-12; online 2015-11-12]

Affiliated researcher

DOI Crossref

The 2015 super-resolution microscopy roadmap

Hell SW, Sahl SJ, Bates M, ..., Diaspro A, Cordes T

J. Phys. D: Appl. Phys. 48 (44) 443001 [2015-11-11; online 2015-10-15]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Immunocapture strategies in translational proteomics.

Fredolini C, Byström S, Pin E, ..., Nilsson P, Schwenk JM

Expert Rev Proteomics 13 (1) 83-98 [2015-11-11; online 2015-11-11]

Affiliated researcher

PubMed DOI Crossref

A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases.

Gustafsson M, Gawel DR, Alfredsson L, ..., Nestor CE, Benson M

Sci Transl Med 7 (313) 313ra178 [2015-11-11; online 2015-11-13]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies.

Patalano S, Vlasova A, Wyatt C, ..., Reik W, Sumner S

Proc. Natl. Acad. Sci. U.S.A. 112 (45) 13970-13975 [2015-11-10; online 2015-10-19]

Affiliated researcher

PubMed DOI Crossref

Generalized Born and Explicit Solvent Models for Free Energy Calculations in Organic Solvents: Cyclodextrin Dimerization.

Zhang H, Tan T, van der Spoel D

J Chem Theory Comput 11 (11) 5103-5113 [2015-11-10; online 2015-10-08]

Affiliated researcher

PubMed DOI Crossref

Flow-through cross-polarized imaging as a new tool to overcome the analytical sensitivity challenges of a low-dose crystalline compound in a lipid matrix.

Adler C, Schönenberger M, Teleki A, Leuenberger B, Kuentz M

J Pharm Biomed Anal 115 (-) 20-30 [2015-11-10; online 2015-06-24]

Alexandra Teleki SciLifeLab Fellow

PubMed DOI Crossref

Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response.

Xing M, Wang X, Palmai-Pallag T, ..., Hickson ID, Ying S

Oncotarget 6 (35) 37638-37646 [2015-11-10; online 2015-09-29]

Affiliated researcher

PubMed DOI Crossref

Effect of genetic and environmental factors on protein biomarkers for common non-communicable disease and use of personally normalized plasma protein profiles (PNPPP).

Enroth S, Bosdotter Enroth S, Johansson Å, Gyllensten U

Biomarkers 20 (6-7) 355-364 [2015-11-09; online 2015-11-09]

Affiliated researcher

PubMed DOI Crossref

Mechanisms of fluorescence decays of colloidal CdSe-CdS/ZnS quantum dots unraveled by time-resolved fluorescence measurement.

Xu H, Chmyrov V, Widengren J, Brismar H, Fu Y

Phys Chem Chem Phys 17 (41) 27588-27595 [2015-11-07; online 2015-10-02]

Affiliated researcher

PubMed DOI Crossref

An 8 minute colorimetric paper-based reverse phase vertical flow serum microarray for screening of hyper IgE syndrome.

Reuterswärd P, Gantelius J, Andersson Svahn H

Analyst 140 (21) 7327-7334 [2015-11-07; online 2015-09-15]

Affiliated researcher

PubMed DOI Crossref

Immunostimulatory Gene Therapy Using Oncolytic Viruses as Vehicles.

Loskog A

Viruses 7 (11) 5780-5791 [2015-11-06; online 2015-11-06]

Affiliated researcher

PubMed DOI Crossref

Development of Phage-Based Antibody Fragment Reagents for Affinity Enrichment of Bacterial Immunoglobulin G Binding Proteins.

Säll A, Sjöholm K, Waldemarson S, ..., Persson H, Malmström J

J. Proteome Res. 14 (11) 4704-4713 [2015-11-06; online 2015-10-27]

Affiliated researcher

PubMed DOI Crossref

Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26.

Kishita Y, Pajak A, Bolar NA, ..., Okazaki Y, Wedell A

Am. J. Hum. Genet. 97 (5) 761-768 [2015-11-05; online 2015-10-29]

Affiliated researcher

PubMed DOI Crossref

Castration radiosensitizes prostate cancer tissue by impairing DNA double-strand break repair.

Tarish FL, Schultz N, Tanoglidi A, ..., Granfors T, Helleday T

Sci Transl Med 7 (312) 312re11 [2015-11-04; online 2015-11-06]

Affiliated researcher

PubMed DOI Crossref

VEGF-B-Neuropilin-1 signaling is spatiotemporally indispensable for vascular and neuronal development in zebrafish.

Jensen LD, Nakamura M, Bräutigam L, ..., Samani NJ, Cao Y

Proc. Natl. Acad. Sci. U.S.A. 112 (44) E5944-E5953 [2015-11-03; online 2015-10-19]

Affiliated researcher

PubMed DOI Crossref

NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity.

Jacome A, Gutierrez-Martinez P, Schiavoni F, ..., Blasco MA, Fernandez-Capetillo O

EMBO J. 34 (21) 2604-2619 [2015-11-03; online 2015-10-06]

Affiliated researcher

PubMed DOI Crossref

Elevated expression of the C-type lectin CD93 in the glioblastoma vasculature regulates cytoskeletal rearrangements that enhance vessel function and reduce host survival.

Langenkamp E, Zhang L, Lugano R, ..., Smits A, Dimberg A

Cancer Res. 75 (21) 4504-4516 [2015-11-01; online 2015-09-11]

Affiliated researcher

PubMed DOI Crossref

Toward the Replacement of Animal Experiments through the Bioinformatics-driven Analysis of 'Omics' Data from Human Cell Cultures.

Grafström RC, Nymark P, Hongisto V, ..., Kaski S, Kohonen P

Altern Lab Anim 43 (5) 325-332 [2015-11-00; online 2015-11-10]

Affiliated researcher

PubMed DOI Crossref

Tissue factor/factor VIIa signalling promotes cytokine-induced beta cell death and impairs glucose-stimulated insulin secretion from human pancreatic islets.

Edén D, Siegbahn A, Mokhtari D

Diabetologia 58 (11) 2563-2572 [2015-11-00; online 2015-08-14]

Affiliated researcher

PubMed DOI Crossref

The ketogenic diet compensates for AGC1 deficiency and improves myelination.

Dahlin M, Martin DA, Hedlund Z, ..., von Döbeln U, Wedell A

Epilepsia 56 (11) e176-e181 [2015-11-00; online 2015-09-24]

Affiliated researcher

PubMed DOI Crossref

The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling.

Zieba A, Sjöstedt E, Olovsson M, ..., Uhlen M, Ponten F

OMICS 19 (11) 659-668 [2015-11-00; online 2015-10-21]

Affiliated researcher

PubMed DOI Crossref

Stage-specific assembly events of the 6-MDa small-subunit processome initiate eukaryotic ribosome biogenesis.

Chaker-Margot M, Hunziker M, Barandun J, Dill BD, Klinge S

Nat. Struct. Mol. Biol. 22 (11) 920-923 [2015-11-00; online 2015-10-19]

Jonas Barandun SciLifeLab Fellow

PubMed DOI Crossref

Slow degradation in phagocytic astrocytes can be enhanced by lysosomal acidification.

Lööv C, Mitchell CH, Simonsson M, Erlandsson A

Glia 63 (11) 1997-2009 [2015-11-00; online 2015-06-12]

Affiliated researcher

PubMed DOI Crossref

Single-cell genomics of a rare environmental alphaproteobacterium provides unique insights into Rickettsiaceae evolution.

Martijn J, Schulz F, Zaremba-Niedzwiedzka K, ..., Guy L, Ettema TJ

ISME J 9 (11) 2373-2385 [2015-11-00; online 2015-04-07]

Affiliated researcher

PubMed DOI Crossref

Single-Molecule Sequencing Reveals Estrogen-Regulated Clinically Relevant lncRNAs in Breast Cancer.

Jonsson P, Coarfa C, Mesmar F, ..., Gunaratne PH, Williams C

Mol. Endocrinol. 29 (11) 1634-1645 [2015-11-00; online 2015-10-01]

Affiliated researcher

PubMed DOI Crossref

Risks and benefits of sex-mismatched hematopoietic cell transplantation differ according to conditioning strategy.

Nakasone H, Remberger M, Tian L, ..., Miklos DB, Meyer E

Haematologica 100 (11) 1477-1485 [2015-11-00; online 2015-08-06]

Affiliated researcher

PubMed DOI Crossref

Rescue of primary ubiquinone deficiency due to a novel COQ7 defect using 2,4-dihydroxybensoic acid.

Freyer C, Stranneheim H, Naess K, ..., Wredenberg A, Wedell A

J. Med. Genet. 52 (11) 779-783 [2015-11-00; online 2015-06-17]

Affiliated researcher

PubMed DOI Crossref

Proteomic Profiling of Detergent Resistant Membranes (Lipid Rafts) of Prostasomes.

Dubois L, Ronquist KK, Ek B, Ronquist G, Larsson A

Mol. Cell Proteomics 14 (11) 3015-3022 [2015-11-00; online 2015-08-13]

Affiliated researcher

PubMed DOI Crossref

Population genetic differentiation of height and body mass index across Europe.

Robinson MR, Hemani G, Medina-Gomez C, ..., Yang J, Visscher PM

Nat. Genet. 47 (11) 1357-1362 [2015-11-00; online 2015-09-14]

Affiliated researcher

PubMed DOI Crossref

Overexpression of functional human oxidosqualene cyclase in Escherichia coli.

Kürten C, Uhlén M, Syrén PO

Protein Expr. Purif. 115 (-) 46-53 [2015-11-00; online 2015-05-08]

Affiliated researcher

PubMed DOI Crossref

Mutation in CEP63 co-segregating with developmental dyslexia in a Swedish family.

Einarsdottir E, Svensson I, Darki F, ..., Kere J, Matsson H

Hum. Genet. 134 (11-12) 1239-1248 [2015-11-00; online 2015-09-23]

Affiliated researcher

PubMed DOI Crossref

METAXA2: improved identification and taxonomic classification of small and large subunit rRNA in metagenomic data.

Bengtsson-Palme J, Hartmann M, Eriksson KM, ..., Larsson DG, Nilsson RH

Mol Ecol Resour 15 (6) 1403-1414 [2015-11-00; online 2015-03-23]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Linked selection and recombination rate variation drive the evolution of the genomic landscape of differentiation across the speciation continuum of Ficedula flycatchers.

Burri R, Nater A, Kawakami T, ..., Török J, Ellegren H

Genome Res. 25 (11) 1656-1665 [2015-11-00; online 2015-09-09]

Affiliated researcher

PubMed DOI Crossref

Larger aggregates of mutant seipin in Celia's Encephalopathy, a new protein misfolding neurodegenerative disease.

Ruiz-Riquelme A, Sánchez-Iglesias S, Rábano A, ..., Araújo-Vilar D, Requena JR

Neurobiol. Dis. 83 (-) 44-53 [2015-11-00; online 2015-08-15]

Affiliated researcher

PubMed DOI Crossref

Integrating Sequence Evolution into Probabilistic Orthology Analysis.

Ullah I, Sjöstrand J, Andersson P, Sennblad B, Lagergren J

Syst. Biol. 64 (6) 969-982 [2015-11-00; online 2015-06-30]

Affiliated researcher

PubMed DOI Crossref

In situ forming interpenetrating hydrogels of hyaluronic acid hybridized with iron oxide nanoparticles.

Kheirabadi M, Shi L, Bagheri R, ..., Hilborn J, Ossipov DA

Biomater Sci 3 (11) 1466-1474 [2015-11-00; online 2015-08-08]

Affiliated researcher

PubMed DOI Crossref

Impact of sludge deposition on biodiversity.

Manzetti S, van der Spoel D

Ecotoxicology 24 (9) 1799-1814 [2015-11-00; online 2015-08-30]

Affiliated researcher

PubMed DOI Crossref

Histidine-domain-containing protein tyrosine phosphatase regulates platelet-derived growth factor receptor intracellular sorting and degradation.

Ma H, Wardega P, Mazaud D, ..., Lennartsson J, Heldin CH

Cell. Signal. 27 (11) 2209-2219 [2015-11-00; online 2015-07-30]

Affiliated researcher

PubMed DOI Crossref

HaloPlex Targeted Resequencing for Mutation Detection in Clinical Formalin-Fixed, Paraffin-Embedded Tumor Samples.

Moens LN, Falk-Sörqvist E, Ljungström V, ..., Nilsson M, Botling J

J Mol Diagn 17 (6) 729-739 [2015-11-00; online 2015-09-03]

Affiliated researcher

PubMed DOI Crossref

Genome-Wide Association Study of Golden Retrievers Identifies Germ-Line Risk Factors Predisposing to Mast Cell Tumours.

Arendt ML, Melin M, Tonomura N, ..., Starkey M, Lindblad-Toh K

PLoS Genet 11 (11) e1005647 [2015-11-00; online 2015-11-20]

Affiliated researcher

PubMed DOI Crossref

Functional characterization of zebrafish cytochrome P450 1 family proteins expressed in yeast.

Stegeman JJ, Behrendt L, Woodin BR, ..., Goldstone JV, Urban P

Biochim. Biophys. Acta 1850 (11) 2340-2352 [2015-11-00; online 2015-07-29]

Lars Behrendt SciLifeLab Fellow

PubMed DOI Crossref

Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background.

Elvers I, Turner-Maier J, Swofford R, ..., Lindblad-Toh K, Alföldi J

Genome Res. 25 (11) 1634-1645 [2015-11-00; online 2015-09-16]

Affiliated researcher

DOI Crossref

Electric vehicle battery technologies: From present state to future systems

Manzetti S, Mariasiu F

Renewable and Sustainable Energy Reviews 51 (-) 1004-1012 [2015-11-00; online 2015-11-00]

Affiliated researcher

PubMed DOI Crossref

Early Exposure to Dogs and Farm Animals and the Risk of Childhood Asthma.

Fall T, Lundholm C, Örtqvist AK, ..., Ingelsson E, Almqvist C

JAMA Pediatr 169 (11) e153219 [2015-11-00; online 2015-11-02]

Affiliated researcher

PubMed DOI Crossref

Concurrent DNA Copy-Number Alterations and Mutations in Genes Related to Maintenance of Genome Stability in Uninvolved Mammary Glandular Tissue from Breast Cancer Patients.

Ronowicz A, Janaszak-Jasiecka A, Skokowski J, ..., Dumanski JP, Piotrowski A

Hum. Mutat. 36 (11) 1088-1099 [2015-11-00; online 2015-08-14]

Affiliated researcher

PubMed DOI Crossref

Assessing the consistency of public human tissue RNA-seq data sets.

Danielsson F, James T, Gomez-Cabrero D, Huss M

Brief. Bioinformatics 16 (6) 941-949 [2015-11-00; online 2015-03-30]

Affiliated researcher

PubMed DOI Crossref

Aberrant splicing of genes involved in haemoglobin synthesis and impaired terminal erythroid maturation in SF3B1 mutated refractory anaemia with ring sideroblasts.

Conte S, Katayama S, Vesterlund L, ..., Kere J, Hellström-Lindberg E

Br. J. Haematol. 171 (4) 478-490 [2015-11-00; online 2015-08-10]

Affiliated researcher

PubMed DOI Crossref

A study of genetic polymorphisms in mitochondrial DNA hypervariable regions I and II of the five major ethnic groups and Vedda population in Sri Lanka.

Ranasinghe R, Tennekoon KH, Karunanayake EH, Lembring M, Allen M

Leg Med (Tokyo) 17 (6) 539-546 [2015-11-00; online 2015-05-27]

Affiliated researcher

PubMed DOI Crossref

Metagenomic sequencing of marine periphyton: taxonomic and functional insights into biofilm communities.

Sanli K, Bengtsson-Palme J, Nilsson RH, ..., Blanck H, Eriksson KM

Front Microbiol 6 (-) 1192 [2015-10-30; online 2015-10-30]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Identification of proteins highly expressed in uterine fluid from mice with hydrometra.

Antonson P, Nalvarte I, Varshney M, ..., Gustafsson JÅ, Dahlman-Wright K

Biochem. Biophys. Res. Commun. 466 (4) 650-655 [2015-10-30; online 2015-09-21]

Affiliated researcher

PubMed DOI Crossref

CytoSpectre: a tool for spectral analysis of oriented structures on cellular and subcellular levels.

Kartasalo K, Pölönen R, Ojala M, ..., Aalto-Setälä K, Kallio P

BMC Bioinformatics 16 (-) 344 [2015-10-26; online 2015-10-26]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Crosstalk between Hippo and TGFβ: Subcellular Localization of YAP/TAZ/Smad Complexes.

Grannas K, Arngården L, Lönn P, ..., Zieba A, Söderberg O

J. Mol. Biol. 427 (21) 3407-3415 [2015-10-23; online 2015-05-01]

Affiliated researcher

PubMed DOI Crossref

Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans.

Massena S, Christoffersson G, Vågesjö E, ..., Kreuger J, Phillipson M

Blood 126 (17) 2016-2026 [2015-10-22; online 2015-08-18]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

The effect of N-methylation of amino acids (Ac-X-OMe) on solubility and conformation: a DFT study.

Md Abdur Rauf S, Arvidsson PI, Albericio F, ..., Kruger HG, Honarparvar B

Org. Biomol. Chem. 13 (39) 9993-10006 [2015-10-21; online 2015-08-21]

Affiliated researcher

PubMed DOI Crossref

Genetic Polymorphisms in Vitamin D Metabolism and Signaling Genes and Risk of Breast Cancer: A Nested Case-Control Study.

Clendenen TV, Ge W, Koenig KL, ..., Sund M, Zeleniuch-Jacquotte A

PLoS ONE 10 (10) e0140478 [2015-10-21; online 2015-10-21]

Affiliated researcher

PubMed DOI Crossref

CGGBP1--an indispensable protein with ubiquitous cytoprotective functions.

Singh U, Westermark B

Ups. J. Med. Sci. 120 (4) 219-232 [2015-10-21; online 2015-10-21]

Affiliated researcher

PubMed DOI Crossref

Biotin-Genomic Run-On (Bio-GRO): A High-Resolution Method for the Analysis of Nascent Transcription in Yeast.

Jordán-Pla A, Miguel A, Serna E, Pelechano V, Pérez-Ortín JE

Methods in molecular biology (Clifton, N.J.) 1361 (-) 125-139 [2015-10-21; online 2015-10-21]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Structure-activity relationships for lipoprotein lipase agonists that lower plasma triglycerides in vivo.

Caraballo R, Larsson M, Nilsson SK, ..., Enquist PA, Elofsson M

Eur J Med Chem 103 (-) 191-209 [2015-10-20; online 2015-09-02]

Affiliated researcher

PubMed DOI Crossref

Induction of USP17 by combining BET and HDAC inhibitors in breast cancer cells.

Borbely G, Haldosen LA, Dahlman-Wright K, Zhao C

Oncotarget 6 (32) 33623-33635 [2015-10-20; online 2015-09-18]

Affiliated researcher

PubMed DOI Crossref

Controlled Lateral Positioning of Microparticles Inside Droplets Using Acoustophoresis.

Fornell A, Nilsson J, Jonsson L, ..., Joensson HN, Tenje M

Anal. Chem. 87 (20) 10521-10526 [2015-10-20; online 2015-10-09]

Affiliated researcher

PubMed DOI Crossref

Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor.

Griese JJ, Kositzki R, Schrapers P, ..., Haumann M, Högbom M

J. Biol. Chem. 290 (42) 25254-25272 [2015-10-16; online 2015-08-31]

Affiliated researcher

PubMed DOI Crossref

Genome-Wide Identification of Alternative Polyadenylation Events Using 3'T-Fill.

Wilkening S, Pelechano V, Steinmetz LM

Methods in molecular biology (Clifton, N.J.) 1358 (-) 295-302 [2015-10-16; online 2015-10-16]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Genetic and nutrient modulation of acetyl-CoA levels in Synechocystis for n-butanol production.

Anfelt J, Kaczmarzyk D, Shabestary K, ..., Uhlén M, Hudson EP

Microb Cell Fact 14 (1) 167 [2015-10-16; online 2015-10-16]

Affiliated researcher Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

Domestication Effects on Stress Induced Steroid Secretion and Adrenal Gene Expression in Chickens.

Fallahsharoudi A, de Kock N, Johnsson M, ..., Wright D, Jensen P

Sci Rep 5 (-) 15345 [2015-10-16; online 2015-10-16]

Affiliated researcher

PubMed DOI Crossref

Role of the AMP kinase in cytokine-induced human EndoC-βH1 cell death.

Fred RG, Kappe C, Ameur A, ..., Scharfmann R, Welsh N

Mol. Cell. Endocrinol. 414 (-) 53-63 [2015-10-15; online 2015-07-26]

Affiliated researcher

PubMed DOI Crossref

A straightforward approach for gated STED-FCS to investigate lipid membrane dynamics.

Clausen MP, Sezgin E, Bernardino de la Serna J, ..., Lagerholm BC, Eggeling C

Methods 88 (-) 67-75 [2015-10-15; online 2015-06-27]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Sensing Positive versus Negative Reward Signals through Adenylyl Cyclase-Coupled GPCRs in Direct and Indirect Pathway Striatal Medium Spiny Neurons.

Nair AG, Gutierrez-Arenas O, Eriksson O, Vincent P, Hellgren Kotaleski J

J. Neurosci. 35 (41) 14017-14030 [2015-10-14; online 2015-10-16]

Affiliated researcher

PubMed DOI Crossref

Mutation in NRAS in familial Noonan syndrome--case report and review of the literature.

Ekvall S, Wilbe M, Dahlgren J, ..., Annerén G, Bondeson ML

BMC Med. Genet. 16 (-) 95 [2015-10-14; online 2015-10-14]

Affiliated researcher

PubMed DOI Crossref

The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation.

Gustafsson Sheppard N, Jarl L, Mahadessian D, ..., Jain M, Nilsson R

Sci Rep 5 (-) 15029 [2015-10-13; online 2015-10-13]

Affiliated researcher

PubMed DOI Crossref

A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging.

Su J, Ekman C, Oskolkov N, ..., Rung J, Hansson O

Skelet Muscle 5 (-) 35 [2015-10-09; online 2015-10-09]

Affiliated researcher

PubMed DOI Crossref

Thousands of RAD-seq Loci Fully Resolve the Phylogeny of the Highly Disjunct Arctic-Alpine Genus Diapensia (Diapensiaceae).

Hou Y, Nowak MD, Mirré V, ..., Brochmann C, Popp M

PLoS ONE 10 (10) e0140175 [2015-10-08; online 2015-10-08]

Affiliated researcher

PubMed DOI Crossref

The alternative splicing factor Nova2 regulates vascular development and lumen formation.

Giampietro C, Deflorian G, Gallo S, ..., Dejana E, Ghigna C

Nat Commun 6 (-) 8479 [2015-10-08; online 2015-10-08]

Affiliated researcher

PubMed DOI Crossref

Proteomics Analysis Reveals Distinct Corona Composition on Magnetic Nanoparticles with Different Surface Coatings: Implications for Interactions with Primary Human Macrophages.

Vogt C, Pernemalm M, Kohonen P, ..., Toprak MS, Fadeel B

PLoS ONE 10 (10) e0129008 [2015-10-07; online 2015-10-07]

Affiliated researcher

PubMed DOI Crossref

Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue.

Mardinoglu A, Heiker JT, Gärtner D, ..., Nielsen J, Blüher M

Sci Rep 5 (1) 14841 [2015-10-05; online 2015-10-05]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

An ace-1 gene duplication resorbs the fitness cost associated with resistance in Anopheles gambiae, the main malaria mosquito.

Assogba BS, Djogbénou LS, Milesi P, ..., Labbé P, Weill M

Sci Rep 5 (-) 14529 [2015-10-05; online 2015-10-05]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Gene-pseudogene evolution: a probabilistic approach.

Mahmudi O, Sennblad B, Arvestad L, Nowick K, Lagergren J

BMC Genomics 16 Suppl 10 (-) S12 [2015-10-02; online 2015-10-02]

Affiliated researcher

PubMed DOI Crossref

Expanding the Catalytic Triad in Epoxide Hydrolases and Related Enzymes.

Amrein BA, Bauer P, Duarte F, ..., Widersten M, Kamerlin SC

ACS Catal 5 (10) 5702-5713 [2015-10-02; online 2015-08-17]

Affiliated researcher

PubMed DOI Crossref

Transcriptome Sequencing Reveals PCAT5 as a Novel ERG-Regulated Long Noncoding RNA in Prostate Cancer.

Ylipää A, Kivinummi K, Kohvakka A, ..., Visakorpi T, Nykter M

Cancer Res. 75 (19) 4026-4031 [2015-10-01; online 2015-08-17]

DDLS Fellow Kimmo Kartasalo

PubMed DOI Crossref

Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair.

Xie S, Mortusewicz O, Ma HT, ..., Helleday T, Qian C

Mol. Cell 60 (1) 163-176 [2015-10-01; online 2015-09-03]

Affiliated researcher

PubMed DOI Crossref

Spatiotemporal Heterogeneity Characterizes the Genetic Landscape of Pheochromocytoma and Defines Early Events in Tumorigenesis.

Crona J, Backman S, Maharjan R, ..., Hellman P, Björklund P

Clin. Cancer Res. 21 (19) 4451-4460 [2015-10-01; online 2015-05-19]

Affiliated researcher

PubMed DOI Crossref

Neuropeptide Y family receptors Y1 and Y2 from sea lamprey, Petromyzon marinus.

Xu B, Lagman D, Sundström G, Larhammar D

Gen. Comp. Endocrinol. 222 (-) 106-115 [2015-10-01; online 2015-08-06]

Affiliated researcher

DOI Crossref

Nanoscopy—imaging life at the nanoscale: a Nobel Prize achievement with a bright future

Blom H, Bates M

Phys. Scr. 90 (10) 108010 [2015-10-01; online 2015-09-22]

Affiliated researcher

PubMed DOI Crossref

Microchip-Based Single-Cell Imaging Reveals That CD56dimCD57-KIR-NKG2A+ NK Cells Have More Dynamic Migration Associated with Increased Target Cell Conjugation and Probability of Killing Compared to CD56dimCD57-KIR-NKG2A- NK Cells.

Forslund E, Sohlberg E, Enqvist M, ..., Malmberg KJ, Önfelt B

J. Immunol. 195 (7) 3374-3381 [2015-10-01; online 2015-08-28]

Affiliated researcher

PubMed DOI Crossref

Homozygous loss-of-function variants in European cosmopolitan and isolate populations.

Kaiser VB, Svinti V, Prendergast JG, ..., Semple CA, Wilson JF

Hum. Mol. Genet. 24 (19) 5464-5474 [2015-10-01; online 2015-07-14]

Affiliated researcher

PubMed DOI Crossref

Transcriptome Profiling Reveals Degree of Variability in Induced Pluripotent Stem Cell Lines: Impact for Human Disease Modeling.

Schuster J, Halvardson J, Pilar Lorenzo L, ..., Feuk L, Dahl N

Cell Reprogram 17 (5) 327-337 [2015-10-00; online 2015-09-08]

Affiliated researcher

PubMed DOI Crossref

The gut microbiota modulates host amino acid and glutathione metabolism in mice

Mardinoglu A, Shoaie S, Bergentall M, ..., Bäckhed F, Nielsen J

Mol Syst Biol 11 (10) 834 [2015-10-00; online 2015-10-16]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

The effects of age and gender on plasma levels of 63 cytokines.

Larsson A, Carlsson L, Gordh T, ..., Thulin M, Kamali-Moghaddam M

J. Immunol. Methods 425 (-) 58-61 [2015-10-00; online 2015-06-14]

Affiliated researcher

PubMed DOI Crossref

The cyanobacterium Mastigocladus fulfills the nitrogen demand of a terrestrial hot spring microbial mat.

Estrella Alcamán M, Fernandez C, Delgado A, Bergman B, Díez B

ISME J 9 (10) 2290-2303 [2015-10-00; online 2015-07-31]

Affiliated researcher

PubMed DOI Crossref

The complex interplay between cell-intrinsic and cell-extrinsic factors driving the evolution of chronic lymphocytic leukemia.

Sutton LA, Rosenquist R

Semin. Cancer Biol. 34 (-) 22-35 [2015-10-00; online 2015-05-09]

Affiliated researcher

PubMed DOI Crossref

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

Winkler TW, Justice AE, Graff M, ..., Kutalik Z, Loos RJ

PLoS Genet 11 (10) e1005378 [2015-10-00; online 2015-10-01]

Affiliated researcher

PubMed DOI Crossref

The Human Gut Microbiome as a Transporter of Antibiotic Resistance Genes between Continents.

Bengtsson-Palme J, Angelin M, Huss M, ..., Larsson DG, Johansson A

Antimicrob. Agents Chemother. 59 (10) 6551-6560 [2015-10-00; online 2015-08-10]

Affiliated researcher DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Targeting protein-protein interactions (PPIs) of transcription factors: Challenges of intrinsically disordered proteins (IDPs) and regions (IDRs).

Sammak S, Zinzalla G

Prog. Biophys. Mol. Biol. 119 (1) 41-46 [2015-10-00; online 2015-06-27]

Affiliated researcher

PubMed DOI Crossref

Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase.

Kleinschmidt TK, Haraldsson M, Basavarajappa D, ..., Lindbom L, Haeggström JZ

J. Pharmacol. Exp. Ther. 355 (1) 108-116 [2015-10-00; online 2015-08-17]

Affiliated researcher

PubMed DOI Crossref

Systematic screening of imaging biomarkers for the Islets of Langerhans, among clinically available positron emission tomography tracers.

Karlsson F, Antonodimitrakis PC, Eriksson O

Nucl. Med. Biol. 42 (10) 762-769 [2015-10-00; online 2015-06-10]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Supraphysiological hormonal status, anxiety disorders, and COMT Val/Val genotype are associated with reduced sensorimotor gating in women.

Comasco E, Hellgren C, Olivier J, Skalkidou A, Sundström Poromaa I

Psychoneuroendocrinology 60 (-) 217-223 [2015-10-00; online 2015-07-02]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Soluble Tumor Necrosis Factor Receptor 1 Is Associated with Glomerular Filtration Rate Progression and Incidence of Chronic Kidney Disease in Two Community-Based Cohorts of Elderly Individuals.

Carlsson AC, Nordquist L, Larsson TE, ..., Lind L, Ärnlöv J

Cardiorenal Med 5 (4) 278-288 [2015-10-00; online 2015-07-31]

Affiliated researcher

PubMed DOI Crossref

Signatures of post-zygotic structural genetic aberrations in the cells of histologically normal breast tissue that can predispose to sporadic breast cancer.

Forsberg LA, Rasi C, Pekar G, ..., Tot T, Dumanski JP

Genome Res. 25 (10) 1521-1535 [2015-10-00; online 2015-10-03]

Affiliated researcher

PubMed DOI Crossref

RNA editing of non-coding RNA and its role in gene regulation.

Daniel C, Lagergren J, Öhman M

Biochimie 117 (-) 22-27 [2015-10-00; online 2015-06-05]

Affiliated researcher

PubMed DOI Crossref

Quantitative Mass Spectrometry Reveals Partial Translational Regulation for Dosage Compensation in Chicken.

Uebbing S, Konzer A, Xu L, ..., Bergquist J, Ellegren H

Mol. Biol. Evol. 32 (10) 2716-2725 [2015-10-00; online 2015-06-24]

Affiliated researcher

PubMed DOI Crossref

Profound parental bias associated with chromosome 14 acquired uniparental disomy indicates targeting of an imprinted locus.

Chase A, Leung W, Tapper W, ..., Dumanski JP, Cross NC

Leukemia 29 (10) 2069-2074 [2015-10-00; online 2015-05-20]

Affiliated researcher

PubMed DOI Crossref

Positive Modulation of the Glycine Receptor by Means of Glycine Receptor-Binding Aptamers.

Shalaly ND, Aneiros E, Blank M, ..., Andersson CV, Sandberg K

J Biomol Screen 20 (9) 1112-1123 [2015-10-00; online 2015-06-12]

Affiliated researcher

PubMed DOI Crossref

Neuroimaging the Menstrual Cycle and Premenstrual Dysphoric Disorder.

Comasco E, Sundström-Poromaa I

Curr Psychiatry Rep 17 (10) 77 [2015-10-00; online 2015-08-15]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Mitogenomic analysis of a 50-generation chicken pedigree reveals a rapid rate of mitochondrial evolution and evidence for paternal mtDNA inheritance.

Alexander M, Ho SY, Molak M, ..., Andersson L, Larson G

Biol. Lett. 11 (10) - [2015-10-00; online 2015-10-30]

Affiliated researcher

PubMed DOI Crossref

Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets in vitro.

Kloster-Jensen K, Vethe NT, Bremer S, ..., Bergan S, Scholz H

Transpl. Int. 28 (10) 1152-1161 [2015-10-00; online 2015-06-23]

Affiliated researcher

PubMed DOI Crossref

Influence of surface modification and static pressure on microdialysis protein extraction efficiency.

Chu J, Undin T, Lind SB, Hjort K, Dahlin AP

Biomed Microdevices 17 (5) 96 [2015-10-00; online 2015-09-08]

Affiliated researcher

PubMed DOI Crossref

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome.

Simonson OE, Mougiakakos D, Heldring N, ..., Grinnemo KH, Le Blanc K

Stem Cells Transl Med 4 (10) 1199-1213 [2015-10-00; online 2015-08-18]

Affiliated researcher

PubMed DOI Crossref

Graft function 1 year after pregnancy in an islet-transplanted patient.

Schive SW, Scholz H, Sahraoui A, ..., Foss A, Jenssen TG

Transpl. Int. 28 (10) 1235-1239 [2015-10-00; online 2015-05-11]

Affiliated researcher

PubMed DOI Crossref

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index.

Yang J, Bakshi A, Zhu Z, ..., Goddard ME, Visscher PM

Nat. Genet. 47 (10) 1114-1120 [2015-10-00; online 2015-08-31]

Affiliated researcher

PubMed DOI Crossref

Flight-induced changes in gene expression in the Glanville fritillary butterfly.

Kvist J, Mattila AL, Somervuo P, ..., Frilander MJ, Hanski I

Mol. Ecol. 24 (19) 4886-4900 [2015-10-00; online 2015-09-04]

Affiliated researcher

PubMed DOI Crossref

Determination of 21-hydroxylase autoantibodies: inter-laboratory concordance in the Euradrenal International Serum Exchange Program.

Falorni A, Bini V, Betterle C, ..., Lernmark Å, Husebye E

Clin. Chem. Lab. Med. 53 (11) 1761-1770 [2015-10-00; online 2015-03-27]

Affiliated researcher

PubMed DOI Crossref

Cis-Regulatory Changes Associated with a Recent Mating System Shift and Floral Adaptation in Capsella.

Steige KA, Reimegård J, Koenig D, Scofield DG, Slotte T

Mol. Biol. Evol. 32 (10) 2501-2514 [2015-10-00; online 2015-08-28]

Affiliated researcher SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

BCG Skin Infection Triggers IL-1R-MyD88-Dependent Migration of EpCAMlow CD11bhigh Skin Dendritic cells to Draining Lymph Node During CD4+ T-Cell Priming.

Bollampalli VP, Harumi Yamashiro L, Feng X, ..., Nylén S, Rothfuchs AG

PLoS Pathog 11 (10) e1005206 [2015-10-00; online 2015-10-06]

Affiliated researcher

PubMed DOI Crossref

Acoustophoretic removal of proteins from blood components.

Tenje M, Lundgren MN, Swärd-Nilsson AM, ..., Lyxe L, Lenshof A

Biomed Microdevices 17 (5) 95 [2015-10-00; online 2015-09-01]

Affiliated researcher

DOI Crossref

Acid-Base Catalyst Discriminates between a Fructose 6-Phosphate Aldolase and a Transaldolase

Stellmacher L, Sandalova T, Leptihn S, ..., Sprenger GA, Samland AK

ChemCatChem 7 (19) 3140-3151 [2015-10-00; online 2015-08-06]

Affiliated researcher

PubMed DOI Crossref

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.

Nikpay M, Goel A, Won HH, ..., Samani NJ, Farrall M

Nat. Genet. 47 (10) 1121-1130 [2015-10-00; online 2015-09-07]

Affiliated researcher

PubMed DOI Crossref

Virtual Screening for Transition State Analogue Inhibitors of IRAP Based on Quantum Mechanically Derived Reaction Coordinates.

Svensson F, Engen K, Lundbäck T, Larhed M, Sköld C

J Chem Inf Model 55 (9) 1984-1993 [2015-09-28; online 2015-08-14]

Affiliated researcher

PubMed DOI Crossref

Serendipitous Meta-Transcriptomics: The Fungal Community of Norway Spruce (Picea abies).

Delhomme N, Sundström G, Zamani N, ..., Grabherr MG, Street NR

PLoS ONE 10 (9) e0139080 [2015-09-28; online 2015-09-28]

Affiliated researcher

PubMed DOI Crossref

Identification of Novel Epigenetic Markers of Prostate Cancer by NotI-Microarray Analysis.

Dmitriev AA, Rosenberg EE, Krasnov GS, ..., Senchenko VN, Kashuba VI

Dis. Markers 2015 (-) 241301 [2015-09-28; online 2015-09-28]

Affiliated researcher

PubMed DOI Crossref

Exploring microbial dark matter to resolve the deep archaeal ancestry of eukaryotes.

Saw JH, Spang A, Zaremba-Niedzwiedzka K, ..., Guy L, Ettema TJ

Philos. Trans. R. Soc. Lond., B, Biol. Sci. 370 (1678) 20140328 [2015-09-26; online 2015-09-02]

Affiliated researcher

PubMed DOI Crossref

Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett's Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium.

Lagergren K, Ek WE, Levine D, ..., Nyren O, Lagergren J

PLoS ONE 10 (9) e0138738 [2015-09-25; online 2015-09-25]

Affiliated researcher

PubMed DOI Crossref

Neuropeptide S- and Neuropeptide S receptor-expressing neuron populations in the human pons.

Adori C, Barde S, Bogdanovic N, ..., Kovacs GG, Hökfelt T

Front Neuroanat 9 (-) 126 [2015-09-25; online 2015-09-25]

Affiliated researcher

PubMed DOI Crossref

Molecular architecture of the active mitochondrial protein gate.

Shiota T, Imai K, Qiu J, ..., Lithgow T, Endo T

Science 349 (6255) 1544-1548 [2015-09-25; online 2015-09-26]

Affiliated researcher

PubMed DOI Crossref

Highly specific DNA detection employing ligation on suspension bead array readout.

Mezger A, Kühnemund M, Nilsson M, Herthnek D

N Biotechnol 32 (5) 504-510 [2015-09-25; online 2015-02-11]

Affiliated researcher

PubMed DOI Crossref

Development of Immunoassays for the Quantitative Assessment of Amyloid-β in the Presence of Therapeutic Antibody: Application to Pre-Clinical Studies.

Bogstedt A, Groves M, Tan K, ..., McFarlane M, Höglund K

J. Alzheimers Dis. 46 (4) 1091-1101 [2015-09-25; online 2015-09-25]

Affiliated researcher

PubMed DOI Crossref

Canine CNGA3 Gene Mutations Provide Novel Insights into Human Achromatopsia-Associated Channelopathies and Treatment

Tanaka N, Dutrow EV, Miyadera K, ..., Tanaka JC, Guziewicz KE

PLoS ONE 10 (9) e0138943 [2015-09-25; online 2015-09-25]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Genome-wide maps of nuclear lamina interactions in single human cells.

Kind J, Pagie L, de Vries SS, ..., van Oudenaarden A, van Steensel B

Cell 163 (1) 134-147 [2015-09-24; online 2015-09-10]

Affiliated researcher Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Ancient genomes link early farmers from Atapuerca in Spain to modern-day Basques.

Günther T, Valdiosera C, Malmström H, ..., Götherström A, Jakobsson M

Proc. Natl. Acad. Sci. U.S.A. 112 (38) 11917-11922 [2015-09-22; online 2015-09-08]

Affiliated researcher

PubMed DOI Crossref

Gene expression profiling of pre-eclamptic placentae by RNA sequencing.

Kaartokallio T, Cervera A, Kyllönen A, ..., Laivuori H, FINNPEC Core Investigator Group

Sci Rep 5 (-) 14107 [2015-09-21; online 2015-09-21]

Affiliated researcher

PubMed DOI Crossref

Enhanced Protein Production in Escherichia coli by Optimization of Cloning Scars at the Vector-Coding Sequence Junction.

Mirzadeh K, Martínez V, Toddo S, ..., Nørholm MH, Daley DO

ACS Synth. Biol. 4 (9) 959-965 [2015-09-18; online 2015-05-15]

Affiliated researcher

PubMed DOI Crossref

PARP1- and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription.

Zhao H, Sifakis EG, Sumida N, ..., Imreh MP, Göndör A

Mol. Cell 59 (6) 984-997 [2015-09-17; online 2015-08-27]

Affiliated researcher

PubMed DOI Crossref

Genetic and morphological evidence for introgression between three species of willows.

Fogelqvist J, Verkhozina AV, Katyshev AI, ..., Lascoux M, Berlin S

BMC Evol Biol BMC Evolutionary Biology 15 (-) 193 [2015-09-16; online 2015-09-16]

Affiliated researcher

PubMed DOI Crossref

WNT3 involvement in human bladder exstrophy and cloaca development in zebrafish.

Baranowska Körberg I, Hofmeister W, Markljung E, ..., Lindstrand A, Nordenskjöld A

Hum. Mol. Genet. 24 (18) 5069-5078 [2015-09-15; online 2015-06-23]

Affiliated researcher

PubMed DOI Crossref

Modeling the mechanisms of biological GTP hydrolysis.

Carvalho AT, Szeler K, Vavitsas K, Åqvist J, Kamerlin SC

Arch. Biochem. Biophys. 582 (-) 80-90 [2015-09-15; online 2015-02-27]

Affiliated researcher

PubMed DOI Crossref

HLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma.

Thuring C, Follin E, Geironson L, ..., Buus S, Paulsson KM

Br. J. Cancer 113 (6) 952-962 [2015-09-15; online 2015-08-27]

Affiliated researcher

PubMed DOI Crossref

Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells.

Roy A, Coum A, Marinescu VD, ..., Pontén F, Tchougounova E

Oncotarget 6 (27) 23647-23661 [2015-09-15; online 2015-07-15]

Affiliated researcher

PubMed DOI Crossref

Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing.

Parry M, Rose-Zerilli MJ, Ljungström V, ..., Oscier D, Strefford JC

Clin. Cancer Res. 21 (18) 4174-4183 [2015-09-15; online 2015-03-16]

Affiliated researcher

PubMed DOI Crossref

Comparative genomic analyses of freshly isolated Giardia intestinalis assemblage A isolates.

Ankarklev J, Franzén O, Peirasmaki D, ..., Andersson B, Svärd SG

BMC Genomics 16 (-) 697 [2015-09-15; online 2015-09-15]

Affiliated researcher

PubMed DOI Crossref

E-cadherin can limit the transforming properties of activating β-catenin mutations.

Huels DJ, Ridgway RA, Radulescu S, ..., Clarke AR, Sansom OJ

EMBO J. 34 (18) 2321-2333 [2015-09-14; online 2015-08-03]

Affiliated researcher

PubMed DOI Crossref

Determination of obesity associated gene variants related to TMEM18 through ultra-deep targeted re-sequencing in a case-control cohort for pediatric obesity.

Rask-Andersen M, Sällman Almén M, Jacobsson JA, ..., Fredriksson R, Schiöth HB

Genet Res (Camb) 97 (-) e16 [2015-09-14; online 2015-09-14]

Affiliated researcher

PubMed DOI Crossref

Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development.

Töhönen V, Katayama S, Vesterlund L, ..., Hovatta O, Kere J

Nat Commun 6 (-) 8207 [2015-09-11; online 2015-09-11]

Affiliated researcher

PubMed DOI Crossref

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF.

Huffman JE, de Vries PS, Morrison AC, ..., O'Donnell CJ, Smith NL

Blood 126 (11) e19-e29 [2015-09-10; online 2015-06-23]

Affiliated researcher

PubMed DOI Crossref

STED-FLCS: An Advanced Tool to Reveal Spatiotemporal Heterogeneity of Molecular Membrane Dynamics.

Vicidomini G, Ta H, Honigmann A, ..., Hell SW, Eggeling C

Nano Lett. 15 (9) 5912-5918 [2015-09-09; online 2015-08-07]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women.

Arner P, Sinha I, Thorell A, ..., Dahlman-Wright K, Dahlman I

Clin Epigenetics 7 (-) 93 [2015-09-08; online 2015-09-08]

Affiliated researcher

PubMed DOI Crossref

Cotranslational Protein Folding inside the Ribosome Exit Tunnel.

Nilsson OB, Hedman R, Marino J, ..., Beckmann R, von Heijne G

Cell Reports 12 (10) 1533-1540 [2015-09-08; online 2015-08-28]

Affiliated researcher

PubMed DOI Crossref

Roles of miR-196a on gene regulation of neuroendocrine tumor cells.

Li SC, Shi H, Khan M, ..., Öberg K, Giandomenico V

Mol. Cell. Endocrinol. 412 (-) 131-139 [2015-09-05; online 2015-06-04]

Affiliated researcher

PubMed DOI Crossref

Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project.

Horvatovich P, Lundberg EK, Chen YJ, ..., Paik YK, Hancock WS

J. Proteome Res. 14 (9) 3415-3431 [2015-09-04; online 2015-07-23]

Affiliated researcher

PubMed DOI Crossref

Metrics for the Human Proteome Project 2015: Progress on the Human Proteome and Guidelines for High-Confidence Protein Identification.

Omenn GS, Lane L, Lundberg EK, ..., Nesvizhskii AI, Deutsch EW

J. Proteome Res. 14 (9) 3452-3460 [2015-09-04; online 2015-07-30]

Affiliated researcher

PubMed DOI Crossref

SUV3 helicase is required for correct processing of mitochondrial transcripts.

Clemente P, Pajak A, Laine I, ..., Freyer C, Wredenberg A

Nucleic Acids Res. 43 (15) 7398-7413 [2015-09-03; online 2015-07-07]

Affiliated researcher

PubMed DOI Crossref

Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures.

Stödberg T, McTague A, Ruiz AJ, ..., Wedell A, Kurian MA

Nat Commun 6 (-) 8038 [2015-09-03; online 2015-09-03]

Affiliated researcher

PubMed DOI Crossref

Efficient exploration of pan-cancer networks by generalized covariance selection and interactive web content.

Kling T, Johansson P, Sanchez J, ..., Jörnsten R, Nelander S

Nucleic Acids Res. 43 (15) e98 [2015-09-03; online 2015-05-07]

Affiliated researcher

PubMed DOI Crossref

Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis.

Rydén M, Uzunel M, Hård JL, ..., Mattsson J, Arner P

Cell Metab. 22 (3) 408-417 [2015-09-01; online 2015-07-16]

Affiliated researcher

PubMed DOI Crossref

A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development.

Specks J, Lecona E, Lopez-Contreras AJ, Fernandez-Capetillo O

Mol. Cell. Biol. 35 (17) 2910-2917 [2015-09-01; online 2015-06-15]

Affiliated researcher

PubMed DOI Crossref

miR-200a inhibits migration of triple-negative breast cancer cells through direct repression of the EPHA2 oncogene.

Tsouko E, Wang J, Frigo DE, Aydoğdu E, Williams C

Carcinogenesis 36 (9) 1051-1060 [2015-09-00; online 2015-06-18]

Affiliated researcher

PubMed DOI Crossref

[11C]Carfentanil Binds Preferentially to μ-Opioid Receptor Subtype 1 Compared to Subtype 2

Eriksson O, Antoni G

Mol Imaging 14 (9) 7290.2015.00019 [2015-09-00; online 2015-09-00]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Whole exome sequencing identifies LRP1 as a pathogenic gene in autosomal recessive keratosis pilaris atrophicans.

Klar J, Schuster J, Khan TN, ..., Baig SM, Dahl N

J. Med. Genet. 52 (9) 599-606 [2015-09-00; online 2015-07-03]

Affiliated researcher

PubMed DOI Crossref

Use of a proximity extension assay proteomics chip to discover new biomarkers for human atherosclerosis.

Lind L, Ärnlöv J, Lindahl B, ..., Sundström J, Ingelsson E

Atherosclerosis 242 (1) 205-210 [2015-09-00; online 2015-07-14]

Affiliated researcher

PubMed DOI Crossref

Transcriptomics of colour patterning and coloration shifts in crows.

Poelstra JW, Vijay N, Hoeppner MP, Wolf JB

Mol. Ecol. 24 (18) 4617-4628 [2015-09-00; online 2015-09-10]

Affiliated researcher

DOI Crossref

Towards a stereoselective synthesis of α,α-disubstituted proline analogues

Das SK, Bhatt N, Mujahid M, ..., Naicker T, Govender T

Tetrahedron Letters 56 (37) 5172-5174 [2015-09-00; online 2015-09-00]

Affiliated researcher

PubMed DOI Crossref

The clinical impact of IKZF1 deletions in paediatric B-cell precursor acute lymphoblastic leukaemia is independent of minimal residual disease stratification in Nordic Society for Paediatric Haematology and Oncology treatment protocols used between 1992 and 2013.

Olsson L, Ivanov Öfverholm I, Norén-Nyström U, ..., Barbany G, Johansson B

Br. J. Haematol. 170 (6) 847-858 [2015-09-00; online 2015-05-27]

Affiliated researcher

PubMed DOI Crossref

Systemic Lupus Erythematosus--A Disease with A Dysregulated Type I Interferon System.

Hagberg N, Rönnblom L

Scand. J. Immunol. 82 (3) 199-207 [2015-09-00; online 2015-06-24]

Affiliated researcher

DOI Crossref

Synthesis of enantiopure angiotensin II type 2 receptor [AT2R] antagonist EMA401

Wakchaure PB, Bremberg U, Wannberg J, Larhed M

Tetrahedron 71 (38) 6881-6887 [2015-09-00; online 2015-09-00]

Affiliated researcher

PubMed DOI Crossref

Species Tree Inference Using a Mixture Model.

Ullah I, Parviainen P, Lagergren J

Mol. Biol. Evol. 32 (9) 2469-2482 [2015-09-00; online 2015-05-11]

Affiliated researcher

PubMed DOI Crossref

Perfluoroalkyl substances (PFAS) including structural PFOS isomers in plasma from elderly men and women from Sweden: Results from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS).

Salihovic S, Kärrman A, Lind L, ..., Lindström G, van Bavel B

Environ Int 82 (-) 21-27 [2015-09-00; online 2015-05-22]

Affiliated researcher

PubMed DOI Crossref

Peptide-Centric Proteome Analysis: An Alternative Strategy for the Analysis of Tandem Mass Spectrometry Data.

Ting YS, Egertson JD, Payne SH, ..., Noble WS, MacCoss MJ

Mol. Cell Proteomics 14 (9) 2301-2307 [2015-09-00; online 2015-07-27]

Affiliated researcher

PubMed DOI Crossref

Newtonian cell interactions shape natural killer cell education.

Goodridge JP, Önfelt B, Malmberg KJ

Immunol. Rev. 267 (1) 197-213 [2015-09-00; online 2015-08-19]

Affiliated researcher

DOI Crossref

Mechanisms of carbon fixation and engineering for increased carbon fixation in cyanobacteria

Durall C, Lindblad P

Algal Research 11 (-) 263-270 [2015-09-00; online 2015-09-00]

Affiliated researcher

PubMed DOI Crossref

Finnsson J, Sundblom J, Dahl N, Melberg A, Raininko R

Ann. Neurol. 78 (3) 412-425 [2015-09-00; online 2015-07-27]

Affiliated researcher

PubMed DOI Crossref

Involvement of CD9 and PDGFR in migration is evolutionarily conserved from Drosophila glia to human glioma.

Jeibmann A, Halama K, Witte HT, ..., Klämbt C, Paulus W

J. Neurooncol. 124 (3) 373-383 [2015-09-00; online 2015-07-30]

Affiliated researcher

PubMed DOI Crossref

IPeak: An open source tool to combine results from multiple MS/MS search engines.

Wen B, Du C, Li G, ..., Xu X, Wang J

Proteomics 15 (17) 2916-2920 [2015-09-00; online 2015-08-06]

Affiliated researcher

PubMed DOI Crossref

Gut microbiome and innate immune response patterns in IgE-associated eczema.

West CE, Rydén P, Lundin D, ..., Tulic MK, Prescott SL

Clin. Exp. Allergy 45 (9) 1419-1429 [2015-09-00; online 2015-05-07]

Affiliated researcher

PubMed DOI Crossref

Exome sequencing followed by genotyping suggests SYPL2 as a susceptibility gene for morbid obesity.

Jiao H, Arner P, Gerdhem P, ..., Kere J, Dahlman I

Eur. J. Hum. Genet. 23 (9) 1216-1222 [2015-09-00; online 2014-11-19]

Affiliated researcher

PubMed DOI Crossref

Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests.

Frånberg M, Gertow K, Hamsten A, ..., Lagergren J, Sennblad B

PLoS Genet 11 (9) e1005502 [2015-09-00; online 2015-09-24]

Affiliated researcher

PubMed DOI Crossref

Computer-aided diagnosis system based on fuzzy logic for breast cancer categorization.

Miranda GH, Felipe JC

Comput Biol Med 64 (-) 334-346 [2015-09-00; online 2014-10-14]

Gisele Miranda SciLifeLab Fellow

PubMed DOI Crossref

Clumpak: a program for identifying clustering modes and packaging population structure inferences across K.

Kopelman NM, Mayzel J, Jakobsson M, Rosenberg NA, Mayrose I

Mol Ecol Resour 15 (5) 1179-1191 [2015-09-00; online 2015-02-27]

Affiliated researcher

PubMed DOI Crossref

Chlorophyll f-driven photosynthesis in a cavernous cyanobacterium.

Behrendt L, Brejnrod A, Schliep M, ..., Larkum AW, Kühl M

ISME J 9 (9) 2108-2111 [2015-09-00; online 2015-02-10]

Lars Behrendt SciLifeLab Fellow

PubMed DOI Crossref

Auxotrophy and intrapopulation complementary in the 'interactome' of a cultivated freshwater model community.

Garcia SL, Buck M, McMahon KD, ..., Eiler A, Warnecke F

Mol. Ecol. 24 (17) 4449-4459 [2015-09-00; online 2015-08-08]

Affiliated researcher Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

Analysis of the genetic architecture of susceptibility to cervical cancer indicates that common SNPs explain a large proportion of the heritability.

Chen D, Cui T, Ek WE, ..., Wang H, Gyllensten U

Carcinogenesis 36 (9) 992-998 [2015-09-00; online 2015-06-04]

Affiliated researcher

PubMed DOI Crossref

Addiction to MTH1 protein results in intense expression in human breast cancer tissue as measured by liquid chromatography-isotope-dilution tandem mass spectrometry.

Coskun E, Jaruga P, Jemth AS, ..., Helleday T, Dizdaroglu M

DNA Repair (Amst.) 33 (-) 101-110 [2015-09-00; online 2015-06-23]

Affiliated researcher

PubMed DOI Crossref

Prenatal and Postpartum Evening Salivary Cortisol Levels in Association with Peripartum Depressive Symptoms.

Iliadis SI, Comasco E, Sylvén S, ..., Sundström Poromaa I, Skalkidou A

PLoS ONE 10 (8) e0135471 [2015-08-31; online 2015-08-31]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.

Kharaziha P, Chioureas D, Rutishauser D, ..., Nilsson S, Panaretakis T

Oncotarget 6 (25) 21740-21754 [2015-08-28; online 2015-04-07]

Affiliated researcher

PubMed DOI Crossref

The Nucleus-Localized Epidermal Growth Factor Receptor Is SUMOylated.

Packham S, Lin Y, Zhao Z, ..., Rutishauser D, Larsson O

Biochemistry 54 (33) 5157-5166 [2015-08-25; online 2015-08-14]

Affiliated researcher

PubMed DOI Crossref

Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast.

Huang M, Bai Y, Sjostrom SL, ..., Andersson-Svahn H, Nielsen J

Proc. Natl. Acad. Sci. U.S.A. 112 (34) E4689-E4696 [2015-08-25; online 2015-08-10]

Affiliated researcher

PubMed DOI Crossref

POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans.

Raghavan M, Steinrücken M, Harris K, ..., Nielsen R, Willerslev E

Science 349 (6250) aab3884 [2015-08-21; online 2015-07-21]

Affiliated researcher

PubMed DOI Crossref

Increased resistance to proteasome inhibitors in multiple myeloma mediated by cIAP2--implications for a combinatorial treatment.

Fristedt Duvefelt C, Lub S, Agarwal P, ..., Vanderkerken K, Jernberg Wiklund H

Oncotarget 6 (24) 20621-20635 [2015-08-21; online 2015-06-04]

Affiliated researcher

PubMed DOI Crossref

Harmful somatic amino acid substitutions affect key pathways in cancers.

Niroula A, Vihinen M

BMC Med Genomics 8 (-) 53 [2015-08-19; online 2015-08-19]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Experiences with workflows for automating data-intensive bioinformatics.

Spjuth O, Bongcam-Rudloff E, Hernández GC, ..., Siretskiy A, Vassilev D

Biol. Direct 10 (-) 43 [2015-08-19; online 2015-08-19]

Affiliated researcher

PubMed DOI Crossref

Conformational gating dynamics in the GluCl anion-selective chloride channel.

Yoluk Ö, Lindahl E, Andersson M

ACS Chem Neurosci 6 (8) 1459-1467 [2015-08-19; online 2015-06-02]

Affiliated researcher

PubMed DOI Crossref

Factors mediating plastid dependency and the origins of parasitism in apicomplexans and their close relatives

Janouškovec J, Tikhonenkov DV, Burki F, ..., Mylnikov AP, Keeling PJ

Proceedings of the National Academy of Sciences 112 (33) 10200-10207 [2015-08-18; online 2015-02-25]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium.

Yu NY, Hallström BM, Fagerberg L, ..., Uhlén M, Daub CO

Nucleic Acids Res. 43 (14) 6787-6798 [2015-08-18; online 2015-06-27]

Affiliated researcher

PubMed DOI Crossref

Genome-wide association study of toxic metals and trace elements reveals novel associations.

Ng E, Lind PM, Lindgren C, ..., Morris A, Lind L

Hum. Mol. Genet. 24 (16) 4739-4745 [2015-08-15; online 2015-05-29]

Affiliated researcher

PubMed DOI Crossref

Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry.

Nettleton JA, Follis JL, Ngwa JS, ..., Loos RJ, Franks PW

Hum. Mol. Genet. 24 (16) 4728-4738 [2015-08-15; online 2015-05-20]

Affiliated researcher

PubMed DOI Crossref

miR-184 Regulates Pancreatic β-Cell Function According to Glucose Metabolism.

Tattikota SG, Rathjen T, Hausser J, ..., Friedländer MR, Poy MN

J Biol Chem 290 (33) 20284-20294 [2015-08-14; online 2015-07-07]

Affiliated researcher Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.

Persson J, Strawbridge RJ, McLeod O, ..., Hamsten A, IMPROVE Study Group

J Am Heart Assoc 4 (8) e001853 [2015-08-14; online 2015-08-14]

Affiliated researcher

PubMed DOI Crossref

Genome-wide association study of warfarin maintenance dose in a Brazilian sample.

Parra EJ, Botton MR, Perini JA, ..., Hutz MH, Suarez-Kurtz G

Pharmacogenomics 16 (11) 1253-1263 [2015-08-12; online 2015-08-12]

Affiliated researcher

PubMed DOI Crossref

A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12.

Bianchi M, Dahlgren S, Massey J, ..., Lingaas F, Rosengren Pielberg G

PLoS ONE 10 (8) e0134720 [2015-08-11; online 2015-08-11]

Affiliated researcher

PubMed DOI Crossref

Adaptive mutations in sugar metabolism restore growth on glucose in a pyruvate decarboxylase negative yeast strain.

Zhang Y, Liu G, Engqvist MK, ..., Siewers V, Nielsen J

Microb Cell Fact 14 (-) 116 [2015-08-08; online 2015-08-08]

Affiliated researcher

PubMed DOI Crossref

Nanopore arrays in a silicon membrane for parallel single-molecule detection: DNA translocation.

Zhang M, Schmidt T, Jemt A, ..., Lundeberg J, Linnros J

Nanotechnology 26 (31) 314002 [2015-08-07; online 2015-07-16]

Affiliated researcher

PubMed DOI Crossref

Comparative Proteomic Analysis of Human Liver Tissue and Isolated Hepatocytes with a Focus on Proteins Determining Drug Exposure.

Vildhede A, Wiśniewski JR, Norén A, Karlgren M, Artursson P

J. Proteome Res. 14 (8) 3305-3314 [2015-08-07; online 2015-07-20]

Affiliated researcher

PubMed DOI Crossref

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome.

Shoaie S, Ghaffari P, Kovatcheva-Datchary P, ..., Bäckhed F, Nielsen J

Cell Metab. 22 (2) 320-331 [2015-08-04; online 2015-08-06]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2.

Carter M, Jemth AS, Hagenkort A, ..., Helleday T, Stenmark P

Nat Commun 6 (-) 7871 [2015-08-04; online 2015-08-04]

Affiliated researcher

PubMed DOI Crossref

Improved canine exome designs, featuring ncRNAs and increased coverage of protein coding genes.

Broeckx BJ, Hitte C, Coopman F, ..., Van Nieuwerburgh F, Deforce D

Sci Rep 5 (-) 12810 [2015-08-03; online 2015-08-03]

Affiliated researcher

PubMed DOI Crossref

Identifying and Assessing Interesting Subgroups in a Heterogeneous Population.

Lee W, Alexeyenko A, Pernemalm M, ..., Lehtiö J, Pawitan Y

Biomed Res Int 2015 (-) 462549 [2015-08-03; online 2015-08-03]

Affiliated researcher

PubMed DOI Crossref

Heat differentiated complement factor profiling.

Hamsten C, Skattum L, Truedsson L, ..., Nilsson P, Neiman M

J Proteomics 126 (-) 155-162 [2015-08-03; online 2015-06-03]

Affiliated researcher

PubMed DOI Crossref

Genome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution.

Sahlén P, Abdullayev I, Ramsköld D, ..., Lundeberg J, Sandberg R

Genome Biol. 16 (-) 156 [2015-08-03; online 2015-08-03]

Affiliated researcher

PubMed DOI Crossref

Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer.

O'Hurley G, Busch C, Fagerberg L, ..., Uhlén M, Pontén F

PLoS ONE 10 (8) e0133449 [2015-08-03; online 2015-08-03]

Affiliated researcher

PubMed DOI Crossref

Secretome protein signature of human gastrointestinal stromal tumor cells.

Berglund E, Daré E, Branca RM, ..., Kim J, Bränström R

Exp. Cell Res. 336 (1) 158-170 [2015-08-01; online 2015-05-14]

Affiliated researcher

PubMed DOI Crossref

Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci.

Demerath EW, Guan W, Grove ML, ..., Pankow JS, Boerwinkle E

Hum. Mol. Genet. 24 (15) 4464-4479 [2015-08-01; online 2015-05-01]

Affiliated researcher

PubMed DOI Crossref

Effect of genetic variations on ticagrelor plasma levels and clinical outcomes.

Varenhorst C, Eriksson N, Johansson Å, ..., Wallentin L, PLATO Investigators

Eur. Heart J. 36 (29) 1901-1912 [2015-08-01; online 2015-05-02]

Affiliated researcher

PubMed DOI Crossref

p73 is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF and TGFβ signaling.

Fernandez-Alonso R, Martin-Lopez M, Gonzalez-Cano L, ..., Marques MM, Marin MC

Cell Death Differ. 22 (8) 1287-1299 [2015-08-00; online 2015-01-09]

Affiliated researcher

PubMed DOI Crossref

Vaccines targeting self-antigens: mechanisms and efficacy-determining parameters.

Saupe F, Huijbers EJ, Hein T, ..., Olsson AK, Hellman L

FASEB J. 29 (8) 3253-3262 [2015-08-00; online 2015-04-13]

Affiliated researcher

PubMed DOI Crossref

Treatment with serotonin reuptake inhibitors during pregnancy is associated with elevated corticotropin-releasing hormone levels.

Hannerfors AK, Hellgren C, Schijven D, ..., Olivier JD, Sundström-Poromaa I

Psychoneuroendocrinology 58 (-) 104-113 [2015-08-00; online 2015-04-21]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Three-dimensional virtual histology of Silurian osteostracan scales revealed by synchrotron radiation microtomography.

Qu Q, Blom H, Sanchez S, Ahlberg P

J. Morphol. 276 (8) 873-888 [2015-08-00; online 2015-03-21]

Affiliated researcher

PubMed DOI Crossref

Polymorphisms in the ABCB1 gene and effect on outcome and toxicity in childhood acute lymphoblastic leukemia.

Gregers J, Gréen H, Christensen IJ, ..., Schmiegelow K, Peterson C

Pharmacogenomics J. 15 (4) 372-379 [2015-08-00; online 2015-01-13]

Affiliated researcher

PubMed DOI Crossref

New paradigms for metabolic modeling of human cells.

Mardinoglu A, Nielsen J

Curr. Opin. Biotechnol. 34 (-) 91-97 [2015-08-00; online 2015-01-02]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory

Cournia Z, Allen TW, Andricioaei I, ..., Smith JC, Bondar AN

J Membrane Biol 248 (4) 611-640 [2015-08-00; online 2015-06-11]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Inflammasomes of the intestinal epithelium

Sellin ME, Maslowski KM, Maloy KJ, Hardt WD

Trends in Immunology 36 (8) 442-450 [2015-08-00; online 2015-08-00]

Mikael Sellin SciLifeLab Fellow

DOI Crossref

Identification ofMoringa oleiferaprotein responsible for the decolorization and pesticide removal from drinking water and industrial effluent - anin silicoandin situevaluation

Pavankumar AR, Singh L

J. Chem. Technol. Biotechnol. 90 (8) 1521-1526 [2015-08-00; online 2014-07-22]

Affiliated researcher

PubMed DOI Crossref

Global miRNA expression and correlation with mRNA levels in primary human bone cells.

Laxman N, Rubin CJ, Mallmin H, ..., Grundberg E, Kindmark A

RNA 21 (8) 1433-1443 [2015-08-00; online 2015-06-15]

Affiliated researcher

PubMed DOI Crossref

Genetic epidemiology, prevalence, and genotype-phenotype correlations in the Swedish population with osteogenesis imperfecta.

Lindahl K, Åström E, Rubin CJ, ..., Ljunggren Ö, Kindmark A

Eur. J. Hum. Genet. 23 (8) 1042-1050 [2015-08-00; online 2015-05-06]

Affiliated researcher

PubMed DOI Crossref

Estrogen receptor alpha and beta in health and disease.

Jia M, Dahlman-Wright K, Gustafsson JÅ

Best Pract. Res. Clin. Endocrinol. Metab. 29 (4) 557-568 [2015-08-00; online 2015-04-26]

Affiliated researcher

PubMed DOI Crossref

Clade- and species-specific features of genome evolution in the Saccharomycetaceae.

Wolfe KH, Armisén D, Proux-Wera E, ..., Gordon JL, Byrne KP

FEMS Yeast Res. 15 (5) fov035 [2015-08-00; online 2015-06-10]

Affiliated researcher

PubMed DOI Crossref

Candidate genes underlying heritable differences in reproductive seasonality between wild and domestic rabbits.

Carneiro M, Piorno V, Rubin CJ, ..., Alves PC, Andersson L

Anim. Genet. 46 (4) 418-425 [2015-08-00; online 2015-05-22]

Affiliated researcher

PubMed DOI Crossref

CAR T-Cell Therapy: The Role of Physical Barriers and Immunosuppression in Lymphoma.

Enblad G, Karlsson H, Loskog AS

Hum. Gene Ther. 26 (8) 498-505 [2015-08-00; online 2015-08-01]

Affiliated researcher

PubMed DOI Crossref

Bisphosphonate-functionalized hyaluronic acid showing selective affinity for osteoclasts as a potential treatment for osteoporosis.

Kootala S, Ossipov D, van den Beucken JJ, Leeuwenburgh S, Hilborn J

Biomater Sci 3 (8) 1197-1207 [2015-08-00; online 2015-06-24]

Affiliated researcher

PubMed DOI Crossref

5 year mortality predictors in 498 103 UK Biobank participants: a prospective population-based study

Ganna A, Ingelsson E

The Lancet 386 (9993) 533-540 [2015-08-00; online 2015-08-00]

Affiliated researcher

PubMed DOI Crossref

HaploPOP: a software that improves population assignment by combining markers into haplotypes.

Duforet-Frebourg N, Gattepaille LM, Blum MG, Jakobsson M

BMC Bioinformatics 16 (-) 242 [2015-07-31; online 2015-07-31]

Affiliated researcher

PubMed DOI Crossref

The novel NADPH oxidase 4 inhibitor GLX351322 counteracts glucose intolerance in high-fat diet-treated C57BL/6 mice.

Anvari E, Wikström P, Walum E, Welsh N

Free Radic. Res. 49 (11) 1308-1318 [2015-07-30; online 2015-07-30]

Affiliated researcher

PubMed DOI Crossref

OCDB: a database collecting genes, miRNAs and drugs for obsessive-compulsive disorder.

Privitera AP, Distefano R, Wefer HA, ..., Pulvirenti A, Giugno R

Database (Oxford) 2015 (-) bav069 [2015-07-30; online 2015-07-30]

Affiliated researcher

PubMed DOI Crossref

Genome-Wide Analyses Suggest Mechanisms Involving Early B-Cell Development in Canine IgA Deficiency.

Olsson M, Tengvall K, Frankowiack M, ..., Hammarström L, Lindblad-Toh K

PLoS ONE 10 (7) e0133844 [2015-07-30; online 2015-07-30]

Affiliated researcher

PubMed DOI Crossref

Global SUMOylation on active chromatin is an acute heat stress response restricting transcription.

Niskanen EA, Malinen M, Sutinen P, ..., Sistonen L, Palvimo JJ

Genome Biol. 16 (1) 153 [2015-07-28; online 2015-07-28]

Anniina Vihervaara SciLifeLab Fellow

PubMed DOI Crossref

Production, Purification, and Characterization of ¹⁵N-Labeled DNA Repair Proteins as Internal Standards for Mass Spectrometric Measurements.

Reddy PT, Jaruga P, Nelson BC, ..., Helleday T, Dizdaroglu M

Meth. Enzymol. 566 (-) 305-332 [2015-07-26; online 2015-07-26]

Affiliated researcher

PubMed DOI Crossref

MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA-DNA triplex structures.

Mondal T, Subhash S, Vaid R, ..., Gorab E, Kanduri C

Nat Commun 6 (-) 7743 [2015-07-24; online 2015-07-24]

Affiliated researcher

PubMed DOI Crossref

Directional dominance on stature and cognition in diverse human populations.

Joshi PK, Esko T, Mattsson H, ..., Polašek O, Wilson JF

Nature 523 (7561) 459-462 [2015-07-23; online 2015-07-01]

Affiliated researcher

PubMed DOI Crossref

DNA rendering of polyhedral meshes at the nanoscale.

Benson E, Mohammed A, Gardell J, ..., Orponen P, Högberg B

Nature 523 (7561) 441-444 [2015-07-23; online 2015-07-24]

Erik Benson SciLifeLab Fellow

PubMed DOI Crossref

Compaction of rolling circle amplification products increases signal integrity and signal-to-noise ratio.

Clausson CM, Arngården L, Ishaq O, ..., Wählby C, Söderberg O

Sci Rep 5 (-) 12317 [2015-07-23; online 2015-07-23]

Affiliated researcher

PubMed DOI Crossref

G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy.

Lyu C, Mulder J, Barde S, ..., Fried K, Shi TJ

Mol Pain 11 (-) 44 [2015-07-22; online 2015-07-22]

Affiliated researcher

PubMed DOI Crossref

Cooperative Electrostatic Interactions Drive Functional Evolution in the Alkaline Phosphatase Superfamily.

Barrozo A, Duarte F, Bauer P, Carvalho AT, Kamerlin SC

J. Am. Chem. Soc. 137 (28) 9061-9076 [2015-07-22; online 2015-07-10]

Affiliated researcher

PubMed DOI Crossref

lobChIP: from cells to sequencing ready ChIP libraries in a single day.

Wallerman O, Nord H, Bysani M, Borghini L, Wadelius C

Epigenetics Chromatin 8 (-) 25 [2015-07-21; online 2015-07-21]

Affiliated researcher

PubMed DOI Crossref

CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface.

Yakymovych I, Yakymovych M, Zang G, ..., Landström M, Heldin CH

J. Cell Biol. 210 (2) 319-332 [2015-07-20; online 2015-07-13]

Affiliated researcher

PubMed DOI Crossref

Mitochondrial ribosome assembly in health and disease

De Silva D, Tu YT, Amunts A, Fontanesi F, Barrientos A

Cell Cycle 14 (14) 2226-2250 [2015-07-18; online 2015-06-00]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Epigenome data release: a participant-centered approach to privacy protection.

Dyke SO, Cheung WA, Joly Y, ..., Walter J, Pastinen T

Genome Biol. 16 (-) 142 [2015-07-17; online 2015-07-17]

Affiliated researcher

PubMed DOI Crossref

Promoter-level expression clustering identifies time development of transcriptional regulatory cascades initiated by ErbB receptors in breast cancer cells.

Mina M, Magi S, Jurman G, ..., Okada-Hatakeyama M, Furlanello C

Sci Rep 5 (-) 11999 [2015-07-16; online 2015-07-16]

Affiliated researcher

PubMed DOI Crossref

Logical transformation of genome-scale metabolic models for gene level applications and analysis.

Zhang C, Ji B, Mardinoglu A, Nielsen J, Hua Q

Bioinformatics 31 (14) 2324-2331 [2015-07-15; online 2015-03-02]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

SAXS-Guided Metadynamics.

Kimanius D, Pettersson I, Schluckebier G, Lindahl E, Andersson M

J Chem Theory Comput 11 (7) 3491-3498 [2015-07-14; online 2015-11-18]

Affiliated researcher

PubMed DOI Crossref

Properties of Organic Liquids when Simulated with Long-Range Lennard-Jones Interactions.

Fischer NM, van Maaren PJ, Ditz JC, Yildirim A, van der Spoel D

J Chem Theory Comput 11 (7) 2938-2944 [2015-07-14; online 2015-06-02]

Affiliated researcher

PubMed DOI Crossref

Incidence of Diabetes Mellitus in Insured Swedish Cats in Relation to Age, Breed and Sex.

Öhlund M, Fall T, Ström Holst B, ..., Bonnett B, Egenvall A

J. Vet. Intern. Med. 29 (5) 1342-1347 [2015-07-14; online 2015-07-14]

Affiliated researcher

PubMed DOI Crossref

Differential Expression Analysis by RNA-Seq Reveals Perturbations in the Platelet mRNA Transcriptome Triggered by Pathogen Reduction Systems.

Osman A, Hitzler WE, Ameur A, Provost P

PLoS ONE 10 (7) e0133070 [2015-07-14; online 2015-07-14]

Affiliated researcher

PubMed DOI Crossref

Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat.

Babbitt PC, Bagos PG, Bairoch A, ..., Vastermark A, Vriend G

Database (Oxford) 2015 (-) bav063 [2015-07-11; online 2015-07-11]

Affiliated researcher

PubMed DOI Crossref

Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol.

Hacke M, Björkholm P, Hellwig A, ..., Wieland F, Ernst AM

Nat Commun 6 (-) 7688 [2015-07-09; online 2015-07-09]

Affiliated researcher

PubMed DOI Crossref

The SWI/SNF Subunit INI1 Contains an N-Terminal Winged Helix DNA Binding Domain that Is a Target for Mutations in Schwannomatosis.

Allen MD, Freund SM, Zinzalla G, Bycroft M

Structure 23 (7) 1344-1349 [2015-07-07; online 2015-06-11]

Affiliated researcher

PubMed DOI Crossref

Formation of Silver Nanostructures by Rolling Circle Amplification Using Boranephosphonate-Modified Nucleotides.

Russell C, Roy S, Ganguly S, ..., Caruthers MH, Nilsson M

Anal. Chem. 87 (13) 6660-6666 [2015-07-07; online 2015-06-22]

Affiliated researcher

PubMed DOI Crossref

Chromosomal copy number variation reveals differential levels of genomic plasticity in distinct Trypanosoma cruzi strains.

Reis-Cunha JL, Rodrigues-Luiz GF, Valdivia HO, ..., Vasconcelos AT, Bartholomeu DC

BMC Genomics 16 (-) 499 [2015-07-04; online 2015-07-04]

Affiliated researcher

PubMed DOI Crossref

Small RNAs in bacteria and archaea: who they are, what they do, and how they do it.

Wagner EGH, Romby P

Adv. Genet. 90 (-) 133-208 [2015-07-03; online 2015-07-03]

Affiliated researcher

PubMed DOI Crossref

Nutritional Control of DNA Replication Initiation through the Proteolysis and Regulated Translation of DnaA

Leslie DJ, Heinen C, Schramm FD, ..., Laub MT, Jonas K

PLoS Genet 11 (7) e1005342 [2015-07-02; online 2015-07-02]

Kristina Jonas SciLifeLab Fellow

PubMed DOI Crossref

Discovery of GPCR Ligands by Molecular Docking Screening: Novel Opportunities Provided by Crystal Structures.

Rodríguez D, Ranganathan A, Carlsson J

CTMC 15 (24) 2484-2503 [2015-07-02; online 2015-07-02]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer.

Dietlein F, Kalb B, Jokic M, ..., Thomas RK, Reinhardt HC

Cell 162 (1) 146-159 [2015-07-02; online 2015-07-04]

Affiliated researcher

PubMed DOI Crossref

The TOPCONS web server for consensus prediction of membrane protein topology and signal peptides.

Tsirigos KD, Peters C, Shu N, Käll L, Elofsson A

Nucleic Acids Res. 43 (W1) W401-W407 [2015-07-01; online 2015-05-12]

Affiliated researcher

PubMed DOI Crossref

Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals.

Cedervall J, Zhang Y, Huang H, ..., Dimberg A, Olsson AK

Cancer Res. 75 (13) 2653-2662 [2015-07-01; online 2015-06-12]

Affiliated researcher

PubMed DOI Crossref

Critical Role of Histone Turnover in Neuronal Transcription and Plasticity.

Maze I, Wenderski W, Noh KM, ..., Molina H, Allis CD

Neuron 87 (1) 77-94 [2015-07-01; online 2015-07-04]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes.

Fall T, Xie W, Poon W, ..., Frayling TM, Ingelsson E

Diabetes 64 (7) 2676-2684 [2015-07-00; online 2015-05-06]

Affiliated researcher

PubMed DOI Crossref

Toward Rare Blood Cell Preservation for RNA Sequencing.

Vickovic S, Ahmadian A, Lewensohn R, Lundeberg J

J Mol Diagn 17 (4) 352-359 [2015-07-00; online 2015-05-16]

Affiliated researcher Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

The Nuclear PolyA-Binding Protein Nab2p Is Essential for mRNA Production

Schmid M, Olszewski P, Pelechano V, ..., Steinmetz LM, Jensen TH

Cell Reports 12 (1) 128-139 [2015-07-00; online 2015-07-00]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Rediscovery rate estimation for assessing the validation of significant findings in high-throughput studies.

Ganna A, Lee D, Ingelsson E, Pawitan Y

Brief. Bioinformatics 16 (4) 563-575 [2015-07-00; online 2014-09-24]

Affiliated researcher

PubMed DOI Crossref

Quality of life in patients with venous thromboembolism and atrial fibrillation treated with coumarin anticoagulants.

Marvig CL, Verhoef TI, de Boer A, ..., Maitland-van der Zee AH, EU-PACT consortium

Thromb. Res. 136 (1) 69-75 [2015-07-00; online 2015-04-25]

Affiliated researcher

PubMed DOI Crossref

Polymorphisms in DCDC2 and S100B associate with developmental dyslexia.

Matsson H, Huss M, Persson H, ..., Peyrard-Janvid M, Kere J

J. Hum. Genet. 60 (7) 399-401 [2015-07-00; online 2015-04-16]

Affiliated researcher

PubMed DOI Crossref

Neuroproteomics tools in clinical practice.

Shevchenko G, Konzer A, Musunuri S, Bergquist J

Biochim. Biophys. Acta 1854 (7) 705-717 [2015-07-00; online 2015-02-10]

Affiliated researcher

PubMed DOI Crossref

Metabolite profiling of microfluidic cell culture conditions for droplet based screening.

Bjork SM, Sjostrom SL, Andersson-Svahn H, Joensson HN

Biomicrofluidics 9 (4) 044128 [2015-07-00; online 2015-08-31]

Affiliated researcher

PubMed DOI Crossref

Marginally hydrophobic transmembrane α-helices shaping membrane protein folding.

De Marothy MT, Elofsson A

Protein Sci. 24 (7) 1057-1074 [2015-07-00; online 2015-05-30]

Affiliated researcher

PubMed DOI Crossref

Insertion of exogenous epitopes in the E3-19K of oncolytic adenoviruses to enhance TAP-independent presentation and immunogenicity.

Rodríguez-García A, Svensson E, Gil-Hoyos R, ..., Loskog AS, Alemany R

Gene Ther. 22 (7) 596-601 [2015-07-00; online 2015-05-21]

Affiliated researcher

PubMed DOI Crossref

High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.

Varshney GK, Pei W, LaFave MC, ..., Ledin J, Burgess SM

Genome Res. 25 (7) 1030-1042 [2015-07-00; online 2015-06-05]

Affiliated researcher

PubMed DOI Crossref

Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample.

Ng E, Salihovic S, Lind PM, ..., Morris AP, Lind L

Environ. Res. 140 (-) 95-101 [2015-07-00; online 2015-04-02]

Affiliated researcher

PubMed DOI Crossref

Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro.

Heiss M, Hellström M, Kalén M, ..., Augustin HG, Korff T

FASEB J. 29 (7) 3076-3084 [2015-07-00; online 2015-04-09]

Affiliated researcher

PubMed DOI Crossref

Disentangling seasonal bacterioplankton population dynamics by high-frequency sampling.

Lindh MV, Sjöstedt J, Andersson AF, ..., Legrand C, Pinhassi J

Environ. Microbiol. 17 (7) 2459-2476 [2015-07-00; online 2015-01-27]

Affiliated researcher DDLS Fellow Luisa Hugerth

PubMed DOI Crossref

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.

Horikoshi M, Mӓgi R, van de Bunt M, ..., Morris AP, ENGAGE Consortium

PLoS Genet 11 (7) e1005230 [2015-07-00; online 2015-07-01]

Affiliated researcher

PubMed DOI Crossref

Comparative sequence analysis suggests a conserved gating mechanism for TRP channels

Palovcak E, Delemotte L, Klein ML, Carnevale V

J Gen Physiol 146 (1) 37-50 [2015-07-00; online 2015-06-15]

Lucie Delemotte SciLifeLab Fellow

DOI Crossref

Chondroitin Sulfate-Coated DNA-Nanoplexes Enhance Transfection Efficiency by Controlling Plasmid Release from Endosomes: A New Insight into Modulating Nonviral Gene Transfection

Yan H, Oommen OP, Yu D, ..., Qian H, Varghese OP

Adv. Funct. Mater. 25 (25) 3907-3915 [2015-07-00; online 2015-05-18]

Affiliated researcher

PubMed DOI Crossref

BBMRI-ERIC as a resource for pharmaceutical and life science industries: the development of biobank-based Expert Centres.

van Ommen GJ, Törnwall O, Bréchot C, ..., Litton JE, Zatloukal K

Eur. J. Hum. Genet. 23 (7) 893-900 [2015-07-00; online 2014-11-19]

Affiliated researcher

PubMed DOI Crossref

Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate.

Trésaugues L, Lundbäck T, Welin M, ..., Gräslund S, Nordlund P

PLoS ONE 10 (6) e0131507 [2015-06-29; online 2015-06-29]

Affiliated researcher

PubMed DOI Crossref

High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort.

Sorbye H, Dragomir A, Sundström M, ..., Qvortrup C, Glimelius B

PLoS ONE 10 (6) e0131046 [2015-06-29; online 2015-06-29]

Affiliated researcher

PubMed DOI Crossref

A complete map of potential pathogenicity markers of avian influenza virus subtype H5 predicted from 11 expressed proteins.

Khaliq Z, Leijon M, Belák S, Komorowski J

BMC Microbiol. 15 (-) 128 [2015-06-26; online 2015-06-26]

Affiliated researcher

PubMed DOI Crossref

Αlpha 2a-Adrenoceptor Gene Expression and Early Life Stress-Mediated Propensity to Alcohol Drinking in Outbred Rats.

Comasco E, Todkar A, Granholm L, Nilsson KW, Nylander I

Int J Environ Res Public Health 12 (7) 7154-7171 [2015-06-25; online 2015-06-25]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling.

Lindskog C, Linné J, Fagerberg L, ..., Pontén F, Uhlén M

BMC Genomics 16 (1) 475 [2015-06-25; online 2015-06-25]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Gene expression analysis of skin grafts and cultured keratinocytes using synthetic RNA normalization reveals insights into differentiation and growth control.

Katayama S, Skoog T, Jouhilahti EM, ..., Kankuri E, Kere J

BMC Genomics 16 (-) 476 [2015-06-25; online 2015-06-25]

Affiliated researcher

DOI Crossref

Clinical significance of expression of DNA Helicase RecQL1 in cervical carcinoma

Wu L, Yang H, Gao X, ..., Zhou F, Zhou Y

Medical Journal of Wuhan University 36 (4) 506-509 [2015-06-24; online 2015-06-24]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

Transcriptional modulator ZBED6 affects cell cycle and growth of human colorectal cancer cells.

Akhtar Ali M, Younis S, Wallerman O, ..., Andersson L, Sjöblom T

Proc. Natl. Acad. Sci. U.S.A. 112 (25) 7743-7748 [2015-06-23; online 2015-06-08]

Affiliated researcher

PubMed DOI Crossref

Linked genetic variants on chromosome 10 control ear morphology and body mass among dog breeds.

Webster MT, Kamgari N, Perloski M, ..., Pielberg G, Lindblad-Toh K

BMC Genomics 16 (-) 474 [2015-06-23; online 2015-06-23]

Affiliated researcher

PubMed DOI Crossref

Transforming growth factor β and bone morphogenetic protein actions in brain tumors.

Caja L, Bellomo C, Moustakas A

FEBS Lett. 589 (14) 1588-1597 [2015-06-22; online 2015-05-06]

Affiliated researcher

PubMed DOI Crossref

Force Field Benchmark of Organic Liquids. 2. Gibbs Energy of Solvation.

Zhang J, Tuguldur B, van der Spoel D

J Chem Inf Model 55 (6) 1192-1201 [2015-06-22; online 2015-06-03]

Affiliated researcher

PubMed DOI Crossref

Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth.

Alexeyenko A, Alkasalias T, Pavlova T, ..., Guven H, Klein G

J. Exp. Clin. Cancer Res. 34 (-) 62 [2015-06-18; online 2015-06-18]

Affiliated researcher

PubMed DOI Crossref

Transglutaminase 4 as a prostate autoantigen in male subfertility.

Landegren N, Sharon D, Shum AK, ..., Snyder M, Kämpe O

Sci Transl Med 7 (292) 292ra101 [2015-06-17; online 2015-06-19]

Affiliated researcher

PubMed DOI Crossref

Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome.

Gu Urban GJ, Friedman M, Ren P, ..., Landegren U, Kamali-Moghaddam M

Sci Rep 5 (-) 11196 [2015-06-16; online 2015-06-16]

Affiliated researcher

PubMed DOI Crossref

Mobility-based prediction of hydration structures of protein surfaces.

Jeszenői N, Horváth I, Bálint M, van der Spoel D, Hetényi C

Bioinformatics 31 (12) 1959-1965 [2015-06-15; online 2015-02-13]

Affiliated researcher

PubMed DOI Crossref

IFN-α production by plasmacytoid dendritic cell associations with polymorphisms in gene loci related to autoimmune and inflammatory diseases.

Berggren O, Alexsson A, Morris DL, ..., Rönnblom L, Eloranta ML

Hum. Mol. Genet. 24 (12) 3571-3581 [2015-06-15; online 2015-03-16]

Affiliated researcher

PubMed DOI Crossref

Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex.

Sjöstedt E, Fagerberg L, Hallström BM, ..., Uhlén M, Mulder J

PLoS ONE 10 (6) e0130028 [2015-06-15; online 2015-06-15]

Affiliated researcher

PubMed DOI Crossref

Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals.

Nead KT, Li A, Wehner MR, ..., Anand SS, Meyre D

Hum. Mol. Genet. 24 (12) 3582-3594 [2015-06-15; online 2015-03-17]

Affiliated researcher

PubMed DOI Crossref

Two steps forward, one step back: successes and failures in structure-based discovery of GPCR ligands.

Carlsson J

Springerplus 4 (Suppl 1) L5 [2015-06-12; online 2015-06-12]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Proximity-dependent initiation of hybridization chain reaction.

Koos B, Cane G, Grannas K, ..., Kamali-Moghaddam M, Söderberg O

Nat Commun 6 (-) 7294 [2015-06-12; online 2015-06-12]

Affiliated researcher

PubMed DOI Crossref

Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response.

O'Callaghan P, Li JP, Lannfelt L, Lindahl U, Zhang X

J. Biol. Chem. 290 (24) 14904-14914 [2015-06-12; online 2015-04-13]

Affiliated researcher

PubMed DOI Crossref

Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells.

Elsässer SJ, Noh KM, Diaz N, Allis CD, Banaszynski LA

Nature 522 (7555) 240-244 [2015-06-11; online 2015-05-04]

Affiliated researcher SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Phasing of single DNA molecules by massively parallel barcoding.

Borgström E, Redin D, Lundin S, ..., Andersson AF, Ahmadian A

Nat Commun 6 (-) 7173 [2015-06-09; online 2015-06-09]

Affiliated researcher

PubMed DOI Crossref

Molecular simulation workflows as parallel algorithms: the execution engine of Copernicus, a distributed high-performance computing platform.

Pronk S, Pouya I, Lundborg M, ..., Kasson PM, Lindahl E

J Chem Theory Comput 11 (6) 2600-2608 [2015-06-09; online 2015-11-18]

Affiliated researcher

PubMed DOI Crossref

A coarse-grained simulation study of the structures, energetics, and dynamics of linear and circular DNA with its ions.

Naômé A, Laaksonen A, Vercauteren DP

J Chem Theory Comput 11 (6) 2813-2826 [2015-06-09; online 2015-05-14]

Affiliated researcher

PubMed DOI Crossref

The mammalian alcohol dehydrogenase genome shows several gene duplications and gene losses resulting in a large set of different enzymes including pseudoenzymes.

Östberg LJ, Persson B, Höög JO

Chem. Biol. Interact. 234 (-) 80-84 [2015-06-05; online 2014-12-03]

Affiliated researcher

PubMed DOI Crossref

Next-generation pathology--surveillance of tumor microecology.

Koos B, Kamali-Moghaddam M, David L, ..., Wählby C, Söderberg O

J. Mol. Biol. 427 (11) 2013-2022 [2015-06-05; online 2015-02-26]

Affiliated researcher

PubMed DOI Crossref

Alcohol dehydrogenase, SDR and MDR structural stages, present update and altered era.

Jörnvall H, Landreh M, Östberg LJ

Chem. Biol. Interact. 234 (-) 75-79 [2015-06-05; online 2014-10-29]

Affiliated researcher

PubMed DOI Crossref

Excessive antigen reactivity may underlie the clinical aggressiveness of chronic lymphocytic leukemia stereotyped subset #8.

Gounari M, Ntoufa S, Apollonio B, ..., Stamatopoulos K, Ghia P

Blood 125 (23) 3580-3587 [2015-06-04; online 2015-04-21]

Affiliated researcher

PubMed DOI Crossref

Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene.

Dorshorst B, Henegar C, Liao X, ..., Barsh GS, Andersson L

PLoS ONE 10 (6) e0128969 [2015-06-04; online 2015-06-04]

Affiliated researcher

PubMed DOI Crossref

A quantitative assessment of the Hadoop framework for analyzing massively parallel DNA sequencing data.

Siretskiy A, Sundqvist T, Voznesenskiy M, Spjuth O

Gigascience 4 (-) 26 [2015-06-04; online 2015-06-04]

Affiliated researcher

PubMed DOI Crossref

Single-cell polyadenylation site mapping reveals 3' isoform choice variability.

Velten L, Anders S, Pekowska A, ..., Pelechano V, Steinmetz LM

Mol Syst Biol 11 (6) 812 [2015-06-03; online 2015-06-03]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Processing of protein ADP-ribosylation by Nudix hydrolases.

Palazzo L, Thomas B, Jemth AS, ..., Helleday T, Ahel I

Biochem. J. 468 (2) 293-301 [2015-06-01; online 2015-03-20]

Affiliated researcher

PubMed DOI Crossref

Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia.

Mansouri L, Sutton LA, Ljungström V, ..., Nilsson M, Rosenquist R

J. Exp. Med. 212 (6) 833-843 [2015-06-01; online 2015-05-18]

Affiliated researcher

PubMed DOI Crossref

Widespread Co-translational RNA Decay Reveals Ribosome Dynamics

Pelechano V, Wei W, Steinmetz LM

Cell 161 (6) 1400-1412 [2015-06-00; online 2015-06-00]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Tumor vessel up-regulation of INSR revealed by single-cell expression analysis of the tyrosine kinome and phosphatome in human cancers.

Kiflemariam S, Ljungström V, Pontén F, Sjöblom T

Am. J. Pathol. 185 (6) 1600-1609 [2015-06-00; online 2015-04-10]

Affiliated researcher

PubMed DOI Crossref

Treg-cell depletion promotes chemokine production and accumulation of CXCR3(+) conventional T cells in intestinal tumors.

Akeus P, Langenes V, Kristensen J, ..., Raghavan S, Quiding-Järbrink M

Eur. J. Immunol. 45 (6) 1654-1666 [2015-06-00; online 2015-04-14]

Astrid von Mentzer DDLS Fellow

PubMed DOI Crossref

Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2.

de Miranda NF, van Dinther M, van den Akker BE, ..., ten Dijke P, Morreau H

Gastroenterology 148 (7) 1427-37.e8 [2015-06-00; online 2015-02-28]

Affiliated researcher

PubMed DOI Crossref

The impact of low-frequency and rare variants on lipid levels.

Surakka I, Horikoshi M, Mägi R, ..., Ripatti S, ENGAGE Consortium

Nat. Genet. 47 (6) 589-597 [2015-06-00; online 2015-05-11]

Affiliated researcher

PubMed DOI Crossref

The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.

Dahlman I, Sinha I, Gao H, ..., Dahlman-Wright K, Arner P

Int J Obes (Lond) 39 (6) 910-919 [2015-06-00; online 2015-03-18]

Affiliated researcher

PubMed DOI Crossref

Significance of archaeal nitrification in hypoxic waters of the Baltic Sea.

Berg C, Vandieken V, Thamdrup B, Jürgens K

ISME J 9 (6) 1319-1332 [2015-06-00; online 2014-11-25]

Affiliated researcher

PubMed DOI Crossref

Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents.

Russo F, Gising J, Åkerbladh L, ..., Karlén A, Larhed M

ChemistryOpen 4 (3) 342-362 [2015-06-00; online 2015-04-17]

Affiliated researcher

PubMed DOI Crossref

Non-reciprocal Interspecies Hybridization Barriers in the Capsella Genus Are Established in the Endosperm.

Rebernig CA, Lafon-Placette C, Hatorangan MR, Slotte T, Köhler C

PLoS Genet 11 (6) e1005295 [2015-06-00; online 2015-06-18]

SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

NLRC4 Inflammasome Is an Important Regulator of Interleukin-18 Levels in Patients With Acute Coronary Syndromes: Genome-Wide Association Study in the PLATelet inhibition and patient Outcomes Trial (PLATO).

Johansson Å, Eriksson N, Becker RC, ..., Siegbahn A, PLATO Investigators

Circ Cardiovasc Genet 8 (3) 498-506 [2015-06-00; online 2015-03-06]

Affiliated researcher

PubMed DOI Crossref

Multiple Changes of Gene Expression and Function Reveal Genomic and Phenotypic Complexity in SLE-like Disease.

Wilbe M, Kozyrev SV, Farias FH, ..., Hansson-Hamlin H, Lindblad-Toh K

PLoS Genet 11 (6) e1005248 [2015-06-00; online 2015-06-09]

Affiliated researcher

PubMed DOI Crossref

Molecular evidence for antigen drive in the natural history of mantle cell lymphoma.

Xochelli A, Sutton LA, Agathangelidis A, ..., Belessi C, Stamatopoulos K

Am. J. Pathol. 185 (6) 1740-1748 [2015-06-00; online 2015-04-02]

Affiliated researcher

PubMed DOI Crossref

Microbial metagenomics in the Baltic Sea: Recent advancements and prospects for environmental monitoring.

Ininbergs K, Bergman B, Larsson J, Ekman M

Ambio 44 Suppl 3 (-) 439-450 [2015-06-00; online 2015-05-30]

Affiliated researcher

DOI Crossref

MATHEMATICAL MODELING OF BEHÇET'S DISEASE: A DYNAMICAL SYSTEMS APPROACH

ERDEM C, BOZKURT Y, ERMAN B, GÜL A, DEMIR A

J. Biol. Syst. 23 (02) 231-257 [2015-06-00; online 2015-05-28]

Cemal Erdem DDLS Fellow

PubMed DOI Crossref

Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma.

Edqvist PH, Huvila J, Forsström B, ..., Pontén F, Auranen A

Gynecol. Oncol. 137 (3) 529-537 [2015-06-00; online 2015-04-07]

Affiliated researcher

PubMed DOI Crossref

Human adaptation to arsenic-rich environments.

Schlebusch CM, Gattepaille LM, Engström K, ..., Jakobsson M, Broberg K

Mol. Biol. Evol. 32 (6) 1544-1555 [2015-06-00; online 2015-03-03]

Affiliated researcher

PubMed DOI Crossref

Exome sequencing of contralateral breast cancer identifies metastatic disease.

Klevebring D, Lindberg J, Rockberg J, ..., Sandberg M, Czene K

Breast Cancer Res. Treat. 151 (2) 319-324 [2015-06-00; online 2015-04-29]

Affiliated researcher

PubMed DOI Crossref

Effect of host plant and immune challenge on the levels of chemosensory and odorant-binding proteins in caterpillar salivary glands.

Celorio-Mancera Mde L, Ytterberg AJ, Rutishauser D, Janz N, Zubarev RA

Insect Biochem. Mol. Biol. 61 (-) 34-45 [2015-06-00; online 2015-04-29]

Affiliated researcher

PubMed DOI Crossref

Dendritic cell regulation of NK-cell responses involves lymphotoxin-α, IL-12, and TGF-β.

Sarhan D, Palma M, Mao Y, ..., Österborg A, Lundqvist A

Eur. J. Immunol. 45 (6) 1783-1793 [2015-06-00; online 2015-04-17]

SciLifeLab Fellow Yumeng Mao

PubMed DOI Crossref

CK1δ restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1α/ARNT complex formation.

Kourti M, Ikonomou G, Giakoumakis NN, ..., Simos G, Mylonis I

Cell. Signal. 27 (6) 1129-1140 [2015-06-00; online 2015-03-03]

Affiliated researcher

PubMed DOI Crossref

Antibiotic resistance genes in the environment: prioritizing risks.

Bengtsson-Palme J, Larsson DG

Nat. Rev. Microbiol. 13 (6) 396 [2015-06-00; online 2015-04-27]

DDLS Fellow Johan Bengtsson-Palme

DOI Crossref

A chemoenzymatic approach toward the preparation of site-specific antibody–drug conjugates

Cai X, Janda KD

Tetrahedron Letters 56 (23) 3172-3175 [2015-06-00; online 2015-06-00]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants.

Allum F, Shao X, Guénard F, ..., Pastinen T, Grundberg E

Nat Commun 6 (-) 7211 [2015-05-29; online 2015-05-29]

Affiliated researcher

PubMed DOI Crossref

Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.

Swaminathan B, Thorleifsson G, Jöud M, ..., Thorsteinsdóttir U, Nilsson B

Nat Commun 6 (1) 7213 [2015-05-26; online 2015-05-26]

Affiliated researcher

PubMed DOI Crossref

Purification of functionalized DNA origami nanostructures.

Shaw A, Benson E, Högberg B

ACS Nano 9 (5) 4968-4975 [2015-05-26; online 2015-05-12]

Erik Benson SciLifeLab Fellow

PubMed DOI Crossref

Estrogen Receptor β2 Induces Hypoxia Signature of Gene Expression by Stabilizing HIF-1α in Prostate Cancer.

Dey P, Velazquez-Villegas LA, Faria M, ..., Gustafsson JÅ, Ström AM

PLoS ONE 10 (5) e0128239 [2015-05-26; online 2015-05-26]

Affiliated researcher

PubMed DOI Crossref

Phenotypic variability in a seven-generation Swedish family segregating autosomal dominant hearing impairment due to a novel EYA4 frameshift mutation.

Frykholm C, Klar J, Arnesson H, ..., Tranebjærg L, Rendtorff ND

Gene 563 (1) 10-16 [2015-05-25; online 2015-02-11]

Affiliated researcher

PubMed DOI Crossref

Understanding thio-effects in simple phosphoryl systems: role of solvent effects and nucleophile charge.

Carvalho AT, O'Donoghue AC, Hodgson DR, Kamerlin SC

Org. Biomol. Chem. 13 (19) 5391-5398 [2015-05-21; online 2015-03-24]

Affiliated researcher

PubMed DOI Crossref

Cationic PTD/CPP-mediated macromolecular delivery: charging into the cell.

Lönn P, Dowdy SF

Expert Opin Drug Deliv 12 (10) 1627-1636 [2015-05-20; online 2015-05-20]

Affiliated researcher

PubMed DOI Crossref

Metabolic dependencies drive species co-occurrence in diverse microbial communities

Zelezniak A, Andrejev S, Ponomarova O, ..., Bork P, Patil KR

Proceedings of the National Academy of Sciences 112 (20) 6449-6454 [2015-05-19; online 2015-05-04]

Aleksej Zelezniak SciLifeLab Fellow

PubMed DOI Crossref

Spectral imaging to measure heterogeneity in membrane lipid packing.

Sezgin E, Waithe D, Bernardino de la Serna J, Eggeling C

Chemphyschem 16 (7) 1387-1394 [2015-05-18; online 2015-03-05]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

CGGBP1 mitigates cytosine methylation at repetitive DNA sequences.

Agarwal P, Collier P, Fritz MH, ..., Westermark B, Singh U

BMC Genomics 16 (-) 390 [2015-05-16; online 2015-05-16]

Affiliated researcher

PubMed DOI Crossref

Obesity, metabolic syndrome and risk of atrial fibrillation: a Swedish, prospective cohort study.

Nyström PK, Carlsson AC, Leander K, ..., Hellenius ML, Gigante B

PLoS ONE 10 (5) e0127111 [2015-05-15; online 2015-05-15]

Affiliated researcher

PubMed DOI Crossref

Digital quantification of rolling circle amplified single DNA molecules in a resistive pulse sensing nanopore.

Kühnemund M, Nilsson M

Biosens Bioelectron 67 (-) 11-17 [2015-05-15; online 2014-06-24]

Affiliated researcher

PubMed DOI Crossref

Differential protein expression profiles of cyst fluid from papillary thyroid carcinoma and benign thyroid lesions.

Dinets A, Pernemalm M, Kjellin H, ..., Lehtiö J, Höög A

PLoS ONE 10 (5) e0126472 [2015-05-15; online 2015-05-15]

Affiliated researcher

PubMed DOI Crossref

Complex archaea that bridge the gap between prokaryotes and eukaryotes.

Spang A, Saw JH, Jørgensen SL, ..., Guy L, Ettema TJG

Nature 521 (7551) 173-179 [2015-05-14; online 2015-05-06]

Affiliated researcher

PubMed DOI Crossref

The Shepherds' Tale: A Genome-Wide Study across 9 Dog Breeds Implicates Two Loci in the Regulation of Fructosamine Serum Concentration in Belgian Shepherds.

Forsberg SK, Kierczak M, Ljungvall I, ..., Lindblad-Toh K, Höglund K

PLoS ONE 10 (5) e0123173 [2015-05-13; online 2015-05-13]

Affiliated researcher

PubMed DOI Crossref

Proteome- and transcriptome-driven reconstruction of the human myocyte metabolic network and its use for identification of markers for diabetes.

Väremo L, Scheele C, Broholm C, ..., Pedersen BK, Nielsen J

Cell Reports 11 (6) 921-933 [2015-05-12; online 2015-04-30]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Probe Region Expression Estimation for RNA-Seq Data for Improved Microarray Comparability.

Uziela K, Honkela A

PLoS ONE 10 (5) e0126545 [2015-05-12; online 2015-05-12]

Affiliated researcher

PubMed DOI Crossref

Vinylic MIDA Boronates: New Building Blocks for the Synthesis of Aza-Heterocycles.

Llona-Minguez S, Desroses M, Ghassemian A, ..., Scobie M, Helleday T

Chemistry 21 (20) 7394-7398 [2015-05-11; online 2015-03-25]

Affiliated researcher

PubMed DOI Crossref

The T cell receptor resides in ordered plasma membrane nanodomains that aggregate upon patching of the receptor.

Dinic J, Riehl A, Adler J, Parmryd I

Sci Rep 5 (-) 10082 [2015-05-08; online 2015-05-08]

Affiliated researcher

PubMed DOI Crossref

Human genomics. Effect of predicted protein-truncating genetic variants on the human transcriptome.

Rivas MA, Pirinen M, Conrad DF, ..., Lappalainen T, MacArthur DG

Science (New York, N.Y.) 348 (6235) 666-669 [2015-05-08; online 2015-05-09]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

Functionally Structured Genomes in Lactobacillus kunkeei Colonizing the Honey Crop and Food Products of Honeybees and Stingless Bees.

Tamarit D, Ellegaard KM, Wikander J, ..., Vásquez A, Andersson SG

Genome Biol Evol 7 (6) 1455-1473 [2015-05-06; online 2015-05-06]

Affiliated researcher

PubMed DOI Crossref

Deconvoluting Protein (Un)folding Structural Ensembles Using X-Ray Scattering, Nuclear Magnetic Resonance Spectroscopy and Molecular Dynamics Simulation.

Nasedkin A, Marcellini M, Religa TL, ..., van der Spoel D, Davidsson J

PLoS ONE 10 (5) e0125662 [2015-05-06; online 2015-05-06]

Affiliated researcher

PubMed DOI Crossref

Somatostatin Analogs Treated Small Intestinal Neuroendocrine Tumor Patients Circulating MicroRNAs.

Li SC, Khan M, Caplin M, ..., Öberg K, Giandomenico V

PLoS ONE 10 (5) e0125553 [2015-05-05; online 2015-05-05]

Affiliated researcher

PubMed DOI Crossref

Intestinal dysbiosis in children with short bowel syndrome is associated with impaired outcome.

Engstrand Lilja H, Wefer H, Nyström N, Finkel Y, Engstrand L

Microbiome 3 (-) 18 [2015-05-04; online 2015-05-04]

Affiliated researcher

PubMed DOI Crossref

RhoD is a Golgi component with a role in anterograde protein transport from the ER to the plasma membrane.

Blom M, Reis K, Nehru V, ..., Gad AK, Aspenström P

Exp. Cell Res. 333 (2) 208-219 [2015-05-01; online 2015-03-05]

Affiliated researcher

PubMed DOI Crossref

Coordinated expression of DNAM-1 and LFA-1 in educated NK cells.

Enqvist M, Ask EH, Forslund E, ..., Önfelt B, Malmberg KJ

J. Immunol. 194 (9) 4518-4527 [2015-05-01; online 2015-03-30]

Affiliated researcher

PubMed DOI Crossref

A systematic investigation of the contribution of genetic variation within the MHC region to HPV seropositivity.

Chen D, Gaborieau V, Zhao Y, ..., Brennan P, McKay JD

Hum. Mol. Genet. 24 (9) 2681-2688 [2015-05-01; online 2015-01-23]

Affiliated researcher

PubMed DOI Crossref

Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties.

Nordin JZ, Lee Y, Vader P, ..., Wood MJ, El Andaloussi S

Nanomedicine 11 (4) 879-883 [2015-05-00; online 2015-02-04]

Affiliated researcher

PubMed DOI Crossref

Tracking the origin of metastatic prostate cancer.

Lindberg J, Kristiansen A, Wiklund P, Grönberg H, Egevad L

Eur. Urol. 67 (5) 819-822 [2015-05-00; online 2014-09-22]

Affiliated researcher

PubMed DOI Crossref

The tyrosine kinase inhibitors imatinib and dasatinib reduce myeloid suppressor cells and release effector lymphocyte responses.

Christiansson L, Söderlund S, Mangsbo S, ..., Loskog A, Olsson-Strömberg U

Mol. Cancer Ther. 14 (5) 1181-1191 [2015-05-00; online 2015-03-11]

Affiliated researcher

PubMed DOI Crossref

The effect of macrocyclic chelators on the targeting properties of the 68Ga-labeled gastrin releasing peptide receptor antagonist PEG2-RM26.

Varasteh Z, Mitran B, Rosenström U, ..., Tolmachev V, Orlova A

Nucl. Med. Biol. 42 (5) 446-454 [2015-05-00; online 2014-12-20]

Affiliated researcher

PubMed DOI Crossref

Recent advances in QM/MM free energy calculations using reference potentials.

Duarte F, Amrein BA, Blaha-Nelson D, Kamerlin SCL

Biochim. Biophys. Acta 1850 (5) 954-965 [2015-05-00; online 2014-07-16]

Affiliated researcher

PubMed DOI Crossref

Quantifying the impact of transporters on cellular drug permeability.

Matsson P, Fenu LA, Lundquist P, ..., Kansy M, Artursson P

Trends Pharmacol. Sci. 36 (5) 255-262 [2015-05-00; online 2015-03-19]

Affiliated researcher

PubMed DOI Crossref

Predictors of recurrent cellulitis in five years. Clinical risk factors and the role of PTX3 and CRP.

Karppelin M, Siljander T, Aittoniemi J, ..., Vuopio J, Syrjänen J

J. Infect. 70 (5) 467-473 [2015-05-00; online 2014-11-15]

Affiliated researcher

PubMed DOI Crossref

Mass-spectrometry-based characterization of oxidations in proteins.

Artemenko K, Mi J, Bergquist J

Free Radic. Res. 49 (5) 477-493 [2015-05-00; online 2015-04-17]

Affiliated researcher

PubMed DOI Crossref

ITS1: a DNA barcode better than ITS2 in eukaryotes?

Wang XC, Liu C, Huang L, ..., Cai D, Li JQ

Mol Ecol Resour 15 (3) 573-586 [2015-05-00; online 2014-09-24]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers.

Watkins J, Weekes D, Shah V, ..., Grigoriadis A, Tutt AN

Cancer Discov 5 (5) 488-505 [2015-05-00; online 2015-03-13]

Affiliated researcher

PubMed DOI Crossref

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.

Coffee and Caffeine Genetics Consortium , Cornelis MC, Byrne EM, ..., van Dam RM, Chasman DI

Mol. Psychiatry 20 (5) 647-656 [2015-05-00; online 2014-10-07]

Affiliated researcher

PubMed DOI Crossref

Evolutionary histories of transposable elements in the genome of the largest living marsupial carnivore, the Tasmanian devil.

Gallus S, Hallström BM, Kumar V, ..., Schumann GG, Nilsson MA

Mol. Biol. Evol. 32 (5) 1268-1283 [2015-05-00; online 2015-01-28]

Affiliated researcher

PubMed DOI Crossref

Electrolyte disorders assessment in solid tumor patients treated with anti-EGFR monoclonal antibodies: a pooled analysis of 25 randomized clinical trials.

Wang Q, Qi Y, Zhang D, ..., Zhou F, Zhou Y

Tumour Biol. 36 (5) 3471-3482 [2015-05-00; online 2014-12-28]

DDLS Fellow Qiaoli Wang

PubMed

Diagnostic urinary proteome profile for immunoglobulin a nephropathy.

Samavat S, Kalantari S, Nafar M, ..., Parvin M, Zubarev RA

Iran J Kidney Dis 9 (3) 239-248 [2015-05-00; online 2015-05-10]

Affiliated researcher

DOI Crossref

Cu(OAc)2-Catalysed Oxidative Dual C-H/N-H Activation of Terminal Alkynes andN-Deprotected Sulfonimidamides: An Easy Access toN-Alkynylated Sulfonimidamides

Nandi GC, Kota SR, Naicker T, ..., Kruger HG, Arvidsson PI

Eur. J. Org. Chem. 2015 (13) 2861-2867 [2015-05-00; online 2015-03-17]

Affiliated researcher

PubMed DOI Crossref

Computational modeling of the N-terminus of the human dopamine transporter and its interaction with PIP2 -containing membranes.

Khelashvili G, Doktorova M, Sahai MA, ..., Shi L, Weinstein H

Proteins 83 (5) 952-969 [2015-05-00; online 2015-03-25]

DDLS Fellow Milka Doktorova

PubMed DOI Crossref

Autoantibody response against NALP5/MATER in primary ovarian insufficiency and in autoimmune Addison's disease.

Brozzetti A, Alimohammadi M, Morelli S, ..., Falorni A, Italian Addison Network

J. Clin. Endocrinol. Metab. 100 (5) 1941-1948 [2015-05-00; online 2015-03-03]

Affiliated researcher

PubMed DOI Crossref

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors.

Fall T, Hägg S, Ploner A, ..., Ingelsson E, ENGAGE Consortium

Diabetes 64 (5) 1841-1852 [2015-05-00; online 2015-02-23]

Affiliated researcher

PubMed DOI Crossref

African origin for Madagascan dogs revealed by mtDNA analysis.

Ardalan A, Oskarsson MC, van Asch B, Rabakonandriania E, Savolainen P

R Soc Open Sci 2 (5) 140552 [2015-05-00; online 2015-05-20]

Affiliated researcher

PubMed DOI Crossref

'True' null allele detection in microsatellite loci: a comparison of methods, assessment of difficulties and survey of possible improvements.

Dąbrowski MJ, Bornelöv S, Kruczyk M, Baltzer N, Komorowski J

Mol Ecol Resour 15 (3) 477-488 [2015-05-00; online 2014-09-26]

Affiliated researcher

PubMed DOI Crossref

Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery.

Mørch Ý, Hansen R, Berg S, ..., de Lange Davies C, Stenstad PM

Contrast Media Mol Imaging 10 (5) 356-366 [2015-04-30; online 2015-04-30]

Affiliated researcher

PubMed DOI Crossref

An epigenome-wide association study of total serum immunoglobulin E concentration.

Liang L, Willis-Owen SAG, Laprise C, ..., Moffatt MF, Cookson WOCM

Nature 520 (7549) 670-674 [2015-04-30; online 2015-02-18]

Affiliated researcher

PubMed DOI Crossref

Endostatin, Cathepsin S, and Cathepsin L, and Their Association with Inflammatory Markers and Mortality in Patients Undergoing Hemodialysis.

Carlsson AC, Carrero JJ, Stenvinkel P, ..., Larsson A, Ärnlöv J

Blood Purif. 39 (4) 259-265 [2015-04-29; online 2015-04-29]

Affiliated researcher

PubMed DOI Crossref

Single-Cell Characterization of in vitro Migration and Interaction Dynamics of T Cells Expanded with IL-2 and IL-7.

Tauriainen J, Gustafsson K, Göthlin M, ..., Uhlin M, Önfelt B

Front Immunol 6 (-) 196 [2015-04-28; online 2015-04-28]

Affiliated researcher

PubMed DOI Crossref

All-atom 3D structure prediction of transmembrane β-barrel proteins from sequences.

Hayat S, Sander C, Marks DS, Elofsson A

Proc. Natl. Acad. Sci. U.S.A. 112 (17) 5413-5418 [2015-04-28; online 2015-04-09]

Affiliated researcher

PubMed DOI Crossref

Frequency and distribution of Notch mutations in tumor cell lines.

Mutvei AP, Fredlund E, Lendahl U

BMC Cancer 15 (-) 311 [2015-04-25; online 2015-04-25]

Affiliated researcher

PubMed DOI Crossref

Membrane nanoclusters-tails of the unexpected.

Sezgin E, Davis SJ, Eggeling C

Cell 161 (3) 433-434 [2015-04-23; online 2015-04-25]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Genetically determined height and coronary artery disease.

Nelson CP, Hamby SE, Saleheen D, ..., Samani NJ, CARDIoGRAM+C4D Consortium

N. Engl. J. Med. 372 (17) 1608-1618 [2015-04-23; online 2015-04-08]

Affiliated researcher

PubMed DOI Crossref

Adaptive lipid packing and bioactivity in membrane domains.

Sezgin E, Gutmann T, Buhl T, ..., Levental I, Schwille P

PLoS ONE 10 (4) e0123930 [2015-04-23; online 2015-04-23]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Fast and sensitive total protein and Peptide assays for proteomic analysis.

Wiśniewski JR, Gaugaz FZ

Anal. Chem. 87 (8) 4110-4116 [2015-04-21; online 2015-04-09]

Affiliated researcher

PubMed DOI Crossref

Circulating carnosine dipeptidase 1 associates with weight loss and poor prognosis in gastrointestinal cancer.

Arner P, Henjes F, Schwenk JM, ..., Nilsson P, Rydén M

PLoS ONE 10 (4) e0123566 [2015-04-21; online 2015-04-21]

Affiliated researcher

PubMed DOI Crossref

What matters for lac repressor search in vivo--sliding, hopping, intersegment transfer, crowding on DNA or recognition?

Mahmutovic A, Berg OG, Elf J

Nucleic Acids Res. 43 (7) 3454-3464 [2015-04-20; online 2015-03-16]

Affiliated researcher

PubMed DOI Crossref

Solid-phase cloning for high-throughput assembly of single and multiple DNA parts.

Lundqvist M, Edfors F, Sivertsson Å, ..., Uhlén M, Rockberg J

Nucleic Acids Res. 43 (7) e49 [2015-04-20; online 2015-01-23]

Affiliated researcher Paul Hudson SciLifeLab Fellow

PubMed DOI Crossref

CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells.

Ratz M, Testa I, Hell SW, Jakobs S

Sci Rep 5 (1) 9592 [2015-04-20; online 2015-04-20]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Exploration of the arrest peptide sequence space reveals arrest-enhanced variants.

Cymer F, Hedman R, Ismail N, von Heijne G

J. Biol. Chem. 290 (16) 10208-10215 [2015-04-17; online 2015-02-24]

Affiliated researcher

PubMed DOI Crossref

Different distribution of histone modifications in genes with unidirectional and bidirectional transcription and a role of CTCF and cohesin in directing transcription.

Bornelöv S, Komorowski J, Wadelius C

BMC Genomics 16 (-) 300 [2015-04-15; online 2015-04-15]

Affiliated researcher

PubMed DOI Crossref

Extensive intra-phylotype diversity in lactobacilli and bifidobacteria from the honeybee gut.

Ellegaard KM, Tamarit D, Javelind E, ..., Andersson SG, Vásquez A

BMC Genomics 16 (-) 284 [2015-04-11; online 2015-04-11]

Affiliated researcher

PubMed DOI Crossref

AP-1-mediated chromatin looping regulates ZEB2 transcription: new insights into TNFα-induced epithelial-mesenchymal transition in triple-negative breast cancer.

Qiao Y, Shiue CN, Zhu J, ..., Zhao C, Dahlman-Wright K

Oncotarget 6 (10) 7804-7814 [2015-04-10; online 2015-03-13]

Affiliated researcher

PubMed DOI Crossref

Synthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase.

Chofor R, Sooriyaarachchi S, Risseeuw MD, ..., Mowbray SL, Van Calenbergh S

J. Med. Chem. 58 (7) 2988-3001 [2015-04-09; online 2015-03-31]

Affiliated researcher

PubMed DOI Crossref

The structure of the human mitochondrial ribosome

Amunts A, Brown A, Toots J, Scheres SHW, Ramakrishnan V

Science 348 (6230) 95-98 [2015-04-03; online 2015-04-02]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

An entity evolving into a community: defining the common ancestor and evolutionary trajectory of chronic lymphocytic leukemia stereotyped subset #4.

Sutton LA, Papadopoulos G, Hadzidimitriou A, ..., Tzovaras D, Stamatopoulos K

Mol. Med. 20 (-) 720-728 [2015-04-02; online 2015-04-02]

Affiliated researcher

PubMed DOI Crossref

Neighborhood deprivation and warfarin, aspirin and statin prescription - A cohort study of men and women treated for atrial fibrillation in Swedish primary care.

Carlsson AC, Wändell P, Gasevic D, Sundquist J, Sundquist K

Int. J. Cardiol. 187 (-) 547-552 [2015-04-01; online 2015-04-01]

Affiliated researcher

PubMed DOI Crossref

Behavioral cost & overdominance in Anopheles gambiae.

Diop MM, Moiroux N, Chandre F, ..., Labbé P, Pennetier C

PLoS ONE 10 (4) e0121755 [2015-04-01; online 2015-04-01]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

A prognosis based classification of undifferentiated uterine sarcomas: identification of mitotic index, hormone receptors and YWHAE-FAM22 translocation status as predictors of survival.

Gremel G, Liew M, Hamzei F, ..., Pontén F, Carlson JW

Int. J. Cancer 136 (7) 1608-1618 [2015-04-01; online 2014-08-27]

Affiliated researcher

PubMed DOI Crossref

UBE2D3 is a positive prognostic factor and is negatively correlated with hTERT expression in esophageal cancer.

Guan GG, Wang WB, Lei BX, ..., Zhou FX, Zhou YF

Oncol Lett 9 (4) 1567-1574 [2015-04-00; online 2015-02-03]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

Synthesis and biological evaluation of [¹¹C]AZ12504948; a novel tracer for imaging of glucokinase in pancreas and liver.

Jahan M, Johnström P, Nag S, ..., Halldin C, Eriksson O

Nucl. Med. Biol. 42 (4) 387-394 [2015-04-00; online 2014-12-06]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Synchrotron X-ray phase nano-tomography-based analysis of the lacunar-canalicular network morphology and its relation to the strains experienced by osteocytes in situ as predicted by case-specific finite element analysis.

Varga P, Hesse B, Langer M, ..., Peyrin F, Raum K

Biomech Model Mechanobiol 14 (2) 267-282 [2015-04-00; online 2014-07-11]

Affiliated researcher

PubMed DOI Crossref

Regulation of cerebral CYP2D alters tramadol metabolism in the brain: interactions of tramadol with propranolol and nicotine.

Wang Q, Han X, Li J, ..., Dong G, Yue J

Xenobiotica 45 (4) 335-344 [2015-04-00; online 2014-11-12]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

RIFINs are adhesins implicated in severe Plasmodium falciparum malaria.

Goel S, Palmkvist M, Moll K, ..., Nilsson I, Wahlgren M

Nat. Med. 21 (4) 314-317 [2015-04-00; online 2015-03-09]

Affiliated researcher

PubMed DOI Crossref

Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains.

Beck-García K, Beck-García E, Bohler S, ..., Alarcón B, Schamel WW

Biochim. Biophys. Acta 1853 (4) 802-809 [2015-04-00; online 2014-12-20]

Erdinc Sezgin SciLifeLab Fellow

PubMed DOI Crossref

Molecular histology of lung cancer: from targets to treatments.

Wood SL, Pernemalm M, Crosbie PA, Whetton AD

Cancer Treat. Rev. 41 (4) 361-375 [2015-04-00; online 2015-02-20]

Affiliated researcher

PubMed DOI Crossref

Microfluidic-based isolation of bacteria from whole blood for sepsis diagnostics.

Zelenin S, Hansson J, Ardabili S, ..., Brismar H, Russom A

Biotechnol. Lett. 37 (4) 825-830 [2015-04-00; online 2014-11-21]

Affiliated researcher

PubMed DOI Crossref

Matrix metalloproteinase-9 is essential for physiological Beta cell function and islet vascularization in adult mice.

Christoffersson G, Waldén T, Sandberg M, ..., Carlsson PO, Phillipson M

Am. J. Pathol. 185 (4) 1094-1103 [2015-04-00; online 2015-02-07]

Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

Lysophosphatidic acid receptor (LPAR) modulators: The current pharmacological toolbox.

Llona-Minguez S, Ghassemian A, Helleday T

Prog. Lipid Res. 58 (-) 51-75 [2015-04-00; online 2015-02-20]

Affiliated researcher

PubMed DOI Crossref

Implications of enterotoxigenic Escherichia coli genomics for vaccine development.

Sjöling Å, von Mentzer A, Svennerholm AM

Expert Rev Vaccines 14 (4) 551-560 [2015-04-00; online 2014-12-26]

Astrid von Mentzer DDLS Fellow

PubMed DOI Crossref

Immunohistochemistry-based prognostic biomarkers in NSCLC: novel findings on the road to clinical use?

Lindskog C, Edlund K, Mattsson JS, Micke P

Expert Rev. Mol. Diagn. 15 (4) 471-490 [2015-04-00; online 2015-01-19]

Affiliated researcher

PubMed DOI Crossref

High levels of soluble tumor necrosis factor receptors 1 and 2 and their association with mortality in patients undergoing hemodialysis.

Carlsson AC, Carrero JJ, Stenvinkel P, ..., Larsson A, Ärnlöv J

Cardiorenal Med 5 (2) 89-95 [2015-04-00; online 2015-01-30]

Affiliated researcher

PubMed DOI Crossref

GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb.

den Hoed M, Strawbridge RJ, Almgren P, ..., Melander O, Lind L

Atherosclerosis 239 (2) 304-310 [2015-04-00; online 2015-01-31]

Affiliated researcher

PubMed DOI Crossref

Functional anti-CD94/NKG2A and anti-CD94/NKG2C autoantibodies in patients with systemic lupus erythematosus.

Hagberg N, Theorell J, Hjorton K, ..., Bryceson YT, Rönnblom L

Arthritis & rheumatology (Hoboken, N.J.) 67 (4) 1000-1011 [2015-04-00; online 2014-12-17]

Affiliated researcher

PubMed DOI Crossref

Extreme recombination frequencies shape genome variation and evolution in the honeybee, Apis mellifera.

Wallberg A, Glémin S, Webster MT

PLoS Genet 11 (4) e1005189 [2015-04-00; online 2015-04-22]

Affiliated researcher

PubMed DOI Crossref

Evidence of streptococcal origin of acute non-necrotising cellulitis: a serological study.

Karppelin M, Siljander T, Haapala AM, ..., Vuopio J, Syrjänen J

Eur. J. Clin. Microbiol. Infect. Dis. 34 (4) 669-672 [2015-04-00; online 2014-11-18]

Affiliated researcher

PubMed DOI Crossref

Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells.

Bouris P, Skandalis SS, Piperigkou Z, ..., Theocharis AD, Karamanos NK

Matrix Biol. 43 (-) 42-60 [2015-04-00; online 2015-02-27]

Affiliated researcher

PubMed DOI Crossref

Duffy antigen receptor genetic variant and the association with Interleukin 8 levels.

Moreno Velásquez I, Kumar J, Björkbacka H, ..., de Faire U, Gigante B

Cytokine 72 (2) 178-184 [2015-04-00; online 2015-01-31]

Affiliated researcher

PubMed DOI Crossref

Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer's disease.

Ádori C, Glück L, Barde S, ..., Schulz S, Hökfelt T

Acta Neuropathol. 129 (4) 541-563 [2015-04-00; online 2015-02-13]

Affiliated researcher

PubMed DOI Crossref

Chimeric antigen receptor-engineered T cells for the treatment of metastatic prostate cancer.

Hillerdal V, Essand M

BioDrugs 29 (2) 75-89 [2015-04-00; online 2015-04-11]

Affiliated researcher

PubMed DOI Crossref

Calcium signaling in neocortical development.

Uhlén P, Fritz N, Smedler E, Malmersjö S, Kanatani S

Dev Neurobiol 75 (4) 360-368 [2015-04-00; online 2015-02-18]

Affiliated researcher

PubMed DOI Crossref

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study.

Hägg S, Fall T, Ploner A, ..., Ingelsson E, European Network for Genetic and Genomic Epidemiology Consortium

Int J Epidemiol 44 (2) 578-586 [2015-04-00; online 2015-05-27]

Affiliated researcher

PubMed DOI Crossref

Aberrant post-translational modifications compromise human myosin motor function in old age.

Li M, Ogilvie H, Ochala J, ..., Bergquist J, Larsson L

Aging Cell 14 (2) 228-235 [2015-04-00; online 2015-02-02]

Affiliated researcher

PubMed DOI Crossref

A missense change in the ATG4D gene links aberrant autophagy to a neurodegenerative vacuolar storage disease.

Kyöstilä K, Syrjä P, Jagannathan V, ..., Lohi H, Leeb T

PLoS Genet 11 (4) e1005169 [2015-04-00; online 2015-04-15]

Affiliated researcher

PubMed DOI Crossref

The code for directing proteins for translocation across ER membrane: SRP cotranslationally recognizes specific features of a signal sequence.

Nilsson I, Lara P, Hessa T, ..., von Heijne G, Karamyshev AL

J. Mol. Biol. 427 (6 Pt A) 1191-1201 [2015-03-27; online 2014-06-28]

Affiliated researcher

PubMed DOI Crossref

Rewired metabolism in drug-resistant leukemia cells: a metabolic switch hallmarked by reduced dependence on exogenous glutamine.

Stäubert C, Bhuiyan H, Lindahl A, ..., Lehtiö J, Nordström A

J. Biol. Chem. 290 (13) 8348-8359 [2015-03-27; online 2015-02-19]

Affiliated researcher

PubMed DOI Crossref

Dissecting antibodies with regards to linear and conformational epitopes.

Forsström B, Axnäs BB, Rockberg J, ..., Bohlin A, Uhlen M

PLoS ONE 10 (3) e0121673 [2015-03-27; online 2015-03-27]

Affiliated researcher

PubMed DOI Crossref

Catalytic stimulation by restrained active-site floppiness--the case of high density lipoprotein-bound serum paraoxonase-1.

Ben-David M, Sussman JL, Maxwell CI, ..., Kamerlin SCL, Tawfik DS

J. Mol. Biol. 427 (6 Pt B) 1359-1374 [2015-03-27; online 2015-01-30]

Affiliated researcher

PubMed DOI Crossref

Low RBM3 protein expression correlates with clinical stage, prognostic classification and increased risk of treatment failure in testicular non-seminomatous germ cell cancer.

Olofsson SE, Nodin B, Gaber A, ..., Jirström K, Jerkeman M

PLoS ONE 10 (3) e0121300 [2015-03-26; online 2015-03-26]

Affiliated researcher

PubMed DOI Crossref

Transducin duplicates in the zebrafish retina and pineal complex: differential specialisation after the teleost tetraploidisation.

Lagman D, Callado-Pérez A, Franzén IE, Larhammar D, Abalo XM

PLoS ONE 10 (3) e0121330 [2015-03-25; online 2015-03-25]

Affiliated researcher

PubMed DOI Crossref

Crystal structures of the kinase domain of the sulfate-activating complex in Mycobacterium tuberculosis.

Poyraz Ö, Brunner K, Lohkamp B, ..., Schnell R, Schneider G

PLoS ONE 10 (3) e0121494 [2015-03-25; online 2015-03-25]

Affiliated researcher

PubMed DOI Crossref

Coordinated international action to accelerate genome-to-phenome with FAANG, the Functional Annotation of Animal Genomes project.

Andersson L, Archibald AL, Bottema CD, ..., Zhou H, FAANG Consortium

Genome Biol. 16 (-) 57 [2015-03-25; online 2015-03-25]

Affiliated researcher

PubMed DOI Crossref

A validated liquid chromatography tandem mass spectrometry method for quantification of erlotinib, OSI-420 and didesmethyl erlotinib and semi-quantification of erlotinib metabolites in human plasma.

Svedberg A, Gréen H, Vikström A, Lundeberg J, Vikingsson S

J Pharm Biomed Anal 107 (-) 186-195 [2015-03-25; online 2014-12-25]

Affiliated researcher

PubMed DOI Crossref

Molecular docking screening using agonist-bound GPCR structures: probing the A2A adenosine receptor.

Rodríguez D, Gao ZG, Moss SM, Jacobson KA, Carlsson J

J Chem Inf Model 55 (3) 550-563 [2015-03-23; online 2015-02-13]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Proteomics profiling identify CAPS as a potential predictive marker of tamoxifen resistance in estrogen receptor positive breast cancer.

Johansson HJ, Sanchez BC, Forshed J, ..., Lehtiö J, Linderholm BK

Clin Proteomics 12 (1) 8 [2015-03-21; online 2015-03-21]

Affiliated researcher

PubMed DOI Crossref

The effects of exendin-4 treatment on graft failure: an animal study using a novel re-vascularized minimal human islet transplant model.

Sahraoui A, Winzell MS, Gorman T, ..., Foss A, Scholz H

PLoS ONE 10 (3) e0121204 [2015-03-20; online 2015-03-20]

Affiliated researcher

PubMed DOI Crossref

Chondroitin / dermatan sulfate modification enzymes in zebrafish development.

Habicher J, Haitina T, Eriksson I, ..., Ahlberg PE, Ledin J

PLoS ONE 10 (3) e0121957 [2015-03-20; online 2015-03-20]

Affiliated researcher

PubMed DOI Crossref

A Comprehensive, Automatically Updated Fungal ITS Sequence Dataset for Reference-Based Chimera Control in Environmental Sequencing Efforts.

Nilsson RH, Tedersoo L, Ryberg M, ..., Edgar RC, Abarenkov K

Microbes Environ 30 (2) 145-150 [2015-03-19; online 2015-03-19]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Local hopping mobile DNA implicated in pseudogene formation and reductive evolution in an obligate cyanobacteria-plant symbiosis.

Vigil-Stenman T, Larsson J, Nylander JA, Bergman B

BMC Genomics 16 (-) 193 [2015-03-17; online 2015-03-17]

Affiliated researcher

PubMed DOI Crossref

Resistant Microbial Cooccurrence Patterns Inferred by Network Topology

Peura S, Bertilsson S, Jones RI, Eiler A

Appl. Environ. Microbiol. 81 (6) 2090-2097 [2015-03-15; online 2015-01-09]

Affiliated researcher Sari Peura SciLifeLab Fellow

PubMed DOI Crossref

No redistribution of lung blood flow by inhaled nitric oxide in endotoxemic piglets pretreated with an endothelin receptor antagonist.

Trachsel S, Hambraeus-Jonzon K, Bergquist M, ..., Chen L, Hedenstierna G

J. Appl. Physiol. 118 (6) 768-775 [2015-03-15; online 2014-12-30]

Affiliated researcher

PubMed DOI Crossref

Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer.

Birgisson H, Edlund K, Wallin U, ..., Glimelius B, Sundström M

BMC Cancer 15 (-) 125 [2015-03-14; online 2015-03-14]

Affiliated researcher

PubMed DOI Crossref

The NDST gene family in zebrafish: role of NDST1B in pharyngeal arch formation.

Filipek-Górniok B, Carlsson P, Haitina T, ..., Ledin J, Kjellén L

PLoS ONE 10 (3) e0119040 [2015-03-13; online 2015-03-13]

Affiliated researcher

PubMed DOI Crossref

Mechanisms of integral membrane protein insertion and folding.

Cymer F, von Heijne G, White SH

J. Mol. Biol. 427 (5) 999-1022 [2015-03-13; online 2014-09-30]

Affiliated researcher

PubMed DOI Crossref

Computational and molecular tools for scalable rAAV-mediated genome editing.

Stoimenov I, Ali MA, Pandzic T, Sjöblom T

Nucleic Acids Res. 43 (5) e30 [2015-03-11; online 2014-12-08]

Affiliated researcher

PubMed DOI Crossref

How valence bond theory can help you understand your (bio)chemical reaction.

Shurki A, Derat E, Barrozo A, Kamerlin SC

Chem Soc Rev 44 (5) 1037-1052 [2015-03-07; online 2014-10-30]

Affiliated researcher

PubMed DOI Crossref

Bisphosphonate-modified biomaterials for drug delivery and bone tissue engineering.

Ossipov DA

Expert Opin Drug Deliv 12 (9) 1443-1458 [2015-03-05; online 2015-03-05]

Affiliated researcher

PubMed DOI Crossref

Binding of subdomains 1/2 of PfEMP1-DBL1α to heparan sulfate or heparin mediates Plasmodium falciparum rosetting.

Angeletti D, Sandalova T, Wahlgren M, Achour A

PLoS ONE 10 (3) e0118898 [2015-03-05; online 2015-03-05]

Affiliated researcher

PubMed DOI Crossref

Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.

Burguillos MA, Svensson M, Schulte T, ..., Joseph B, Deierborg T

Cell Reports - (-) - [2015-03-04; online 2015-03-04]

Affiliated researcher

PubMed DOI Crossref

Hybrid origins and the earliest stages of diploidization in the highly successful recent polyploid Capsella bursa-pastoris.

Douglas GM, Gos G, Steige KA, ..., Slotte T, Wright SI

Proc. Natl. Acad. Sci. U.S.A. 112 (9) 2806-2811 [2015-03-03; online 2015-02-17]

Affiliated researcher SciLifeLab Fellow Tanja Slotte

PubMed DOI Crossref

Proteomic profiling reveals autoimmune targets in sarcoidosis.

Häggmark A, Hamsten C, Wiklundh E, ..., Grunewald J, Nilsson P

Am. J. Respir. Crit. Care Med. 191 (5) 574-583 [2015-03-01; online 2015-01-22]

Affiliated researcher

PubMed DOI Crossref

The H1-receptor antagonist cetirizine ameliorates high-fat diet-induced glucose intolerance in male C57BL/6 mice, but not diabetes outcome in female non-obese diabetic (NOD) mice.

Anvari E, Wang X, Sandler S, Welsh N

Ups. J. Med. Sci. 120 (1) 40-46 [2015-03-00; online 2014-10-07]

Affiliated researcher

PubMed DOI Crossref

Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting.

Sutton LA, Ljungström V, Mansouri L, ..., Stamatopoulos K, Rosenquist R

Haematologica 100 (3) 370-376 [2015-03-00; online 2014-12-05]

Affiliated researcher

PubMed DOI Crossref

Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function.

Uematsu K, Heiman M, Zelenina M, ..., Nishi A, Greengard P

J. Neurochem. 132 (6) 677-686 [2015-03-00; online 2015-03-04]

Affiliated researcher

PubMed DOI Crossref

Preclinical characterization of acyl sulfonimidamides: potential carboxylic acid bioisosteres with tunable properties.

Borhade SR, Svensson R, Brandt P, ..., Arvidsson PI, Sandström A

ChemMedChem 10 (3) 455-460 [2015-03-00; online 2015-01-28]

Affiliated researcher

PubMed DOI Crossref

Plasma IL-5 concentration and subclinical carotid atherosclerosis.

Silveira A, McLeod O, Strawbridge RJ, ..., de Faire U, Hamsten A

Atherosclerosis 239 (1) 125-130 [2015-03-00; online 2014-12-23]

Affiliated researcher

PubMed DOI Crossref

Pharmacotherapy and mortality in atrial fibrillation--a cohort of men and women 75 years or older in Sweden.

Wändell PE, Carlsson AC, Sundquist J, ..., Bottai M, Sundquist K

Age Ageing 44 (2) 232-238 [2015-03-00; online 2014-10-16]

Affiliated researcher

PubMed DOI Crossref

Palmitate-induced impairments of β-cell function are linked with generation of specific ceramide species via acylation of sphingosine.

Manukyan L, Ubhayasekera SJ, Bergquist J, Sargsyan E, Bergsten P

Endocrinology 156 (3) 802-812 [2015-03-00; online 2014-12-23]

Affiliated researcher

PubMed DOI Crossref

PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6.

Oparina NY, Delgado-Vega AM, Martinez-Bueno M, ..., Alarcon-Riquelme ME, Kozyrev SV

Ann. Rheum. Dis. 74 (3) e14 [2015-03-00; online 2014-02-17]

Affiliated researcher

PubMed DOI Crossref

MuSK: a new target for lethal fetal akinesia deformation sequence (FADS).

Wilbe M, Ekvall S, Eurenius K, ..., Annerén G, Bondeson ML

J. Med. Genet. 52 (3) 195-202 [2015-03-00; online 2015-01-22]

Affiliated researcher

PubMed DOI Crossref

Integrated genome and transcriptome sequencing of the same cell.

Dey SS, Kester L, Spanjaard B, Bienko M, van Oudenaarden A

Nat. Biotechnol. 33 (3) 285-289 [2015-03-00; online 2015-01-19]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia--significance for activation of the kynurenine pathway.

Schwieler L, Larsson MK, Skogh E, ..., Erhardt S, Engberg G

J Psychiatry Neurosci 40 (2) 126-133 [2015-03-00; online 2014-12-03]

Affiliated researcher

PubMed DOI Crossref

Imaging of a clinically relevant stroke model: glucose hypermetabolism revisited.

Arnberg F, Grafström J, Lundberg J, ..., Stone-Elander S, Holmin S

Stroke 46 (3) 835-842 [2015-03-00; online 2015-02-05]

Affiliated researcher

PubMed DOI Crossref

FGF2 as a potential prognostic biomarker for proneural glioma patients.

Sooman L, Freyhult E, Jaiswal A, ..., Bergqvist M, Ekman S

Acta Oncol 54 (3) 385-394 [2015-03-00; online 2014-09-29]

Affiliated researcher

PubMed DOI Crossref

Differential transcriptional regulation of orthologous dps genes from two closely related heterocyst-forming cyanobacteria.

Li X, Sandh G, Nenninger A, Muro-Pastor AM, Stensjö K

FEMS Microbiol. Lett. 362 (6) - [2015-03-00; online 2015-02-05]

Affiliated researcher

PubMed DOI Crossref

Convergent evolution of the genomes of marine mammals.

Foote AD, Liu Y, Thomas GW, ..., Gilbert MT, Gibbs RA

Nat. Genet. 47 (3) 272-275 [2015-03-00; online 2015-01-26]

Affiliated researcher

PubMed DOI Crossref

A study of the clinical and radiological features in a cohort of 93 patients with a COL2A1 mutation causing spondyloepiphyseal dysplasia congenita or a related phenotype.

Terhal PA, Nievelstein RJ, Verver EJ, ..., Coucke P, Mortier GR

Am. J. Med. Genet. A 167A (3) 461-475 [2015-03-00; online 2015-01-21]

Affiliated researcher

PubMed DOI Crossref

A genomic duplication is associated with ectopic eomesodermin expression in the embryonic chicken comb and two duplex-comb phenotypes.

Dorshorst B, Harun-Or-Rashid M, Bagherpoor AJ, ..., Hallböök F, Andersson L

PLoS Genet 11 (3) e1004947 [2015-03-00; online 2015-03-19]

Affiliated researcher

PubMed DOI Crossref

An Integrated Bioinformatics Approach for Identifying Genetic Markers that Predict Cerebrospinal Fluid Biomarker p-tau181/Aβ1-42 Ratio in ApoE4-Negative Mild Cognitive Impairment Patients.

Sun Y, Bresell A, Rantalainen M, ..., Salter H, Alzheimer Disease Neuroimaging Initiative

J. Alzheimers Dis. 45 (4) 1061-1076 [2015-02-28; online 2015-02-28]

Affiliated researcher

PubMed DOI Crossref

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

Arner E, Daub CO, Vitting-Seerup K, ..., Carninci P, Hayashizaki Y

Science 347 (6225) 1010-1014 [2015-02-27; online 2015-02-12]

Affiliated researcher

PubMed DOI Crossref

Influence of antifreeze proteins on the ice/water interface.

Todde G, Hovmöller S, Laaksonen A

J Phys Chem B 119 (8) 3407-3413 [2015-02-26; online 2015-02-10]

Affiliated researcher

PubMed DOI Crossref

Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models.

Li Y, Drabsch Y, Pujuguet P, ..., Clément-Lacroix P, Ten Dijke P

Breast Cancer Res. 17 (-) 28 [2015-02-25; online 2015-02-25]

Affiliated researcher

PubMed DOI Crossref

Hydrophobic blocks facilitate lipid compatibility and translocon recognition of transmembrane protein sequences.

Stone TA, Schiller N, von Heijne G, Deber CM

Biochemistry 54 (7) 1465-1473 [2015-02-24; online 2015-02-12]

Affiliated researcher

PubMed DOI Crossref

Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.

Jendresen CB, Cui H, Zhang X, ..., Nilsson LN, Li JP

J. Biol. Chem. 290 (8) 5053-5064 [2015-02-20; online 2014-12-29]

Affiliated researcher

PubMed DOI Crossref

Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci.

Jäger R, Migliorini G, Henrion M, ..., Fletcher O, Houlston RS

Nat Commun 6 (-) 6178 [2015-02-19; online 2015-02-19]

Affiliated researcher

PubMed DOI Crossref

No difference in small bowel microbiota between patients with irritable bowel syndrome and healthy controls.

Dlugosz A, Winckler B, Lundin E, ..., Engstrand L, Lindberg G

Sci Rep 5 (-) 8508 [2015-02-17; online 2015-02-17]

Affiliated researcher

PubMed DOI Crossref

DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia.

Nordlund J, Bäcklin CL, Zachariadis V, ..., Forestier E, Syvänen AC

Clin Epigenetics 7 (-) 11 [2015-02-17; online 2015-02-17]

Affiliated researcher

PubMed DOI Crossref

Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci.

Rahmioglu N, Macgregor S, Drong AW, ..., Lindgren CM, Zondervan KT

Hum. Mol. Genet. 24 (4) 1185-1199 [2015-02-15; online 2014-10-08]

Affiliated researcher

PubMed

Dosimetry of [(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4 in rodents, pigs, non-human primates and human - repeated scanning in human is possible.

Selvaraju RK, Bulenga TN, Espes D, ..., Velikyan I, Eriksson O

American journal of nuclear medicine and molecular imaging 5 (3) 259-269 [2015-02-15; online 2015-02-15]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Synthesis and characterisation of lanthanide-hydroporphyrin dyads.

Xiong R, Andres J, Scheffler K, Borbas KE

Dalton Trans 44 (6) 2541-2553 [2015-02-14; online 2014-10-24]

Ruisheng Xiong SciLifeLab Fellow

PubMed DOI Crossref

New genetic loci link adipose and insulin biology to body fat distribution.

Shungin D, Winkler TW, Croteau-Chonka DC, ..., Lindgren CM, Mohlke KL

Nature 518 (7538) 187-196 [2015-02-12; online 2015-02-13]

Affiliated researcher

PubMed DOI Crossref

Genetic studies of body mass index yield new insights for obesity biology.

Locke AE, Kahali B, Berndt SI, ..., Loos RJF, Speliotes EK

Nature 518 (7538) 197-206 [2015-02-12; online 2015-02-13]

Affiliated researcher

PubMed DOI Crossref

Clonal distribution of BCR-ABL1 mutations and splice isoforms by single-molecule long-read RNA sequencing.

Cavelier L, Ameur A, Häggqvist S, ..., Olsson-Strömberg U, Hermanson M

BMC Cancer 15 (-) 45 [2015-02-12; online 2015-02-12]

Affiliated researcher

PubMed DOI Crossref

Deciphering solution scattering data with experimentally guided molecular dynamics simulations.

Björling A, Niebling S, Marcellini M, van der Spoel D, Westenhoff S

J Chem Theory Comput 11 (2) 780-787 [2015-02-10; online 2015-02-18]

Affiliated researcher

PubMed DOI Crossref

Methods applicable to membrane nanodomain studies?

Ashrafzadeh P, Parmryd I

Essays Biochem. 57 (-) 57-68 [2015-02-07; online 2015-02-07]

Affiliated researcher

PubMed DOI Crossref

A Bayesian decision support tool for efficient dose individualization of warfarin in adults and children.

Hamberg AK, Hellman J, Dahlberg J, Jonsson EN, Wadelius M

BMC Med Inform Decis Mak 15 (-) 7 [2015-02-07; online 2015-02-07]

Affiliated researcher

PubMed DOI Crossref

System-wide analysis of the transcriptional network of human myelomonocytic leukemia cells predicts attractor structure and phorbol-ester-induced differentiation and dedifferentiation transitions.

Sakata K, Ohyanagi H, Sato S, ..., Suzuki H, Saito T

Sci Rep 5 (-) 8283 [2015-02-06; online 2015-02-06]

Affiliated researcher

PubMed DOI Crossref

Synthesis of 4-quinolones via a carbonylative Sonogashira cross-coupling using molybdenum hexacarbonyl as a CO source.

Åkerbladh L, Nordeman P, Wejdemar M, Odell LR, Larhed M

J. Org. Chem. 80 (3) 1464-1471 [2015-02-06; online 2015-01-21]

Affiliated researcher

PubMed DOI Crossref

Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from human glioblastoma.

Babateen O, Jin Z, Bhandage A, ..., Smits A, Birnir B

Eur. J. Pharmacol. 748 (-) 101-107 [2015-02-05; online 2014-12-12]

Affiliated researcher

PubMed DOI Crossref

Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems.

Nestor CE, Ottaviano R, Reinhardt D, ..., Benson M, Meehan RR

Genome Biol. 16 (1) 11 [2015-02-04; online 2015-02-04]

Antonio Lentini DDLS Fellow

PubMed DOI Crossref

PON-P2: prediction method for fast and reliable identification of harmful variants.

Niroula A, Urolagin S, Vihinen M

PLoS ONE 10 (2) e0117380 [2015-02-03; online 2015-02-03]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Novel readout method for molecular diagnostic assays based on optical measurements of magnetic nanobead dynamics.

Donolato M, Antunes P, Bejhed RS, ..., Hansen MF, Vavassori P

Anal. Chem. 87 (3) 1622-1629 [2015-02-03; online 2015-01-09]

Affiliated researcher

PubMed DOI Crossref

Microbial community composition and diversity via 16S rRNA gene amplicons: evaluating the illumina platform.

Sinclair L, Osman OA, Bertilsson S, Eiler A

PLoS ONE 10 (2) e0116955 [2015-02-03; online 2015-02-03]

Affiliated researcher

PubMed DOI Crossref

Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling.

Ghaffari P, Mardinoglu A, Asplund A, ..., Uhlen M, Nielsen J

Sci Rep 5 (1) 8183 [2015-02-02; online 2015-02-02]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Flagellin as carrier and adjuvant in cocaine vaccine development.

Lockner JW, Eubanks LM, Choi JL, ..., Wilson IA, Janda KD

Mol. Pharm. 12 (2) 653-662 [2015-02-02; online 2015-01-07]

Daniel Globisch SciLifeLab Fellow

PubMed DOI Crossref

Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation.

Panas MD, Schulte T, Thaa B, ..., Achour A, McInerney GM

PLoS Pathog 11 (2) e1004659 [2015-02-00; online 2015-02-06]

Affiliated researcher

PubMed DOI Crossref

Splenic marginal-zone lymphoma: ontogeny and genetics.

Baliakas P, Strefford JC, Bikos V, ..., Stamatopoulos K, Oscier D

Leuk. Lymphoma 56 (2) 301-310 [2015-02-00; online 2014-08-19]

Affiliated researcher

PubMed DOI Crossref

Recurrent mutations refine prognosis in chronic lymphocytic leukemia.

Baliakas P, Hadzidimitriou A, Sutton LA, ..., Rosenquist R, European Research Initiative on CLL (ERIC)

Leukemia 29 (2) 329-336 [2015-02-00; online 2014-06-19]

Affiliated researcher

PubMed DOI Crossref

Proposal of Thorsellia kenyensis sp. nov. and Thorsellia kandunguensis sp. nov., isolated from larvae of Anopheles arabiensis, as members of the family Thorselliaceae fam. nov.

Kämpfer P, Glaeser SP, Nilsson LK, ..., Busse HJ, Terenius O

Int. J. Syst. Evol. Microbiol. 65 (Pt 2) 444-451 [2015-02-00; online 2014-11-10]

Affiliated researcher

PubMed DOI Crossref

Predicting venous thrombosis in women using a combination of genetic markers and clinical risk factors.

Bruzelius M, Bottai M, Sabater-Lleal M, ..., Hamsten A, Odeberg J

J. Thromb. Haemost. 13 (2) 219-227 [2015-02-00; online 2015-01-12]

Affiliated researcher

PubMed DOI Crossref

Interleukin-8 is associated with increased total mortality in women but not in men-findings from a community-based cohort of elderly.

Moreno Velásquez I, Ärnlöv J, Leander K, ..., Gigante B, Carlsson AC

Ann. Med. 47 (1) 28-33 [2015-02-00; online 2014-10-10]

Affiliated researcher

PubMed DOI Crossref

Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers.

Tonomura N, Elvers I, Thomas R, ..., Breen M, Lindblad-Toh K

PLoS Genet 11 (2) e1004922 [2015-02-00; online 2015-02-02]

Affiliated researcher

PubMed DOI Crossref

Genome and physiology of the ascomycete filamentous fungus Xeromyces bisporus, the most xerophilic organism isolated to date.

Leong SL, Lantz H, Pettersson OV, ..., Tellgren-Roth C, Schnürer J

Environ. Microbiol. 17 (2) 496-513 [2015-02-00; online 2014-10-07]

Affiliated researcher

PubMed DOI Crossref

Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy

Moreau A, Gosselin-Badaroudine P, Delemotte L, Klein ML, Chahine M

J Gen Physiol 145 (2) 93-106 [2015-02-00; online 2015-01-26]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Expression of human skin-specific genes defined by transcriptomics and antibody-based profiling.

Edqvist PH, Fagerberg L, Hallström BM, ..., Uhlén M, Pontén F

J. Histochem. Cytochem. 63 (2) 129-141 [2015-02-00; online 2014-11-19]

Affiliated researcher

PubMed DOI Crossref

Development and validation of method for TH588 and TH287, potent MTH1 inhibitors and new anti-cancer agents, for pharmacokinetic studies in mice plasma.

Saleh A, Gökturk C, Warpman-Berglund U, Helleday T, Granelli I

J Pharm Biomed Anal 104 (-) 1-11 [2015-02-00; online 2014-11-15]

Affiliated researcher

PubMed DOI Crossref

Detection of glyco-mucin profiles improves specificity of MUC16 and MUC1 biomarkers in ovarian serous tumours.

Ricardo S, Marcos-Silva L, Pereira D, ..., Lunet N, David L

Mol Oncol 9 (2) 503-512 [2015-02-00; online 2014-10-22]

Affiliated researcher

PubMed DOI Crossref

Clonal evolution in chronic lymphocytic leukemia: impact of subclonality on disease progression.

Sutton LA, Rosenquist R

Expert Rev Hematol 8 (1) 71-78 [2015-02-00; online 2014-10-27]

Affiliated researcher

PubMed DOI Crossref

Charge-driven dynamics of nascent-chain movement through the SecYEG translocon.

Ismail N, Hedman R, Lindén M, von Heijne G

Nat. Struct. Mol. Biol. 22 (2) 145-149 [2015-02-00; online 2015-01-05]

Affiliated researcher

PubMed DOI Crossref

Canalicular network morphology is the major determinant of the spatial distribution of mass density in human bone tissue: evidence by means of synchrotron radiation phase-contrast nano-CT.

Hesse B, Varga P, Langer M, ..., Peyrin F, Raum K

J. Bone Miner. Res. 30 (2) 346-356 [2015-02-00; online 2014-08-19]

Affiliated researcher

PubMed DOI Crossref

CTNND2-a candidate gene for reading problems and mild intellectual disability.

Hofmeister W, Nilsson D, Topa A, ..., Syk Lundberg E, Lindstrand A

J. Med. Genet. 52 (2) 111-122 [2015-02-00; online 2014-12-03]

Affiliated researcher

PubMed DOI Crossref

Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics

Amunts A, Fiedorczuk K, Truong TT, ..., Greenberg EP, Ramakrishnan V

Journal of Molecular Biology 427 (4) 753-755 [2015-02-00; online 2015-02-00]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

A general method for rapid determination of antibiotic susceptibility and species in bacterial infections.

Mezger A, Gullberg E, Göransson J, ..., Nilsson M, Andersson DI

J. Clin. Microbiol. 53 (2) 425-432 [2015-02-00; online 2014-11-19]

Affiliated researcher

PubMed DOI Crossref

Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle

Jordán-Pla A, Gupta I, de Miguel-Jiménez L, ..., Pelechano V, Pérez-Ortín JE

Nucleic Acids Res. 43 (2) 787-802 [2015-01-30; online 2014-12-29]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations.

Baliakas P, Agathangelidis A, Hadzidimitriou A, ..., Rosenquist R, Stamatopoulos K

Blood 125 (5) 856-859 [2015-01-29; online 2014-12-17]

Affiliated researcher

PubMed DOI Crossref

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.

Wessel J, Chu AY, Willems SM, ..., Scott RA, Goodarzi MO

Nat Commun 6 (-) 5897 [2015-01-29; online 2015-01-29]

Affiliated researcher

PubMed DOI Crossref

Regulation of human adenovirus alternative RNA splicing by the adenoviral L4-33K and L4-22K proteins.

Biasiotto R, Akusjärvi G

Int J Mol Sci 16 (2) 2893-2912 [2015-01-28; online 2015-01-28]

Affiliated researcher

PubMed DOI Crossref

Endonuclease specificity and sequence dependence of type IIS restriction enzymes.

Lundin S, Jemt A, Terje-Hegge F, ..., Lexow P, Lundeberg J

PLoS ONE 10 (1) e0117059 [2015-01-28; online 2015-01-28]

Affiliated researcher

PubMed DOI Crossref

TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor.

Sundar R, Gudey SK, Heldin CH, Landström M

Cell Cycle 14 (4) 554-565 [2015-01-27; online 2015-01-27]

Affiliated researcher

PubMed DOI Crossref

Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.

Mengelbier LH, Karlsson J, Lindgren D, ..., Mayrhofer M, Gisselsson D

Nat Commun 6 (-) 6125 [2015-01-27; online 2015-01-27]

Affiliated researcher

PubMed DOI Crossref

Scaling predictive modeling in drug development with cloud computing.

Moghadam BT, Alvarsson J, Holm M, ..., Carlsson L, Spjuth O

J Chem Inf Model 55 (1) 19-25 [2015-01-26; online 2015-01-08]

Affiliated researcher

PubMed DOI Crossref

Proteomics. Tissue-based map of the human proteome.

Uhlén M, Fagerberg L, Hallström BM, ..., Nielsen J, Pontén F

Science (New York, N.Y.) 347 (6220) 1260419 [2015-01-23; online 2015-01-24]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.

Westcott PM, Halliwill KD, To MD, ..., Adams DJ, Balmain A

Nature 517 (7535) 489-492 [2015-01-22; online 2014-11-02]

Affiliated researcher

PubMed DOI Crossref

Automatic GROMACS topology generation and comparisons of force fields for solvation free energy calculations.

Lundborg M, Lindahl E

J Phys Chem B 119 (3) 810-823 [2015-01-22; online 2014-11-07]

Affiliated researcher

PubMed DOI Crossref

Hydrogel patterning by diffusion through the matrix and subsequent light-triggered chemical immobilization.

Yi Z, Zhang Y, Kootala S, Hilborn J, Ossipov DA

ACS Appl Mater Interfaces 7 (2) 1194-1206 [2015-01-21; online 2015-01-09]

Affiliated researcher

PubMed DOI Crossref

Coupled diffusion in lipid bilayers upon close approach.

Pronk S, Lindahl E, Kasson PM

J. Am. Chem. Soc. 137 (2) 708-714 [2015-01-21; online 2015-01-06]

Affiliated researcher

PubMed DOI Crossref

Biological interpretation of genome-wide association studies using predicted gene functions.

Pers TH, Karjalainen JM, Chan Y, ..., Hirschhorn JN, Franke L

Nat Commun 6 (-) 5890 [2015-01-19; online 2015-01-19]

Affiliated researcher

PubMed DOI Crossref

Ancient mitochondrial DNA from the northern fringe of the Neolithic farming expansion in Europe sheds light on the dispersion process.

Malmström H, Linderholm A, Skoglund P, ..., Lidén K, Götherström A

Philos. Trans. R. Soc. Lond., B, Biol. Sci. 370 (1660) 20130373 [2015-01-19; online 2014-12-10]

Affiliated researcher

PubMed DOI Crossref

Variation in the human immune system is largely driven by non-heritable influences.

Brodin P, Jojic V, Gao T, ..., Maecker HT, Davis MM

Cell 160 (1-2) 37-47 [2015-01-15; online 2015-01-17]

Affiliated researcher

PubMed DOI Crossref

The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.

Altun M, Walter TS, Kramer HB, ..., Ren J, Kessler BM

PLoS ONE 10 (1) e0115344 [2015-01-15; online 2015-01-15]

Affiliated researcher

PubMed

Dosimetry of [(177)Lu]-DO3A-VS-Cys(40)-Exendin-4 - impact on the feasibility of insulinoma internal radiotherapy.

Velikyan I, Bulenga TN, Selvaraju R, ..., Rosenström U, Eriksson O

American journal of nuclear medicine and molecular imaging 5 (2) 109-126 [2015-01-15; online 2015-01-15]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

A proteomic approach to monitor the dynamic response of the female oviductal epithelial cell surface to male gametes.

Artemenko K, Horáková J, Steinberger B, ..., Bergquist J, Mayrhofer C

J Proteomics 113 (-) 1-14 [2015-01-15; online 2014-10-02]

Affiliated researcher

PubMed DOI Crossref

Dual channel RESOLFT nanoscopy by using fluorescent state kinetics.

Testa I, D'Este E, Urban NT, Balzarotti F, Hell SW

Nano Lett. 15 (1) 103-106 [2015-01-14; online 2014-12-02]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Pan-vertebrate comparative genomics unmasks retrovirus macroevolution.

Hayward A, Cornwallis CK, Jern P

Proc. Natl. Acad. Sci. U.S.A. 112 (2) 464-469 [2015-01-13; online 2014-12-22]

Affiliated researcher

PubMed DOI Crossref

Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease.

Hill RM, Kuijper S, Lindsey JC, ..., Chesler L, Clifford SC

Cancer Cell 27 (1) 72-84 [2015-01-12; online 2014-12-18]

Affiliated researcher

PubMed DOI Crossref

A high-throughput ChIP-Seq for large-scale chromatin studies.

Chabbert CD, Adjalley SH, Klaus B, ..., Pelechano V, Steinmetz LM

Mol Syst Biol 11 (1) 777 [2015-01-12; online 2015-01-12]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

The origin and evolution of maize in the Southwestern United States.

da Fonseca RR, Smith BD, Wales N, ..., Ross-Ibarra J, Gilbert MT

Nat Plants 1 (-) 14003 [2015-01-08; online 2015-01-08]

Affiliated researcher

PubMed DOI Crossref

Multiscale simulations of human telomeric G-quadruplex DNA.

Rebič M, Mocci F, Laaksonen A, Uličný J

J Phys Chem B 119 (1) 105-113 [2015-01-08; online 2014-12-17]

Affiliated researcher

PubMed DOI Crossref

DCDC2 mutations cause a renal-hepatic ciliopathy by disrupting Wnt signaling.

Schueler M, Braun DA, Chandrasekar G, ..., Kere J, Hildebrandt F

Am. J. Hum. Genet. 96 (1) 81-92 [2015-01-08; online 2014-12-31]

Affiliated researcher

PubMed DOI Crossref

TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells.

Fasching L, Kapopoulou A, Sachdeva R, ..., Trono D, Jakobsson J

Cell Reports 10 (1) 20-28 [2015-01-06; online 2014-12-24]

Affiliated researcher

PubMed DOI Crossref

Free-energy landscape of ion-channel voltage-sensor–domain activation

Delemotte L, Kasimova MA, Klein ML, Tarek M, Carnevale V

Proceedings of the National Academy of Sciences 112 (1) 124-129 [2015-01-06; online 2014-12-22]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

Mutagenesis. Smoking is associated with mosaic loss of chromosome Y.

Dumanski JP, Rasi C, Lönn M, ..., Ingelsson E, Forsberg LA

Science 347 (6217) 81-83 [2015-01-02; online 2014-12-04]

Affiliated researcher

PubMed DOI Crossref

A secretagogin locus of the mammalian hypothalamus controls stress hormone release.

Romanov RA, Alpár A, Zhang MD, ..., Hökfelt T, Harkany T

EMBO J. 34 (1) 36-54 [2015-01-02; online 2014-11-27]

Affiliated researcher

PubMed DOI Crossref

Characterization of peptide QRFP (26RFa) and its receptor from amphioxus, Branchiostoma floridae.

Xu B, Bergqvist CA, Sundström G, ..., Leprince J, Larhammar D

Gen. Comp. Endocrinol. 210 (-) 107-113 [2015-01-01; online 2014-10-25]

Affiliated researcher

PubMed DOI Crossref

VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation.

Huang H, Langenkamp E, Georganaki M, ..., Kreuger J, Dimberg A

FASEB J. 29 (1) 227-238 [2015-01-00; online 2014-10-31]

Affiliated researcher

PubMed DOI Crossref

The mutational landscape in pediatric acute lymphoblastic leukemia deciphered by whole genome sequencing.

Lindqvist CM, Nordlund J, Ekman D, ..., Syvänen AC, Berglund EC

Hum. Mutat. 36 (1) 118-128 [2015-01-00; online 2014-10-31]

Affiliated researcher

PubMed DOI Crossref

The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling.

Gremel G, Wanders A, Cedernaes J, ..., Uhlén M, Pontén F

J. Gastroenterol. 50 (1) 46-57 [2015-01-00; online 2014-05-01]

Affiliated researcher

PubMed DOI Crossref

The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition.

Tan EJ, Kahata K, Idås O, ..., Heldin CH, Moustakas A

Nucleic Acids Res. 43 (1) 162-178 [2015-01-00; online 2014-12-09]

Affiliated researcher

PubMed DOI Crossref

The Biobanking Analysis Resource Catalogue (BARCdb): a new research tool for the analysis of biobank samples.

Galli J, Oelrich J, Taussig MJ, ..., Ortega-Paino E, Landegren U

Nucleic Acids Res. 43 (Database issue) D1158-D1162 [2015-01-00; online 2014-10-21]

Affiliated researcher

DOI Crossref

Synthesis of Vinyl- and Aryl-Acyl Sulfonimidamides Through Pd-Catalyzed Carbonylation Using Mo(CO)6as ex situ CO Source

Wakchaure PB, Borhade SR, Sandström A, Arvidsson PI

Eur. J. Org. Chem. 2015 (1) 213-219 [2015-01-00; online 2014-11-19]

Affiliated researcher

PubMed DOI Crossref

Spatially resolved transcriptomics and beyond.

Crosetto N, Bienko M, van Oudenaarden A

Nat. Rev. Genet. 16 (1) 57-66 [2015-01-00; online 2014-12-02]

Affiliated researcher Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Reprogramming of Yersinia from virulent to persistent mode revealed by complex in vivo RNA-seq analysis.

Avican K, Fahlgren A, Huss M, ..., Dersch P, Fällman M

PLoS Pathog 11 (1) e1004600 [2015-01-00; online 2015-01-15]

Affiliated researcher

PubMed DOI Crossref

Lessons and implications from association studies and post-GWAS analyses of cervical cancer.

Chen D, Gyllensten U

Trends in Genetics 31 (1) 41-54 [2015-01-00; online 2014-11-18]

Affiliated researcher

PubMed DOI Crossref

InParanoid 8: orthology analysis between 273 proteomes, mostly eukaryotic.

Sonnhammer EL, Östlund G

Nucleic Acids Res. 43 (Database issue) D234-D239 [2015-01-00; online 2014-11-27]

Affiliated researcher

PubMed DOI Crossref

In vitro functional studies of rare CYP21A2 mutations and establishment of an activity gradient for nonclassic mutations improve phenotype predictions in congenital adrenal hyperplasia.

Barbaro M, Soardi FC, Östberg LJ, ..., Wedell A, Lajic S

Clin. Endocrinol. (Oxf) 82 (1) 37-44 [2015-01-00; online 2014-07-07]

Affiliated researcher

PubMed DOI Crossref

Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia.

Xochelli A, Agathangelidis A, Kavakiotis I, ..., Lefranc MP, Stamatopoulos K

Immunogenetics 67 (1) 61-66 [2015-01-00; online 2014-11-12]

Affiliated researcher

PubMed DOI Crossref

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.

Mahajan A, Sim X, Ng HJ, ..., Gloyn AL, T2D-GENES consortium and GoT2D consortium

PLoS Genet 11 (1) e1004876 [2015-01-00; online 2015-01-27]

Affiliated researcher

PubMed DOI Crossref

High plasma levels of heparin-binding epidermal growth factor are associated with a more stable plaque phenotype and reduced incidence of coronary events.

Rattik S, Wigren M, Björkbacka H, ..., Gonçalves I, Nilsson J

Arterioscler. Thromb. Vasc. Biol. 35 (1) 222-228 [2015-01-00; online 2014-10-30]

Affiliated researcher

PubMed DOI Crossref

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

Swerdlow DI, Preiss D, Kuchenbaecker KB, ..., Hingorani AD, Sattar N

The Lancet 385 (9965) 351-361 [2015-01-00; online 2015-01-00]

Affiliated researcher

PubMed DOI Crossref

Deregulated proliferation and differentiation in brain tumors.

Swartling FJ, Čančer M, Frantz A, Weishaupt H, Persson AI

Cell Tissue Res. 359 (1) 225-254 [2015-01-00; online 2014-11-23]

Affiliated researcher

PubMed DOI Crossref

Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolution.

Sutton LA, Rosenquist R

Haematologica 100 (1) 7-16 [2015-01-00; online 2015-01-02]

Affiliated researcher

PubMed DOI Crossref

Combining an amyloid-beta (Aβ) cleaving enzyme inhibitor with a γ-secretase modulator results in an additive reduction of Aβ production.

Strömberg K, Eketjäll S, Georgievska B, ..., Cowburn RF, Dabrowski M

FEBS J. 282 (1) 65-73 [2015-01-00; online 2014-11-07]

Affiliated researcher

PubMed DOI Crossref

Avoiding pitfalls in L1-regularised inference of gene networks.

Tjärnberg A, Nordling TE, Studham M, Nelander S, Sonnhammer EL

Mol Biosyst 11 (1) 287-296 [2015-01-00; online 2014-11-07]

Affiliated researcher

PubMed DOI Crossref

Assessment of HaloPlex amplification for sequence capture and massively parallel sequencing of arrhythmogenic right ventricular cardiomyopathy-associated genes.

Gréen A, Gréen H, Rehnberg M, ..., Gunnarsson C, Jonasson J

J Mol Diagn 17 (1) 31-42 [2015-01-00; online 2014-10-24]

Affiliated researcher

DOI Crossref

Applied Enantioselective Aminocatalysis: α-Heteroatom Functionalization Reactions on the Carbapenem (β-Lactam Antibiotic) Core

Cele ZED, Arvidsson PI, Kruger HG, Govender T, Naicker T

Eur. J. Org. Chem. 2015 (3) 638-646 [2015-01-00; online 2014-12-11]

Affiliated researcher

PubMed DOI Crossref

Allele variants of enterotoxigenic Escherichia coli heat-labile toxin are globally transmitted and associated with colonization factors.

Joffré E, von Mentzer A, Abd El Ghany M, ..., Svennerholm AM, Sjöling Å

J. Bacteriol. 197 (2) 392-403 [2015-01-00; online 2014-11-17]

Astrid von Mentzer DDLS Fellow

PubMed DOI Crossref

A Machine Learning Approach to Explain Drug Selectivity to Soluble and Membrane Protein Targets.

Freyhult E, Gustafsson MG, Strömbergsson H

Mol Inform 34 (1) 44-52 [2015-01-00; online 2015-01-08]

Affiliated researcher

DOI Crossref

Pd-catalyzed C–N coupling of vinylbromides and sulfonimidamides: a facile synthesis of N′-vinylsulfonimidamides

Nandi GC, Kota SR, Wakchaure PB, ..., Naicker T, Arvidsson PI

RSC Adv. 5 (76) 62084-62090 [2015-00-00; online 2015-00-00]

Affiliated researcher

DOI Crossref

On-chip ultrasonic sample preparation for cell based assays

Iranmanesh I, Ramachandraiah H, Russom A, Wiklund M

RSC Adv. 5 (91) 74304-74311 [2015-00-00; online 2015-00-00]

Affiliated researcher

PubMed DOI Crossref

Modulation of Bacterial Proliferation as a Survival Strategy

Heinrich K, Leslie DJ, Jonas K

- - (-) 127-171 [2015-00-00; online 2015-00-00]

Kristina Jonas SciLifeLab Fellow

DOI Crossref

Intriguing properties of unusual silicon nanocrystals

Manzetti S, Lu T, Behzadi H, ..., Thi Le HL, Vach H

RSC Adv. 5 (95) 78192-78208 [2015-00-00; online 2015-00-00]

Affiliated researcher

DOI Crossref

Functional porous membranes from amorphous linear dendritic polyester hybrids

Mongkhontreerat S, Walter MV, Cai Y, ..., Hult A, Malkoch M

Polym. Chem. 6 (13) 2390-2395 [2015-00-00; online 2015-00-00]

Affiliated researcher

DOI Crossref

Discovery of trace amine-associated receptor 1 ligands by molecular docking screening against a homology model

Lam VM, Rodríguez D, Zhang T, ..., Carlsson J, Salahpour A

Med. Chem. Commun. 6 (12) 2216-2223 [2015-00-00; online 2015-00-00]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

The kidney transcriptome and proteome defined by transcriptomics and antibody-based profiling.

Habuka M, Fagerberg L, Hallström BM, ..., Uhlén M, Odeberg J

PLoS ONE 9 (12) e116125 [2014-12-31; online 2014-12-31]

Affiliated researcher

PubMed DOI Crossref

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects.

Baumert J, Huang J, McKnight B, ..., Peters A, Smith NL

PLoS ONE 9 (12) e111156 [2014-12-31; online 2014-12-31]

Affiliated researcher

PubMed DOI Crossref

Genomic, proteomic, morphological, and phylogenetic analyses of vB_EcoP_SU10, a podoviridae phage with C3 morphology.

Khan Mirzaei M, Mirzaei MK, Eriksson H, ..., Haggård-Ljungquist E, Nilsson AS

PLoS ONE 9 (12) e116294 [2014-12-31; online 2014-12-31]

Affiliated researcher

PubMed DOI Crossref

Prehistoric genomes reveal the genetic foundation and cost of horse domestication.

Schubert M, Jónsson H, Chang D, ..., Shapiro B, Orlando L

Proc. Natl. Acad. Sci. U.S.A. 111 (52) E5661-E5669 [2014-12-30; online 2014-12-15]

Affiliated researcher

PubMed DOI Crossref

The human pancreas proteome defined by transcriptomics and antibody-based profiling.

Danielsson A, Pontén F, Fagerberg L, ..., Korsgren O, Lindskog C

PLoS ONE 9 (12) e115421 [2014-12-29; online 2014-12-29]

Affiliated researcher

PubMed DOI Crossref

The transcriptomic and proteomic landscapes of bone marrow and secondary lymphoid tissues.

Andersson S, Nilsson K, Fagerberg L, ..., Uhlen M, Asplund A

PLoS ONE 9 (12) e115911 [2014-12-26; online 2014-12-26]

Affiliated researcher

PubMed DOI Crossref

Mechanical stress downregulates MHC class I expression on human cancer cell membrane.

La Rocca R, Tallerico R, Talib Hassan A, ..., Di Fabrizio E, Carbone E

PLoS ONE 9 (12) e111758 [2014-12-26; online 2014-12-26]

Affiliated researcher

PubMed DOI Crossref

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence.

Genovese G, Kähler AK, Handsaker RE, ..., Hultman CM, McCarroll SA

N. Engl. J. Med. 371 (26) 2477-2487 [2014-12-25; online 2014-11-26]

Affiliated researcher

PubMed DOI Crossref

Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development.

Hsiao AS, Haslam RP, Michaelson LV, ..., Tanner JA, Chye ML

Biosci. Rep. 34 (6) e00165 [2014-12-23; online 2014-12-23]

Affiliated researcher

PubMed DOI Crossref

Enhanced normal-direction excitation and emission of dual-emitting quantum dots on a cascaded photonic crystal surface.

Chen ZH, Wang Y, Yang Y, ..., Wang Y, Yu Z

Nanoscale 6 (24) 14708-14715 [2014-12-21; online 2014-09-19]

Affiliated researcher

PubMed DOI Crossref

Palladium(II)-catalyzed desulfitative synthesis of aryl ketones from sodium arylsulfinates and nitriles: scope, limitations, and mechanistic studies.

Skillinghaug B, Sköld C, Rydfjord J, ..., Sjöberg PJ, Larhed M

J. Org. Chem. 79 (24) 12018-12032 [2014-12-19; online 2014-10-31]

Affiliated researcher

PubMed DOI Crossref

Germline methylation patterns determine the distribution of recombination events in the dog genome.

Berglund J, Quilez J, Arndt PF, Webster MT

Genome Biol Evol 7 (2) 522-530 [2014-12-19; online 2014-12-19]

Affiliated researcher

PubMed DOI Crossref

Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during Salmonella Typhimurium Colitis

Maier L, Diard M, Sellin ME, ..., Regoes RR, Hardt WD

PLoS Pathog 10 (12) e1004557 [2014-12-18; online 2014-12-18]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer.

Femel J, Huijbers EJ, Saupe F, ..., Hellman L, Olsson AK

Oncotarget 5 (23) 12418-12427 [2014-12-15; online 2014-11-02]

Affiliated researcher

PubMed DOI Crossref

The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair.

Henriksson S, Rassoolzadeh H, Hedström E, ..., Helleday T, Farnebo M

Genes Dev. 28 (24) 2726-2738 [2014-12-15; online 2014-12-17]

Affiliated researcher

PubMed DOI Crossref

The cerebrospinal fluid cytokine signature of multiple sclerosis: a homogenous response that does not conform to the Th1/Th2/Th17 convention.

Burman J, Svensson E, Fransson M, ..., Fagius J, Mangsbo SM

J. Neuroimmunol. 277 (1-2) 153-159 [2014-12-15; online 2014-10-18]

Affiliated researcher

PubMed DOI Crossref

A novel AP4M1 mutation in autosomal recessive cerebral palsy syndrome and clinical expansion of AP-4 deficiency.

Jameel M, Klar J, Tariq M, ..., Baig SM, Dahl N

BMC Med. Genet. 15 (-) 133 [2014-12-14; online 2014-12-14]

Affiliated researcher

PubMed DOI Crossref

Rapid pulsed whole genome sequencing for comprehensive acute diagnostics of inborn errors of metabolism.

Stranneheim H, Engvall M, Naess K, ..., von Döbeln U, Wedell A

BMC Genomics 15 (-) 1090 [2014-12-11; online 2014-12-11]

Affiliated researcher

PubMed DOI Crossref

Microfluidics-based in situ padlock/rolling circle amplification system for counting single DNA molecules in a cell.

Kuroda A, Ishigaki Y, Nilsson M, Sato K, Sato K

Anal Sci 30 (12) 1107-1112 [2014-12-11; online 2014-12-11]

Affiliated researcher

PubMed DOI Crossref

Diagnostics of primary immunodeficiency diseases: a sequencing capture approach.

Moens LN, Falk-Sörqvist E, Asplund AC, ..., Smith CI, Nilsson M

PLoS ONE 9 (12) e114901 [2014-12-11; online 2014-12-11]

Affiliated researcher

PubMed DOI Crossref

Genotypes do not confer risk for delinquency but rather alter susceptibility to positive and negative environmental factors: gene-environmentinteractions of BDNF Val66Met, 5-HTTLPR, and MAOA-uVNTR [corrected].

Nilsson KW, Comasco E, Hodgins S, Oreland L, Åslund C

Int J Neuropsychopharmacol 18 (5) - [2014-12-10; online 2014-12-10]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1.

Thakur N, Gudey SK, Marcusson A, ..., Heldin CH, Landström M

Cell Cycle 13 (15) 2400-2414 [2014-12-09; online 2014-12-09]

Affiliated researcher

PubMed DOI Crossref

Sensitive detection of aggregated prion protein via proximity ligation.

Hammond M, Wik L, Deslys JP, ..., Landegren U, Kamali-Moghaddam M

Prion 8 (3) 261-265 [2014-12-09; online 2014-12-09]

Affiliated researcher

PubMed DOI Crossref

Order Parameters and Algorithmic Approaches for Detection and Demarcation of Interfaces in Hydrate-Fluid and Ice-Fluid Systems.

Sæthre BS, Hoffmann AC, van der Spoel D

J Chem Theory Comput 10 (12) 5606-5615 [2014-12-09; online 2015-11-20]

Affiliated researcher

PubMed DOI Crossref

Inactivation of the budding yeast cohesin loader Scc2 alters gene expression both globally and in response to a single DNA double strand break.

Lindgren E, Hägg S, Giordano F, Björkegren J, Ström L

Cell Cycle 13 (23) 3645-3658 [2014-12-09; online 2014-12-09]

Affiliated researcher

PubMed DOI Crossref

Functional and molecular neuroimaging of menopause and hormone replacement therapy.

Comasco E, Frokjaer VG, Sundström-Poromaa I

Front Neurosci 8 (-) 388 [2014-12-08; online 2014-12-08]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Analysis of the early heterocyst Cys-proteome in the multicellular cyanobacterium Nostoc punctiforme reveals novel insights into the division of labor within diazotrophic filaments.

Sandh G, Ramström M, Stensjö K

BMC Genomics 15 (-) 1064 [2014-12-04; online 2014-12-04]

Affiliated researcher

PubMed DOI Crossref

Phenotypic effects of concomitant insensitive acetylcholinesterase (ace-1(R)) and knockdown resistance (kdr(R)) in Anopheles gambiae: a hindrance for insecticide resistance management for malaria vector control.

Assogba BS, Djogbénou LS, Saizonou J, ..., Weill M, Makoutodé M

Parasit Vectors 7 (-) 548 [2014-12-03; online 2014-12-03]

Pascal Milesi SciLifeLab Fellow

PubMed DOI Crossref

Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting - a technical approach.

Hillered L, Dahlin AP, Clausen F, ..., Enblad P, Lewén A

Front Neurol 5 (-) 245 [2014-12-03; online 2014-12-03]

Affiliated researcher

PubMed DOI Crossref

Shotgun metagenomics reveals a wide array of antibiotic resistance genes and mobile elements in a polluted lake in India.

Bengtsson-Palme J, Boulund F, Fick J, Kristiansson E, Larsson DG

Front Microbiol 5 (-) 648 [2014-12-02; online 2014-12-02]

DDLS Fellow Johan Bengtsson-Palme

PubMed DOI Crossref

Inhibition of tumor cell proliferation and motility by fibroblasts is both contact and soluble factor dependent.

Alkasalias T, Flaberg E, Kashuba V, ..., Klein G, Guven H

Proc. Natl. Acad. Sci. U.S.A. 111 (48) 17188-17193 [2014-12-02; online 2014-11-17]

Affiliated researcher

PubMed DOI Crossref

TGFβ receptor 1: an immune susceptibility gene in HPV-associated cancer.

Levovitz C, Chen D, Ivansson E, ..., Boffetta P, Sikora AG

Cancer Res. 74 (23) 6833-6844 [2014-12-01; online 2014-10-01]

Affiliated researcher

PubMed DOI Crossref

New insights into the evolution of vertebrate CRH (corticotropin-releasing hormone) and invertebrate DH44 (diuretic hormone 44) receptors in metazoans.

Cardoso JC, Félix RC, Bergqvist CA, Larhammar D

Gen. Comp. Endocrinol. 209 (-) 162-170 [2014-12-01; online 2014-09-16]

Affiliated researcher

PubMed DOI Crossref

Variability of the transporter gene complement in ammonia-oxidizing archaea.

Offre P, Kerou M, Spang A, Schleper C

Trends Microbiol. 22 (12) 665-675 [2014-12-00; online 2014-08-26]

Affiliated researcher

PubMed DOI Crossref

Understanding the structural and dynamic consequences of DNA epigenetic modifications: computational insights into cytosine methylation and hydroxymethylation.

Carvalho AT, Gouveia L, Kanna CR, ..., Platts JA, Kamerlin SC

Epigenetics 9 (12) 1604-1612 [2014-12-00; online 2015-01-28]

Affiliated researcher

PubMed DOI Crossref

Toxicogenomics directory of chemically exposed human hepatocytes

Grinberg M, Stöber RM, Edlund K, ..., Rahnenführer J, Hengstler JG

Arch Toxicol 88 (12) 2261-2287 [2014-12-00; online 2014-11-16]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Therapeutic vaccination targeting the tumour vasculature.

Olsson AK

Biochem. Soc. Trans. 42 (6) 1653-1657 [2014-12-00; online 2014-11-18]

Affiliated researcher

PubMed DOI Crossref

The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling.

Lindskog C, Fagerberg L, Hallström B, ..., Pontén F, Micke P

FASEB J. 28 (12) 5184-5196 [2014-12-00; online 2014-08-28]

Affiliated researcher

PubMed DOI Crossref

The glioblastoma vasculature as a target for cancer therapy.

Dimberg A

Biochem. Soc. Trans. 42 (6) 1647-1652 [2014-12-00; online 2014-11-18]

Affiliated researcher

PubMed DOI Crossref

The Salmonella Typhimurium effector protein SopE transiently localizes to the early SCV and contributes to intracellular replication

Vonaesch P, Sellin ME, Cardini S, ..., Barthel M, Hardt WD

Cell Microbiol 16 (12) 1723-1735 [2014-12-00; online 2014-08-26]

Mikael Sellin SciLifeLab Fellow

PubMed DOI Crossref

Superior long-term repopulating capacity of G-CSF+plerixafor-mobilized blood: implications for stem cell gene therapy by studies in the Hbb(th-3) mouse model.

Psatha N, Sgouramali E, Gkountis A, ..., Stamatoyannopoulos G, Yannaki E

Hum Gene Ther Methods 25 (6) 317-327 [2014-12-00; online 2014-10-22]

Affiliated researcher

PubMed DOI Crossref

Strategy to develop a MAO-A-resistant 5-hydroxy-L-[β-(11)C]tryptophan isotopologue based on deuterium kinetic isotope effects.

Eriksson J, Åberg O, Selvaraju RK, ..., Johansson L, Eriksson O

EJNMMI Res 4 (1) 62 [2014-12-00; online 2014-11-30]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

STED microscopy: increased resolution for medical research?

Blom H, Brismar H

J. Intern. Med. 276 (6) 560-578 [2014-12-00; online 2014-08-05]

Affiliated researcher

PubMed DOI Crossref

SATB1 is an independent prognostic factor in radically resected upper gastrointestinal tract adenocarcinoma.

Hedner C, Gaber A, Korkocic D, ..., Jirström K, Eberhard J

Virchows Arch. 465 (6) 649-659 [2014-12-00; online 2014-10-19]

Affiliated researcher

PubMed DOI Crossref

Predictive value of excision repair cross-complementation group 1 expression for platinum-based chemotherapy and survival in gastric cancer: a meta-analysis.

Yao A, Wang Y, Peng X, ..., Qi Y, Zhou F

J. Cancer Res. Clin. Oncol. 140 (12) 2107-2117 [2014-12-00; online 2014-07-04]

DDLS Fellow Qiaoli Wang

PubMed DOI Crossref

Pharmacogenetics, plasma concentrations, clinical signs and EEG during propofol treatment.

Khan MS, Zetterlund EL, Gréen H, ..., Persson H, Eintrei C

Basic Clin. Pharmacol. Toxicol. 115 (6) 565-570 [2014-12-00; online 2014-07-19]

Affiliated researcher

PubMed DOI Crossref

Marine sponge Cribrochalina vasculum compounds activate intrinsic apoptotic signaling and inhibit growth factor signaling cascades in non-small cell lung carcinoma.

Zovko A, Viktorsson K, Hååg P, ..., Carmeli S, Lewensohn R

Mol. Cancer Ther. 13 (12) 2941-2954 [2014-12-00; online 2014-10-15]

Affiliated researcher

PubMed DOI Crossref

MICA polymorphism: biology and importance in cancer.

Chen D, Gyllensten U

Carcinogenesis 35 (12) 2633-2642 [2014-12-00; online 2014-10-20]

Affiliated researcher

PubMed DOI Crossref

Large-scale metabolomic profiling identifies novel biomarkers for incident coronary heart disease.

Ganna A, Salihovic S, Sundström J, ..., Fall T, Ingelsson E

PLoS Genet 10 (12) e1004801 [2014-12-00; online 2014-12-11]

Affiliated researcher

PubMed DOI Crossref

Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides.

Borhade SR, Rosenström U, Sävmarker J, ..., Larhed M, Hallberg M

ChemistryOpen 3 (6) 256-263 [2014-12-00; online 2014-11-21]

Affiliated researcher

PubMed DOI Crossref

Impact of ABCB1 single nucleotide polymorphisms 1236C>T and 2677G>T on overall survival in FLT3 wild-type de novo AML patients with normal karyotype.

Jakobsen Falk I, Fyrberg A, Paul E, ..., Gréen H, Lotfi K

Br. J. Haematol. 167 (5) 671-680 [2014-12-00; online 2014-08-23]

Affiliated researcher

PubMed DOI Crossref

Identification of enterotoxigenic Escherichia coli (ETEC) clades with long-term global distribution.

von Mentzer A, Connor TR, Wieler LH, ..., Sjöling Å, Dougan G

Nat. Genet. 46 (12) 1321-1326 [2014-12-00; online 2014-11-10]

Astrid von Mentzer DDLS Fellow

PubMed DOI Crossref

Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease

Mardinoglu A, Agren R, Kampf C, ..., Uhlen M, Nielsen J

Nat Commun 5 (1) - [2014-12-00; online 2014-01-14]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Gender differences and time trends in incidence and prevalence of type 2 diabetes in Sweden--a model explaining the diabetes epidemic worldwide today?

Wändell PE, Carlsson AC

Diabetes Res. Clin. Pract. 106 (3) e90-e92 [2014-12-00; online 2014-10-02]

Affiliated researcher

PubMed DOI Crossref

GABAergic terminals are a source of galanin to modulate cholinergic neuron development in the neonatal forebrain.

Keimpema E, Zheng K, Barde SS, ..., Hökfelt T, Harkany T

Cereb. Cortex 24 (12) 3277-3288 [2014-12-00; online 2013-07-29]

Affiliated researcher

PubMed DOI Crossref

Evaluation of efficacy of a new MEK inhibitor, RO4987655, in human tumor xenografts by [(18)F] FDG-PET imaging combined with proteomic approaches.

Tegnebratt T, Ruge E, Bader S, ..., Tessier J, Stone-Elander S

EJNMMI Res 4 (1) 34 [2014-12-00; online 2014-09-09]

Affiliated researcher

PubMed DOI Crossref

Emotional and cognitive functional imaging of estrogen and progesterone effects in the female human brain: a systematic review.

Toffoletto S, Lanzenberger R, Gingnell M, Sundström-Poromaa I, Comasco E

Psychoneuroendocrinology 50 (-) 28-52 [2014-12-00; online 2014-08-13]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Efficient application of next-generation sequencing for the diagnosis of rare genetic syndromes.

Madrigal I, Alvarez-Mora MI, Karlberg O, ..., Syvänen AC, Milà M

J. Clin. Pathol. 67 (12) 1099-1103 [2014-12-00; online 2014-09-30]

Affiliated researcher

PubMed DOI Crossref

Dual labeled Ag@SiO₂ core-shell nanoparticle based optical immunosensor for sensitive detection of E. coli.

Krishnan S, Chinnasamy T, Veerappan S, Senthilkumar K, Kannaiyan D

Mater Sci Eng C Mater Biol Appl 45 (-) 337-342 [2014-12-00; online 2014-09-16]

Affiliated researcher

PubMed DOI Crossref

Differences in anthropometric measures in immigrants and Swedish-born individuals: results from two community-based cohort studies.

Carlsson AC, Wändell P, Riserus U, ..., Hellénius ML, de Faire U

Prev Med 69 (-) 151-156 [2014-12-00; online 2014-10-02]

Affiliated researcher

PubMed DOI Crossref

Comparative single-cell genomics reveals potential ecological niches for the freshwater acI Actinobacteria lineage.

Ghylin TW, Garcia SL, Moya F, ..., Bertilsson S, McMahon KD

ISME J 8 (12) 2503-2516 [2014-12-00; online 2014-08-05]

Affiliated researcher Sarahi Garcia SciLifeLab Fellow

PubMed DOI Crossref

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity.

Scott RA, Fall T, Pasko D, ..., Langenberg C, Wareham NJ

Diabetes 63 (12) 4378-4387 [2014-12-00; online 2014-06-19]

Affiliated researcher

DOI Crossref

Classification aided domain reduction for high dimensional optimization

Singh P, Ferranti F, Deschrijver D, Couckuyt I, Dhaene T

- - (-) - [2014-12-00; online 2014-12-00]

Prashant Singh SciLifeLab Fellow

PubMed DOI Crossref

A splice variant of the human phosphohistidine phosphatase 1 (PHPT1) is degraded by the proteasome.

Inturi R, Wäneskog M, Vlachakis D, ..., Punga T, Bjerling P

Int. J. Biochem. Cell Biol. 57 (-) 69-75 [2014-12-00; online 2014-10-14]

Affiliated researcher

PubMed DOI Crossref

PyTMs: a useful PyMOL plugin for modeling common post-translational modifications.

Warnecke A, Sandalova T, Achour A, Harris RA

BMC Bioinformatics 15 (-) 370 [2014-11-28; online 2014-11-28]

Affiliated researcher

PubMed DOI Crossref

Antibiotics in fetal and early life and subsequent childhood asthma: nationwide population based study with sibling analysis.

Örtqvist AK, Lundholm C, Kieler H, ..., Ye W, Almqvist C

BMJ 349 (-) g6979 [2014-11-28; online 2014-11-28]

Affiliated researcher

PubMed DOI Crossref

Community-driven development for computational biology at Sprints, Hackathons and Codefests.

Möller S, Afgan E, Banck M, ..., Katayama T, Chapman BA

BMC Bioinformatics 15 Suppl 14 (-) S7 [2014-11-27; online 2014-11-27]

Affiliated researcher

PubMed DOI Crossref

Induced ice melting by the snow flea antifreeze protein from molecular dynamics simulations.

Todde G, Whitman C, Hovmöller S, Laaksonen A

J Phys Chem B 118 (47) 13527-13534 [2014-11-26; online 2014-11-12]

Affiliated researcher

PubMed DOI Crossref

Insights into the Role of Asp79(2.50) in β2 Adrenergic Receptor Activation from Molecular Dynamics Simulations

Ranganathan A, Dror RO, Carlsson J

Biochemistry 53 (46) 7283-7296 [2014-11-25; online 2014-11-12]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Benchmarking study of parameter variation when using signature fingerprints together with support vector machines.

Alvarsson J, Eklund M, Andersson C, ..., Spjuth O, Wikberg JE

J Chem Inf Model 54 (11) 3211-3217 [2014-11-24; online 2014-10-28]

Affiliated researcher

PubMed DOI Crossref

1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer.

Mayrhofer M, Kultima HG, Birgisson H, ..., Glimelius B, Isaksson A

BMC Cancer 14 (-) 872 [2014-11-24; online 2014-11-24]

Affiliated researcher

PubMed DOI Crossref

The Eph tyrosine kinase receptors EphB2 and EphA2 are novel proteolytic substrates of tissue factor/coagulation factor VIIa.

Eriksson O, Ramström M, Hörnaeus K, ..., Mokhtari D, Siegbahn A

J. Biol. Chem. 289 (47) 32379-32391 [2014-11-21; online 2014-10-03]

Affiliated researcher

DOI Crossref

Safe Palladium-Catalyzed Cross-Couplings with Microwave Heating Using Continuous-Flow Silicon Carbide Reactors

Konda V, Rydfjord J, Sävmarker J, Larhed M

Org. Process Res. Dev. 18 (11) 1413-1418 [2014-11-21; online 2014-08-05]

Affiliated researcher

DOI Crossref

Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors

Engen K, Sävmarker J, Rosenström U, ..., Jenmalm-Jensen A, Larhed M

Org. Process Res. Dev. 18 (11) 1582-1588 [2014-11-21; online 2014-10-16]

Affiliated researcher

PubMed DOI Crossref

Constitutive activation of the ERK pathway in melanoma and skin melanocytes in Grey horses.

Jiang L, Campagne C, Sundström E, ..., Andersson L, Golovko A

BMC Cancer 14 (-) 857 [2014-11-21; online 2014-11-21]

Affiliated researcher

PubMed DOI Crossref

Scanning STED-FCS reveals spatiotemporal heterogeneity of lipid interaction in the plasma membrane of living cells.

Honigmann A, Mueller V, Ta H, ..., Hell SW, Eggeling C

Nat Commun 5 (-) 5412 [2014-11-20; online 2014-11-20]

Erdinc Sezgin SciLifeLab Fellow

DOI Crossref

Mild Microwave-Assisted Synthesis of Dipyrromethanes and Their Analogues

Borbas K, Xiong R

Synlett 26 (04) 484-488 [2014-11-18; online 2014-11-18]

Ruisheng Xiong SciLifeLab Fellow

PubMed DOI Crossref

Single-cell transcriptomics for microbial eukaryotes.

Kolisko M, Boscaro V, Burki F, Lynn DH, Keeling PJ

Curr. Biol. 24 (22) R1081-R1082 [2014-11-17; online 2014-11-17]

Fabien Burki SciLifeLab Fellow

PubMed DOI Crossref

Reprogramming during epithelial to mesenchymal transition under the control of TGFβ.

Tan EJ, Olsson AK, Moustakas A

Cell Adh Migr 9 (3) 233-246 [2014-11-17; online 2014-11-17]

Affiliated researcher

PubMed DOI Crossref

Pathway analysis of cervical cancer genome-wide association study highlights the MHC region and pathways involved in response to infection.

Chen D, Enroth S, Ivansson E, Gyllensten U

Hum. Mol. Genet. 23 (22) 6047-6060 [2014-11-15; online 2014-06-16]

Affiliated researcher

PubMed DOI Crossref

Reduced expression of the polymeric immunoglobulin receptor in pancreatic and periampullary adenocarcinoma signifies tumour progression and poor prognosis.

Fristedt R, Elebro J, Gaber A, ..., Eberhard J, Jirström K

PLoS ONE 9 (11) e112728 [2014-11-14; online 2014-11-14]

Affiliated researcher

PubMed DOI Crossref

Endostatin level is associated with kidney injury in the elderly: findings from two community-based cohorts.

Ruge T, Carlsson AC, Larsson TE, ..., Lind L, Ärnlöv J

Am. J. Nephrol. 40 (5) 417-424 [2014-11-14; online 2014-11-14]

Affiliated researcher

PubMed DOI Crossref

Structure of the large ribosomal subunit from human mitochondria

Brown A, Amunts A, Bai Xc, ..., Scheres SHW, Ramakrishnan V

Science 346 (6210) 718-722 [2014-11-07; online 2014-10-02]

Alexey Amunts SciLifeLab Fellow

PubMed DOI Crossref

Defining the Human Adipose Tissue Proteome To Reveal Metabolic Alterations in Obesity

Mardinoglu A, Kampf C, Asplund A, ..., Uhlen M, Nielsen J

J. Proteome Res. 13 (11) 5106-5119 [2014-11-07; online 2014-09-25]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Analysis of autoantibody profiles in osteoarthritis using comprehensive protein array concepts.

Henjes F, Lourido L, Ruiz-Romero C, ..., Nilsson P, Fuentes M

J. Proteome Res. 13 (11) 5218-5229 [2014-11-07; online 2014-10-09]

Affiliated researcher

PubMed DOI Crossref

Affinity proteomic profiling of plasma, cerebrospinal fluid, and brain tissue within multiple sclerosis.

Byström S, Ayoglu B, Häggmark A, ..., Nilsson P, Schwenk JM

J. Proteome Res. 13 (11) 4607-4619 [2014-11-07; online 2014-10-01]

Affiliated researcher

PubMed DOI Crossref

Quantifying colocalization: thresholding, void voxels and the H(coef).

Adler J, Parmryd I

PLoS ONE 9 (11) e111983 [2014-11-06; online 2014-11-06]

Affiliated researcher

PubMed DOI Crossref

Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1

Schmied WH, Elsässer SJ, Uttamapinant C, Chin JW

J. Am. Chem. Soc. 136 (44) 15577-15583 [2014-11-05; online 2014-10-28]

SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Detection of rotavirus using padlock probes and rolling circle amplification.

Mezger A, Öhrmalm C, Herthnek D, Blomberg J, Nilsson M

PLoS ONE 9 (11) e111874 [2014-11-04; online 2014-11-04]

Affiliated researcher

PubMed DOI Crossref

Gallium-68-labeled affibody molecule for PET imaging of PDGFRβ expression in vivo.

Strand J, Varasteh Z, Eriksson O, ..., Orlova A, Tolmachev V

Mol. Pharm. 11 (11) 3957-3964 [2014-11-03; online 2014-07-23]

Olof Eriksson SciLifeLab Fellow

PubMed DOI Crossref

Study of protein and RNA in dendritic spines using multi-isotope imaging mass spectrometry (MIMS).

Brismar H, Aperia A, Westin L, ..., Poczatek C, Lechene C

Surf Interface Anal 46 (Suppl 1) 158-160 [2014-11-01; online 2015-09-18]

Affiliated researcher

PubMed DOI Crossref

Tracing the evolution of FERM domain of Kindlins.

Ali RH, Khan AA

Mol. Phylogenet. Evol. 80 (-) 193-204 [2014-11-00; online 2014-08-20]

Affiliated researcher

PubMed DOI Crossref

The association between glomerular filtration rate and left ventricular function in two independent community-based cohorts of elderly.

Nerpin E, Ingelsson E, Risérus U, ..., Lars L, Ärnlöv J

Nephrol. Dial. Transplant. 29 (11) 2069-2074 [2014-11-00; online 2014-06-10]

Affiliated researcher

PubMed DOI Crossref

Systemic lupus erythematosus prevalence in Sweden in 2010: what do national registers say?

Simard JF, Sjöwall C, Rönnblom L, Jönsen A, Svenungsson E

Arthritis Care Res (Hoboken) 66 (11) 1710-1717 [2014-11-00; online 2014-04-24]

Affiliated researcher

PubMed DOI Crossref

Soluble tumor necrosis factor receptor 1 (sTNFR1) is associated with increased total mortality due to cancer and cardiovascular causes - findings from two community based cohorts of elderly.

Carlsson AC, Juhlin CC, Larsson TE, ..., Lind L, Arnlöv J

Atherosclerosis 237 (1) 236-242 [2014-11-00; online 2014-09-16]

Affiliated researcher

PubMed DOI Crossref

Silenced B-cell receptor response to autoantigen in a poor-prognostic subset of chronic lymphocytic leukemia.

Bergh AC, Evaldsson C, Pedersen LB, ..., Rosenquist R, Rosén A

Haematologica 99 (11) 1722-1730 [2014-11-00; online 2014-08-01]

Affiliated researcher

DOI Crossref

Polymeric Smart Coating Strategy for Titanium Implants

Berts I, Ossipov D, Fragneto G, Frisk A, Rennie AR

Adv. Eng. Mater. 16 (11) 1340-1350 [2014-11-00; online 2014-04-01]

Affiliated researcher

PubMed DOI Crossref

Parallel barcoding of antibodies for DNA-assisted proteomics.

Dezfouli M, Vickovic S, Iglesias MJ, Schwenk JM, Ahmadian A

Proteomics 14 (21-22) 2432-2436 [2014-11-00; online 2014-09-30]

Affiliated researcher Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

Integration of genome-wide of Stat3 binding and epigenetic modification mapping with transcriptome reveals novel Stat3 target genes in glioma cells.

Kruczyk M, Przanowski P, Dabrowski M, ..., Kaminska B, Komorowski J

Biochim. Biophys. Acta 1839 (11) 1341-1350 [2014-11-00; online 2014-08-08]

Affiliated researcher

PubMed DOI Crossref

Influence of persistent organic pollutants on oxidative stress in population-based samples.

Kumar J, Monica Lind P, Salihovic S, ..., Lind L, Ingelsson E

Chemosphere 114 (-) 303-309 [2014-11-00; online 2014-06-02]

Affiliated researcher

PubMed DOI Crossref

Improved contact predictions using the recognition of protein like contact patterns.

Skwark MJ, Raimondi D, Michel M, Elofsson A

PLoS Comput Biol 10 (11) e1003889 [2014-11-00; online 2014-11-06]

Affiliated researcher

PubMed DOI Crossref

High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA–tRNA interface

Schmitt BM, Rudolph KLM, Karagianni P, ..., Marioni JC, Kutter C

Genome Res. 24 (11) 1797-1807 [2014-11-00; online 2014-08-13]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Heparan sulfate in the regulation of neural differentiation and glioma development.

Xiong A, Kundu S, Forsberg-Nilsson K

FEBS J. 281 (22) 4993-5008 [2014-11-00; online 2014-11-06]

Affiliated researcher

PubMed DOI Crossref

Fat mass and obesity-associated gene (FTO) is linked to higher plasma levels of the hunger hormone ghrelin and lower serum levels of the satiety hormone leptin in older adults.

Benedict C, Axelsson T, Söderberg S, ..., Lind L, Schiöth HB

Diabetes 63 (11) 3955-3959 [2014-11-00; online 2014-06-04]

Affiliated researcher

PubMed DOI Crossref

Evolution reveals a glutathione-dependent mechanism of 3-hydroxypropionic acid tolerance.

Kildegaard KR, Hallström BM, Blicher TH, ..., Nielsen J, Borodina I

Metab. Eng. 26 (-) 57-66 [2014-11-00; online 2014-09-28]

Affiliated researcher

PubMed DOI Crossref

Defining the role of common variation in the genomic and biological architecture of adult human height.

Wood AR, Esko T, Yang J, ..., Hirschhorn JN, Frayling TM

Nat. Genet. 46 (11) 1173-1186 [2014-11-00; online 2014-10-05]

Affiliated researcher

PubMed DOI Crossref

Defining the human gallbladder proteome by transcriptomics and affinity proteomics

Kampf C, Mardinoglu A, Fagerberg L, ..., Pontén F, Uhlen M

Proteomics 14 (21-22) 2498-2507 [2014-11-00; online 2014-10-09]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study.

Baliakas P, Hadzidimitriou A, Sutton LA, ..., Ghia P, Stamatopoulos K

Lancet Haematol 1 (2) e74-e84 [2014-11-00; online 2014-11-03]

Affiliated researcher

PubMed DOI Crossref

Challenges in computational studies of enzyme structure, function and dynamics.

Carvalho AT, Barrozo A, Doron D, ..., Major DT, Kamerlin SC

J. Mol. Graph. Model. 54 (-) 62-79 [2014-11-00; online 2014-09-28]

Affiliated researcher

PubMed DOI Crossref

Binning metagenomic contigs by coverage and composition.

Alneberg J, Bjarnason BS, de Bruijn I, ..., Andersson AF, Quince C

Nat. Methods 11 (11) 1144-1146 [2014-11-00; online 2014-09-14]

Affiliated researcher

PubMed DOI Crossref

Abolished InsP3R2 function inhibits sweat secretion in both humans and mice.

Klar J, Hisatsune C, Baig SM, ..., Mikoshiba K, Dahl N

J. Clin. Invest. 124 (11) 4773-4780 [2014-11-00; online 2014-10-20]

Affiliated researcher

PubMed DOI Crossref

Haplotype-tag single nucleotide polymorphism analysis of the vesicular glutamate transporter (VGLUT) genes in severely alcoholic women.

Comasco E, Hallman J, Wallén-Mackenzie A

Psychiatry Res 219 (2) 403-405 [2014-10-30; online 2014-06-06]

Erika Comasco SciLifeLab Fellow

PubMed DOI Crossref

Oncogenic signaling is dominant to cell of origin and dictates astrocytic or oligodendroglial tumor development from oligodendrocyte precursor cells.

Lindberg N, Jiang Y, Xie Y, ..., Holland EC, Uhrbom L

J. Neurosci. 34 (44) 14644-14651 [2014-10-29; online 2014-10-31]

Affiliated researcher

PubMed DOI Crossref

Designing a multimer allergen for diagnosis and immunotherapy of dog allergic patients.

Nilsson OB, Neimert-Andersson T, Bronge M, ..., van Hage M, Grönlund H

PLoS ONE 9 (10) e111041 [2014-10-29; online 2014-10-29]

Affiliated researcher

PubMed DOI Crossref

Ligand-based target prediction with signature fingerprints.

Alvarsson J, Eklund M, Engkvist O, ..., Wikberg JE, Noeske T

J Chem Inf Model 54 (10) 2647-2653 [2014-10-27; online 2014-10-03]

Affiliated researcher

PubMed DOI Crossref

Unexpected multiplicity of QRFP receptors in early vertebrate evolution.

Larhammar D, Xu B, Bergqvist CA

Front Neurosci 8 (-) 337 [2014-10-24; online 2014-10-24]

Affiliated researcher

PubMed DOI Crossref

Structure and mechanism of Zn2+-transporting P-type ATPases.

Wang K, Sitsel O, Meloni G, ..., Nissen P, Gourdon P

Nature 514 (7523) 518-522 [2014-10-23; online 2014-08-17]

Affiliated researcher

PubMed DOI Crossref

Genetic variation reveals large-scale population expansion and migration during the expansion of Bantu-speaking peoples.

Li S, Schlebusch C, Jakobsson M

Proc. Biol. Sci. 281 (1793) - [2014-10-22; online 2014-09-10]

Affiliated researcher

PubMed DOI Crossref

DCDC2 polymorphism is associated with left temporoparietal gray and white matter structures during development.

Darki F, Peyrard-Janvid M, Matsson H, Kere J, Klingberg T

J. Neurosci. 34 (43) 14455-14462 [2014-10-22; online 2014-10-24]

Affiliated researcher

PubMed DOI Crossref

Prognostic and treatment predictive significance of SATB1 and SATB2 expression in pancreatic and periampullary adenocarcinoma.

Elebro J, Heby M, Gaber A, ..., Jirström K, Eberhard J

J Transl Med 12 (-) 289 [2014-10-17; online 2014-10-17]

Affiliated researcher

PubMed DOI Crossref

Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs.

Adoue V, Schiavi A, Light N, ..., Syvänen AC, Pastinen T

Mol Syst Biol 10 (-) 754 [2014-10-16; online 2014-10-16]

Affiliated researcher

PubMed DOI Crossref

Role of dietary fats in modulating cardiometabolic risk during moderate weight gain: a randomized double-blind overfeeding trial (LIPOGAIN study).

Iggman D, Rosqvist F, Larsson A, ..., Rudling M, Risérus U

J Am Heart Assoc 3 (5) e001095 [2014-10-15; online 2014-10-15]

Affiliated researcher

PubMed DOI Crossref

A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival.

Baecklund F, Foo JN, Bracci P, ..., Skibola CF, Smedby KE

BMC Med. Genet. 15 (-) 113 [2014-10-08; online 2014-10-08]

Affiliated researcher

PubMed DOI Crossref

Prevalence, incidence, mortality and co-morbidities amongst human immunodeficiency virus (HIV) patients in Stockholm County, Sweden - the Greater Stockholm HIV Cohort Study.

Jallow A, Ljunggren G, Wändell P, Carlsson AC

AIDS Care 27 (2) 142-149 [2014-10-03; online 2014-10-03]

Affiliated researcher

PubMed DOI Crossref

Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways

Ballester B, Medina-Rivera A, Schmidt D, ..., Flicek P, Wilson MD

Elife 3 (-) - [2014-10-03; online 2014-10-03]

Claudia Kutter SciLifeLab Fellow

PubMed DOI Crossref

Investigating the applicability of antibodies generated within the human protein atlas as capture agents in immunoenrichment coupled to mass spectrometry.

Boström T, Johansson HJ, Lehtiö J, Uhlén M, Hober S

J. Proteome Res. 13 (10) 4424-4435 [2014-10-03; online 2014-09-25]

Affiliated researcher

PubMed DOI Crossref

Crux: rapid open source protein tandem mass spectrometry analysis.

McIlwain S, Tamura K, Kertesz-Farkas A, ..., MacCoss MJ, Noble WS

J. Proteome Res. 13 (10) 4488-4491 [2014-10-03; online 2014-09-09]

Affiliated researcher

PubMed DOI Crossref

CanvasDB: a local database infrastructure for analysis of targeted- and whole genome re-sequencing projects.

Ameur A, Bunikis I, Enroth S, Gyllensten U

Database (Oxford) 2014 (-) - [2014-10-03; online 2014-10-03]

Affiliated researcher

PubMed DOI Crossref

Biofuels. Altered sterol composition renders yeast thermotolerant.

Caspeta L, Chen Y, Ghiaci P, ..., Petranovic D, Nielsen J

Science 346 (6205) 75-78 [2014-10-03; online 2014-10-02]

Affiliated researcher

PubMed DOI Crossref

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.

Perry JR, Day F, Elks CE, ..., Murabito JM, Ong KK

Nature 514 (7520) 92-97 [2014-10-02; online 2014-07-23]

Affiliated researcher

DOI Crossref

Wavefunction and reactivity study of benzo[a]pyrene diol epoxide and its enantiomeric forms

Lu T, Manzetti S

Struct Chem 25 (5) 1521-1533 [2014-10-00; online 2014-04-24]

Affiliated researcher

PubMed DOI Crossref

The human skeletal muscle transcriptome: sex differences, alternative splicing, and tissue homogeneity assessed with RNA sequencing.

Lindholm ME, Huss M, Solnestam BW, ..., Lundeberg J, Sundberg CJ

FASEB J. 28 (10) 4571-4581 [2014-10-00; online 2014-07-11]

Affiliated researcher

PubMed DOI Crossref

The effect of two endogenous retinoids on the mRNA expression profile in human primary keratinocytes, focusing on genes causing autosomal recessive congenital ichthyosis.

Törmä H, Bergström A, Ghiasifarahani G, Berne B

Arch. Dermatol. Res. 306 (8) 739-747 [2014-10-00; online 2014-06-13]

Affiliated researcher

PubMed DOI Crossref

Publications

5954 publications