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4992 publications

PubMed DOI Crossref
Madagascar's extraordinary biodiversity: Threats and opportunities.
Ralimanana H, Perrigo AL, Smith RJ, ..., Zizka A, Antonelli A
Science (New York, N.Y.) 378 (6623) eadf1466 [2022-12-02; online 2022-12-02]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Madagascar's extraordinary biodiversity: Evolution, distribution, and use.
Antonelli A, Smith RJ, Perrigo AL, ..., Zizka A, Ralimanana H
Science (New York, N.Y.) 378 (6623) eabf0869 [2022-12-02; online 2022-12-02]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Higher risk of severe hypoglycemia in children and adolescents with a rapid loss of C-peptide during the first 6 years after type 1 diabetes diagnosis
Grönberg A, Espes D, Carlsson P, Ludvigsson J
BMJ Open Diabetes Res Care - (-) - [2022-12-01; online 2022-11-16]
Daniel Espes SciLifeLab Fellow
PubMed DOI Crossref
Teasing apart the joint effect of demography and natural selection in the birth of a contact zone.
Li L, Milesi P, Tiret M, ..., Wu HX, Lascoux M
New Phytol. 236 (5) 1976-1987 [2022-12-00; online 2022-09-30]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
Inorganic nanoparticles for oral drug delivery: opportunities, barriers, and future perspectives
Asad S, Jacobsen AC, Teleki A
Current Opinion in Chemical Engineering 38 (-) 100869 [2022-12-00; online 2022-12-00]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
How broad is the selfing syndrome? Insights from convergent evolution of gene expression across species and tissues in the Capsella genus.
Zhang Z, Kryvokhyzha D, Orsucci M, ..., Milesi P, Lascoux M
New Phytol. 236 (6) 2344-2357 [2022-12-00; online 2022-09-30]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.
de Thonel A, Ahlskog JK, Daupin K, ..., Sistonen L, Mezger V
Nat Commun 13 (1) 7002 [2022-11-16; online 2022-11-16]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Multi-foci parallelised RESOLFT nanoscopy in an extended field-of-view.
Casas Moreno X, Pennacchietti F, Minet G, ..., Barabas F, Testa I
J Microsc - (-) - [2022-11-14; online 2022-11-14]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Genomic trajectories of a near-extinction event in the Chatham Island black robin.
von Seth J, van der Valk T, Lord E, ..., Robertson BC, Dussex N
BMC Genomics 23 (1) 747 [2022-11-10; online 2022-11-10]
DDLS Fellow Tom van der Valk
PubMed DOI Crossref
Super-Resolution Microscopy Opens New Doors to Life at the Nanoscale.
Fuhrmann M, Gockel N, Arizono M, ..., Testa I, Willig KI
J. Neurosci. 42 (45) 8488-8497 [2022-11-09; online 2022-11-10]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Grey matter morphology in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator.
Kaltsouni E, Dubol M, Wikström J, ..., Sundström-Poromaa I, Comasco E
Eur Neuropsychopharmacol 65 (-) 35-43 [2022-11-04; online 2022-11-04]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Fungal infection drives metabolic reprogramming in epithelial cells via aerobic glycolysis and an alternative TCA cycle shunt
Pellon A, Nasab SDS, Bidkhori G, ..., Shoaie S, Moyes D
- - (-) - [2022-11-01; online 2022-11-01]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Pregnancy induces pancreatic insulin secretion in women with long-standing type 1 diabetes.
Espes D, Magnusson L, Caballero-Corbalan J, ..., Casas R, Carlsson PO
BMJ Open Diabetes Res Care 10 (6) - [2022-11-00; online 2022-11-10]
Daniel Espes SciLifeLab Fellow
PubMed DOI Crossref
Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5.
Kampen S, Rodríguez D, Jørgensen M, ..., Lebon G, Carlsson J
ACS chemical biology 17 (10) 2744-2752 [2022-10-21; online 2022-09-23]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Influence of the extracellular domain size on the dynamic behavior of membrane proteins.
Gurdap CO, Wedemann L, Sych T, Sezgin E
Biophys. J. 121 (20) 3826-3836 [2022-10-18; online 2022-09-14]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Far Red-Shifted CdTe Quantum Dots for Multicolour Stimulated Emission Depletion Nanoscopy.
Alvelid J, Bucci A, Testa I
Chemphyschem - (-) e202200698 [2022-10-14; online 2022-10-14]
Ilaria Testa SciLifeLab Fellow
DOI Crossref
The heat shock protein LarA activates the Lon protease at the onset of proteotoxic stress
Omnus DJ, Fink MJ, Kallazhi A, Zaragoza MX, Jonas K
- - (-) - [2022-10-10; online 2022-10-10]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Extending fluorescence anisotropy to large complexes using reversibly switchable proteins.
Volpato A, Ollech D, Alvelid J, ..., Ingaramo M, Testa I
Nat. Biotechnol. - (-) - [2022-10-10; online 2022-10-10]
Ilaria Testa SciLifeLab Fellow
DOI Crossref
Intrinsic lipolysis rate for systematic design of lipid-based formulations
Jacobsen AC, Kabedev A, Sinko PD, ..., Bergström CAS, Teleki A
Drug Deliv. and Transl. Res. - (-) - [2022-10-08; online 2022-10-08]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
aMeta: an accurate and memory-efficient ancient Metagenomic profiling workflow
Pochon Z, Bergfeldt N, Kırdök E, ..., Unneberg P, Oskolkov N
- - (-) - [2022-10-05; online 2022-10-05]
DDLS Fellow Tom van der Valk
PubMed DOI Crossref
Molecular programming modulates hepatic lipid metabolism and adult metabolic risk in the offspring of obese mothers in a sex-specific manner.
Savva C, Helguero LA, González-Granillo M, ..., Kutter C, Korach-André M
Commun Biol 5 (1) 1057 [2022-10-04; online 2022-10-04]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Noncoding RNAs and RNA-binding proteins: emerging governors of liver physiology and metabolic diseases.
Sommerauer C, Kutter C
Am. J. Physiol., Cell Physiol. 323 (4) C1003-C1017 [2022-10-01; online 2022-08-15]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Unravelling the Phylogeny of a Common Intestinal Protist: Intrageneric Diversity of Endolimax.
Hocke EF, Jamy M, Burki F, Clark CG, Stensvold CR
Protist 173 (5) 125908 [2022-10-00; online 2022-09-07]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson's Disease.
Romero-Fernandez W, Taura JJ, Crans RAJ, ..., Fuxe K, Borroto-Escuela DO
Mol. Neurobiol. 59 (10) 5955-5969 [2022-10-00; online 2022-07-12]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Target-enriched nanopore sequencing and de novo assembly reveals co-occurrences of complex on-target genomic rearrangements induced by CRISPR-Cas9 in human cells.
Geng K, Merino LG, Wedemann L, ..., White RJ, Kutter C
Genome Res 32 (10) 1876-1891 [2022-10-00; online 2022-09-30]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Spatiotemporally controlled generation of NTPs for single-molecule studies.
Sabantsev A, Mao G, Aguirre Rivera J, ..., Khodorkovskiy M, Deindl S
Nat. Chem. Biol. 18 (10) 1144-1151 [2022-10-00; online 2022-09-21]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium
Mehregan A, Pérez-Conesa S, Zhuang Y, ..., Ulens C, Delemotte L
Biochimica et Biophysica Acta (BBA) - Biomembranes 1864 (10) 183994 [2022-10-00; online 2022-10-00]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Markov state modelling reveals heterogeneous drug-inhibition mechanism of Calmodulin.
Westerlund AM, Sridhar A, Dahl L, ..., Bodnar AY, Delemotte L
PLoS Comput Biol 18 (10) e1010583 [2022-10-00; online 2022-10-07]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Global patterns and rates of habitat transitions across the eukaryotic tree of life.
Jamy M, Biwer C, Vaulot D, ..., Massana R, Burki F
Nat Ecol Evol 6 (10) 1458-1470 [2022-10-00; online 2022-08-04]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Event-triggered STED imaging.
Alvelid J, Damenti M, Sgattoni C, Testa I
Nat. Methods 19 (10) 1268-1275 [2022-10-00; online 2022-09-08]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Integrative functional analysis uncovers metabolic differences between Candida species.
Begum N, Lee S, Portlock TJ, ..., Moyes DL, Shoaie S
Commun Biol 5 (1) 1013 [2022-09-26; online 2022-09-26]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Host-mycobiome metabolic interactions in health and disease.
Begum N, Harzandi A, Lee S, ..., Moyes DL, Shoaie S
Gut Microbes 14 (1) 2121576 [2022-09-25; online 2022-09-25]
Saeed Shoaie SciLifeLab Fellow
DOI Crossref
EukProt: A database of genome-scale predicted proteins across the diversity of eukaryotes
Richter DJ, Berney C, Strassert JFH, ..., Burki F, de Vargas C
- 2 (-) - [2022-09-20; online 2022-09-20]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Of problems and opportunities-How to treat and how to not treat crystallographic fragment screening data.
Weiss MS, Wollenhaupt J, Correy GJ, ..., Thunissen M, Pearce NM
Protein Sci. 31 (9) e4391 [2022-09-00; online 2022-08-31]
DDLS Fellow Nicholas Pearce
PubMed DOI Crossref
Microbial and human transcriptome in vaginal fluid at midgestation: Association with spontaneous preterm delivery.
Wikström T, Abrahamsson S, Bengtsson-Palme J, ..., Valentin L, Hagberg H
Clin Transl Med 12 (9) e1023 [2022-09-00; online 2022-09-15]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties.
Ragaller F, Andronico L, Sykora J, ..., Vattulainen I, Sezgin E
Open Biol 12 (9) 220175 [2022-09-00; online 2022-09-14]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation.
Stolz P, Mantero AS, Tvardovskiy A, ..., Elsässer SJ, Bultmann S
Nucleic Acids Res. 50 (15) 8491-8511 [2022-08-26; online 2022-07-30]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Evolutionary consequences of genomic deletions and insertions in the woolly mammoth genome.
van der Valk T, Dehasque M, Chacón-Duque JC, ..., Díez-Del-Molino D, Dalén L
iScience 25 (8) 104826 [2022-08-19; online 2022-08-01]
DDLS Fellow Tom van der Valk
PubMed DOI Crossref
The origin and evolution of open habitats in North America inferred by Bayesian deep learning models.
Andermann T, Strömberg CAE, Antonelli A, Silvestro D
Nat Commun 13 (1) 4833 [2022-08-17; online 2022-08-17]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Microbial functional genes are driven by gradients in sediment stoichiometry, oxygen, and salinity across the Baltic benthic ecosystem.
Broman E, Izabel-Shen D, Rodríguez-Gijón A, ..., Garcia SL, Nascimento FJA
Microbiome 10 (1) 126 [2022-08-15; online 2022-08-15]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
The anti-inflammatory peptide Catestatin blocks chemotaxis.
Muntjewerff EM, Parv K, Mahata SK, ..., Christoffersson G, van den Bogaart G
J Leukoc Biol 112 (2) 273-278 [2022-08-00; online 2021-12-22]
Gustaf Christoffersson SciLifeLab Fellow
DOI Crossref
Recent and local diversification of Central American understorey palms
Cano Á, Stauffer FW, Andermann T, ..., Perret M, Antonelli A
Global Ecol. Biogeogr. 31 (8) 1513-1525 [2022-08-00; online 2022-05-11]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Photophysiological response of Symbiodiniaceae single cells to temperature stress.
Xiao L, Johansson S, Rughöft S, ..., Tenje M, Behrendt L
ISME J 16 (8) 2060-2064 [2022-08-00; online 2022-04-26]
Fabien Burki SciLifeLab Fellow
DOI Crossref
Robust and integrative Bayesian neural networks for likelihood-free parameter inference
Wrede F, Eriksson R, Jiang R, ..., Hellander A, Singh P
- - (-) - [2022-07-18; online 2022-07-18]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Genome-scale metabolic modelling of the human gut microbiome reveals changes in the glyoxylate and dicarboxylate metabolism in metabolic disorders.
Proffitt C, Bidkhori G, Lee S, ..., Moyes DL, Shoaie S
iScience 25 (7) 104513 [2022-07-15; online 2022-06-02]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation.
Zhu K, Wang Y, Sarlus H, ..., Högberg B, Harris RA
EMBO Rep. 23 (7) e54499 [2022-07-05; online 2022-05-20]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Adenosine A2A receptor antagonists: from caffeine to selective non-xanthines.
Jacobson KA, Gao ZG, Matricon P, Eddy MT, Carlsson J
Br J Pharmacol 179 (14) 3496-3511 [2022-07-00; online 2020-06-19]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
The healthy female microbiome across body sites: effect of hormonal contraceptives and the menstrual cycle.
Krog MC, Hugerth LW, Fransson E, ..., Schuppe-Koistinen I, Nielsen HS
Hum. Reprod. 37 (7) 1525-1543 [2022-06-30; online 2022-05-14]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
HSFs drive transcription of distinct genes and enhancers during oxidative stress and heat shock.
Himanen SV, Puustinen MC, Da Silva AJ, Vihervaara A, Sistonen L
Nucleic Acids Res. 50 (11) 6102-6115 [2022-06-24; online 2022-06-11]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
The VirF21:VirF30 protein ratio is affected by temperature and impacts Shigella flexneri host cell invasion.
Skovajsová E, Colonna B, Prosseda G, Sellin ME, Di Martino ML
FEMS Microbiol. Lett. 369 (1) - [2022-06-22; online 2022-05-07]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles.
Céspedes PF, Jainarayanan A, Fernández-Messina L, ..., Sánchez-Madrid F, Dustin ML
Nat Commun 13 (1) 3460 [2022-06-16; online 2022-06-16]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Differential grey matter structure in women with premenstrual dysphoric disorder: evidence from brain morphometry and data-driven classification.
Dubol M, Stiernman L, Wikström J, ..., Bixo M, Comasco E
Transl Psychiatry 12 (1) 250 [2022-06-15; online 2022-06-15]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
GenErode: a bioinformatics pipeline to investigate genome erosion in endangered and extinct species.
Kutschera VE, Kierczak M, van der Valk T, ..., Dalén L, Díez-Del-Molino D
BMC Bioinformatics 23 (1) 228 [2022-06-13; online 2022-06-13]
DDLS Fellow Tom van der Valk
Incidensen av levercancer ökar över hela världen
Kutter C
Onkologi i Sverige - (-) - [2022-06-10; online 2022-06-10]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
FOXO1 and FOXO3 Cooperatively Regulate Innate Lymphoid Cell Development.
Luu TT, Søndergaard JN, Peña-Pérez L, ..., Månsson R, Kadri N
Front Immunol 13 (-) 854312 [2022-06-09; online 2022-06-09]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Itoh Y, Khawaja A, Laptev I, ..., Rorbach J, Amunts A
Nature - (-) - [2022-06-08; online 2022-06-08]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Erratum: Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes.
Carravilla P, Dasgupta A, Zhurgenbayeva G, ..., Sezgin E, Eggeling C
Biophys Rep (N Y) 2 (2) None [2022-06-08; online 2022-06-08]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Subtype-specific responses of hKv7.4 and hKv7.5 channels to polyunsaturated fatty acids reveal an unconventional modulatory site and mechanism.
Frampton DJA, Choudhury K, Nikesjö J, Delemotte L, Liin SI
Elife 11 (-) - [2022-06-01; online 2022-06-01]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
The relative role of plasticity and demographic history in Capsella bursa-pastoris: a common garden experiment in Asia and Europe.
Cornille A, Tiret M, Salcedo A, ..., Wright SI, Lascoux M
AoB Plants 14 (3) plac011 [2022-06-00; online 2022-04-02]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
The limits of human microRNA annotation have been met.
Fromm B, Zhong X, Tarbier M, Friedländer MR, Hackenberg M
RNA 28 (6) 781-785 [2022-06-00; online 2022-03-02]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
TGFβ selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial-mesenchymal transition.
Tsubakihara Y, Ohata Y, Okita Y, ..., Heldin CH, Moustakas A
Mol Oncol 16 (12) 2330-2354 [2022-06-00; online 2022-04-10]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Rapid in situ identification of biological specimens via DNA amplicon sequencing using miniaturized laboratory equipment.
Pomerantz A, Sahlin K, Vasiljevic N, ..., Ogden R, Prost S
Nat Protoc 17 (6) 1415-1443 [2022-06-00; online 2022-04-11]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Polycomb repressive complex 2 shields naïve human pluripotent cells from trophectoderm differentiation.
Kumar B, Navarro C, Winblad N, ..., Lanner F, Elsässer SJ
Nat. Cell Biol. 24 (6) 845-857 [2022-06-00; online 2022-05-30]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
OPUSeq simplifies detection of low-frequency DNA variants and uncovers fragmentase-associated artifacts.
Alekseenko A, Wang J, Barrett D, Pelechano V
NAR Genomics and Bioinformatics 4 (2) lqac048 [2022-06-00; online 2022-06-27]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Inhibition of Respiratory Syncytial Virus Infection by Small Non-Coding RNA Fragments.
Pålsson SA, Sekar V, Kutter C, Friedländer MR, Spetz AL
Int J Mol Sci 23 (11) - [2022-05-26; online 2022-05-26]
Claudia Kutter SciLifeLab Fellow
DOI Crossref
Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms
Ansari SR, Hempel NJ, Asad S, ..., Löbmann K, Teleki A
ACS Appl Mater Interfaces 14 (19) 21978-21988 [2022-05-18; online 2022-04-22]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Patatin-like phospholipase CapV in Escherichia coli - morphological and physiological effects of one amino acid substitution.
Li F, Cao L, Bähre H, ..., Rohde M, Römling U
NPJ Biofilms Microbiomes 8 (1) 39 [2022-05-11; online 2022-05-11]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Lipid-Protein Interactions in Plasma Membrane Organization and Function.
Sych T, Levental KR, Sezgin E
Annu Rev Biophys 51 (-) 135-156 [2022-05-09; online 2022-01-04]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Maternal prenatal depressive symptoms and toddler behavior: an umbilical cord blood epigenome-wide association study.
Kallak TK, Fransson E, Bränn E, ..., Lyle R, Skalkidou A
Transl Psychiatry 12 (1) 186 [2022-05-05; online 2022-05-05]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Scalable federated machine learning with FEDn
Ekmefjord M, Ait-Mlouk A, Alawadi S, ..., Toor S, Hellander A
- - (-) - [2022-05-00; online 2022-05-00]
Prashant Singh SciLifeLab Fellow
DOI Crossref
Direct Observation of Na,K‐ATPase Oligomers in The Plasma Membrane of Living Cells by FRET‐FCS
Nordahl L, Wennmalm S, Jönsson J, ..., Akkuratov EE, Brismar H
The FASEB Journal 36 (S1) - [2022-05-00; online 2022-05-13]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
A motile doublet form of Salmonella Typhimurium diversifies target search behavior at the epithelial surface.
Ek V, Fattinger SA, Florbrant A, ..., Eriksson J, Sellin ME
Mol. Microbiol. 117 (5) 1156-1172 [2022-05-00; online 2022-04-12]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Understanding immune signaling using advanced imaging techniques.
Brameshuber M, Klotzsch E, Ponjavic A, Sezgin E
Biochem. Soc. Trans. 50 (2) 853-866 [2022-04-29; online 2022-03-29]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Global Estimation and Mapping of the Conservation Status of Tree Species Using Artificial Intelligence.
Silva SV, Andermann T, Zizka A, Kozlowski G, Silvestro D
Front Plant Sci 13 (-) 839792 [2022-04-29; online 2022-04-29]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress.
Larsen BD, Benada J, Yung PYK, ..., Bartek J, Sørensen CS
Science (New York, N.Y.) 376 (6592) 476-483 [2022-04-29; online 2022-04-28]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
The Role of Bio‐based Excipients in the Formulation of Lipophilic Nutraceuticals
Teleki A, Tsekou C, Connolly A
- - (-) 315-336 [2022-04-19; online 2022-04-00]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Estimating Alpha, Beta, and Gamma Diversity Through Deep Learning.
Andermann T, Antonelli A, Barrett RL, Silvestro D
Front Plant Sci 13 (-) 839407 [2022-04-19; online 2022-04-19]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Irritable bowel syndrome and microbiome; Switching from conventional diagnosis and therapies to personalized interventions.
Ghaffari P, Shoaie S, Nielsen LK
J Transl Med 20 (1) 173 [2022-04-11; online 2022-04-11]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Experiences From Developing Software for Large X-Ray Crystallography-Driven Protein-Ligand Studies.
Pearce NM, Skyner R, Krojer T
Front Mol Biosci 9 (-) 861491 [2022-04-11; online 2022-04-11]
DDLS Fellow Nicholas Pearce
PubMed DOI Crossref
Grey matter correlates of affective and somatic symptoms of premenstrual dysphoric disorder.
Dubol M, Wikström J, Lanzenberger R, ..., Sundström-Poromaa I, Comasco E
Sci Rep 12 (1) 5996 [2022-04-09; online 2022-04-09]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Crowe-McAuliffe C, Murina V, Turnbull KJ, ..., Wilson DN, Hauryliuk V
Nat Commun 13 (1) 1860 [2022-04-06; online 2022-04-06]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Uniting diversity to create a more inclusive academic environment.
Delemotte L, Garcia SL, Rodríguez-Gijón A, Sezgin E, Vihervaara A
J. Cell. Sci. 135 (7) - [2022-04-01; online 2022-04-12]
Anniina Vihervaara Erdinc Sezgin Lucie Delemotte Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Giant plasma membrane vesicles to study plasma membrane structure and dynamics.
Sezgin E
Biochim Biophys Acta Biomembr 1864 (4) 183857 [2022-04-01; online 2022-01-04]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Target sequence capture of Barnadesioideae (Compositae) demonstrates the utility of low coverage loci in phylogenomic analyses.
Ferreira PL, Batista R, Andermann T, ..., Bacon CD, Antonelli A
Mol. Phylogenet. Evol. 169 (-) 107432 [2022-04-00; online 2022-02-04]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Prediction of drug candidates for clear cell renal cell carcinoma using a systems biology-based drug repositioning approach.
Li X, Shong K, Kim W, ..., Zhang C, Mardinoglu A
EBioMedicine 78 (-) 103963 [2022-04-00; online 2022-03-25]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Long-term SARS-CoV-2-specific and cross-reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology.
Laurén I, Havervall S, Ng H, ..., Thålin C, Mangsbo S
Immun Inflamm Dis 10 (4) e595 [2022-04-00; online 2022-03-30]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging.
Mishra K, Fuenzalida-Werner JP, Pennacchietti F, ..., Ntziachristos V, Stiel AC
Nat. Biotechnol. 40 (4) 598-605 [2022-04-00; online 2021-11-29]
Ilaria Testa SciLifeLab Fellow
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Acute sleep loss alters circulating fibroblast growth factor 21 levels in humans: A randomised crossover trial.
Mateus Brandão LE, Espes D, Westholm JO, ..., Benedict C, Cedernaes J
J Sleep Res 31 (2) e13472 [2022-04-00; online 2021-09-02]
Daniel Espes SciLifeLab Fellow
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A Gene Co-Expression Network-Based Drug Repositioning Approach Identifies Candidates for Treatment of Hepatocellular Carcinoma.
Yuan M, Shong K, Li X, ..., Zhang C, Mardinoglu A
Cancers (Basel) 14 (6) - [2022-03-19; online 2022-03-19]
Saeed Shoaie SciLifeLab Fellow
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Quantifying RNA synthesis at rate-limiting steps of transcription using nascent RNA-sequencing data.
Rabenius A, Chandrakumaran S, Sistonen L, Vihervaara A
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Anniina Vihervaara SciLifeLab Fellow
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minute: A MINUTE-ChIP data analysis workflow
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SciLifeLab Fellow Simon Elsässer
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Norway spruce postglacial recolonization of Fennoscandia.
Nota K, Klaminder J, Milesi P, ..., Suyama Y, Parducci L
Nat Commun 13 (1) 1333 [2022-03-14; online 2022-03-14]
Pascal Milesi SciLifeLab Fellow
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Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43.
Garcia Morato J, Hans F, von Zweydorf F, ..., Neumann M, Kahle PJ
Nat Commun 13 (1) 1223 [2022-03-09; online 2022-03-09]
SciLifeLab Fellow Simon Elsässer
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Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures.
Wood TM, Zeronian MR, Buijs N, ..., Janssen BJC, Martin NI
Chem Sci 13 (10) 2985-2991 [2022-03-09; online 2022-02-21]
DDLS Fellow Nicholas Pearce
PubMed DOI Crossref
The SWI/SNF subunit BRG1 affects alternative splicing by changing RNA binding factor interactions with nascent RNA.
Gañez-Zapater A, Mackowiak SD, Guo Y, ..., Visa N, Östlund Farrants AK
Mol. Genet. Genomics 297 (2) 463-484 [2022-03-00; online 2022-02-20]
Marc Friedländer SciLifeLab Fellow
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On the origin of TSAR: morphology, diversity and phylogeny of Telonemia.
Tikhonenkov DV, Jamy M, Borodina AS, ..., Burki F, Karpov SA
Open Biol 12 (3) 210325 [2022-03-00; online 2022-03-16]
Fabien Burki SciLifeLab Fellow
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ADAR1- and ADAR2-mediated regulation of maturation and targeting of miR-376b to modulate GABA neurotransmitter catabolism.
Widmark A, Sagredo EA, Karlström V, ..., Daniel C, Öhman M
J Biol Chem 298 (3) 101682 [2022-03-00; online 2022-02-03]
Marc Friedländer SciLifeLab Fellow
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Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction.
Begnini F, Geschwindner S, Johansson P, ..., Schiesser S, Kihlberg J
J Med Chem 65 (4) 3473-3517 [2022-02-24; online 2022-02-02]
Jens Carlsson SciLifeLab Fellow
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White matter microstructure and volume correlates of premenstrual dysphoric disorder.
Gu X, Dubol M, Stiernman L, ..., Sundström-Poromaa I, Comasco E
J Psychiatry Neurosci 47 (1) E67-E76 [2022-02-23; online 2022-02-23]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses.
Luttens A, Gullberg H, Abdurakhmanov E, ..., Danielson UH, Carlsson J
Journal of the American Chemical Society 144 (7) 2905-2920 [2022-02-23; online 2022-02-10]
Jens Carlsson SciLifeLab Fellow
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Identification of electroporation sites in the complex lipid organization of the plasma membrane.
Rems L, Tang X, Zhao F, ..., Testa I, Delemotte L
Elife 11 (-) - [2022-02-23; online 2022-02-23]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide mapping of G-quadruplex structures with CUT&Tag.
Lyu J, Shao R, Kwong Yung PY, Elsässer SJ
Nucleic Acids Res. 50 (3) e13 [2022-02-22; online 2021-11-19]
SciLifeLab Fellow Simon Elsässer
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Prevalence and correlates of current suicidal ideation in women with premenstrual dysphoric disorder.
Wikman A, Sacher J, Bixo M, ..., Comasco E, Sundström Poromaa I
BMC Womens Health 22 (1) 35 [2022-02-11; online 2022-02-11]
Erika Comasco SciLifeLab Fellow
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Genomics and adaptation in forest ecosystems.
Neophytou C, Heer K, Milesi P, ..., Rellstab C, Gugerli F
Tree Genet Genomes 18 (2) 12 [2022-02-09; online 2022-02-09]
Pascal Milesi SciLifeLab Fellow
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Expression Profiles of Estrogen-Regulated MicroRNAs in Cancer Cells.
Archer A, Kutter C, Williams C
Methods in molecular biology (Clifton, N.J.) 2418 (-) 313-343 [2022-02-05; online 2022-02-05]
Claudia Kutter SciLifeLab Fellow
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ZFP207 sustains pluripotency by coordinating OCT4 stability, alternative splicing and RNA export.
Malla S, Prasad Bhattarai D, Groza P, ..., Kutter C, Aguilo F
EMBO Rep. 23 (3) e53191 [2022-02-03; online 2022-01-17]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium.
van Rijn JM, Eriksson J, Grüttner J, ..., Svärd SG, Sellin ME
MBio 13 (1) e0002222 [2022-02-01; online 2022-02-01]
Mikael Sellin SciLifeLab Fellow
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ExSTED microscopy reveals contrasting functions of dopamine and somatostatin CSF-c neurons along the lamprey central canal
Jalalvand E, Alvelid J, Coceano G, ..., Grillner S, Testa I
Elife 11 (-) - [2022-02-01; online 2022-02-01]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Rifaximin-α reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised controlled trial.
Patel VC, Lee S, McPhail MJW, ..., Shoaie S, Shawcross DL
J Hepatol 76 (2) 332-342 [2022-02-00; online 2021-09-24]
Saeed Shoaie SciLifeLab Fellow
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<i>IUCNN</i> – Deep learning approaches to approximate species' extinction risk
Zizka A, Andermann T, Silvestro D
Diversity and Distributions 28 (2) 227-241 [2022-02-00; online 2021-12-16]
DDLS Fellow Tobias Andermann
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Meta-analysis reveals the global picture of antibiotic resistance gene prevalence across environments
Abramova A, Berendonk TU, Bengtsson-Palme J
bioRxiv preprint - (-) - [2022-01-30; online 2022-01-30]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Sequence specificity in DNA binding is mainly governed by association.
Marklund E, Mao G, Yuan J, ..., Deindl S, Elf J
Science (New York, N.Y.) 375 (6579) 442-445 [2022-01-28; online 2022-01-27]
SciLifeLab Fellow Sebastian Deindl
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Role of Cellular Metabolism during Candida-Host Interactions.
Pellon A, Begum N, Sadeghi Nasab SD, ..., Shoaie S, Moyes DL
Pathogens 11 (2) - [2022-01-28; online 2022-01-28]
Saeed Shoaie SciLifeLab Fellow
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Irisin-A Pancreatic Islet Hormone.
Norman D, Drott CJ, Carlsson PO, Espes D
Biomedicines 10 (2) - [2022-01-25; online 2022-01-25]
Daniel Espes SciLifeLab Fellow
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BioRssay: an R package for analyses of bioassays and probit graphs.
Karunarathne P, Pocquet N, Labbé P, Milesi P
Parasit Vectors 15 (1) 35 [2022-01-24; online 2022-01-24]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
CCT3-LINC00326 axis regulates hepatocarcinogenic lipid metabolism.
Søndergaard JN, Sommerauer C, Atanasoai I, ..., Barragan I, Kutter C
Gut 71 (10) 2081-2092 [2022-01-12; online 2022-01-12]
Claudia Kutter SciLifeLab Fellow
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A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo.
Hanke L, Das H, Sheward DJ, ..., Murrell B, McInerney GM
Nat Commun 13 (1) 155 [2022-01-10; online 2022-01-10]
Erdinc Sezgin SciLifeLab Fellow
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MirGeneDB 2.1: toward a complete sampling of all major animal phyla.
Fromm B, Høye E, Domanska D, ..., Friedländer MR, Peterson KJ
Nucleic Acids Res. 50 (D1) D204-D210 [2022-01-07; online 2021-12-02]
Marc Friedländer SciLifeLab Fellow
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TRP channels: branching out into the fungal kingdom.
Hellmich UA, Delemotte L
Structure 30 (1) 2-4 [2022-01-06; online 2022-01-08]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
A Genomic Perspective Across Earth's Microbiomes Reveals That Genome Size in Archaea and Bacteria Is Linked to Ecosystem Type and Trophic Strategy.
Rodríguez-Gijón A, Nuy JK, Mehrshad M, ..., Woyke T, Garcia SL
Front Microbiol 12 (-) 761869 [2022-01-05; online 2022-01-05]
Sarahi Garcia SciLifeLab Fellow
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Revisiting sORFs: overcoming challenges to identify and characterize functional microproteins.
Schlesinger D, Elsässer SJ
FEBS J. 289 (1) 53-74 [2022-01-00; online 2021-02-24]
SciLifeLab Fellow Simon Elsässer
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Putative regulation of macrophage-mediated inflammation by catestatin.
Muntjewerff EM, Christoffersson G, Mahata SK, van den Bogaart G
Trends Immunol. 43 (1) 41-50 [2022-01-00; online 2021-11-27]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Identification of dynamic mass-action biochemical reaction networks using sparse Bayesian methods.
Jiang R, Singh P, Wrede F, Hellander A, Petzold L
PLoS Comput Biol 18 (1) e1009830 [2022-01-00; online 2022-01-31]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Distinct transcription kinetics of pluripotent cell states.
Shao R, Kumar B, Lidschreiber K, ..., Cramer P, Elsässer SJ
Mol Syst Biol 18 (1) e10407 [2022-01-00; online 2022-01-13]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Cell type-specific analysis by single-cell profiling identifies a stable mammalian tRNA-mRNA interface and increased translation efficiency in neurons.
Gao W, Gallardo-Dodd CJ, Kutter C
Genome Res 32 (1) 97-110 [2022-01-00; online 2021-12-02]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Accurate spliced alignment of long RNA sequencing reads
Sahlin K, Mäkinen V
Bioinformatics 37 (24) 4643-4651 [2021-12-11; online 2021-07-24]
Kristoffer Sahlin SciLifeLab Fellow
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Systems Biology Approaches to Decipher the Underlying Molecular Mechanisms of Glioblastoma Multiforme
Kaynar A, Altay O, Li X, ..., Shoaie S, Mardinoglu A
Int J Mol Sci 22 (24) 13213 [2021-12-08; online 2021-12-08]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes.
Carravilla P, Dasgupta A, Zhurgenbayeva G, ..., Sezgin E, Eggeling C
Biophys Rep (N Y) 1 (2) None [2021-12-08; online 2021-12-08]
Erdinc Sezgin SciLifeLab Fellow
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Genomic Signatures of Sexual Selection on Pollen-Expressed Genes in Arabis alpina.
Gutiérrez-Valencia J, Fracassetti M, Horvath R, ..., Kolář F, Slotte T
Mol. Biol. Evol. - (-) - [2021-12-08; online 2021-12-08]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
What Is the Role of the Environment in the Emergence of Novel Antibiotic Resistance Genes? A Modeling Approach.
Bengtsson-Palme J, Jonsson V, Heß S
Environ. Sci. Technol. 55 (23) 15734-15743 [2021-12-07; online 2021-11-18]
DDLS Fellow Johan Bengtsson-Palme
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An open state of a voltage-gated sodium channel involving a π-helix and conserved pore-facing Asparagine
Choudhury K, Kasimova MA, McComas S, Howard RJ, Delemotte L
Biophysical Journal 121 (1) 11-22 [2021-12-07; online 2021-12-07]
Lucie Delemotte SciLifeLab Fellow
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Proactive autoscaling for edge computing systems with kubernetes
Ju L, Singh P, Toor S
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Prashant Singh SciLifeLab Fellow
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Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire.
Fattinger SA, Sellin ME, Hardt WD
Curr Opin Microbiol 64 (-) 9-18 [2021-12-00; online 2021-09-06]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
A bioinformatic platform to integrate target capture and whole genome sequences of various read depths for phylogenomics.
G Ribeiro P, Torres Jiménez MF, Andermann T, ..., Bacon CD, Matos-Maraví P
Mol. Ecol. 30 (23) 6021-6035 [2021-12-00; online 2021-10-31]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Safety in multi-assembly via paths appearing in all path covers of a DAG.
Caceres M, Mumey B, Husic E, ..., Sahlin K, Tomescu AII
IEEE/ACM Trans Comput Biol Bioinform PP (-) - [2021-11-30; online 2021-11-30]
Kristoffer Sahlin SciLifeLab Fellow
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Genomic and niche divergence in an Amazonian palm species complex
Bacon CD, Roncal J, Andermann T, ..., Tunarosa N, Antonelli A
- 197 (4) 498-512 [2021-11-29; online 2021-05-10]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Associations of prenatal exposure to mixtures of organochlorine pesticides and smoking and drinking behaviors in adolescence.
Dickerson AS, Deng Z, Ransome Y, Factor-Litvak P, Karlsson O
Environ. Res. - (-) 112431 [2021-11-27; online 2021-11-27]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Tumorigenic activity of alternative per- and polyfluoroalkyl substances (PFAS): Mechanistic in vitro studies.
Pierozan P, Cattani D, Karlsson O
Sci. Total Environ. - (-) 151945 [2021-11-26; online 2021-11-26]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Fragment-based design of selective GPCR ligands guided by free energy simulations.
Matricon P, Vo DD, Gao ZG, ..., Jacobson KA, Carlsson J
Chem. Commun. (Camb.) 57 (92) 12305-12308 [2021-11-19; online 2021-11-19]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Single cell genomics reveals plastid-lacking Picozoa are close relatives of red algae.
Schön ME, Zlatogursky VV, Singh RP, ..., Wideman JG, Burki F
Nat Commun 12 (1) 6651 [2021-11-17; online 2021-11-17]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
MapToCleave: High-throughput profiling of microRNA biogenesis in living cells.
Kang W, Fromm B, Houben AJ, ..., Biryukova I, Friedländer MR
Cell Reports 37 (7) 110015 [2021-11-16; online 2021-11-18]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Engineered Human Induced Pluripotent Cells Enable Genetic Code Expansion in Brain Organoids.
van Husen LS, Katsori AM, Meineke B, ..., Schedin-Weiss S, Elsässer SJ
Chembiochem 22 (22) 3208-3213 [2021-11-16; online 2021-09-13]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Allosteric Effect of Nanobody Binding on Ligand-Specific Active States of the β2 Adrenergic Receptor.
Chen Y, Fleetwood O, Pérez-Conesa S, Delemotte L
J Chem Inf Model - (-) - [2021-11-15; online 2021-11-15]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling.
Meineke B, Heimgärtner J, Craig AJ, ..., Moodie LWK, Elsässer SJ
Front Chem 9 (-) 768535 [2021-11-11; online 2021-11-11]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
Large-scale identification of RBP-RNA interactions by RAPseq refines essentials of post-transcriptional gene regulation
Atanasoai I, Papavasileiou S, Preiß N, Kutter C
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Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF.
Hausmann A, Felmy B, Kunz L, ..., Sellin ME, Hardt WD
J. Exp. Med. 218 (11) - [2021-11-01; online 2021-09-16]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Improving sampling of crystallographic disorder in ensemble refinement.
Ploscariu N, Burnley T, Gros P, Pearce NM
Acta Crystallogr D Struct Biol 77 (Pt 11) 1357-1364 [2021-11-01; online 2021-10-20]
DDLS Fellow Nicholas Pearce
PubMed DOI Crossref
Effective sequence similarity detection with strobemers
Sahlin K
Genome Res. 31 (11) 2080-2094 [2021-11-00; online 2021-10-19]
Kristoffer Sahlin SciLifeLab Fellow
DOI Crossref
Event-triggered STED imaging
Alvelid J, Damenti M, Testa I
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Ilaria Testa SciLifeLab Fellow
DOI Crossref
Comprehensive analysis of chemical and biological problems associated with browning agents used in aquatic studies
Scharnweber K, Peura S, Attermeyer K, ..., Tranvik LJ, Székely AJ
Limnol Oceanogr Methods - (-) - [2021-10-28; online 2021-10-28]
Sarahi Garcia SciLifeLab Fellow
DOI Crossref
Revealing the Molecular Mechanisms of Alzheimer’s Disease Based on Network Analysis
Bayraktar A, Lam S, Altay O, ..., Shoaie S, Mardinoglu A
Int J Mol Sci 22 (21) 11556 [2021-10-26; online 2021-10-26]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
The Lon protease temporally restricts polar cell differentiation events during the Caulobacter cell cycle.
Omnus DJ, Fink MJ, Szwedo K, Jonas K
Elife 10 (-) - [2021-10-25; online 2021-10-25]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Chemoselective and Highly Sensitive Quantification of Gut Microbiome and Human Metabolites.
Lin W, Conway LP, Vujasinovic M, Löhr JM, Globisch D
Angew. Chem. Int. Ed. Engl. 60 (43) 23232-23240 [2021-10-18; online 2021-09-17]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Diversity and ecology of protists revealed by metabarcoding.
Burki F, Sandin MM, Jamy M
Curr. Biol. 31 (19) R1267-R1280 [2021-10-11; online 2021-10-13]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines.
Lin W, Yang Z, Kaur A, ..., Löhr JM, Globisch D
RSC Chem Biol 2 (5) 1479-1483 [2021-10-07; online 2021-08-12]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Nanoengineered DNA origami with repurposed TOP1 inhibitors targeting myeloid cells for the mitigation of neuroinflammation
Zhu K, Wang Y, Sarlus H, ..., Högberg B, Harris RA
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Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Differential susceptibility of rat primary neurons and neural stem cells to PFOS and PFOA toxicity.
Pierozan P, Karlsson O
Toxicol. Lett. 349 (-) 61-68 [2021-10-01; online 2021-06-11]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?
Ballante F, Kooistra AJ, Kampen S, de Graaf C, Carlsson J
Pharmacol Rev 73 (4) 527-565 [2021-10-00; online 2021-12-16]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 9: Polymyxins: colistin.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06861 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 8: Pleuromutilins: tiamulin and valnemulin.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06860 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 7: Amphenicols: florfenicol and thiamphenicol.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06859 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 6: Macrolides: tilmicosin, tylosin and tylvalosin.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06858 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 5: Lincosamides: lincomycin.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06856 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 4: β-Lactams: amoxicillin and penicillin V.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06855 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 3: Amprolium.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06854 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 2: Aminoglycosides/aminocyclitols: apramycin, paromomycin, neomycin and spectinomycin.
EFSA Panel on Biological Hazards (BIOHAZ) , Allende A, Koutsoumanis K, ..., Stella P, Peixe L
EFSA J 19 (10) e06853 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 1: Methodology, general data gaps and uncertainties.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06852 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 13: Diaminopyrimidines: trimethoprim.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06865 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 12: Tetracyclines: tetracycline, chlortetracycline, oxytetracycline, and doxycycline.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06864 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 11: Sulfonamides.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06863 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 10: Quinolones: flumequine and oxolinic acid.
EFSA Panel on Biological Hazards (BIOHAZ) , Koutsoumanis K, Allende A, ..., Stella P, Peixe L
EFSA J 19 (10) e06862 [2021-10-00; online 2021-10-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Corrigendum: Ancient microRNA profiles of 14,300-yr-old canid samples confirm taxonomic origin and provide glimpses into tissue-specific gene regulation from the Pleistocene.
Fromm B, Tarbier M, Smith O, ..., Gilbert MTP, Friedländer MR
RNA 27 (10) 1291 [2021-10-00; online 2021-09-18]
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Mol Syst Biol 17 (10) - [2021-10-00; online 2021-10-25]
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Jens Carlsson SciLifeLab Fellow
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An evaluation of a FluoroSpot assay as a diagnostic tool to determine SARS-CoV-2 specific T cell responses.
Mangsbo SM, Havervall S, Laurén I, ..., Klingström J, Thålin C
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A method for intuitively extracting macromolecular dynamics from structural disorder
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Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain
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IgE cross-linking induces activation of human and mouse mast cell progenitors.
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Mikael Sellin SciLifeLab Fellow
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The long-time orphan protist Meringosphaera mediterranea Lohmann, 1902 [1903] is a centrohelid heliozoan.
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RecA finds homologous DNA by reduced dimensionality search.
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Nature 597 (7876) 426-429 [2021-09-00; online 2021-09-01]
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Draper-Joyce CJ, Bhola R, Wang J, ..., Imlach WL, Christopoulos A
Nature 597 (7877) 571-576 [2021-09-00; online 2021-09-08]
Jens Carlsson SciLifeLab Fellow
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Killing two enemies with one stone? Genomics of resistance to two sympatric pathogens in Norway spruce.
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Mol. Ecol. 30 (18) 4433-4447 [2021-09-00; online 2021-08-05]
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Synergies of Systems Biology and Synthetic Biology in Human Microbiome Studies.
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Front Microbiol 12 (-) 681982 [2021-08-31; online 2021-08-31]
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Not4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5A.
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Convolutional Neural Networks as Summary Statistics for Approximate Bayesian Computation.
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Enterotoxigenic Escherichia coli display a distinct growth phase before entry into stationary phase with shifts in tryptophan- fucose- and putrescine metabolism and degradation of neurotransmitter precursors
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Structure and Sequence-based Computational Approaches to Allosteric Signal Transduction: Application to Electromechanical Coupling in Voltage-gated Ion Channels.
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Lucie Delemotte SciLifeLab Fellow
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Lucie Delemotte SciLifeLab Fellow
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Advances in the Relationships Between Cow's Milk Protein Allergy and Gut Microbiota in Infants.
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Candidatus Methylumidiphilus Drives Peaks in Methanotrophic Relative Abundance in Stratified Lakes and Ponds Across Northern Landscapes.
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Sarahi Garcia SciLifeLab Fellow
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Angew. Chem. Int. Ed. Engl. 60 (33) 18022-18030 [2021-08-09; online 2021-07-16]
Jens Carlsson SciLifeLab Fellow
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Sample-to-answer COVID-19 nucleic acid testing using a low-cost centrifugal microfluidic platform with bead-based signal enhancement and smartphone read-out.
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Lab Chip 21 (15) 2932-2944 [2021-08-07; online 2021-06-11]
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Genome assemblies of three closely related leaf beetle species (Galerucella spp.).
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Microbial retention and resistances in stormwater quality improvement devices treating road runoff
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The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output.
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Rpb4 and Puf3 imprint and post-transcriptionally control the stability of a common set of mRNAs in yeast.
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RNA Biol 18 (8) 1206-1220 [2021-08-00; online 2020-11-01]
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PhyloFisher: A phylogenomic package for resolving eukaryotic relationships.
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PLoS Biol. 19 (8) e3001365 [2021-08-00; online 2021-08-06]
Fabien Burki SciLifeLab Fellow
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In vitro neuroprotective effects of farnesene sesquiterpene on alzheimer's disease model of differentiated neuroblastoma cell line.
Arslan ME, Türkez H, Mardinoğlu A
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Getting a grip with kirigami
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Alexandra Teleki SciLifeLab Fellow
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FEBS Lett. 595 (16) 2127-2146 [2021-08-00; online 2021-07-07]
Erdinc Sezgin SciLifeLab Fellow
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ADP-ribosyltransferases, an update on function and nomenclature.
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FEBS J. - (-) - [2021-07-29; online 2021-07-29]
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DNA methylation of Vesicular Glutamate Transporters in the mesocorticolimbic brain following early-life stress and adult ethanol exposure-an explorative study.
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Erika Comasco SciLifeLab Fellow
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Anticancer effects of novel NSAIDs derivatives on cultured human glioblastoma cells.
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Differential regulation of oxidative stress, microbiota-derived, and energy metabolites in the mouse brain during sleep.
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Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis.
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Daniel Globisch SciLifeLab Fellow
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iNetModels 2.0: an interactive visualization and database of multi-omics data.
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Nucleic Acids Res. 49 (W1) W271-W276 [2021-07-02; online 2021-04-14]
Adil Mardinoglu SciLifeLab Fellow
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The Effect of the Molecular Weight of Polyvinylpyrrolidone and the Model Drug on Laser-Induced In Situ Amorphization
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Molecules 26 (13) 4035 [2021-07-01; online 2021-07-01]
Alexandra Teleki SciLifeLab Fellow
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CRISPR/Cas9 deletions induce adverse on-target genomic effects leading to functional DNA in human cells
Geng K, Merino LG, Wedemann L, ..., White RJ, Kutter C
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Claudia Kutter SciLifeLab Fellow
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Simultaneous detection of SARS-CoV-2 and pandemic (H1N1) 2009 virus with real-time isothermal platform.
Yu L, Wang J, Li X, ..., Guo X, Yin X
Heliyon 7 (7) e07584 [2021-07-00; online 2021-07-15]
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Safety Assessments of Nickel Boride Nanoparticles on the Human Pulmonary Alveolar Cells by Using Cell Viability and Gene Expression Analyses.
Türkez H, Arslan ME, Sönmez E, ..., Açikyildiz M, Mardinoğlu A
Biol Trace Elem Res 199 (7) 2602-2611 [2021-07-00; online 2020-09-09]
Adil Mardinoglu SciLifeLab Fellow
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STED and parallelized RESOLFT optical nanoscopy of the tubular endoplasmic reticulum and its mitochondrial contacts in neuronal cells.
Damenti M, Coceano G, Pennacchietti F, Bodén A, Testa I
Neurobiol. Dis. 155 (-) 105361 [2021-07-00; online 2021-04-12]
Ilaria Testa SciLifeLab Fellow
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Recommendations for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samples.
Kubik S, Marques AC, Xing X, ..., Willig A, Xu Z
Clin. Microbiol. Infect. 27 (7) 1036.e1-1036.e8 [2021-07-00; online 2021-04-02]
SciLifeLab Fellow Vicent Pelechano
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On the origin of the widespread self-compatible allotetraploid Capsella bursa-pastoris (Brassicaceae).
Bachmann JA, Tedder A, Fracassetti M, ..., Köhler C, Slotte T
Heredity (Edinb) 127 (1) 124-134 [2021-07-00; online 2021-04-19]
SciLifeLab Fellow Tanja Slotte
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Molecular Dynamics Simulations of Ion Channels.
Carnevale V, Delemotte L, Howard RJ
Trends Biochem. Sci. 46 (7) 621-622 [2021-07-00; online 2021-04-30]
Lucie Delemotte SciLifeLab Fellow
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Distinct genetic regions are associated with differential population susceptibility to chemical exposures.
Kosnik MB, Enroth S, Karlsson O
Environ Int 152 (-) 106488 [2021-07-00; online 2021-03-10]
Oskar Karlsson SciLifeLab Fellow
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Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator.
Kaltsouni E, Fisher PM, Dubol M, ..., Comasco E, Sundström-Poromaa I
Neuropsychopharmacology 46 (8) 1460-1467 [2021-07-00; online 2021-04-29]
Erika Comasco SciLifeLab Fellow
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DNA Blocks the Lethal Effect of Human Beta-Defensin 2 Against Neisseria meningitidis.
Wassing GM, Lidberg K, Sigurlásdóttir S, ..., Jonas K, Jonsson AB
Front Microbiol 12 (-) 697232 [2021-06-30; online 2021-06-30]
Kristina Jonas SciLifeLab Fellow
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Pesticide-induced multigenerational effects on amphibian reproduction and metabolism.
Karlsson O, Svanholm S, Eriksson A, ..., Jernerén F, Berg C
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Oskar Karlsson SciLifeLab Fellow
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Accelerated regression-based summary statistics for discrete stochastic systems via approximate simulators.
Jiang RM, Wrede F, Singh P, Hellander A, Petzold LR
BMC Bioinformatics 22 (1) 339 [2021-06-23; online 2021-06-23]
Prashant Singh SciLifeLab Fellow
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The Influence of Drug–Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles
Hempel NJ, Merkl P, Knopp MM, ..., Sotiriou GA, Löbmann K
Pharmaceutics 13 (6) 917 [2021-06-21; online 2021-06-21]
Alexandra Teleki SciLifeLab Fellow
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Application of high-throughput 5'P sequencing for the study of co-translational mRNA decay.
Zhang Y, Pelechano V
STAR Protoc 2 (2) 100447 [2021-06-18; online 2021-03-31]
SciLifeLab Fellow Vicent Pelechano
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Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2.
Roxhed N, Bendes A, Dale M, ..., Fredolini C, Schwenk JM
Nat Commun 12 (1) 3695 [2021-06-17; online 2021-06-17]
SciLifeLab Fellow Simon Elsässer
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Means, Motive, and Opportunity: Do Non-Islet-Reactive Infiltrating T Cells Contribute to Autoimmunity in Type 1 Diabetes?
Rodriguez-Calvo T, Christoffersson G, Bender C, ..., Kent SC, James EA
Front Immunol 12 (-) 683091 [2021-06-16; online 2021-06-16]
Gustaf Christoffersson SciLifeLab Fellow
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Bicyclic β-Sheet Mimetics that Target the Transcriptional Coactivator β-Catenin and Inhibit Wnt Signaling.
Wendt M, Bellavita R, Gerber A, ..., Hennig S, Grossmann TN
Angew. Chem. Int. Ed. Engl. 60 (25) 13937-13944 [2021-06-14; online 2021-05-05]
DDLS Fellow Nicholas Pearce
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Leveraging breeding programs and genomic data in Norway spruce (Picea abies L. Karst) for GWAS analysis.
Chen ZQ, Zan Y, Milesi P, ..., Lascoux M, Wu HX
Genome Biol. 22 (1) 179 [2021-06-13; online 2021-06-13]
Pascal Milesi SciLifeLab Fellow
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Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet
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Mol. Pharmaceutics 18 (6) 2254-2262 [2021-06-07; online 2021-05-05]
Alexandra Teleki SciLifeLab Fellow
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The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function.
Oftedal BE, Maio S, Handel AE, ..., Maizels RM, Holländer GA
Commun Biol 4 (1) 681 [2021-06-03; online 2021-06-03]
Erdinc Sezgin SciLifeLab Fellow
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Imaging of the Glucagon Receptor in Subjects with Type 2 Diabetes.
Eriksson O, Velikyan I, Haack T, ..., Tillner J, Wagner M
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 62 (6) 833-838 [2021-06-01; online 2020-10-23]
Olof Eriksson SciLifeLab Fellow
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Unboxing mutations: Connecting mutation types with evolutionary consequences.
Berdan EL, Blanckaert A, Slotte T, ..., Westram AM, Fragata I
Mol. Ecol. 30 (12) 2710-2723 [2021-06-00; online 2021-05-19]
SciLifeLab Fellow Tanja Slotte
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Towards policies that capture the expected value of biomolecular diversity for drug discovery, human health, and well-being.
Pesic M, Egamberdieva D, Kolodziejczyk B, ..., Neergheen VS, Kagansky A
Biol Futur 72 (2) 119-125 [2021-06-00; online 2020-09-07]
SciLifeLab Fellow Simon Elsässer
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More Than Just Letters and Chemistry: Genomics Goes Mechanics.
Deindl S, Elf J
Trends Biochem. Sci. 46 (6) 431-432 [2021-06-00; online 2021-04-12]
SciLifeLab Fellow Sebastian Deindl
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Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides.
Muntjewerff EM, Tang K, Lutter L, ..., van den Bogaart G, Mahata SK
Acta Physiol 232 (2) e13655 [2021-06-00; online 2021-05-06]
Gustaf Christoffersson SciLifeLab Fellow
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Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source.
Douangamath A, Powell A, Fearon D, ..., Gorrie-Stone T, von Delft F
J Vis Exp - (171) - [2021-05-29; online 2021-05-29]
DDLS Fellow Nicholas Pearce
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Using TIF-Seq2 to investigate association between 5´ and 3´mRNA ends.
Li B, Marques S, Wang J, Pelechano V
Meth. Enzymol. 655 (-) 85-118 [2021-05-28; online 2021-05-28]
SciLifeLab Fellow Vicent Pelechano
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Perivascular Macrophages Regulate Blood Flow Following Tissue Damage.
Vågesjö E, Parv K, Ahl D, ..., Christoffersson G, Phillipson M
Circ. Res. 128 (11) 1694-1707 [2021-05-28; online 2021-04-21]
Gustaf Christoffersson SciLifeLab Fellow
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Phagocytosis and Efferocytosis by Resident Macrophages in the Mouse Pancreas.
Parv K, Westerlund N, Merchant K, ..., Lindsay RS, Christoffersson G
Front Endocrinol (Lausanne) 12 (-) 606175 [2021-05-25; online 2021-05-25]
Gustaf Christoffersson SciLifeLab Fellow
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Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives.
Bohutínská M, Vlček J, Yair S, ..., Slotte T, Kolář F
Proc. Natl. Acad. Sci. U.S.A. 118 (21) - [2021-05-25; online 2021-05-19]
SciLifeLab Fellow Tanja Slotte
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A combined approach for single-cell mRNA and intracellular protein expression analysis.
Reimegård J, Tarbier M, Danielsson M, ..., Friedländer MR, Gallant CJ
Commun Biol 4 (1) 624 [2021-05-25; online 2021-05-25]
Marc Friedländer SciLifeLab Fellow
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Microbial Community Interactions Are Sensitive to Small Changes in Temperature.
Burman E, Bengtsson-Palme J
Front Microbiol 12 (-) 672910 [2021-05-21; online 2021-05-21]
DDLS Fellow Johan Bengtsson-Palme
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The human exposome and health in the Anthropocene.
Karlsson O, Rocklöv J, Lehoux AP, ..., Blunt MJ, Birnbaum LS
Int J Epidemiol 50 (2) 378-389 [2021-05-17; online 2020-12-23]
Oskar Karlsson SciLifeLab Fellow
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A pipeline for systematic comparison of model levels and parameter inference settings applied to negative feedback gene regulation
Coulier A, Singh P, Sturrock M, Hellander A
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Prashant Singh SciLifeLab Fellow
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Phylogenomic Insights into the Origin of Primary Plastids.
Irisarri I, Strassert JFH, Burki F
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Fabien Burki SciLifeLab Fellow
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Comprehensive dataset of shotgun metagenomes from oxygen stratified freshwater lakes and ponds.
Buck M, Garcia SL, Fernandez L, ..., Bertilsson S, Peura S
Sci Data 8 (1) 131 [2021-05-14; online 2021-05-14]
Sarahi Garcia SciLifeLab Fellow
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Informing Pharmacokinetic Models With Physiological Data: Oral Population Modeling of L-Serine in Humans.
Bosley JR, Björnson E, Zhang C, ..., Borén J, Mardinoglu A
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Adil Mardinoglu SciLifeLab Fellow
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Comparative Genomics Analysis of Keratin-Degrading Chryseobacterium Species Reveals Their Keratinolytic Potential for Secondary Metabolite Production
Kang D, Shoaie S, Jacquiod S, Sørensen SJ, Ledesma-Amaro R
Microorganisms 9 (5) 1042 [2021-05-12; online 2021-05-12]
Saeed Shoaie SciLifeLab Fellow
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Freshwater Chlorobia Exhibit Metabolic Specialization among Cosmopolitan and Endemic Populations.
Garcia SL, Mehrshad M, Buck M, ..., Greening C, Peura S
mSystems 6 (3) - [2021-05-11; online 2021-05-11]
Sarahi Garcia SciLifeLab Fellow
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The Genomic Architecture and Evolutionary Fates of Supergenes.
Gutiérrez-Valencia J, Hughes PW, Berdan EL, Slotte T
Genome Biol Evol 13 (5) - [2021-05-07; online 2021-03-20]
SciLifeLab Fellow Tanja Slotte
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Environmental Enrichment Induces Epigenomic and Genome Organization Changes Relevant for Cognition.
Espeso-Gil S, Holik AZ, Bonnin S, ..., Hor CN, Ossowski S
Front Mol Neurosci 14 (-) 664912 [2021-05-05; online 2021-05-05]
Marc Friedländer SciLifeLab Fellow
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The Chaperonin GroESL Facilitates Caulobacter crescentus Cell Division by Supporting the Functions of the Z-Ring Regulators FtsA and FzlA.
Schroeder K, Heinrich K, Neuwirth I, Jonas K
MBio 12 (3) - [2021-05-04; online 2021-05-04]
Kristina Jonas SciLifeLab Fellow
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Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity.
Ghovanloo MR, Choudhury K, Bandaru TS, ..., Goodchild SJ, Ruben PC
J. Gen. Physiol. 153 (5) - [2021-05-03; online 2021-04-10]
Lucie Delemotte SciLifeLab Fellow
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Volumetric live cell imaging with three-dimensional parallelized RESOLFT microscopy.
Bodén A, Pennacchietti F, Coceano G, ..., Ratz M, Testa I
Nat. Biotechnol. 39 (5) 609-618 [2021-05-00; online 2021-01-11]
Ilaria Testa SciLifeLab Fellow
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Epithelium-autonomous NAIP/NLRC4 prevents TNF-driven inflammatory destruction of the gut epithelial barrier in Salmonella-infected mice.
Fattinger SA, Geiser P, Samperio Ventayol P, ..., Hardt WD, Sellin ME
Mucosal Immunol 14 (3) 615-629 [2021-05-00; online 2021-03-17]
Mikael Sellin SciLifeLab Fellow
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Can molecular dynamics simulations improve the structural accuracy and virtual screening performance of GPCR models?
Kapla J, Rodríguez-Espigares I, Ballante F, Selent J, Carlsson J
PLoS Comput Biol 17 (5) e1008936 [2021-05-00; online 2021-05-13]
Jens Carlsson SciLifeLab Fellow
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The Protein Quality Control Network in Caulobacter crescentus.
Schroeder K, Jonas K
Front Mol Biosci 8 (-) 682967 [2021-04-30; online 2021-04-30]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Informing NMR experiments with molecular dynamics simulations to characterize the dominant activated state of the KcsA ion channel.
Pérez-Conesa S, Keeler EG, Zhang D, Delemotte L, McDermott AE
J Chem Phys 154 (16) 165102 [2021-04-28; online 2021-05-05]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
How Does Liquid-Liquid Phase Separation in Model Membranes Reflect Cell Membrane Heterogeneity?
Sych T, Gurdap CO, Wedemann L, Sezgin E
Membranes (Basel) 11 (5) - [2021-04-28; online 2021-04-28]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers.
Samperio Ventayol P, Geiser P, Di Martino ML, ..., Eriksson J, Sellin ME
Proc. Natl. Acad. Sci. U.S.A. 118 (16) - [2021-04-20; online 2021-04-14]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Scalable machine learning-assisted model exploration and inference using Sciope.
Singh P, Wrede F, Hellander A
Bioinformatics 37 (2) 279-281 [2021-04-19; online 2020-07-25]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Stress-induced transcriptional memory accelerates promoter-proximal pause release and decelerates termination over mitotic divisions.
Vihervaara A, Mahat DB, Himanen SV, ..., Lis JT, Sistonen L
Mol. Cell 81 (8) 1715-1731.e6 [2021-04-15; online 2021-03-29]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation.
Regadas I, Dahlberg O, Vaid R, ..., Wen J, Mannervik M
Mol. Cell 81 (8) 1766-1780.e10 [2021-04-15; online 2021-02-24]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
DNA methylation in cord blood in association with prenatal depressive symptoms.
Kallak TK, Bränn E, Fransson E, ..., Lyle R, Skalkidou A
Clin Epigenetics 13 (1) 78 [2021-04-12; online 2021-04-12]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Resin-acid derivatives bind to multiple sites on the voltage-sensor domain of the Shaker potassium channel.
Silverå Ejneby M, Gromova A, Ottosson NE, ..., Elinder F, Delemotte L
J. Gen. Physiol. 153 (4) - [2021-04-05; online 2021-03-09]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Genome Size Reduction and Transposon Activity Impact tRNA Gene Diversity While Ensuring Translational Stability in Birds.
Ottenburghs J, Geng K, Suh A, Kutter C
Genome Biol Evol 13 (4) - [2021-04-05; online 2021-02-04]
Claudia Kutter SciLifeLab Fellow
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High-throughput 5′P sequencing enables the study of degradation-associated ribosome stalls
Zhang Y, Pelechano V
Cell Reports Methods 1 (1) 100001 [2021-04-02]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
The genome of Draba nivalis shows signatures of adaptation to the extreme environmental stresses of the Arctic.
Nowak MD, Birkeland S, Mandáková T, ..., Lysak MA, Brochmann C
Mol Ecol Resour 21 (3) 661-676 [2021-04-00; online 2020-11-12]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
A genomic catalog of Earth's microbiomes.
Nayfach S, Roux S, Seshadri R, ..., Kyrpides NC, Eloe-Fadrosh EA
Nat. Biotechnol. 39 (4) 499-509 [2021-04-00; online 2020-11-09]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
A molecular timescale for eukaryote evolution with implications for the origin of red algal-derived plastids.
Strassert JFH, Irisarri I, Williams TA, Burki F
Nat Commun 12 (1) 1879 [2021-03-25; online 2021-03-25]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Addressing the heterogeneity in liver diseases using biological networks.
Lam S, Doran S, Yuksel HH, ..., Uhlen M, Mardinoglu A
Brief. Bioinformatics 22 (2) 1751-1766 [2021-03-22; online 2020-03-24]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Dysbiosis of the Human Oral Microbiome During the Menstrual Cycle and Vulnerability to the External Exposures of Smoking and Dietary Sugar.
Bostanci N, Krog MC, Hugerth LW, ..., Nielsen HS, Schuppe-Koistinen I
Front. Cell. Infect. Microbiol. 11 (-) 625229 [2021-03-19; online 2021-03-19]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
The GenTree Platform: growth traits and tree-level environmental data in 12 European forest tree species.
Opgenoorth L, Dauphin B, Benavides R, ..., Aravanopoulos FA, Cavers S
Gigascience 10 (3) - [2021-03-18; online 2021-03-19]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
High Expression of LINC01268 is Positively Associated with Hepatocellular Carcinoma Progression via Regulating MAP3K7.
Jin X, Fu W, Li D, ..., Kutter C, Li Y
Onco Targets Ther 14 (-) 1753-1769 [2021-03-08; online 2021-03-08]
Claudia Kutter SciLifeLab Fellow
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ZFP207 <i>controls pluripotency by multiple post-transcriptional mechanisms</i>
Malla S, Bhattarai DP, Melguizo-Sanchis D, ..., Kutter C, Aguilo F
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Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Ulipristal Acetate for Treatment of Premenstrual Dysphoric Disorder: A Proof-of-Concept Randomized Controlled Trial
Comasco E, Kopp Kallner H, Bixo M, ..., Epperson CN, Sundström-Poromaa I
AJP 178 (3) 256-265 [2021-03-01; online 2021-03-01]
Erika Comasco SciLifeLab Fellow
DOI Crossref
The GenTree Leaf Collection: Inter‐ and intraspecific leaf variation in seven forest tree species in Europe
Benavides R, Carvalho B, Bastias CC, ..., Fady B, Valladares F
Global Ecol. Biogeogr. 30 (3) 590-597 [2021-03-00; online 2021-01-06]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson’s disease
Rosario D, Bidkhori G, Lee S, ..., Mardinoglu A, Shoaie S
Cell Reports 34 (9) 108807 [2021-03-00; online 2021-03-00]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
No evidence for a placental microbiome in human pregnancies at term.
Sterpu I, Fransson E, Hugerth LW, ..., Wiberg-Itzel E, Schuppe-Koistinen I
Am J Obstet Gynecol 224 (3) 296.e1-296.e23 [2021-03-00; online 2020-08-29]
DDLS Fellow Luisa Hugerth
DOI Crossref
3D-printing of solid lipid tablets from emulsion gels
Johannesson J, Khan J, Hubert M, Teleki A, Bergström CAS
Int J Pharm 597 (-) 120304 [2021-03-00; online 2021-03-00]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
The Organelle in the Room: Under-annotated Mitochondrial Reads Bias Coral Microbiome Analysis
Sonett D, Brown T, Bengtsson-Palme J, Padilla-Gamiño JL, Zaneveld JR
bioRxiv preprint - (-) - [2021-02-24; online 2021-02-24]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Spatial Regulation of T-Cell Signaling by Programmed Death-Ligand 1 on Wireframe DNA Origami Flat Sheets.
Fang T, Alvelid J, Spratt J, ..., Testa I, Teixeira AI
ACS Nano 15 (2) 3441-3452 [2021-02-23; online 2021-02-08]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Chenodeoxycholic Acid Modulates Bile Acid Synthesis Independent of Fibroblast Growth Factor 19 in Primary Human Hepatocytes.
Johansson H, Søndergaard JN, Jorns C, Kutter C, Ellis ECS
Front Endocrinol (Lausanne) 11 (-) 554922 [2021-02-22; online 2021-02-22]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.
Hewitt G, Borel V, Segura-Bayona S, ..., Deindl S, Boulton SJ
Mol. Cell 81 (4) 767-783.e11 [2021-02-18; online 2020-12-16]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics.
Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan DP, Lundberg E
Nature 590 (7847) 649-654 [2021-02-00; online 2021-02-24]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Phylogenomics of the tropical plant family Ochnaceae using targeted enrichment of nuclear genes and 250+ taxa
Schneider JV, Jungcurt T, Cardoso D, ..., Berberich T, Zizka G
TAXON 70 (1) 48-71 [2021-02-00; online 2020-12-31]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
NGSpeciesID: DNA barcode and amplicon consensus generation from long-read sequencing data.
Sahlin K, Lim MCW, Prost S
Ecol Evol 11 (3) 1392-1398 [2021-02-00; online 2021-01-11]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Model membrane systems to reconstitute immune cell signaling.
Céspedes PF, Beckers D, Dustin ML, Sezgin E
FEBS J. 288 (4) 1070-1090 [2021-02-00; online 2020-08-03]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Hybrid seed incompatibility in Capsella is connected to chromatin condensation defects in the endosperm.
Dziasek K, Simon L, Lafon-Placette C, ..., Slotte T, Köhler C
PLoS Genet 17 (2) e1009370 [2021-02-00; online 2021-02-11]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Epithelial inflammasomes in the defense against Salmonella gut infection.
Fattinger SA, Sellin ME, Hardt WD
Curr Opin Microbiol 59 (-) 86-94 [2021-02-00; online 2020-10-28]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Comparison of two arylsulfatases for targeted mass spectrometric analysis of microbiota-derived metabolites
Jain A, Correia MSP, Meistermann H, ..., Löhr JM, Globisch D
J Pharm Biomed Anal 195 (-) 113818 [2021-02-00; online 2021-02-00]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Character and environmental lability of cyanobacteria‐derived dissolved organic matter
Patriarca C, Sedano‐Núñez VT, Garcia SL, ..., Tranvik LJ, Hawkes JA
Limnol. Oceanogr. 66 (2) 496-509 [2021-02-00; online 2020-10-09]
Sarahi Garcia SciLifeLab Fellow
DOI Crossref
Acute kidney injury leading to CKD is associated with a persistence of metabolic dysfunction and hypertriglyceridemia
Harzandi A, Lee S, Bidkhori G, ..., Shoaie S, Sharpe CC
iScience 24 (2) 102046 [2021-02-00; online 2021-02-00]
Saeed Shoaie SciLifeLab Fellow
DOI Crossref
<i>iucn_sim</i> : a new program to simulate future extinctions based on IUCN threat status
Andermann T, Faurby S, Cooke R, Silvestro D, Antonelli A
Ecography 44 (2) 162-176 [2021-02-00; online 2020-11-10]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Epidemiological modeling in StochSS Live!
Jiang R, Jacob B, Geiger M, ..., Hellander A, Petzold L
Bioinformatics - (-) - [2021-01-29; online 2021-01-29]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Identification of ligand-specific G protein-coupled receptor states and prediction of downstream efficacy via data-driven modeling.
Fleetwood O, Carlsson J, Delemotte L
Elife 10 (-) - [2021-01-28; online 2021-01-28]
Jens Carlsson Lucie Delemotte SciLifeLab Fellow
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Cellocity: A Python package for analysis of confluent cell layer dynamics
Eriksson J, Styrström D, Sellin M
JOSS 6 (57) 2818 [2021-01-28; online 2021-01-28]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers.
Li X, Kim W, Arif M, ..., Zhang C, Mardinoglu A
Cancers (Basel) 13 (2) - [2021-01-19; online 2021-01-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Direct detection of SARS-CoV-2 using non-commercial RT-LAMP reagents on heat-inactivated samples.
Alekseenko A, Barrett D, Pareja-Sanchez Y, ..., Yin X, Pelechano V
Sci Rep 11 (1) 1820 [2021-01-19; online 2021-01-19]
SciLifeLab Fellow Simon Elsässer Vicent Pelechano
PubMed DOI Crossref
Single-Molecule, Super-Resolution, and Functional Analysis of G Protein-Coupled Receptor Behavior Within the T Cell Immunological Synapse.
Felce JH, Parolini L, Sezgin E, ..., Frater J, Dustin ML
Front Cell Dev Biol 8 (-) 608484 [2021-01-18; online 2021-01-18]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Nradd Acts as a Negative Feedback Regulator of Wnt/β-Catenin Signaling and Promotes Apoptosis.
Ozalp O, Cark O, Azbazdar Y, ..., Sezgin E, Ozhan G
Biomolecules 11 (1) - [2021-01-14; online 2021-01-14]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids.
Geiser P, Di Martino ML, Samperio Ventayol P, ..., Hellström PM, Sellin ME
MBio 12 (1) - [2021-01-12; online 2021-01-12]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae.
Rodríguez-Galán O, García-Gómez JJ, Rosado IV, ..., Kressler D, de la Cruz J
Nucleic Acids Res. 49 (1) 206-220 [2021-01-11; online 2020-12-18]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Obese mother offspring have hepatic lipidic modulation that contributes to sex-dependent metabolic adaptation later in life.
Savva C, Helguero LA, González-Granillo M, ..., Kutter C, Korach-André M
Commun Biol 4 (1) 14 [2021-01-04; online 2021-01-04]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis.
Sahlin K, Medvedev P
Nat Commun 12 (1) 2 [2021-01-04; online 2021-01-04]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
CAFE: a software suite for analysis of paired-sample transposon insertion sequencing data.
Abramova A, Osińska A, Kunche H, Burman E, Bengtsson-Palme J
Bioinformatics - (-) - [2021-01-04; online 2021-01-04]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
The effect of Toll-like receptor stimulation on the motility of regulatory T cells.
Chodaczek G, Pagni PP, Christoffersson G, ..., Wegrzyn AS, von Herrath M
J. Autoimmun. 116 (-) 102563 [2021-01-00; online 2020-11-12]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Systems biology based drug repositioning for development of cancer therapy.
Turanli B, Altay O, Borén J, ..., Arga KY, Mardinoglu A
Semin. Cancer Biol. 68 (-) 47-58 [2021-01-00; online 2019-09-27]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease.
Asad S, Wegler C, Ahl D, ..., Artursson P, Teleki A
J Pharm Sci 110 (1) 239-250 [2021-01-00; online 2020-11-04]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
News ways of understanding the complex biology of diabetes using PET.
Eriksson O, Långström B, Antoni G
Nucl. Med. Biol. 92 (-) 65-71 [2021-01-00; online 2020-04-27]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Neuroimaging the menstrual cycle: A multimodal systematic review.
Dubol M, Epperson CN, Sacher J, ..., Sundström-Poromaa I, Comasco E
Front Neuroendocrinol 60 (-) 100878 [2021-01-00; online 2020-10-22]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality.
Stebbing J, Sánchez Nievas G, Falcone M, ..., Abizanda P, Lauschke VM
Sci Adv 7 (1) - [2021-01-00; online 2021-01-01]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Ligand design by targeting a binding site water
Matricon P, Suresh RR, Gao ZG, ..., Jacobson KA, Carlsson J
Chem Sci 12 (3) 960-968 [2021-00-00; online 2021-00-00]
Jens Carlsson SciLifeLab Fellow
DOI Crossref
Investigation of the individual human sulfatome in plasma and urine samples reveals an age-dependency
Correia MSP, Thapa B, Vujasinovic M, Löhr JM, Globisch D
RSC Adv. 11 (55) 34788-34794 [2021-00-00; online 2021-00-00]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
5´XP sRNA-seq: efficient identification of transcripts with and without 5´ phosphorylation reveals evolutionary conserved small RNA.
Kugelberg U, Nätt D, Skog S, Kutter C, Öst A
RNA Biol - (-) 1-12 [2020-12-31; online 2020-12-31]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.
Lehmann LC, Bacic L, Hewitt G, ..., Boulton SJ, Deindl S
Cell Reports 33 (12) 108529 [2020-12-22; online 2020-12-29]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Ileocolonic Histopathological and Microbial Alterations in the Irritable Bowel Syndrome: A Nested Community Case-Control Study.
Talley NJ, Alexander JL, Walker MM, ..., Powell N, Andreasson A
Clin Transl Gastroenterol 12 (1) e00296 [2020-12-22; online 2020-12-22]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
Ancient microRNA profiles of a 14,300-year-old canid samples confirm taxonomic origin and give glimpses into tissue-specific gene regulation from the Pleistocene.
Fromm B, Tarbier M, Smith O, ..., Gilbert TP, Friedlander MR
RNA - (-) - [2020-12-15; online 2020-12-15]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Automated Removal of Non-homologous Sequence Stretches with PREQUAL.
Irisarri I, Burki F, Whelan S
Methods in molecular biology (Clifton, N.J.) 2231 (-) 147-162 [2020-12-09; online 2020-12-09]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development.
Malkani S, Chin CR, Cekanaviciute E, ..., Mason CE, Beheshti A
Cell Reports 33 (10) 108448 [2020-12-08; online 2020-11-25]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Microbial model communities: To understand complexity, harness the power of simplicity.
Bengtsson-Palme J
Comput Struct Biotechnol J 18 (-) 3987-4001 [2020-12-02; online 2020-12-02]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Recent advances in single-molecule fluorescence microscopy render structural biology dynamic
Bacic L, Sabantsev A, Deindl S
Current Opinion in Structural Biology 65 (-) 61-68 [2020-12-00; online 2020-12-00]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Genome-wide detection of DNA double-strand breaks by in-suspension BLISS.
Bouwman BAM, Agostini F, Garnerone S, ..., Roukos V, Crosetto N
Nat Protoc 15 (12) 3894-3941 [2020-12-00; online 2020-11-02]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Distinct pre-initiation steps in human mitochondrial translation
Khawaja A, Itoh Y, Remes C, ..., Amunts A, Rorbach J
Nat Commun 11 (1) - [2020-12-00; online 2020-06-10]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening.
Kang PW, Westerlund AM, Shi J, ..., Delemotte L, Cui J
Sci Adv 6 (50) - [2020-12-00; online 2020-12-11]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM, Amunts A
Nat Commun 11 (1) - [2020-12-00; online 2020-10-14]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Universal Single-Residue Terminal Labels for Fluorescent Live Cell Imaging of Microproteins.
Lafranchi L, Schlesinger D, Kimler KJ, Elsässer SJ
Journal of the American Chemical Society 142 (47) 20080-20087 [2020-11-25; online 2020-11-11]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Improved computational analysis of ribosome dynamics from 5′P degradome data using fivepseq
Nersisyan L, Ropat M, Pelechano V
NAR Genomics and Bioinformatics 2 (4) - [2020-11-24; online 2020-11-24]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells.
Zhan C, Bidkhori G, Schwarz H, ..., Rockberg J, Chotteau V
iScience 23 (11) 101653 [2020-11-20; online 2020-10-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Comparative dietary sulfated metabolome analysis reveals unknown metabolic interactions of the gut microbiome and the human host.
Correia MSP, Jain A, Alotaibi W, ..., Rodriguez-Mateos A, Globisch D
Free Radic. Biol. Med. 160 (-) 745-754 [2020-11-20; online 2020-09-11]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Amino Acid Modified RNA Bases as Building Blocks of an Early Earth RNA-Peptide World.
Nainytė M, Müller F, Ganazzoli G, ..., Globisch D, Carell T
Chemistry 26 (65) 14856-14860 [2020-11-20; online 2020-10-14]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Assessment of In Vitro and In Silico Protocols for Sequence-Based Characterization of the Human Vaginal Microbiome.
Hugerth LW, Pereira M, Zha Y, ..., Schuppe-Koistinen I, Engstrand L
mSphere 5 (6) - [2020-11-18; online 2020-11-18]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
Lipoprotein Particles Interact with Membranes and Transfer Their Cargo without Receptors
Plochberger B, Sych T, Weber F, ..., Stangl H, Sezgin E
Biochemistry 59 (45) 4421-4428 [2020-11-17; online 2020-11-04]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Redesigning Solvatochromic Probe Laurdan for Imaging Lipid Order Selectively in Cell Plasma Membranes.
Danylchuk DI, Sezgin E, Chabert P, Klymchenko AS
Anal. Chem. 92 (21) 14798-14805 [2020-11-03; online 2020-10-12]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Tracking the motion of the KV 1.2 voltage sensor reveals the molecular perturbations caused by a de novo mutation in a case of epilepsy.
Pantazis A, Kaneko M, Angelini M, ..., Saitta SC, Olcese R
J. Physiol. (Lond.) 598 (22) 5245-5269 [2020-11-00; online 2020-09-21]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Quantification of aromatase binding in the female human brain using [11 C]cetrozole positron emission tomography.
Jonasson M, Nordeman P, Eriksson J, ..., Lubberink M, Comasco E
J Neurosci Res 98 (11) 2208-2218 [2020-11-00; online 2020-08-06]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) induce epigenetic alterations and promote human breast cell carcinogenesis in vitro.
Pierozan P, Cattani D, Karlsson O
Arch. Toxicol. 94 (11) 3893-3906 [2020-11-00; online 2020-07-22]
Oskar Karlsson SciLifeLab Fellow
DOI Crossref
Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F
Oosterheert W, Xenaki KT, Neviani V, ..., van Bergen en Henegouwen PM, Gros P
Life Sci. Alliance 3 (11) e202000883 [2020-11-00; online 2020-09-21]
DDLS Fellow Nicholas Pearce
PubMed DOI Crossref
Differences in structure and hibernation mechanism highlight diversification of the microsporidian ribosome
Ehrenbolger K, Jespersen N, Sharma H, ..., Vossbrinck CR, Barandun J
PLoS Biol. 18 (10) e3000958 [2020-10-30; online 2020-10-30]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Potential Anticancer Effect of Carvacrol Codrugs on Human Glioblastoma Cells.
Yazici A, Marinelli L, Cacciatore I, ..., Mardinoğlu A, Türkez H
Curr Drug Deliv 18 (3) 350-356 [2020-10-29; online 2020-10-29]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Fluidity and Lipid Composition of Membranes of Peroxisomes, Mitochondria and the ER From Oleic Acid-Induced Saccharomyces cerevisiae
Reglinski K, Steinfort-Effelsberg L, Sezgin E, ..., Eggeling C, Erdmann R
Front Cell Dev Biol 8 (-) 574363 [2020-10-29; online 2020-10-29]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells.
Tarbier M, Mackowiak SD, Frade J, ..., Gallant CJ, Friedländer MR
Nat Commun 11 (1) 5445 [2020-10-28; online 2020-10-28]
Magda Bienko Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Hippocampal neural stem cells are more susceptible to the neurotoxin BMAA than primary neurons: effects on apoptosis, cellular differentiation, neurite outgrowth, and DNA methylation.
Pierozan P, Cattani D, Karlsson O
Cell Death Dis 11 (10) 910 [2020-10-24; online 2020-10-24]
Oskar Karlsson SciLifeLab Fellow
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Disease, Drugs and Dysbiosis: Understanding Microbial Signatures in Metabolic Disease and Medical Interventions.
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The past and future human impact on mammalian diversity.
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Systems Biology: A Multi-Omics Integration Approach to Metabolism and the Microbiome.
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Endocrinol Metab (Seoul) 35 (3) 507-514 [2020-09-00; online 2020-09-22]
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Integrating the "Immunome" in the Stratification of Myelodysplastic Syndromes and Future Clinical Trial Design.
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Histidyl-Proline Diketopiperazine Isomers as Multipotent Anti-Alzheimer Drug Candidates.
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Genome Biol Evol 12 (5) 522-534 [2020-05-01; online 2020-04-14]
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Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development.
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The European Research Network on Signal Transduction (ERNEST): Toward a Multidimensional Holistic Understanding of G Protein-Coupled Receptor Signaling.
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The in vitro cytotoxic, genotoxic, and oxidative damage potentials of the oral artificial sweetener aspartame on cultured human blood cells
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The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease.
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Life in the dark: far-red absorbing cyanobacteria extend photic zones deep into terrestrial caves.
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Erdinc Sezgin SciLifeLab Fellow
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A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma.
Das Mahapatra K, Pasquali L, Søndergaard JN, ..., Kristensen LS, Pivarcsi A
Sci Rep 10 (1) 3637 [2020-02-27; online 2020-02-27]
Claudia Kutter SciLifeLab Fellow
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Energy Landscapes Reveal Agonist Control of G Protein-Coupled Receptor Activation via Microswitches.
Fleetwood O, Matricon P, Carlsson J, Delemotte L
Biochemistry 59 (7) 880-891 [2020-02-25; online 2020-02-07]
Jens Carlsson Lucie Delemotte SciLifeLab Fellow
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A Guide to Carrying Out a Phylogenomic Target Sequence Capture Project.
Andermann T, Torres Jiménez MF, Matos-Maraví P, ..., Bacon CD, Antonelli A
Front Genet 10 (-) 1407 [2020-02-21; online 2020-02-21]
DDLS Fellow Tobias Andermann
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Creating Supported Plasma Membrane Bilayers Using Acoustic Pressure.
Sezgin E, Carugo D, Levental I, Stride E, Eggeling C
Membranes (Basel) 10 (2) 30 [2020-02-18; online 2020-02-18]
Erdinc Sezgin SciLifeLab Fellow
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Biophysical Characterization of Epigallocatechin-3-Gallate Effect on the Cardiac Sodium Channel Nav1.5.
Amarouch MY, Kurt H, Delemotte L, Abriel H
Molecules 25 (4) 902 [2020-02-18; online 2020-02-18]
Lucie Delemotte SciLifeLab Fellow
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Radial Organization in the Mammalian Nucleus.
Crosetto N, Bienko M
Front Genet 11 (-) 33 [2020-02-12; online 2020-02-12]
Magda Bienko SciLifeLab Fellow
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Regulation of lipid saturation without sensing membrane fluidity.
Ballweg S, Sezgin E, Doktorova M, ..., Hummer G, Ernst R
Nat Commun 11 (1) 756 [2020-02-06; online 2020-02-06]
Erdinc Sezgin SciLifeLab Fellow
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Molecular Insights from Conformational Ensembles via Machine Learning.
Fleetwood O, Kasimova MA, Westerlund AM, Delemotte L
Biophys. J. 118 (3) 765-780 [2020-02-04; online 2019-12-21]
Lucie Delemotte SciLifeLab Fellow
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Abundance and diversity of resistomes differ between healthy human oral cavities and gut.
Carr VR, Witherden EA, Lee S, ..., Gomez-Cabrero D, Moyes DL
Nat Commun 11 (1) 693 [2020-02-04; online 2020-02-04]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API.
Desvignes T, Loher P, Eilbeck K, ..., Halushka MK, Pantano L
Bioinformatics 36 (3) 698-703 [2020-02-01; online 2019-09-11]
Marc Friedländer SciLifeLab Fellow
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The molecular basis for sugar import in malaria parasites.
Qureshi AA, Suades A, Matsuoka R, ..., Delemotte L, Drew D
Nature 578 (7794) 321-325 [2020-02-00; online 2020-01-29]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Handling ties in continuous outcomes for confounder adjustment with rank-ordered logit and its application to ordinal outcomes.
Ning Y, Tan CS, Maraki A, ..., Reilly M, Støer NC
Stat Methods Med Res 29 (2) 437-454 [2020-02-00; online 2019-04-03]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Environmental impacts and limitations of third‐generation biobutanol: Life cycle assessment of n ‐butanol produced by genetically engineered cyanobacteria
Nilsson A, Shabestary K, Brandão M, Hudson EP
Journal of Industrial Ecology 24 (1) 205-216 [2020-02-00; online 2019-04-00]
Paul Hudson SciLifeLab Fellow
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Classification of clear cell renal cell carcinoma based on PKM alternative splicing.
Li X, Turanli B, Juszczak K, ..., Zhang C, Mardinoglu A
Heliyon 6 (2) e03440 [2020-02-00; online 2020-02-19]
Adil Mardinoglu SciLifeLab Fellow
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Phylogenomics and biogeography of the world's thrushes (Aves, Turdus): new evidence for a more parsimonious evolutionary history.
Batista R, Olsson U, Andermann T, ..., Ribas CC, Antonelli A
Proc. Biol. Sci. 287 (1919) 20192400 [2020-01-29; online 2020-01-22]
DDLS Fellow Tobias Andermann
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Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D.
Sayitoglu EC, Georgoudaki AM, Chrobok M, ..., Sutlu T, Duru AD
Front Immunol 11 (-) 40 [2020-01-28; online 2020-01-28]
Adil Mardinoglu SciLifeLab Fellow
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Population Genomics of Transitions to Selfing in Brassicaceae Model Systems.
Mattila TM, Laenen B, Slotte T
Methods in molecular biology (Clifton, N.J.) 2090 (-) 269-287 [2020-01-25; online 2020-01-25]
SciLifeLab Fellow Tanja Slotte
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Docking Finds GPCR Ligands in Dark Chemical Matter.
Ballante F, Rudling A, Zeifman A, ..., Loza MI, Carlsson J
J Med Chem 63 (2) 613-620 [2020-01-23; online 2020-01-13]
Jens Carlsson SciLifeLab Fellow
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Evidence of altered mucosa-associated and fecal microbiota composition in patients with Irritable Bowel Syndrome.
Sundin J, Aziz I, Nordlander S, ..., Simrén M, Öhman L
Sci Rep 10 (1) 593 [2020-01-17; online 2020-01-17]
DDLS Fellow Luisa Hugerth
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Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation.
Pagoni A, Marinelli L, Di Stefano A, ..., Vassiliou S, Cacciatore I
Eur J Med Chem 186 (-) 111880 [2020-01-15; online 2019-11-12]
Adil Mardinoglu SciLifeLab Fellow
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A set of monomeric near-infrared fluorescent proteins for multicolor imaging across scales.
Matlashov ME, Shcherbakova DM, Alvelid J, ..., Testa I, Verkhusha VV
Nat Commun 11 (1) 239 [2020-01-13; online 2020-01-13]
Ilaria Testa SciLifeLab Fellow
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Stable stimulated emission depletion imaging of extended sample regions
Alvelid J, Testa I
J. Phys. D: Appl. Phys. 53 (2) 024001 [2020-01-09; online 2019-10-25]
Ilaria Testa SciLifeLab Fellow
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MirGeneDB 2.0: the metazoan microRNA complement.
Fromm B, Domanska D, Høye E, ..., Friedländer MR, Peterson KJ
Nucleic Acids Res. 48 (D1) D1172 [2020-01-08; online 2019-10-24]
Marc Friedländer SciLifeLab Fellow
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The GenTree Dendroecological Collection, tree-ring and wood density data from seven tree species across Europe.
Martínez-Sancho E, Slámová L, Morganti S, ..., Westin J, Fonti P
Sci Data 7 (1) 1 [2020-01-02; online 2020-01-02]
Pascal Milesi SciLifeLab Fellow
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Protein aggregation in bacteria.
Schramm FD, Schroeder K, Jonas K
FEMS Microbiol Rev 44 (1) 54-72 [2020-01-01; online 2019-10-22]
Kristina Jonas SciLifeLab Fellow
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Advances in GLP-1 receptor targeting radiolabeled agent development and prospective of theranostics.
Velikyan I, Eriksson O
Theranostics 10 (1) 437-461 [2020-01-01; online 2020-01-01]
Olof Eriksson SciLifeLab Fellow
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The New Tree of Eukaryotes.
Burki F, Roger AJ, Brown MW, Simpson AGB
Trends in Ecology & Evolution 35 (1) 43-55 [2020-01-00; online 2019-10-09]
Fabien Burki SciLifeLab Fellow
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Ontogenic succession of thermokarst thaw ponds is linked to dissolved organic matter quality and microbial degradation potential
Peura S, Wauthy M, Simone D, ..., Rautio M, Bertilsson S
Limnol. Oceanogr. 65 (S1) - [2020-01-00; online 2020-01-00]
Sari Peura SciLifeLab Fellow
DOI Crossref
Non‐cyanobacterial diazotrophs dominate nitrogen‐fixing communities in permafrost thaw ponds
Fernandez L, Bertilsson S, Peura S
Limnol. Oceanogr. 65 (S1) - [2020-01-00; online 2020-01-00]
Sari Peura SciLifeLab Fellow
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Chapter 7. Bridging the Gap Between Atomistic Molecular Dynamics Simulations and Wet-lab Experimental Techniques: Applications to Membrane Proteins
Delemotte L
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Lucie Delemotte SciLifeLab Fellow
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A genome-wide transcriptomic analysis of protein-coding genes in human blood cells.
Uhlen M, Karlsson MJ, Zhong W, ..., Fagerberg L, Brodin P
Science (New York, N.Y.) 366 (6472) eaax9198 [2019-12-20; online 2019-12-21]
Adil Mardinoglu SciLifeLab Fellow
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High genetic diversity but no geographical structure of Aedes albopictus populations in Réunion Island.
Latreille AC, Milesi P, Magalon H, Mavingui P, Atyame CM
Parasit Vectors 12 (1) 597 [2019-12-19; online 2019-12-19]
Pascal Milesi SciLifeLab Fellow
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A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart.
Asp M, Giacomello S, Larsson L, ..., Sylvén C, Lundeberg J
Cell 179 (7) 1647-1660.e19 [2019-12-12; online 2019-12-14]
Magda Bienko SciLifeLab Fellow
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InfleCS: Clustering Free Energy Landscapes with Gaussian Mixtures.
Westerlund AM, Delemotte L
J Chem Theory Comput 15 (12) 6752-6759 [2019-12-10; online 2019-11-07]
Lucie Delemotte SciLifeLab Fellow
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Overeating Saturated Fat Promotes Fatty Liver and Ceramides Compared With Polyunsaturated Fat: A Randomized Trial.
Rosqvist F, Kullberg J, Ståhlman M, ..., Ahlström H, Risérus U
J. Clin. Endocrinol. Metab. 104 (12) 6207-6219 [2019-12-01; online 2019-08-02]
Olof Eriksson SciLifeLab Fellow
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Fluorescence microscopy at the molecular scale
Alvelid J, Testa I
Current Opinion in Biomedical Engineering 12 (-) 34-42 [2019-12-00; online 2019-12-00]
Ilaria Testa SciLifeLab Fellow
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Enrichment of oral microbiota in early cystic precursors to invasive pancreatic cancer.
Gaiser RA, Halimi A, Alkharaan H, ..., Del Chiaro M, Sällberg Chen M
Gut 68 (12) 2186-2194 [2019-12-00; online 2019-03-14]
DDLS Fellow Luisa Hugerth
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Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.
Wei W, Hennig BP, Wang J, ..., Steinmetz LM, Pelechano V
Genome Res 29 (12) 1974-1984 [2019-12-00; online 2019-11-18]
SciLifeLab Fellow Vicent Pelechano
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Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.
Klevstig M, Arif M, Mannila M, ..., Ehrenborg E, Borén J
J. Mol. Cell. Cardiol. 137 (-) 1-8 [2019-12-00; online 2019-09-15]
Adil Mardinoglu SciLifeLab Fellow
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Assessing the potential for assisted gene flow using past introduction of Norway spruce in southern Sweden: Local adaptation and genetic basis of quantitative traits in trees.
Milesi P, Berlin M, Chen J, ..., Karlsson B, Lascoux M
Evol Appl 12 (10) 1946-1959 [2019-12-00; online 2019-08-22]
Pascal Milesi SciLifeLab Fellow
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Helix breaking transition in the S4 of HCN channel is critical for hyperpolarization-dependent gating.
Kasimova MA, Tewari D, Cowgill JB, ..., Delemotte L, Chanda B
Elife 8 (-) - [2019-11-27; online 2019-11-27]
Lucie Delemotte SciLifeLab Fellow
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The human secretome.
Uhlén M, Karlsson MJ, Hober A, ..., Fagerberg L, Sivertsson Å
Sci Signal 12 (609) eaaz0274 [2019-11-26; online 2019-11-26]
Adil Mardinoglu SciLifeLab Fellow
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Effects of sampling strategy and DNA extraction on human skin microbiome investigations.
Bjerre RD, Hugerth LW, Boulund F, ..., Johansen JD, Engstrand L
Sci Rep 9 (1) 17287 [2019-11-21; online 2019-11-21]
DDLS Fellow Luisa Hugerth
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Metabolically Active Brown Adipose Tissue Is Found in Adult Subjects with Type 1 Diabetes.
Eriksson O, Selvaraju RK, Berglund M, Espes D
Int J Mol Sci 20 (23) 5827 [2019-11-20; online 2019-11-20]
Olof Eriksson SciLifeLab Fellow
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Structure of a mitochondrial ATP synthase with bound native cardiolipin.
Mühleip A, McComas SE, Amunts A
Elife 8 (-) - [2019-11-18; online 2019-11-18]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
More Favorable Palmitic Acid Over Palmitoleic Acid Modification of Wnt3 Ensures Its Localization and Activity in Plasma Membrane Domains.
Azbazdar Y, Ozalp O, Sezgin E, ..., Karaca E, Ozhan G
Front Cell Dev Biol 7 (-) 281 [2019-11-15; online 2019-11-15]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Systems biology perspective for studying the gut microbiota in human physiology and liver diseases.
Altay O, Nielsen J, Uhlen M, Boren J, Mardinoglu A
EBioMedicine 49 (-) 364-373 [2019-11-00; online 2019-10-18]
Adil Mardinoglu SciLifeLab Fellow
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Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome.
Barandun J, Hunziker M, Vossbrinck CR, Klinge S
Nat. Microbiol 4 (11) 1798-1804 [2019-11-00; online 2019-07-22]
Jonas Barandun SciLifeLab Fellow
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Sharing Data from Molecular Simulations.
Abraham M, Apostolov R, Barnoud J, ..., Woods C, Zhmurov A
J Chem Inf Model 59 (10) 4093-4099 [2019-10-28; online 2019-10-11]
Lucie Delemotte SciLifeLab Fellow
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CUTseq is a versatile method for preparing multiplexed DNA sequencing libraries from low-input samples.
Zhang X, Garnerone S, Simonetti M, ..., Bienko M, Crosetto N
Nat Commun 10 (1) 4732 [2019-10-18; online 2019-10-18]
Magda Bienko SciLifeLab Fellow
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Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates.
Eriksson O, Velikyan I, Haack T, ..., Pierrou S, Wagner M
Sci Rep 9 (1) 14960 [2019-10-18; online 2019-10-18]
Olof Eriksson SciLifeLab Fellow
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Dual Bioorthogonal Labeling of the Amyloid-β Protein Precursor Facilitates Simultaneous Visualization of the Protein and Its Cleavage Products.
van Husen LS, Schedin-Weiss S, Trung MN, ..., Elsässer SJ, Tjernberg LO
J. Alzheimers Dis. 72 (2) 537-548 [2019-10-15; online 2019-10-15]
SciLifeLab Fellow Simon Elsässer
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Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe.
Cardozo Pinto DF, Yang H, Pollak Dorocic I, ..., Smidt MP, Lammel S
Nat Commun 10 (1) 4633 [2019-10-11; online 2019-10-11]
Iskra Pollak Dorocic SciLifeLab Fellow
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Remodeling the genome with DNA twists.
Bowman GD, Deindl S
Science (New York, N.Y.) 366 (6461) 35-36 [2019-10-04; online 2019-10-12]
SciLifeLab Fellow Sebastian Deindl
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Industrial wastewater treatment plant enriches antibiotic resistance genes and alters the structure of microbial communities.
Bengtsson-Palme J, Milakovic M, Švecová H, ..., Grabic R, Udikovic-Kolic N
Water Res 162 (-) 437-445 [2019-10-01; online 2019-07-04]
DDLS Fellow Johan Bengtsson-Palme
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VGLUT2 rs2290045 genotype moderates environmental sensitivity to alcohol-related problems in three samples of youths.
Vrettou M, Nilsson KW, Tuvblad C, ..., Nylander I, Comasco E
Eur Child Adolesc Psychiatry 28 (10) 1329-1340 [2019-10-00; online 2019-02-25]
Erika Comasco SciLifeLab Fellow
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Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI.
Espes D, Manell E, Rydén A, ..., Jansson L, Eriksson O
Acta diabetologica 56 (10) 1113-1120 [2019-10-00; online 2019-04-26]
Olof Eriksson SciLifeLab Fellow
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Genetic basis and timing of a major mating system shift in Capsella.
Bachmann JA, Tedder A, Laenen B, ..., Castric V, Slotte T
New Phytol. 224 (1) 505-517 [2019-10-00; online 2019-08-01]
SciLifeLab Fellow Tanja Slotte
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Association between Transcription Factor AP-2B genotype, obesity, insulin resistance and dietary intake in a longitudinal birth cohort study.
Joost U, Villa I, Comasco E, ..., Veidebaum T, Harro J
Int J Obes (Lond) 43 (10) 2095-2106 [2019-10-00; online 2019-06-17]
Erika Comasco SciLifeLab Fellow
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EvoChromo: towards a synthesis of chromatin biology and evolution.
Drinnenberg IA, Berger F, Elsässer SJ, ..., Warnecke T, Wolfe KH
Development 146 (19) - [2019-09-26; online 2019-09-26]
SciLifeLab Fellow Simon Elsässer
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Cytoplasmic protein misfolding titrates Hsp70 to activate nuclear Hsf1.
Masser AE, Kang W, Roy J, ..., Friedländer MR, Andréasson C
Elife 8 (-) - [2019-09-25; online 2019-09-25]
Marc Friedländer SciLifeLab Fellow
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What industry can teach academia.
Mao Y
Science (New York, N.Y.) 365 (6459) 1342 [2019-09-20; online 2019-10-12]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells.
Kumar B, Elsässer SJ
Cell Reports 28 (12) 3274-3284.e5 [2019-09-17; online 2019-09-19]
SciLifeLab Fellow Simon Elsässer
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Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density.
Steinkühler J, Sezgin E, Urbančič I, Eggeling C, Dimova R
Commun Biol 2 (-) 337 [2019-09-13; online 2019-09-13]
Erdinc Sezgin SciLifeLab Fellow
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Strategies to Reduce or Eliminate Resistant Pathogens in the Environment
Bengtsson‐Palme J, Heß S
Antibiotic Drug Resistance - (-) 637-673 [2019-09-09; online 2019-08-23]
DDLS Fellow Johan Bengtsson-Palme
DOI Crossref
Mumame: a software tool for quantifying gene-specific point-mutations in shotgun metagenomic data
Magesh S, Jonsson V, Bengtsson-Palme J
MBMG 3 (-) - [2019-09-04; online 2019-09-04]
DDLS Fellow Johan Bengtsson-Palme
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Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b.
van den Bos RM, Pearce NM, Granneman J, Brondijk THC, Gros P
Front Immunol 10 (-) 2097 [2019-09-04; online 2019-09-04]
DDLS Fellow Nicholas Pearce
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Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism.
von Beek C, Waern I, Eriksson J, ..., Guss B, Pejler G
Cell. Microbiol. 21 (9) e13064 [2019-09-00; online 2019-07-07]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut.
Bakkeren E, Huisman JS, Fattinger SA, ..., Diard M, Hardt WD
Nature 573 (7773) 276-280 [2019-09-00; online 2019-09-04]
Mikael Sellin SciLifeLab Fellow
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Investigation of the skin microbiome: swabs vs. biopsies.
Prast-Nielsen S, Tobin AM, Adamzik K, ..., Engstrand L, Fry L
Br. J. Dermatol. 181 (3) 572-579 [2019-09-00; online 2019-05-06]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
Impact of demography on linked selection in two outcrossing Brassicaceae species.
Mattila TM, Laenen B, Horvath R, ..., Savolainen O, Slotte T
Ecol Evol 9 (17) 9532-9545 [2019-09-00; online 2019-08-13]
SciLifeLab Fellow Tanja Slotte
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Genomic data provide new insights on the demographic history and the extent of recent material transfers in Norway spruce.
Chen J, Li L, Milesi P, ..., Vendramin GG, Lascoux M
Evol Appl 12 (8) 1539-1551 [2019-09-00; online 2019-04-30]
Pascal Milesi SciLifeLab Fellow
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Early life stress and voluntary alcohol consumption in relation to Maoa methylation in male rats.
Bendre M, Granholm L, Drennan R, ..., Nylander I, Comasco E
Alcohol 79 (-) 7-16 [2019-09-00; online 2018-11-08]
Erika Comasco SciLifeLab Fellow
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Turning Up the Heat: Local Temperature Control During in vivo Imaging of Immune Cells.
Ahl D, Eriksson O, Sedin J, ..., Christoffersson G, Phillipson M
Front Immunol 10 (-) 2036 [2019-08-27; online 2019-08-27]
Gustaf Christoffersson SciLifeLab Fellow
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Nanoscale dynamics of cholesterol in the cell membrane.
Pinkwart K, Schneider F, Lukoseviciute M, ..., Eggeling C, Sezgin E
J. Biol. Chem. 294 (34) 12599-12609 [2019-08-23; online 2019-07-03]
Erdinc Sezgin SciLifeLab Fellow
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Molecular Basis and Ecological Relevance of Caulobacter Cell Filamentation in Freshwater Habitats.
Heinrich K, Leslie DJ, Morlock M, Bertilsson S, Jonas K
MBio 10 (4) - [2019-08-20; online 2019-08-20]
Kristina Jonas SciLifeLab Fellow
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Progress towards the Tree of Eukaryotes.
Keeling PJ, Burki F
Curr. Biol. 29 (16) R808-R817 [2019-08-19; online 2019-08-21]
Fabien Burki SciLifeLab Fellow
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MRPS25 mutations impair mitochondrial translation and cause encephalomyopathy.
Bugiardini E, Mitchell AL, Rosa ID, ..., Pitceathly RDS, Spinazzola A
Hum. Mol. Genet. 28 (16) 2711-2719 [2019-08-15; online 2019-05-01]
Alexey Amunts SciLifeLab Fellow
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LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer.
Cadenas C, Vosbeck S, Edlund K, ..., Marchan R, Hengstler JG
Int. J. Cancer 145 (4) 901-915 [2019-08-15; online 2019-02-07]
Adil Mardinoglu SciLifeLab Fellow
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Chemoselective probe for detailed analysis of ketones and aldehydes produced by gut microbiota in human samples.
Conway LP, Garg N, Lin W, ..., Löhr JM, Globisch D
Chem. Commun. (Camb.) 55 (62) 9080-9083 [2019-08-11; online 2019-07-09]
Daniel Globisch SciLifeLab Fellow
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DiscoverY: a classifier for identifying Y chromosome sequences in male assemblies.
Rangavittal S, Stopa N, Tomaszkiewicz M, ..., Makova KD, Medvedev P
BMC Genomics 20 (1) 641 [2019-08-09; online 2019-08-09]
Kristoffer Sahlin SciLifeLab Fellow
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The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5' structure element.
Romilly C, Deindl S, Wagner EGH
Proc. Natl. Acad. Sci. U.S.A. 116 (32) 15901-15906 [2019-08-06; online 2019-07-18]
SciLifeLab Fellow Sebastian Deindl
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Tools for Bioimaging Pancreatic β Cells in Diabetes.
Kang NY, Soetedjo AAP, Amirruddin NS, ..., Eriksson O, Teo AKK
Trends in molecular medicine 25 (8) 708-722 [2019-08-00; online 2019-06-06]
Olof Eriksson SciLifeLab Fellow
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Strategies for increasing the throughput of super-resolution microscopies.
Mahecic D, Testa I, Griffié J, Manley S
Curr Opin Chem Biol 51 (-) 84-91 [2019-08-00; online 2019-06-15]
Ilaria Testa SciLifeLab Fellow
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Single-cell expression noise and gene-body methylation in Arabidopsis thaliana.
Horvath R, Laenen B, Takuno S, Slotte T
Heredity (Edinb) 123 (2) 81-91 [2019-08-00; online 2019-01-16]
SciLifeLab Fellow Tanja Slotte
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Hypothalamic-pituitary-adrenal axis responsiveness, startle response, and sensorimotor gating in late pregnancy.
Breedh J, Comasco E, Hellgren C, ..., Skalkidou A, Poromaa IS
Psychoneuroendocrinology 106 (-) 1-8 [2019-08-00; online 2019-03-15]
Erika Comasco SciLifeLab Fellow
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Human prenatal exposure to polychlorinated biphenyls (PCBs) and risk behaviors in adolescence.
Dickerson AS, Ransome Y, Karlsson O
Environ Int 129 (-) 247-255 [2019-08-00; online 2019-05-27]
Oskar Karlsson SciLifeLab Fellow
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Elucidating the Reprograming of Colorectal Cancer Metabolism Using Genome-Scale Metabolic Modeling.
Zhang C, Aldrees M, Arif M, ..., Mardinoglu A, Aziz MA
Front Oncol 9 (-) 681 [2019-07-30; online 2019-07-30]
Adil Mardinoglu SciLifeLab Fellow
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Constitutive Serotonin Transporter Reduction Resembles Maternal Separation with Regard to Stress-Related Gene Expression.
Comasco E, Schijven D, de Maeyer H, ..., Sundström-Poromaa I, Olivier JDA
ACS Chem Neurosci 10 (7) 3132-3142 [2019-07-17; online 2019-01-23]
Erika Comasco SciLifeLab Fellow
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The Potential Use of Metabolic Cofactors in Treatment of NAFLD.
Mardinoglu A, Ural D, Zeybel M, ..., Uhlén M, Borén J
Nutrients 11 (7) 1578 [2019-07-12; online 2019-07-12]
Adil Mardinoglu SciLifeLab Fellow
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Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nirwan N, Itoh Y, Singh P, ..., Amunts A, Saikrishnan K
Nat Commun 10 (1) 3058 [2019-07-11; online 2019-07-11]
Alexey Amunts SciLifeLab Fellow
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Coupled Enzymatic Treatment and Mass Spectrometric Analysis for Identification of Glucuronidated Metabolites in Human Samples.
Correia MSP, Rao M, Ballet C, Globisch D
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Daniel Globisch SciLifeLab Fellow
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Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862 (7) 697-705 [2019-07-00; online 2018-01-31]
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Plasma Proteomics Analysis Reveals Dysregulation of Complement Proteins and Inflammation in Acquired Obesity-A Study on Rare BMI-Discordant Monozygotic Twin Pairs.
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Outlining the proton-conduction pathway in otopetrin channels.
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Lucie Delemotte SciLifeLab Fellow
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GPR44 as a Target for Imaging Pancreatic Beta-Cell Mass.
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Front. Ecol. Evol. 7 (-) - [2019-06-20; online 2019-06-20]
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Pierozan P, Karlsson O
Cell Death Dis 10 (7) 478 [2019-06-17; online 2019-06-17]
Oskar Karlsson SciLifeLab Fellow
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Hunziker M, Barandun J, Buzovetsky O, ..., Molina H, Klinge S
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Colitis-induced colorectal cancer and intestinal epithelial estrogen receptor beta impact gut microbiota diversity.
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Int. J. Cancer 144 (12) 3086-3098 [2019-06-15; online 2019-01-11]
DDLS Fellow Luisa Hugerth
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RMetD2: a tool for integration of relative transcriptomics data into Genome-scale metabolic models
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Regulatory Immune Mechanisms beyond Regulatory T Cells.
Christoffersson G, von Herrath M
Trends Immunol. 40 (6) 482-491 [2019-06-00; online 2019-05-14]
Gustaf Christoffersson SciLifeLab Fellow
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Growth-driven displacement of protein aggregates along the cell length ensures partitioning to both daughter cells in Caulobacter crescentus.
Schramm FD, Schroeder K, Alvelid J, Testa I, Jonas K
Mol. Microbiol. 111 (6) 1430-1448 [2019-06-00; online 2019-04-03]
Ilaria Testa Kristina Jonas SciLifeLab Fellow
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Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects.
Bergström CAS, Box K, Holm R, ..., Schäfer KJ, Teleki A
Eur J Pharm Biopharm 139 (-) 101-114 [2019-06-00; online 2019-03-09]
Alexandra Teleki SciLifeLab Fellow
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Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract.
Furter M, Sellin ME, Hansson GC, Hardt WD
Cell Reports 27 (9) 2665-2678.e3 [2019-05-28; online 2019-05-30]
Mikael Sellin SciLifeLab Fellow
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Barcoded Consortium Infections Resolve Cell Type-Dependent Salmonella enterica Serovar Typhimurium Entry Mechanisms.
Di Martino ML, Ek V, Hardt WD, Eriksson J, Sellin ME
MBio 10 (3) - [2019-05-21; online 2019-05-21]
Mikael Sellin SciLifeLab Fellow
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Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production.
Paivandy A, Eriksson J, Melo FR, Sellin ME, Pejler G
Cell death discovery 5 (1) 95 [2019-05-15; online 2019-05-15]
Mikael Sellin SciLifeLab Fellow
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EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks.
Domingo-Prim J, Endara-Coll M, Bonath F, ..., Huertas P, Visa N
Nat Commun 10 (1) 2135 [2019-05-13; online 2019-05-13]
Marc Friedländer SciLifeLab Fellow
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Mucosal-associated invariant T cells and oral microbiome in persistent apical periodontitis.
Davanian H, Gaiser RA, Silfverberg M, ..., Engstrand L, Sällberg Chen M
Int J Oral Sci 11 (2) 16 [2019-05-09; online 2019-05-09]
DDLS Fellow Luisa Hugerth
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Mucispirillum schaedleri Antagonizes Salmonella Virulence to Protect Mice against Colitis.
Herp S, Brugiroux S, Garzetti D, ..., Berry D, Stecher B
Cell Host Microbe 25 (5) 681-694.e8 [2019-05-08; online 2019-04-18]
Mikael Sellin SciLifeLab Fellow
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Multi-Omic Data Interpretation to Repurpose Subtype Specific Drug Candidates for Breast Cancer.
Turanli B, Karagoz K, Bidkhori G, ..., Mardinoglu A, Arga KY
Front Genet 10 (-) 420 [2019-05-07; online 2019-05-07]
Adil Mardinoglu SciLifeLab Fellow
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Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration.
Li D, Kular L, Vij M, ..., Jagodic M, Landén NX
Proc. Natl. Acad. Sci. U.S.A. 116 (19) 9443-9452 [2019-05-07; online 2019-04-24]
Magda Bienko SciLifeLab Fellow
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Long Time-Scale Atomistic Simulations of the Structure and Dynamics of Transcription Factor-DNA Recognition.
Liao Q, Lüking M, Krüger DM, ..., Kasson PM, Lynn Kamerlin SC
J Phys Chem B 123 (17) 3576-3590 [2019-05-02; online 2019-04-18]
SciLifeLab Fellow Sebastian Deindl
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Towards the new normal: Transcriptomic convergence and genomic legacy of the two subgenomes of an allopolyploid weed (Capsella bursa-pastoris).
Kryvokhyzha D, Milesi P, Duan T, ..., Glémin S, Lascoux M
PLoS Genet 15 (5) e1008131 [2019-05-00; online 2019-05-13]
Pascal Milesi SciLifeLab Fellow
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Stress-related genetic polymorphisms in association with peripartum depression symptoms and stress hormones: A longitudinal population-based study.
Skalkidou A, Poromaa IS, Iliadis SI, ..., Freyhult E, Comasco E
Psychoneuroendocrinology 103 (-) 296-305 [2019-05-00; online 2019-02-07]
Erika Comasco SciLifeLab Fellow
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<scp>CoordinateCleaner</scp> : Standardized cleaning of occurrence records from biological collection databases
Zizka A, Silvestro D, Andermann T, ..., Zizka V, Antonelli A
Methods Ecol Evol 10 (5) 744-751 [2019-05-00; online 2019-02-24]
DDLS Fellow Tobias Andermann
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Non-Invasive Imaging Methodologies for Assessment of Radiation Damage to Bone Marrow and Kidneys from Peptide Receptor Radionuclide Therapy.
Ahlstedt J, Johansson E, Sydoff M, ..., Gram M, Eriksson O
Neuroendocrinology 110 (1-2) 130-138 [2019-04-19; online 2019-04-19]
Olof Eriksson SciLifeLab Fellow
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Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling.
Sabantsev A, Levendosky RF, Zhuang X, Bowman GD, Deindl S
Nat Commun 10 (1) 1720 [2019-04-12; online 2019-04-12]
SciLifeLab Fellow Sebastian Deindl
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Receptor-Independent Transfer of Low Density Lipoprotein Cargo to Biomembranes.
Axmann M, Sezgin E, Karner A, ..., Stangl H, Plochberger B
Nano Lett. 19 (4) 2562-2567 [2019-04-10; online 2019-03-08]
Erdinc Sezgin SciLifeLab Fellow
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iFISH is a publically available resource enabling versatile DNA FISH to study genome architecture.
Gelali E, Girelli G, Matsumoto M, ..., Crosetto N, Bienko M
Nat Commun 10 (1) 1636 [2019-04-09; online 2019-04-09]
Magda Bienko SciLifeLab Fellow
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System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection.
Garcia-Moreno M, Noerenberg M, Ni S, ..., Mohammed S, Castello A
Mol. Cell 74 (1) 196-211.e11 [2019-04-04; online 2019-02-21]
SciLifeLab Fellow Vicent Pelechano
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Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes.
Harms MJ, Li Q, Lee S, ..., Spalding KL, Boucher J
Cell Reports 27 (1) 213-225.e5 [2019-04-02; online 2019-04-04]
Adil Mardinoglu SciLifeLab Fellow
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Case Reports of Pre-clinical Replication Studies in Metabolism and Diabetes.
von Herrath M, Pagni PP, Grove K, ..., Karlsen AE, Petersen JS
Cell Metab. 29 (4) 795-802 [2019-04-02; online 2019-03-14]
Gustaf Christoffersson SciLifeLab Fellow
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New Phylogenomic Analysis of the Enigmatic Phylum Telonemia Further Resolves the Eukaryote Tree of Life.
Strassert JFH, Jamy M, Mylnikov AP, Tikhonenkov DV, Burki F
Mol. Biol. Evol. 36 (4) 757-765 [2019-04-01; online 2019-01-23]
Fabien Burki SciLifeLab Fellow
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Synthesis and preclinical evaluation of the CRTH2 antagonist [11C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass.
Eriksson J, Roy T, Sawadjoon S, ..., Eriksson O, Odell LR
Nucl. Med. Biol. 71 (-) 1-10 [2019-04-00; online 2019-04-13]
Olof Eriksson SciLifeLab Fellow
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Measuring nanoscale diffusion dynamics in cellular membranes with super-resolution STED-FCS.
Sezgin E, Schneider F, Galiani S, ..., Lagerholm BC, Eggeling C
Nat Protoc 14 (4) 1054-1083 [2019-04-00; online 2019-03-06]
Erdinc Sezgin SciLifeLab Fellow
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Liver macrophages regulate systemic metabolism through non-inflammatory factors.
Morgantini C, Jager J, Li X, ..., Bajgar A, Aouadi M
Nat Metab 1 (4) 445-459 [2019-04-00; online 2019-03-25]
Claudia Kutter SciLifeLab Fellow
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Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning.
Turanli B, Zhang C, Kim W, ..., Arga KY, Mardinoglu A
EBioMedicine 42 (-) 386-396 [2019-04-00; online 2019-03-21]
Adil Mardinoglu SciLifeLab Fellow
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A whole-brain atlas of monosynaptic input targeting four different cell types in the medial prefrontal cortex of the mouse.
Ährlund-Richter S, Xuan Y, van Lunteren JA, ..., Meletis K, Carlén M
Nat. Neurosci. 22 (4) 657-668 [2019-04-00; online 2019-03-18]
Iskra Pollak Dorocic SciLifeLab Fellow
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Comprehensive kinetic and substrate specificity analysis of an arylsulfatase from Helix pomatia using mass spectrometry.
Correia MSP, Ballet C, Meistermann H, Conway LP, Globisch D
Bioorg. Med. Chem. 27 (6) 955-962 [2019-03-15; online 2019-01-30]
Daniel Globisch SciLifeLab Fellow
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Expression of PD-L1 and PD-1 in Chemoradiotherapy-Naïve Esophageal and Gastric Adenocarcinoma: Relationship With Mismatch Repair Status and Survival.
Svensson MC, Borg D, Zhang C, ..., Leandersson K, Jirström K
Front Oncol 9 (-) 136 [2019-03-13; online 2019-03-13]
Adil Mardinoglu SciLifeLab Fellow
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Vertical stratification of bacteria and archaea in sediments of a small boreal humic lake.
Rissanen AJ, Peura S, Mpamah PA, ..., Mäki A, Nykänen H
FEMS Microbiol. Lett. 366 (5) - [2019-03-01; online 2019-02-27]
Sari Peura SciLifeLab Fellow
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Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function.
Liu Z, Zhang C, Lee S, ..., Boren J, Mardinoglu A
Metab. Eng. 52 (-) 263-272 [2019-03-00; online 2019-01-04]
Adil Mardinoglu SciLifeLab Fellow
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Plant microRNAs in human sera are likely contaminants.
Fromm B, Kang W, Rovira C, ..., Friedländer MR, Tosar JP
J Nutr Biochem 65 (-) 139-140 [2019-03-00; online 2018-09-05]
Marc Friedländer SciLifeLab Fellow
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Pervasive population genomic consequences of genome duplication in Arabidopsis arenosa.
Monnahan P, Kolář F, Baduel P, ..., Bomblies K, Yant L
Nat Ecol Evol 3 (3) 457-468 [2019-03-00; online 2019-02-25]
SciLifeLab Fellow Tanja Slotte
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Long-term balancing selection drives evolution of immunity genes in Capsella.
Koenig D, Hagmann J, Li R, ..., Wright SI, Weigel D
Elife 8 (-) - [2019-02-26; online 2019-02-26]
SciLifeLab Fellow Tanja Slotte
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Evolutionary Implications of the microRNA- and piRNA Complement of Lepidodermella squamata (Gastrotricha).
Fromm B, Tosar JP, Aguilera F, ..., Bachmann L, Hejnol A
Noncoding RNA 5 (1) 19 [2019-02-22; online 2019-02-22]
Marc Friedländer SciLifeLab Fellow
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First-in-class positron emission tomography tracer for the glucagon receptor.
Velikyan I, Haack T, Bossart M, ..., Wagner M, Eriksson O
EJNMMI Res 9 (1) 17 [2019-02-15; online 2019-02-15]
Olof Eriksson SciLifeLab Fellow
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Heterogeneity of Metabolic Defects in Type 2 Diabetes and Its Relation to Reactive Oxygen Species and Alterations in Beta-Cell Mass.
Elksnis A, Martinell M, Eriksson O, Espes D
Front. Physiol. 10 (-) 107 [2019-02-13; online 2019-02-13]
Olof Eriksson SciLifeLab Fellow
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A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection.
Wright SC, Kozielewicz P, Kowalski-Jahn M, ..., Carlsson J, Schulte G
Nat Commun 10 (1) 667 [2019-02-08; online 2019-02-08]
Jens Carlsson SciLifeLab Fellow
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Kinetic modeling of the Calvin cycle identifies flux control and stable metabolomes in Synechocystis carbon fixation.
Janasch M, Asplund-Samuelsson J, Steuer R, Hudson EP
J. Exp. Bot. 70 (3) 973-983 [2019-02-05; online 2018-10-30]
Paul Hudson SciLifeLab Fellow
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Structural Patching Fosters Divergence of Mitochondrial Ribosomes.
Petrov AS, Wood EC, Bernier CR, ..., Brown A, Amunts A
Mol. Biol. Evol. 36 (2) 207-219 [2019-02-01; online 2018-12-06]
Alexey Amunts SciLifeLab Fellow
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Smart scanning for low-illumination and fast RESOLFT nanoscopy in vivo.
Dreier J, Castello M, Coceano G, ..., Vicidomini G, Testa I
Nat Commun 10 (1) 556 [2019-02-01; online 2019-02-01]
Ilaria Testa SciLifeLab Fellow
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Transcription-driven chromatin repression of Intragenic transcription start sites.
Nielsen M, Ard R, Leng X, ..., Pelechano V, Marquardt S
PLoS Genet 15 (2) e1007969 [2019-02-00; online 2019-02-01]
SciLifeLab Fellow Vicent Pelechano
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Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysis.
Benfeitas R, Bidkhori G, Mukhopadhyay B, ..., Kunos G, Mardinoglu A
EBioMedicine 40 (-) 471-487 [2019-02-00; online 2018-12-31]
Adil Mardinoglu SciLifeLab Fellow
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Discovery of KIRREL as a biomarker for prognostic stratification of patients with thin melanoma.
Lundgren S, Fagerström-Vahman H, Zhang C, ..., Nodin B, Jirström K
Biomark Res 7 (1) 1 [2019-01-14; online 2019-01-14]
Adil Mardinoglu SciLifeLab Fellow
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Diarrheal bacterial pathogens and multi-resistant enterobacteria in the Choqueyapu River in La Paz, Bolivia.
Guzman-Otazo J, Gonzales-Siles L, Poma V, ..., Iñiguez V, Sjöling Å
PLoS ONE 14 (1) e0210735 [2019-01-14; online 2019-01-14]
DDLS Fellow Johan Bengtsson-Palme
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Negative Association Between Allopregnanolone and Cerebral Serotonin Transporter Binding in Healthy Women of Fertile Age.
Sundström Poromaa I, Comasco E, Bäckström T, ..., Jensen P, Frokjaer VG
Front Psychol 9 (-) 2767 [2019-01-11; online 2019-01-11]
Erika Comasco SciLifeLab Fellow
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The Circulating Transcriptome as a Source of Biomarkers for Melanoma.
Solé C, Tramonti D, Schramm M, ..., Middleton MR, Lawrie CH
Cancers (Basel) 11 (1) 70 [2019-01-10; online 2019-01-10]
Marc Friedländer SciLifeLab Fellow
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Decreased Snow Cover Stimulates Under-Ice Primary Producers but Impairs Methanotrophic Capacity.
Garcia SL, Szekely AJ, Bergvall C, Schattenhofer M, Peura S
mSphere 4 (1) - [2019-01-09; online 2019-01-09]
Sarahi Garcia Sari Peura SciLifeLab Fellow
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The UNITE database for molecular identification of fungi: handling dark taxa and parallel taxonomic classifications.
Nilsson RH, Larsson KH, Taylor AFS, ..., Kõljalg U, Abarenkov K
Nucleic Acids Res. 47 (D1) D259-D264 [2019-01-08; online 2018-10-30]
DDLS Fellow Johan Bengtsson-Palme
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Ascetosporea.
Bass D, Ward GM, Burki F
Curr. Biol. 29 (1) R7-R8 [2019-01-07; online 2019-01-09]
Fabien Burki SciLifeLab Fellow
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The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium.
Westermann AJ, Venturini E, Sellin ME, ..., Hardt WD, Vogel J
MBio 10 (1) - [2019-01-02; online 2019-01-02]
Mikael Sellin SciLifeLab Fellow
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A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System.
de Jong JW, Afjei SA, Pollak Dorocic I, ..., Deisseroth K, Lammel S
Neuron 101 (1) 133-151.e7 [2019-01-02; online 2018-11-29]
Iskra Pollak Dorocic SciLifeLab Fellow
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Large expert-curated database for benchmarking document similarity detection in biomedical literature search.
Brown P, RELISH Consortium , Zhou Y
Database (Oxford) 2019 (-) - [2019-01-01; online 2019-01-01]
DDLS Fellow Johan Bengtsson-Palme
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Allele Phasing Greatly Improves the Phylogenetic Utility of Ultraconserved Elements.
Andermann T, Fernandes AM, Olsson U, ..., Faircloth BC, Antonelli A
Syst. Biol. 68 (1) 32-46 [2019-01-01; online 2018-05-18]
DDLS Fellow Tobias Andermann
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Revisions to the Classification, Nomenclature, and Diversity of Eukaryotes.
Adl SM, Bass D, Lane CE, ..., Zlatogursky V, Zhang Q
J. Eukaryot. Microbiol. 66 (1) 4-119 [2019-01-00; online 2018-09-27]
Fabien Burki SciLifeLab Fellow
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Phylogenomics supports the monophyly of the Cercozoa.
Irwin NAT, Tikhonenkov DV, Hehenberger E, ..., Burki F, Keeling PJ
Mol. Phylogenet. Evol. 130 (-) 416-423 [2019-01-00; online 2018-10-11]
Fabien Burki SciLifeLab Fellow
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Introducing ribosomal tandem repeat barcoding for fungi.
Wurzbacher C, Larsson E, Bengtsson-Palme J, ..., Kagami M, Nilsson RH
Mol Ecol Resour 19 (1) 118-127 [2019-01-00; online 2018-10-24]
DDLS Fellow Johan Bengtsson-Palme
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Nanostructured Minerals and Vitamins for Food Fortification and Food Supplementation
Knijnenburg JTN, Posavec L, Teleki A
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Alexandra Teleki SciLifeLab Fellow
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Assessment and Management of Risks Associated With Antibiotic Resistance in the Environment
Bengtsson-Palme J
Management of Emerging Public Health Issues and Risks: Multidisciplinary Approaches to the Changing Environment - (-) 243-263 [2019-00-00; online 2019-00-00]
DDLS Fellow Johan Bengtsson-Palme
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The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass.
Jahan M, Johnström P, Selvaraju RK, ..., Halldin C, Eriksson O
EJNMMI Res 8 (1) 113 [2018-12-27; online 2018-12-27]
Olof Eriksson SciLifeLab Fellow
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CD45 exclusion- and cross-linking-based receptor signaling together broaden FcεRI reactivity.
Felce JH, Sezgin E, Wane M, ..., Eggeling C, Davis SJ
Sci Signal 11 (561) - [2018-12-18; online 2018-12-18]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
acI Actinobacteria Assemble a Functional Actinorhodopsin with Natively Synthesized Retinal.
Dwulit-Smith JR, Hamilton JJ, Stevenson DM, ..., McMahon KD, Forest KT
Applied and environmental microbiology 84 (24) - [2018-12-15; online 2018-11-30]
Sarahi Garcia SciLifeLab Fellow
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Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks.
Bonath F, Domingo-Prim J, Tarbier M, Friedländer MR, Visa N
Nucleic Acids Res. 46 (22) 11869-11882 [2018-12-14; online 2018-11-13]
Marc Friedländer SciLifeLab Fellow
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Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes.
Bidkhori G, Benfeitas R, Klevstig M, ..., Boren J, Mardinoglu A
Proc. Natl. Acad. Sci. U.S.A. 115 (50) E11874-E11883 [2018-12-11; online 2018-11-27]
Adil Mardinoglu SciLifeLab Fellow
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miRTrace reveals the organismal origins of microRNA sequencing data.
Kang W, Eldfjell Y, Fromm B, ..., Biryukova I, Friedländer MR
Genome Biol. 19 (1) 213 [2018-12-04; online 2018-12-04]
Marc Friedländer SciLifeLab Fellow
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FZD5 is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs.
Wright SC, Cañizal MCA, Benkel T, ..., Schulte G, Hoffmann C
Sci Signal 11 (559) eaar5536 [2018-12-04; online 2018-12-04]
Jens Carlsson SciLifeLab Fellow
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Tumor suppressor PNRC1 blocks rRNA maturation by recruiting the decapping complex to the nucleolus.
Gaviraghi M, Vivori C, Pareja Sanchez Y, ..., Cittaro D, Tonon G
EMBO J. 37 (23) - [2018-12-03; online 2018-10-29]
SciLifeLab Fellow Vicent Pelechano
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Methanogens and Iron-Reducing Bacteria: the Overlooked Members of Mercury-Methylating Microbial Communities in Boreal Lakes.
Bravo AG, Peura S, Buck M, ..., Björn E, Bertilsson S
Applied and environmental microbiology 84 (23) - [2018-12-01; online 2018-11-15]
Sari Peura SciLifeLab Fellow
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Metaxa2 Database Builder: enabling taxonomic identification from metagenomic or metabarcoding data using any genetic marker.
Bengtsson-Palme J, Richardson RT, Meola M, ..., Hartmann M, Nilsson RH
Bioinformatics 34 (23) 4027-4033 [2018-12-01; online 2018-06-19]
DDLS Fellow Johan Bengtsson-Palme
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Multiscale patterns and drivers of arbuscular mycorrhizal fungal communities in the roots and root-associated soil of a wild perennial herb.
Rasmussen PU, Hugerth LW, Blanchet FG, ..., Lindahl BD, Tack AJM
New Phytol. 220 (4) 1248-1261 [2018-12-00; online 2018-03-24]
DDLS Fellow Luisa Hugerth
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HYPERPARAMETER OPTIMIZATION FOR APPROXIMATE BAYESIAN COMPUTATION
Singh P, Hellander A
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Prashant Singh SciLifeLab Fellow
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Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer.
Gotthardt M, Eizirik DL, Aanstoot HJ, ..., Cnop M, Brom M
Diabetologia 61 (12) 2516-2519 [2018-12-00; online 2018-10-03]
Olof Eriksson SciLifeLab Fellow
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Cost-effective generation of precise label-free quantitative proteomes in high-throughput by microLC and data-independent acquisition
Vowinckel J, Zelezniak A, Bruderer R, ..., Reiter L, Ralser M
Sci Rep 8 (1) - [2018-12-00; online 2018-03-12]
Affiliated researcher Aleksej Zelezniak SciLifeLab Fellow
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Control of hepatic gluconeogenesis by Argonaute2.
Yan X, Wang Z, Bishop CA, ..., Willnow TE, Poy MN
Mol Metab 18 (-) 15-24 [2018-12-00; online 2018-10-09]
Marc Friedländer SciLifeLab Fellow
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Bridging gaps in transposable element research with single-molecule and single-cell technologies
Kutter C, Jern P, Suh A
Mobile DNA 9 (1) - [2018-12-00; online 2018-12-06]
Claudia Kutter SciLifeLab Fellow
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RollFISH achieves robust quantification of single-molecule RNA biomarkers in paraffin-embedded tumor tissue samples.
Wu C, Simonetti M, Rossell C, ..., Crosetto N, Nilsson M
Commun Biol 1 (1) 209 [2018-11-28; online 2018-11-28]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice.
Håversen L, Sundelin JP, Mardinoglu A, ..., Levin M, Borén J
Sci Rep 8 (1) 16973 [2018-11-19; online 2018-11-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Methanomethylophilus alvus Mx1201 Provides Basis for Mutual Orthogonal Pyrrolysyl tRNA/Aminoacyl-tRNA Synthetase Pairs in Mammalian Cells.
Meineke B, Heimgärtner J, Lafranchi L, Elsässer SJ
ACS chemical biology 13 (11) 3087-3096 [2018-11-16; online 2018-10-12]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
PREQUAL: detecting non-homologous characters in sets of unaligned homologous sequences.
Whelan S, Irisarri I, Burki F
Bioinformatics 34 (22) 3929-3930 [2018-11-15; online 2018-06-06]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Structural Characterization of Agonist Binding to Protease-Activated Receptor 2 through Mutagenesis and Computational Modeling.
Kennedy AJ, Ballante F, Johansson JR, ..., Nordqvist A, Carlsson J
ACS pharmacology & translational science 1 (2) 119-133 [2018-11-09; online 2018-10-16]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
A Network-Based Cancer Drug Discovery: From Integrated Multi-Omics Approaches to Precision Medicine.
Turanli B, Karagoz K, Gulfidan G, ..., Mardinoglu A, Arga KY
Curr. Pharm. Des. 24 (32) 3778-3790 [2018-11-07; online 2018-11-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Forces drive basement membrane invasion in Caenorhabditis elegans.
Cáceres R, Bojanala N, Kelley LC, ..., Sherwood DR, Plastino J
Proc. Natl. Acad. Sci. U.S.A. 115 (45) 11537-11542 [2018-11-06; online 2018-10-22]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon.
Sahlin K, Tomaszkiewicz M, Makova KD, Medvedev P
Nat Commun 9 (1) 4601 [2018-11-02; online 2018-11-02]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function.
Langlet F, Tarbier M, Haeusler RA, ..., Friedländer MR, Accili D
Mol Metab 17 (-) 49-60 [2018-11-00; online 2018-08-11]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Uncovering the regional localization of inhaled salmeterol retention in the lung.
Bäckström E, Hamm G, Nilsson A, ..., Goodwin RJA, Fridén M
Drug Deliv 25 (1) 838-845 [2018-11-00; online 2018-03-29]
Affiliated researcher
PubMed DOI Crossref
Transfection of crayfish hematopoietic tissue cells.
Shi H, Ruan L, Söderhäll I, Söderhäll K, Xu X
Dev. Comp. Immunol. 88 (-) 70-76 [2018-11-00; online 2018-07-09]
Affiliated researcher
DOI Crossref
QCM mass underestimation in molecular biotechnology: Proximity ligation assay for norovirus detection as a case study
Neumann F, Madaboosi N, Hernández-Neuta I, ..., Mecea V, Nilsson M
Sensors and Actuators B: Chemical 273 (-) 742-750 [2018-11-00; online 2018-11-00]
Affiliated researcher
PubMed DOI Crossref
How to minimize dye-induced perturbations while studying biomembrane structure and dynamics: PEG linkers as a rational alternative.
Mobarak E, Javanainen M, Kulig W, ..., Rog T, Vattulainen I
Biochim Biophys Acta Biomembr 1860 (11) 2436-2445 [2018-11-00; online 2018-07-18]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Gene-environment interaction of monoamine oxidase A in relation to antisocial behaviour: current and future directions.
Nilsson KW, Åslund C, Comasco E, Oreland L
J Neural Transm (Vienna) 125 (11) 1601-1626 [2018-11-00; online 2018-06-07]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Ribosome Profiling of Synechocystis Reveals Altered Ribosome Allocation at Carbon Starvation
Karlsen J, Asplund-Samuelsson J, Thomas Q, Jahn M, Hudson EP
mSystems 3 (5) - [2018-10-30; online 2018-10-30]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Detection of post-translational modifications using solid-phase proximity ligation assay.
Oliveira FMS, Mereiter S, Lönn P, ..., Reis CA, Kamali-Moghaddam M
N Biotechnol 45 (-) 51-59 [2018-10-25; online 2017-10-31]
Affiliated researcher
PubMed DOI Crossref
Combination of phage and Gram-positive bacterial display of human antibody repertoires enables isolation of functional high affinity binders.
Hu FJ, Volk AL, Persson H, ..., Uhlen M, Rockberg J
N Biotechnol 45 (-) 80-88 [2018-10-25; online 2017-08-01]
Affiliated researcher
PubMed DOI Crossref
A myopic perspective on the future of protein diagnostics.
Landegren U, Al-Amin RA, Björkesten J
N Biotechnol 45 (-) 14-18 [2018-10-25; online 2018-01-05]
Affiliated researcher
PubMed DOI Crossref
Chemoselective Probe Containing a Unique Bioorthogonal Cleavage Site for Investigation of Gut Microbiota Metabolism.
Garg N, Conway LP, Ballet C, ..., Löhr JM, Globisch D
Angew. Chem. Int. Ed. Engl. 57 (42) 13805-13809 [2018-10-15; online 2018-09-20]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Noninvasive Urine Biomarker Lateral Flow Immunoassay for Monitoring Active Onchocerciasis.
Shirey RJ, Globisch D, Eubanks LM, Hixon MS, Janda KD
ACS Infect Dis 4 (10) 1423-1431 [2018-10-12; online 2018-09-21]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Quantifying point-mutations in shotgun metagenomic data
Magesh S, Jonsson V, Bengtsson-Palme J
bioRxiv preprint - (-) - [2018-10-11; online 2018-10-11]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Growth of Cyanobacteria Is Constrained by the Abundance of Light and Carbon Assimilation Proteins.
Jahn M, Vialas V, Karlsen J, ..., Käll L, Hudson EP
Cell Reports 25 (2) 478-486.e8 [2018-10-09; online 2018-10-12]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Rapid Isolation of the Mitoribosome from HEK Cells.
Aibara S, Andréll J, Singh V, Amunts A
J Vis Exp - (140) - [2018-10-04; online 2018-10-04]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Conceptual and empirical advances in Neotropical biodiversity research.
Antonelli A, Ariza M, Albert J, ..., Zizka A, Edwards SV
PeerJ 6 (-) e5644 [2018-10-04; online 2018-10-04]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Reconstitution of immune cell interactions in free-standing membranes.
Jenkins E, Santos AM, O'Brien-Ball C, ..., Eggeling C, Sezgin E
J. Cell. Sci. 132 (4) - [2018-10-02; online 2018-10-02]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Bacteriophages Synergize with the Gut Microbial Community To Combat Salmonella.
Hu YOO, Hugerth LW, Bengtsson C, ..., Du J, Engstrand L
mSystems 3 (5) - [2018-10-02; online 2018-10-02]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA.
Delemotte L
J. Gen. Physiol. 150 (10) 1356-1359 [2018-10-01; online 2018-08-24]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Determining the molecular basis of voltage sensitivity in membrane proteins.
Kasimova MA, Lindahl E, Delemotte L
J. Gen. Physiol. 150 (10) 1444-1458 [2018-10-01; online 2018-08-27]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
High Cell Density Perfusion Culture has a Maintained Exoproteome and Metabolome.
Zamani L, Lundqvist M, Zhang Y, ..., Rockberg J, Chotteau V
Biotechnol J 13 (10) e1800036 [2018-10-00; online 2018-07-13]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide binding of transcription factor ZEB1 in triple-negative breast cancer cells.
Maturi V, Enroth S, Heldin CH, Moustakas A
J. Cell. Physiol. 233 (10) 7113-7127 [2018-10-00; online 2018-05-10]
Affiliated researcher
PubMed DOI Crossref
Genomes from uncultivated prokaryotes: a comparison of metagenome-assembled and single-amplified genomes.
Alneberg J, Karlsson CMG, Divne AM, ..., Andersson AF, Pinhassi J
Microbiome 6 (1) 173 [2018-09-28; online 2018-09-28]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
ESS: A Tool for Genome-Scale Quantification of Essentiality Score for Reaction/Genes in Constraint-Based Modeling.
Zhang C, Bidkhori G, Benfeitas R, ..., Uhlén M, Mardinoglu A
Front. Physiol. 9 (-) 1355 [2018-09-28; online 2018-09-28]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Bioanalytical advantages of a novel recombinant apyrase enzyme in ATP-based bioluminescence methods.
Pavankumar AR, Zelenin S, Lundin A, ..., Achour A, Russom A
Anal. Chim. Acta 1025 (-) 118-123 [2018-09-26; online 2018-04-26]
Affiliated researcher
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Maternal gut and breast milk microbiota affect infant gut antibiotic resistome and mobile genetic elements.
Pärnänen K, Karkman A, Hultman J, ..., Satokari R, Virta M
Nat Commun 9 (1) 3891 [2018-09-24; online 2018-09-24]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome.
Lovric A, Granér M, Bjornson E, ..., Mardinoglu A, Boren J
Sci Rep 8 (1) 14200 [2018-09-21; online 2018-09-21]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Meta-Analysis of Adiponectin as a Biomarker for the Detection of Metabolic Syndrome.
Liu Z, Liang S, Que S, ..., Zheng S, Mardinoglu A
Front. Physiol. 9 (-) 1238 [2018-09-19; online 2018-09-19]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Phylogeny and Systematics of Kewa (Kewaceae)
Thulin M, Larsson A, Edwards EJ, Moore AJ
Systematic Botany 43 (3) 689-700 [2018-09-10; online 2018-09-10]
Affiliated researcher
PubMed DOI Crossref
Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells.
Srpan K, Ambrose A, Karampatzakis A, ..., Önfelt B, Davis DM
J. Cell Biol. 217 (9) 3267-3283 [2018-09-03; online 2018-07-02]
Affiliated researcher
PubMed DOI Crossref
Promoter Usage and Dynamics in Vascular Smooth Muscle Cells Exposed to Fibroblast Growth Factor-2 or Interleukin-1β.
Alhendi AMN, Patrikakis M, Daub CO, ..., Arner E, Khachigian LM
Sci Rep 8 (1) 13164 [2018-09-03; online 2018-09-03]
Affiliated researcher
PubMed DOI Crossref
Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain.
Bazov I, Sarkisyan D, Kononenko O, ..., Yakovleva T, Bakalkin G
Cereb. Cortex 28 (9) 3129-3142 [2018-09-01; online 2017-10-03]
Affiliated researcher
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The pro-inflammatory role of platelets in cancer.
Olsson AK, Cedervall J
Platelets 29 (6) 569-573 [2018-09-00; online 2018-03-27]
Affiliated researcher
PubMed DOI Crossref
The downfall of TBA-354 - a possible explanation for its neurotoxicity via mass spectrometric imaging.
Ntshangase S, Shobo A, Kruger HG, ..., Govender T, Baijnath S
Xenobiotica 48 (9) 938-944 [2018-09-00; online 2017-10-13]
Affiliated researcher
PubMed DOI Crossref
The Protozoan Parasite Toxoplasma gondii Selectively Reprograms the Host Cell Translatome.
Leroux LP, Lorent J, Graber TE, ..., Larsson O, Jaramillo M
Infect. Immun. 86 (9) - [2018-09-00; online 2018-08-22]
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Targeting ATR in cancer.
Lecona E, Fernandez-Capetillo O
Nat. Rev. Cancer 18 (9) 586-595 [2018-09-00; online 2018-06-15]
Affiliated researcher
PubMed DOI Crossref
Systematic overexpression study to find target enzymes enhancing production of terpenes in Synechocystis PCC 6803, using isoprene as a model compound.
Englund E, Shabestary K, Hudson EP, Lindberg P
Metab. Eng. 49 (-) 164-177 [2018-09-00; online 2018-07-17]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Survival of Campylobacter jejuni and Campylobacter coli water isolates in lake and well water.
Nilsson A, Johansson C, Skarp A, ..., Bertilsson S, Rautelin H
APMIS 126 (9) 762-770 [2018-09-00; online 2018-08-31]
Affiliated researcher
PubMed DOI Crossref
Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer.
Bruun J, Sveen A, Barros R, ..., Almeida R, Lothe RA
Mol Oncol 12 (9) 1639-1655 [2018-09-00; online 2018-08-15]
Affiliated researcher
PubMed DOI Crossref
Multi-ethnic genome-wide association study for atrial fibrillation.
Roselli C, Chaffin MD, Weng LC, ..., Lunetta KL, Ellinor PT
Nat. Genet. 50 (9) 1225-1233 [2018-09-00; online 2018-06-11]
Affiliated researcher
PubMed DOI Crossref
Mechanisms for stalled replication fork stabilization: new targets for synthetic lethality strategies in cancer treatments.
Liao H, Ji F, Helleday T, Ying S
EMBO Rep. 19 (9) - [2018-09-00; online 2018-08-13]
Affiliated researcher
PubMed DOI Crossref
Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes.
Ruhrmann S, Ewing E, Piket E, ..., Piehl F, Jagodic M
Mult. Scler. 24 (10) 1288-1300 [2018-09-00; online 2017-08-02]
Affiliated researcher
PubMed DOI Crossref
Germline variation in the oxidative DNA repair genes NUDT1 and OGG1 is not associated with hereditary colorectal cancer or polyposis.
Mur P, Jemth AS, Bevc L, ..., Helleday T, Valle L
Hum. Mutat. 39 (9) 1214-1225 [2018-09-00; online 2018-07-04]
Affiliated researcher
PubMed DOI Crossref
Developing reduced SNP assays from whole-genome sequence data to estimate introgression in an organism with complex genetic patterns, the Iberian honeybee ( Apis mellifera iberiensis).
Henriques D, Parejo M, Vignal A, ..., Webster MT, Pinto MA
Evol Appl 11 (8) 1270-1282 [2018-09-00; online 2018-03-30]
Affiliated researcher
PubMed DOI Crossref
Detailed analysis of HTT repeat elements in human blood using targeted amplification-free long-read sequencing.
Höijer I, Tsai YC, Clark TA, ..., Gyllensten U, Ameur A
Hum. Mutat. 39 (9) 1262-1272 [2018-09-00; online 2018-07-12]
Affiliated researcher
PubMed DOI Crossref
Characterization of a cold-active transglutaminase from a crayfish, Pacifastacus leniusculus.
Sirikharin R, Söderhäll I, Söderhäll K
Fish Shellfish Immunol. 80 (-) 546-549 [2018-09-00; online 2018-06-27]
Affiliated researcher
PubMed DOI Crossref
Autoantibody profiling reveals four protein candidate autoantigens associated with systemic lupus erythematosus.
Frostegård J, Hellström C, Nilsson P, Frostegård AG, Ajeganova S
Lupus 27 (10) 1670-1678 [2018-09-00; online 2018-07-24]
Affiliated researcher
PubMed DOI Crossref
Assessment modalities of non-ionizing three-dimensional images for the quantification of facial morphology, symmetry, and appearance in cleft lip and palate: a systematic review.
Thierens LAM, De Roo NMC, De Pauw GAM, Brusselaers N
Int J Oral Maxillofac Surg 47 (9) 1095-1105 [2018-09-00; online 2018-06-05]
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An update on the role of type I interferons in systemic lupus erythematosus and Sjögren's syndrome.
Thorlacius GE, Wahren-Herlenius M, Rönnblom L
Curr Opin Rheumatol 30 (5) 471-481 [2018-09-00; online 2018-06-12]
Affiliated researcher
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A fine-needle aspiration-based protein signature discriminates benign from malignant breast lesions.
Franzén B, Kamali-Moghaddam M, Alexeyenko A, ..., Landegren U, Lewensohn R
Mol Oncol 12 (9) 1415-1428 [2018-09-00; online 2018-08-09]
Affiliated researcher
DOI Crossref
Top-Down Fabricated Silicon Nanowire Arrays for Field-Effect Detection of Prostate-Specific Antigen
Rani D, Pachauri V, Madaboosi N, ..., Conde JP, Ingebrandt S
ACS Omega 3 (8) 8471-8482 [2018-08-31; online 2018-08-00]
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PubMed DOI Crossref
Ca2+-binding protein NECAB2 facilitates inflammatory pain hypersensitivity.
Zhang MD, Su J, Adori C, ..., Harkany T, Hökfelt T
J. Clin. Invest. 128 (9) 3757-3768 [2018-08-31; online 2018-07-30]
Affiliated researcher
PubMed DOI Crossref
Mapping the Interface of a GPCR Dimer: A Structural Model of the A2A Adenosine and D2 Dopamine Receptor Heteromer.
Borroto-Escuela DO, Rodriguez D, Romero-Fernandez W, ..., Fuxe K, Carlsson J
Front. Pharmacol. 9 (-) 829 [2018-08-30; online 2018-08-30]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Eleven percent intact PGM3 in a severely immunodeficient patient with a novel splice-site mutation, a case report.
Lundin KE, Wang Q, Hamasy A, ..., Ekwall O, Smith CIE
BMC Pediatr 18 (1) 285 [2018-08-29; online 2018-08-29]
Affiliated researcher
PubMed DOI Crossref
Building of neomycin-nucleobase-amino acid conjugates for the inhibition of oncogenic miRNAs biogenesis.
Vo DD, Becquart C, Tran TPA, ..., Staedel C, Duca M
Org. Biomol. Chem. 16 (34) 6262-6274 [2018-08-29; online 2018-08-18]
Affiliated researcher
PubMed DOI Crossref
Statistical Analysis of Scanning Fluorescence Correlation Spectroscopy Data Differentiates Free from Hindered Diffusion.
Schneider F, Waithe D, Lagerholm BC, ..., Eggeling C, Fritzsche M
ACS Nano 12 (8) 8540-8546 [2018-08-28; online 2018-07-26]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment.
Dyczynski M, Vesterlund M, Björklund AC, ..., Tamm KP, Nilsson R
Cell Death Dis 9 (9) 846 [2018-08-28; online 2018-08-28]
Affiliated researcher
DOI Crossref
Direct observation of rotation-coupled protein diffusion along DNA on the microsecond timescale
Marklund E, Amselem E, Kipper K, ..., Deindl S, Elf J
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SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
A Protein-Based Encapsulation System with Calcium-Controlled Cargo Loading and Detachment.
Lizatović R, Assent M, Barendregt A, ..., Wennmalm S, André I
Angew. Chem. Int. Ed. Engl. 57 (35) 11334-11338 [2018-08-27; online 2018-07-30]
Affiliated researcher
PubMed DOI Crossref
Association of tamoxifen resistance and lipid reprogramming in breast cancer.
Hultsch S, Kankainen M, Paavolainen L, ..., Pietiäinen V, Kallioniemi O
BMC Cancer 18 (1) 850 [2018-08-24; online 2018-08-24]
Affiliated researcher
PubMed DOI Crossref
Stereotypic Immune System Development in Newborn Children.
Olin A, Henckel E, Chen Y, ..., Bohlin K, Brodin P
Cell 174 (5) 1277-1292.e14 [2018-08-23; online 2018-08-25]
Affiliated researcher
PubMed DOI Crossref
Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development.
Marques S, van Bruggen D, Vanichkina DP, ..., Taft RJ, Castelo-Branco G
Dev. Cell 46 (4) 504-517.e7 [2018-08-20; online 2018-08-02]
Affiliated researcher
DOI Crossref
Sulfonimidamides: Synthesis and Applications in Preparative Organic Chemistry
Nandi GC, Arvidsson PI
Adv. Synth. Catal. 360 (16) 2976-3001 [2018-08-17; online 2018-05-25]
Affiliated researcher
PubMed DOI Crossref
Role of Gln222 in Photoswitching of Aequorea Fluorescent Proteins: A Twisting and H-Bonding Affair?
Storti B, Margheritis E, Abbandonato G, ..., Nifosì R, Bizzarri R
ACS chemical biology 13 (8) 2082-2093 [2018-08-17; online 2018-06-19]
Affiliated researcher Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Enhanced photon collection enables four dimensional fluorescence nanoscopy of living systems.
Masullo LA, Bodén A, Pennacchietti F, ..., Ratz M, Testa I
Nat Commun 9 (1) 3281 [2018-08-16; online 2018-08-16]
Affiliated researcher Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
The binding of Chp2's chromodomain to methylated H3K9 is essential for Chp2's role in heterochromatin assembly in fission yeast.
Maksimov V, Oya E, Tanaka M, ..., Bjerling P, Nakayama JI
PLoS ONE 13 (8) e0201101 [2018-08-15; online 2018-08-15]
Affiliated researcher
PubMed DOI Crossref
Surface Display of Small Affinity Proteins on Synechocystis sp. Strain PCC 6803 Mediated by Fusion to the Major Type IV Pilin PilA1.
Cengic I, Uhlén M, Hudson EP
J. Bacteriol. 200 (16) - [2018-08-15; online 2018-07-25]
Affiliated researcher Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Characterization of avian influenza virus attachment patterns to human and pig tissues.
Eriksson P, Lindskog C, Engholm E, ..., Jourdain E, Ellström P
Sci Rep 8 (1) 12215 [2018-08-15; online 2018-08-15]
Affiliated researcher
DOI Crossref
A Decomposition Method for Global Evaluation of Shannon Entropy and Local Estimations of Algorithmic Complexity
Zenil H, Hernández-Orozco S, Kiani N, ..., Rueda-Toicen A, Tegnér J
Entropy 20 (8) 605 [2018-08-15; online 2018-08-15]
Affiliated researcher
PubMed DOI Crossref
Novel Autotrophic Organisms Contribute Significantly to the Internal Carbon Cycling Potential of a Boreal Lake.
Peura S, Buck M, Aalto SL, ..., Nykänen H, Eiler A
MBio 9 (4) - [2018-08-14; online 2018-08-14]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Predicting drug permeability through skin using molecular dynamics simulation.
Lundborg M, Wennberg CL, Narangifard A, Lindahl E, Norlén L
J Control Release 283 (-) 269-279 [2018-08-10; online 2018-06-01]
Affiliated researcher
PubMed DOI Crossref
Stationary and portable sequencing-based approaches for tracing wastewater contamination in urban stormwater systems.
Hu YOO, Ndegwa N, Alneberg J, ..., Fagerberg J, Andersson AF
Sci Rep 8 (1) 11907 [2018-08-09; online 2018-08-09]
Affiliated researcher
PubMed DOI Crossref
SURGE complex of Plasmodium falciparum in the rhoptry-neck (SURFIN4.2-RON4-GLURP) contributes to merozoite invasion.
Quintana MDP, Ch'ng JH, Zandian A, ..., Chan S, Wahlgren M
PLoS ONE 13 (8) e0201669 [2018-08-09; online 2018-08-09]
Affiliated researcher
PubMed DOI Crossref
Proteomic Biomarkers for Incident Aortic Stenosis Requiring Valvular Replacement.
Ljungberg J, Janiec M, Bergdahl IA, ..., Fall T, Söderberg S
Circulation 138 (6) 590-599 [2018-08-07; online 2018-03-01]
Affiliated researcher
PubMed DOI Crossref
New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites.
Ballet C, Correia MSP, Conway LP, ..., Löhr JM, Globisch D
Chem Sci 9 (29) 6233-6239 [2018-08-07; online 2018-06-28]
Affiliated researcher Daniel Globisch SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Evaluation of the Therapeutic Potential of a HER3-Binding Affibody Construct TAM-HER3 in Comparison with a Monoclonal Antibody, Seribantumab.
Orlova A, Bass TZ, Rinne SS, ..., Tolmachev V, Ståhl S
Mol. Pharm. 15 (8) 3394-3403 [2018-08-06; online 2018-07-25]
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Mitochondrial genomes reveal an east to west cline of steppe ancestry in Corded Ware populations.
Juras A, Chyleński M, Ehler E, ..., Jakobsson M, Kośko A
Sci Rep 8 (1) 11603 [2018-08-02; online 2018-08-02]
Affiliated researcher
PubMed DOI Crossref
A colorimetric assay to rapidly determine the activities of lytic polysaccharide monooxygenases.
Wang D, Li J, Wong ACY, Aachmann FL, Hsieh YSY
Biotechnol Biofuels 11 (-) 215 [2018-08-02; online 2018-08-02]
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Sulfonyl Fluorides (SFs): More Than Click Reagents?
Chinthakindi PK, Arvidsson PI
Eur. J. Org. Chem. 2018 (27-28) 3648-3666 [2018-08-01; online 2018-07-06]
Affiliated researcher
PubMed DOI Crossref
Investigation of viable taxa in the deep terrestrial biosphere suggests high rates of nutrient recycling.
Lopez-Fernandez M, Broman E, Turner S, ..., Bertilsson S, Dopson M
FEMS Microbiol. Ecol. 94 (8) - [2018-08-01; online 2018-06-23]
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PubMed DOI Crossref
Evolution of the growth hormone, prolactin, prolactin 2 and somatolactin family.
Ocampo Daza D, Larhammar D
Gen. Comp. Endocrinol. 264 (-) 94-112 [2018-08-01; online 2018-01-12]
Affiliated researcher
PubMed DOI Crossref
Different menopausal hormone regimens and risk of breast cancer.
Brusselaers N, Tamimi RM, Konings P, ..., Adami HO, Lagergren J
Ann. Oncol. 29 (8) 1771-1776 [2018-08-01; online 2018-06-20]
Affiliated researcher
PubMed DOI Crossref
CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis.
Lugano R, Vemuri K, Yu D, ..., Dejana E, Dimberg A
J. Clin. Invest. 128 (8) 3280-3297 [2018-08-01; online 2018-06-25]
Affiliated researcher
PubMed DOI Crossref
An imidazole based H-Phe-Phe-NH 2 peptidomimetic with anti-allodynic effect in spared nerve injury mice.
Skogh A, Lesniak A, Sköld C, ..., Hallberg M, Sandström A
Bioorg. Med. Chem. Lett. 28 (14) 2446-2450 [2018-08-01; online 2018-06-15]
Affiliated researcher
PubMed DOI Crossref
The environmental neurotoxin β-N-methylamino-L-alanine inhibits melatonin synthesis in primary pinealocytes and a rat model.
Pierozan P, Andersson M, Brandt I, Karlsson O
Journal of pineal research 65 (1) e12488 [2018-08-00; online 2018-04-06]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
The PDGF/PDGFR pathway as a drug target.
Papadopoulos N, Lennartsson J
Mol. Aspects Med. 62 (-) 75-88 [2018-08-00; online 2017-11-15]
Affiliated researcher
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Structure and function of the global topsoil microbiome.
Bahram M, Hildebrand F, Forslund SK, ..., Tedersoo L, Bork P
Nature 560 (7717) 233-237 [2018-08-00; online 2018-08-01]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Scavenging of superoxide by a membrane-bound superoxide oxidase.
Lundgren CAK, Sjöstrand D, Biner O, ..., von Ballmoos C, Högbom M
Nat. Chem. Biol. 14 (8) 788-793 [2018-08-00; online 2018-06-18]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Role of proteoglycans in neuro-inflammation and central nervous system fibrosis.
Heindryckx F, Li JP
Matrix Biol. 68-69 (-) 589-601 [2018-08-00; online 2018-01-31]
Affiliated researcher
PubMed DOI Crossref
RNA velocity of single cells.
La Manno G, Soldatov R, Zeisel A, ..., Linnarsson S, Kharchenko PV
Nature 560 (7719) 494-498 [2018-08-00; online 2018-08-08]
Affiliated researcher
PubMed DOI Crossref
Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains.
Ju CH, Blum LK, Kongpachith S, ..., Davis MM, Robinson WH
Clin. Immunol. 193 (-) 70-79 [2018-08-00; online 2018-02-02]
Affiliated researcher
PubMed DOI Crossref
Plasma Protein Profiling Reveal Osteoprotegerin as a Marker of Prognostic Impact for Colorectal Cancer.
Birgisson H, Tsimogiannis K, Freyhult E, Kamali-Moghaddam M
Transl Oncol 11 (4) 1034-1043 [2018-08-00; online 2018-07-04]
Affiliated researcher
PubMed DOI Crossref
Modulation of TGFβ/Smad signaling by the small GTPase RhoB.
Livitsanou M, Vasilaki E, Stournaras C, Kardassis D
Cell. Signal. 48 (-) 54-63 [2018-08-00; online 2018-04-26]
Affiliated researcher
PubMed DOI Crossref
Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint.
Pieper J, Dubnovitsky A, Gerstner C, ..., Achour A, Malmström V
J. Autoimmun. 92 (-) 47-56 [2018-08-00; online 2018-05-28]
Affiliated researcher
PubMed DOI Crossref
Longitudinal changes in persistent organic pollutants (POPs) from 2001 to 2009 in a sample of elderly Swedish men and women.
Stubleski J, Lind L, Salihovic S, Lind PM, Kärrman A
Environ. Res. 165 (-) 193-200 [2018-08-00; online 2018-04-30]
Affiliated researcher
DOI Crossref
Interspecific variation in ploidy as a key plant trait outlining local extinction risks and community patterns in fragmented landscapes
Plue J, Kimberley A, Slotte T
Funct Ecol 32 (8) 2095-2106 [2018-08-00; online 2018-05-22]
Affiliated researcher SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Human skin barrier structure and function analyzed by cryo-EM and molecular dynamics simulation.
Lundborg M, Narangifard A, Wennberg CL, ..., Daneholt B, Norlén L
J. Struct. Biol. 203 (2) 149-161 [2018-08-00; online 2018-04-24]
Affiliated researcher
PubMed DOI Crossref
Fast reversibly photoswitching red fluorescent proteins for live-cell RESOLFT nanoscopy.
Pennacchietti F, Serebrovskaya EO, Faro AR, ..., Mishin AS, Testa I
Nat. Methods 15 (8) 601-604 [2018-08-00; online 2018-07-09]
Affiliated researcher Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Ether cross-link formation in the R2-like ligand-binding oxidase.
Griese JJ, Branca RMM, Srinivas V, Högbom M
J. Biol. Inorg. Chem. 23 (6) 879-886 [2018-08-00; online 2018-06-26]
Affiliated researcher
PubMed DOI Crossref
Epigenetics in pediatric acute lymphoblastic leukemia.
Nordlund J, Syvänen AC
Semin. Cancer Biol. 51 (-) 129-138 [2018-08-00; online 2017-09-05]
Affiliated researcher
PubMed DOI Crossref
Epigenetics in multiple myeloma: From mechanisms to therapy.
Alzrigat M, Párraga AA, Jernberg-Wiklund H
Semin. Cancer Biol. 51 (-) 101-115 [2018-08-00; online 2017-09-27]
Affiliated researcher
PubMed DOI Crossref
Epigenetic deregulation in chronic lymphocytic leukemia: Clinical and biological impact.
Mansouri L, Wierzbinska JA, Plass C, Rosenquist R
Semin. Cancer Biol. 51 (-) 1-11 [2018-08-00; online 2018-02-07]
Affiliated researcher
PubMed DOI Crossref
Disruption of A2AR-D2R Heteroreceptor Complexes After A2AR Transmembrane 5 Peptide Administration Enhances Cocaine Self-Administration in Rats.
Borroto-Escuela DO, Wydra K, Li X, ..., Filip M, Fuxe K
Mol. Neurobiol. 55 (8) 7038-7048 [2018-08-00; online 2018-01-30]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
De novo KCNA1 variants in the PVP motif cause infantile epileptic encephalopathy and cognitive impairment similar to recurrent KCNA2 variants.
Rogers A, Golumbek P, Cellini E, ..., Thuresson AC, Gurnett CA
Am. J. Med. Genet. A 176 (8) 1748-1752 [2018-08-00; online 2018-07-28]
Affiliated researcher
PubMed DOI Crossref
Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance.
Larsson DGJ, Andremont A, Bengtsson-Palme J, ..., Wellington EM, Wernersson AS
Environ Int 117 (-) 132-138 [2018-08-00; online 2018-05-07]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Consensus guidelines for the use and interpretation of angiogenesis assays.
Nowak-Sliwinska P, Alitalo K, Allen E, ..., Yoder MC, Griffioen AW
Angiogenesis 21 (3) 425-532 [2018-08-00; online 2018-05-17]
Affiliated researcher
PubMed DOI Crossref
Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis.
Kowalec K, Wright GEB, Drögemöller BI, ..., Tremlett H, Carleton BC
Nat. Genet. 50 (8) 1081-1085 [2018-08-00; online 2018-07-16]
Affiliated researcher
PubMed DOI Crossref
Characterization of Swedish Campylobacter coli clade 2 and clade 3 water isolates.
Nilsson A, Skarp A, Johansson C, ..., Engstrand L, Rautelin H
Microbiologyopen 7 (4) e00583 [2018-08-00; online 2018-02-09]
Affiliated researcher
PubMed DOI Crossref
Changing the site energy of per-614 in the Peridinin-chlorophyll a-protein does not alter its capability of chlorophyll triplet quenching.
Agostini A, Niklas J, Schulte T, ..., Lubitz W, Carbonera D
Biochim Biophys Acta Bioenerg 1859 (8) 612-618 [2018-08-00; online 2018-05-19]
Affiliated researcher
PubMed DOI Crossref
Changes in markers of liver function in relation to changes in perfluoroalkyl substances - A longitudinal study.
Salihovic S, Stubleski J, Kärrman A, ..., Lind L, Lind PM
Environ Int 117 (-) 196-203 [2018-08-00; online 2018-05-10]
Affiliated researcher
PubMed DOI Crossref
Algorithmically probable mutations reproduce aspects of evolution, such as convergence rate, genetic memory and modularity.
Hernández-Orozco S, Kiani NA, Zenil H
R Soc Open Sci 5 (8) 180399 [2018-08-00; online 2018-08-29]
Affiliated researcher
PubMed DOI Crossref
Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans.
Cedernaes J, Schönke M, Westholm JO, ..., Zierath JR, Benedict C
Sci Adv 4 (8) eaar8590 [2018-08-00; online 2018-08-22]
Affiliated researcher
PubMed DOI Crossref
The microbial metabolite trimethylamine-N-oxide in association with inflammation and microbial dysregulation in three HIV cohorts at various disease stages.
Missailidis C, Neogi U, Stenvinkel P, ..., Nowak P, Bergman P
AIDS 32 (12) 1589-1598 [2018-07-31; online 2018-04-06]
Affiliated researcher
PubMed DOI Crossref
The Tumor Suppressor MIG6 Controls Mitotic Progression and the G2/M DNA Damage Checkpoint by Stabilizing the WEE1 Kinase.
Sasaki M, Terabayashi T, Weiss SM, Ferby I
Cell Reports 24 (5) 1278-1289 [2018-07-31; online 2018-08-02]
Affiliated researcher
PubMed DOI Crossref
RAD Sequencing and a Hybrid Antarctic Fur Seal Genome Assembly Reveal Rapidly Decaying Linkage Disequilibrium, Global Population Structure and Evidence for Inbreeding.
Humble E, Dasmahapatra KK, Martinez-Barrio A, ..., Wolf JBW, Hoffman JI
G3 8 (8) 2709-2722 [2018-07-31; online 2018-07-31]
Affiliated researcher
PubMed DOI Crossref
BARM and BalticMicrobeDB, a reference metagenome and interface to meta-omic data for the Baltic Sea.
Alneberg J, Sundh J, Bennke C, ..., Labrenz M, Andersson AF
Sci Data 5 (-) 180146 [2018-07-31; online 2018-07-31]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
Switch-like PKA responses in the nucleus of striatal neurons.
Yapo C, Nair AG, Hellgren Kotaleski J, Vincent P, Castro LRV
J. Cell. Sci. 131 (14) - [2018-07-27; online 2018-07-27]
Affiliated researcher
PubMed DOI Crossref
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.
van Setten J, Brody JA, Jamshidi Y, ..., Arking DE, Sotoodehnia N
Nat Commun 9 (1) 2904 [2018-07-25; online 2018-07-25]
Affiliated researcher
PubMed DOI Crossref
Analysis of public RNA-sequencing data reveals biological consequences of genetic heterogeneity in cell line populations.
Fasterius E, Al-Khalili Szigyarto C
Sci Rep 8 (1) 11226 [2018-07-25; online 2018-07-25]
Affiliated researcher
DOI Crossref
A Review of Graph and Network Complexity from an Algorithmic Information Perspective
Zenil H, Kiani N, Tegnér J
Entropy 20 (8) 551 [2018-07-25; online 2018-07-25]
Affiliated researcher
PubMed DOI Crossref
Whole genome SNP-associated signatures of local adaptation in honeybees of the Iberian Peninsula.
Henriques D, Wallberg A, Chávez-Galarza J, ..., Webster MT, Pinto MA
Sci Rep 8 (1) 11145 [2018-07-24; online 2018-07-24]
Affiliated researcher
PubMed DOI Crossref
A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma.
Einarsdottir BO, Karlsson J, Söderberg EMV, ..., Helleday T, Nilsson JA
Cell Death Dis 9 (8) 810 [2018-07-24; online 2018-07-24]
Affiliated researcher
PubMed DOI Crossref
Targeted Repression of Essential Genes To Arrest Growth and Increase Carbon Partitioning and Biofuel Titers in Cyanobacteria.
Shabestary K, Anfelt J, Ljungqvist E, ..., Yao L, Hudson EP
ACS Synth. Biol. 7 (7) 1669-1675 [2018-07-20; online 2018-06-08]
Affiliated researcher Paul Hudson SciLifeLab Fellow
DOI Crossref
Symmetry and Correspondence of Algorithmic Complexity over Geometric, Spatial and Topological Representations
Zenil H, Kiani N, Tegnér J
Entropy 20 (7) 534 [2018-07-18; online 2018-07-18]
Affiliated researcher
PubMed DOI Crossref
Metabolic Network-Based Identification and Prioritization of Anticancer Targets Based on Expression Data in Hepatocellular Carcinoma.
Bidkhori G, Benfeitas R, Elmas E, ..., Nielsen J, Mardinoglu A
Front. Physiol. 9 (-) 916 [2018-07-17; online 2018-07-17]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome.
Sork H, Corso G, Krjutskov K, ..., Mäger I, El Andaloussi S
Sci Rep 8 (1) 10813 [2018-07-17; online 2018-07-17]
Affiliated researcher
PubMed DOI Crossref
Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events.
Honkura N, Richards M, Laviña B, ..., Betsholtz C, Claesson-Welsh L
Nat Commun 9 (1) 2746 [2018-07-16; online 2018-07-16]
Affiliated researcher
PubMed DOI Crossref
SECAPR-a bioinformatics pipeline for the rapid and user-friendly processing of targeted enriched Illumina sequences, from raw reads to alignments.
Andermann T, Cano Á, Zizka A, Bacon C, Antonelli A
PeerJ 6 (-) e5175 [2018-07-13; online 2018-07-13]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank.
Fall T, Gustafsson S, Orho-Melander M, Ingelsson E
Diabetologia - (-) - [2018-07-12; online 2018-07-12]
Affiliated researcher
PubMed DOI Crossref
Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A 2 Type X (sPLA2-X) Inhibitors.
Knerr L, Giordanetto F, Nordberg P, ..., Roth RG, Ahlqvist M
ACS Med. Chem. Lett. 9 (7) 594-599 [2018-07-12; online 2018-06-23]
Affiliated researcher
PubMed DOI Crossref
Design of Selective sPLA 2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid.
Giordanetto F, Knerr L, Nordberg P, ..., Jansen F, Ahlqvist M
ACS Med. Chem. Lett. 9 (7) 600-605 [2018-07-12; online 2018-06-23]
Affiliated researcher
PubMed DOI Crossref
Tamoxifen-Induced Apoptosis of MCF-7 Cells via GPR30/PI3K/MAPKs Interactions: Verification by ODE Modeling and RNA Sequencing.
Rouhimoghadam M, Safarian S, Carroll JS, Sheibani N, Bidkhori G
Front. Physiol. 9 (-) 907 [2018-07-11; online 2018-07-11]
Affiliated researcher
PubMed DOI Crossref
Nanoscale Spatiotemporal Diffusion Modes Measured by Simultaneous Confocal and Stimulated Emission Depletion Nanoscopy Imaging.
Schneider F, Waithe D, Galiani S, ..., Sezgin E, Eggeling C
Nano Lett. 18 (7) 4233-4240 [2018-07-11; online 2018-06-19]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Rare Copy Number Variants in Array-Based Comparative Genomic Hybridization in Early-Onset Skeletal Fragility.
Costantini A, Skarp S, Kämpe A, ..., Lindstrand A, Mäkitie O
Front Endocrinol (Lausanne) 9 (-) 380 [2018-07-10; online 2018-07-10]
Affiliated researcher
PubMed DOI Crossref
Rapid Phenotypic Antibiotic Susceptibility Testing of Uropathogens Using Optical Signal Analysis on the Nanowell Slide.
Veses-Garcia M, Antypas H, Löffler S, ..., Andersson-Svahn H, Richter-Dahlfors A
Front Microbiol 9 (-) 1530 [2018-07-10; online 2018-07-10]
Affiliated researcher
PubMed DOI Crossref
Changes in brain architecture are consistent with altered fear processing in domestic rabbits.
Brusini I, Carneiro M, Wang C, ..., Fredrikson M, Andersson L
Proc. Natl. Acad. Sci. U.S.A. 115 (28) 7380-7385 [2018-07-10; online 2018-06-25]
Affiliated researcher
PubMed DOI Crossref
Aβ under stress: the effects of acidosis, Cu 2+-binding, and oxidation on amyloid β-peptide dimers.
Liao Q, Owen MC, Bali S, Barz B, Strodel B
Chem. Commun. (Camb.) 54 (56) 7766-7769 [2018-07-10; online 2018-06-28]
Affiliated researcher
PubMed DOI Crossref
Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development.
Binder ZA, Thorne AH, Bakas S, ..., Furnari FB, O'Rourke DM
Cancer Cell 34 (1) 163-177.e7 [2018-07-09; online 2018-07-11]
Affiliated researcher
PubMed DOI Crossref
The diversity of uncharacterized antibiotic resistance genes can be predicted from known gene variants-but not always.
Bengtsson-Palme J
Microbiome 6 (1) 125 [2018-07-07; online 2018-07-07]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages.
Baskaran S, Mayrhofer M, Kultima HG, ..., Isaksson A, Nelander S
Neuro-oncology 20 (8) 1080-1091 [2018-07-05; online 2018-02-21]
Affiliated researcher
PubMed DOI Crossref
DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation.
Lemmens B, Hegarat N, Akopyan K, ..., Hochegger H, Lindqvist A
Mol. Cell 71 (1) 117-128.e3 [2018-07-05; online 2018-06-28]
Affiliated researcher
DOI Crossref
Morphological and genetic variation of Fucus in the eastern Gulf of Bothnia, northern Baltic Sea
Rinne H, Björkman U, Sjöqvist C, Salovius-Laurén S, Mattila J
European Journal of Phycology 53 (3) 369-380 [2018-07-03; online 2018-05-17]
Affiliated researcher
PubMed DOI Crossref
Changes in plasma levels of perfluoroalkyl substances (PFASs) are related to increase in carotid intima-media thickness over 10 years - a longitudinal study.
Lind PM, Salihovic S, Stubleski J, Kärrman A, Lind L
Environ Health 17 (1) 59 [2018-07-03; online 2018-07-03]
Affiliated researcher
PubMed DOI Crossref
3D Maps of Mineral Composition and Hydroxyapatite Orientation in Fossil Bone Samples Obtained by X-ray Diffraction Computed Tomography.
Mürer FK, Sanchez S, Álvarez-Murga M, ..., Bech M, Breiby DW
Sci Rep 8 (1) 10052 [2018-07-03; online 2018-07-03]
Affiliated researcher
PubMed DOI Crossref
Inhibition of integrin α Vβ6 changes fibril thickness of stromal collagen in experimental carcinomas.
Olof Olsson P, Gustafsson R, Salnikov AV, ..., Heldin NE, Rubin K
Cell Commun. Signal 16 (1) 36 [2018-07-02; online 2018-07-02]
Affiliated researcher
PubMed DOI Crossref
Human Immunodeficiency Virus-Infected Women Have High Numbers of CD103-CD8+ T Cells Residing Close to the Basal Membrane of the Ectocervical Epithelium.
Gibbs A, Buggert M, Edfeldt G, ..., Broliden K, Tjernlund A
J. Infect. Dis. 218 (3) 453-465 [2018-07-02; online 2017-12-23]
Affiliated researcher
PubMed DOI Crossref
EviNet: a web platform for network enrichment analysis with flexible definition of gene sets.
Jeggari A, Alekseenko Z, Petrov I, ..., Ericson J, Alexeyenko A
Nucleic Acids Res. 46 (W1) W163-W170 [2018-07-02; online 2018-06-13]
Affiliated researcher
PubMed DOI Crossref
SETD2 Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma.
Sakthikumar S, Elvers I, Kim J, ..., Marinescu VD, Lindblad-Toh K
Cancer Res. 78 (13) 3421-3431 [2018-07-01; online 2018-05-03]
Affiliated researcher
PubMed DOI Crossref
Genome Evolution of Bartonellaceae Symbionts of Ants at the Opposite Ends of the Trophic Scale.
Bisch G, Neuvonen MM, Pierce NE, ..., Lukasik P, Andersson SGE
Genome Biol Evol 10 (7) 1687-1704 [2018-07-01; online 2018-07-10]
Affiliated researcher
PubMed DOI Crossref
Formation of Immune Complexes with a Tetanus-Derived B Cell Epitope Boosts Human T Cell Responses to Covalently Linked Peptides in an Ex Vivo Blood Loop System.
Fletcher EAK, van Maren W, Cordfunke R, ..., Drijfhout JW, Mangsbo SM
J. Immunol. 201 (1) 87-97 [2018-07-01; online 2018-05-11]
Affiliated researcher
PubMed DOI Crossref
A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate.
Riley AM, Unterlass J, Konieczny V, ..., Helleday T, Potter BVL
Med. Chem. Commun. 9 (7) 1105-1113 [2018-07-01; online 2018-06-04]
Affiliated researcher
PubMed DOI Crossref
Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus.
Carlsson PO, Espes D, Sedigh A, ..., Olerud J, Korsgren O
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 18 (7) 1735-1744 [2018-07-00; online 2018-02-02]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
The vaginal microbiome amplifies sex hormone-associated cyclic changes in cervicovaginal inflammation and epithelial barrier disruption.
Bradley F, Birse K, Hasselrot K, ..., Broliden K, Burgener AD
Am. J. Reprod. Immunol. 80 (1) e12863 [2018-07-00; online 2018-04-30]
Affiliated researcher
PubMed DOI Crossref
The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock.
Garre E, Pelechano V, Sánchez Del Pino M, Alepuz P, Sunnerhagen P
PLoS Genet 14 (7) e1007563 [2018-07-00; online 2018-07-30]
Affiliated researcher SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE.
Hagberg N, Joelsson M, Leonard D, ..., Bryceson YT, Rönnblom L
Ann. Rheum. Dis. 77 (7) 1070-1077 [2018-07-00; online 2018-02-23]
Affiliated researcher
PubMed DOI Crossref
Selective concentration for ciprofloxacin resistance in Escherichia coli grown in complex aquatic bacterial biofilms.
Kraupner N, Ebmeyer S, Bengtsson-Palme J, ..., Flach CF, Larsson DGJ
Environ Int 116 (-) 255-268 [2018-07-00; online 2018-04-25]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Oak genome reveals facets of long lifespan.
Plomion C, Aury JM, Amselem J, ..., Kremer A, Salse J
Nat Plants 4 (7) 440-452 [2018-07-00; online 2018-06-18]
Affiliated researcher
PubMed DOI Crossref
Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis.
Leonard D, Svenungsson E, Dahlqvist J, ..., Criswell LA, Rönnblom L
Ann. Rheum. Dis. 77 (7) 1063-1069 [2018-07-00; online 2018-03-07]
Affiliated researcher
PubMed DOI Crossref
Molecular allergen profiling in horses by microarray reveals Fag e 2 from buckwheat as a frequent sensitizer.
Einhorn L, Hofstetter G, Brandt S, ..., Pali-Schöll I, Jensen-Jarolim E
Allergy 73 (7) 1436-1446 [2018-07-00; online 2018-02-27]
Affiliated researcher
PubMed DOI Crossref
Mining the Human Tissue Proteome for Protein Citrullination.
Lee CY, Wang D, Wilhelm M, ..., Hahne H, Kuster B
Mol. Cell Proteomics 17 (7) 1378-1391 [2018-07-00; online 2018-04-02]
Affiliated researcher
DOI Crossref
Intra-droplet acoustic particle focusing: simulations and experimental observations
Fornell A, Garofalo F, Nilsson J, Bruus H, Tenje M
Microfluid Nanofluid 22 (7) - [2018-07-00; online 2018-06-28]
Affiliated researcher
PubMed DOI Crossref
Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling.
Hertzog J, Dias Junior AG, Rigby RE, ..., Kohl A, Rehwinkel J
Eur. J. Immunol. 48 (7) 1120-1136 [2018-07-00; online 2018-04-06]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML.
Brück O, Blom S, Dufva O, ..., Pellinen T, Mustjoki S
Leukemia 32 (7) 1643-1656 [2018-07-00; online 2018-06-20]
Affiliated researcher
PubMed DOI Crossref
Identification of inhibitors of Tartrate-resistant acid phosphatase (TRAP/ACP5) activity by small-molecule screening.
Reithmeier A, Lundbäck T, Haraldsson M, ..., Gustavsson AL, Andersson G
Chem Biol Drug Des 92 (1) 1255-1271 [2018-07-00; online 2018-03-30]
Affiliated researcher
PubMed DOI Crossref
High speed of fork progression induces DNA replication stress and genomic instability.
Maya-Mendoza A, Moudry P, Merchut-Maya JM, ..., Strauss R, Bartek J
Nature 559 (7713) 279-284 [2018-07-00; online 2018-06-27]
Affiliated researcher
DOI Crossref
Genome-wide expression analysis suggests a role for jasmonates in the resistance to blue mold in apple
Ahmadi-Afzadi M, Orsel M, Pelletier S, ..., Nybom H, Renou JP
Plant Growth Regul 85 (3) 375-387 [2018-07-00; online 2018-04-18]
Affiliated researcher
PubMed DOI Crossref
Four evolutionary trajectories underlie genetic intratumoral variation in childhood cancer.
Karlsson J, Valind A, Holmquist Mengelbier L, ..., Bexell D, Gisselsson D
Nat. Genet. 50 (7) 944-950 [2018-07-00; online 2018-06-04]
Affiliated researcher
PubMed DOI Crossref
Demographic expansion and genetic load of the halophyte model plant Eutrema salsugineum.
Wang XJ, Hu QJ, Guo XY, ..., Lascoux M, Liu JQ
Mol. Ecol. 27 (14) 2943-2955 [2018-07-00; online 2018-06-22]
Affiliated researcher
PubMed DOI Crossref
Childhood Bereavement and Lower Stress Resilience in Late Adolescence.
Kennedy B, Chen R, Valdimarsdóttir U, ..., Fang F, Fall K
J Adolesc Health 63 (1) 108-114 [2018-07-00; online 2018-04-30]
Affiliated researcher
PubMed DOI Crossref
Cannabinoid Type 1 Receptors Are Upregulated During Acute Activation of Brown Adipose Tissue.
Lahesmaa M, Eriksson O, Gnad T, ..., Virtanen KA, Nuutila P
Diabetes 67 (7) 1226-1236 [2018-07-00; online 2018-04-12]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Associations of monoamine oxidase A gene first exon methylation with sexual abuse and current depression in women.
Checknita D, Ekström TJ, Comasco E, ..., Tiihonen J, Hodgins S
J Neural Transm (Vienna) 125 (7) 1053-1064 [2018-07-00; online 2018-03-29]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Assessing uncertainties in x-ray single-particle three-dimensional reconstruction.
Liu J, Engblom S, Nettelblad C
Phys Rev E 98 (1-1) 013303 [2018-07-00; online 2018-08-17]
Affiliated researcher
PubMed DOI Crossref
An in vitro model of lissencephaly: expanding the role of DCX during neurogenesis.
Shahsavani M, Pronk RJ, Falk R, ..., Gage FH, Falk A
Mol. Psychiatry 23 (7) 1674-1684 [2018-07-00; online 2017-09-19]
Affiliated researcher
PubMed DOI Crossref
ADARs and editing: The role of A-to-I RNA modification in cancer progression.
Fritzell K, Xu LD, Lagergren J, Öhman M
Semin. Cell Dev. Biol. 79 (-) 123-130 [2018-07-00; online 2017-11-16]
Affiliated researcher
PubMed DOI Crossref
A protein activity assay to measure global transcription factor activity reveals determinants of chromatin accessibility.
Wei B, Jolma A, Sahu B, ..., Taipale M, Taipale J
Nat. Biotechnol. 36 (6) 521-529 [2018-07-00; online 2018-05-21]
Affiliated researcher
PubMed DOI Crossref
Docking Screens for Dual Inhibitors of Disparate Drug Targets for Parkinson's Disease.
Jaiteh M, Zeifman A, Saarinen M, ..., Loza MI, Carlsson J
J Med Chem 61 (12) 5269-5278 [2018-06-28; online 2018-06-15]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Phenotypic Image Analysis Software Tools for Exploring and Understanding Big Image Data from Cell-Based Assays.
Smith K, Piccinini F, Balassa T, ..., Azizpour H, Horvath P
Cell Systems 6 (6) 636-653 [2018-06-27; online 2018-06-29]
Affiliated researcher
PubMed DOI Crossref
Model Communities Hint at Promiscuous Metabolic Linkages between Ubiquitous Free-Living Freshwater Bacteria.
Garcia SL, Buck M, Hamilton JJ, ..., McMahon KD, Eiler A
mSphere 3 (3) - [2018-06-27; online 2018-05-30]
Affiliated researcher Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
A reference cytochrome c oxidase subunit I database curated for hierarchical classification of arthropod metabarcoding data
Richardson RT, Bengtsson-Palme J, Gardiner MM, Johnson RM
PeerJ 6 (-) e5126 [2018-06-26; online 2018-06-26]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Understanding the Representative Gut Microbiota Dysbiosis in Metformin-Treated Type 2 Diabetes Patients Using Genome-Scale Metabolic Modeling.
Rosario D, Benfeitas R, Bidkhori G, ..., Shoaie S, Mardinoglu A
Front. Physiol. 9 (-) 775 [2018-06-25; online 2018-06-25]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy.
Vorobyeva A, Westerlund K, Mitran B, ..., Tolmachev V, Karlström AE
Sci Rep 8 (1) 9643 [2018-06-25; online 2018-06-25]
Affiliated researcher
PubMed DOI Crossref
Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4.
Søndergaard JN, van Heeringen SJ, Looman MWG, ..., Ansems M, Adema GJ
Front Immunol 9 (-) 1420 [2018-06-22; online 2018-06-22]
Affiliated researcher
PubMed DOI Crossref
In Vitro Evolution of Antibodies Inspired by In Vivo Evolution.
Persson H, Kirik U, Thörnqvist L, ..., Levander F, Ohlin M
Front Immunol 9 (-) 1391 [2018-06-21; online 2018-06-21]
Affiliated researcher
PubMed DOI Crossref
Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity.
Berglund E, Maaskola J, Schultz N, ..., Helleday T, Lundeberg J
Nat Commun 9 (1) 2419 [2018-06-20; online 2018-06-20]
Affiliated researcher
PubMed DOI Crossref
Protein Evolution and Design.
von Heijne G
Annu. Rev. Biochem. 87 (-) 101-103 [2018-06-20; online 2018-06-22]
Affiliated researcher
PubMed DOI Crossref
Gene expression profiling of periodontitis-affected gingival tissue by spatial transcriptomics.
Lundmark A, Gerasimcik N, Båge T, ..., Lundeberg J, Yucel-Lindberg T
Sci Rep 8 (1) 9370 [2018-06-19; online 2018-06-19]
Affiliated researcher
PubMed DOI Crossref
Poly(alkylidenimine) Dendrimers Functionalized with the Organometallic Moiety [Ru(η⁵-C₅H₅)(PPh₃)₂]⁺ as Promising Drugs Against Cisplatin-Resistant Cancer Cells and Human Mesenchymal Stem Cells.
Gouveia M, Figueira J, Jardim MG, ..., Rissanen K, Rodrigues J
Molecules 23 (6) - [2018-06-17; online 2018-06-17]
Affiliated researcher
PubMed DOI Crossref
eIF4E-Binding Proteins 1 and 2 Limit Macrophage Anti-Inflammatory Responses through Translational Repression of IL-10 and Cyclooxygenase-2.
William M, Leroux LP, Chaparro V, ..., Larsson O, Jaramillo M
J. Immunol. 200 (12) 4102-4116 [2018-06-15; online 2018-04-30]
Affiliated researcher
PubMed DOI Crossref
Stabilized Cyclic Peptides as Scavengers of Autoantibodies: Neutralization of Anticitrullinated Protein/Peptide Antibodies in Rheumatoid Arthritis.
Gunasekera S, Fernandes-Cerqueira C, Wennmalm S, ..., Jakobsson PJ, Göransson U
ACS Chem. Biol. 13 (6) 1525-1535 [2018-06-15; online 2018-05-24]
Affiliated researcher
PubMed DOI Crossref
Extracellular nanovesicles released from the commensal yeast Malassezia sympodialis are enriched in allergens and interact with cells in human skin.
Johansson HJ, Vallhov H, Holm T, ..., Lehtiö J, Scheynius A
Sci Rep 8 (1) 9182 [2018-06-15; online 2018-06-15]
Affiliated researcher
PubMed DOI Crossref
User-Friendly Genetic Conditional Knockout Strategies by CRISPR/Cas9.
Chen L, Ye Y, Dai H, ..., Ren W, Zhang W
Stem Cells Int 2018 (-) 9576959 [2018-06-14; online 2018-06-14]
Affiliated researcher
PubMed DOI Crossref
Complementary studies of lipid membrane dynamics using iSCAT and super-resolved fluorescence correlation spectroscopy.
Reina F, Galiani S, Shrestha D, ..., Kukura P, Eggeling C
J. Phys. D: Appl. Phys. 51 (23) 235401 [2018-06-13; online 2018-05-16]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Antischistosomal Properties of Hederacolchiside A1 Isolated from Pulsatilla chinensis.
Kang N, Shen W, Gao H, ..., Xu Q, Yu D
Molecules 23 (6) - [2018-06-13; online 2018-06-13]
Affiliated researcher
PubMed DOI Crossref
Investigating Holocene human population history in North Asia using ancient mitogenomes.
Kılınç GM, Kashuba N, Yaka R, ..., Storå J, Götherström A
Sci Rep 8 (1) 8969 [2018-06-12; online 2018-06-12]
Affiliated researcher
PubMed DOI Crossref
Associations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease: Longitudinal Analyses in the UK Biobank Study.
Tikkanen E, Gustafsson S, Ingelsson E
Circulation 137 (24) 2583-2591 [2018-06-12; online 2018-04-09]
Affiliated researcher
PubMed DOI Crossref
A universal platform for selection and high-resolution phenotypic screening of bacterial mutants using the nanowell slide.
Antypas H, Veses-Garcia M, Weibull E, Andersson-Svahn H, Richter-Dahlfors A
Lab Chip 18 (12) 1767-1777 [2018-06-12; online 2018-05-22]
Affiliated researcher
PubMed DOI Crossref
Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.
Gogola E, Duarte AA, de Ruiter JR, ..., Jonkers J, Rottenberg S
Cancer Cell 33 (6) 1078-1093.e12 [2018-06-11; online 2018-06-13]
Affiliated researcher
PubMed DOI Crossref
Whole Exome Sequencing of Patients from Multicase Families with Systemic Lupus Erythematosus Identifies Multiple Rare Variants.
Delgado-Vega AM, Martínez-Bueno M, Oparina NY, ..., Kozyrev SV, Alarcón-Riquelme ME
Sci Rep 8 (1) 8775 [2018-06-08; online 2018-06-08]
Affiliated researcher
PubMed DOI Crossref
An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.
Keedy DA, Hill ZB, Biel JT, ..., Wells JA, Fraser JS
Elife 7 (-) - [2018-06-07; online 2018-06-07]
DDLS Fellow Nicholas Pearce
PubMed DOI Crossref
Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance.
Nowak C, Hetty S, Salihovic S, ..., Fall T, Ingelsson E
Sci Rep 8 (1) 8691 [2018-06-06; online 2018-06-06]
Affiliated researcher
PubMed DOI Crossref
Mitochondrial Translation Efficiency Controls Cytoplasmic Protein Homeostasis.
Suhm T, Kaimal JM, Dawitz H, ..., Andréasson C, Ott M
Cell Metab. 27 (6) 1309-1322.e6 [2018-06-05; online 2018-05-10]
Affiliated researcher
PubMed DOI Crossref
Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids.
Treyer A, Mateus A, Wiśniewski JR, ..., Matsson P, Artursson P
Mol. Pharm. 15 (6) 2224-2233 [2018-06-04; online 2018-05-11]
Affiliated researcher