Vicent Pelechano

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SciLifeLab Fellow since 2016.

Primary: Shown in the list of current labels.

Year 2023

PubMed DOI Crossref
Atlas of mRNA translation and decay for bacteria.
Huch S, Nersisyan L, Ropat M, ..., Engstrand L, Pelechano V
Nat. Microbiol - (-) - [2023-05-22; online 2023-05-22]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling.
Altea-Manzano P, Doglioni G, Liu Y, ..., Malanchi I, Fendt SM
Nat Cancer 4 (3) 344-364 [2023-03-00; online 2023-02-02]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events.
Allen G, Weiss B, Panasenko OO, ..., Pelechano V, Collart MA
Genome Biol. 24 (1) 30 [2023-02-20; online 2023-02-20]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation.
Li B, Zeis P, Zhang Y, ..., Steinmetz LM, Pelechano V
Nat Commun 14 (1) 910 [2023-02-17; online 2023-02-17]
SciLifeLab Fellow Vicent Pelechano

Year 2022

PubMed DOI Crossref
OPUSeq simplifies detection of low-frequency DNA variants and uncovers fragmentase-associated artifacts.
Alekseenko A, Wang J, Barrett D, Pelechano V
NAR Genomics and Bioinformatics 4 (2) lqac048 [2022-06-00; online 2022-06-27]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Crowe-McAuliffe C, Murina V, Turnbull KJ, ..., Wilson DN, Hauryliuk V
Nat Commun 13 (1) 1860 [2022-04-06; online 2022-04-06]
SciLifeLab Fellow Vicent Pelechano

Year 2021

PubMed DOI Crossref
Not4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5A.
Allen GE, Panasenko OO, Villanyi Z, ..., Ignatova Z, Collart MA
Cell Reports 36 (9) 109633 [2021-08-31; online 2021-09-02]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Sample-to-answer COVID-19 nucleic acid testing using a low-cost centrifugal microfluidic platform with bead-based signal enhancement and smartphone read-out.
Soares RRG, Akhtar AS, Pinto IF, ..., Pelechano V, Russom A
Lab Chip 21 (15) 2932-2944 [2021-08-07; online 2021-06-11]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Rpb4 and Puf3 imprint and post-transcriptionally control the stability of a common set of mRNAs in yeast.
Garrido-Godino AI, Gupta I, Gutiérrez-Santiago F, ..., Pelechano V, Navarro F
RNA Biol 18 (8) 1206-1220 [2021-08-00; online 2020-11-01]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Simultaneous detection of SARS-CoV-2 and pandemic (H1N1) 2009 virus with real-time isothermal platform.
Yu L, Wang J, Li X, ..., Guo X, Yin X
Heliyon 7 (7) e07584 [2021-07-00; online 2021-07-15]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Recommendations for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samples.
Kubik S, Marques AC, Xing X, ..., Willig A, Xu Z
Clin. Microbiol. Infect. 27 (7) 1036.e1-1036.e8 [2021-07-00; online 2021-04-02]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Application of high-throughput 5'P sequencing for the study of co-translational mRNA decay.
Zhang Y, Pelechano V
STAR Protoc 2 (2) 100447 [2021-06-18; online 2021-03-31]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Using TIF-Seq2 to investigate association between 5´ and 3´mRNA ends.
Li B, Marques S, Wang J, Pelechano V
Meth. Enzymol. 655 (-) 85-118 [2021-05-28; online 2021-05-28]
SciLifeLab Fellow Vicent Pelechano
DOI Crossref
High-throughput 5′P sequencing enables the study of degradation-associated ribosome stalls
Zhang Y, Pelechano V
Cell Reports Methods 1 (1) 100001 [2021-04-02]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Direct detection of SARS-CoV-2 using non-commercial RT-LAMP reagents on heat-inactivated samples.
Alekseenko A, Barrett D, Pareja-Sanchez Y, ..., Yin X, Pelechano V
Sci Rep 11 (1) 1820 [2021-01-19; online 2021-01-19]
SciLifeLab Fellow Simon Elsässer Vicent Pelechano
PubMed DOI Crossref
A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae.
Rodríguez-Galán O, García-Gómez JJ, Rosado IV, ..., Kressler D, de la Cruz J
Nucleic Acids Res. 49 (1) 206-220 [2021-01-11; online 2020-12-18]
SciLifeLab Fellow Vicent Pelechano

Year 2020

PubMed DOI Crossref
Improved computational analysis of ribosome dynamics from 5′P degradome data using fivepseq
Nersisyan L, Ropat M, Pelechano V
NAR Genomics and Bioinformatics 2 (4) - [2020-11-24; online 2020-11-24]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
TIF-Seq2 disentangles overlapping isoforms in complex human transcriptomes.
Wang J, Li B, Marques S, ..., Wei W, Pelechano V
Nucleic Acids Res. 48 (18) e104 [2020-10-09; online 2020-08-21]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
The RNA exosome shapes the expression of key protein-coding genes.
Wu M, Karadoulama E, Lloret-Llinares M, ..., Jensen TH, Sandelin A
Nucleic Acids Res. 48 (15) 8509-8528 [2020-09-04; online 2020-07-28]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Transcriptional mutagenesis dramatically alters genome-wide p53 transactivation landscape.
Liang S, Ezerskyte M, Wang J, Pelechano V, Dreij K
Sci Rep 10 (1) 13513 [2020-08-11; online 2020-08-11]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Rapid Detection of COVID-19 Coronavirus Using a Reverse Transcriptional Loop-Mediated Isothermal Amplification (RT-LAMP) Diagnostic Platform.
Yu L, Wu S, Hao X, ..., Chen WH, Yin X
Clin. Chem. 66 (7) 975-977 [2020-07-01; online 2020-04-22]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis.
Thomas QA, Ard R, Liu J, ..., Pelechano V, Marquardt S
Nat Commun 11 (1) 2589 [2020-05-22; online 2020-05-22]
SciLifeLab Fellow Vicent Pelechano

Year 2019

PubMed DOI Crossref
Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.
Wei W, Hennig BP, Wang J, ..., Steinmetz LM, Pelechano V
Genome Res 29 (12) 1974-1984 [2019-12-00; online 2019-11-18]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection.
Garcia-Moreno M, Noerenberg M, Ni S, ..., Mohammed S, Castello A
Mol. Cell 74 (1) 196-211.e11 [2019-04-04; online 2019-02-21]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Transcription-driven chromatin repression of Intragenic transcription start sites.
Nielsen M, Ard R, Leng X, ..., Pelechano V, Marquardt S
PLoS Genet 15 (2) e1007969 [2019-02-00; online 2019-02-01]
SciLifeLab Fellow Vicent Pelechano

Year 2018

PubMed DOI Crossref
Tumor suppressor PNRC1 blocks rRNA maturation by recruiting the decapping complex to the nucleolus.
Gaviraghi M, Vivori C, Pareja Sanchez Y, ..., Cittaro D, Tonon G
EMBO J. 37 (23) - [2018-12-03; online 2018-10-29]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock.
Garre E, Pelechano V, Sánchez Del Pino M, Alepuz P, Sunnerhagen P
PLoS Genet 14 (7) e1007563 [2018-07-00; online 2018-07-30]
Affiliated researcher SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S
Nat Commun 9 (1) 2071 [2018-05-22; online 2018-05-22]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S
Nat Commun 9 (1) 1107 [2018-03-16; online 2018-03-16]
Affiliated researcher SciLifeLab Fellow Vicent Pelechano

Year 2017

PubMed DOI Crossref
From transcriptional complexity to cellular phenotypes: Lessons from yeast.
Pelechano V
Yeast 34 (12) 475-482 [2017-12-00; online 2017-10-11]
Affiliated researcher SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Multiplexed ChIP-Seq Using Direct Nucleosome Barcoding: A Tool for High-Throughput Chromatin Analysis.
Chabbert CD, Adjalley SH, Steinmetz LM, Pelechano V
Methods in molecular biology (Clifton, N.J.) 1689 (-) 177-194 [2017-10-14; online 2017-10-14]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation.
Gómez-Herreros F, Margaritis T, Rodríguez-Galán O, ..., Holstege FCP, Chávez S
Nucleic Acids Res. 45 (16) 9302-9318 [2017-09-19; online 2017-06-24]
Affiliated researcher SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences.
Pelechano V, Alepuz P
Nucleic Acids Res. 45 (12) 7326-7338 [2017-07-07; online 2017-05-27]
Affiliated researcher SciLifeLab Fellow Vicent Pelechano
DOI Crossref
Long Non Coding RNA Biology
Springer [book] (-) - [2017-00-00; online 2017-00-00]
SciLifeLab Fellow Vicent Pelechano

Year 2016

PubMed DOI Crossref
A global genetic interaction network maps a wiring diagram of cellular function.
Costanzo M, VanderSluis B, Koch EN, ..., Andrews B, Boone C
Science (New York, N.Y.) 353 (6306) aaf1420-aaf1420 [2016-09-23; online 2016-10-07]
Affiliated researcher SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters.
Chen Y, Pai AA, Herudek J, ..., Jensen TH, Sandelin A
Nat. Genet. 48 (9) 984-994 [2016-09-00; online 2016-07-25]
Affiliated researcher SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation.
Chlamydas S, Holz H, Samata M, ..., Steinmetz LM, Akhtar A
Nat. Struct. Mol. Biol. 23 (6) 580-589 [2016-06-00; online 2016-05-16]
Affiliated researcher SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons.
García-Martínez J, Delgado-Ramos L, Ayala G, ..., Chávez S, Pérez-Ortín JE
Nucleic Acids Res. 44 (8) 3643-3658 [2016-05-05; online 2015-12-29]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Rpb1 foot mutations demonstrate a major role of Rpb4 in mRNA stability during stress situations in yeast.
Garrido-Godino AI, García-López MC, García-Martínez J, ..., Pérez-Ortín JE, Navarro F
Biochim. Biophys. Acta 1859 (5) 731-743 [2016-05-00; online 2016-03-18]
Affiliated researcher SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Landscape and Dynamics of Transcription Initiation in the Malaria Parasite Plasmodium falciparum.
Adjalley SH, Chabbert CD, Klaus B, Pelechano V, Steinmetz LM
Cell Reports 14 (10) 2463-2475 [2016-03-15; online 2016-03-03]
Affiliated researcher SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Genome-wide quantification of 5'-phosphorylated mRNA degradation intermediates for analysis of ribosome dynamics.
Pelechano V, Wei W, Steinmetz LM
Nat Protoc 11 (2) 359-376 [2016-02-00; online 2016-01-28]
SciLifeLab Fellow Vicent Pelechano

Year 2015

PubMed DOI Crossref
Biotin-Genomic Run-On (Bio-GRO): A High-Resolution Method for the Analysis of Nascent Transcription in Yeast.
Jordán-Pla A, Miguel A, Serna E, Pelechano V, Pérez-Ortín JE
Methods in molecular biology (Clifton, N.J.) 1361 (-) 125-139 [2015-10-21; online 2015-10-21]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Genome-Wide Identification of Alternative Polyadenylation Events Using 3'T-Fill.
Wilkening S, Pelechano V, Steinmetz LM
Methods in molecular biology (Clifton, N.J.) 1358 (-) 295-302 [2015-10-16; online 2015-10-16]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
The Nuclear PolyA-Binding Protein Nab2p Is Essential for mRNA Production
Schmid M, Olszewski P, Pelechano V, ..., Steinmetz LM, Jensen TH
Cell Reports 12 (1) 128-139 [2015-07-00; online 2015-07-00]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Single-cell polyadenylation site mapping reveals 3' isoform choice variability.
Velten L, Anders S, Pekowska A, ..., Pelechano V, Steinmetz LM
Mol Syst Biol 11 (6) 812 [2015-06-03; online 2015-06-03]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Widespread Co-translational RNA Decay Reveals Ribosome Dynamics
Pelechano V, Wei W, Steinmetz LM
Cell 161 (6) 1400-1412 [2015-06-00; online 2015-06-00]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle
Jordán-Pla A, Gupta I, de Miguel-Jiménez L, ..., Pelechano V, Pérez-Ortín JE
Nucleic Acids Res. 43 (2) 787-802 [2015-01-30; online 2014-12-29]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
A high-throughput ChIP-Seq for large-scale chromatin studies.
Chabbert CD, Adjalley SH, Klaus B, ..., Pelechano V, Steinmetz LM
Mol Syst Biol 11 (1) 777 [2015-01-12; online 2015-01-12]
SciLifeLab Fellow Vicent Pelechano

Year 2014

PubMed DOI Crossref
Genome-wide identification of transcript start and end sites by transcript isoform sequencing
Pelechano V, Wei W, Jakob P, Steinmetz LM
Nat Protoc 9 (7) 1740-1759 [2014-07-00; online 2014-06-26]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits
Piazza I, Rutkowska A, Ori A, ..., Beck M, Haering CH
Nat Struct Mol Biol 21 (6) 560-568 [2014-06-00; online 2014-05-18]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Alternative polyadenylation diversifies post-transcriptional regulation by selective RNA-protein interactions
Gupta I, Clauder-Munster S, Klaus B, ..., Pelechano V, Steinmetz LM
Mol Syst Biol 10 (2) 719-719 [2014-03-20; online 2014-02-25]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Dynamic remodeling of histone modifications in response to osmotic stress in Saccharomyces cerevisiae
Magraner-Pardo L, Pelechano V, Coloma M, Tordera V
BMC Genomics 15 (1) 247 [2014-00-00; online 2014-00-00]
SciLifeLab Fellow Vicent Pelechano

Year 2013

PubMed DOI Crossref
Gene regulation by antisense transcription
Pelechano V, Steinmetz LM
Nat Rev Genet 14 (12) 880-893 [2013-12-00; online 2013-11-12]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Polyadenylation site–induced decay of upstream transcripts enforces promoter directionality
Ntini E, Järvelin AI, Bornholdt J, ..., Sandelin A, Jensen TH
Nat Struct Mol Biol 20 (8) 923-928 [2013-08-00; online 2013-07-14]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Extensive transcriptional heterogeneity revealed by isoform profiling
Pelechano V, Wei W, Steinmetz LM
Nature 497 (7447) 127-131 [2013-04-24; online 2013-04-24]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
An efficient method for genome-wide polyadenylation site mapping and RNA quantification
Wilkening S, Pelechano V, Järvelin AI, ..., Benes V, Steinmetz LM
Nucleic Acids Res. 41 (5) e65-e65 [2013-03-01; online 2013-01-07]
SciLifeLab Fellow Vicent Pelechano

Year 2012

PubMed DOI Crossref
Genome-wide polyadenylation site mapping.
Pelechano V, Wilkening S, Järvelin AI, Tekkedil MM, Steinmetz LM
Meth. Enzymol. 513 (-) 271-296 [2012-08-30; online 2012-08-30]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Rrp6p Controls mRNA Poly(A) Tail Length and Its Decoration with Poly(A) Binding Proteins
Schmid M, Poulsen MB, Olszewski P, ..., Moore C, Jensen TH
Molecular Cell 47 (2) 267-280 [2012-07-00; online 2012-07-00]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast.
García-Martínez J, Ayala G, Pelechano V, ..., Herrero E, Pérez-Ortín JE
Transcription 3 (1) 39-44 [2012-03-30; online 2012-03-30]
SciLifeLab Fellow Vicent Pelechano

Year 2011

PubMed DOI Crossref
The Conserved Foot Domain of RNA Pol II Associates with Proteins Involved in Transcriptional Initiation and/or Early Elongation
García-López MC, Pelechano V, Mirón-García MC, ..., Pérez-Ortín JE, Navarro F
Genetics 189 (4) 1235-1248 [2011-12-00; online 2011-09-27]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
A genomic view of mRNA turnover in yeast
Pérez-Ortín JE, Jordán-Pla A, Pelechano V
Comptes Rendus Biologies 334 (8-9) 647-654 [2011-08-00; online 2011-08-00]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Functional consequences of bidirectional promoters
Wei W, Pelechano V, Järvelin AI, Steinmetz LM
Trends in Genetics 27 (7) 267-276 [2011-07-00; online 2011-07-00]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Genomic-wide methods to evaluate transcription rates in yeast.
García-Martínez J, Pelechano V, Pérez-Ortín JE
Methods in molecular biology (Clifton, N.J.) 734 (-) 25-44 [2011-04-07; online 2011-04-07]
SciLifeLab Fellow Vicent Pelechano

Year 2010

PubMed DOI Crossref
A Complete Set of Nascent Transcription Rates for Yeast Genes
Pelechano V, Chávez S, Pérez-Ortín JE
PLoS ONE 5 (11) e15442 [2010-11-16; online 2010-11-16]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors
Rodríguez-Gil A, García-Martínez J, Pelechano V, ..., Pérez-Ortín JE, Chávez S
Nucleic Acids Res. 38 (14) 4651-4664 [2010-08-00; online 2010-04-10]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
There is a steady-state transcriptome in exponentially growing yeast cells
Pelechano V, Pérez-Ortín JE
Yeast 27 (7) 413-422 [2010-03-17; online 2010-03-17]
SciLifeLab Fellow Vicent Pelechano

Year 2009

PubMed DOI Crossref
Regulon-specific control of transcription elongation across the yeast genome.
Pelechano V, Jimeno-González S, Rodríguez-Gil A, ..., Pérez-Ortín JE, Chávez S
PLoS Genet 5 (8) e1000614 [2009-08-00; online 2009-08-21]
SciLifeLab Fellow Vicent Pelechano

Year 2008

PubMed DOI Crossref
The transcriptional inhibitor thiolutin blocks mRNA degradation in yeast.
Pelechano V, Pérez-Ortín JE
Yeast 25 (2) 85-92 [2008-02-00; online 2007-10-05]
SciLifeLab Fellow Vicent Pelechano

Year 2006

PubMed DOI Crossref
A genomic study of the inter-ORF distances in Saccharomyces cerevisiae.
Pelechano V, García-Martínez J, Pérez-Ortín JE
Yeast 23 (9) 689-699 [2006-07-15; online 2006-07-18]
SciLifeLab Fellow Vicent Pelechano

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Publications 9.1.3