Vicent Pelechano

54 publications

Year 2020

Rpb4 and Puf3 imprint and post-transcriptionally control the stability of a common set of mRNAs in yeast.
Garrido-Godino AI, Gupta I, Gutiérrez-Santiago F, ..., Pelechano V, Navarro F
RNA Biol - (-) 1-15 [2020-11-01; online 2020-11-01]
Vicent Pelechano
TIF-Seq2 disentangles overlapping isoforms in complex human transcriptomes.
Wang J, Li B, Marques S, ..., Wei W, Pelechano V
pii: 5894951 pmc: PMC7544212
Nucleic Acids Res. 48 (18) e104 [2020-10-09; online 2020-08-21]
Vicent Pelechano
The RNA exosome shapes the expression of key protein-coding genes.
Wu M, Karadoulama E, Lloret-Llinares M, ..., Jensen TH, Sandelin A
pii: 5876282 pmc: PMC7470964
Nucleic Acids Res. 48 (15) 8509-8528 [2020-09-04; online 2020-07-28]
Vicent Pelechano
Transcriptional mutagenesis dramatically alters genome-wide p53 transactivation landscape.
Liang S, Ezerskyte M, Wang J, Pelechano V, Dreij K
pii: 10.1038/s41598-020-70412-4 pmc: PMC7419513
Sci Rep 10 (1) 13513 [2020-08-11; online 2020-08-11]
Vicent Pelechano
Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis.
Thomas QA, Ard R, Liu J, ..., Pelechano V, Marquardt S
pii: 10.1038/s41467-020-16390-7 pmc: PMC7244574
Nat Commun 11 (1) 2589 [2020-05-22; online 2020-05-22]
Vicent Pelechano

Year 2019

Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.
Wei W, Hennig BP, Wang J, ..., Steinmetz LM, Pelechano V
pii: gr.243378.118 pmc: PMC6886497
Genome Res 29 (12) 1974-1984 [2019-12-00; online 2019-11-18]
Vicent Pelechano
System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection.
Garcia-Moreno M, Noerenberg M, Ni S, ..., Mohammed S, Castello A
pii: S1097-2765(19)30037-1 pmc: PMC6458987
Mol. Cell 74 (1) 196-211.e11 [2019-04-04; online 2019-02-21]
Vicent Pelechano
Transcription-driven chromatin repression of Intragenic transcription start sites.
Nielsen M, Ard R, Leng X, ..., Pelechano V, Marquardt S
pii: PGENETICS-D-18-01434 pmc: PMC6373976
PLoS Genet 15 (2) e1007969 [2019-02-00; online 2019-02-01]
Vicent Pelechano

Year 2018

Tumor suppressor PNRC1 blocks rRNA maturation by recruiting the decapping complex to the nucleolus.
Gaviraghi M, Vivori C, Pareja Sanchez Y, ..., Cittaro D, Tonon G
pii: embj.201899179 pmc: PMC6276881
EMBO J. 37 (23) - [2018-12-03; online 2018-10-29]
Vicent Pelechano
The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock.
Garre E, Pelechano V, Sánchez Del Pino M, Alepuz P, Sunnerhagen P
pii: PGENETICS-D-18-00309 pmc: PMC6085073
PLoS Genet 14 (7) e1007563 [2018-07-00; online 2018-07-30]
Affiliated researcher Vicent Pelechano
Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S
pii: 10.1038/s41467-018-04198-5 pmc: PMC5964109
Nat Commun 9 (1) 2071 [2018-05-22; online 2018-05-22]
Vicent Pelechano

Year 2017

The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation
Gómez-Herreros F, Margaritis T, Rodríguez-Galán O, ..., Holstege FCP, Chávez S
Nucleic Acids Res 45 (16) 9302-9318 [2017-09-19; online 2017-06-15]
Affiliated researcher Vicent Pelechano
Long Non Coding RNA Biology
Steinmetz LM, Pelechano V
Springer [book] (-) - [2017-00-00; online 2017-00-00]
Vicent Pelechano

Year 2016

A global genetic interaction network maps a wiring diagram of cellular function
Costanzo M, VanderSluis B, Koch EN, ..., Andrews B, Boone C
Science 353 (6306) aaf1420-aaf1420 [2016-09-23; online 2016-09-22]
Affiliated researcher Vicent Pelechano

Year 2015

The Nuclear PolyA-Binding Protein Nab2p Is Essential for mRNA Production
Schmid M, Olszewski P, Pelechano V, ..., Steinmetz LM, Jensen TH
Cell Reports 12 (1) 128-139 [2015-07-00; online 2015-07-00]
Vicent Pelechano
Widespread Co-translational RNA Decay Reveals Ribosome Dynamics
Pelechano V, Wei W, Steinmetz LM
Cell 161 (6) 1400-1412 [2015-06-00; online 2015-06-00]
Vicent Pelechano
Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle
Jordán-Pla A, Gupta I, de Miguel-Jiménez L, ..., Pelechano V, Pérez-Ortín JE
Nucleic Acids Res. 43 (2) 787-802 [2015-01-30; online 2014-12-29]
Vicent Pelechano
A high-throughput ChIP-Seq for large-scale chromatin studies.
Chabbert CD, Adjalley SH, Klaus B, ..., Pelechano V, Steinmetz LM
Mol Syst Biol 11 (1) 777 [2015-01-12; online 2015-01-12]
Vicent Pelechano

Year 2014

Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits
Piazza I, Rutkowska A, Ori A, ..., Beck M, Haering CH
Nat Struct Mol Biol 21 (6) 560-568 [2014-06-00; online 2014-05-18]
Vicent Pelechano
Alternative polyadenylation diversifies post-transcriptional regulation by selective RNA-protein interactions
Gupta I, Clauder-Munster S, Klaus B, ..., Pelechano V, Steinmetz LM
Mol Syst Biol 10 (2) 719-719 [2014-03-20; online 2014-02-25]
Vicent Pelechano

Year 2013

Gene regulation by antisense transcription
Pelechano V, Steinmetz LM
Nat Rev Genet 14 (12) 880-893 [2013-12-00; online 2013-11-12]
Vicent Pelechano
Polyadenylation site–induced decay of upstream transcripts enforces promoter directionality
Ntini E, Järvelin AI, Bornholdt J, ..., Sandelin A, Jensen TH
Nat Struct Mol Biol 20 (8) 923-928 [2013-08-00; online 2013-07-14]
Vicent Pelechano
Extensive transcriptional heterogeneity revealed by isoform profiling
Pelechano V, Wei W, Steinmetz LM
Nature 497 (7447) 127-131 [2013-04-24; online 2013-04-24]
Vicent Pelechano
An efficient method for genome-wide polyadenylation site mapping and RNA quantification
Wilkening S, Pelechano V, Järvelin AI, ..., Benes V, Steinmetz LM
Nucleic Acids Res. 41 (5) e65-e65 [2013-03-01; online 2013-01-07]
Vicent Pelechano

Year 2012

Genome-wide polyadenylation site mapping.
Pelechano V, Wilkening S, Järvelin AI, Tekkedil MM, Steinmetz LM
pii: B978-0-12-391938-0.00012-4
Meth. Enzymol. 513 (-) 271-296 [2012-08-30; online 2012-08-30]
Vicent Pelechano
Rrp6p Controls mRNA Poly(A) Tail Length and Its Decoration with Poly(A) Binding Proteins
Schmid M, Poulsen MB, Olszewski P, ..., Moore C, Jensen TH
Molecular Cell 47 (2) 267-280 [2012-07-00; online 2012-07-00]
Vicent Pelechano
The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast.
García-Martínez J, Ayala G, Pelechano V, ..., Herrero E, Pérez-Ortín JE
pii: 19416 pmc: PMC3361511
Transcription 3 (1) 39-44 [2012-03-30; online 2012-03-30]
Vicent Pelechano

Year 2011

The Conserved Foot Domain of RNA Pol II Associates with Proteins Involved in Transcriptional Initiation and/or Early Elongation
García-López MC, Pelechano V, Mirón-García MC, ..., Pérez-Ortín JE, Navarro F
Genetics 189 (4) 1235-1248 [2011-12-00; online 2011-09-27]
Vicent Pelechano
A genomic view of mRNA turnover in yeast
Pérez-Ortín JE, Jordán-Pla A, Pelechano V
Comptes Rendus Biologies 334 (8-9) 647-654 [2011-08-00; online 2011-08-00]
Vicent Pelechano
Functional consequences of bidirectional promoters
Wei W, Pelechano V, Järvelin AI, Steinmetz LM
Trends in Genetics 27 (7) 267-276 [2011-07-00; online 2011-07-00]
Vicent Pelechano
Genomic-wide methods to evaluate transcription rates in yeast.
García-Martínez J, Pelechano V, Pérez-Ortín JE
Methods in molecular biology (Clifton, N.J.) 734 (-) 25-44 [2011-04-07; online 2011-04-07]
Vicent Pelechano

Year 2010

A Complete Set of Nascent Transcription Rates for Yeast Genes
Pelechano V, Chávez S, Pérez-Ortín JE
PLoS ONE 5 (11) e15442 [2010-11-16; online 2010-11-16]
Vicent Pelechano
The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors
Rodríguez-Gil A, García-Martínez J, Pelechano V, ..., Pérez-Ortín JE, Chávez S
Nucleic Acids Res. 38 (14) 4651-4664 [2010-08-00; online 2010-04-10]
Vicent Pelechano

Year 2009

Regulon-specific control of transcription elongation across the yeast genome.
Pelechano V, Jimeno-González S, Rodríguez-Gil A, ..., Pérez-Ortín JE, Chávez S
PLoS Genet 5 (8) e1000614 [2009-08-00; online 2009-08-21]
Vicent Pelechano

Year 2008

Year 2006

A genomic study of the inter-ORF distances in Saccharomyces cerevisiae.
Pelechano V, García-Martínez J, Pérez-Ortín JE
Yeast 23 (9) 689-699 [2006-07-15; online 2006-07-18]
Vicent Pelechano