Sci Rep

Distribution of photosensitive fagopyrin in buckwheat flowers and its potential biological relevance.

Hornyák M, Kula-Maximenko M, Miszalski Z, ..., Göransson U, Slazak B

Sci Rep 15 (1) 36279 [2025-10-16; online 2025-10-16]

Associations of the intestinal microbiota with plasma bile acids and inflammation markers in Crohn's disease and ulcerative colitis.

Prast-Nielsen S, Granström AL, Kiasat A, ..., Gustafsson UO, Engstrand L

Sci Rep 15 (1) 35039 [2025-10-08; online 2025-10-08]

Cholinergic modulation enables scalable action selection learning in a computational model of the striatum.

González-Redondo Á, Garrido JA, Hellgren Kotaleski J, Grillner S, Ros E

Sci Rep 15 (1) 34902 [2025-10-07; online 2025-10-07]

Reliable on-treatment prognostication and target identification with a customized assay for circulating tumor DNA in patients with newly diagnosed pancreatic cancer.

Petersson A, Svensson M, Hau SO, ..., Gisselsson D, Jirström K

Sci Rep 15 (1) 34481 [2025-10-03; online 2025-10-03]

Widely-distributed freshwater microorganisms with streamlined genomes co-occur in cohorts with high abundance.

Rodríguez-Gijón A, Pacheco-Valenciana A, Milke F, ..., Rodriguez-R LM, Garcia SL

Sci Rep 15 (1) 34482 [2025-10-03; online 2025-10-03]

Sarahi Garcia SciLifeLab Fellow

Structural uncertainty in mapping Euro-Atlantic atmospheric rivers obscures understanding of associated meteorological extremes.

Thandlam V, Rutgersson A, Sahlée E

Sci Rep 15 (1) 33325 [2025-09-29; online 2025-09-29]

Sexual dimorphism in zebrafish liver proteins and implications for hepatic regeneration and diseases.

Niksirat H, Mengal K, Kor G, Steinbach C, Levander F

Sci Rep 15 (1) 33565 [2025-09-29; online 2025-09-29]

4D flow MRI enhances prototype testing of a total artificial heart.

Bakker T, Najar A, Finocchiaro T, ..., Lantz J, Ebbers T

Sci Rep 15 (1) 32533 [2025-09-15; online 2025-09-15]

Lab-on-PCB with integrated DNA amplification and electroanalytical detection for point-of-care diagnostics.

Thorapalli Muralidharan S, Hanze M, Ainla A, ..., Hamedi MM, Toldrà A

Sci Rep 15 (1) 32418 [2025-09-12; online 2025-09-12]

Immune-coagulation dynamics in severe COVID-19 revealed by autoantibody profiling and multi-omics integration.

Ambikan AT, Cederholm A, Rezene S, ..., Landegren N, Gupta S

Sci Rep 15 (1) 32149 [2025-09-01; online 2025-09-01]

Combinatorial DNMTs and EZH2 inhibition reprograms the H3K27me3 and DNAme-mediated onco-epigenome to suppress multiple myeloma proliferation.

Atienza Párraga A, Nylund P, Diamanti K, ..., Jernberg Wiklund H, Kalushkova A

Sci Rep 15 (1) 31568 [2025-08-27; online 2025-08-27]

Discovery of tumour indicating morphological changes in benign prostate biopsies through AI.

Chelebian E, Avenel C, Järemo H, ..., Bergh A, Wählby C

Sci Rep 15 (1) 30770 [2025-08-21; online 2025-08-21]

Impact of gas background on XFEL single-particle imaging.

You T, Bielecki J, Maia FRNC

Sci Rep 15 (1) 29559 [2025-08-12; online 2025-08-12]

Profiling of the microRNA transcriptome in feline whole blood.

Ohlsson Å, Hanås S, Holst BS, ..., Ljungvall I, Häggström J

Sci Rep 15 (1) 27962 [2025-07-31; online 2025-07-31]

Correction: Low coverage of species constrains the use of DNA barcoding to assess mosquito biodiversity.

Moraes Zenker M, Portella TP, Pessoa FAC, Bengtsson-Palme J, Galetti PM

Sci Rep 15 (1) 20045 [2025-06-11; online 2025-06-11]

DDLS Fellow

Evaluation of automatic cell free DNA extraction metrics using different blood collection tubes.

Andersson D, Kristiansson H, Luna Santamaría M, ..., Torinsson Naluai Å, Ståhlberg A

Sci Rep 15 (1) 19364 [2025-06-03; online 2025-06-03]

Metagenomic biodiversity assessment within an offshore wind farm.

Serivichyaswat PT, Scholte T, Wilms T, Stranddorf L, van der Valk T

Sci Rep 15 (1) 16786 [2025-05-14; online 2025-05-14]

DDLS Fellow Tom van der Valk

Cytoskeletal alterations in neuronal cells implicate Toxoplasma gondii secretory machinery and host microRNA-containing extracellular vesicles.

Mazza T, Aslanzadeh M, Berentsen L, ..., Friedländer MR, Barragan A

Sci Rep 15 (1) 12606 [2025-04-12; online 2025-04-12]

Marc Friedländer SciLifeLab Fellow

Long-term gamma-aminobutyric acid (GABA) treatment fails to regain beta-cell function in longstanding type 1 diabetes in a randomized trial.

Hill H, Lundkvist P, Tsatsaris G, ..., Espes D, Carlsson PO

Sci Rep 15 (1) 11530 [2025-04-04; online 2025-04-04]

Daniel Espes SciLifeLab Fellow

Oxygen level alters energy metabolism in bovine preimplantation embryos.

Boskovic N, Ivask M, Yazgeldi Gunaydin G, ..., Daub CO, Kere J

Sci Rep 15 (1) 11327 [2025-04-02; online 2025-04-02]

Lab-in-a-Fiber detection and capture of cells.

Varela JC, Harish AV, Maniewski P, ..., Russom A, Laurell F

Sci Rep 15 (1) 9694 [2025-03-20; online 2025-03-20]

Uncovering pre-cytokinetic block in cancer cells under shear stress using a disturbed flow-generating device.

Beresova L, Vitecek J, Protivánková I, ..., Bartek J, Mistrik M

Sci Rep 15 (1) 6457 [2025-02-22; online 2025-02-22]

Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.

Mazzaferro E, Mujica E, Zhang H, ..., Allalou A, den Hoed M

Sci Rep 15 (1) 5408 [2025-02-13; online 2025-02-13]

Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival.

van der Heiden AD, Pensch R, Agger S, ..., Lindblad-Toh K, Arendt ML

Sci Rep 15 (1) 4724 [2025-02-08; online 2025-02-08]

Diffusion Smart-seq3 of breast cancer spheroids to explore spatial tumor biology and test evolutionary principles of tumor heterogeneity.

Cougnoux A, Mahmoud L, Johnsson PA, ..., Sandberg R, Hausser J

Sci Rep 15 (1) 3811 [2025-01-30; online 2025-01-30]

Jean Hausser SciLifeLab Fellow

Targeting mutant p53: Evaluation of novel anti-p53R175H monoclonal antibodies as diagnostic tools.

Spiegelberg D, Hwang LA, Pua KH, ..., Nestor M, Lane D

Sci Rep 15 (1) 1000 [2025-01-06; online 2025-01-06]

Spatial transcriptomics unveils estrogen-modulated immune responses and structural alterations in the ectocervical mucosa of depot medroxyprogesterone acetate users.

Kaldhusdal V, Boger MF, Tjernlund A, ..., Czarnewski P, Broliden K

Sci Rep 15 (1) 1014 [2025-01-06; online 2025-01-06]

Addressing inter individual variability in CSF levels of brain derived proteins across neurodegenerative diseases.

Mravinacová S, Bergström S, Olofsson J, ..., Nilsson P, Månberg A

Sci Rep 15 (1) 668 [2025-01-03; online 2025-01-03]

DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells.

Cheung P, Persson J, Zhang B, ..., Löfblom J, Eriksson O

Sci Rep 15 (1) 417 [2025-01-02; online 2025-01-02]

Multi-omics analysis detail a submicroscopic inv(15)(q14q15) generating fusion transcripts and MEIS2 and NUSAP1 haploinsufficiency.

Ek M, Kvarnung M, Pettersson M, ..., Eisfeldt J, Lindstrand A

Sci Rep 14 (1) 30343 [2024-12-05; online 2024-12-05]

Author Correction: Integration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes.

Diamanti K, Visvanathar R, Pereira MJ, ..., Wadelius C, Ahlström H

Sci Rep 14 (1) 29632 [2024-11-28; online 2024-11-28]

The association between novel urinary kidney damage biomarkers and coronary atherosclerosis in an apparently healthy population.

Lin YT, Wuopio J, Larsson A, ..., Fall T, Ärnlöv J

Sci Rep 14 (1) 29215 [2024-11-25; online 2024-11-25]

The early transcriptional and post-transcriptional responses to fluconazole in sensitive and resistant Candida albicans.

Stevens I, Silao FG, Huch S, ..., Ljungdahl PO, Pelechano V

Sci Rep 14 (1) 29012 [2024-11-22; online 2024-11-22]

SciLifeLab Fellow

Cooperative role of LSD1 and CHD7 in regulating differentiation of mouse embryonic stem cells.

Malla S, Martinez-Gamero C, Kumari K, ..., Roman AC, Aguilo F

Sci Rep 14 (1) 28495 [2024-11-18; online 2024-11-18]

CCDC28A deficiency causes head-tail coupling defects and immotility in murine spermatozoa.

Stojanovic N, Hernández RO, Ramírez NT, ..., Hernández AH, Shibuya H

Sci Rep 14 (1) 26808 [2024-11-05; online 2024-11-05]

Autoantibodies to protein S may explain rare cases of coagulopathy following COVID-19 vaccination.

Yalcinkaya A, Cavalli M, Aranda-Guillén M, ..., Hallberg P, Landegren N

Sci Rep 14 (1) 24512 [2024-10-18; online 2024-10-18]

New connections of medication use and polypharmacy with the gut microbiota composition and functional potential in a large population.

Larsson A, Ericson U, Jönsson D, ..., Maziarz M, Orho-Melander M

Sci Rep 14 (1) 23723 [2024-10-10; online 2024-10-10]

Cancer associated variant enrichment CAVE, a gene agnostic approach to identify low burden variants in chronic lymphocytic leukemia.

Yaacov A, Lazarian G, Pandzic T, ..., Rosenberg S, Soussi T

Sci Rep 14 (1) 21962 [2024-09-20; online 2024-09-20]

Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in dried blood and saliva samples using antibody proximity extension assays (AbPEA).

Wang M, Kamali-Moghaddam M, Löf L, ..., Landegren U, Zhao H

Sci Rep 14 (1) 21655 [2024-09-17; online 2024-09-17]

The involvement of cyclotides in the heavy metal tolerance of Viola spp.

Sychta K, Słomka A, Shariatgorji R, ..., Göransson U, Slazak B

Sci Rep 14 (1) 19306 [2024-08-20; online 2024-08-20]

Systematic review and feasibility study on pre-analytical factors and genomic analyses on archival formalin-fixed paraffin-embedded breast cancer tissue.

Salgkamis D, Sifakis EG, Agartz S, ..., Matikas A, Zerdes I

Sci Rep 14 (1) 18275 [2024-08-06; online 2024-08-06]

OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids.

Mickols E, Meyer A, Handin N, ..., Karlgren M, Artursson P

Sci Rep 14 (1) 17334 [2024-07-27; online 2024-07-27]

Mikael Sellin SciLifeLab Fellow

Large-scale proteomics reveals precise biomarkers for detection of ovarian cancer in symptomatic women.

Ivansson E, Hedlund Lindberg J, Stålberg K, ..., Gyllensten U, Enroth S

Sci Rep 14 (1) 17288 [2024-07-27; online 2024-07-27]

Study on the temporal and spatial distribution of Culex mosquitoes in Hanoi, Vietnam.

Krambrich J, Nguyen-Tien T, Pham-Thanh L, ..., Lindahl JF, Lundkvist Å

Sci Rep 14 (1) 16573 [2024-07-17; online 2024-07-17]

A single-cell transcriptomic study of heterogeneity in human embryonic tanycytes.

Bai Y, Chen Q, Li Y

Sci Rep 14 (1) 15384 [2024-07-04; online 2024-07-04]

Predicting type 2 diabetes via machine learning integration of multiple omics from human pancreatic islets.

Rönn T, Perfilyev A, Oskolkov N, Ling C

Sci Rep 14 (1) 14637 [2024-06-25; online 2024-06-25]

PIK3CA mutations in endocrine-resistant breast cancer.

Schagerholm C, Robertson S, Toosi H, Sifakis EG, Hartman J

Sci Rep 14 (1) 12542 [2024-05-31; online 2024-05-31]

In vivo phage display identifies novel peptides for cardiac targeting.

Ivanova A, Kohl F, González-King Garibotti H, ..., Wiseman J, Dekker N

Sci Rep 14 (1) 12177 [2024-05-28; online 2024-05-28]

Elevated levels of IL-12/IL-23p40 in Nova Scotia Duck Tolling Retrievers with autoimmune disease and lymphoma.

Nilsson M, Kozyrev SV, Saellström S, ..., Hansson-Hamlin H, Rönnberg H

Sci Rep 14 (1) 11624 [2024-05-21; online 2024-05-21]

Compositional and functional differences of the vaginal microbiota of women with and without cervical dysplasia.

Norenhag J, Edfeldt G, Stålberg K, ..., Schuppe-Koistinen I, Olovsson M

Sci Rep 14 (1) 11183 [2024-05-16; online 2024-05-16]

Clear effects on root system architecture of winter wheat cultivars (Triticum aestivum L.) from cultivation environment and practices.

Cope JE, Berckx F, Lundmark J, ..., Karlsson I, Weih M

Sci Rep 14 (1) 11099 [2024-05-15; online 2024-05-15]

Loss of Y in regulatory T lymphocytes in the tumor micro-environment of primary colorectal cancers and liver metastases.

Wójcik M, Juhas U, Mohammadi E, ..., Filipowicz N, Dumanski JP

Sci Rep 14 (1) 9458 [2024-04-24; online 2024-04-24]

Long-read sequencing and optical mapping generates near T2T assemblies that resolves a centromeric translocation.

Ten Berk de Boer E, Ameur A, Bunikis I, ..., Eisfeldt J, Lindstrand A

Sci Rep 14 (1) 9000 [2024-04-18; online 2024-04-18]

Low coverage of species constrains the use of DNA barcoding to assess mosquito biodiversity.

Moraes Zenker M, Portella TP, Pessoa FAC, Bengtsson-Palme J, Galetti PM

Sci Rep 14 (1) 7432 [2024-03-28; online 2024-03-28]

DDLS Fellow

Caveolin-1 gene expression provides additional prognostic information combined with PAM50 risk of recurrence (ROR) score in breast cancer.

Godina C, Belting M, Vallon-Christersson J, ..., Bosch A, Jernström H

Sci Rep 14 (1) 6675 [2024-03-20; online 2024-03-20]

Genome wide association study in Swedish Labrador retrievers identifies genetic loci associated with hip dysplasia and body weight.

Kieler IN, Persson SM, Hagman R, ..., Lindblad-Toh K, Arendt ML

Sci Rep 14 (1) 6090 [2024-03-13; online 2024-03-13]

Cardiac biopsies reveal differences in transcriptomics between left and right ventricle in patients with or without diagnostic signs of heart failure.

Frisk C, Das S, Eriksson MJ, ..., Linde C, Persson B

Sci Rep 14 (1) 5811 [2024-03-09; online 2024-03-09]

Identification of microbial pathogens in Neolithic Scandinavian humans.

Bergfeldt N, Kırdök E, Oskolkov N, ..., Storå J, Götherström A

Sci Rep 14 (1) 5630 [2024-03-07; online 2024-03-07]

Essential role of local antibody distribution in mediating bone-resorbing effects.

Nurkkala-Karlsson M, Lagerquist MK, Gupta P, ..., Mellström D, Engdahl C

Sci Rep 14 (1) 5684 [2024-03-07; online 2024-03-07]

Population genomic analyses reveal that salinity and geographic isolation drive diversification in a free-living protist.

Rengefors K, Annenkova N, Wallenius J, ..., Kremp A, Ahrén D

Sci Rep 14 (1) 4986 [2024-02-29; online 2024-02-29]

Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia.

Bwanika HC, Leo IR, Struyf N, ..., Jafari R, Pokrovskaja Tamm K

Sci Rep 14 (1) 4000 [2024-02-18; online 2024-02-18]

Author Correction: Direct RNA targeted in situ sequencing for transcriptomic profiling in tissue.

Lee H, Marco Salas S, Gyllborg D, Nilsson M

Sci Rep 14 (1) 3153 [2024-02-07; online 2024-02-07]

Infectivity of exhaled SARS-CoV-2 aerosols is sufficient to transmit covid-19 within minutes.

Alsved M, Nyström K, Thuresson S, ..., Medstrand P, Löndahl J

Sci Rep 13 (1) 21245 [2023-12-01; online 2023-12-01]

Selection, characterization and in vivo evaluation of novel CD44v6-targeting antibodies for targeted molecular radiotherapy.

Mortensen ACL, Berglund H, Segerström L, ..., Frejd FY, Nestor M

Sci Rep 13 (1) 20648 [2023-11-24; online 2023-11-24]

Single-cell transcriptomics delineates the immune cell landscape in equine lower airways and reveals upregulation of FKBP5 in horses with asthma.

Riihimäki M, Fegraeus K, Nordlund J, ..., Hellman L, Raine A

Sci Rep 13 (1) 16261 [2023-09-27; online 2023-09-27]

Genetic atlas of hygro-and thermosensory cells in the vinegar fly Drosophila melanogaster.

Corthals K, Andersson V, Churcher A, Reimegård J, Enjin A

Sci Rep 13 (1) 15202 [2023-09-14; online 2023-09-14]

Identification of essential genes associated with SARS-CoV-2 infection as potential drug target candidates with machine learning algorithms.

Taheri G, Habibi M

Sci Rep 13 (1) 15141 [2023-09-13; online 2023-09-13]

DDLS Fellow Golnaz Taheri

Association of the human gut microbiota with vascular stiffness.

Cuadrat RRC, Goris T, Birukov A, ..., Wittenbecher C, Schulze MB

Sci Rep 13 (1) 13348 [2023-08-16; online 2023-08-16]

Clemens Wittenbecher DDLS Fellow

A novel quantitative targeted analysis of X-chromosome inactivation (XCI) using nanopore sequencing.

Johansson J, Lidéus S, Höijer I, ..., Bondeson ML, Wilbe M

Sci Rep 13 (1) 12856 [2023-08-08; online 2023-08-08]

Technology platform for facile handling of 3D hydrogel cell culture scaffolds.

Pohlit H, Bohlin J, Katiyar N, Hilborn J, Tenje M

Sci Rep 13 (1) 12829 [2023-08-07; online 2023-08-07]

Screening autism-associated environmental factors in differentiating human neural progenitors with fractional factorial design-based transcriptomics.

Arora A, Becker M, Marques C, ..., Lanekoff I, Tammimies K

Sci Rep 13 (1) 10519 [2023-06-29; online 2023-06-29]

Reference-based cell type matching of in situ image-based spatial transcriptomics data on primary visual cortex of mouse brain.

Zhang Y, Miller JA, Park J, ..., Lein ES, Scheuermann RH

Sci Rep 13 (1) 9567 [2023-06-13; online 2023-06-13]

The impact of TLR2 and aging on the humoral immune response to Staphylococcus aureus bacteremia in mice.

Gupta P, Hu Z, Kopparapu PK, ..., Jin T, Engdahl C

Sci Rep 13 (1) 8850 [2023-05-31; online 2023-05-31]

Comparison of SARS-CoV-2 whole genome sequencing using tiled amplicon enrichment and bait hybridization.

Koskela von Sydow A, Lindqvist CM, Asghar N, ..., Mölling P, Stenmark B

Sci Rep 13 (1) 6461 [2023-04-20; online 2023-04-20]

PIK3CA is recurrently mutated in canine mammary tumors, similarly to in human mammary neoplasia.

Arendt ML, Sakthikumar S, Melin M, ..., Rönnberg H, Lindblad-Toh K

Sci Rep 13 (1) 632 [2023-01-12; online 2023-01-12]

Endogenous incretin levels and risk of first incident cancer: a prospective cohort study.

Jujić A, Godina C, Belting M, ..., Jernström H, Magnusson M

Sci Rep 13 (1) 382 [2023-01-07; online 2023-01-07]

Author Correction: Self-reported symptom severity, general health, and impairment in post-acute phases of COVID-19: retrospective cohort study of Swedish public employees.

Larsson SB, von Feilitzen GS, Andersson ME, ..., Nilsson S, Sigström R

Sci Rep 13 (1) 313 [2023-01-06; online 2023-01-06]

STK4 protein expression pattern follows different trends in endometrioid and serous endometrial adenocarcinoma upon tumor progression.

Govorov I, Attarha S, Kovalevska L, ..., Kashuba E, Mints M

Sci Rep 12 (1) 22154 [2022-12-22; online 2022-12-22]

A conserved MTMR lipid phosphatase increasingly suppresses autophagy in brain neurons during aging.

Kovács T, Szinyákovics J, Billes V, ..., Maglóczky Z, Vellai T

Sci Rep 12 (1) 21817 [2022-12-17; online 2022-12-17]

Differentiated mental health patterns in pregnancy during COVID-19 first two waves in Sweden: a mixed methods study using digital phenotyping.

Fransson E, Karalexi M, Kimmel M, ..., Skalkidou A, Papadopoulos FC

Sci Rep 12 (1) 21253 [2022-12-08; online 2022-12-08]

Aporphine and isoquinoline derivatives block glioblastoma cell stemness and enhance temozolomide cytotoxicity.

Rodrigues-Junior DM, Raminelli C, Hassanie H, ..., Moustakas A, Vettore AL

Sci Rep 12 (1) 21113 [2022-12-07; online 2022-12-07]

Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes.

Bartuzi D, Kędzierska E, Targowska-Duda KM, ..., Poso A, Kaczor AA

Sci Rep 12 (1) 21192 [2022-12-07; online 2022-12-07]

Personalized health risk assessment based on single-cell RNA sequencing analysis of a male with 45, X/48, XYYY karyotype.

Koczkowska M, Jąkalski M, Birkholz-Walerzak D, ..., Mieczkowski J, Piotrowski A

Sci Rep 12 (1) 20854 [2022-12-02; online 2022-12-02]

Self-reported symptom severity, general health, and impairment in post-acute phases of COVID-19: retrospective cohort study of Swedish public employees.

Larsson SB, von Feilitzen GS, Andersson ME, ..., Nilsson S, Sigström R

Sci Rep 12 (1) 19818 [2022-11-17; online 2022-11-17]

Knowledge of the perturbation design is essential for accurate gene regulatory network inference.

Seçilmiş D, Hillerton T, Tjärnberg A, ..., Nordling TEM, Sonnhammer ELL

Sci Rep 12 (1) 16531 [2022-10-03; online 2022-10-03]

Spatio-temporal predictions of COVID-19 test positivity in Uppsala County, Sweden: a comparative approach.

van Zoest V, Varotsis G, Menzel U, ..., Martinell M, Fall T

Sci Rep 12 (1) 15176 [2022-09-07; online 2022-09-07]

Selective transfer of maternal antibodies in preterm and fullterm children.

Dolatshahi S, Butler AL, Pou C, ..., Brodin P, Alter G

Sci Rep 12 (1) 14937 [2022-09-02; online 2022-09-02]

Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model.

Selvin T, Fasterius E, Jarvius M, ..., Larsson R, Andersson CR

Sci Rep 12 (1) 11960 [2022-07-13; online 2022-07-13]

Integrated single cell and spatial transcriptomics reveal autoreactive differentiated B cells in joints of early rheumatoid arthritis.

Hardt U, Carlberg K, Af Klint E, ..., Ståhl PL, Malmström V

Sci Rep 12 (1) 11876 [2022-07-13; online 2022-07-13]

Development of gut microbiota during the first 2 years of life.

Wernroth ML, Peura S, Hedman AM, ..., Dicksved J, Fall T

Sci Rep 12 (1) 9080 [2022-05-31; online 2022-05-31]

Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma.

Ek F, Blom K, Selvin T, ..., Jarvius M, Fryknäs M

Sci Rep 12 (1) 8943 [2022-05-27; online 2022-05-27]

The vaginal microbiome and the risk of preterm birth: a systematic review and network meta-analysis.

Gudnadottir U, Debelius JW, Du J, ..., Fransson E, Brusselaers N

Sci Rep 12 (1) 7926 [2022-05-13; online 2022-05-13]

Direct RNA targeted in situ sequencing for transcriptomic profiling in tissue.

Lee H, Marco Salas S, Gyllborg D, Nilsson M

Sci Rep 12 (1) 7976 [2022-05-13; online 2022-05-13]

Interpretable machine learning identifies paediatric Systemic Lupus Erythematosus subtypes based on gene expression data.

Yones SA, Annett A, Stoll P, ..., Meadows JRS, Komorowski J

Sci Rep 12 (1) 7433 [2022-05-06; online 2022-05-06]

Genetics of smoking and risk of clonal hematopoiesis.

Levin MG, Nakao T, Zekavat SM, ..., Damrauer SM, Natarajan P

Sci Rep 12 (1) 7248 [2022-05-04; online 2022-05-04]

Abhishek Niroula DDLS Fellow

Multi-staged gene expression profiling reveals potential genes and the critical pathways in kidney cancer.

Khouja HI, Ashankyty IM, Bajrai LH, ..., Firoz A, Mobashir M

Sci Rep 12 (1) 7240 [2022-05-04; online 2022-05-04]

Rationale and performances of a data-driven method for computing the duration of pharmacological prescriptions using secondary data sources.

Pazzagli L, Liang D, Andersen M, ..., Khan AR, Sessa M

Sci Rep 12 (1) 6245 [2022-04-15; online 2022-04-15]

Author Correction: Symptoms and syndromes associated with SARS-CoV-2 infection and severity in pregnant women from two community cohorts.

Molteni E, Astley CM, Ma W, ..., Chan AT, Modat M

Sci Rep 12 (1) 6083 [2022-04-12; online 2022-04-12]

Grey matter correlates of affective and somatic symptoms of premenstrual dysphoric disorder.

Dubol M, Wikström J, Lanzenberger R, ..., Sundström-Poromaa I, Comasco E

Sci Rep 12 (1) 5996 [2022-04-09; online 2022-04-09]

Erika Comasco SciLifeLab Fellow

Author Correction: The architecture of the Plasmodiophora brassicae nuclear and mitochondrial genomes.

Stjelja S, Fogelqvist J, Tellgren-Roth C, Dixelius C

Sci Rep 12 (1) 5766 [2022-04-06; online 2022-04-06]

scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation.

Raine A, Lundmark A, Annett A, ..., Bergin C, Nordlund J

Sci Rep 12 (1) 5772 [2022-04-06; online 2022-04-06]

Author Correction: A Lab-in-a-Fiber optofluidic device using droplet microfluidics and laser-induced fluorescence for virus detection.

Parker HE, Sengupta S, Harish AV, ..., Russom A, Laurell F

Sci Rep 12 (1) 5104 [2022-03-24; online 2022-03-24]

A Lab-in-a-Fiber optofluidic device using droplet microfluidics and laser-induced fluorescence for virus detection.

Parker HE, Sengupta S, Harish AV, ..., Russom A, Laurell F

Sci Rep 12 (1) 3539 [2022-03-03; online 2022-03-03]

Optimization of cerebrospinal fluid microbial DNA metagenomic sequencing diagnostics.

Olausson J, Brunet S, Vracar D, ..., Jakobsson HE, Tang KW

Sci Rep 12 (1) 3378 [2022-03-01; online 2022-03-01]

A genome-wide association study in a large community-based cohort identifies multiple loci associated with susceptibility to bacterial and viral infections.

Tängdén T, Gustafsson S, Rao AS, Ingelsson E

Sci Rep 12 (1) 2582 [2022-02-16; online 2022-02-16]

The involvement of cyclotides in mutual interactions of violets and the two-spotted spider mite.

Slazak B, Jędrzejska A, Badyra B, ..., Göransson U, Kiełkiewicz M

Sci Rep 12 (1) 1914 [2022-02-03; online 2022-02-03]

An in silico analysis identifies drugs potentially modulating the cytokine storm triggered by SARS-CoV-2 infection.

Sanchez-Burgos L, Gómez-López G, Al-Shahrour F, Fernandez-Capetillo O

Sci Rep 12 (1) 1626 [2022-01-31; online 2022-01-31]

A multi-omics study of circulating phospholipid markers of blood pressure.

Liu J, de Vries PS, Del Greco M F, ..., Dehghan A, Demirkan A

Sci Rep 12 (1) 574 [2022-01-12; online 2022-01-12]

Biased TCR gene usage in citrullinated Tenascin C specific T-cells in rheumatoid arthritis.

Sharma RK, Boddul SV, Yoosuf N, ..., Klareskog L, Malmström V

Sci Rep 11 (1) 24512 [2021-12-31; online 2021-12-31]

Potential of [11C]UCB-J as a PET tracer for islets of Langerhans.

Puuvuori E, Rokka J, Carlsson PO, ..., Eriksson J, Eriksson O

Sci Rep 11 (1) 24466 [2021-12-28; online 2021-12-28]

FLT3-ITD allelic ratio and HLF expression predict FLT3 inhibitor efficacy in adult AML.

Kivioja J, Malani D, Kumar A, ..., Kallioniemi O, Heckman CA

Sci Rep 11 (1) 23565 [2021-12-07; online 2021-12-07]

Thaduri S, Marupakula S, Terenius O, ..., Locke B, de Miranda JR

Sci Rep 11 (1) 23214 [2021-12-01; online 2021-12-01]

Drug repurposing improves disease targeting 11-fold and can be augmented by network module targeting, applied to COVID-19.

Rivero-García I, Castresana-Aguirre M, Guglielmo L, Guala D, Sonnhammer ELL

Sci Rep 11 (1) 20687 [2021-10-19; online 2021-10-19]

Brain microvasculature endothelial cell orientation on micropatterned hydrogels is affected by glucose level variations.

Porras Hernández AM, Barbe L, Pohlit H, Tenje M, Antfolk M

Sci Rep 11 (1) 19608 [2021-10-04; online 2021-10-04]

Understanding the role of potential pathways and its components including hypoxia and immune system in case of oral cancer.

Bajrai LH, Sohrab SS, Mobashir M, ..., Rizvi MA, Azhar EI

Sci Rep 11 (1) 19576 [2021-10-01; online 2021-10-01]

ZBED6 regulates Igf2 expression partially through its regulation of miR483 expression.

Naboulsi R, Larsson M, Andersson L, Younis S

Sci Rep 11 (1) 19484 [2021-09-30; online 2021-09-30]

Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69.

Persson J, Puuvuori E, Zhang B, ..., Eriksson O, Löfblom J

Sci Rep 11 (1) 19151 [2021-09-27; online 2021-09-27]

Metabolic drift in the aging nervous system is reflected in human cerebrospinal fluid.

Peters K, Herman S, Khoonsari PE, ..., Neumann S, Kultima K

Sci Rep 11 (1) 18822 [2021-09-22; online 2021-09-22]

Purkinje cells located in the adult zebrafish valvula cerebelli exhibit variable functional responses.

Chang W, Pedroni A, Köster RW, Giacomello S, Ampatzis K

Sci Rep 11 (1) 18408 [2021-09-15; online 2021-09-15]

Author Correction: Acoustic focusing of beads and cells in hydrogel droplets.

Fornell A, Pohlit H, Shi Q, Tenje M

Sci Rep 11 (1) 17501 [2021-08-26; online 2021-08-26]

Single cell organization and cell cycle characterization of DNA stained multicellular tumor spheroids.

Olofsson K, Carannante V, Takai M, Önfelt B, Wiklund M

Sci Rep 11 (1) 17076 [2021-08-23; online 2021-08-23]

The ABCC4 gene is associated with pyometra in golden retriever dogs.

Arendt M, Ambrosen A, Fall T, ..., Lindblad-Toh K, Hagman R

Sci Rep 11 (1) 16647 [2021-08-17; online 2021-08-17]

Mutational patterns and clonal evolution from diagnosis to relapse in pediatric acute lymphoblastic leukemia.

Sayyab S, Lundmark A, Larsson M, ..., Nordlund J, Syvänen AC

Sci Rep 11 (1) 15988 [2021-08-06; online 2021-08-06]

DNA methylation of Vesicular Glutamate Transporters in the mesocorticolimbic brain following early-life stress and adult ethanol exposure-an explorative study.

Vrettou M, Yan L, Nilsson KW, ..., Nylander I, Comasco E

Sci Rep 11 (1) 15322 [2021-07-28; online 2021-07-28]

Erika Comasco SciLifeLab Fellow

Publisher Correction: A SARS-CoV-2 (COVID-19) biological network to find targets for drug repurposing.

Habibi M, Taheri G, Aghdam R

Sci Rep 11 (1) 15550 [2021-07-26; online 2021-07-26]

DDLS Fellow Golnaz Taheri

Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99.

Mattisson J, Danielsson M, Hammond M, ..., Halvardson J, Forsberg LA

Sci Rep 11 (1) 15160 [2021-07-26; online 2021-07-26]

MiR-486-3p was downregulated at microRNA profiling of adrenals of multiple endocrine neoplasia type 1 mice, and inhibited human adrenocortical carcinoma cell lines.

Li SC, Monazzam A, Razmara M, ..., Stålberg P, Skogseid B

Sci Rep 11 (1) 14772 [2021-07-20; online 2021-07-20]

Identification of V6.51L as a selectivity hotspot in stereoselective A2B adenosine receptor antagonist recognition.

Wang X, Jespers W, Prieto-Díaz R, ..., Heitman LH, Gutiérrez-de-Terán H

Sci Rep 11 (1) 14171 [2021-07-08; online 2021-07-08]

An artificial neural network approach integrating plasma proteomics and genetic data identifies PLXNA4 as a new susceptibility locus for pulmonary embolism.

Razzaq M, Iglesias MJ, Ibrahim-Kosta M, ..., Morange PE, Trégouët DA

Sci Rep 11 (1) 14015 [2021-07-07; online 2021-07-07]

Cyclotide host-defense tailored for species and environments in violets from the Canary Islands.

Slazak B, Kaltenböck K, Steffen K, ..., Andrén PE, Göransson U

Sci Rep 11 (1) 12452 [2021-06-14; online 2021-06-14]

Distinct microbial community along the chronic oil pollution continuum of the Persian Gulf converge with oil spill accidents.

Rezaei Somee M, Dastgheib SMM, Shavandi M, ..., Amoozegar MA, Mehrshad M

Sci Rep 11 (1) 11316 [2021-05-31; online 2021-05-31]

Klevebro S, Björkander S, Ekström S, ..., Bergström A, Melén E

Sci Rep 11 (1) 11391 [2021-05-31; online 2021-05-31]

Small molecule inhibitors of the mitochondrial ClpXP protease possess cytostatic potential and re-sensitize chemo-resistant cancers.

Meßner M, Mandl MM, Hackl MW, ..., Sieber SA, Pachmayr J

Sci Rep 11 (1) 11185 [2021-05-27; online 2021-05-27]

X-chromosome variants are associated with aldosterone producing adenomas.

Dutta RK, Larsson M, Arnesen T, ..., Gimm O, Söderkvist P

Sci Rep 11 (1) 10562 [2021-05-18; online 2021-05-18]

A SARS-CoV-2 (COVID-19) biological network to find targets for drug repurposing.

Habibi M, Taheri G, Aghdam R

Sci Rep 11 (1) 9378 [2021-04-30; online 2021-04-30]

DDLS Fellow Golnaz Taheri

Long-read-sequenced reference genomes of the seven major lineages of enterotoxigenic Escherichia coli (ETEC) circulating in modern time.

von Mentzer A, Blackwell GA, Pickard D, ..., Dougan G, Sjöling Å

Sci Rep 11 (1) 9256 [2021-04-29; online 2021-04-29]

Astrid von Mentzer DDLS Fellow

High throughput viscoelastic particle focusing and separation in spiral microchannels.

Kumar T, Ramachandraiah H, Iyengar SN, ..., Mårtensson G, Russom A

Sci Rep 11 (1) 8467 [2021-04-19; online 2021-04-19]

Intake of food rich in saturated fat in relation to subclinical atherosclerosis and potential modulating effects from single genetic variants.

Laguzzi F, Maitusong B, Strawbridge RJ, ..., Leander K, IMPROVE Study group

Sci Rep 11 (1) 7866 [2021-04-12; online 2021-04-12]

Acoustic focusing of beads and cells in hydrogel droplets.

Fornell A, Pohlit H, Shi Q, Tenje M

Sci Rep 11 (1) 7479 [2021-04-05; online 2021-04-05]

Association between pet ownership and sleep in the Swedish CArdioPulmonary bioImage Study (SCAPIS).

van Egmond LT, Titova OE, Lindberg E, Fall T, Benedict C

Sci Rep 11 (1) 7468 [2021-04-02; online 2021-04-02]

Symptoms and syndromes associated with SARS-CoV-2 infection and severity in pregnant women from two community cohorts.

Molteni E, Astley CM, Ma W, ..., Chan AT, Modat M

Sci Rep 11 (1) 6928 [2021-03-25; online 2021-03-25]

Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma.

Oksvold MP, Berglund UW, Gad H, ..., Helleday T, Våtsveen TK

Sci Rep 11 (1) 6317 [2021-03-18; online 2021-03-18]

Antibodies to SARS-CoV-2 and risk of past or future sick leave.

Dillner J, Elfström KM, Blomqvist J, ..., Mühr LSA, Conneryd Lundgren K

Sci Rep 11 (1) 5160 [2021-03-04; online 2021-03-04]

Author Correction: Targeted sequencing reveals the somatic mutation landscape in a Swedish breast cancer cohort.

Mathioudaki A, Ljungström V, Melin M, ..., Sjöblom T, Lindblad-Toh K

Sci Rep 11 (1) 5310 [2021-03-01; online 2021-03-01]

Characterization of the nuclear and cytosolic transcriptomes in human brain tissue reveals new insights into the subcellular distribution of RNA transcripts.

Zaghlool A, Niazi A, Björklund ÅK, ..., Ameur A, Feuk L

Sci Rep 11 (1) 4076 [2021-02-18; online 2021-02-18]

Author Correction: Cathepsin g Degrades Both Glycosylated and Unglycosylated Regions of Lubricin, a Synovial Mucin.

Huang S, Thomsson KA, Jin C, ..., Karlsson NG, Eisler T

Sci Rep 11 (1) 4238 [2021-02-15; online 2021-02-15]

66Ga-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [66Ga]Ga-NOTA-PEG2-RM26.

Rinne SS, Abouzayed A, Gagnon K, Tolmachev V, Orlova A

Sci Rep 11 (1) 3631 [2021-02-11; online 2021-02-11]

Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects.

Baquero JM, Benítez-Buelga C, Rajagopal V, ..., Benítez J, Osorio A

Sci Rep 11 (1) 3490 [2021-02-10; online 2021-02-10]

Direct detection of SARS-CoV-2 using non-commercial RT-LAMP reagents on heat-inactivated samples.

Alekseenko A, Barrett D, Pareja-Sanchez Y, ..., Yin X, Pelechano V

Sci Rep 11 (1) 1820 [2021-01-19; online 2021-01-19]

SciLifeLab Fellow Simon Elsässer

The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals.

Strawbridge RJ, Johnston KJA, Bailey MES, ..., Sennblad B, Smith DJ

Sci Rep 11 (1) 632 [2021-01-12; online 2021-01-12]

Defining eligible patients for allele-selective chemotherapies targeting NAT2 in colorectal cancer.

Rendo V, Kundu S, Rameika N, ..., Stoimenov I, Sjöblom T

Sci Rep 10 (1) 22436 [2020-12-31; online 2020-12-31]

The serine protease HtrA plays a key role in heat-induced dispersal of pneumococcal biofilms.

Chao Y, Bergenfelz C, Sun R, ..., Achour A, Hakansson AP

Sci Rep 10 (1) 22455 [2020-12-31; online 2020-12-31]

Whole-genome sequencing of recurrent neuroblastoma reveals somatic mutations that affect key players in cancer progression and telomere maintenance.

Fransson S, Martinez-Monleon A, Johansson M, ..., Kogner P, Martinsson T

Sci Rep 10 (1) 22432 [2020-12-31; online 2020-12-31]

Cell-cell fusion of mesenchymal cells with distinct differentiations triggers genomic and transcriptomic remodelling toward tumour aggressiveness.

Delespaul L, Gélabert C, Lesluyes T, ..., Lartigue L, Chibon F

Sci Rep 10 (1) 21634 [2020-12-10; online 2020-12-10]

Empty mesoporous silica particles significantly delay disease progression and extend survival in a mouse model of ALS.

Leyton-Jaimes MF, Ivert P, Hoeber J, ..., Israelson A, Kozlova EN

Sci Rep 10 (1) 20675 [2020-11-26; online 2020-11-26]

High CD45 expression of CD8+ and CD4+ T cells correlates with the size of HIV-1 reservoir in blood.

Petkov S, Bekele Y, Lakshmikanth T, ..., Brodin P, Chiodi F

Sci Rep 10 (1) 20425 [2020-11-24; online 2020-11-24]

Inactivation of mediator complex protein 22 in podocytes results in intracellular vacuole formation, podocyte loss and premature death.

Rodriguez PQ, Unnersjö-Jess D, Zambrano SS, ..., Ebarasi L, Patrakka J

Sci Rep 10 (1) 20037 [2020-11-18; online 2020-11-18]

Artificial intelligence application for rapid fabrication of size-tunable PLGA microparticles in microfluidics.

Damiati SA, Rossi D, Joensson HN, Damiati S

Sci Rep 10 (1) 19517 [2020-11-11; online 2020-11-11]

Targeted sequencing reveals the somatic mutation landscape in a Swedish breast cancer cohort.

Mathioudaki A, Ljungström V, Melin M, ..., Sjöblom T, Lindblad-Toh K

Sci Rep 10 (1) 19304 [2020-11-09; online 2020-11-09]

Increasing thermal stability and improving biodistribution of VEGFR2-binding affibody molecules by a combination of in silico and directed evolution approaches.

Güler R, Svedmark SF, Abouzayed A, Orlova A, Löfblom J

Sci Rep 10 (1) 18148 [2020-10-23; online 2020-10-23]

Epigenetic alterations in skin homing CD4+CLA+ T cells of atopic dermatitis patients.

Acevedo N, Benfeitas R, Katayama S, ..., Söderhäll C, Scheynius A

Sci Rep 10 (1) 18020 [2020-10-22; online 2020-10-22]

Longitudinal plasma inflammatory proteome profiling during pregnancy in the Born into Life study.

Hedman AM, Lundholm C, Andolf E, ..., Fall T, Almqvist C

Sci Rep 10 (1) 17819 [2020-10-20; online 2020-10-20]

Acrylamide alters CREB and retinoic acid signalling pathways during differentiation of the human neuroblastoma SH-SY5Y cell line.

Attoff K, Johansson Y, Cediel-Ulloa A, ..., Gliga A, Forsby A

Sci Rep 10 (1) 16714 [2020-10-07; online 2020-10-07]

Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes.

Eriksson O, Haack T, Hijazi Y, ..., Wagner M, Tillner J

Sci Rep 10 (1) 16758 [2020-10-07; online 2020-10-07]

Non-targeted urine metabolomics and associations with prevalent and incident type 2 diabetes.

Salihovic S, Broeckling CD, Ganna A, ..., Ärnlöv J, Nowak C

Sci Rep 10 (1) 16474 [2020-10-05; online 2020-10-05]

High-fat diet and estrogen impacts the colon and its transcriptome in a sex-dependent manner.

Hases L, Archer A, Indukuri R, ..., Korach-André M, Williams C

Sci Rep 10 (1) 16160 [2020-09-30; online 2020-09-30]

Northstar enables automatic classification of known and novel cell types from tumor samples.

Zanini F, Berghuis BA, Jones RC, ..., Clarke MF, Quake SR

Sci Rep 10 (1) 15251 [2020-09-17; online 2020-09-17]

Compositional and functional differences of the mucosal microbiota along the intestine of healthy individuals.

Vaga S, Lee S, Ji B, ..., Engstrand L, Shoaie S

Sci Rep 10 (1) 14977 [2020-09-11; online 2020-09-11]

Saeed Shoaie SciLifeLab Fellow

Twentieth-century emergence of antimicrobial resistant human- and bovine-associated Salmonella enterica serotype Typhimurium lineages in New York State.

Carroll LM, Huisman JS, Wiedmann M

Sci Rep 10 (1) 14428 [2020-09-02; online 2020-09-02]

DDLS Fellow Laura Carroll

Perturbation-based gene regulatory network inference to unravel oncogenic mechanisms.

Morgan D, Studham M, Tjärnberg A, ..., Nordling TEM, Sonnhammer ELL

Sci Rep 10 (1) 14149 [2020-08-25; online 2020-08-25]

Pathway-specific model estimation for improved pathway annotation by network crosstalk.

Castresana-Aguirre M, Sonnhammer ELL

Sci Rep 10 (1) 13585 [2020-08-12; online 2020-08-12]

Transcriptional mutagenesis dramatically alters genome-wide p53 transactivation landscape.

Liang S, Ezerskyte M, Wang J, Pelechano V, Dreij K

Sci Rep 10 (1) 13513 [2020-08-11; online 2020-08-11]

SciLifeLab Fellow

Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9-based approach.

von der Heyde B, Emmanouilidou A, Mazzaferro E, ..., Brooke HL, den Hoed M

Sci Rep 10 (1) 11831 [2020-07-16; online 2020-07-16]

Proof-of-concept for CRISPR/Cas9 gene editing in human preadipocytes: Deletion of FKBP5 and PPARG and effects on adipocyte differentiation and metabolism.

Kamble PG, Hetty S, Vranic M, ..., Pereira MJ, Eriksson JW

Sci Rep 10 (1) 10565 [2020-06-29; online 2020-06-29]

RNA-seq reveals altered gene expression levels in proximal tubular cell cultures compared to renal cortex but not during early glucotoxicity.

Nilsson LM, Castresana-Aguirre M, Scott L, Brismar H

Sci Rep 10 (1) 10390 [2020-06-25; online 2020-06-25]

Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish.

Banote RK, Chebli J, Şatır TM, ..., Abramsson A, Zetterberg H

Sci Rep 10 (1) 10127 [2020-06-23; online 2020-06-23]

Adipose tissue morphology, imaging and metabolomics predicting cardiometabolic risk and family history of type 2 diabetes in non-obese men.

Rawshani A, Eliasson B, Rawshani A, ..., Rosengren A, Smith U

Sci Rep 10 (1) 9973 [2020-06-19; online 2020-06-19]

Adil Mardinoglu SciLifeLab Fellow

Theoretical insights on helix repacking as the origin of P-glycoprotein promiscuity.

Bonito CA, Ferreira RJ, Ferreira MU, ..., Cordeiro MNDS, Dos Santos DJVA

Sci Rep 10 (1) 9823 [2020-06-17; online 2020-06-17]

High frequency of intermediary alleles in the HTT gene in Northern Sweden - The Swedish Huntingtin Alleles and Phenotype (SHAPE) study.

Sundblom J, Niemelä V, Ghazarian M, ..., Söderberg S, Stattin EL

Sci Rep 10 (1) 9853 [2020-06-17; online 2020-06-17]

Integration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes.

Diamanti K, Visvanathar R, Pereira MJ, ..., Wadelius C, Ahlström H

Sci Rep 10 (1) 8343 [2020-05-20; online 2020-05-20]

Proteomic profiles before and during weight loss: Results from randomized trial of dietary intervention.

Figarska SM, Rigdon J, Ganna A, ..., Gardner CD, Ingelsson E

Sci Rep 10 (1) 7913 [2020-05-13; online 2020-05-13]

The honeybee (Apis mellifera) developmental state shapes the genetic composition of the deformed wing virus-A quasispecies during serial transmission.

Yañez O, Chávez-Galarza J, Tellgren-Roth C, ..., Neumann P, de Miranda JR

Sci Rep 10 (1) 5956 [2020-04-06; online 2020-04-06]

Oxytocin Receptors Regulate Social Preference in Zebrafish.

Landin J, Hovey D, Xu B, ..., Kettunen P, Westberg L

Sci Rep 10 (1) 5435 [2020-03-25; online 2020-03-25]

Cathepsin g Degrades Both Glycosylated and Unglycosylated Regions of Lubricin, a Synovial Mucin.

Huang S, Thomsson KA, Jin C, ..., Karlsson NG, Eisler T

Sci Rep 10 (1) 4215 [2020-03-06; online 2020-03-06]

A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma.

Das Mahapatra K, Pasquali L, Søndergaard JN, ..., Kristensen LS, Pivarcsi A

Sci Rep 10 (1) 3637 [2020-02-27; online 2020-02-27]

Claudia Kutter SciLifeLab Fellow

Refined detection and phasing of structural aberrations in pediatric acute lymphoblastic leukemia by linked-read whole-genome sequencing.

Nordlund J, Marincevic-Zuniga Y, Cavelier L, ..., Lönnerholm G, Syvänen AC

Sci Rep 10 (1) 2512 [2020-02-13; online 2020-02-13]

Lipidomic profiles, lipid trajectories and clinical biomarkers in female elite endurance athletes.

Varga TV, Ali A, Herrera JAR, ..., Brunak S, Tornberg ÅB

Sci Rep 10 (1) 2349 [2020-02-11; online 2020-02-11]

Clinicopathological features and prognostic value of SOX11 in childhood acute lymphoblastic leukemia.

Grönroos T, Mäkinen A, Laukkanen S, ..., Heinäniemi M, Lohi O

Sci Rep 10 (1) 2043 [2020-02-06; online 2020-02-06]

Expression and regulation of FRMD6 in mouse DRG neurons and spinal cord after nerve injury.

Lyu C, Lyu GW, Mulder J, ..., Hökfelt T, Sten Shi TJ

Sci Rep 10 (1) 1880 [2020-02-05; online 2020-02-05]

Author Correction: ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes.

Bysani M, Agren R, Davegårdh C, ..., Bacos K, Ling C

Sci Rep 10 (1) 1744 [2020-01-29; online 2020-01-29]

Exploring the therapeutic potential of modern and ancestral phenylalanine/tyrosine ammonia-lyases as supplementary treatment of hereditary tyrosinemia.

Hendrikse NM, Holmberg Larsson A, Svensson Gelius S, ..., Nordling E, Syrén PO

Sci Rep 10 (1) 1315 [2020-01-28; online 2020-01-28]

Building de novo reference genome assemblies of complex eukaryotic microorganisms from single nuclei.

Montoliu-Nerin M, Sánchez-García M, Bergin C, ..., Johannesson H, Rosling A

Sci Rep 10 (1) 1303 [2020-01-28; online 2020-01-28]

Transcriptome analysis of fibroblasts from schizophrenia patients reveals differential expression of schizophrenia-related genes.

Etemadikhah M, Niazi A, Wetterberg L, Feuk L

Sci Rep 10 (1) 630 [2020-01-20; online 2020-01-20]

Evidence of altered mucosa-associated and fecal microbiota composition in patients with Irritable Bowel Syndrome.

Sundin J, Aziz I, Nordlander S, ..., Simrén M, Öhman L

Sci Rep 10 (1) 593 [2020-01-17; online 2020-01-17]

SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors.

Petroni M, Sahùn Roncero M, Ramponi V, ..., De Smaele E, Giannini G

Sci Rep 9 (1) 19623 [2019-12-23; online 2019-12-23]

Comparative genomics study reveals Red Sea Bacillus with characteristics associated with potential microbial cell factories (MCFs).

Othoum G, Prigent S, Derouiche A, ..., Mijakovic I, Essack M

Sci Rep 9 (1) 19254 [2019-12-17; online 2019-12-17]

Oral Microbiota Development in Early Childhood.

Kennedy B, Peura S, Hammar U, ..., Bertilsson S, Fall T

Sci Rep 9 (1) 19025 [2019-12-13; online 2019-12-13]

Sari Peura SciLifeLab Fellow

Exploring inflammatory signatures in arthritic joint biopsies with Spatial Transcriptomics.

Carlberg K, Korotkova M, Larsson L, ..., Ståhl PL, Malmström V

Sci Rep 9 (1) 18975 [2019-12-12; online 2019-12-12]

High throughput barcoding method for genome-scale phasing.

Redin D, Frick T, Aghelpasand H, ..., Olsen RA, Ahmadian A

Sci Rep 9 (1) 18116 [2019-12-02; online 2019-12-02]

Impact of Q-Griffithsin anti-HIV microbicide gel in non-human primates: In situ analyses of epithelial and immune cell markers in rectal mucosa.

Günaydın G, Edfeldt G, Garber DA, ..., Tjernlund A, Broliden K

Sci Rep 9 (1) 18120 [2019-12-02; online 2019-12-02]

Evaluation of Diffusion-Weighted MRI and FDG-PET/CT to Assess Response to AdCD40L treatment in Metastatic Melanoma Patients.

Schiza A, Irenaeus S, Ortiz-Nieto F, ..., Ullenhag GJ, Ahlström H

Sci Rep 9 (1) 18069 [2019-12-02; online 2019-12-02]

Author Correction: Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes.

Diamanti K, Cavalli M, Pan G, ..., Komorowski J, Wadelius C

Sci Rep 9 (1) 18158 [2019-11-28; online 2019-11-28]

Increase in negative charge of 68Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules.

Rinne SS, Dahlsson Leitao C, Gentry J, ..., Löfblom J, Orlova A

Sci Rep 9 (1) 17710 [2019-11-27; online 2019-11-27]

Effects of sampling strategy and DNA extraction on human skin microbiome investigations.

Bjerre RD, Hugerth LW, Boulund F, ..., Johansen JD, Engstrand L

Sci Rep 9 (1) 17287 [2019-11-21; online 2019-11-21]

Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26.

Mitran B, Thisgaard H, Rinne S, ..., Orlova A, Rosenström U

Sci Rep 9 (1) 17086 [2019-11-19; online 2019-11-19]

Improved power and precision with whole genome sequencing data in genome-wide association studies of inflammatory biomarkers.

Höglund J, Rafati N, Rask-Andersen M, ..., Ek WE, Johansson Å

Sci Rep 9 (1) 16844 [2019-11-14; online 2019-11-14]

Early symptoms and sensations as predictors of lung cancer: a machine learning multivariate model.

Levitsky A, Pernemalm M, Bernhardson BM, ..., Tishelman C, Eriksson LE

Sci Rep 9 (1) 16504 [2019-11-11; online 2019-11-11]

The architecture of the Plasmodiophora brassicae nuclear and mitochondrial genomes.

Stjelja S, Fogelqvist J, Tellgren-Roth C, Dixelius C

Sci Rep 9 (1) 15753 [2019-10-31; online 2019-10-31]

Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates.

Eriksson O, Velikyan I, Haack T, ..., Pierrou S, Wagner M

Sci Rep 9 (1) 14960 [2019-10-18; online 2019-10-18]

Author Correction: Extracellular nanovesicles released from the commensal yeast Malassezia sympodialis are enriched in allergens and interact with cells in human skin.

Johansson HJ, Vallhov H, Holm T, ..., Lehtiö J, Scheynius A

Sci Rep 9 (1) 15014 [2019-10-15; online 2019-10-15]

Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma.

Rad Pour S, Morikawa H, Kiani NA, ..., Hansson J, Tegnér J

Sci Rep 9 (1) 12150 [2019-08-21; online 2019-08-21]

Non-parametric combination analysis of multiple data types enables detection of novel regulatory mechanisms in T cells of multiple sclerosis patients.

Fernandes SJ, Morikawa H, Ewing E, ..., Tegnér J, Gomez-Cabrero D

Sci Rep 9 (1) 11996 [2019-08-19; online 2019-08-19]

TAF1, associated with intellectual disability in humans, is essential for embryogenesis and regulates neurodevelopmental processes in zebrafish.

Gudmundsson S, Wilbe M, Filipek-Górniok B, ..., Annerén G, Bondeson ML

Sci Rep 9 (1) 10730 [2019-07-24; online 2019-07-24]

A collagen-based microwell migration assay to study NK-target cell interactions.

Olofsson PE, Brandt L, Magnusson KEG, ..., Jaldén J, Önfelt B

Sci Rep 9 (1) 10672 [2019-07-23; online 2019-07-23]

Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes.

Diamanti K, Cavalli M, Pan G, ..., Komorowski J, Wadelius C

Sci Rep 9 (1) 9653 [2019-07-04; online 2019-07-04]

Single-cell RNA-seq variant analysis for exploration of genetic heterogeneity in cancer.

Fasterius E, Uhlén M, Al-Khalili Szigyarto C

Sci Rep 9 (1) 9524 [2019-07-02; online 2019-07-02]

Optimal composition and position of histidine-containing tags improves biodistribution of 99mTc-labeled DARPin G3.

Vorobyeva A, Schulga A, Konovalova E, ..., Tolmachev V, Deyev SM

Sci Rep 9 (1) 9405 [2019-06-28; online 2019-06-28]

A rapid smartphone-based lactate dehydrogenase test for neonatal diagnostics at the point of care.

Halvorsen CP, Olson L, Araújo AC, ..., Winbladh B, Russom A

Sci Rep 9 (1) 9301 [2019-06-26; online 2019-06-26]

Coro2b, a podocyte protein downregulated in human diabetic nephropathy, is involved in the development of protamine sulphate-induced foot process effacement.

Schwarz A, Möller-Hackbarth K, Ebarasi L, ..., Lal M, Patrakka J

Sci Rep 9 (1) 8888 [2019-06-20; online 2019-06-20]

Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles.

Fredolini C, Byström S, Sanchez-Rivera L, ..., Lehtiö J, Schwenk JM

Sci Rep 9 (1) 8324 [2019-06-06; online 2019-06-06]

ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes.

Bysani M, Agren R, Davegårdh C, ..., Bacos K, Ling C

Sci Rep 9 (1) 7785 [2019-05-23; online 2019-05-23]

Evidence of large genetic influences on dog ownership in the Swedish Twin Registry has implications for understanding domestication and health associations.

Fall T, Kuja-Halkola R, Dobney K, Westgarth C, Magnusson PKE

Sci Rep 9 (1) 7554 [2019-05-17; online 2019-05-17]

Genetic variation in CADM2 as a link between psychological traits and obesity.

Morris J, Bailey MES, Baldassarre D, ..., Smith DJ, Strawbridge RJ

Sci Rep 9 (1) 7339 [2019-05-14; online 2019-05-14]

Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake.

Rosestedt M, Andersson KG, Rinne SS, ..., Tolmachev V, Orlova A

Sci Rep 9 (1) 6779 [2019-05-01; online 2019-05-01]

The horse Y chromosome as an informative marker for tracing sire lines.

Felkel S, Vogl C, Rigler D, ..., Brem G, Wallner B

Sci Rep 9 (1) 6095 [2019-04-15; online 2019-04-15]

Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations.

Filppula AM, Parvizi R, Mateus A, Baranczewski P, Artursson P

Sci Rep 9 (1) 5850 [2019-04-10; online 2019-04-10]

Heterogeneous drug tissue binding in brain regions of rats, Alzheimer's patients and controls: impact on translational drug development.

Gustafsson S, Sehlin D, Lampa E, Hammarlund-Udenaes M, Loryan I

Sci Rep 9 (1) 5308 [2019-03-29; online 2019-03-29]

Transmission dynamics study of tuberculosis isolates with whole genome sequencing in southern Sweden.

Alaridah N, Hallbäck ET, Tångrot J, ..., Kaijser B, Godaly G

Sci Rep 9 (1) 4931 [2019-03-20; online 2019-03-20]

A microfluidic platform towards automated multiplexed in situ sequencing.

Maïno N, Hauling T, Cappi G, ..., Dupouy DG, Nilsson M

Sci Rep 9 (1) 3542 [2019-03-05; online 2019-03-05]

Transcriptomics of cardiac biopsies reveals differences in patients with or without diagnostic parameters for heart failure with preserved ejection fraction.

Das S, Frisk C, Eriksson MJ, ..., Linde C, Persson B

Sci Rep 9 (1) 3179 [2019-02-28; online 2019-02-28]

A novel mutation tolerant padlock probe design for multiplexed detection of hypervariable RNA viruses.

Ciftci S, Neumann F, Hernández-Neuta I, ..., Madaboosi N, Nilsson M

Sci Rep 9 (1) 2872 [2019-02-27; online 2019-02-27]

Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases.

Cavalli M, Baltzer N, Umer HM, ..., Komorowski J, Wadelius C

Sci Rep 9 (1) 2695 [2019-02-25; online 2019-02-25]

Prediction of response to anti-cancer drugs becomes robust via network integration of molecular data.

Franco M, Jeggari A, Peuget S, ..., Selivanova G, Alexeyenko A

Sci Rep 9 (1) 2379 [2019-02-20; online 2019-02-20]

Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111.

Rinne SS, Leitao CD, Mitran B, ..., Löfblom J, Orlova A

Sci Rep 9 (1) 655 [2019-01-24; online 2019-01-24]

Chromophore pre-maturation for improved speed and sensitivity of split-GFP monitoring of protein secretion.

Lundqvist M, Thalén N, Volk AL, ..., Uhlen M, Rockberg J

Sci Rep 9 (1) 310 [2019-01-22; online 2019-01-22]

Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier.

Mäe MA, Li T, Bertuzzi G, ..., Betsholtz C, Genové G

Sci Rep 8 (1) 17462 [2018-11-29; online 2018-11-29]

Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice.

Håversen L, Sundelin JP, Mardinoglu A, ..., Levin M, Borén J

Sci Rep 8 (1) 16973 [2018-11-19; online 2018-11-19]

Adil Mardinoglu SciLifeLab Fellow

Expression profiling and in situ screening of circular RNAs in human tissues.

Zaghlool A, Ameur A, Wu C, ..., Nilsson M, Feuk L

Sci Rep 8 (1) 16953 [2018-11-16; online 2018-11-16]

Dog characteristics and future risk of asthma in children growing up with dogs.

Fall T, Ekberg S, Lundholm C, Fang F, Almqvist C

Sci Rep 8 (1) 16899 [2018-11-15; online 2018-11-15]

Author Correction: Dilution of whisky - the molecular perspective.

Karlsson BCG, Friedman R

Sci Rep 8 (1) 16448 [2018-11-01; online 2018-11-01]

Single-Stranded Nucleic Acids Regulate TLR3/4/7 Activation through Interference with Clathrin-Mediated Endocytosis.

Järver P, Dondalska A, Poux C, ..., LeGrand R, Spetz AL

Sci Rep 8 (1) 15841 [2018-10-26; online 2018-10-26]

A systems-approach reveals human nestin is an endothelial-enriched, angiogenesis-independent intermediate filament protein.

Dusart P, Fagerberg L, Perisic L, ..., Odeberg J, Butler LM

Sci Rep 8 (1) 14668 [2018-10-02; online 2018-10-02]

A Non-Targeted LC-MS Profiling Reveals Elevated Levels of Carnitine Precursors and Trimethylated Compounds in the Cord Plasma of Pre-Eclamptic Infants.

Jääskeläinen T, Kärkkäinen O, Jokkala J, ..., Laivuori H, FINNPEC

Sci Rep 8 (1) 14616 [2018-10-02; online 2018-10-02]

Uptake dynamics in the Lactose permease (LacY) membrane protein transporter.

Kimanius D, Lindahl E, Andersson M

Sci Rep 8 (1) 14324 [2018-09-25; online 2018-09-25]

Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome.

Lovric A, Granér M, Bjornson E, ..., Mardinoglu A, Boren J

Sci Rep 8 (1) 14200 [2018-09-21; online 2018-09-21]

Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow

Promoter Usage and Dynamics in Vascular Smooth Muscle Cells Exposed to Fibroblast Growth Factor-2 or Interleukin-1β.

Alhendi AMN, Patrikakis M, Daub CO, ..., Arner E, Khachigian LM

Sci Rep 8 (1) 13164 [2018-09-03; online 2018-09-03]

Characterization of avian influenza virus attachment patterns to human and pig tissues.

Eriksson P, Lindskog C, Engholm E, ..., Jourdain E, Ellström P

Sci Rep 8 (1) 12215 [2018-08-15; online 2018-08-15]

Stationary and portable sequencing-based approaches for tracing wastewater contamination in urban stormwater systems.

Hu YOO, Ndegwa N, Alneberg J, ..., Fagerberg J, Andersson AF

Sci Rep 8 (1) 11907 [2018-08-09; online 2018-08-09]

Mitochondrial genomes reveal an east to west cline of steppe ancestry in Corded Ware populations.

Juras A, Chyleński M, Ehler E, ..., Jakobsson M, Kośko A

Sci Rep 8 (1) 11603 [2018-08-02; online 2018-08-02]

Analysis of public RNA-sequencing data reveals biological consequences of genetic heterogeneity in cell line populations.

Fasterius E, Al-Khalili Szigyarto C

Sci Rep 8 (1) 11226 [2018-07-25; online 2018-07-25]

Whole genome SNP-associated signatures of local adaptation in honeybees of the Iberian Peninsula.

Henriques D, Wallberg A, Chávez-Galarza J, ..., Webster MT, Pinto MA

Sci Rep 8 (1) 11145 [2018-07-24; online 2018-07-24]

Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome.

Sork H, Corso G, Krjutskov K, ..., Mäger I, El Andaloussi S

Sci Rep 8 (1) 10813 [2018-07-17; online 2018-07-17]

3D Maps of Mineral Composition and Hydroxyapatite Orientation in Fossil Bone Samples Obtained by X-ray Diffraction Computed Tomography.

Mürer FK, Sanchez S, Álvarez-Murga M, ..., Bech M, Breiby DW

Sci Rep 8 (1) 10052 [2018-07-03; online 2018-07-03]

Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy.

Vorobyeva A, Westerlund K, Mitran B, ..., Tolmachev V, Karlström AE

Sci Rep 8 (1) 9643 [2018-06-25; online 2018-06-25]

Gene expression profiling of periodontitis-affected gingival tissue by spatial transcriptomics.

Lundmark A, Gerasimcik N, Båge T, ..., Lundeberg J, Yucel-Lindberg T

Sci Rep 8 (1) 9370 [2018-06-19; online 2018-06-19]

Extracellular nanovesicles released from the commensal yeast Malassezia sympodialis are enriched in allergens and interact with cells in human skin.

Johansson HJ, Vallhov H, Holm T, ..., Lehtiö J, Scheynius A

Sci Rep 8 (1) 9182 [2018-06-15; online 2018-06-15]

Investigating Holocene human population history in North Asia using ancient mitogenomes.

Kılınç GM, Kashuba N, Yaka R, ..., Storå J, Götherström A

Sci Rep 8 (1) 8969 [2018-06-12; online 2018-06-12]

Whole Exome Sequencing of Patients from Multicase Families with Systemic Lupus Erythematosus Identifies Multiple Rare Variants.

Delgado-Vega AM, Martínez-Bueno M, Oparina NY, ..., Kozyrev SV, Alarcón-Riquelme ME

Sci Rep 8 (1) 8775 [2018-06-08; online 2018-06-08]

Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance.

Nowak C, Hetty S, Salihovic S, ..., Fall T, Ingelsson E

Sci Rep 8 (1) 8691 [2018-06-06; online 2018-06-06]

Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison's disease in Sweden.

Eriksson D, Bianchi M, Landegren N, ..., Rosengren Pielberg G, Kämpe O

Sci Rep 8 (1) 8395 [2018-05-30; online 2018-05-30]

Author Correction: Rapid signal enhancement method for nanoprobe-based biosensing.

Dias JT, Svedberg G, Nystrand M, Andersson-Svahn H, Gantelius J

Sci Rep 8 (1) 8184 [2018-05-22; online 2018-05-22]

Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants.

Zhou A, Taylor AE, Karhunen V, ..., Llewellyn DJ, Hyppönen E

Sci Rep 8 (1) 7526 [2018-05-14; online 2018-05-14]

RNA-sequencing reveals long-term effects of silver nanoparticles on human lung cells.

Gliga AR, Di Bucchianico S, Lindvall J, Fadeel B, Karlsson HL

Sci Rep 8 (1) 6668 [2018-04-27; online 2018-04-27]

Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.

Tikkanen E, Gustafsson S, Amar D, ..., Ashley EA, Ingelsson E

Sci Rep 8 (1) 6451 [2018-04-24; online 2018-04-24]

Inter-laboratory testing of the effect of DNA blocking reagent G2 on DNA extraction from low-biomass clay samples.

Jacobsen CS, Nielsen TK, Vester JK, ..., Ekelund F, Bælum J

Sci Rep 8 (1) 5711 [2018-04-09; online 2018-04-09]

Systemic and specific effects of antihypertensive and lipid-lowering medication on plasma protein biomarkers for cardiovascular diseases.

Enroth S, Maturi V, Berggrund M, ..., Johansson Å, Gyllensten U

Sci Rep 8 (1) 5531 [2018-04-03; online 2018-04-03]

Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes.

Klaesson A, Grannas K, Ebai T, ..., Söderberg O, Landegren U

Sci Rep 8 (1) 5400 [2018-03-29; online 2018-03-29]

Peptide ion channel toxins from the bootlace worm, the longest animal on Earth.

Jacobsson E, Andersson HS, Strand M, ..., Tytgat J, Göransson U

Sci Rep 8 (1) 4596 [2018-03-22; online 2018-03-22]

ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease.

Bremer HD, Landegren N, Sjöberg R, ..., Kämpe O, Hansson-Hamlin H

Sci Rep 8 (1) 4852 [2018-03-19; online 2018-03-19]

Cost-effective generation of precise label-free quantitative proteomes in high-throughput by microLC and data-independent acquisition.

Vowinckel J, Zelezniak A, Bruderer R, ..., Reiter L, Ralser M

Sci Rep 8 (1) 4346 [2018-03-12; online 2018-03-12]

Antibodies in children with malaria to PfEMP1, RIFIN and SURFIN expressed at the Plasmodium falciparum parasitized red blood cell surface.

Quintana MDP, Ch'ng JH, Moll K, ..., Qundos U, Wahlgren M

Sci Rep 8 (1) 3262 [2018-02-19; online 2018-02-19]

Permeability and ammonia selectivity in aquaporin TIP2;1: linking structure to function.

Lindahl V, Gourdon P, Andersson M, Hess B

Sci Rep 8 (1) 2995 [2018-02-14; online 2018-02-14]

Phenotypic co-receptor tropism and Maraviroc sensitivity in HIV-1 subtype C from East Africa.

Siddik AB, Haas A, Rahman MS, ..., Klimkait T, Neogi U

Sci Rep 8 (1) 2363 [2018-02-05; online 2018-02-05]

ITGB1-dependent upregulation of Caveolin-1 switches TGFβ signalling from tumour-suppressive to oncogenic in prostate cancer.

Pellinen T, Blom S, Sánchez S, ..., Kallioniemi O, Del Pozo MA

Sci Rep 8 (1) 2338 [2018-02-05; online 2018-02-05]

Targeted plasma proteomics identifies a novel, robust association between cornulin and Swedish moist snuff.

Sundkvist A, Myte R, Bodén S, ..., Harlid S, van Guelpen B

Sci Rep 8 (1) 2320 [2018-02-02; online 2018-02-02]

Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound.

Islam MK, Strand M, Saleeb M, ..., Elofsson M, Evander M

Sci Rep 8 (1) 1925 [2018-01-31; online 2018-01-31]

A Single Bout of Electroacupuncture Remodels Epigenetic and Transcriptional Changes in Adipose Tissue in Polycystic Ovary Syndrome.

Kokosar M, Benrick A, Perfilyev A, ..., Ling C, Stener-Victorin E

Sci Rep 8 (1) 1878 [2018-01-30; online 2018-01-30]

Increased Expression of GLP-1R in Proliferating Islets of Men1 Mice is Detectable by [68Ga]Ga-DO3A-VS-Cys40-Exendin-4 /PET.

Monazzam A, Lau J, Velikyan I, ..., Eriksson O, Skogseid B

Sci Rep 8 (1) 748 [2018-01-15; online 2018-01-15]

Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications.

Nassa G, Giurato G, Cimmino G, ..., Weisz A, Tarallo R

Sci Rep 8 (1) 498 [2018-01-11; online 2018-01-11]

Impacts of feeding preweaned calves milk containing drug residues on the functional profile of the fecal microbiota.

Pereira RVV, Carroll LM, Lima S, ..., Bicalho RC, Warnick LD

Sci Rep 8 (1) 554 [2018-01-11; online 2018-01-11]

DDLS Fellow Laura Carroll

Discovering viral genomes in human metagenomic data by predicting unknown protein families.

Barrientos-Somarribas M, Messina DN, Pou C, ..., Andersson B, Sonnhammer ELL

Sci Rep 8 (1) 28 [2018-01-08; online 2018-01-08]

The role of Cdx2 as a lineage specific transcriptional repressor for pluripotent network during the first developmental cell lineage segregation.

Huang D, Guo G, Yuan P, ..., Robson P, Han X

Sci Rep 7 (1) 17156 [2017-12-07; online 2017-12-07]

STRT-seq-2i: dual-index 5' single cell and nucleus RNA-seq on an addressable microwell array.

Hochgerner H, Lönnerberg P, Hodge R, ..., Zeisel A, Linnarsson S

Sci Rep 7 (1) 16327 [2017-11-27; online 2017-11-27]

HDL particles incorporate into lipid bilayers - a combined AFM and single molecule fluorescence microscopy study.

Plochberger B, Röhrl C, Preiner J, ..., Stangl H, Schütz GJ

Sci Rep 7 (1) 15886 [2017-11-21; online 2017-11-21]

Erdinc Sezgin SciLifeLab Fellow

Dog ownership and the risk of cardiovascular disease and death - a nationwide cohort study.

Mubanga M, Byberg L, Nowak C, ..., Ingelsson E, Fall T

Sci Rep 7 (1) 15821 [2017-11-17; online 2017-11-17]

An exome sequencing based approach for genome-wide association studies in the dog.

Broeckx BJG, Derrien T, Mottier S, ..., Peelman L, Hitte C

Sci Rep 7 (1) 15680 [2017-11-15; online 2017-11-15]

Systems pathology by multiplexed immunohistochemistry and whole-slide digital image analysis.

Blom S, Paavolainen L, Bychkov D, ..., Kallioniemi O, Pellinen T

Sci Rep 7 (1) 15580 [2017-11-14; online 2017-11-14]

Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.

Egaña I, Kaito H, Nitzsche A, ..., Hellström M, German Mouse Clinic Consortium

Sci Rep 7 (1) 15453 [2017-11-13; online 2017-11-13]

Comparative evaluation of tumor targeting using the anti-HER2 ADAPT scaffold protein labeled at the C-terminus with indium-111 or technetium-99m.

Garousi J, Lindbo S, Mitran B, ..., Tolmachev V, Hober S

Sci Rep 7 (1) 14780 [2017-11-07; online 2017-11-07]

Structural variability and complexity of the giant Pithovirus sibericum particle revealed by high-voltage electron cryo-tomography and energy-filtered electron cryo-microscopy.

Okamoto K, Miyazaki N, Song C, ..., Svenda M, Murata K

Sci Rep 7 (1) 13291 [2017-10-16; online 2017-10-16]

Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface.

Flowers SA, Zieba A, Örnros J, ..., Kamali-Moghaddam M, Karlsson NG

Sci Rep 7 (1) 13149 [2017-10-13; online 2017-10-13]

Signatures of positive selection reveal a universal role of chromatin modifiers as cancer driver genes.

Zapata L, Susak H, Drechsel O, ..., Estivill X, Ossowski S

Sci Rep 7 (1) 13124 [2017-10-13; online 2017-10-13]

Affiliated researcher Marc Friedländer SciLifeLab Fellow

Spatial detection of fetal marker genes expressed at low level in adult human heart tissue.

Asp M, Salmén F, Ståhl PL, ..., Linde C, Lundeberg J

Sci Rep 7 (1) 12941 [2017-10-11; online 2017-10-11]

Affiliated researcher Sanja Vickovic SciLifeLab Fellow

Predicting Causal Relationships from Biological Data: Applying Automated Causal Discovery on Mass Cytometry Data of Human Immune Cells.

Triantafillou S, Lagani V, Heinze-Deml C, ..., Tegner J, Tsamardinos I

Sci Rep 7 (1) 12724 [2017-10-05; online 2017-10-05]

Identification and characterization of the novel colonization factor CS30 based on whole genome sequencing in enterotoxigenic Escherichia coli (ETEC).

von Mentzer A, Tobias J, Wiklund G, ..., Sjöling Å, Svennerholm AM

Sci Rep 7 (1) 12514 [2017-10-02; online 2017-10-02]

Astrid von Mentzer DDLS Fellow

Anti-mycobacterial activity correlates with altered DNA methylation pattern in immune cells from BCG-vaccinated subjects.

Verma D, Parasa VR, Raffetseder J, ..., Netea M, Lerm M

Sci Rep 7 (1) 12305 [2017-09-26; online 2017-09-26]

Cerium oxide nanoparticles inhibit differentiation of neural stem cells.

Gliga AR, Edoff K, Caputo F, ..., Ceccatelli S, Fadeel B

Sci Rep 7 (1) 9284 [2017-08-24; online 2017-08-24]

The effect of the TM6SF2 E167K variant on liver steatosis and fibrosis in patients with chronic hepatitis C: a meta-analysis.

Liu Z, Que S, Zhou L, ..., Mardinoglu A, Valenti L

Sci Rep 7 (1) 9273 [2017-08-24; online 2017-08-24]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway.

Reyhani V, Tsioumpekou M, van Wieringen T, ..., Lennartsson J, Rubin K

Sci Rep 7 (1) 8924 [2017-08-21; online 2017-08-21]

Dilution of whisky - the molecular perspective.

Karlsson BCG, Friedman R

Sci Rep 7 (1) 6489 [2017-08-17; online 2017-08-17]

Automated Training of Deep Convolutional Neural Networks for Cell Segmentation.

Sadanandan SK, Ranefall P, Le Guyader S, Wählby C

Sci Rep 7 (1) 7860 [2017-08-10; online 2017-08-10]

Rapid signal enhancement method for nanoprobe-based biosensing.

Dias JT, Svedberg G, Nystrand M, Andersson-Svahn H, Gantelius J

Sci Rep 7 (1) 6837 [2017-07-28; online 2017-07-28]

Translational roles of the C75 2'OH in an in vitro tRNA transcript at the ribosomal A, P and E sites.

Wang J, Forster AC

Sci Rep 7 (1) 6709 [2017-07-27; online 2017-07-27]

Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis.

Nilsson A, Peric A, Strimfors M, ..., Andrén PE, Hilgendorf C

Sci Rep 7 (1) 6352 [2017-07-25; online 2017-07-25]

Fragment optimization for GPCRs by molecular dynamics free energy calculations: Probing druggable subpockets of the A 2A adenosine receptor binding site.

Matricon P, Ranganathan A, Warnick E, ..., Jacobson KA, Carlsson J

Sci Rep 7 (1) 6398 [2017-07-25; online 2017-07-25]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

Novel risk genes for systemic lupus erythematosus predicted by random forest classification.

Almlöf JC, Alexsson A, Imgenberg-Kreuz J, ..., Sandling JK, Syvänen AC

Sci Rep 7 (1) 6236 [2017-07-24; online 2017-07-24]

High performance micro-flow cytometer based on optical fibres.

Etcheverry S, Faridi A, Ramachandraiah H, ..., Laurell F, Russom A

Sci Rep 7 (1) 5628 [2017-07-17; online 2017-07-17]

Selection of complementary foods based on optimal nutritional values.

Sen P, Mardinogulu A, Nielsen J

Sci Rep 7 (1) 5413 [2017-07-14; online 2017-07-14]

Isoelectric point-based fractionation by HiRIEF coupled to LC-MS allows for in-depth quantitative analysis of the phosphoproteome.

Panizza E, Branca RMM, Oliviusson P, Orre LM, Lehtiö J

Sci Rep 7 (1) 4513 [2017-07-03; online 2017-07-03]

SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts.

Stattin EL, Henning P, Klar J, ..., Wikström J, Lerner UH

Sci Rep 7 (1) 3012 [2017-06-07; online 2017-06-07]

Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis.

Abadpour S, Göpel SO, Schive SW, ..., Foss A, Scholz H

Sci Rep 7 (1) 1575 [2017-05-08; online 2017-05-08]

Expression proteomics study to determine metallodrug targets and optimal drug combinations.

Lee RFS, Chernobrovkin A, Rutishauser D, ..., Zubarev RA, Dyson PJ

Sci Rep 7 (1) 1590 [2017-05-08; online 2017-05-08]

Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation.

Padhan N, Yan J, Boge A, ..., Claesson-Welsh L, Landegren U

Sci Rep 7 (1) 1490 [2017-05-04; online 2017-05-04]

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.

Gorski M, van der Most PJ, Teumer A, ..., Böger CA, Fuchsberger C

Sci Rep 7 (-) 45040 [2017-04-28; online 2017-04-28]

A large-scale benchmark of gene prioritization methods.

Guala D, Sonnhammer ELL

Sci Rep 7 (-) 46598 [2017-04-21; online 2017-04-21]

Formal Definitions of Unbounded Evolution and Innovation Reveal Universal Mechanisms for Open-Ended Evolution in Dynamical Systems.

Adams A, Zenil H, Davies PCW, Walker SI

Sci Rep 7 (1) 997 [2017-04-20; online 2017-04-20]

Quantitative humoral profiling of the HIV-1 proteome in elite controllers and patients with very long-term efficient antiretroviral therapy.

Zhang W, Morshed MM, Noyan K, ..., Sönnerborg A, Neogi U

Sci Rep 7 (1) 666 [2017-04-06; online 2017-04-06]

Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia.

Löf L, Arngården L, Olsson-Strömberg U, ..., Landegren U, Kamali-Moghaddam M

Sci Rep 7 (1) 623 [2017-04-04; online 2017-04-04]

Analysis of spatial heterogeneity in normal epithelium and preneoplastic alterations in mouse prostate tumor models.

Valkonen M, Ruusuvuori P, Kartasalo K, ..., Visakorpi T, Latonen L

Sci Rep 7 (-) 44831 [2017-03-20; online 2017-03-20]

DDLS Fellow Kimmo Kartasalo

Discovery of circulating proteins associated to knee radiographic osteoarthritis.

Lourido L, Ayoglu B, Fernández-Tajes J, ..., Nilsson P, Blanco FJ

Sci Rep 7 (1) 137 [2017-03-09; online 2017-03-09]

Immunogenicity is preferentially induced in sparse dendritic cell cultures.

Nasi A, Bollampalli VP, Sun M, ..., Rothfuchs AG, Réthi B

Sci Rep 7 (-) 43989 [2017-03-09; online 2017-03-09]

Emotional anticipation after delivery - a longitudinal neuroimaging study of the postpartum period.

Gingnell M, Toffoletto S, Wikström J, ..., Comasco E, Sundström-Poromaa I

Sci Rep 7 (1) 114 [2017-03-08; online 2017-03-08]

Erika Comasco SciLifeLab Fellow

Epitopes of anti-RIFIN antibodies and characterization of rif-expressing Plasmodium falciparum parasites by RNA sequencing.

Ch'ng JH, Sirel M, Zandian A, ..., Qundos U, Wahlgren M

Sci Rep 7 (-) 43190 [2017-02-24; online 2017-02-24]

Intracellular drug bioavailability: a new predictor of system dependent drug disposition.

Mateus A, Treyer A, Wegler C, ..., Matsson P, Artursson P

Sci Rep 7 (-) 43047 [2017-02-22; online 2017-02-22]

Concomitant underexpression of TGFBR2 and overexpression of hTERT are associated with poor prognosis in cervical cancer.

Yang H, Zhang H, Zhong Y, ..., Zhou F, Zhou Y

Sci Rep 7 (-) 41670 [2017-02-14; online 2017-02-14]

DDLS Fellow Qiaoli Wang

Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging.

Zanni G, Michno W, Di Martino E, ..., Blomgren K, Hanrieder J

Sci Rep 7 (-) 40726 [2017-01-18; online 2017-01-18]

SciLifeLab Fellow Wojciech Michno

New insights into the GINS complex explain the controversy between existing structural models.

Carroni M, De March M, Medagli B, ..., Patwardhan A, Onesti S

Sci Rep 7 (-) 40188 [2017-01-10; online 2017-01-10]

The genome of Rhizobiales bacteria in predatory ants reveals urease gene functions but no genes for nitrogen fixation.

Neuvonen MM, Tamarit D, Näslund K, ..., Guy L, Andersson SG

Sci Rep 6 (-) 39197 [2016-12-15; online 2016-12-15]

Widespread episodic thiamine deficiency in Northern Hemisphere wildlife.

Balk L, Hägerroth PÅ, Gustavsson H, ..., Mörner T, Hansson T

Sci Rep 6 (-) 38821 [2016-12-13; online 2016-12-13]

Allochthonous carbon is a major regulator to bacterial growth and community composition in subarctic freshwaters

Roiha T, Peura S, Cusson M, Rautio M

Sci Rep 6 (1) - [2016-12-00; online 2016-09-30]

Sari Peura SciLifeLab Fellow

Habitat generalists and specialists in microbial communities across a terrestrial-freshwater gradient.

Monard C, Gantner S, Bertilsson S, Hallin S, Stenlid J

Sci Rep 6 (-) 37719 [2016-11-25; online 2016-11-25]

Exploring Spatio-temporal Dynamics of Cellular Automata for Pattern Recognition in Networks.

Miranda GHB, Machicao J, Bruno OM

Sci Rep 6 (-) 37329 [2016-11-22; online 2016-11-22]

Gisele Miranda SciLifeLab Fellow

An automated approach to prepare tissue-derived spatially barcoded RNA-sequencing libraries.

Jemt A, Salmén F, Lundmark A, ..., Yucel-Lindberg T, Lundeberg J

Sci Rep 6 (-) 37137 [2016-11-16; online 2016-11-16]

Rawcopy: Improved copy number analysis with Affymetrix arrays.

Mayrhofer M, Viklund B, Isaksson A

Sci Rep 6 (-) 36158 [2016-10-31; online 2016-10-31]

Mesenchymal state of intimal cells may explain higher propensity to ascending aortic aneurysm in bicuspid aortic valves.

Maleki S, Kjellqvist S, Paloschi V, ..., Eriksson P, Björck HM

Sci Rep 6 (-) 35712 [2016-10-25; online 2016-10-25]

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis.

Loley C, Alver M, Assimes TL, ..., Erdmann J, König IR

Sci Rep 6 (-) 35278 [2016-10-12; online 2016-10-12]

Nematodes join the family of chondroitin sulfate-synthesizing organisms: Identification of an active chondroitin sulfotransferase in Caenorhabditis elegans.

Dierker T, Shao C, Haitina T, ..., Hinas A, Kjellén L

Sci Rep 6 (-) 34662 [2016-10-05; online 2016-10-05]

ProQ3: Improved model quality assessments using Rosetta energy terms.

Uziela K, Shu N, Wallner B, Elofsson A

Sci Rep 6 (-) 33509 [2016-10-04; online 2016-10-04]

Detecting individual extracellular vesicles using a multicolor in situ proximity ligation assay with flow cytometric readout.

Löf L, Ebai T, Dubois L, ..., Landegren U, Kamali-Moghaddam M

Sci Rep 6 (-) 34358 [2016-09-29; online 2016-09-29]

Investigation of rare and low-frequency variants using high-throughput sequencing with pooled DNA samples.

Wang J, Skoog T, Einarsdottir E, ..., Kere J, Jiao H

Sci Rep 6 (-) 33256 [2016-09-16; online 2016-09-16]

Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing.

Ferreira PG, Oti M, Barann M, ..., Guigó R, Sammeth M

Sci Rep 6 (1) 32406 [2016-09-12; online 2016-09-12]

Affiliated researcher Marc Friedländer SciLifeLab Fellow

Enhancing Endosomal Escape for Intracellular Delivery of Macromolecular Biologic Therapeutics.

Lönn P, Kacsinta AD, Cui XS, ..., Gogoi K, Dowdy SF

Sci Rep 6 (-) 32301 [2016-09-08; online 2016-09-08]

The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation.

Schulte T, Mikaelsson C, Beaussart A, ..., Nygren PÅ, Achour A

Sci Rep 6 (-) 32371 [2016-09-01; online 2016-09-01]

Label-free detection of real-time DNA amplification using a nanofluidic diffraction grating.

Yasui T, Ogawa K, Kaji N, ..., Horiike Y, Baba Y

Sci Rep 6 (-) 31642 [2016-08-17; online 2016-08-17]

Stratification of responders towards eculizumab using a structural epitope mapping strategy.

Volk AL, Hu FJ, Berglund MM, ..., Uhlen M, Rockberg J

Sci Rep 6 (-) 31365 [2016-08-11; online 2016-08-11]

Enzyme overexpression - an exercise toward understanding regulation of heparan sulfate biosynthesis.

Fang J, Song T, Lindahl U, Li JP

Sci Rep 6 (-) 31242 [2016-08-11; online 2016-08-11]

ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells.

Wee B, Pietras A, Ozawa T, ..., Michor F, Holland EC

Sci Rep 6 (-) 25956 [2016-07-26; online 2016-07-26]

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation.

Carthy JM, Stöter M, Bellomo C, ..., Heldin CH, Moustakas A

Sci Rep 6 (-) 29868 [2016-07-19; online 2016-07-19]

Exome sequencing in pooled DNA samples to identify maternal pre-eclampsia risk variants.

Kaartokallio T, Wang J, Heinonen S, ..., Kere J, Laivuori H

Sci Rep 6 (-) 29085 [2016-07-07; online 2016-07-07]

Reciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation.

Conti L, Renhorn J, Gabrielsson A, ..., Lindahl E, Elinder F

Sci Rep 6 (-) 27562 [2016-06-09; online 2016-06-09]

Thermotolerant yeasts selected by adaptive evolution express heat stress response at 30 °C.

Caspeta L, Chen Y, Nielsen J

Sci Rep 6 (-) 27003 [2016-05-27; online 2016-05-27]

Conditional Disease Development extracted from Longitudinal Health Care Cohort Data using Layered Network Construction.

Kannan V, Swartz F, Kiani NA, ..., Alexanderson K, Tegnèr J

Sci Rep 6 (-) 26170 [2016-05-23; online 2016-05-23]

The mitogenome of a 35,000-year-old Homo sapiens from Europe supports a Palaeolithic back-migration to Africa.

Hervella M, Svensson EM, Alberdi A, ..., Netea MG, de-la-Rua C

Sci Rep 6 (-) 25501 [2016-05-19; online 2016-05-19]

Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model.

de Boeck M, Cui C, Mulder AA, ..., Ikeno S, Ten Dijke P

Sci Rep 6 (-) 24968 [2016-04-26; online 2016-04-26]

Metagenomic analysis of bloodstream infections in patients with acute leukemia and therapy-induced neutropenia.

Gyarmati P, Kjellander C, Aust C, ..., Öhrmalm L, Giske CG

Sci Rep 6 (-) 23532 [2016-03-21; online 2016-03-21]

Biological insertion of computationally designed short transmembrane segments.

Baeza-Delgado C, von Heijne G, Marti-Renom MA, Mingarro I

Sci Rep 6 (-) 23397 [2016-03-18; online 2016-03-18]

NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis.

Tervaniemi MH, Katayama S, Skoog T, ..., Kere J, Elomaa O

Sci Rep 6 (-) 22745 [2016-03-15; online 2016-03-15]

Bacterial associations reveal spatial population dynamics in Anopheles gambiae mosquitoes.

Buck M, Nilsson LK, Brunius C, ..., Hopkins R, Terenius O

Sci Rep 6 (-) 22806 [2016-03-10; online 2016-03-10]

Whole genome sequencing identifies a novel species of the genus Capnocytophaga isolated from dog and cat bite wounds in humans.

Zangenah S, Abbasi N, Andersson AF, Bergman P

Sci Rep 6 (-) 22919 [2016-03-07; online 2016-03-07]

Cells release subpopulations of exosomes with distinct molecular and biological properties.

Willms E, Johansson HJ, Mäger I, ..., Wood MJ, Vader P

Sci Rep 6 (-) 22519 [2016-03-02; online 2016-03-02]

Metabolic Trade-offs in Yeast are Caused by F1F0-ATP synthase.

Nilsson A, Nielsen J

Sci Rep 6 (-) 22264 [2016-03-01; online 2016-03-01]

Avlant Nilsson DDLS Fellow

GeneiASE: Detection of condition-dependent and static allele-specific expression from RNA-seq data without haplotype information.

Edsgärd D, Iglesias MJ, Reilly SJ, ..., Odeberg J, Emanuelsson O

Sci Rep 6 (-) 21134 [2016-02-18; online 2016-02-18]

Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1.

Landegren N, Sharon D, Freyhult E, ..., Snyder M, Kämpe O

Sci Rep 6 (-) 20104 [2016-02-01; online 2016-02-01]

Knock-down of ZBED6 in insulin-producing cells promotes N-cadherin junctions between beta-cells and neural crest stem cells in vitro.

Wang X, Xie B, Qi Y, ..., Kozlova EN, Welsh N

Sci Rep 6 (-) 19006 [2016-01-11; online 2016-01-11]

Transcriptome analysis reveals mucin 4 to be highly associated with periodontitis and identifies pleckstrin as a link to systemic diseases.

Lundmark A, Davanian H, Båge T, ..., Lundeberg J, Yucel-Lindberg T

Sci Rep 5 (-) 18475 [2015-12-21; online 2015-12-21]

Protein profiling reveals consequences of lifestyle choices on predicted biological aging.

Enroth S, Enroth SB, Johansson Å, Gyllensten U

Sci Rep 5 (-) 17282 [2015-12-01; online 2015-12-01]

Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides

Gosselin-Badaroudine P, Moreau A, Delemotte L, ..., Klein ML, Chahine M

Sci Rep 5 (1) - [2015-12-00; online 2015-07-23]

Lucie Delemotte SciLifeLab Fellow

Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome.

Eakins R, Walsh J, Randle L, ..., Goldring CE, Park BK

Sci Rep 5 (-) 16423 [2015-11-26; online 2015-11-26]

Amelanism in the corn snake is associated with the insertion of an LTR-retrotransposon in the OCA2 gene.

Saenko SV, Lamichhaney S, Martinez Barrio A, ..., Andersson L, Milinkovitch MC

Sci Rep 5 (-) 17118 [2015-11-24; online 2015-11-24]

NPM1 histone chaperone is upregulated in glioblastoma to promote cell survival and maintain nucleolar shape.

Holmberg Olausson K, Elsir T, Moazemi Goudarzi K, Nistér M, Lindström MS

Sci Rep 5 (-) 16495 [2015-11-12; online 2015-11-12]

Single cell analysis of cancer cells using an improved RT-MLPA method has potential for cancer diagnosis and monitoring.

Kvastad L, Werne Solnestam B, Johansson E, ..., Latta D, Lundeberg J

Sci Rep 5 (-) 16519 [2015-11-12; online 2015-11-12]

Domestication Effects on Stress Induced Steroid Secretion and Adrenal Gene Expression in Chickens.

Fallahsharoudi A, de Kock N, Johnsson M, ..., Wright D, Jensen P

Sci Rep 5 (-) 15345 [2015-10-16; online 2015-10-16]

The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation.

Gustafsson Sheppard N, Jarl L, Mahadessian D, ..., Jain M, Nilsson R

Sci Rep 5 (-) 15029 [2015-10-13; online 2015-10-13]

An ace-1 gene duplication resorbs the fitness cost associated with resistance in Anopheles gambiae, the main malaria mosquito.

Assogba BS, Djogbénou LS, Milesi P, ..., Labbé P, Weill M

Sci Rep 5 (-) 14529 [2015-10-05; online 2015-10-05]

Pascal Milesi SciLifeLab Fellow

Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue.

Mardinoglu A, Heiker JT, Gärtner D, ..., Nielsen J, Blüher M

Sci Rep 5 (1) 14841 [2015-10-05; online 2015-10-05]

Gene expression profiling of pre-eclamptic placentae by RNA sequencing.

Kaartokallio T, Cervera A, Kyllönen A, ..., Laivuori H, FINNPEC Core Investigator Group

Sci Rep 5 (-) 14107 [2015-09-21; online 2015-09-21]

Improved canine exome designs, featuring ncRNAs and increased coverage of protein coding genes.

Broeckx BJ, Hitte C, Coopman F, ..., Van Nieuwerburgh F, Deforce D

Sci Rep 5 (-) 12810 [2015-08-03; online 2015-08-03]

Compaction of rolling circle amplification products increases signal integrity and signal-to-noise ratio.

Clausson CM, Arngården L, Ishaq O, ..., Wählby C, Söderberg O

Sci Rep 5 (-) 12317 [2015-07-23; online 2015-07-23]

Promoter-level expression clustering identifies time development of transcriptional regulatory cascades initiated by ErbB receptors in breast cancer cells.

Mina M, Magi S, Jurman G, ..., Okada-Hatakeyama M, Furlanello C

Sci Rep 5 (-) 11999 [2015-07-16; online 2015-07-16]

Metagenomic insights into strategies of aerobic and anaerobic carbon and nitrogen transformation in boreal lakes.

Peura S, Sinclair L, Bertilsson S, Eiler A

Sci Rep 5 (1) 12102 [2015-07-10; online 2015-07-10]

Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome.

Gu Urban GJ, Friedman M, Ren P, ..., Landegren U, Kamali-Moghaddam M

Sci Rep 5 (-) 11196 [2015-06-16; online 2015-06-16]

The T cell receptor resides in ordered plasma membrane nanodomains that aggregate upon patching of the receptor.

Dinic J, Riehl A, Adler J, Parmryd I

Sci Rep 5 (-) 10082 [2015-05-08; online 2015-05-08]

CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells.

Ratz M, Testa I, Hell SW, Jakobs S

Sci Rep 5 (1) 9592 [2015-04-20; online 2015-04-20]

Ilaria Testa SciLifeLab Fellow

No difference in small bowel microbiota between patients with irritable bowel syndrome and healthy controls.

Dlugosz A, Winckler B, Lundin E, ..., Engstrand L, Lindberg G

Sci Rep 5 (-) 8508 [2015-02-17; online 2015-02-17]

System-wide analysis of the transcriptional network of human myelomonocytic leukemia cells predicts attractor structure and phorbol-ester-induced differentiation and dedifferentiation transitions.

Sakata K, Ohyanagi H, Sato S, ..., Suzuki H, Saito T

Sci Rep 5 (-) 8283 [2015-02-06; online 2015-02-06]

Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling.

Ghaffari P, Mardinoglu A, Asplund A, ..., Uhlen M, Nielsen J

Sci Rep 5 (1) 8183 [2015-02-02; online 2015-02-02]

Rational design and validation of a Tip60 histone acetyltransferase inhibitor.

Gao C, Bourke E, Scobie M, ..., Lowndes NF, Brown JA

Sci Rep 4 (-) 5372 [2014-06-20; online 2014-06-20]

Comprehensive profiling of the vaginal microbiome in HIV positive women using massive parallel semiconductor sequencing.

Ameur A, Meiring TL, Bunikis I, ..., Williamson AL, Gyllensten U

Sci Rep 4 (-) 4398 [2014-03-18; online 2014-03-18]

Understanding the interactions between bacteria in the human gut through metabolic modeling

Shoaie S, Karlsson F, Mardinoglu A, ..., Bordel S, Nielsen J

Sci Rep 3 (1) - [2013-12-00; online 2013-08-28]

Adil Mardinoglu SciLifeLab Fellow

The network organization of cancer-associated protein complexes in human tissues.

Zhao J, Lee SH, Huss M, Holme P

Sci Rep 3 (-) 1583 [2013-04-10; online 2013-04-10]

Hierarchical molecular tagging to resolve long continuous sequences by massively parallel sequencing.

Lundin S, Gruselius J, Nystedt B, ..., Käller M, Lundeberg J

Sci Rep 3 (-) 1186 [2013-03-09; online 2013-03-09]

Targeted transcript profiling by sequencing.

Zajac P, Ahmadian A

Sci Rep 2 (-) 821 [2012-11-08; online 2012-11-08]

A novel mutation in the Lipase H gene underlies autosomal recessive hypotrichosis and woolly hair.

Tariq M, Azhar A, Baig SM, Dahl N, Klar J

Sci Rep 2 (-) 730 [2012-10-12; online 2012-10-12]

Multiplex epitope mapping using bacterial surface display reveals both linear and conformational epitopes.

Hudson EP, Uhlen M, Rockberg J

Sci Rep 2 (1) 706 [2012-10-04; online 2012-10-04]