Metabolite Depletion Affects Flux Profiling of Cell Lines.

JSON

Nilsson A, Haanstra JR, Teusink B, Nielsen J

Trends Biochem. Sci. 43 (6) 395-397 [2018-06-00; online 2018-04-12]

Quantifying the rate of consumption and release of metabolites (i.e., flux profiling) has become integral to the study of cancer. The fluxes as well as the growth of the cells may be affected by metabolite depletion during cultivation.

Avlant Nilsson

DDLS Fellow

PubMed 29656822

DOI 10.1016/j.tibs.2018.03.009

Crossref 10.1016/j.tibs.2018.03.009

pii: S0968-0004(18)30063-X