Abhishek Niroula

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Primary: Shown in the list of current labels.

Year 2023

PubMed DOI Crossref
SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation.
Chen CW, Zhang L, Dutta R, ..., Sperling AS, Goodell MA
Cell Stem Cell 30 (11) 1503-1519.e8 [2023-11-02; online 2023-10-19]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Functional and molecular profiling of hematopoietic stem cells during regeneration.
Rydström A, Grahn THM, Niroula A, ..., Larsson J, Karlsson S
Exp. Hematol. 127 (-) 40-51 [2023-11-00; online 2023-09-04]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.
Yu Z, Fidler TP, Ruan Y, ..., Tall AR, Natarajan P
J. Clin. Invest. 133 (18) - [2023-09-15; online 2023-09-15]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Birth Weight Is Associated With Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Outcomes in Adulthood.
Schuermans A, Nakao T, Ruan Y, ..., Natarajan P, Honigberg MC
J Am Heart Assoc 12 (13) e030220 [2023-07-04; online 2023-06-22]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
HLA Class I Genotype Is Associated with Relapse Risk after Allogeneic Stem Cell Transplantation for NPM1-Mutated Acute Myeloid Leukemia.
Narayan R, Niroula A, Wang T, ..., Spellman S, Lee SJ
Transplant Cell Ther 29 (7) 452.e1-452.e11 [2023-07-00; online 2023-03-29]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Obesity-induced inflammation exacerbates clonal hematopoiesis.
Pasupuleti SK, Ramdas B, Burns SS, ..., Natarajan P, Kapur R
J. Clin. Invest. 133 (11) - [2023-06-01; online 2023-06-01]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Clonal Hematopoiesis of Indeterminate Potential Predicts Adverse Outcomes in Patients With Atherosclerotic Cardiovascular Disease.
Gumuser ED, Schuermans A, Cho SMJ, ..., Natarajan P, Honigberg MC
J. Am. Coll. Cardiol. 81 (20) 1996-2009 [2023-05-23; online 2023-05-18]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic data sets.
Vlasschaert C, Mack T, Heimlich JB, ..., Jaiswal S, Bick AG
Blood 141 (18) 2214-2223 [2023-05-04; online 2023-01-19]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Prediction of risk for myeloid malignancy in clonal hematopoiesis.
Weeks LD, Niroula A, Neuberg D, ..., Natarajan P, Ebert BL
NEJM Evid 2 (5) - [2023-05-00; online 2023-04-25]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Clonal haematopoiesis and risk of chronic liver disease.
Wong WJ, Emdin C, Bick AG, ..., Ebert BL, Natarajan P
Nature 616 (7958) 747-754 [2023-04-00; online 2023-04-12]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Clonal Hematopoiesis and Risk of Incident Lung Cancer.
Tian R, Wiley B, Liu J, ..., Bolton KL, Cao Y
J Clin Oncol 41 (7) 1423-1433 [2023-03-01; online 2022-12-08]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
TP53-mediated clonal hematopoiesis confers increased risk for incident atherosclerotic disease.
Zekavat SM, Viana-Huete V, Matesanz N, ..., Fuster JJ, Klarin D
Nat Cardiovasc Res 2 (-) 144-158 [2023-01-16; online 2023-03-24]
Abhishek Niroula DDLS Fellow

Year 2022

PubMed DOI Crossref
TET2-mutant clonal hematopoiesis and risk of gout.
Agrawal M, Niroula A, Cunin P, ..., Rao DA, Ebert BL
Blood 140 (10) 1094-1103 [2022-09-08; online 2022-06-18]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Genetics of smoking and risk of clonal hematopoiesis.
Levin MG, Nakao T, Zekavat SM, ..., Damrauer SM, Natarajan P
Sci Rep 12 (1) 7248 [2022-05-04; online 2022-05-04]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Clonal Hematopoiesis and CKD Progression.
Niroula A, Belizaire R
J. Am. Soc. Nephrol. 33 (5) 878-879 [2022-05-00; online 2022-04-06]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.
Nakao T, Bick AG, Taub MA, ..., NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium , Natarajan P
Sci Adv 8 (14) eabl6579 [2022-04-08; online 2022-04-06]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Genome-wide association study on 13 167 individuals identifies regulators of blood CD34+cell levels.
Lopez de Lapuente Portilla A, Ekdahl L, Cafaro C, ..., Stefansson K, Nilsson B
Blood 139 (11) 1659-1669 [2022-03-17; online 2022-01-11]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Clonal Hematopoiesis Is Associated With Higher Risk of Stroke.
Bhattacharya R, Zekavat SM, Haessler J, ..., Natarajan P, Reiner AP
Stroke 53 (3) 788-797 [2022-03-00; online 2021-11-08]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Association of clonal hematopoiesis with chronic obstructive pulmonary disease.
Miller PG, Qiao D, Rojas-Quintero J, ..., Ebert BL, COPDGene Study Investigators, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine Consortium
Blood 139 (3) 357-368 [2022-01-20; online 2021-12-03]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Functional dissection of inherited non-coding variation influencing multiple myeloma risk.
Ajore R, Niroula A, Pertesi M, ..., Houlston R, Nilsson B
Nat Commun 13 (1) 151 [2022-01-10; online 2022-01-10]
Abhishek Niroula DDLS Fellow

Year 2021

PubMed DOI Crossref
Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis.
Kim PG, Niroula A, Shkolnik V, ..., Natarajan P, Ebert BL
J. Exp. Med. 218 (12) - [2021-12-06; online 2021-10-26]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Distinction of lymphoid and myeloid clonal hematopoiesis.
Niroula A, Sekar A, Murakami MA, ..., Natarajan P, Ebert BL
Nat. Med. 27 (11) 1921-1927 [2021-11-00; online 2021-10-18]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Association of Diet Quality With Prevalence of Clonal Hematopoiesis and Adverse Cardiovascular Events.
Bhattacharya R, Zekavat SM, Uddin MM, ..., Bick A, Natarajan P
JAMA Cardiol 6 (9) 1069-1077 [2021-09-01; online 2021-06-10]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
ZBTB33 is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing.
Beauchamp EM, Leventhal M, Bernard E, ..., Jaiswal S, Ebert BL
Blood Cancer Discov 2 (5) 500-517 [2021-09-00; online 2021-07-14]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure.
Yu B, Roberts MB, Raffield LM, ..., Eaton CB, National Heart, Lung, and Blood Institute TOPMed Consortium
J. Am. Coll. Cardiol. 78 (1) 42-52 [2021-07-06; online 2021-07-03]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Prognostic implications of troponin T variations in inherited cardiomyopathies using systems biology.
Shakur R, Ochoa JP, Robinson AJ, ..., Vihinen M, Monserrat L
NPJ Genom Med 6 (1) 47 [2021-06-14; online 2021-06-14]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Germline variants at SOHLH2 influence multiple myeloma risk.
Duran-Lozano L, Thorleifsson G, Lopez de Lapuente Portilla A, ..., Stefansson K, Nilsson B
Blood Cancer J 11 (4) 76 [2021-04-19; online 2021-04-19]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes.
Bick AG, Weinstock JS, Nandakumar SK, ..., Kathiresan S, Natarajan P
Nature 591 (7851) E27 [2021-03-00; online 2021-03-13]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Accelerating target deconvolution for therapeutic antibody candidates using highly parallelized genome editing.
Mattsson J, Ekdahl L, Junghus F, ..., Teige I, Nilsson B
Nat Commun 12 (1) 1277 [2021-02-24; online 2021-02-24]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women.
Honigberg MC, Zekavat SM, Niroula A, ..., NHLBI Trans-Omics for Precision Medicine Program , Natarajan P
Circulation 143 (5) 410-423 [2021-02-02; online 2020-11-09]
Abhishek Niroula DDLS Fellow

Year 2020

PubMed DOI Crossref
S100A6 is a critical regulator of hematopoietic stem cells.
Grahn THM, Niroula A, Végvári Á, ..., Zubarev RA, Karlsson S
Leukemia 34 (12) 3323-3337 [2020-12-00; online 2020-06-19]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Identification of germline variants in adults with hemophagocytic lymphohistiocytosis.
Miller PG, Niroula A, Ceremsak JJ, ..., Berliner N, Ebert BL
Blood Adv 4 (5) 925-929 [2020-03-10; online 2020-03-10]
Abhishek Niroula DDLS Fellow

Year 2019

PubMed DOI Crossref
MPRAscore: robust and non-parametric analysis of massively parallel reporter assays.
Niroula A, Ajore R, Nilsson B
Bioinformatics 35 (24) 5351-5353 [2019-12-15; online 2019-07-31]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
ProTstab - predictor for cellular protein stability.
Yang Y, Ding X, Zhu G, ..., Lv Q, Vihinen M
BMC Genomics 20 (1) 804 [2019-11-04; online 2019-11-04]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
How good are pathogenicity predictors in detecting benign variants?
Niroula A, Vihinen M
PLoS Comput Biol 15 (2) e1006481 [2019-02-00; online 2019-02-11]
Abhishek Niroula DDLS Fellow

Year 2018

PubMed DOI Crossref
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression.
Ali M, Ajore R, Wihlborg AK, ..., Weinhold N, Nilsson B
Nat Commun 9 (1) 1649 [2018-04-25; online 2018-04-25]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
PON-tstab: Protein Variant Stability Predictor. Importance of Training Data Quality.
Yang Y, Urolagin S, Niroula A, ..., Shen B, Vihinen M
Int J Mol Sci 19 (4) - [2018-03-28; online 2018-03-28]
Abhishek Niroula DDLS Fellow

Year 2017

PubMed DOI Crossref
Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges.
Daneshjou R, Wang Y, Bromberg Y, ..., Brenner SE, Morgan AA
Hum. Mutat. 38 (9) 1182-1192 [2017-09-00; online 2017-07-07]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI.
Carraro M, Minervini G, Giollo M, ..., Moult J, Tosatto SCE
Hum. Mutat. 38 (9) 1042-1050 [2017-09-00; online 2017-05-16]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
PON-P and PON-P2 predictor performance in CAGI challenges: Lessons learned.
Niroula A, Vihinen M
Hum. Mutat. 38 (9) 1085-1091 [2017-09-00; online 2017-05-02]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Direct evidence for a polygenic etiology in familial multiple myeloma.
Halvarsson BM, Wihlborg AK, Ali M, ..., Hansson M, Nilsson B
Blood Adv 1 (10) 619-623 [2017-04-11; online 2017-04-07]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Predicting Severity of Disease-Causing Variants.
Niroula A, Vihinen M
Hum. Mutat. 38 (4) 357-364 [2017-04-00; online 2017-01-24]
Abhishek Niroula DDLS Fellow

Year 2016

PubMed DOI Crossref
PON-Sol: prediction of effects of amino acid substitutions on protein solubility.
Yang Y, Niroula A, Shen B, Vihinen M
Bioinformatics 32 (13) 2032-2034 [2016-07-01; online 2016-02-19]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Variation Interpretation Predictors: Principles, Types, Performance, and Choice.
Niroula A, Vihinen M
Hum. Mutat. 37 (6) 579-597 [2016-06-00; online 2016-04-15]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
PON-mt-tRNA: a multifactorial probability-based method for classification of mitochondrial tRNA variations.
Niroula A, Vihinen M
Nucleic Acids Res. 44 (5) 2020-2027 [2016-03-18; online 2016-02-03]
Abhishek Niroula DDLS Fellow

Year 2015

PubMed DOI Crossref
Classification of Amino Acid Substitutions in Mismatch Repair Proteins Using PON-MMR2.
Niroula A, Vihinen M
Hum. Mutat. 36 (12) 1128-1134 [2015-12-00; online 2015-09-22]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Harmful somatic amino acid substitutions affect key pathways in cancers.
Niroula A, Vihinen M
BMC Med Genomics 8 (-) 53 [2015-08-19; online 2015-08-19]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
PON-P2: prediction method for fast and reliable identification of harmful variants.
Niroula A, Urolagin S, Vihinen M
PLoS ONE 10 (2) e0117380 [2015-02-03; online 2015-02-03]
Abhishek Niroula DDLS Fellow
SciLifeLab Data Centre
Publications 9.5.1