Giedraitis V

Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.

Keaton JM, Kamali Z, Xie T, ..., Snieder H, Warren HR

Nat. Genet. 56 (5) 778-791 [2024-05-00; online 2024-04-30]

The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation.

Pagnon de la Vega M, Giedraitis V, Michno W, ..., Sehlin D, Ingelsson M

Sci Transl Med 13 (606) - [2021-08-11; online 2021-08-13]

SciLifeLab Fellow Wojciech Michno

Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V, Mägi R, Hottenga JJ, ..., Prokopenko I, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)

Nat Commun 12 (1) 995 [2021-02-08; online 2021-02-08]

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V, Mägi R, Hottenga JJ, ..., Prokopenko I, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)

Nat Commun 12 (1) 24 [2021-01-05; online 2021-01-05]

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.

Folkersen L, Gustafsson S, Wang Q, ..., Ingelsson E, Mälarstig A

Nat Metab 2 (10) 1135-1148 [2020-10-00; online 2020-10-16]

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.

Ntalla I, Weng LC, Cartwright JH, ..., Lubitz SA, Munroe PB

Nat Commun 11 (1) 2542 [2020-05-21; online 2020-05-21]

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

Shah S, Henry A, Roselli C, ..., Swerdlow DI, Lumbers RT

Nat Commun 11 (1) 163 [2020-01-09; online 2020-01-09]

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.

Tin A, Marten J, Halperin Kuhns VL, ..., Vitart V, Köttgen A

Nat. Genet. 51 (10) 1459-1474 [2019-10-00; online 2019-10-02]

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.

Teumer A, Li Y, Ghasemi S, ..., Pattaro C, Köttgen A

Nat Commun 10 (1) 4130 [2019-09-11; online 2019-09-11]

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

Ntalla I, Weng LC, Cartwright JH, ..., Lubitz SA, Munroe PB

- - (-) - [2019-07-24; online 2019-07-24]

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Wuttke M, Li Y, Li M, ..., Köttgen A, Pattaro C

Nat. Genet. 51 (6) 957-972 [2019-06-00; online 2019-05-31]

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Justice AE, Karaderi T, Highland HM, ..., T2D-Genes Consortium , MAGIC Investigators

Nat. Genet. 51 (3) 452-469 [2019-03-00; online 2019-02-18]

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.

Morris AP, Le TH, Wu H, ..., Humphreys BD, Franceschini N

Nat Commun 10 (1) 29 [2019-01-03; online 2019-01-03]

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Evangelou E, Warren HR, Mosen-Ansorena D, ..., Elliott P, Caulfield MJ

Nat. Genet. 50 (12) 1755 [2018-12-00; online 2018-11-16]

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Evangelou E, Warren HR, Mosen-Ansorena D, ..., Caulfield MJ, Million Veteran Program

Nat. Genet. 50 (10) 1412-1425 [2018-10-00; online 2018-09-17]

Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance.

Nowak C, Hetty S, Salihovic S, ..., Fall T, Ingelsson E

Sci Rep 8 (1) 8691 [2018-06-06; online 2018-06-06]

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Flannick J, Fuchsberger C, Mahajan A, ..., Boehnke M, McCarthy MI

Sci Data 4 (-) 170179 [2017-12-19; online 2017-12-19]