Wojciech Michno (30 publications)

Primary: Shown in the list of current labels.

Year 2024

PubMed DOI Crossref

Chemical signatures delineate heterogeneous amyloid plaque populations across the Alzheimer's disease spectrum.

Koutarapu S, Ge J, Dulewicz M, ..., Schöll M, Hanrieder J

bioRxiv - (-) - [2024-06-03; online 2024-06-03]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Spatial Neurolipidomics at the Single Amyloid-β Plaque Level in Postmortem Human Alzheimer's Disease Brain.

Michno W, Bowman A, Jha D, ..., Heeren RMA, Hanrieder J

ACS Chem Neurosci 15 (4) 877-888 [2024-02-21; online 2024-02-01]

SciLifeLab Fellow Wojciech Michno

Year 2023

PubMed DOI Crossref

Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis.

Qu F, Brough SC, Michno W, ..., Pasca AM, Sage J

Nat. Cell Biol. 25 (10) 1506-1519 [2023-10-00; online 2023-10-02]

SciLifeLab Fellow Wojciech Michno

DOI Crossref

Adrenomedullin promotes interneuron migration in a dual human model for hypoxic interneuronopathy of prematurity

Michno WP, Puno A, Li L, ..., Willsey AJ, Pasca AM

- - (-) - [2023-05-01; online 2023-05-01]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Correlative Chemical Imaging and Spatial Chemometrics Delineate Alzheimer Plaque Heterogeneity at High Spatial Resolution.

Wehrli PM, Ge J, Michno W, ..., Blennow K, Hanrieder J

JACS Au 3 (3) 762-774 [2023-03-27; online 2023-03-07]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells.

Hsu J, Fatuzzo N, Weng N, ..., Nasca C, Khosla C

J Biol Chem 299 (2) 102848 [2023-02-00; online 2022-12-30]

SciLifeLab Fellow Wojciech Michno

Year 2022

PubMed DOI Crossref

Chemical traits of cerebral amyloid angiopathy in familial British-, Danish-, and non-Alzheimer's dementias.

Michno W, Koutarapu S, Camacho R, ..., Lashley T, Hanrieder J

J. Neurochem. 163 (3) 233-246 [2022-11-00; online 2022-09-25]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Correlative Chemical Imaging Identifies Amyloid Peptide Signatures of Neuritic Plaques and Dystrophy in Human Sporadic Alzheimer's Disease.

Koutarapu S, Ge J, Jha D, ..., Michno W, Hanrieder J

Brain Connect - (-) - [2022-10-07; online 2022-10-07]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Structural amyloid plaque polymorphism is associated with distinct lipid accumulations revealed by trapped ion mobility mass spectrometry imaging.

Michno W, Wehrli PM, Koutarapu S, ..., Hopf C, Hanrieder J

J. Neurochem. 160 (4) 482-498 [2022-02-00; online 2021-12-26]

SciLifeLab Fellow Wojciech Michno

Year 2021

PubMed DOI Crossref

Herpes Simplex Virus 1 and 2 Infections during Differentiation of Human Cortical Neurons.

Bergström P, Trybala E, Eriksson CE, ..., Zetterberg H, Bergström T

Viruses 13 (10) - [2021-10-14; online 2021-10-14]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Refining the amyloid β peptide and oligomer fingerprint ambiguities in Alzheimer's disease: Mass spectrometric molecular characterization in brain, cerebrospinal fluid, blood, and plasma.

Michno W, Blennow K, Zetterberg H, Brinkmalm G

J. Neurochem. 159 (2) 234-257 [2021-10-00; online 2021-07-27]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation.

Pagnon de la Vega M, Giedraitis V, Michno W, ..., Sehlin D, Ingelsson M

Sci Transl Med 13 (606) - [2021-08-11; online 2021-08-13]

SciLifeLab Fellow Wojciech Michno

DOI Crossref

Neuronal mimicry generates an ecosystem critical for brain metastatic growth of SCLC

Qu F, Cao S, Michno W, ..., Paşca AM, Sage J

- - (-) - [2021-08-10; online 2021-08-10]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Following spatial Aβ aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics.

Michno W, Stringer KM, Enzlein T, ..., Edwards FA, Hanrieder J

Sci Adv 7 (25) - [2021-06-00; online 2021-06-16]

SciLifeLab Fellow Wojciech Michno

Year 2020

PubMed DOI Crossref

Computational Analysis of Alzheimer Amyloid Plaque Composition in 2D- and Elastically Reconstructed 3D-MALDI MS Images.

Enzlein T, Cordes J, Munteanu B, ..., Chávez-Gutiérrez L, Hopf C

Anal. Chem. 92 (21) 14484-14493 [2020-11-03; online 2020-10-14]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Chemical imaging of evolving amyloid plaque pathology and associated Aβ peptide aggregation in a transgenic mouse model of Alzheimer's disease.

Michno W, Wehrli P, Meier SR, ..., Blennow K, Hanrieder J

J. Neurochem. 152 (5) 602-616 [2020-03-00; online 2019-11-06]

SciLifeLab Fellow Wojciech Michno

Year 2019

PubMed DOI Crossref

Molecular imaging mass spectrometry for probing protein dynamics in neurodegenerative disease pathology.

Michno W, Wehrli PM, Blennow K, Zetterberg H, Hanrieder J

J. Neurochem. 151 (4) 488-506 [2019-11-00; online 2018-11-06]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Chemometric Strategies for Sensitive Annotation and Validation of Anatomical Regions of Interest in Complex Imaging Mass Spectrometry Data.

Wehrli PM, Michno W, Blennow K, Zetterberg H, Hanrieder J

J. Am. Soc. Mass Spectrom. 30 (11) 2278-2288 [2019-11-00; online 2019-09-16]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Association of PTHrP levels in CSF with Alzheimer's disease biomarkers.

Kushnir MM, Michno W, Rockwood AL, ..., Strathmann FG, Hanrieder J

Clin Mass Spectrom 14 Pt B (-) 124-129 [2019-11-00; online 2018-10-09]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Amyloid fibril polymorphism and cell-specific toxicity in vivo.

Jonson M, Nyström S, Sandberg A, ..., Thor S, Hammarström P

Amyloid 26 (sup1) 136-137 [2019-07-26; online 2019-07-26]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

GM1 locates to mature amyloid structures implicating a prominent role for glycolipid-protein interactions in Alzheimer pathology.

Michno W, Wehrli PM, Zetterberg H, Blennow K, Hanrieder J

Biochim Biophys Acta Proteins Proteom 1867 (5) 458-467 [2019-05-00; online 2018-09-28]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology.

Michno W, Nyström S, Wehrli P, ..., Zetterberg H, Hanrieder J

J Biol Chem 294 (17) 6719-6732 [2019-04-26; online 2019-02-27]

SciLifeLab Fellow Wojciech Michno

Year 2018

PubMed DOI Crossref

Multimodal Chemical Imaging of Amyloid Plaque Polymorphism Reveals Aβ Aggregation Dependent Anionic Lipid Accumulations and Metabolism.

Michno W, Kaya I, Nyström S, ..., Zetterberg H, Hanrieder J

Anal. Chem. 90 (13) 8130-8138 [2018-07-03; online 2018-06-19]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Aggregated Aβ1-42 Is Selectively Toxic for Neurons, Whereas Glial Cells Produce Mature Fibrils with Low Toxicity in Drosophila.

Jonson M, Nyström S, Sandberg A, ..., Thor S, Hammarström P

Cell Chem Biol 25 (5) 595-610.e5 [2018-05-17; online 2018-04-12]

SciLifeLab Fellow Wojciech Michno

Year 2017

PubMed DOI Crossref

Novel Trimodal MALDI Imaging Mass Spectrometry (IMS3) at 10 μm Reveals Spatial Lipid and Peptide Correlates Implicated in Aβ Plaque Pathology in Alzheimer's Disease.

Kaya I, Brinet D, Michno W, ..., Blenow K, Hanrieder J

ACS Chem Neurosci 8 (12) 2778-2790 [2017-12-20; online 2017-10-04]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

MALDI imaging delineates hippocampal glycosphingolipid changes associated with neurotoxin induced proteopathy following neonatal BMAA exposure.

Karlsson O, Michno W, Ransome Y, Hanrieder J

Biochim Biophys Acta Proteins Proteom 1865 (7) 740-746 [2017-07-00; online 2016-12-09]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Histology-Compatible MALDI Mass Spectrometry Based Imaging of Neuronal Lipids for Subsequent Immunofluorescent Staining.

Kaya I, Michno W, Brinet D, ..., Zetterberg H, Hanrieder J

Anal. Chem. 89 (8) 4685-4694 [2017-04-18; online 2017-04-06]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Delineating Amyloid Plaque Associated Neuronal Sphingolipids in Transgenic Alzheimer's Disease Mice (tgArcSwe) Using MALDI Imaging Mass Spectrometry.

Kaya I, Brinet D, Michno W, ..., Blennow K, Hanrieder J

ACS Chem Neurosci 8 (2) 347-355 [2017-02-15; online 2017-01-10]

SciLifeLab Fellow Wojciech Michno

PubMed DOI Crossref

Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging.

Zanni G, Michno W, Di Martino E, ..., Blomgren K, Hanrieder J

Sci Rep 7 (-) 40726 [2017-01-18; online 2017-01-18]

SciLifeLab Fellow Wojciech Michno

Year 2016

PubMed DOI Crossref

Probing amyloid-β pathology in transgenic Alzheimer's disease (tgArcSwe) mice using MALDI imaging mass spectrometry.

Carlred L, Michno W, Kaya I, ..., Syvänen S, Hanrieder J

J. Neurochem. 138 (3) 469-478 [2016-08-00; online 2016-05-26]

SciLifeLab Fellow Wojciech Michno