Bick AG

JAK2-mutant clonal hematopoiesis is associated with venous thromboembolism.

Zon RL, Sekar A, Clapham K, ..., Natarajan P, Ebert BL

Blood 144 (20) 2149-2154 [2024-11-14; online 2024-08-05]

Abhishek Niroula DDLS Fellow

Long-term longitudinal analysis of 4,187 participants reveals insights into determinants of clonal hematopoiesis.

Uddin MM, Saadatagah S, Niroula A, ..., Ballantyne CM, Natarajan P

Nat Commun 15 (1) 7858 [2024-09-09; online 2024-09-09]

Abhishek Niroula DDLS Fellow

Atrial Fibrillation and Clonal Hematopoiesis in TET2 and ASXL1.

Saadatagah S, Naderian M, Uddin M, ..., Kullo IJ, Ballantyne CM

JAMA Cardiol 9 (6) 497-506 [2024-06-01; online 2024-04-10]

Abhishek Niroula DDLS Fellow

Clonal Hematopoiesis of Indeterminate Potential With Loss of Tet2 Enhances Risk for Atrial Fibrillation Through Nlrp3 Inflammasome Activation.

Lin AE, Bapat AC, Xiao L, ..., Ellinor PT, Ebert BL

Circulation 149 (18) 1419-1434 [2024-04-30; online 2024-02-15]

Abhishek Niroula DDLS Fellow

SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation.

Chen CW, Zhang L, Dutta R, ..., Sperling AS, Goodell MA

Cell Stem Cell 30 (11) 1503-1519.e8 [2023-11-02; online 2023-10-19]

Abhishek Niroula DDLS Fellow

Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.

Yu Z, Fidler TP, Ruan Y, ..., Tall AR, Natarajan P

J. Clin. Invest. 133 (18) - [2023-09-15; online 2023-09-15]

Abhishek Niroula DDLS Fellow

Birth Weight Is Associated With Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Outcomes in Adulthood.

Schuermans A, Nakao T, Ruan Y, ..., Natarajan P, Honigberg MC

J Am Heart Assoc 12 (13) e030220 [2023-07-04; online 2023-06-22]

Abhishek Niroula DDLS Fellow

Genetics of smoking and risk of clonal hematopoiesis.

Levin MG, Nakao T, Zekavat SM, ..., Damrauer SM, Natarajan P

Sci Rep 12 (1) 7248 [2022-05-04; online 2022-05-04]

Abhishek Niroula DDLS Fellow

Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.

Nakao T, Bick AG, Taub MA, ..., NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium , Natarajan P

Sci Adv 8 (14) eabl6579 [2022-04-08; online 2022-04-06]

Abhishek Niroula DDLS Fellow

Clonal Hematopoiesis Is Associated With Higher Risk of Stroke.

Bhattacharya R, Zekavat SM, Haessler J, ..., Natarajan P, Reiner AP

Stroke 53 (3) 788-797 [2022-03-00; online 2021-11-08]

Abhishek Niroula DDLS Fellow

Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis.

Kim PG, Niroula A, Shkolnik V, ..., Natarajan P, Ebert BL

J. Exp. Med. 218 (12) - [2021-12-06; online 2021-10-26]

Abhishek Niroula DDLS Fellow

ZBTB33 is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing.

Beauchamp EM, Leventhal M, Bernard E, ..., Jaiswal S, Ebert BL

Blood Cancer Discov 2 (5) 500-517 [2021-09-00; online 2021-07-14]

Abhishek Niroula DDLS Fellow