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Gómez de la Torre TZ, Herthnek D, Strømme M
j nanosci nanotechnol 17 (4) 2861-2864 [2017-04-00; online 2018-04-19]
The presented measurement and data analysis procedure reduces the read-out time for the volume-amplified magnetic nanobead detection assay from ~30 min to only 2 min, providing fast, sensitive detection of DNA molecules. The molecular detection and amplification protocol was verified using samples containing rolling circle-amplified DNA products formed from synthetic Vibrio cholerae target DNA, with a limit of detection of 5 pM. The developed read-out method could be used to rapidly identify pathogens in a variety of applications including target screening in hospitals with limited resources, in out-patient settings and in the field.
PubMed 29668218
DOI 10.1166/jnn.2017.13877
Crossref 10.1166/jnn.2017.13877