Merino LG

Intrinsic deletion at 10q23.31, including the PTEN gene locus, is aggravated upon CRISPR-Cas9-mediated genome engineering in HAP1 cells mimicking cancer profiles.

Geng K, Merino LG, Veiga RG, ..., Brinkman EK, Kutter C

Life Sci. Alliance 7 (2) - [2024-02-00; online 2023-11-20]

Claudia Kutter SciLifeLab Fellow

CRISPR-Cas9-mediated genome engineering exaggerates genomic deletion at 10q23.31 including the<i>PTEN</i>gene locus mimicking cancer profiles

Geng K, Merino LG, Veiga RG, ..., Brinkman EK, Kutter C

- - (-) - [2023-04-06; online 2023-04-06]

Claudia Kutter SciLifeLab Fellow

Target-enriched nanopore sequencing and de novo assembly reveals co-occurrences of complex on-target genomic rearrangements induced by CRISPR-Cas9 in human cells.

Geng K, Merino LG, Wedemann L, ..., White RJ, Kutter C

Genome Res 32 (10) 1876-1891 [2022-10-00; online 2022-09-30]

Claudia Kutter SciLifeLab Fellow