J. Biol. Chem.

ISSN	1067-8816
ISSN-L	0021-9258
IUID	e0579db52b7540b184d02bc487f66acc
Modified	2020-11-27T13:12:52.182Z
Created	2018-12-03T14:24:55.362Z

Year 2019

PubMed DOI Crossref

Nanoscale dynamics of cholesterol in the cell membrane.

Pinkwart K, Schneider F, Lukoseviciute M, ..., Eggeling C, Sezgin E

J. Biol. Chem. 294 (34) 12599-12609 [2019-08-23; online 2019-07-03]

Erdinc Sezgin SciLifeLab Fellow

Year 2018

PubMed DOI Crossref

Membrane protein serendipity.

von Heijne G

J. Biol. Chem. 293 (10) 3470-3476 [2018-03-09; online 2018-03-11]

Affiliated researcher

Year 2017

PubMed DOI Crossref

TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation.

Nakano N, Tsuchiya Y, Kako K, ..., Ten Dijke P, Itoh S

J. Biol. Chem. 292 (10) 4099-4112 [2017-03-10; online 2017-01-23]

Affiliated researcher

Year 2016

PubMed DOI Crossref

NDST2 (N-Deacetylase/N-Sulfotransferase-2) Enzyme Regulates Heparan Sulfate Chain Length.

Deligny A, Dierker T, Dagälv A, ..., Merry CLR, Kjellén L

J. Biol. Chem. 291 (36) 18600-18607 [2016-09-02; online 2016-07-07]

Affiliated researcher

PubMed DOI Crossref

Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation.

Watanabe Y, Papoutsoglou P, Maturi V, ..., Heldin CH, Moustakas A

J. Biol. Chem. 291 (24) 12706-12723 [2016-06-10; online 2016-04-21]

Affiliated researcher

PubMed DOI Crossref

The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling.

Rorsman C, Tsioumpekou M, Heldin CH, Lennartsson J

J. Biol. Chem. 291 (22) 11608-11618 [2016-05-27; online 2016-04-05]

Affiliated researcher

PubMed DOI Crossref

AP-1 Is a Key Regulator of Proinflammatory Cytokine TNFα-mediated Triple-negative Breast Cancer Progression.

Qiao Y, He H, Jonsson P, ..., Zhao C, Dahlman-Wright K

J. Biol. Chem. 291 (10) 5068-5079 [2016-03-04; online 2016-01-20]

Affiliated researcher

Year 2015

PubMed DOI Crossref

Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor.

Griese JJ, Kositzki R, Schrapers P, ..., Haumann M, Högbom M

J. Biol. Chem. 290 (42) 25254-25272 [2015-10-16; online 2015-08-31]

Affiliated researcher

PubMed DOI Crossref

Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response.

O'Callaghan P, Li JP, Lannfelt L, Lindahl U, Zhang X

J. Biol. Chem. 290 (24) 14904-14914 [2015-06-12; online 2015-04-13]

Affiliated researcher

PubMed DOI Crossref

Exploration of the arrest peptide sequence space reveals arrest-enhanced variants.

Cymer F, Hedman R, Ismail N, von Heijne G

J. Biol. Chem. 290 (16) 10208-10215 [2015-04-17; online 2015-02-24]

Affiliated researcher

PubMed DOI Crossref

Rewired metabolism in drug-resistant leukemia cells: a metabolic switch hallmarked by reduced dependence on exogenous glutamine.

Stäubert C, Bhuiyan H, Lindahl A, ..., Lehtiö J, Nordström A

J. Biol. Chem. 290 (13) 8348-8359 [2015-03-27; online 2015-02-19]

Affiliated researcher

PubMed DOI Crossref

Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.

Jendresen CB, Cui H, Zhang X, ..., Nilsson LN, Li JP

J. Biol. Chem. 290 (8) 5053-5064 [2015-02-20; online 2014-12-29]

Affiliated researcher

Year 2014

PubMed DOI Crossref

The Eph tyrosine kinase receptors EphB2 and EphA2 are novel proteolytic substrates of tissue factor/coagulation factor VIIa.

Eriksson O, Ramström M, Hörnaeus K, ..., Mokhtari D, Siegbahn A

J. Biol. Chem. 289 (47) 32379-32391 [2014-11-21; online 2014-10-03]

Affiliated researcher

PubMed DOI Crossref

Platelet-derived growth factor β-receptor, transforming growth factor β type I receptor, and CD44 protein modulate each other's signaling and stability.

Porsch H, Mehić M, Olofsson B, Heldin P, Heldin CH

J. Biol. Chem. 289 (28) 19747-19757 [2014-07-11; online 2014-05-23]

Affiliated researcher

PubMed DOI Crossref

Increased C-telopeptide cross-linking of tendon type I collagen in fibromodulin-deficient mice.

Kalamajski S, Liu C, Tillgren V, ..., Weis M, Eyre DR

J. Biol. Chem. 289 (27) 18873-18879 [2014-07-04; online 2014-05-21]

Affiliated researcher

Year 2013

PubMed DOI Crossref

Activated Cdc42-associated kinase 1 (Ack1) is required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor recruitment to lipid rafts and induction of cell death.

Linderoth E, Pilia G, Mahajan NP, Ferby I

J. Biol. Chem. 288 (46) 32922-32931 [2013-11-15; online 2013-10-01]

Affiliated researcher

PubMed DOI Crossref

Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase of Trypanosoma brucei.

Lu J, Vodnala SK, Gustavsson AL, ..., Rottenberg ME, Holmgren A

J. Biol. Chem. 288 (38) 27456-27468 [2013-09-20; online 2013-07-29]

Affiliated researcher

PubMed DOI Crossref

MicroRNA-24 suppression of N-deacetylase/N-sulfotransferase-1 (NDST1) reduces endothelial cell responsiveness to vascular endothelial growth factor A (VEGFA).

Kasza Z, Fredlund Fuchs P, Tamm C, ..., Kjellén L, Kreuger J

J. Biol. Chem. 288 (36) 25956-25963 [2013-09-06; online 2013-07-24]

Affiliated researcher

PubMed DOI Crossref

Structure-based Discovery of Antagonists of Nuclear Receptor LRH-1

Benod C, Carlsson J, Uthayaruban R, ..., Sablin EP, Fletterick RJ

J. Biol. Chem. 288 (27) 19830-19844 [2013-07-05; online 2013-05-10]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

The Fer tyrosine kinase is important for platelet-derived growth factor-BB-induced signal transducer and activator of transcription 3 (STAT3) protein phosphorylation, colony formation in soft agar, and tumor growth in vivo.

Lennartsson J, Ma H, Wardega P, ..., Hellberg C, Heldin CH

J. Biol. Chem. 288 (22) 15736-15744 [2013-05-31; online 2013-04-15]

Affiliated researcher

PubMed DOI Crossref

Dislocation by the m-AAA protease increases the threshold hydrophobicity for retention of transmembrane helices in the inner membrane of yeast mitochondria.

Botelho SC, Tatsuta T, von Heijne G, Kim H

J. Biol. Chem. 288 (7) 4792-4798 [2013-02-15; online 2013-01-02]

Affiliated researcher

PubMed DOI Crossref

A specific and essential role for Na,K-ATPase α3 in neurons co-expressing α1 and α3.

Azarias G, Kruusmägi M, Connor S, ..., Broberger C, Aperia A

J. Biol. Chem. 288 (4) 2734-2743 [2013-01-25; online 2012-11-29]

Affiliated researcher

Year 2012

PubMed DOI Crossref

Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation.

Neumayer G, Helfricht A, Shim SY, ..., Helleday T, Nguyen MD

J. Biol. Chem. 287 (50) 42206-42222 [2012-12-07; online 2012-10-08]

Affiliated researcher

PubMed DOI Crossref

Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease.

Jeppsson F, Eketjäll S, Janson J, ..., Bueters T, Fälting J

J. Biol. Chem. 287 (49) 41245-41257 [2012-11-30; online 2012-10-09]

Affiliated researcher

PubMed DOI Crossref

Dual Effect of Phosphatidyl (4,5)-Bisphosphate PIP2on Shaker K+Channels

Abderemane-Ali F, Es-Salah-Lamoureux Z, Delemotte L, ..., Baró I, Loussouarn G

J. Biol. Chem. 287 (43) 36158-36167 [2012-10-19; online 2012-08-29]

Lucie Delemotte SciLifeLab Fellow

PubMed DOI Crossref

On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis.

Holmborn K, Habicher J, Kasza Z, ..., Kreuger J, Ledin J

J. Biol. Chem. 287 (40) 33905-33916 [2012-09-28; online 2012-08-06]

Affiliated researcher

PubMed DOI Crossref

Antiparallel dimers of the small multidrug resistance protein EmrE are more stable than parallel dimers.

Lloris-Garcerá P, Bianchi F, Slusky JS, ..., Daley DO, von Heijne G

J. Biol. Chem. 287 (31) 26052-26059 [2012-07-27; online 2012-06-14]

Affiliated researcher

PubMed DOI Crossref

Use of structural phylogenetic networks for classification of the ferritin-like superfamily.

Lundin D, Poole AM, Sjöberg BM, Högbom M

J. Biol. Chem. 287 (24) 20565-20575 [2012-06-08; online 2012-04-25]

Affiliated researcher

PubMed DOI Crossref

Efficient glycosylphosphatidylinositol (GPI) modification of membrane proteins requires a C-terminal anchoring signal of marginal hydrophobicity.

Galian C, Björkholm P, Bulleid N, von Heijne G

J. Biol. Chem. 287 (20) 16399-16409 [2012-05-11; online 2012-03-19]

Affiliated researcher

PubMed DOI Crossref

Transcriptional induction of salt-inducible kinase 1 by transforming growth factor β leads to negative regulation of type I receptor signaling in cooperation with the Smurf2 ubiquitin ligase.

Lönn P, Vanlandewijck M, Raja E, ..., Heldin CH, Moustakas A

J. Biol. Chem. 287 (16) 12867-12878 [2012-04-13; online 2012-02-29]

Affiliated researcher

PubMed DOI Crossref

Undersulfation of heparan sulfate restricts differentiation potential of mouse embryonic stem cells.

Forsberg M, Holmborn K, Kundu S, ..., Kjellén L, Forsberg-Nilsson K

J. Biol. Chem. 287 (14) 10853-10862 [2012-03-30; online 2012-02-01]

Affiliated researcher

PubMed DOI Crossref

Regulation of transcription factor Twist expression by the DNA architectural protein high mobility group A2 during epithelial-to-mesenchymal transition.

Tan EJ, Thuault S, Caja L, ..., Heldin CH, Moustakas A

J. Biol. Chem. 287 (10) 7134-7145 [2012-03-02; online 2012-01-11]

Affiliated researcher

Year 2011

PubMed DOI Crossref

Flanking residues help determine whether a hydrophobic segment adopts a monotopic or bitopic topology in the endoplasmic reticulum membrane.

Nørholm MH, Shulga YV, Aoki S, Epand RM, von Heijne G

J. Biol. Chem. 286 (28) 25284-25290 [2011-07-15; online 2011-05-23]

Affiliated researcher

PubMed DOI Crossref

Exocyst complex component 3-like 2 (EXOC3L2) associates with the exocyst complex and mediates directional migration of endothelial cells.

Barkefors I, Fuchs PF, Heldin J, ..., Forsberg-Nilsson K, Kreuger J

J. Biol. Chem. 286 (27) 24189-24199 [2011-07-08; online 2011-05-12]

Affiliated researcher

PubMed DOI Crossref

TGFbeta activates mitogen- and stress-activated protein kinase-1 (MSK1) to attenuate cell death.

van der Heide LP, van Dinther M, Moustakas A, ten Dijke P

J. Biol. Chem. 286 (7) 5003-5011 [2011-02-18; online 2010-11-24]

Affiliated researcher

Year 2010

PubMed DOI Crossref

Structure Determination and Improved Model of Plant Photosystem I

Amunts A, Toporik H, Borovikova A, Nelson N

J. Biol. Chem. 285 (5) 3478-3486 [2010-01-29; online 2009-11-18]

Alexey Amunts SciLifeLab Fellow

Year 2008

PubMed DOI Crossref

Human Wrnip1 is localized in replication factories in a ubiquitin-binding zinc finger-dependent manner.

Crosetto N, Bienko M, Hibbert RG, ..., Sixma TK, Dikic I

J. Biol. Chem. 283 (50) 35173-35185 [2008-12-12; online 2008-10-07]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significance.

Guo C, Tang TS, Bienko M, Dikic I, Friedberg EC

J. Biol. Chem. 283 (8) 4658-4664 [2008-02-22; online 2007-12-26]

Magda Bienko SciLifeLab Fellow

Year 2007

PubMed DOI Crossref

Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis.

Henriksson LM, Unge T, Carlsson J, ..., Mowbray SL, Jones TA

J. Biol. Chem. 282 (27) 19905-19916 [2007-07-06; online 2007-05-09]

Jens Carlsson SciLifeLab Fellow