Jacobson KA

Family name	Jacobson
Given name	Kenneth A
Initials	KA
ORCID	ORCID 0000-0001-8104-1493
Affiliations	Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health Bethesda Maryland 20892 USA.

4 publications

PubMed DOI Crossref

Adenosine A2A receptor antagonists: from caffeine to selective non-xanthines.

Jacobson KA, Gao ZG, Matricon P, Eddy MT, Carlsson J

Br J Pharmacol 179 (14) 3496-3511 [2022-07-00; online 2020-06-19]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Fragment-based design of selective GPCR ligands guided by free energy simulations.

Matricon P, Vo DD, Gao ZG, ..., Jacobson KA, Carlsson J

Chem. Commun. (Camb.) 57 (92) 12305-12308 [2021-11-19; online 2021-11-19]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Ligand design by targeting a binding site water

Matricon P, Suresh RR, Gao ZG, ..., Jacobson KA, Carlsson J

Chem Sci 12 (3) 960-968 [2021-00-00; online 2021-00-00]

Jens Carlsson SciLifeLab Fellow

PubMed DOI Crossref

Fragment optimization for GPCRs by molecular dynamics free energy calculations: Probing druggable subpockets of the A 2A adenosine receptor binding site.

Matricon P, Ranganathan A, Warnick E, ..., Jacobson KA, Carlsson J

Sci Rep 7 (1) 6398 [2017-07-25; online 2017-07-25]

Affiliated researcher Jens Carlsson SciLifeLab Fellow

SciLifeLab Data Centre

Publications 9.5.1