Cell Chem Biol

A machine learning and live-cell imaging tool kit uncovers small molecules induced phospholipidosis.

Hu H, Tjaden A, Knapp S, Antolin AA, Müller S

Cell Chem Biol 30 (12) 1634-1651.e6 [2023-12-21; online 2023-10-04]

NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir.

Zhang SM, Rehling D, Jemth AS, ..., Stenmark P, Helleday T

Cell Chem Biol 28 (12) 1693-1702.e6 [2021-12-16; online 2021-06-29]

Aggregated Aβ1-42 Is Selectively Toxic for Neurons, Whereas Glial Cells Produce Mature Fibrils with Low Toxicity in Drosophila.

Jonson M, Nyström S, Sandberg A, ..., Thor S, Hammarström P

Cell Chem Biol 25 (5) 595-610.e5 [2018-05-17; online 2018-04-12]

SciLifeLab Fellow Wojciech Michno

Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery.

Simm J, Klambauer G, Arany A, ..., Moreau Y, Ceulemans H

Cell Chem Biol 25 (5) 611-618.e3 [2018-05-17; online 2018-03-01]

Affiliated researcher

Lipids Shape the Electron Acceptor-Binding Site of the Peripheral Membrane Protein Dihydroorotate Dehydrogenase.

Costeira-Paulo J, Gault J, Popova G, ..., Marklund EG, Landreh M

Cell Chem Biol 25 (3) 309-317.e4 [2018-03-15; online 2018-01-18]

Affiliated researcher

The Next Step Forward in Ubiquitin-Specific Protease 7 Selective Inhibition.

Desroses M, Altun M

Cell Chem Biol 24 (12) 1429-1431 [2017-12-21; online 2017-12-23]

Affiliated researcher