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bioRxiv - (-) - |
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High Resolution Crystal Structure of the Pyruvate Kinase Tetramer in Complex with the Allosteric Activator Mitapivat/AG-348
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MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations.
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bioRxiv - (-) - |
2024-05-03 |
2024-05-03 |
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Differential expression of plasma proteins in pregnant women exposed to Plasmodium falciparum malaria
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Kanoi BN, Waweru H, Kobia FM, ..., Gitaka J, Kamali-Moghaddam M |
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Determinants of the Divergent Salmonella and Shigella Epithelial Colonization Strategies Resolved in Human Enteroids and Colonoids
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Spatial transcriptomics Visium data for mouse bleomycin model of lung fibrosis
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Bioinformatics 40 (5) - |
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Abstract PO3-25-07: Characterization of tertiary lymphoid structures and its association with response to immune checkpoint inhibitors in triple negative breast cancer using spatial transcriptomics
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Cancer Res. 84 (9_Supplement) PO3-25-07-PO3-25-07 |
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Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in Relapsed Myeloblasts.
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Nat Commun 15 (1) 3581 |
2024-04-27 |
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bioRxiv - (-) - |
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New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project.
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Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse
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Elife 13 (-) - |
2024-04-26 |
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Sci Rep 14 (1) 9458 |
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Nat Commun 15 (1) 3470 |
2024-04-24 |
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Two Novel [68Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar11]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer.
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Mol. Cell 84 (8) 1527-1540.e7 |
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Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood
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bioRxiv - (-) - |
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bioRxiv - (-) - |
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2024-04-10 |
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2024-04-10 |
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NPJ Syst Biol Appl 10 (1) 37 |
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The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds.
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2024-04-05 |
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Int J Mol Sci 25 (7) - |
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Angewandte Chemie 136 (14) - |
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2024-04-01 |
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2024-04-01 |
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Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents.
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Genetic Investigation of Consanguineous Pakistani Families Segregating Rare Spinocerebellar Disorders.
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2023-07-06 |
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Reconstructing the transport cycle in the sugar porter superfamily using coevolution-powered machine learning.
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Evaluation of AlphaFold-Multimer prediction on multi-chain protein complexes.
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Bioinformatics 39 (7) - |
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Mucosal immune responses following a fourth SARS-CoV-2 vaccine dose.
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Gentle and fast all-atom model refinement to cryo-EM densities via a maximum likelihood approach.
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Evaluating the utility of brightfield image data for mechanism of action prediction.
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Genome Res 33 (7) 1162-1174 |
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Efficient mapping of accurate long reads in minimizer space with mapquik.
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A structural and resting-state functional connectivity investigation of the pulvinar in elderly individuals and Alzheimer's disease patients.
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Alzheimers Dement 19 (7) 2774-2789 |
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A multidrug-resistant Salmonella enterica Typhimurium DT104 complex lineage circulating among humans and cattle in the USA lost the ability to produce pertussis-like toxin ArtAB.
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Bioinformatics 39 (39 Suppl 1) i222-i231 |
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The draft genome of the microscopic Nemertoderma westbladi sheds light on the evolution of Acoelomorpha genomes
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Novel conformational filter allows unambiguous identification of specific conformational ensembles for the large NS3pro/NS2B Dengue-associated protease; Implications for the appropriate choice of protein conformations in drug discovery
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Contextualising samples: Supporting reference genomes of European biodiversity through sample and associated metadata collection
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The bacterial lectin LecA from P. aeruginosa alters membrane organization by dispersing ordered domains
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Commun Phys 6 (1) - |
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The AEGEAN-169 clade of bacterioplankton is synonymous with SAR11 subclade V (HIMB59) and metabolically distinct.
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mSystems 8 (3) e0017923 |
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Modulation of Pore Opening of Eukaryotic Sodium Channels by π-Helices in S6.
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J Phys Chem Lett 14 (25) 5876-5881 |
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bioRxiv - (-) - |
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Inhibition of MYC translation through targeting of the newly identified PHB-eIF4F complex as a therapeutic strategy in CLL.
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Development of new approach methods for the identification and characterization of endocrine metabolic disruptors-a PARC project.
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Front Toxicol 5 (-) 1212509 |
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Building Asymmetric Lipid Bilayers for Molecular Dynamics Simulations: What Methods Exist and How to Choose One?
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Membranes (Basel) 13 (7) - |
2023-06-29 |
2023-06-29 |
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The ACE2 receptor accelerates but is not biochemically required for SARS-CoV-2 membrane fusion.
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Chem Sci 14 (25) 6997-7004 |
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In vitro models to study natural killer cell dynamics in the tumor microenvironment.
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Front Immunol 14 (-) 1135148 |
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Synthesis and biological evaluation of novel β-lactam-metallo β-lactamase inhibitors.
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Persistent immunosuppressive effects of dibutyl phthalate exposure in adult male mice.
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Demographic Reconstruction of the Western Sheep Expansion from Whole-Genome sequences
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Structure and dynamics of differential ligand binding in the human ρ-type GABA A receptor
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Rigorous software pipeline for clinical somatic mutation analyses of solid tumors
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Host Phylogeny Structures the Gut Bacterial Community Within Galerucella Leaf Beetles.
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Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and regeneration.
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bioRxiv - (-) - |
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Reference-based cell type matching of in situ image-based spatial transcriptomics data on primary visual cortex of mouse brain.
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Sci Rep 13 (1) 9567 |
2023-06-13 |
2023-06-13 |
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A large-scale sORF screen identifies putative microproteins and provides insights into their interaction partners, localisation and function
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Population-based cohort study of oral contraceptive use and risk of depression.
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Epidemiol Psychiatr Sci 32 (-) e39 |
2023-06-12 |
2023-06-12 |
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Orthogonal proteomics methods warrant the development of Duchenne muscular dystrophy biomarkers.
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Clin Proteomics 20 (1) 23 |
2023-06-12 |
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High-throughput measurement of the content and properties of nano-sized bioparticles with single-particle profiler.
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Adiposity and sex-specific cancer risk.
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Autoencoder Model for Translating Omics Signatures
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Cerebrospinal fluid reference proteins increase accuracy and interpretability of biomarkers for brain diseases
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More than mcr: canonical plasmid- and transposon-encoded mobilized colistin resistance genes represent a subset of phosphoethanolamine transferases.
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Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo.
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The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics.
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bioRxiv - (-) - |
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Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.
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Generation of Amber Suppression Cell Lines Using CRISPR-Cas9.
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Engineered display of ganglioside-sugars on protein elicits a clonally and structurally constrained B cell response
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Contrasting outcomes of genome reduction in mikrocytids and microsporidians.
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Temporal transcriptome analysis of the endothelial response to tumour necrosis factor
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RegiSTORM: channel registration for multi-color stochastic optical reconstruction microscopy.
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BMC Bioinformatics 24 (1) 237 |
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Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA interference
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Evaluation of plasma Short chain fatty acid levels as markers for Inflammatory bowel disease.
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Ribosome clustering and surface layer reorganization in the microsporidian host-invasion apparatus
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Wnt signaling regulates MFSD2A-dependent drug delivery through endothelial transcytosis in glioma.
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2023-06-02 |
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Whole-genome informed circulating tumor DNA analysis by multiplex digital PCR for disease monitoring in B-cell lymphomas: a proof-of-concept study.
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Front Oncol 13 (-) 1176698 |
2023-06-02 |
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Merging bioactivity predictions from cell morphology and chemical fingerprint models using similarity to training data.
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J Cheminform 15 (1) 56 |
2023-06-02 |
2023-06-02 |
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Defining Vaginal Community Dynamics: daily microbiome transitions, the role of menstruation, bacteriophages and bacterial genes
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Abstract A051: The spatial landscape of clonal somatic copy number alterations in benign and malignant prostate epithelia
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Prenatal and Early Childhood Infections and Subsequent Risk of Obsessive-Compulsive Disorder and Tic Disorders: A Nationwide, Sibling-Controlled Study.
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Isolated Hepatic Perfusion With Melphalan for Patients With Isolated Uveal Melanoma Liver Metastases: A Multicenter, Randomized, Open-Label, Phase III Trial (the SCANDIUM Trial).
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First-in-human (FIH) phase I dose escalation study (part A) of the first oral allosteric modulator of phosphoinositide 3-kinase inhibitor delta (PI3Kδ) roginolisib in patients with advanced cancer and dose confirmation in uveal melanoma (part B).
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Barcoded Consortium Infections: A Scalable, Internally Controlled Method to Study Host Cell Binding and Invasion by Pathogenic Bacteria.
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Analysis of Breast Cancer Family History, Estrogen Receptor Status, and Breast Cancer Outcomes in Sweden.
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A survey of mapping algorithms in the long-reads era.
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Two‐view attention‐guided convolutional neural network for mammographic image classification
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The role of eIF4F-driven mRNA translation in regulating the tumour microenvironment.
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The Long Noncoding RNA LINC00958 Is Induced in Psoriasis Epidermis and Modulates Epidermal Proliferation.
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Relation of different CSF biosignatures to clinical phenotypes in a memory clinic cohort
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Alzheimers Dement 19 (S2) - |
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Protein Profiling in Presymptomatic Individuals Separates Myeloperoxidase-Antineutrophil Cytoplasmic Antibody and Proteinase 3-Antineutrophil Cytoplasmic Antibody Vasculitides.
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POS1468 A HIGH GENETIC RISK OF SLE IS ASSOCIATED WITH AN INCREASED RISK OF MYOCARDIAL INFARCTION AND IMPAIRED KIDNEY FUNCTION; A COMBINED OBSERVATIONAL AND MENDELIAN RANDOMIZATION STUDY
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POS1438 ANALYSIS OF THE PLASMA PROTEOME PROVIDES MECHANISTIC INSIGHTS INTO THE PATHOPHYSIOLOGY OF ANCA-ASSOCIATED VASCULITIS
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POS0538 THE IMPACT OF IMMUNOMODULATING TREATMENT ON THE SEROLOGICAL IMMUNOGENICITY FOLLOWING THREE DOSES OF COVID-19 VACCINE AND PERSISTENCE OF IMMUNOGENICITY OF TWO VACCINE DOSES IN PATIENTS WITH INFLAMMATORY RHEUMATIC DISEASES - A SWEDISH STUDY (COVID19-REUMA)
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The Drug Efficacy Testing in Ex Vivo 3D Cultures (DETECt) platform enables rapid identification of effective drugs and drug combinations for ovarian cancer patients
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Biophys. J. 95 (12) 5851-5861 |
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Opt Express 16 (25) 21093-21104 |
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Journal of Magnetism and Magnetic Materials 320 (23) 3272-3275 |
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Mol. Cell 32 (4) 519-528 |
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In situ coating of flame-made TiO2 particles with nanothin SiO2 films.
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Langmuir 24 (21) 12553-12558 |
2008-11-04 |
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Proc. Natl. Acad. Sci. U.S.A. 105 (41) 15672-15677 |
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A new FRAP/FRAPa method for three-dimensional diffusion measurements based on multiphoton excitation microscopy.
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Biophys. J. 95 (7) 3457-3469 |
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Eur Biophys J 37 (7) 1219-1227 |
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Springer [book chapter] (-) 47-69 |
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Proc. Natl. Acad. Sci. U.S.A. 105 (32) 11224-11229 |
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Chem Mater 20 (15) 4794-4796 |
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A computerized infusion pump for control of tissue tracer concentration during positron emission tomography in vivo pharmacokinetic/pharmacodynamic measurements.
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BMC medical physics 8 (-) 2 |
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J. Med. Chem. 51 (9) 2657-2667 |
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J. Phys. Chem. B 112 (18) 5547-5550 |
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Combining docking, molecular dynamics and the linear interaction energy method to predict binding modes and affinities for non-nucleoside inhibitors to HIV-1 reverse transcriptase.
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J. Med. Chem. 51 (9) 2648-2656 |
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J Label Compd Radiopharm 51 (6) 277-282 |
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HCA 91 (5) 805-818 |
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J Microsc 230 (Pt 1) 48-60 |
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Nuclear medicine and biology 35 (3) 299-303 |
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Powder Technology 181 (3) 292-300 |
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J. Mater. Chem. 18 (30) 3547 |
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The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 is a membrane-binding protein that lacks the proposed microtubule-regulatory activity.
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BMC Microbiol. 7 (-) 70 |
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Phys Chem Chem Phys 8 (46) 5385-5395 |
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Sensors and Actuators B: Chemical 119 (2) 683-690 |
2006-12-00 |
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Molecular Biology and Evolution 23 (10) 1922-1930 |
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Preparation and evaluation of (68)Ga-DOTA-hEGF for visualization of EGFR expression in malignant tumors.
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Isolation of novel single-chain Cro proteins targeted for binding to the bcl-2 transcription initiation site by repertoire selection and subunit combinatorics.
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Biophysical Journal 89 (2) 1346-1352 |
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Nat Genet 36 (10) 1061-1063 |
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