Stressful Beginnings with Long-Term Consequences.

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Consiglio CR, Brodin P

Cell 180 (5) 820-821 [2020-03-05; online 2020-03-07]

Early-life stress can have long-term health consequences, but the mechanisms of this are unknown. In this issue of Cell, Hong et al. demonstrate one such mechanism linking perinatal corticosteroid exposure to reduced CD8+ T cell function later in life and impaired anti-cancer and anti-bacterial immune responses.

Camila Consiglio

DDLS Fellow

PubMed 32142672

DOI 10.1016/j.cell.2020.02.021

Crossref 10.1016/j.cell.2020.02.021

pii: S0092-8674(20)30165-3