The Next Step Forward in Ubiquitin-Specific Protease 7 Selective Inhibition.

Desroses M, Altun M

Cell Chem Biol 24 (12) 1429-1431 [2017-12-21; online 2017-12-23]

Ubiquitin-specific protease 7 is a validated anticancer target; thus, selective USP7 inhibitors are of great interest. In this issue of Cell Chemical Biology, Lamberto et al. (2017) and Pozhidaeva et al. (2017) report important insights into the structural inhibitor-enzyme interplay, lighting the way toward the development of selective inhibitors.

Affiliated researcher

PubMed 29272698

DOI 10.1016/j.chembiol.2017.12.003

Crossref 10.1016/j.chembiol.2017.12.003

pii: S2451-9456(17)30430-0


Publications 7.1.2