Artursson P

Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparib.

Zhang X, Rameika N, Zhong L, ..., Globisch D, Sjöblom T

EBioMedicine 109 (-) 105368 [2024-11-00; online 2024-10-04]

Daniel Globisch SciLifeLab Fellow

Illuminating the function of the orphan transporter, SLC22A10, in humans and other primates.

Yee SW, Ferrández-Peral L, Alentorn-Moron P, ..., Marquès-Bonet T, Giacomini KM

Nat Commun 15 (1) 4380 [2024-05-23; online 2024-05-23]

Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity.

Kvitne KE, Åsberg A, Johnson LK, ..., Hjelmesaeth J, Robertsen I

Clin Transl Sci 15 (11) 2685-2696 [2022-11-00; online 2022-09-08]

Monitoring Drug-Target Interactions through Target Engagement-Mediated Amplification on Arrays and in situ

Al-Amin R, Johansson L, Abdurakhmanov E, ..., Lundbäck T, Landegren U

- - (-) - [2021-12-06; online 2021-12-06]

Hepatocyte size fractionation allows dissection of human liver zonation.

Ölander M, Wegler C, Flörkemeier I, ..., Urdzik J, Artursson P

J. Cell. Physiol. 236 (8) 5885-5894 [2021-08-00; online 2021-01-16]

Getting a grip with kirigami.

Teleki A, Artursson P

Nat Mater 20 (8) 1043-1044 [2021-08-00; online 2021-07-30]

Alexandra Teleki SciLifeLab Fellow

Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes.

Wegler C, Matsson P, Krogstad V, ..., Andersson TB, Artursson P

Mol. Pharm. 18 (4) 1792-1805 [2021-04-05; online 2021-03-19]

Cell-type-resolved proteomic analysis of the human liver.

Ölander M, Wiśniewski JR, Artursson P

Liver Int. 40 (7) 1770-1780 [2020-07-00; online 2020-04-12]

A new opening for orally taken peptide drugs.

Artursson P, Lundquist P

Nat Biomed Eng 4 (1) 12-13 [2020-01-00; online 2020-01-16]