Mikael Sellin

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SciLifeLab Fellow since 2016.

Primary: Shown in the list of current labels.

Year 2025

PubMed DOI Crossref
NAIP/NLRC4 inflammasome dynamics in murine enteroids are tuned by NAIP ligand concentration and epithelial cell differentiation.
Andreassen PR, Ernst C, Pimentel Mendes M, ..., Hardt WD, Vorholt JA
Cell Reports 44 (8) 116143 [2025-08-26; online 2025-08-20]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Matrix-M adjuvant triggers inflammasome activation and enables antigen cross-presentation through induction of lysosomal membrane permeabilization.
Zarnegar B, Carow B, Eriksson J, ..., Stertman L, Lunderius Andersson C
NPJ Vaccines 10 (1) 184 [2025-08-05; online 2025-08-05]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Mast Cell Phenotypic Heterogeneity Impacts the Interplay with Pathogenic Salmonella Typhimurium Bacteria.
von Beek C, Prensa GI, Andersson JHM, Pejler G, Sellin ME
Eur. J. Immunol. 55 (8) e70040 [2025-08-00; online 2025-08-21]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Determinants of divergent Salmonella and Shigella epithelial colonization strategies resolved in human enteroids and colonoids.
Geiser P, Di Martino ML, Lopes ACC, ..., Eriksson J, Sellin ME
MBio 16 (7) e0091125 [2025-07-09; online 2025-05-30]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems.
Tjakra M, Chakrapeesirisuk N, Jacobson M, ..., Teleki A, Bergström CAS
Mol. Pharm. 22 (7) 4032-4045 [2025-07-07; online 2025-06-10]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen.
Di Martino ML, Jenniches L, Bhetwal A, ..., Barquist L, Sellin ME
Nat. Genet. 57 (7) 1730-1741 [2025-07-00; online 2025-06-12]
Mikael Sellin SciLifeLab Fellow

Year 2024

PubMed DOI Crossref
OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids.
Mickols E, Meyer A, Handin N, ..., Karlgren M, Artursson P
Sci Rep 14 (1) 17334 [2024-07-27; online 2024-07-27]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution.
Ernst C, Andreassen PR, Giger GH, ..., Hardt WD, Vorholt JA
PLoS Biol. 22 (4) e3002597 [2024-04-00; online 2024-04-29]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Salmonella T3SS-2 virulence enhances gut-luminal colonization by enabling chemotaxis-dependent exploitation of intestinal inflammation.
Gül E, Huuskonen J, Abi Younes A, ..., Bakkeren E, Hardt WD
Cell Reports 43 (3) 113925 [2024-03-26; online 2024-03-07]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis.
Bergman S, Andresen L, Kjellin J, ..., Sellin ME, Holmqvist E
mSphere 9 (3) e0001824 [2024-03-26; online 2024-02-27]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Equine enteroid-derived monolayers recapitulate key features of parasitic intestinal nematode infection.
Hellman S, Martin F, Tydén E, ..., Svedberg P, Fossum C
Vet Res 55 (1) 25 [2024-02-27; online 2024-02-27]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection.
von Beek C, Fahlgren A, Geiser P, ..., Pejler G, Sellin ME
Nat Commun 15 (1) 904 [2024-01-30; online 2024-01-30]
Mikael Sellin SciLifeLab Fellow

Year 2023

PubMed DOI Crossref
Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice.
Fattinger SA, Maurer L, Geiser P, ..., Sellin ME, Hardt WD
Proc. Natl. Acad. Sci. U.S.A. 120 (48) e2315503120 [2023-11-28; online 2023-11-21]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Epithelial inflammasomes, gasdermins, and mucosal inflammation - Lessons from Salmonella and Shigella infected mice.
Gül E, Fattinger SA, Sellin ME, Hardt WD
Semin Immunol 70 (-) 101812 [2023-08-08; online 2023-08-08]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Barcoded Consortium Infections: A Scalable, Internally Controlled Method to Study Host Cell Binding and Invasion by Pathogenic Bacteria.
Di Martino ML, Sellin ME
Methods in molecular biology (Clifton, N.J.) 2674 (-) 295-311 [2023-06-01; online 2023-06-01]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells during Salmonella gut infection.
Gül E, Enz U, Maurer L, ..., Sellin ME, Hardt WD
PLoS Pathog 19 (6) e1011235 [2023-06-00; online 2023-06-29]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Chemoselective bicyclobutane-based mass spectrometric detection of biological thiols uncovers human and bacterial metabolites.
Kaur A, Lin W, Dovhalyuk V, ..., Sellin ME, Globisch D
Chem Sci 14 (20) 5291-5301 [2023-05-24; online 2023-04-06]
Daniel Globisch Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection.
Grüttner J, van Rijn JM, Geiser P, ..., Sellin ME, Svärd SG
PLoS Pathog 19 (5) e1011372 [2023-05-00; online 2023-05-04]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Time-Lapse Imaging of Inflammasome-Dependent Cell Death and Extrusion in Enteroid-Derived Intestinal Epithelial Monolayers.
Geiser P, van Rijn JM, Sellin ME
Methods in molecular biology (Clifton, N.J.) 2641 (-) 203-221 [2023-04-19; online 2023-04-19]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Epithelial and microbial determinants of colonic drug distribution.
Hammar R, Sellin ME, Artursson P
Eur J Pharm Sci 183 (-) 106389 [2023-04-01; online 2023-01-20]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
The liver kinase B1 supports mammary epithelial morphogenesis by inhibiting critical factors that mediate epithelial-mesenchymal transition.
Tzavlaki K, Ohata Y, Morén A, ..., Heldin CH, Moustakas A
J. Cell. Physiol. 238 (4) 790-812 [2023-04-00; online 2023-02-15]
Mikael Sellin SciLifeLab Fellow

Year 2022

DOI Crossref
High-efficiency transfection of<i>Acanthamoeba castellanii</i>using a cationic polymer
Moreno AB, Ek V, Eriksson J, Sellin ME, Guy L
- - (-) - [2022-12-01; online 2022-12-01]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
The VirF21:VirF30 protein ratio is affected by temperature and impacts Shigella flexneri host cell invasion.
Skovajsová E, Colonna B, Prosseda G, Sellin ME, Di Martino ML
FEMS Microbiol. Lett. 369 (1) - [2022-06-22; online 2022-05-07]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
TGFβ selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial-mesenchymal transition.
Tsubakihara Y, Ohata Y, Okita Y, ..., Heldin CH, Moustakas A
Mol Oncol 16 (12) 2330-2354 [2022-06-00; online 2022-04-10]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
A motile doublet form of Salmonella Typhimurium diversifies target search behavior at the epithelial surface.
Ek V, Fattinger SA, Florbrant A, ..., Eriksson J, Sellin ME
Mol. Microbiol. 117 (5) 1156-1172 [2022-05-00; online 2022-04-12]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
IgE cross-linking induces activation of human and mouse mast cell progenitors.
Méndez-Enríquez E, Salomonsson M, Eriksson J, ..., Sellin ME, Hallgren J
J. Allergy Clin. Immunol. 149 (4) 1458-1463 [2022-04-00; online 2021-09-04]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium.
van Rijn JM, Eriksson J, Grüttner J, ..., Svärd SG, Sellin ME
MBio 13 (1) e0002222 [2022-02-01; online 2022-02-01]
Mikael Sellin SciLifeLab Fellow

Year 2021

PubMed DOI Crossref
Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire.
Fattinger SA, Sellin ME, Hardt WD
Curr Opin Microbiol 64 (-) 9-18 [2021-12-00; online 2021-09-06]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF.
Hausmann A, Felmy B, Kunz L, ..., Sellin ME, Hardt WD
J. Exp. Med. 218 (11) - [2021-11-01; online 2021-09-16]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells.
von Beek C, Alriksson L, Palle J, ..., Sellin ME, Pejler G
PLoS ONE 16 (9) e0256708 [2021-09-07; online 2021-09-07]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Epithelium-autonomous NAIP/NLRC4 prevents TNF-driven inflammatory destruction of the gut epithelial barrier in Salmonella-infected mice.
Fattinger SA, Geiser P, Samperio Ventayol P, ..., Hardt WD, Sellin ME
Mucosal Immunol 14 (3) 615-629 [2021-05-00; online 2021-03-17]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers.
Samperio Ventayol P, Geiser P, Di Martino ML, ..., Eriksson J, Sellin ME
Proc. Natl. Acad. Sci. U.S.A. 118 (16) - [2021-04-20; online 2021-04-14]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Epithelial inflammasomes in the defense against Salmonella gut infection.
Fattinger SA, Sellin ME, Hardt WD
Curr Opin Microbiol 59 (-) 86-94 [2021-02-00; online 2020-10-28]
Mikael Sellin SciLifeLab Fellow
DOI Crossref
Cellocity: A Python package for analysis of confluent cell layer dynamics
Eriksson J, Styrström D, Sellin M
JOSS 6 (57) 2818 [2021-01-28; online 2021-01-28]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids.
Geiser P, Di Martino ML, Samperio Ventayol P, ..., Hellström PM, Sellin ME
MBio 12 (1) - [2021-01-12; online 2021-01-12]
Mikael Sellin SciLifeLab Fellow

Year 2020

PubMed DOI Crossref
Germ-free and microbiota-associated mice yield small intestinal epithelial organoids with equivalent and robust transcriptome/proteome expression phenotypes.
Hausmann A, Russo G, Grossmann J, ..., Sellin ME, Hardt WD
Cell. Microbiol. 22 (6) e13191 [2020-06-00; online 2020-03-04]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium.
Fattinger SA, Böck D, Di Martino ML, ..., Hardt WD, Sellin ME
PLoS Pathog 16 (5) e1008503 [2020-05-00; online 2020-05-04]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression.
Hausmann A, Böck D, Geiser P, ..., Sellin ME, Hardt WD
Mucosal Immunol 13 (3) 530-544 [2020-05-00; online 2020-01-17]
Mikael Sellin SciLifeLab Fellow

Year 2019

PubMed DOI Crossref
Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism.
von Beek C, Waern I, Eriksson J, ..., Guss B, Pejler G
Cell. Microbiol. 21 (9) e13064 [2019-09-00; online 2019-07-07]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut.
Bakkeren E, Huisman JS, Fattinger SA, ..., Diard M, Hardt WD
Nature 573 (7773) 276-280 [2019-09-00; online 2019-09-04]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract.
Furter M, Sellin ME, Hansson GC, Hardt WD
Cell Reports 27 (9) 2665-2678.e3 [2019-05-28; online 2019-05-30]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Barcoded Consortium Infections Resolve Cell Type-Dependent Salmonella enterica Serovar Typhimurium Entry Mechanisms.
Di Martino ML, Ek V, Hardt WD, Eriksson J, Sellin ME
MBio 10 (3) - [2019-05-21; online 2019-05-21]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production.
Paivandy A, Eriksson J, Melo FR, Sellin ME, Pejler G
Cell death discovery 5 (1) 95 [2019-05-15; online 2019-05-15]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Mucispirillum schaedleri Antagonizes Salmonella Virulence to Protect Mice against Colitis.
Herp S, Brugiroux S, Garzetti D, ..., Berry D, Stecher B
Cell Host Microbe 25 (5) 681-694.e8 [2019-05-08; online 2019-04-18]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium.
Westermann AJ, Venturini E, Sellin ME, ..., Hardt WD, Vogel J
MBio 10 (1) - [2019-01-02; online 2019-01-02]
Mikael Sellin SciLifeLab Fellow

Year 2018

PubMed DOI Crossref
Consequences of Epithelial Inflammasome Activation by Bacterial Pathogens.
Sellin ME, Müller AA, Hardt WD
J. Mol. Biol. 430 (2) 193-206 [2018-01-19; online 2017-04-25]
Affiliated researcher Mikael Sellin SciLifeLab Fellow

Year 2017

PubMed DOI Crossref
High-avidity IgA protects the intestine by enchaining growing bacteria.
Moor K, Diard M, Sellin ME, ..., Hardt WD, Slack E
Nature 544 (7651) 498-502 [2017-04-27; online 2017-04-12]
Affiliated researcher Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Inflammation boosts bacteriophage transfer between Salmonella spp.
Diard M, Bakkeren E, Cornuault JK, ..., Slack E, Hardt WD
Science (New York, N.Y.) 355 (6330) 1211-1215 [2017-03-17; online 2017-03-16]
Affiliated researcher Mikael Sellin SciLifeLab Fellow

Year 2016

PubMed DOI Crossref
IFN-γ Hinders Recovery from Mucosal Inflammation during Antibiotic Therapy for Salmonella Gut Infection.
Dolowschiak T, Mueller AA, Pisan LJ, ..., Mueller C, Hardt WD
Cell Host Microbe 20 (2) 238-249 [2016-08-10; online 2016-07-21]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection.
Müller AA, Dolowschiak T, Sellin ME, ..., LeibundGut-Landmann S, Hardt WD
PLoS Pathog 12 (6) e1005723 [2016-06-00; online 2016-06-24]
Mikael Sellin SciLifeLab Fellow

Year 2015

PubMed DOI Crossref
Inflammasomes of the intestinal epithelium
Sellin ME, Maslowski KM, Maloy KJ, Hardt WD
Trends in Immunology 36 (8) 442-450 [2015-08-00; online 2015-08-00]
Mikael Sellin SciLifeLab Fellow

Year 2014

PubMed DOI Crossref
Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during Salmonella Typhimurium Colitis
Maier L, Diard M, Sellin ME, ..., Regoes RR, Hardt WD
PLoS Pathog 10 (12) e1004557 [2014-12-18; online 2014-12-18]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
The Salmonella Typhimurium effector protein SopE transiently localizes to the early SCV and contributes to intracellular replication
Vonaesch P, Sellin ME, Cardini S, ..., Barthel M, Hardt WD
Cell Microbiol 16 (12) 1723-1735 [2014-12-00; online 2014-08-26]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Antibiotic treatment selects for cooperative virulence of Salmonella typhimurium.
Diard M, Sellin ME, Dolowschiak T, ..., Ackermann M, Hardt WD
Curr. Biol. 24 (17) 2000-2005 [2014-09-08; online 2014-08-14]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Epithelium-Intrinsic NAIP/NLRC4 Inflammasome Drives Infected Enterocyte Expulsion to Restrict Salmonella Replication in the Intestinal Mucosa
Sellin ME, Müller AA, Felmy B, ..., Maslowski KM, Hardt WD
Cell Host & Microbe 16 (2) 237-248 [2014-08-00; online 2014-08-00]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Cell type–specific expression of SEPT3-homology subgroup members controls the subunit number of heteromeric septin complexes
Sellin ME, Stenmark S, Gullberg M
MBoC 25 (10) 1594-1607 [2014-05-15; online 2014-05-15]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
A Generic Method for Design of Oligomer-Specific Antibodies
Brännström K, Lindhagen-Persson M, Gharibyan AL, ..., Forsgren L, Olofsson A
PLoS ONE 9 (3) e90857 [2014-03-11; online 2014-03-11]
Mikael Sellin SciLifeLab Fellow

Year 2013

PubMed DOI Crossref
Quantitative insights into actin rearrangements and bacterial target site selection from Salmonella Typhimurium infection of micropatterned cells
Vonaesch P, Cardini S, Sellin ME, ..., Hardt WD, Schauer K
Cell Microbiol - (-) n/a-n/a [2013-06-00; online 2013-05-30]
Mikael Sellin SciLifeLab Fellow

Year 2012

PubMed DOI Crossref
Mammalian SEPT9 isoforms direct microtubule-dependent arrangements of septin core heteromers
Sellin ME, Stenmark S, Gullberg M
MBoC 23 (21) 4242-4255 [2012-11-00; online 2012-11-00]
Mikael Sellin SciLifeLab Fellow

Year 2011

PubMed DOI Crossref
Microtubules support a disk-like septin arrangement at the plasma membrane of mammalian cells
Sellin ME, Holmfeldt P, Stenmark S, Gullberg M
MBoC 22 (23) 4588-4601 [2011-12-00; online 2011-12-00]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Deciphering the rules governing assembly order of mammalian septin complexes
Sellin ME, Sandblad L, Stenmark S, Gullberg M
MBoC 22 (17) 3152-3164 [2011-09-00; online 2011-09-00]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
The RACK1 Signaling Scaffold Protein Selectively Interacts with Yersinia pseudotuberculosis Virulence Function
Thorslund SE, Edgren T, Pettersson J, ..., Wolf-Watz H, Fällman M
PLoS ONE 6 (2) e16784 [2011-02-10; online 2011-02-10]
Mikael Sellin SciLifeLab Fellow

Year 2010

PubMed DOI Crossref
Upregulated Op18/stathmin activity causes chromosomal instability through a mechanism that evades the spindle assembly checkpoint
Holmfeldt P, Sellin ME, Gullberg M
Experimental Cell Research 316 (12) 2017-2026 [2010-07-00; online 2010-07-00]
Mikael Sellin SciLifeLab Fellow

Year 2009

PubMed DOI Crossref
Predominant regulators of tubulin monomer-polymer partitioning and their implication for cell polarization.
Holmfeldt P, Sellin ME, Gullberg M
Cell. Mol. Life Sci. 66 (20) 3263-3276 [2009-10-00; online 2009-07-08]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 assembles into a nine-subunit oligomer with potential To inhibit Toll-like receptor signaling.
Brännström K, Sellin ME, Holmfeldt P, Brattsand M, Gullberg M
Infect. Immun. 77 (3) 1144-1154 [2009-03-00; online 2009-01-05]
Mikael Sellin SciLifeLab Fellow

Year 2008

PubMed DOI Crossref
Global regulation of the interphase microtubule system by abundantly expressed Op18/stathmin.
Sellin ME, Holmfeldt P, Stenmark S, Gullberg M
Mol. Biol. Cell 19 (7) 2897-2906 [2008-07-00; online 2008-04-23]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Op18/Stathmin counteracts the activity of overexpressed tubulin-disrupting proteins in a human leukemia cell line.
Sellin ME, Holmfeldt P, Stenmark S, Gullberg M
Experimental Cell Research 314 (6) 1367-1377 [2008-04-01; online 2008-01-05]
Mikael Sellin SciLifeLab Fellow

Year 2007

PubMed DOI Crossref
The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 is a membrane-binding protein that lacks the proposed microtubule-regulatory activity.
Holmfeldt P, Brännström K, Sellin ME, ..., Carlsson SR, Gullberg M
Molecular and biochemical parasitology 156 (2) 225-234 [2007-12-00; online 2007-08-25]
Mikael Sellin SciLifeLab Fellow
SciLifeLab Data Centre
Publications 9.5.1