Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging.

Baltekin Ö, Boucharin A, Tano E, Andersson DI, Elf J

Proc. Natl. Acad. Sci. U.S.A. 114 (34) 9170-9175 [2017-08-22; online 2017-08-08]

The emergence and spread of antibiotic-resistant bacteria are aggravated by incorrect prescription and use of antibiotics. A core problem is that there is no sufficiently fast diagnostic test to guide correct antibiotic prescription at the point of care. Here, we investigate if it is possible to develop a point-of-care susceptibility test for urinary tract infection, a disease that 100 million women suffer from annually and that exhibits widespread antibiotic resistance. We capture bacterial cells directly from samples with low bacterial counts (10

Affiliated researcher

PubMed 28790187

DOI 10.1073/pnas.1708558114

Crossref 10.1073/pnas.1708558114

pii: 1708558114
pmc: PMC5576829

Publications 9.5.0