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Baltekin Ö, Boucharin A, Tano E, Andersson DI, Elf J
Proc. Natl. Acad. Sci. U.S.A. 114 (34) 9170-9175 [2017-08-22; online 2017-08-08]
The emergence and spread of antibiotic-resistant bacteria are aggravated by incorrect prescription and use of antibiotics. A core problem is that there is no sufficiently fast diagnostic test to guide correct antibiotic prescription at the point of care. Here, we investigate if it is possible to develop a point-of-care susceptibility test for urinary tract infection, a disease that 100 million women suffer from annually and that exhibits widespread antibiotic resistance. We capture bacterial cells directly from samples with low bacterial counts (10
PubMed 28790187
DOI 10.1073/pnas.1708558114
Crossref 10.1073/pnas.1708558114
pii: 1708558114
pmc: PMC5576829