SciLifeLab Fellow

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This label is applied to publications by SciLifeLab Fellows starting the year they took up their position at SciLifeLab.

Primary: Shown in the list of current labels.

Year 2026

PubMed DOI Crossref
Grey matter structural asymmetry and premenstrual dysphoric disorder
Bücklein-Ehlers E, Dubol M, Derntl B, ..., Fallgatter A, Comasco E
Neuropsychobiology - (-) 1-22 [2026-08-06; online 2026-08-06]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Tissue and cellular spatiotemporal dynamics in colon aging.
Daly AC, Cambuli F, Äijö T, ..., Regev A, Vickovic S
Nat. Biotechnol. 44 (8) 1340-1352 [2026-08-00; online 2025-10-22]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Global metabolomics profiling of glucuronides in human plasma, fecal, and cerebrospinal fluid samples.
Tsiara I, Correia MSP, Yang F, ..., Löhr JM, Globisch D
Anal Bioanal Chem 418 (16) 5059-5070 [2026-08-00; online 2025-09-01]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Escitalopram and brain reactivity to aggressive stimuli in premenstrual dysphoric disorder.
Dubol M, Gröndal M, Schmidt F, ..., Sundstrøm I, Comasco E
Br J Psychiatry - (-) 1-9 [2026-07-28; online 2026-07-28]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Impairment of Executive Functions in Premenstrual Syndrome: State or Trait?
Gnaiger AM, Werlein P, Gruschwitz P, ..., Hidalgo-Lopez E, Pletzer B
Biol Psychiatry Glob Open Sci 6 (4) 100730 [2026-07-00; online 2026-07-00]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Chromatin-associated intronic RNAs from long genes form introsomes that shape nuclear architecture in neuronal cells.
Kang W, Yip WH, Li-Wang X, ..., Carninci P, Bienko M
bioRxiv - (-) - [2026-05-27; online 2026-05-27]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Timing Matters: Leveraging Positron Emission Tomography Imaging and Hormonal Cycles for Precision Psychiatry in Female Mental Health.
May E, Comasco E, Tiepolt S, ..., Villringer A, Sacher J
Biol. Psychiatry 99 (9) 713-727 [2026-05-01; online 2026-02-23]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Women at the heart of mental science: commentary, Pinto da Costa et al.
Pinto da Costa M, de Cates AN, Dhamala E, ..., Upthegrove R, Comasco E
Br J Psychiatry 228 (5) 484-486 [2026-05-00; online 2026-02-11]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Personality and cortical architecture in premenstrual dysphoric disorder
Bücklein-Ehlers E, Dubol M, Derntl B, ..., Sundström-Poromaa I, Comasco E
Arch Womens Ment Health 29 (2) - [2026-04-00; online 2026-03-09]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Low-dose testosterone administration and oestrogen synthase availability in the female brain: A pilot study.
Dubol M, Jonasson M, Takahashi K, ..., Sundström-Poromaa I, Comasco E
J Neuroendocrinol 38 (3) e70154 [2026-03-00; online 2026-03-03]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
The role of gene-environment interactions in endocrine-sensitive life stages for shaping mental health: focus on the RE-MEND project
Abualia K, Cediel-Ulloa A, Allsopp P, ..., Rüegg J, Antczak P
Front Psychiatry 17 (-) 1738584 [2026-02-20; online 2026-02-20]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Understanding excipient interactions unlocks untapped potential of RNA-lipid nanoparticles in dry powder formulations for local pulmonary delivery.
Martini N, Deßloch L, Sych T, ..., Merkel OM, Winkeljann B
J Control Release 390 (-) 114539 [2026-02-10; online 2025-12-12]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
High-throughput screening of estrogen receptor activity in personalized mixtures of persistent organic pollutants detected in the blood of Swedish adults.
Reis L, Strand D, Höglund A, ..., Martin JW, Karlsson O
Environ. Res. 290 (-) 123388 [2026-02-01; online 2025-11-20]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Emotion Generation and Regulation in Premenstrual Dysphoric Disorder: Dysregulation of Large-Scale Brain Networks Across the Menstrual Cycle.
Stiernman L, Dubol M, Comasco E, ..., Stiernman L, Bixo M
Biol. Psychiatry 99 (3) 227-236 [2026-02-01; online 2025-06-06]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Multiplexed single-molecule characterization at the library scale.
Panfilov M, Mao G, Guo J, ..., Sabantsev A, Deindl S
Nat Protoc 21 (2) 749-774 [2026-02-00; online 2025-06-04]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Autophagy is required for the development and functionality of lacrimal gland-like organoids.
Kocak G, Korsgen ME, Amores LF, ..., Güven S, Sarkar S
Stem Cell Reports 21 (1) 102744 [2026-01-13; online 2025-12-18]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Thermodynamic principles link in vitro transcription factor affinities to single-molecule chromatin states in cells.
Schaepe JM, Fries T, Doughty BR, ..., Marklund E, Greenleaf WJ
Cell 189 (1) 307-322.e23 [2026-01-08; online 2025-11-26]
Emil Marklund SciLifeLab Fellow
PubMed DOI Crossref
Ancient RNA expression profiles from the extinct woolly mammoth.
Mármol-Sánchez E, Fromm B, Oskolkov N, ..., Friedländer MR, Dalén L
Cell 189 (1) 52-69.e22 [2026-01-08; online 2025-11-14]
DDLS Fellow Marc Friedländer SciLifeLab Fellow Tom van der Valk
PubMed DOI Crossref
Heterocyclic scaffold-fused dimethoxy-dibenzocyclooctynes for photoactivatable click chemistry.
Larsson NA, Jo T, Bremberg U, ..., Odell LR, Fürth D
Org. Biomol. Chem. 24 (1) 120-126 [2026-01-07; online 2026-01-07]
Daniel Fürth SciLifeLab Fellow
PubMed DOI Crossref
Microbial collagenase activity is linked to oral-gut translocation in advanced chronic liver disease.
Jin S, Cenier A, Wetzel D, ..., Patel VC, Schirmer M
Nat. Microbiol 11 (1) 211-227 [2026-01-00; online 2025-12-29]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

Year 2025

DOI Crossref
The collision of two genomes threatens global food security
North HL, Montejo-Kovacevich G, Amado D, ..., Omoto C, Jiggins CD
- - (-) - [2025-12-25; online 2025-12-25]
Gabriela Montejo-Kovacevich SciLifeLab Fellow
PubMed DOI Crossref
Transcriptional architecture and Pol II regulation at promoters, enhancers, and enhancer clusters in Canis lupus familiaris.
Himanen SV, Rabenius A, Aktay S, Tekoniemi J, Vihervaara A
Cell Reports 44 (12) 116698 [2025-12-23; online 2025-12-12]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Maturation of human intestinal epithelial cell layers fortifies the apical surface against Salmonella attack.
van Rijn JM, Lopes ACC, Dienhart FSV, ..., Di Martino ML, Sellin ME
Cell Reports 44 (12) 116579 [2025-12-23; online 2025-11-21]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
A human pan-disease blood atlas of the circulating proteome.
Álvez MB, Bergström S, Kenrick J, ..., Edfors F, Uhlén M
Science (New York, N.Y.) 390 (6779) eadx2678 [2025-12-18; online 2025-12-18]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Macrophages as central mediators of sympathetic neuro-immune interplay in autoimmunity.
Muntjewerff EM, Josyula VS, Lehmair F, Christoffersson G
Front Immunol 16 (-) 1654382 [2025-12-16; online 2025-12-16]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
PDGFRß targeted positron emission tomography as a non-invasive biomarker for activated hepatic stellate cells: lasts steps before clinical translation.
Yashaswini CN, Mitran B, Papadopoulos N, ..., Friedman SL, Eriksson O
EJNMMI Radiopharm Chem 10 (1) 80 [2025-12-13; online 2025-12-13]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Widespread potential for phototrophy and convergent reduction of lifecycle complexity in the dimorphic order Caulobacterales.
Hallgren J, Dharamshi JE, Rodríguez-Gijón A, ..., Garcia SL, Jonas K
Nat Commun 16 (1) 11003 [2025-12-12; online 2025-12-12]
Kristina Jonas Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Inter- and intra-individual differences in brain sex map to neuroendocrine profiles.
Bon GM, Kimmig AS, Comasco E, Derntl B, Kaufmann T
bioRxiv - (-) - [2025-12-11; online 2025-12-11]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Ultra-large virtual screening unveils potent agonists of the neuromodulatory orphan receptor GPR139.
Cabeza de Vaca I, Trapkov B, Shen L, ..., Hauser AS, Carlsson J
Nat Commun 17 (1) 129 [2025-12-09; online 2025-12-09]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Predicting allergy and postpartum depression from an incomplete compositional microbiome.
Shternshis A, Tong B, Skalkidou A, ..., Hugerth LW, Singh P
BMC Genomics 26 (1) 1092 [2025-12-06; online 2025-12-06]
DDLS Fellow Luisa Hugerth Prashant Singh SciLifeLab Fellow
DOI Crossref
Safe-and-sustainable-by-design approach to polyesters from non-oestrogenic bisphenols
Margarita C, Pierozan P, Subramaniyan S, ..., Karlsson O, Lundberg H
Nat Sustain 9 (1) 86-95 [2025-12-04; online 2025-12-04]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Microbial model communities exhibit widespread metabolic interdependencies.
Pacheco-Valenciana A, Tausch A, Veseli I, ..., Andersson AF, Garcia SL
Commun Biol 8 (1) 1752 [2025-12-03; online 2025-12-03]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Trait- versus state- grey matter volume alterations in premenstrual dysphoric disorder.
Stiernman L, Dubol M, Sundström-Poromaa I, Bixo M, Comasco E
BMC Psychiatry 25 (1) 1139 [2025-12-02; online 2025-12-02]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Ga-68-Labeled Affibody Molecule-Based Radiopharmaceutical Targeting Platelet Derived Growth Factor Receptor Beta for Detection of Active Fibrosis in Patients with Myocardial Infarction.
Velikyan I, Grinnemo KH, Flodin V, ..., Korsgren O, Eriksson O
Pharmaceuticals (Basel, Switzerland) 18 (12) - [2025-12-01; online 2025-12-01]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
All-optical strategies to minimize photobleaching in reversibly switchable fluorescent proteins.
Marín-Aguilera G, Pennacchietti F, Volpato A, ..., Widengren J, Testa I
Nat Commun 16 (1) 10843 [2025-12-01; online 2025-12-01]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Targeting PKLR in liver diseases.
Yuan M, Shi M, Yang H, ..., Altay O, Mardinoglu A
Trends Endocrinol Metab 36 (12) 1099-1110 [2025-12-00; online 2025-04-11]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Positron emission tomography to assess drug occupancy at peripheral and central incretin receptors.
Khalil A, Velikyan I, Xiong M, ..., Wagner M, Eriksson O
EBioMedicine 122 (-) 106033 [2025-12-00; online 2025-11-21]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
From slices to deep dishes: spatial transcriptomics and translatomics of thick tissue blocks.
Pleška M, Vickovic S
Nat. Methods 22 (12) 2500-2502 [2025-12-00; online 2025-11-25]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Diversity and evolution of alphaproteobacterial dimorphism.
Hallgren J, Jonas K
Curr Opin Microbiol 88 (-) 102661 [2025-12-00; online 2025-09-09]
Kristina Jonas SciLifeLab Fellow
DOI Crossref
Tangerine: a new family of Starships from lichen-forming fungi
Tagirdzhanova G, Brown NE, Bucknell AH, ..., Gluck-Thaler E, Talbot NJ
- - (-) - [2025-11-27; online 2025-11-27]
SciLifeLab Fellow
DOI Crossref
OncoRisk: A state-of-the-art Web Server for bridging the oncogenic databases and pan-cancer cohorts to the translational oncology
Mardinoglu A, Song X, Green E, ..., Uhlén M, Zhang C
- - (-) - [2025-11-26; online 2025-11-26]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Extending the shelf life of ⁶⁸Ge/⁶⁸Ga generators via preconcentration of [⁶⁸Ga]GaCl₃ for preclinical application.
Mallapura H, Eriksson O
EJNMMI Radiopharm Chem 10 (1) 76 [2025-11-26; online 2025-11-26]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Chromogranin A and catestatin regulate pancreatic islet homeostasis, endocrine function, and neurotransmitter signaling.
Muntjewerff EM, Epremidze D, Nezhyva M, ..., Mahata SK, Christoffersson G
Commun Biol 8 (1) 1684 [2025-11-26; online 2025-11-26]
Daniel Espes Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Multi-cellular phenotypic dynamics during the progression of an immunocompetent breast cancer model.
Gsell L, Watson SS, Sutevski I, ..., Joyce JA, Hausser J
iScience 28 (11) 113808 [2025-11-21; online 2025-10-23]
Jean Hausser SciLifeLab Fellow
PubMed DOI Crossref
Depression is an independent risk factor for stroke reccurence and cognitive impairment in stroke patients.
Cankaya S, Safa SS, Karakus A, ..., Kumral E, Yulug B
Transl Psychiatry 15 (1) 492 [2025-11-21; online 2025-11-21]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Cognitive impairment in tension-type headache is associated with altered hippocampal functional connectivity.
Yulug B, Yalcınkaya A, Safa SS, ..., Hanoglu L, Mardinoglu A
iScience 28 (11) 113850 [2025-11-21; online 2025-10-23]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration.
Murray ME, Smith C, Menon V, ..., Dugger BN, Phatnani H
Neuron 113 (22) 3703-3721 [2025-11-19; online 2025-07-18]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Noscapine-bile acid hybrids as novel anticancer agents.
Babanezhad Harikandei K, Salehi P, Hasanpour Z, ..., Asghari SM, Mardinoglu A
RSC Med Chem 16 (11) 5511-5533 [2025-11-13; online 2025-08-29]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
A streamlined nanopore-compatible 5PSeq protocol for rapid phenotypic antimicrobial sensitivity testing
Liu H, Huch S, Hull R, ..., Du J, Pelechano V
- - (-) - [2025-11-12; online 2025-11-12]
SciLifeLab Fellow
PubMed DOI Crossref
Targeting the parietal memory network with tDCS in MCI: study protocol for a randomized controlled trial.
Cankaya S, Akturk A, Karakus A, ..., Mardinoglu A, Yulug B
Front. Hum. Neurosci. 19 (-) 1661790 [2025-11-10; online 2025-11-10]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
ALC1 Finds a New Foothold on the Nucleosome’s Super-Groove
Bridges HR, Bacic L, Deindl S, Gaullier G
- - (-) - [2025-11-10; online 2025-11-10]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
The mRNA architecture of the termination site primes programmed stop codon readthrough events in Drosophila
Kansara L, Wolfstetter G, Wintermayr D, ..., Friedländer MR, Engström Y
- - (-) - [2025-11-07; online 2025-11-07]
Marc Friedländer SciLifeLab Fellow
DOI Crossref
FOLD-FISH step-by-step protocol v1
Li-Wang X, Zetterberg A, Bienko M
- - (-) - [2025-11-07; online 2025-11-07]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Mettl15-Mettl17 modulates the transition from early to late pre-mitoribosome.
Zgadzay Y, Mirabello C, Wanes G, ..., Gahura O, Amunts A
Structure 33 (11) 1904-1915.e3 [2025-11-06; online 2025-08-28]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Longitudinal development of sex differences in the limbic system is associated with age, puberty and mental health.
Matte Bon G, Walther J, Comasco E, Derntl B, Kaufmann T
Commun Biol 8 (1) 1524 [2025-11-05; online 2025-11-05]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Adaptive introgression from Pacific herring to Atlantic herring in the brackish Baltic Sea
Ferreira MS, Felkel S, Fuentes-Pardo AP, ..., Pettersson M, Andersson L
- - (-) - [2025-11-03; online 2025-11-03]
Mafalda Sousa Ferreira SciLifeLab Fellow
DOI Crossref
Neuroimmune interactions in the pancreas in health and disease- Identifying the components of nerve-macrophage association 2911
Sai Josyula V, Merchant K, Reiche M, ..., Lindsay R, Christoffersson G
J. Immunol. 214 (Supplement_1) - [2025-11-01; online 2025-11-20]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
IntegrAlign: a comprehensive tool for multi-immunofluorescence panel integration through image alignment.
Hermet L, Laoubi L, Scavino M, ..., Caux C, Hubert M
Bioinformatics 41 (11) - [2025-11-01; online 2025-10-16]
Jean Hausser SciLifeLab Fellow
PubMed DOI Crossref
White Matter Regional Volumes in Relation to Menstrual Cycle Phase and Premenstrual Dysphoric Disorder.
Stenhammar E, Dubol M, Stiernman L, ..., Bixo M, Comasco E
Biol Psychiatry Glob Open Sci 5 (6) 100573 [2025-11-00; online 2025-07-28]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
The pcnB gene sustains Shigella flexneri virulence.
Frisch T, Geiser P, Komi M, ..., Sellin ME, Di Martino ML
PLoS Pathog 21 (11) e1013727 [2025-11-00; online 2025-11-20]
Mikael Sellin SciLifeLab Fellow
DOI Crossref
Skalierbares Darmorganoidmodell enthüllt humanpathogene Infektionsfaktoren
Jenniches L, Di Martino ML, Sellin ME, Barquist L
Biospektrum 31 (7) 712-714 [2025-11-00; online 2025-11-22]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Proximity extension assay inflammatory profiling cannot distinguish the presence of residual C-peptide in patients with long-standing type 1 diabetes.
Anvari E, Lundkvist P, Singh K, Espes D
Acta diabetologica 62 (11) 1987-1996 [2025-11-00; online 2025-06-05]
Daniel Espes SciLifeLab Fellow
DOI Crossref
Differences in the Fecal Metabolome of Autoimmune Pancreatitis Patients
Nikolić S, Dovhalyuk V, Yang F, ..., Löhr JM, Globisch D
Pancreatology 25 (7) 1325 [2025-11-00; online 2025-11-00]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Continuous Glucose Monitoring Data Analysis 2.0: Functional Data Pattern Recognition and Artificial Intelligence Applications.
Klonoff DC, Bergenstal RM, Cengiz E, ..., Ho CN, Healey E
J Diabetes Sci Technol 19 (6) 1515-1527 [2025-11-00; online 2025-08-14]
Daniel Espes SciLifeLab Fellow
DOI Crossref
Aquatic fungal diversity assessment through metagenomics is still limited to current databases
Sanyal A, Kluge M, Redondo MA, ..., Bertilsson S, Peura S
Limnol. Oceanogr. 70 (11) 3249-3260 [2025-11-00; online 2025-09-12]
Sarahi Garcia Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Allosteric control of the bacterial ClpC/ClpP protease and its hijacking by antibacterial peptides.
Jenne T, Engelhardt L, Baronaite I, ..., Carroni M, Mogk A
EMBO J. 44 (21) 6273-6296 [2025-11-00; online 2025-09-29]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
466 Cancer intrinsic protein neddylation reprograms macrophage metabolism to constrain immune checkpoint blockade therapy
Papakyriacou I, Lu Y, Bedos MR, ..., Puigvert JC, Mao Y
- - (-) A531-A531 [2025-11-00; online 2025-11-04]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response.
Lafranchi L, Raja GL, Arenas AM, ..., Branca RMM, Elsӓsser SJ
Nucleic Acids Res. 53 (20) - [2025-10-28; online 2025-11-09]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
Prodan-based solvatochromic probes for polarity imaging of organelles
Aknine N, Holban P, Ragaller F, ..., Sezgin E, Klymchenko AS
- - (-) - [2025-10-17; online 2025-10-17]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Association of estrogen receptor single nucleotide polymorphisms and perinatal depression.
Björvang RD, Gumbo LF, Årdahl A, ..., Fransson E, Skalkidou A
PLoS ONE 20 (10) e0334705 [2025-10-16; online 2025-10-16]
Erika Comasco SciLifeLab Fellow
DOI Crossref
“Universal Hyb-Seq kits capture considerable intraspecific variation: Less is more in herbarium-inclusive molecular ecology”
Woudstra Y, Quatela AS, Wagemaker NC, ..., Gravendeel B, Verhoeven KJ
- - (-) - [2025-10-15; online 2025-10-15]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Knowing is not enough; we must apply: the case for rigorous microRNA annotation standards.
Hackenberg M, Kalogeropoulos P, Peterson KJ, Friedländer MR, Fromm B
Nucleic Acids Res. 53 (19) - [2025-10-14; online 2025-10-21]
Marc Friedländer SciLifeLab Fellow
DOI Crossref
SURFR: genome-free discovery of cancer-unique small RNAs from cohort sequencing data
Kalogeropoulos P, Danilov K, Ulloa MA, ..., Hydbring P, Friedländer MR
- - (-) - [2025-10-07; online 2025-10-07]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Electrospun PLGA fibers with calcium phosphate nanoparticles: effects of nanoparticle crystallinity and carbonate content on osteogenic activity.
Suárez-López YDC, Ramachandran RV, Platania V, ..., Chatzinikolaidou M, Sotiriou GA
Biomater Sci 13 (20) 5863-5873 [2025-10-07; online 2025-10-07]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Widely-distributed freshwater microorganisms with streamlined genomes co-occur in cohorts with high abundance.
Rodríguez-Gijón A, Pacheco-Valenciana A, Milke F, ..., Rodriguez-R LM, Garcia SL
Sci Rep 15 (1) 34482 [2025-10-03; online 2025-10-03]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Genetic variation of the estrogen receptor and its association with depression and anxiety symptoms in young females.
Musaoglu MN, Olofsdotter S, Vadlin S, ..., Nieratschker V, Comasco E
Prog Neuropsychopharmacol Biol Psychiatry 142 (-) 111485 [2025-10-02; online 2025-09-05]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Plasma membrane labelling efficiency, internalization and partitioning of functionalized fluorescent lipids as a function of lipid structure.
Sezgin E
RSC Chem Biol 6 (10) 1640-1649 [2025-10-01; online 2025-09-01]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Differentially expressed transcripts associated with depressive symptoms during pregnancy and postpartum.
Björvang RD, Vrettou M, Bujanda Cundin X, ..., Comasco E, Skalkidou A
Mol. Psychiatry 30 (10) 4736-4748 [2025-10-00; online 2025-06-05]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Differences in the Fecal Metabolome of Autoimmune Pancreatitis Patients.
Dovhalyuk V, Yang F, Nikolic S, ..., Löhr JM, Globisch D
United European Gastroenterol J 13 (8) 1560-1570 [2025-10-00; online 2025-04-17]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
CD16A Shedding Regulates Innate Cell Engager-Induced Serial Killing by Natural Killer Cells.
Zambarda C, Guldevall K, Breunig C, ..., Koch J, Önfelt B
Eur. J. Immunol. 55 (10) e70078 [2025-10-00; online 2025-10-21]
Patrick Sandoz SciLifeLab Fellow
PubMed DOI Crossref
Alterations of the pancreas in type 1 diabetes - from prior to diagnosis to long-standing disease.
Missima NG, Hill H, Aioanei CS, Liss P, Espes D
Endocrine 90 (1) 140-148 [2025-10-00; online 2025-07-12]
Daniel Espes SciLifeLab Fellow
PubMed DOI Crossref
Maternal aggression driven by the transient mobilisation of a dormant hormone-sensitive circuit.
Stagkourakis S, Williams P, Spigolon G, ..., Fisone G, Broberger C
Nat Commun 16 (1) 8553 [2025-09-29; online 2025-09-29]
SciLifeLab Fellow Stefanos Stagkourakis
DOI Crossref
Targeting PKLR and lipogenic enzymes through JNK inhibition to develop a therapeutic strategy for MASLD and MASH
Mardinoglu A, Kim W, Li M, ..., Zhang C, Turkez H
- - (-) - [2025-09-25; online 2025-09-25]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
LipiGo: A Versatile DNA-Lipid Nanoparticle Hybrid for Precision Drug Delivery
Kadletz K, Kimna C, Reichenbach VK, ..., Elsner M, Ertürk A
- - (-) - [2025-09-18; online 2025-09-18]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity.
Motso A, Pelcman B, Kalinovich A, ..., Wright SC, Bengtsson T
Cell 188 (19) 5142-5156.e23 [2025-09-18; online 2025-06-23]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Impact of early-life human microbiota on the murine host metabolome: insights from a two-generation HMA mouse model and implications for allergic disease.
de Jong YA, Seren RM, Ramšak Marčeta V, ..., Qazi KR, Sverremark-Ekström E
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Adil Mardinoglu SciLifeLab Fellow
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Understanding the transport of drugs across biomimetic barriers of various phospholipid compositions using a combined experimental and computational approach.
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Synthesis of Two Neutrophil Elastase Inhibitors by Palladium-mediated [11C]cyanations
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POSTER: AML-570 Predictive Value of Microbiome and Metabolomic Biomarkers in Myeloid Neoplasms
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Clinical Lymphoma Myeloma and Leukemia 25 (-) S190 [2025-09-00; online 2025-09-00]
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Longitudinal big biological data in the AI era.
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Genomic studies in Linum shed light on the evolution of the distyly supergene and the molecular basis of convergent floral evolution.
Zervakis PI, Postel Z, Losvik A, ..., Churcher A, Slotte T
New Phytol. 247 (6) 2964-2981 [2025-09-00; online 2025-07-18]
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A Base-Mediated Rearrangement of the Benzylic 1,5-Hexadipyridynyl Moiety.
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Ruisheng Xiong SciLifeLab Fellow
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Chromogranin A and catestatin regulate pancreatic islet homeostasis, endocrine function, and neurotransmitter signaling.
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Gustaf Christoffersson SciLifeLab Fellow
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NAIP/NLRC4 inflammasome dynamics in murine enteroids are tuned by NAIP ligand concentration and epithelial cell differentiation.
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Cell Reports 44 (8) 116143 [2025-08-26; online 2025-08-20]
Mikael Sellin SciLifeLab Fellow
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Erdinc Sezgin Lucie Delemotte SciLifeLab Fellow
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The power of two: Combining imaging and sequencing as readouts for in vivo pooled genetic screens.
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Mol. Cell 85 (16) 3006-3008 [2025-08-21; online 2025-08-23]
Magda Bienko SciLifeLab Fellow
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Flame-made nanoparticles for magnetic hyperthermia and MRI in colorectal cancer theranostics.
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Alexandra Teleki SciLifeLab Fellow
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Translocations can drive expression changes of multiple genes in regulons covering entire chromosome arms.
Oncins A, Zaurin R, Toukabri H, ..., Oudelaar AM, Beekman R
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Magda Bienko SciLifeLab Fellow
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Screening scaffold proteins for improved functional delivery of luminal proteins using engineered extracellular vesicles.
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bioLUCID: quantifying batch and biological effect in single-cell transcriptomics by hypothesis-driven variance decomposition
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Jean Hausser SciLifeLab Fellow
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Whole-genome duplication increases genetic diversity and load in outcrossing Arabidopsis arenosa.
Vlček J, Hämälä T, Vives Cobo C, ..., Yant L, Kolář F
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Mikael Sellin SciLifeLab Fellow
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AEMB: efficient abundance estimation for metagenomic binning
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Kristoffer Sahlin SciLifeLab Fellow
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Sheathless Elasto-Inertial Focusing of Sub-25 Nm Particles in Straight Microchannels.
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Erdinc Sezgin SciLifeLab Fellow
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Mast Cell Phenotypic Heterogeneity Impacts the Interplay with Pathogenic Salmonella Typhimurium Bacteria.
von Beek C, Prensa GI, Andersson JHM, Pejler G, Sellin ME
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Mikael Sellin SciLifeLab Fellow
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Erik Benson Kristoffer Sahlin SciLifeLab Fellow
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Transcription of GABAA receptor subunits in circulating monocytes and association to emotional brain function in premenstrual dysphoric disorder.
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Erika Comasco SciLifeLab Fellow
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A U3 snoRNA is required for the regulation of chromatin dynamics and antiviral response in Drosophila melanogaster.
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Establishing a Malonyl-CoA Biosensor for the Two Model Cyanobacteria Synechocystis sp. PCC 6803 and Synechococcus elongatus PCC 7942.
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Paul Hudson SciLifeLab Fellow
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A Cyanobacterial Screening Platform for Rubisco Mutant Variants.
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Paul Hudson SciLifeLab Fellow
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Structure-based discovery of positive allosteric modulators of the A1 adenosine receptor.
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Jens Carlsson SciLifeLab Fellow
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PET imaging of platelet derived growth factor receptor β in lung fibrosis.
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Olof Eriksson SciLifeLab Fellow
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Anticancer effects and mechanisms of Pulsatilla chinensis, Bupleurum chinense and Polyporus umbellatus on human lung carcinoma and hepatoma cells.
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Adil Mardinoglu SciLifeLab Fellow
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Intestinal estrogen receptor beta modulates the murine colon tumor immune microenvironment.
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Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems.
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Multi-Omics biological embeddings for ML-models
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Adil Mardinoglu SciLifeLab Fellow
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High-throughput DNA melt measurements enable improved models of DNA folding thermodynamics.
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Emil Marklund SciLifeLab Fellow
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When numbers matter: Rethinking the role of gene duplication on short evolutionary timescales.
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American journal of botany 112 (7) e70072 [2025-07-00; online 2025-07-09]
Pascal Milesi SciLifeLab Fellow
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The value of mental science: we publish what matters.
Malhi GS, Adlington K, Al-Diwani A, ..., Zisman-Ilani Y, Fernandez-Egea E
Br J Psychiatry 227 (1) 429-433 [2025-07-00; online 2025-06-09]
Erika Comasco SciLifeLab Fellow
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Systematically identification of survival-associated eQTLs in a Japanese kidney cancer cohort.
Song X, Jin H, Li X, ..., Zhang C, Mardinoglu A
PLoS Genet 21 (7) e1011770 [2025-07-00; online 2025-07-07]
Adil Mardinoglu SciLifeLab Fellow
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Measuring plasma membrane fluidity using confocal microscopy.
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Erdinc Sezgin SciLifeLab Fellow
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Gut microbiota mediates SREBP-1c-driven hepatic lipogenesis and steatosis in response to zero-fat high-sucrose diet.
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Adil Mardinoglu SciLifeLab Fellow
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Genetic structure and diversity of the declining orchid Gymnadenia conopsea in Scandinavia: implications for conservation and management
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Pascal Milesi SciLifeLab Fellow
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Collaborative Duality of CircGLIS3(2) RNA and Protein in human Wound Repair.
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SciLifeLab Fellow Simon Elsässer
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A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen.
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Mikael Sellin SciLifeLab Fellow
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Pretreatment with estrogen enhances the therapeutic efficacy of cardiac progenitor cells and improves cardiac recovery in a failing heart model
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Erdinc Sezgin SciLifeLab Fellow
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The mitochondrial methylation potential gates mitoribosome assembly.
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Alexey Amunts SciLifeLab Fellow
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Investigating Inflammation and Tissue Remodeling in ILD with [ 11 C]NES and [ 68 Ga]Ga-FAPI-46 PET Imaging
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Olof Eriksson SciLifeLab Fellow
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Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D2 Receptor.
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Jens Carlsson SciLifeLab Fellow
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The pcnB gene sustains Shigella flexneri virulence
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Mikael Sellin SciLifeLab Fellow
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Exploring impacts of long-COVID-19 on the lungs: A triad of PET scans for perfusion, inflammation and tissue remodeling
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Olof Eriksson SciLifeLab Fellow
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RNA transcripts regulate G-quadruplex landscapes through G-loop formation.
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Science (New York, N.Y.) 388 (6752) 1225-1231 [2025-06-12; online 2025-06-12]
SciLifeLab Fellow Simon Elsässer
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Revised Diffusion Law Permits Quantitative Nanoscale Characterization of Membrane Organization.
Svobodová B, Št'astný D, Blom H, ..., Hof M, Šachl R
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Erdinc Sezgin SciLifeLab Fellow
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Flame-Made Doped Iron Oxide Nanoparticles as Tracers for Magnetic Particle Imaging.
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Chem Mater 37 (11) 4071-4084 [2025-06-10; online 2025-05-20]
Alexandra Teleki SciLifeLab Fellow
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A resource for whole-body gene expression map of human tissues based on integration of single cell and bulk transcriptomics.
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Genome Biol. 26 (1) 152 [2025-06-03; online 2025-06-03]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
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Trajectories and dimensional phenotypes of depressive symptoms throughout pregnancy and postpartum in relation to prior premenstrual symptoms.
Schleimann-Jensen E, Sundström-Poromaa I, Meltzer-Brody S, ..., Skalkidou A, Comasco E
Br J Psychiatry 226 (6) 401-409 [2025-06-00; online 2025-06-20]
Erika Comasco SciLifeLab Fellow
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Subjective, behavioural and physiological correlates of stress in women using hormonal contraceptives.
Bürger Z, Kordowich C, Kübbeler J, ..., Derntl B, Kogler L
Br J Psychiatry 226 (6) 392-400 [2025-06-00; online 2025-06-13]
Erika Comasco SciLifeLab Fellow
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Psychiatric symptoms on the ovarian hormone roller-coaster.
Comasco E, Epperson CN, Kulkarni J
Br J Psychiatry 226 (6) 329-330 [2025-06-00; online 2025-06-18]
Erika Comasco SciLifeLab Fellow
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NAT2 activity increases cytotoxicity of anthracycline antibiotics and HDAC inhibitors.
Rameika N, Tsiara I, Zhang X, ..., Globisch D, Sjöblom T
Biochim Biophys Acta Mol Basis Dis 1871 (5) 167755 [2025-06-00; online 2025-03-13]
Daniel Globisch SciLifeLab Fellow
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Magnetic microfiber hyperthermia for synergistic antimicrobial activity against methicillin-resistant Staphylococcus aureus.
Ansari SR, Grimm D, Ramachandran RV, ..., Sotiriou GA, Teleki A
Mater Today Bio 32 (-) 101862 [2025-06-00; online 2025-05-12]
Alexandra Teleki SciLifeLab Fellow
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Direct and indirect pathways linking the Lon protease to motility behaviors in the pathogen Pseudomonas aeruginosa.
Kallazhi A, Rahman A, Römling U, Jonas K
PLoS Pathog 21 (6) e1013288 [2025-06-00; online 2025-06-25]
Kristina Jonas SciLifeLab Fellow
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A universal language for finding mass spectrometry data patterns.
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Nat. Methods 22 (6) 1247-1254 [2025-06-00; online 2025-05-12]
Daniel Globisch SciLifeLab Fellow
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Widespread potential for phototrophy and convergent reduction of lifecycle complexity in the dimorphic order Caulobacterales
Hallgren J, Dharamshi JE, Rodríguez-Gijón A, ..., Garcia SL, Jonas K
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Kristina Jonas Sarahi Garcia SciLifeLab Fellow
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Ribosomes modulate transcriptome abundance via generalized frameshift and out-of-frame mRNA decay.
Zhang Y, Nersisyan L, Fürst E, ..., Piazza I, Pelechano V
Mol. Cell 85 (10) 2017-2031.e7 [2025-05-15; online 2025-05-17]
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Cell membranes sustain phospholipid imbalance via cholesterol asymmetry.
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Cell 188 (10) 2586-2602.e24 [2025-05-15; online 2025-04-02]
DDLS Fellow Erdinc Sezgin Milka Doktorova SciLifeLab Fellow
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Extensively acquired antimicrobial-resistant bacteria restructure the individual microbial community in post-antibiotic conditions.
Baek JW, Lim S, Park N, ..., Koh A, Lee S
NPJ Biofilms Microbiomes 11 (1) 78 [2025-05-14; online 2025-05-14]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Plasma membrane labelling efficiency, internalization and partitioning of functionalized fluorescent lipids as a function of lipid structure
Sezgin E
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Erdinc Sezgin SciLifeLab Fellow
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Evaluation of unsupervised learning algorithms for the classification of behavior from pose estimation data.
Mlost J, Dawli R, Liu X, Costa AR, Pollak Dorocic I
Patterns (N Y) 6 (5) 101237 [2025-05-09; online 2025-04-22]
Iskra Pollak Dorocic SciLifeLab Fellow
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INLAomics for Scalable and Interpretable Spatial Multiomic Data Integration.
Arnroth L, Vickovic S
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Sanja Vickovic SciLifeLab Fellow
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De novo clustering of large long-read transcriptome datasets with isONclust3.
Petri AJ, Sahlin K
Bioinformatics 41 (5) - [2025-05-06; online 2025-04-23]
Kristoffer Sahlin SciLifeLab Fellow
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Cryo-EM structure of the human monocarboxylate transporter 10.
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Lucie Delemotte SciLifeLab Fellow
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The multifaceted role of post-translational modifications of LSD1 in cellular processes and disease pathogenesis.
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Genes Dis 12 (3) 101307 [2025-05-00; online 2024-04-15]
Adil Mardinoglu SciLifeLab Fellow
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The overlooked trio: sleep duration, sampling time and physical exercise alter levels of olink-assessed blood biomarkers of cardiovascular risk.
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Biomark Res 13 (1) 67 [2025-04-29; online 2025-04-29]
Daniel Espes SciLifeLab Fellow
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Multi-cellular phenotypic dynamics during the progression of breast tumors
Gsell L, Watson SS, Sutevski I, ..., Joyce JA, Hausser J
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Jean Hausser SciLifeLab Fellow
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Low anabolic independence emerges when cultivating more than three bacterial species together
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Sarahi Garcia SciLifeLab Fellow
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Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery.
Beretta C, Dakhel A, Eltom K, ..., Michno WP, Erlandsson A
J Neuroinflammation 22 (1) 117 [2025-04-24; online 2025-04-24]
SciLifeLab Fellow Wojciech Michno
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Abstract 176: Simultaneous spatial characterisation of copy number change and immune cell profiling using DNA FISH and multiplexed immunofluorescence
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Magda Bienko SciLifeLab Fellow
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Nanobinders for Synaptotagmin 1 enable the analysis of synaptic vesicle dynamics in rodent and human models
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Ilaria Testa SciLifeLab Fellow
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Genomic studies in Linum shed light on the evolution of the distyly supergene and the molecular basis of convergent floral evolution
Zervakis PI, Postel Z, Losvik A, ..., Churcher A, Slotte T
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IntegrAlign: A comprehensive tool for multi-immunofluorescence panel integration through image alignment
Hermet L, Laoubi L, Scavino M, ..., Caux C, Hubert M
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Erika Comasco SciLifeLab Fellow
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Cheung P, Persson J, Zhang B, ..., Löfblom J, Eriksson O
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Martin G, Rissanen AJ, Garcia SL, Peura S
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Sarahi Garcia Sari Peura SciLifeLab Fellow
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ISME Commun 5 (1) ycaf136 [2025-01-00; online 2025-08-29]
Sarahi Garcia SciLifeLab Fellow
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Sarahi Garcia SciLifeLab Fellow
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EBioMedicine 111 (-) 105495 [2025-01-00; online 2024-12-10]
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Year 2024

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Complete genome sequences of the prosthecate dimorphic bacteria Brevundimonas intermedia CB63T and Brevundimonas staleyi FWC43T.
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XRN1 supplies free nucleotides to feed alphavirus replication
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Doktorova M, Symons JL, Zhang X, ..., Levental KR, Levental I
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Weber F, Axmann M, Sezgin E, ..., Stangl H, Plochberger B
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Improved Localization of Insulinomas Using 68Ga-NODAGA-Exendin-4 PET/CT.
Boss M, Eriksson O, Mikkola K, ..., Hermans J, Gotthardt M
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 65 (12) 1959-1964 [2024-12-03; online 2024-12-03]
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Jin H, Kim W, Yuan M, ..., Zhang C, Mardinoglu A
Front Immunol 15 (-) 1446453 [2024-12-03; online 2024-12-03]
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Exploring BPA alternatives - Environmental levels and toxicity review.
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Deconwolf enables high-performance deconvolution of widefield fluorescence microscopy images.
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Virtual special issue of Nordic POP: Patient-oriented products.
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Alexey Amunts SciLifeLab Fellow
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Malat1 affects transcription and splicing through distinct pathways in mouse embryonic stem cells.
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Macrophages upregulate mural cell-like markers and support healing of ischemic injury by adopting functions important for vascular support.
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Design and synthesis of novel JNK inhibitors targeting liver pyruvate kinase for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma.
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Adil Mardinoglu SciLifeLab Fellow
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The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site.
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2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives.
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Adil Mardinoglu SciLifeLab Fellow
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Daniel Globisch SciLifeLab Fellow
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Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk.
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Alexey Amunts SciLifeLab Fellow
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Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule.
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Olof Eriksson SciLifeLab Fellow
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Mol. Cell 84 (10) 1932-1947.e10 [2024-05-16; online 2024-05-03]
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Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders.
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Iron oxide nanoparticles for treatment and diagnosis of chronic inflammatory diseases: A systematic review.
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MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations.
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Lucie Delemotte SciLifeLab Fellow
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Genetic Causes and Genomic Consequences of Breakdown of Distyly in Linum trigynum.
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Mikael Sellin SciLifeLab Fellow
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Comparative genomics of Ascetosporea gives new insight into the evolutionary basis for animal parasitism in Rhizaria.
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CopyVAE: a variational autoencoder-based approach for copy number variation inference using single-cell transcriptomics.
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Camilla Engblom SciLifeLab Fellow
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Male-transmitted transgenerational effects of the herbicide linuron on DNA methylation profiles in Xenopus tropicalis brain and testis.
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Sci. Total Environ. 923 (-) 170949 [2024-05-01; online 2024-02-15]
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White matter volume and treatment with selective progesterone receptor modulator in patients with premenstrual dysphoric disorder.
Kaltsouni E, Wikström J, Lanzenberger R, Sundström-Poromaa I, Comasco E
Psychoneuroendocrinology 163 (-) 106977 [2024-05-00; online 2024-01-22]
Erika Comasco SciLifeLab Fellow
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Super-sectioning with multi-sheet reversible saturable optical fluorescence transitions (RESOLFT) microscopy.
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Nat. Methods 21 (5) 882-888 [2024-05-00; online 2024-02-23]
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Generation of Anterior Segment of the Eye Cells from hiPSCs in Microfluidic Platforms.
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Adil Mardinoglu SciLifeLab Fellow
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Cellular energy regulates mRNA degradation in a codon-specific manner.
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Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer.
Papakyriacou I, Kutkaite G, Rúbies Bedós M, ..., Menden MP, Mao Y
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Tissue and cellular spatiotemporal dynamics in colon aging.
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Sanja Vickovic SciLifeLab Fellow
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High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue.
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Magda Bienko SciLifeLab Fellow
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Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases.
Altay O, Yang H, Yildirim S, ..., Turkez H, Mardinoglu A
Biomedicines 12 (4) - [2024-04-22; online 2024-04-22]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Author Correction: scCircle-seq unveils the diversity and complexity of extrachromosomal circular DNAs in single cells.
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Nat Commun 15 (1) 3390 [2024-04-22; online 2024-04-22]
Magda Bienko SciLifeLab Fellow
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Microenvironmental reorganization in brain tumors following radiotherapy and recurrence revealed by hyperplexed immunofluorescence imaging.
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Nat Commun 15 (1) 3226 [2024-04-15; online 2024-04-15]
Jean Hausser SciLifeLab Fellow
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Evolution of microRNAs in Amoebozoa and implications for the origin of multicellularity.
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Nucleic Acids Res. 52 (6) 3121-3136 [2024-04-12; online 2024-02-20]
Marc Friedländer SciLifeLab Fellow
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Drug repositioning for immunotherapy in breast cancer using single-cell analysis.
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NPJ Syst Biol Appl 10 (1) 37 [2024-04-08; online 2024-04-08]
Adil Mardinoglu SciLifeLab Fellow
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Sulfone-based human liver pyruvate kinase inhibitors - Design, synthesis and in vitro bioactivity.
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Eur J Med Chem 269 (-) 116306 [2024-04-05; online 2024-03-05]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Identification of New Ketamine Metabolites and Their Detailed Distribution in the Mammalian Brain.
Vallianatou T, de Souza Anselmo C, Tsiara I, ..., Lundgaard I, Globisch D
ACS Chem Neurosci 15 (7) 1335-1341 [2024-04-03; online 2024-03-20]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Rücktitelbild: Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4‐Nitrophenyl‐2‐azirine (Angew. Chem. 14/2024)
Lin W, Gerullat L, Braadland PR, ..., Hov JR, Globisch D
Angewandte Chemie 136 (14) - [2024-04-02; online 2024-02-29]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4‐Nitrophenyl‐2‐azirine
Lin W, Gerullat L, Braadland PR, ..., Hov JR, Globisch D
Angewandte Chemie 136 (14) - [2024-04-02; online 2024-01-31]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4-Nitrophenyl-2H-azirine.
Lin W, Gerullat L, Braadland PR, ..., Hov JR, Globisch D
Angew. Chem. Int. Ed. Engl. 63 (14) e202318579 [2024-04-02; online 2024-01-31]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Back Cover: Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4‐Nitrophenyl‐2‐azirine (Angew. Chem. Int. Ed. 14/2024)
Lin W, Gerullat L, Braadland PR, ..., Hov JR, Globisch D
Angewandte Chemie International Edition 63 (14) - [2024-04-02; online 2024-02-29]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
A comparison between different human hepatocyte models reveals profound differences in net glucose production, lipid composition and metabolism in vitro.
Bonanini F, Singh M, Yang H, ..., Mardinoglu A, Hankemeier T
Exp. Cell Res. 437 (1) 114008 [2024-04-01; online 2024-03-16]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Unexpected effect of halogenation on the water solubility of small organic compounds.
Zhang J, Gulyás KV, Li J, ..., Zhu W, Xu Z
Comput Biol Med 172 (-) 108209 [2024-04-00; online 2024-02-28]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Terlipressin therapy is associated with increased risk of colonisation with multidrug-resistant bacteria in patients with decompensated cirrhosis.
Mücke MM, Hernández-Tejero M, Gu W, ..., Trebicka J, MICROB-PREDICT and PREDICT Study Group of the EASL-CLIF Consortium
Aliment. Pharmacol. Ther. 59 (7) 877-888 [2024-04-00; online 2024-02-27]
Saeed Shoaie SciLifeLab Fellow
DOI Crossref
In Vitro Cytotoxic, Genotoxic, Embryotoxic and Oxidative Damage Potentials by Empagliflozin
Kenan Cadirci , Turkez H, Tozlu OO, ..., Emsen B, Mardinoglu A
Biol Bull Russ Acad Sci 51 (2) 243-250 [2024-04-00; online 2024-02-09]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Hybridization mediated range expansion and climate change resilience in two keystone tree species of boreal forests.
Karunarathne P, Zhou Q, Lascoux M, Milesi P
Glob Chang Biol 30 (4) e17262 [2024-04-00; online 2024-03-28]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
High-throughput measurement of the content and properties of nano-sized bioparticles with single-particle profiler.
Sych T, Schlegel J, Barriga HMG, ..., Stevens MM, Sezgin E
Nat. Biotechnol. 42 (4) 587-590 [2024-04-00; online 2023-06-12]
Daniel Fürth Erdinc Sezgin SciLifeLab Fellow
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Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.
Sommerauer C, Gallardo-Dodd CJ, Savva C, ..., Williams C, Kutter C
Mol Syst Biol 20 (4) 374-402 [2024-04-00; online 2024-03-08]
Claudia Kutter Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution.
Ernst C, Andreassen PR, Giger GH, ..., Hardt WD, Vorholt JA
PLoS Biol. 22 (4) e3002597 [2024-04-00; online 2024-04-29]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Despite structural identity, ace-1 heterogenous duplication resistance alleles are quite diverse in Anopheles mosquitoes.
Claret JL, Di-Liegro M, Namias A, ..., Milesi P, Labbé P
Heredity (Edinb) 132 (4) 179-191 [2024-04-00; online 2024-01-27]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Gene-expression memory-based prediction of cell lineages from scRNA-seq datasets.
Eisele AS, Tarbier M, Dormann AA, Pelechano V, Suter DM
Nat Commun 15 (1) 2744 [2024-03-29; online 2024-03-29]
DDLS Fellow Marcel Tarbier SciLifeLab Fellow
PubMed DOI Crossref
Designing efficient randstrobes for sequence similarity analyses.
Karami M, Soltani Mohammadi A, Martin M, ..., Patro R, Sahlin K
Bioinformatics 40 (4) - [2024-03-29; online 2024-04-05]
Kristoffer Sahlin SciLifeLab Fellow
DOI Crossref
Nematocida displodere Mechanosensitive Ion Channel of Small Conductance 2 assembles into a unique 6-channel super-structure in vitro
Berg A, Berntsson RPA, Barandun J
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Jonas Barandun SciLifeLab Fellow
DOI Crossref
Landscape of microRNA and target expression variation and covariation in single mouse embryonic stem cells
Tarbier M, Mackowiak SD, Sekar V, ..., Biryukova I, Friedländer MR
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DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
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Salmonella T3SS-2 virulence enhances gut-luminal colonization by enabling chemotaxis-dependent exploitation of intestinal inflammation.
Gül E, Huuskonen J, Abi Younes A, ..., Bakkeren E, Hardt WD
Cell Reports 43 (3) 113925 [2024-03-26; online 2024-03-07]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis.
Bergman S, Andresen L, Kjellin J, ..., Sellin ME, Holmqvist E
mSphere 9 (3) e0001824 [2024-03-26; online 2024-02-27]
Mikael Sellin SciLifeLab Fellow
DOI Crossref
NEDD8 loss causes cancer vulnerability to immune checkpoint blockade in triple-negative breast cancer
Mao Y, Papakyriacou I, Kutkaite G, ..., Alford L, Menden M
- - (-) - [2024-03-25; online 2024-03-25]
SciLifeLab Fellow Yumeng Mao
DOI Crossref
Chloroplastic ascorbate acts as a regulatory hub in plant metabolism regardless of oxidative stress
Tóth D, Tengölics R, Aarabi F, ..., Papp B, Tóth SZ
- - (-) - [2024-03-18; online 2024-03-18]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Boundary cap neural crest stem cells promote angiogenesis after transplantation to avulsed dorsal roots in mice and induce migration of endothelial cells in 3D printed scaffolds.
Trolle C, Han Y, Mutt SJ, Christoffersson G, Kozlova EN
Neurosci. Lett. 826 (-) 137724 [2024-03-15; online 2024-03-11]
Gustaf Christoffersson SciLifeLab Fellow
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Identification of a new gregarine parasite associated with mass mortality events of freshwater pearl mussels (Margaritifera margaritifera) in Sweden.
Alfjorden A, Onut-Brännström I, Wengström N, ..., Persson BD, Burki F
J. Eukaryot. Microbiol. 71 (3) e13021 [2024-03-13; online 2024-03-13]
Fabien Burki SciLifeLab Fellow
DOI Crossref
Ribosomes modulate transcriptome abundance via generalized frameshift and out-of-frame mRNA decay
Zhang Y, Nersisyan L, Fürst E, ..., Piazza I, Pelechano V
- - (-) - [2024-03-12; online 2024-03-12]
SciLifeLab Fellow
PubMed DOI Crossref
Quantifying Fluorescence Lifetime Responsiveness of Environment-Sensitive Probes for Membrane Fluidity Measurements.
Ragaller F, Sjule E, Urem YB, ..., Blom H, Sezgin E
J Phys Chem B 128 (9) 2154-2167 [2024-03-07; online 2024-02-28]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
The Calvin Benson cycle in bacteria: New insights from systems biology.
Hudson EP
Semin. Cell Dev. Biol. 155 (Pt A) 71-83 [2024-03-01; online 2023-03-29]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
The association of the RSC remodeler complex with chromatin is influenced by the prefoldin-like Bud27 and determines nucleosome positioning and polyadenylation sites usage in Saccharomyces cerevisiae.
Cuevas-Bermúdez A, Martínez-Fernández V, Garrido-Godino AI, ..., Pelechano V, Navarro F
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1867 (1) 194995 [2024-03-00; online 2023-11-13]
SciLifeLab Fellow
PubMed DOI Crossref
PACMan: A software package for automated single-cell chlorophyll fluorometry.
Pontén O, Xiao L, Kutter J, ..., Wählby C, Behrendt L
Cytometry A 105 (3) 203-213 [2024-03-00; online 2023-10-20]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Amyloid-β deposits in human astrocytes contain truncated and highly resistant proteoforms.
Beretta C, Svensson E, Dakhel A, ..., Michno W, Erlandsson A
Mol Cell Neurosci 128 (-) 103916 [2024-03-00; online 2024-01-19]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
scCircle-seq unveils the diversity and complexity of extrachromosomal circular DNAs in single cells.
Chen JP, Diekmann C, Wu H, ..., Bienko M, Crosetto N
Nat Commun 15 (1) 1768 [2024-02-27; online 2024-02-27]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Predictive biomarkers of rapidly developing insulin deficiency in children with type 1 diabetes.
Lundkvist P, Grönberg A, Carlsson PO, Ludvigsson J, Espes D
BMJ Open Diabetes Res Care 12 (1) - [2024-02-27; online 2024-02-27]
Daniel Espes SciLifeLab Fellow
PubMed DOI Crossref
Equine enteroid-derived monolayers recapitulate key features of parasitic intestinal nematode infection.
Hellman S, Martin F, Tydén E, ..., Svedberg P, Fossum C
Vet Res 55 (1) 25 [2024-02-27; online 2024-02-27]
Mikael Sellin SciLifeLab Fellow
DOI Crossref
The energy metabolism of Cupriavidus necator in different trophic conditions
Jahn M, Crang N, Gynnå AH, ..., Charpentier E, Hudson EP
- - (-) - [2024-02-26; online 2024-02-26]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Spatial Neurolipidomics at the Single Amyloid-β Plaque Level in Postmortem Human Alzheimer's Disease Brain.
Michno W, Bowman A, Jha D, ..., Heeren RMA, Hanrieder J
ACS Chem Neurosci 15 (4) 877-888 [2024-02-21; online 2024-02-01]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Applying a modified systematic review and integrated assessment framework (SYRINA) - a case study on triphenyl phosphate.
Bui TT, Aasa J, Abass K, ..., Yost E, Rudén C
Environ Sci Process Impacts 26 (2) 380-399 [2024-02-21; online 2024-02-21]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma.
Sainero-Alcolado L, Garde-Lapido E, Snaebjörnsson MT, ..., Schulze A, Arsenian-Henriksson M
Proc. Natl. Acad. Sci. U.S.A. 121 (7) e2310479121 [2024-02-13; online 2024-02-09]
SciLifeLab Fellow
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Most axonal mitochondria in cortical pyramidal neurons lack mitochondrial DNA and consume ATP.
Hirabayashi Y, Lewis TL, Du Y, ..., Testa I, Polleux F
bioRxiv - (-) - [2024-02-13; online 2024-02-13]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Editorial: Footprints of immune cells in the type 1 diabetic pancreas, volume II.
Christoffersson G, Fousteri G
Front Endocrinol (Lausanne) 15 (-) 1367245 [2024-02-06; online 2024-02-06]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Single-molecule chromatin configurations link transcription factor binding to expression in human cells.
Doughty BR, Hinks MM, Schaepe JM, ..., Bintu L, Greenleaf WJ
bioRxiv - (-) - [2024-02-04; online 2024-02-04]
Emil Marklund SciLifeLab Fellow
PubMed DOI Crossref
Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1.
Bacic L, Gaullier G, Mohapatra J, ..., Sabantsev A, Deindl S
Nat Commun 15 (1) 1000 [2024-02-02; online 2024-02-02]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis.
Puuvuori E, Shen Y, Hulsart-Billström G, ..., Wermeling F, Eriksson O
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 65 (2) 294-299 [2024-02-01; online 2024-02-01]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Ultrastructural insights into the microsporidian infection apparatus reveal the kinetics and morphological transitions of polar tube and cargo during host cell invasion.
Sharma H, Jespersen N, Ehrenbolger K, Carlson LA, Barandun J
PLoS Biol. 22 (2) e3002533 [2024-02-00; online 2024-02-29]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Stress biology: Complexity and multifariousness in health and disease.
Mayer MP, Blair L, Blatch GL, ..., Wang SXY, Zininga T
Cell Stress Chaperones 29 (1) 143-157 [2024-02-00; online 2024-02-03]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Nutritional control of bacterial DNA replication.
Hallgren J, Jonas K
Curr Opin Microbiol 77 (-) 102403 [2024-02-00; online 2023-11-30]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Intrinsic deletion at 10q23.31, including the PTEN gene locus, is aggravated upon CRISPR-Cas9-mediated genome engineering in HAP1 cells mimicking cancer profiles.
Geng K, Merino LG, Veiga RG, ..., Brinkman EK, Kutter C
Life Sci. Alliance 7 (2) - [2024-02-00; online 2023-11-20]
Claudia Kutter SciLifeLab Fellow
DOI Crossref
High-throughput and multi-parametric biophysical cell phenotyping with smart probes
Gurdap C, Andronico L, Cowgill J, Sezgin E
Biophysical Journal 123 (3) 449a-450a [2024-02-00; online 2024-02-00]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors.
Menon I, Sych T, Son Y, ..., Levitz J, Menon AK
J Biol Chem 300 (2) 105649 [2024-02-00; online 2024-01-16]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection.
von Beek C, Fahlgren A, Geiser P, ..., Pejler G, Sellin ME
Nat Commun 15 (1) 904 [2024-01-30; online 2024-01-30]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Remodeling of the human skeletal muscle proteome found after long-term endurance training but not after strength training.
Emanuelsson EB, Arif M, Reitzner SM, ..., Sundberg CJ, Chapman MA
iScience 27 (1) 108638 [2024-01-19; online 2023-12-05]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.
Ast T, Itoh Y, Sadre S, ..., Amunts A, Mootha VK
Mol. Cell 84 (2) 359-374.e8 [2024-01-18; online 2024-01-09]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Plasma membrane order maps functional diversity in immune cells
Andronico LA, Gurdap CO, Arora A, ..., Brodin P, Sezgin E
- - (-) - [2024-01-16; online 2024-01-16]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction.
Clatot J, Currin CB, Liang Q, ..., Covarrubias M, Goldberg EM
Proc. Natl. Acad. Sci. U.S.A. 121 (3) e2307776121 [2024-01-16; online 2024-01-09]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Impaired spermatogenesis and associated endocrine effects of azole fungicides in peripubertal Xenopus tropicalis.
Svanholm S, Brouard V, Roza M, ..., Karlsson O, Berg C
Ecotoxicology and Environmental Safety 270 (-) 115876 [2024-01-15; online 2023-12-27]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis.
Drexhage LZ, Zhang S, Dupont M, ..., Karaji N, Sattentau QJ
Nat Commun 15 (1) 541 [2024-01-15; online 2024-01-15]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Introduction of a fatty acid chain modification to prolong circulatory half-life of a radioligand towards glucose-dependent insulinotropic polypeptide receptor.
Khalil A, Hakhverdyan S, Cheung P, ..., Eriksson O, Velikyan I
Nucl. Med. Biol. 128-129 (-) 108876 [2024-01-10; online 2024-01-10]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Multilayer DNA Origami with Terminal Interfaces That Are Flat and Wide-Area.
Kilwing L, Lill P, Nathwani B, ..., Liedl T, Shih WM
ACS Nano 18 (1) 885-893 [2024-01-09; online 2023-12-18]
Erik Benson SciLifeLab Fellow
DOI Crossref
High-Throughput DNA melt measurements enable improved models of DNA folding thermodynamics
Ke Y, Sharma E, Wayment-Steele HK, ..., Marklund E, Greenleaf WJ
- - (-) - [2024-01-09; online 2024-01-09]
Emil Marklund SciLifeLab Fellow
PubMed DOI Crossref
Geographic population structure and distinct intra-population dynamics of globally abundant freshwater bacteria.
Hoetzinger M, Hahn MW, Andersson LY, ..., Puente-Sánchez F, Bertilsson S
ISME J 18 (1) - [2024-01-08; online 2024-07-04]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors.
Menon I, Sych T, Son Y, ..., Levitz J, Menon AK
bioRxiv - (-) - [2024-01-05; online 2024-01-05]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Compartmentalizing damaged DNA: A double-edged sword.
Georgiades E, Crosetto N, Bienko M
Mol. Cell 84 (1) 12-13 [2024-01-04; online 2024-01-06]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
A Conserved Ribosomal Protein Has Entirely Dissimilar Structures in Different Organisms.
Schierholz L, Brown CR, Helena-Bueno K, ..., Barandun J, Melnikov SV
Mol. Biol. Evol. 41 (1) - [2024-01-03; online 2023-11-21]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Functional annotation of a divergent genome using sequence and structure-based similarity.
Svedberg D, Winiger RR, Berg A, ..., Vossbrinck CR, Barandun J
BMC Genomics 25 (1) 6 [2024-01-02; online 2024-01-02]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Tuning of CHO secretional machinery improve activity of secreted therapeutic sulfatase 150-fold.
Thalén NB, Barzadd MM, Lundqvist M, ..., Sandegren A, Rockberg J
Metab. Eng. 81 (-) 157-166 [2024-01-00; online 2023-12-09]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes.
Vyakaranam AR, Mahamed MM, Hellman P, ..., Christoffersson G, Sundin A
Diabetologia 67 (1) 199-208 [2024-01-00; online 2023-11-07]
Daniel Espes Gustaf Christoffersson Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Molecular profiling of high-level athlete skeletal muscle after acute endurance or resistance exercise - A systems biology approach.
Reitzner SM, Emanuelsson EB, Arif M, ..., Chapman MA, Sundberg CJ
Mol Metab 79 (-) 101857 [2024-01-00; online 2023-12-21]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Enrichment of different taxa of the enigmatic candidate phyla radiation bacteria using a novel picolitre droplet technique.
Man DKW, Hermans SM, Taubert M, ..., Küsel K, Rosenbaum MA
ISME Commun 4 (1) ycae080 [2024-01-00; online 2024-06-21]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Electroencephalography findings in menstrually-related mood disorders: A critical review.
Kaltsouni E, Schmidt F, Zsido RG, ..., Sumner RL, Comasco E
Front Neuroendocrinol 72 (-) 101120 [2024-01-00; online 2024-01-02]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Transfer Learning-Assisted Inverse Modeling in Nanophotonics Based on Mixture Density Networks
Cheng L, Singh P, Ferranti F
IEEE Access 12 (-) 55218-55224 [2024-00-00; online 2024-00-00]
Prashant Singh SciLifeLab Fellow
DOI Crossref
Multi-Tissue Network Analysis Reveals the Effect of JNK Inhibition on Dietary Sucrose-Induced Metabolic Dysfunction in Rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
- - (-) - [2024-00-00; online 2024-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Integrative Proteo-Transcriptomic Characterization of Advanced Fibrosis in Chronic Liver Disease Across Etiologies
Yang H, Atak D, Yuan M, ..., Mardinoglu A, Zeybel M
- - (-) - [2024-00-00; online 2024-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Chromosome-Scale Genome Assembly Reveals How Repeat Elements Shape Non-Coding RNA Landscapes Active During Newt Limb Regeneration
Brown T, Mishra K, Elewa A, ..., Yun MH, Simon A
- - (-) - [2024-00-00; online 2024-00-00]
Marc Friedländer SciLifeLab Fellow
DOI Crossref
Adaptive RESOLFT microscopy
Lin R, Testa I
- - (-) OW1F.1 [2024-00-00; online 2024-00-00]
Ilaria Testa SciLifeLab Fellow

Year 2023

PubMed DOI Crossref
Drug Synergism of Anticancer Action in Combination with Favipiravir and Paclitaxel on Neuroblastoma Cells.
Turkez H, Arslan ME, Selvitopi H, ..., Oner S, Mardinoglu A
Medicina (Kaunas) 60 (1) - [2023-12-30; online 2023-12-30]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
RNA Pol II Assembly Affects ncRNA Expression.
Garrido-Godino AI, Gupta I, Pelechano V, Navarro F
Int J Mol Sci 25 (1) - [2023-12-29; online 2023-12-29]
SciLifeLab Fellow
PubMed DOI Crossref
Blue-shift photoconversion of near-infrared fluorescent proteins for labeling and tracking in living cells and organisms.
Pennacchietti F, Alvelid J, Morales RA, ..., Verkhusha VV, Testa I
Nat Commun 14 (1) 8402 [2023-12-19; online 2023-12-19]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Protein-Decorated Microbubbles for Ultrasound-Mediated Cell Surface Manipulation.
Brans VA, Gray MD, Sezgin E, Stride EPJ
ACS Appl Bio Mater 6 (12) 5746-5758 [2023-12-18; online 2023-12-04]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells.
Cheung P, Thorngren J, Zhang B, ..., Lau J, Eriksson O
EJNMMI Res 13 (1) 107 [2023-12-15; online 2023-12-15]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Variability in single-cell oxygen consumption kinetics
Botte E, Cui Y, Magliaro C, ..., Behrendt L, Ahluwalia A
- - (-) - [2023-12-11; online 2023-12-11]
Lars Behrendt SciLifeLab Fellow
DOI Crossref
Microbial metabolic specificity controls pelagic lipid export efficiency
Behrendt L, Alcolombri U, Hunter JE, ..., Stocker R, Van Mooy BAS
- - (-) - [2023-12-10; online 2023-12-10]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Spatial transcriptomics of B cell and T cell receptors reveals lymphocyte clonal dynamics.
Engblom C, Thrane K, Lin Q, ..., Lundeberg J, Frisén J
Science (New York, N.Y.) 382 (6675) eadf8486 [2023-12-08; online 2023-12-08]
Camilla Engblom SciLifeLab Fellow
PubMed DOI Crossref
Establishment of microbial model communities capable of removing trace organic chemicals for biotransformation mechanisms research.
Cao L, Garcia SL, Wurzbacher C
Microb Cell Fact 22 (1) 245 [2023-12-02; online 2023-12-02]
Sarahi Garcia SciLifeLab Fellow
DOI Crossref
RNA Pol II Assembly Affects ncRNA Expression
Garrido-Godino AI, Gupta I, Pelechano V, Navarro F
- - (-) - [2023-12-01; online 2023-12-01]
SciLifeLab Fellow
PubMed DOI Crossref
Subtype-specific modulation of human KV 7 channels by the anticonvulsant cannabidiol through a lipid-exposed pore-domain site.
Pökl M, Sridhar A, Frampton DJA, ..., Delemotte L, Liin SI
Br J Pharmacol 180 (23) 2956-2972 [2023-12-00; online 2023-07-27]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Metabolic exchanges are ubiquitous in natural microbial communities.
Kost C, Patil KR, Friedman J, Garcia SL, Ralser M
Nat. Microbiol 8 (12) 2244-2252 [2023-12-00; online 2023-11-23]
Sarahi Garcia SciLifeLab Fellow
DOI Crossref
Exploring Gut Microbiota Metabolism—New Chemical Biology Tools for Metabolomics Analysis
Dovhalyuk V, Kaur A, Lin W, ..., Mwasambu S, Globisch D
- - (-) 64 [2023-11-29; online 2023-11-29]
Daniel Globisch SciLifeLab Fellow
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Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice.
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J Colloid Interface Sci 650 (Pt B) 1253-1264 [2023-11-15; online 2023-07-10]
Alexandra Teleki SciLifeLab Fellow
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Gouleni N, Di Rienzo A, Yılmaz A, ..., Vassiliou S, Cacciatore I
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Adil Mardinoglu SciLifeLab Fellow
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Anticancer Agents Med Chem 24 (1) 39-49 [2023-11-14; online 2023-11-14]
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Zhang N, Harbers L, Simonetti M, ..., Bienko M, Crosetto N
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Wang Z, Himanen SV, Haikala HM, ..., Vihervaara A, Barborič M
Nucleic Acids Res. 51 (20) 10970-10991 [2023-11-10; online 2023-10-09]
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Yeaman S, Whiting J, Booker T, ..., Wright S, Zhou L
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NIPMAP: niche-phenotype mapping of multiplex histology data by community ecology.
El Marrahi A, Lipreri F, Kang Z, ..., Alber D, Hausser J
Nat Commun 14 (1) 7182 [2023-11-07; online 2023-11-07]
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Multi-omics characterization of lymphedema-induced adipose tissue from breast cancer patients
Karaman S, Lehti S, Zhang C, ..., Alitalo K, Kivelä R
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Adil Mardinoglu SciLifeLab Fellow
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Enhancers dysfunction in the 3D genome of cancer cells.
Della Chiara G, Jiménez C, Virdi M, Crosetto N, Bienko M
Front Cell Dev Biol 11 (-) 1303862 [2023-11-06; online 2023-11-06]
Magda Bienko SciLifeLab Fellow
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Nat Commun 14 (1) 7039 [2023-11-03; online 2023-11-03]
Anniina Vihervaara SciLifeLab Fellow
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van Hout FAH, Himanen SV, Vihervaara A, Miesen P
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Saeed Shoaie SciLifeLab Fellow
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Tomaszkiewicz M, Sahlin K, Medvedev P, Makova KD
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Radiotracers for Imaging of Fibrosis: Advances during the Last Two Decades and Future Directions.
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Olof Eriksson SciLifeLab Fellow
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Liao X, Ozcan M, Shi M, ..., Mardinoglu A, Zhang C
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Adil Mardinoglu SciLifeLab Fellow
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Phosphate starvation decouples cell differentiation from DNA replication control in the dimorphic bacterium Caulobacter crescentus.
Hallgren J, Koonce K, Felletti M, ..., Turco E, Jonas K
PLoS Genet 19 (11) e1010882 [2023-11-00; online 2023-11-27]
Kristina Jonas SciLifeLab Fellow
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Multi-omics network analysis on samples from sequential biopsies reveals vital role of proliferation arrest for Macrosteatosis related graft failure in rats after liver transplantation.
Liu Z, Wang W, Li X, ..., Mardinoglu A, Zheng S
Genomics 115 (6) 110748 [2023-11-00; online 2023-11-19]
Adil Mardinoglu SciLifeLab Fellow
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Leveraging circulating microbial DNA for early cancer detection.
Kataria R, Shoaie S, Grigoriadis A, Wan JCM
Trends Cancer 9 (11) 879-882 [2023-11-00; online 2023-09-01]
Saeed Shoaie SciLifeLab Fellow
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Host Phylogeny Structures the Gut Bacterial Community Within Galerucella Leaf Beetles.
An Y, Braga MP, Garcia SL, Grudzinska-Sterno M, Hambäck PA
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Semin Immunol 70 (-) 101812 [2023-11-00; online 2023-08-08]
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Mol Ecol Resour 23 (8) 1772-1789 [2023-11-00; online 2023-07-29]
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CRISPR interference screens reveal growth-robustness tradeoffs in Synechocystis sp. PCC 6803 across growth conditions.
Miao R, Jahn M, Shabestary K, Peltier G, Hudson EP
Plant Cell 35 (11) 3937-3956 [2023-10-30; online 2023-07-26]
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Ragaller F, Sjule E, Urem YB, ..., Blom H, Sezgin E
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Erdinc Sezgin SciLifeLab Fellow
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Muntjewerff EM, Josyula VS, Christoffersson G
Bio Protoc 13 (20) e4852 [2023-10-20; online 2023-10-20]
Gustaf Christoffersson SciLifeLab Fellow
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Kim W, Li M, Jin H, ..., Zhang C, Mardinoglu A
iScience 26 (10) 107727 [2023-10-20; online 2023-08-25]
Adil Mardinoglu SciLifeLab Fellow
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Evolution of microRNAs in Amoebozoa and implications for the origin of multicellularity
Edelbroek B, Kjellin J, Biryukova I, ..., Friedländer MR, Söderbom F
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Marc Friedländer SciLifeLab Fellow
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Organic matter lability modifies the vertical structure of methane-related microbial communities in lake sediments.
Rissanen AJ, Jilbert T, Simojoki A, ..., Peura S, Jäntti H
Microbiol Spectr 11 (5) e0195523 [2023-10-17; online 2023-09-12]
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Designing efficient randstrobes for sequence similarity analyses
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Quantification of membrane fluidity in bacteria using TIR-FCS
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Deficiency of the Heterogeneous Nuclear Ribonucleoprotein U locus leads to delayed hindbrain neurogenesis.
Mastropasqua F, Oksanen M, Soldini C, ..., Bölte S, Tammimies K
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Cameron DP, Grosser J, Ladigan S, ..., Hahn SA, Baranello L
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O' Donovan DH, Baker D, Ciotta G, ..., Tang H, Valge-Archer V
Bioorg. Med. Chem. Lett. 96 (-) 129518 [2023-10-12; online 2023-10-12]
SciLifeLab Fellow Yumeng Mao
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Long-Term Effects of Perinatal Exposure to a Glyphosate-Based Herbicide on Melatonin Levels and Oxidative Brain Damage in Adult Male Rats.
Cattani D, Pierozan P, Zamoner A, Brittebo E, Karlsson O
Antioxidants (Basel) 12 (10) - [2023-10-03; online 2023-10-03]
Oskar Karlsson SciLifeLab Fellow
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Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis.
Qu F, Brough SC, Michno W, ..., Pasca AM, Sage J
Nat. Cell Biol. 25 (10) 1506-1519 [2023-10-00; online 2023-10-02]
SciLifeLab Fellow Wojciech Michno
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Modulation of lytic molecules restrain serial killing in γδ T lymphocytes.
Sandoz PA, Kuhnigk K, Szabo EK, ..., Uhlin M, Önfelt B
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Alfjorden A, Brännström IO, Wengström N, ..., Persson D, Burki F
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Fabien Burki SciLifeLab Fellow
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Short tandem repeats bind transcription factors to tune eukaryotic gene expression.
Horton CA, Alexandari AM, Hayes MGB, ..., Kundaje A, Fordyce PM
Science (New York, N.Y.) 381 (6664) eadd1250 [2023-09-22; online 2023-09-22]
Emil Marklund SciLifeLab Fellow
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Imaging of fibrogenesis in the liver by [18F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β.
Wegrzyniak O, Zhang B, Rokka J, ..., Eriksson J, Eriksson O
EJNMMI Radiopharm Chem 8 (1) 23 [2023-09-21; online 2023-09-21]
Olof Eriksson SciLifeLab Fellow
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MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations
Tiemann JKS, Szczuka M, Bouarroudj L, ..., Chavent M, Poulain P
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Lucie Delemotte SciLifeLab Fellow
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Metabolite interactions in the bacterial Calvin cycle and implications for flux regulation.
Sporre E, Karlsen J, Schriever K, ..., Edfors F, Hudson EP
Commun Biol 6 (1) 947 [2023-09-18; online 2023-09-18]
DDLS Fellow Fredrik Edfors Paul Hudson SciLifeLab Fellow
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Systems-level temporal immune-metabolic profile in Crimean-Congo hemorrhagic fever virus infection.
Ambikan AT, Elaldi N, Svensson-Akusjärvi S, ..., Mirazimi A, Neogi U
Proc. Natl. Acad. Sci. U.S.A. 120 (37) e2304722120 [2023-09-12; online 2023-09-05]
Adil Mardinoglu SciLifeLab Fellow
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A novel kleptoplastidic symbiosis revealed in the marine centrohelid Meringosphaera with evidence of genetic integration.
Sørensen MES, Zlatogursky VV, Onuţ-Brännström I, ..., Foster RA, Burki F
Curr. Biol. 33 (17) 3571-3584.e6 [2023-09-11; online 2023-08-02]
Fabien Burki SciLifeLab Fellow
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PI-(3,5)P2-mediated oligomerization of the endosomal sodium/proton exchanger NHE9
Kokane S, Meier PF, Gulati A, ..., Fuster D, Drew D
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Lucie Delemotte SciLifeLab Fellow
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Estrogen receptor activation remodels TEAD1 gene expression to alleviate nonalcoholic fatty liver disease
Sommerauer C, Gallardo-Dodd CJ, Savva C, ..., Williams C, Kutter C
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Claudia Kutter Erdinc Sezgin SciLifeLab Fellow
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Digital assay for rapid electronic quantification of clinical pathogens using DNA nanoballs.
Tayyab M, Barrett D, van Riel G, ..., Javanmard M, Pelechano V
Sci Adv 9 (36) eadi4997 [2023-09-08; online 2023-09-06]
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CCG-1423-derived compounds reduce global RNA synthesis and inhibit transcriptional responses
Prajapati B, Sokolova M, Sidorenko E, ..., Vihervaara A, Vartiainen MK
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Anniina Vihervaara SciLifeLab Fellow
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EGb 761 reduces Ca2+ influx and apoptosis after pentylenetetrazole treatment in a neuroblastoma cell line.
Ovey IS, Ozsimsek A, Velioglu HA, ..., Mardinoglu A, Yulug B
Front. Cell. Neurosci. 17 (-) 1195303 [2023-09-07; online 2023-09-07]
Adil Mardinoglu SciLifeLab Fellow
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Systematic transcriptional analysis of human cell lines for gene expression landscape and tumor representation.
Jin H, Zhang C, Zwahlen M, ..., Uhlén M, Mardinoglu A
Nat Commun 14 (1) 5417 [2023-09-05; online 2023-09-05]
Adil Mardinoglu SciLifeLab Fellow
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Structure-based virtual screening discovers potent and selective adenosine A1 receptor antagonists.
Matricon P, Nguyen AT, Vo DD, ..., May LT, Carlsson J
Eur J Med Chem 257 (-) 115419 [2023-09-05; online 2023-05-01]
Andreas Luttens DDLS Fellow Jens Carlsson SciLifeLab Fellow
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Sex differences in distribution and identity of aromatase gene expressing cells in the young adult rat brain.
Immenschuh J, Thalhammer SB, Sundström-Poromaa I, ..., Dumas S, Comasco E
Biol Sex Differ 14 (1) 54 [2023-09-01; online 2023-09-01]
Erika Comasco SciLifeLab Fellow
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Altered gut microbiota community structure and correlated immune system changes in dibutyl phthalate exposed mice.
Almamoun R, Pierozan P, Manoharan L, Karlsson O
Ecotoxicology and Environmental Safety 262 (-) 115321 [2023-09-01; online 2023-08-05]
Oskar Karlsson SciLifeLab Fellow
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A Two-Step Activation Mechanism Enables Mast Cells to Differentiate their Response between Extracellular and Invasive Enterobacterial Infection
von Beek C, Fahlgren A, Geiser P, ..., Pejler G, Sellin ME
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Mikael Sellin SciLifeLab Fellow
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Vesicular glutamate transporter 2 expression in the ventral tegmental area of outbred male rats following exposure to nicotine and alcohol.
Vrettou M, Thalhammer SB, Svensson AL, ..., Nylander I, Comasco E
Drug Alcohol Depend Rep 8 (-) 100180 [2023-09-00; online 2023-07-13]
Erika Comasco SciLifeLab Fellow
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Real-life data of hypoglycemic events in children and adolescents with type 1 diabetes.
Hill H, Klaar P, Espes D
BMJ Open Diabetes Res Care 11 (5) - [2023-09-00; online 2023-09-23]
Daniel Espes SciLifeLab Fellow
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Pubertal sexual development and endpoints for disrupted spermatogenesis in the model Xenopus tropicalis.
Svanholm S, Roza M, Marini D, ..., Karlsson O, Berg C
Reprod. Toxicol. 120 (-) 108435 [2023-09-00; online 2023-07-01]
Oskar Karlsson SciLifeLab Fellow
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Laboratory evolution of Synechocystis sp. PCC 6803 for phenylpropanoid production.
Kukil K, Englund E, Crang N, Hudson EP, Lindberg P
Metab. Eng. 79 (-) 27-37 [2023-09-00; online 2023-06-29]
Paul Hudson SciLifeLab Fellow
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Infection with COVID-19 is no longer a public emergency: But what about degenerative dementia?
Yulug B, Ayyıldız B, Ayyıldız S, ..., Velioglu HA, Mardinoglu A
J Med Virol 95 (9) e29072 [2023-09-00; online 2023-09-19]
Adil Mardinoglu SciLifeLab Fellow
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Development of microsatellite markers for sister species Linum suffruticosum and Linum tenuifolium in their overlapping ranges.
Olmedo-Vicente E, Désamoré A, Simón-Porcar VI, Slotte T, Arroyo J
Mol. Biol. Rep. 50 (9) 7927-7933 [2023-09-00; online 2023-07-17]
SciLifeLab Fellow Tanja Slotte
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Tissue pleiotropic effect of biotin and prebiotic supplementation in established obesity.
Voland L, Yuan M, Lecoutre S, ..., Soula H, Clément K
Am. J. Physiol. Endocrinol. Metab. - (-) - [2023-08-30; online 2023-08-30]
Adil Mardinoglu SciLifeLab Fellow
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Functional annotation of a divergent genome using sequence and structure-based homology
Svedberg D, Winiger RR, Berg A, ..., Vossbrinck CR, Barandun J
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Jonas Barandun SciLifeLab Fellow
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Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells.
Gallardo-Dodd CJ, Oertlin C, Record J, ..., Ponomarev SA, Westerberg LS
Sci Adv 9 (34) eadg1610 [2023-08-25; online 2023-08-25]
Claudia Kutter SciLifeLab Fellow
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Complex Polyploids: Origins, Genomic Composition, and Role of Introgressed Alleles
Leal JL, Milesi P, Hodková E, ..., Salojärvi J, Lascoux M
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DDLS Fellow Jennifer James Pascal Milesi SciLifeLab Fellow
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Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis
Drexhage LZ, Zhang S, DuPont M, ..., Karaji N, Sattentau QJ
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Erdinc Sezgin SciLifeLab Fellow
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Immobilized Enzymes on Magnetic Beads for Separate Mass Spectrometric Investigation of Human Phase II Metabolite Classes.
Tsiara I, Riemer A, Correia MSP, Rodriguez-Mateos A, Globisch D
Anal. Chem. 95 (33) 12565-12571 [2023-08-22; online 2023-08-08]
Daniel Globisch SciLifeLab Fellow
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Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders
Bon GM, Kraft D, Comasco E, Derntl B, Kaufmann T
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Erika Comasco SciLifeLab Fellow
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Loss of CYP2D6 sensitizes hepatocellular carcinomas and neuroblastomas to talazoparib
Sjöblom T, Zhang X, Rameika N, ..., Heim M, Globisch D
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Daniel Globisch SciLifeLab Fellow
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The acute effect of different NAD+ precursors included in the combined metabolic activators.
Li X, Yang H, Jin H, ..., Borén J, Mardinoglu A
Free Radic. Biol. Med. 205 (-) 77-89 [2023-08-20; online 2023-06-02]
Adil Mardinoglu SciLifeLab Fellow
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Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S
Nat Commun 14 (1) 5019 [2023-08-18; online 2023-08-18]
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Pathogenic entero- and salivatypes harbour changes in microbiome virulence and antimicrobial resistance genes with increasing chronic liver disease severity
Lee S, Arefaine B, Begum N, ..., Shoaie S, Patel VC
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Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Separation of transcriptional repressor and activator functions in Drosophila HDAC3.
Tang M, Regadas I, Belikov S, ..., Bienko M, Mannervik M
Development 150 (15) - [2023-08-01; online 2023-08-02]
Magda Bienko SciLifeLab Fellow
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Longitudinal metabolomics analysis reveals the acute effect of cysteine and NAC included in the combined metabolic activators.
Yang H, Li X, Jin H, ..., Borén J, Mardinoglu A
Free Radic. Biol. Med. 204 (-) 347-358 [2023-08-01; online 2023-05-26]
Adil Mardinoglu SciLifeLab Fellow
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Umbilical cord-derived mesenchymal stromal cells preserve endogenous insulin production in type 1 diabetes: a Phase I/II randomised double-blind placebo-controlled trial.
Carlsson PO, Espes D, Sisay S, ..., Smith CIE, Svahn MG
Diabetologia 66 (8) 1431-1441 [2023-08-00; online 2023-05-24]
Daniel Espes SciLifeLab Fellow
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Historical RNA expression profiles from the extinct Tasmanian tiger.
Mármol-Sánchez E, Fromm B, Oskolkov N, ..., Dalén L, Friedländer MR
Genome Res 33 (8) 1299-1316 [2023-08-00; online 2023-07-18]
Marc Friedländer SciLifeLab Fellow
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Oxidative, Genotoxic and Cytotoxic Damage Potential of Novel Borenium and Borinium Compounds
Oguzkan SB, Turkez H, Ugras HI, Tatar A, Mardinoglu A
Inorganics 11 (8) 324 [2023-07-31; online 2023-07-31]
Adil Mardinoglu SciLifeLab Fellow
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Phosphate starvation decouples cell differentiation from DNA replication control in the dimorphic bacterium Caulobacter crescentus
Hallgren J, Koonce K, Felletti M, ..., Turco E, Jonas K
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Kristina Jonas SciLifeLab Fellow
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Naltrexone blocks alcohol-induced effects on kappa-opioid receptors in the plasma membrane.
Terenius L, Oasa S, Sezgin E, ..., Martin-Fardon R, Vukojevic V
Res Sq - (-) - [2023-07-21; online 2023-07-21]
Erdinc Sezgin SciLifeLab Fellow
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Coevolution-driven method for efficiently simulating conformational changes in proteins reveals molecular details of ligand effects in the β2AR receptor
Mitrovic D, Chen Y, Marciniak A, Delemotte L
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Lucie Delemotte SciLifeLab Fellow
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Development of an Effective Functional Lipid Anchor for Membranes (FLAME) for the Bioorthogonal Modification of the Lipid Bilayer of Mesenchymal Stromal Cells.
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SciLifeLab Fellow Simon Elsässer
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Erika Comasco SciLifeLab Fellow
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Adil Mardinoglu SciLifeLab Fellow
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Erik Benson SciLifeLab Fellow
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Adil Mardinoglu SciLifeLab Fellow
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Mikael Sellin SciLifeLab Fellow
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Transl Psychiatry 13 (1) 124 [2023-04-14; online 2023-04-14]
Erika Comasco SciLifeLab Fellow
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Mohammed M, Dziedziech A, Sekar V, ..., Vega-Rodriguez J, Ankarklev J
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Marc Friedländer SciLifeLab Fellow
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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The exosome degrades chromatin-associated RNAs genome-wide and maintains chromatin homeostasis
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Free energy landscapes of KcsA inactivation
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CRISPR-Cas9-mediated genome engineering exaggerates genomic deletion at 10q23.31 including the PTEN gene locus mimicking cancer profiles
Geng K, Merino LG, Veiga RG, ..., Brinkman EK, Kutter C
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Claudia Kutter SciLifeLab Fellow
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Mucosal and Plasma Metabolomes in New-onset Paediatric Inflammatory Bowel Disease: Correlations with Disease Characteristics and Plasma Inflammation Protein Markers.
Nyström N, Prast-Nielsen S, Correia M, ..., Schuppe-Koistinen I, Halfvarson J
J Crohns Colitis 17 (3) 418-432 [2023-04-03; online 2022-10-12]
Daniel Globisch SciLifeLab Fellow
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IL-1 receptor-associated kinase-3 acts as an immune checkpoint in myeloid cells to limit cancer immunotherapy.
Tunalı G, Rúbies Bedós M, Nagarajan D, ..., Papakyriacou I, Mao Y
J. Clin. Invest. 133 (7) - [2023-04-03; online 2023-04-03]
SciLifeLab Fellow Yumeng Mao
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Epithelial and microbial determinants of colonic drug distribution.
Hammar R, Sellin ME, Artursson P
Eur J Pharm Sci 183 (-) 106389 [2023-04-01; online 2023-01-20]
Mikael Sellin SciLifeLab Fellow
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Voices of the new generation: normalizing career choices outside academia.
Sezgin E
Nat. Rev. Mol. Cell Biol. 24 (4) 237 [2023-04-00; online 2023-01-20]
Erdinc Sezgin SciLifeLab Fellow
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The liver kinase B1 supports mammary epithelial morphogenesis by inhibiting critical factors that mediate epithelial-mesenchymal transition.
Tzavlaki K, Ohata Y, Morén A, ..., Heldin CH, Moustakas A
J. Cell. Physiol. 238 (4) 790-812 [2023-04-00; online 2023-02-15]
Mikael Sellin SciLifeLab Fellow
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Extending fluorescence anisotropy to large complexes using reversibly switchable proteins.
Volpato A, Ollech D, Alvelid J, ..., Ingaramo M, Testa I
Nat. Biotechnol. 41 (4) 552-559 [2023-04-00; online 2022-10-10]
Ilaria Testa SciLifeLab Fellow
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Dynamic antagonism between key repressive pathways maintains the placental epigenome.
Weigert R, Hetzel S, Bailly N, ..., Smith ZD, Meissner A
Nat. Cell Biol. 25 (4) 579-591 [2023-04-00; online 2023-04-06]
SciLifeLab Fellow Simon Elsässer
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Deep mutational scan of a drug efflux pump reveals its structure-function landscape.
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Nat. Chem. Biol. 19 (4) 440-450 [2023-04-00; online 2022-11-28]
Jonas Barandun SciLifeLab Fellow
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Author Correction: PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing.
Cikes D, Elsayad K, Sezgin E, ..., Banka S, Penninger JM
Nat Metab 5 (4) 711 [2023-04-00; online 2023-04-07]
Erdinc Sezgin SciLifeLab Fellow
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A frame-shift mutation in COMTD1 is associated with impaired pheomelanin pigmentation in chicken.
Bi H, Tranell J, Harper DC, ..., Globisch D, Andersson L
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Daniel Globisch SciLifeLab Fellow
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Linking prokaryotic genome size variation to metabolic potential and environment.
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ISME Commun 3 (1) 25 [2023-03-27; online 2023-03-27]
Sarahi Garcia SciLifeLab Fellow
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Dual stop codon suppression in mammalian cells with genomically integrated genetic code expansion machinery
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SciLifeLab Fellow Simon Elsässer
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Correlative Chemical Imaging and Spatial Chemometrics Delineate Alzheimer Plaque Heterogeneity at High Spatial Resolution.
Wehrli PM, Ge J, Michno W, ..., Blennow K, Hanrieder J
JACS Au 3 (3) 762-774 [2023-03-27; online 2023-03-07]
SciLifeLab Fellow Wojciech Michno
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Modulation of Pore Opening of Eukaryotic Sodium Channels by π-helices in S6
Choudhury K, Delemotte L
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Lucie Delemotte SciLifeLab Fellow
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Costunolide and Parthenolide Ameliorate MPP+ Induced Apoptosis in the Cellular Parkinson's Disease Model.
Arslan ME, Türkez H, Sevim Y, ..., Öner S, Mardinoğlu A
Cells 12 (7) - [2023-03-24; online 2023-03-24]
Adil Mardinoglu SciLifeLab Fellow
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standard-GEM: standardization of open-source genome-scale metabolic models
Anton M, Almaas E, Benfeitas R, ..., Zeidan AA, Kerkhoven EJ
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Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release
Wang Z, Himanen SV, Haikala HM, ..., Vihervaara A, Barborič M
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Anniina Vihervaara SciLifeLab Fellow
DOI Crossref
The association of the RSC remodeler complex with chromatin depends on prefoldin-like Bud27 and determines nucleosome positioning and polyadenylation sites usage in Saccharomyces cerevisiae
Cuevas-Bermúdez A, Martínez-Fernández V, Garrido-Godino AI, ..., Pelechano V, Navarro F
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SciLifeLab Fellow
PubMed DOI Crossref
Transcript Isoform Diversity of Ampliconic Genes on the Y Chromosome of Great Apes.
Tomaszkiewicz M, Sahlin K, Medvedev P, Makova KD
bioRxiv - (-) - [2023-03-18; online 2023-03-18]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
TASL Practice Guidance on the Clinical Assessment and Management of Patients with Nonalcoholic Fatty Liver Disease.
Yilmaz Y, Zeybel M, Adali G, ..., Kaymakoglu S, Gunsar F
Hepatol Forum 4 (Suppl 1) 1-32 [2023-03-15; online 2023-03-15]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
An intracellular hydrophobic nexus is critical for slow deactivation in hERG channels
Stevens-Sostre WA, Flores-Aldama L, Bustos D, ..., Delemotte L, Robertson GA
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Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
A Mitosome With Distinct Metabolism in the Uncultured Protist Parasite Paramikrocytos canceri (Rhizaria, Ascetosporea).
Onuț-Brännström I, Stairs CW, Campos KIA, ..., Bass D, Burki F
Genome Biol Evol 15 (3) - [2023-03-03; online 2023-02-16]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Structural basis of mitochondrial membrane bending by the I-II-III2-IV2 supercomplex.
Mühleip A, Flygaard RK, Baradaran R, ..., Sharma V, Amunts A
Nature 615 (7954) 934-938 [2023-03-00; online 2023-03-22]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Palidis: fast discovery of novel insertion sequences.
Carr VR, Pissis SP, Mullany P, ..., Gomez-Cabrero D, Moyes DL
Microb Genom 9 (3) - [2023-03-00; online 2023-03-11]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
PET Imaging of Neutrophil Elastase with 11C-GW457427 in Acute Respiratory Distress Syndrome in Pigs.
Puuvuori E, Chiodaroli E, Estrada S, ..., Eriksson O, Antoni G
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 64 (3) 423-429 [2023-03-00; online 2022-09-15]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing.
Cikes D, Elsayad K, Sezgin E, ..., Banka S, Penninger JM
Nat Metab 5 (3) 495-515 [2023-03-00; online 2023-03-20]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
In silico tissue generation and power analysis for spatial omics.
Baker EAG, Schapiro D, Dumitrascu B, Vickovic S, Regev A
Nat. Methods 20 (3) 424-431 [2023-03-00; online 2023-03-02]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
An open-source microscopy framework for simultaneous control of image acquisition, reconstruction, and analysis.
Casas Moreno X, Silva MM, Roos J, ..., Norlin N, Testa I
HardwareX 13 (-) e00400 [2023-03-00; online 2023-02-06]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling.
Altea-Manzano P, Doglioni G, Liu Y, ..., Malanchi I, Fendt SM
Nat Cancer 4 (3) 344-364 [2023-03-00; online 2023-02-02]
SciLifeLab Fellow
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Magnetoresponsive fluorescent core-shell nanoclusters for biomedical applications.
Saladino GM, Kakadiya R, Ansari SR, Teleki A, Toprak MS
Nanoscale Adv 5 (5) 1323-1330 [2023-02-28; online 2023-01-31]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells during Salmonella gut infection
Gül E, Fattinger SA, Nguyen BD, ..., Sellin ME, Hardt WD
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Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Reconstructing clonal tree for phylo-phenotypic characterization of cancer using single-cell transcriptomics.
Jun SH, Toosi H, Mold J, ..., Roth A, Lagergren J
Nat Commun 14 (1) 982 [2023-02-22; online 2023-02-22]
Camilla Engblom SciLifeLab Fellow
DOI Crossref
Modulation of lytic molecules restrain serial killing in γδ T lymphocytes
Onfelt B, Sandoz P, Kuhnigk K, ..., Malmberg KJ, Uhlin M
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Patrick Sandoz SciLifeLab Fellow
PubMed DOI Crossref
Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events.
Allen G, Weiss B, Panasenko OO, ..., Pelechano V, Collart MA
Genome Biol. 24 (1) 30 [2023-02-20; online 2023-02-20]
SciLifeLab Fellow
PubMed DOI Crossref
Systematic diet composition swap in a mouse genome-scale metabolic model reveals determinants of obesogenic diet metabolism in liver cancer.
Clasen F, Nunes PM, Bidkhori G, ..., Shoaie S, Anastasiou D
iScience 26 (2) 106040 [2023-02-17; online 2023-01-24]
Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Macrocyclic Pyrrolizidine Alkaloids and Silphiperfolanol Angelate Esters from Solanecio mannii
Umereweneza D, Atilaw Y, Peintner S, ..., Gogoll A, Erdelyi M
Eur. J. Org. Chem. 26 (8) - [2023-02-17; online 2023-01-30]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation.
Li B, Zeis P, Zhang Y, ..., Steinmetz LM, Pelechano V
Nat Commun 14 (1) 910 [2023-02-17; online 2023-02-17]
SciLifeLab Fellow
PubMed DOI Crossref
Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection.
Mikaeloff F, Gelpi M, Benfeitas R, ..., Nielsen SD, Neogi U
Elife 12 (-) - [2023-02-16; online 2023-02-16]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
CRISPR interference screens reveal tradeoffs between growth rate and robustness in Synechocystis sp. PCC 6803 across trophic conditions
Miao R, Jahn M, Shabestary K, Hudson EP
- - (-) - [2023-02-13; online 2023-02-13]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
An α-π transition in S6 shapes the conformational cycle of the bacterial sodium channel NavAb.
Choudhury K, Howard RJ, Delemotte L
J. Gen. Physiol. 155 (2) - [2023-02-06; online 2022-12-14]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
PRO-IP-seq Tracks Molecular Modifications of Engaged Pol II Complexes at Nucleotide Resolution.
Vihervaara A, Versluis P, Lis JT
bioRxiv - (-) - [2023-02-04; online 2023-02-04]
Anniina Vihervaara SciLifeLab Fellow
DOI Crossref
Hybridization Mediated Range Expansion and Climate Change Resilience in Two Keystone Tree Species of Boreal Forests
Karunarathne P, Zhou Q, Lascoux M, Milesi P
- - (-) - [2023-02-03; online 2023-02-03]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
[18F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44.
Cheung P, Amin MA, Zhang B, ..., Odell LR, Eriksson O
Pharmaceutics 15 (2) - [2023-02-02; online 2023-02-02]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Far Red-Shifted CdTe Quantum Dots for Multicolour Stimulated Emission Depletion Nanoscopy.
Alvelid J, Bucci A, Testa I
Chemphyschem 24 (3) e202200698 [2023-02-01; online 2022-11-09]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases.
Turkez H, Altay O, Yildirim S, ..., Uhlén M, Mardinoglu A
Life Sci 314 (-) 121325 [2023-02-01; online 2022-12-26]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
DOI Crossref
PIP2 binding at the voltage sensor domain facilitates KCNQ1 VSD activation and gating
Pipatpolkai T, Mitrovic D, Cui J, Delemotte L
Biophysical Journal 122 (3) 29a [2023-02-00; online 2023-02-00]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
High-content analysis shows synergistic effects of low perfluorooctanoic acid (PFOS) and perfluorooctane sulfonic acid (PFOA) mixture concentrations on human breast epithelial cell carcinogenesis.
Pierozan P, Kosnik M, Karlsson O
Environ Int 172 (-) 107746 [2023-02-00; online 2023-01-12]
Oskar Karlsson SciLifeLab Fellow
DOI Crossref
Diversity and enrichment of breeding material for resilience in European forests
Olsson S, Dauphin B, Jorge V, ..., Bastien C, Alia R
Forest Ecology and Management 530 (-) 120748 [2023-02-00; online 2023-02-00]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties
Ragaller F, Andronico L, Sykora J, ..., Vattulainen I, Sezgin E
Biophysical Journal 122 (3) 224a [2023-02-00; online 2023-02-00]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells.
Hsu J, Fatuzzo N, Weng N, ..., Nasca C, Khosla C
J Biol Chem 299 (2) 102848 [2023-02-00; online 2022-12-30]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
A GC-centered view of 3D genome organization.
Bouwman BA, Crosetto N, Bienko M
Curr. Opin. Genet. Dev. 78 (-) 102020 [2023-02-00; online 2023-01-05]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Editorial: Effects of hormonal contraceptives on the brain.
Pletzer B, Comasco E, Hidalgo-Lopez E, Lacreuse A, Derntl B
Front Endocrinol (Lausanne) 14 (-) 1129203 [2023-01-31; online 2023-01-31]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: a randomised, double-blinded, placebo-controlled phase-II trial.
Yulug B, Altay O, Li X, ..., Uhlén M, Mardinoglu A
Transl Neurodegener 12 (1) 4 [2023-01-26; online 2023-01-26]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase.
Battisti UM, Gao C, Akladios F, ..., Mardinoglu A, Grøtli M
Nutrients 15 (3) - [2023-01-22; online 2023-01-22]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Metabolic modelling of the human gut microbiome in type 2 diabetes patients in response to metformin treatment.
Ezzamouri B, Rosario D, Bidkhori G, ..., Uhlen M, Shoaie S
NPJ Syst Biol Appl 9 (1) 2 [2023-01-21; online 2023-01-21]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Simulation Reveals the Chameleonic Behavior of Macrocycles.
Sethio D, Poongavanam V, Xiong R, ..., Lindh R, Kihlberg J
J Chem Inf Model 63 (1) 138-146 [2023-01-09; online 2022-12-23]
Ruisheng Xiong SciLifeLab Fellow
DOI Crossref
Resilience of genetic diversity in forest trees over the Quaternary
Milesi P, Kastally C, Dauphin B, ..., Lascoux M, Pyhäjärvi T
- - (-) - [2023-01-06; online 2023-01-06]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
Drug repositioning for immunotherapy in breast cancer using single-cell analysis
Mohammadi E, Jin H, Zhang C, ..., Mardinoglu A, Sekhavati MH
- - (-) - [2023-01-05; online 2023-01-05]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Author response: Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection
Mikaeloff F, Gelpi M, Benfeitas R, ..., Nielsen SD, Neogi U
- - (-) - [2023-01-04; online 2023-01-04]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase.
Battisti UM, Gao C, Nilsson O, ..., Mardinoglu A, Grøtli M
Chembiochem 24 (1) e202200339 [2023-01-03; online 2022-11-09]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Cover Feature: Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase (ChemBioChem 1/2023)
Battisti UM, Gao C, Nilsson O, ..., Mardinoglu A, Grøtli M
Chembiochem 24 (1) - [2023-01-03; online 2022-12-14]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with 11C-NES.
Antoni G, Lubberink M, Sörensen J, ..., Skorup P, Lipcsey M
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 64 (1) 145-148 [2023-01-00; online 2022-06-09]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Divergent selection predating the Last Glacial Maximum mainly acted on macro-phenotypes in Norway spruce.
Tiret M, Olsson L, Grahn T, ..., Lundqvist SO, García-Gil MR
Evol Appl 16 (1) 163-172 [2023-01-00; online 2022-12-20]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
The Role of Willpower in Major Depressive Disorder: An fMRI Study
Yulug B, Uygur B, Sayman D, ..., Velioglu HA, Mardinoglu A
- - (-) - [2023-00-00; online 2023-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Impaired Immuno-Metabolic Homeostasis and Microenvironmental Influence on Neuropsychiatric Risk in Treated HIV Infection
Mikaeloff F, Gelpi M, Escós A, ..., Nielsen SD, Neogi U
- - (-) - [2023-00-00; online 2023-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Genome-Wide Annotation of the Human Protein-Coding Genes Using Co-Expression Clustering
Bueno Álvez M, Karlsson M, Shi M, ..., Fagerberg L, Lindskog C
- - (-) - [2023-00-00; online 2023-00-00]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
DOI Crossref
Genetically Incorporated Non-Canonical Amino Acids
Methods in molecular biology (Clifton, N.J.) - (-) - [2023-00-00; online 2023-00-00]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
Engineered aldolases catalyzing stereoselective aldol reactions between aryl-substituted ketones and aldehydes
Cornelius EC, Bartl M, Persson LJ, ..., Dobritzsch D, Widersten M
Catal. Sci. Technol. 13 (17) 4978-4987 [2023-00-00; online 2023-00-00]
Ruisheng Xiong SciLifeLab Fellow
DOI Crossref
Ckap4 is Identified as a Therapeutic Target for the Treatment of Kidney Fibrosis
Shi M, Xu P, Kim W, ..., Mardinoglu A, Zhang C
- - (-) - [2023-00-00; online 2023-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Characterization of an <i>in vitro</i> Steatosis Model for Modelling the Activated <i>de novo</i> Lipogenesis in MAFLD Patients
Kim W, Li M, Jin H, ..., Zhang C, Mardinoglu A
- - (-) - [2023-00-00; online 2023-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Brain sex classification in the limbic system as female-specific phenotype for depression
Bon GM, Kraft D, Comasco E, Derntl B, Kaufmann T
Neuroscience Applied 2 (-) 103357 [2023-00-00; online 2023-00-00]
Erika Comasco SciLifeLab Fellow

Year 2022

PubMed DOI Crossref
Lipoic Acid Conjugated Boron Hybrids Enhance Wound Healing and Antimicrobial Processes.
Türkez H, Yıldırım ÖÇ, Öner S, ..., Yapça ÖE, Mardinoğlu A
Pharmaceutics 15 (1) - [2022-12-31; online 2022-12-31]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences.
Velikyan I, Bossart M, Haack T, ..., Wagner M, Eriksson O
Pharmaceuticals (Basel, Switzerland) 16 (1) - [2022-12-31; online 2022-12-31]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Structure of plant Photosystem I in a native assembly state
Naschberger A, Fadeeva M, Klaiman D, ..., Nelson N, Amunts A
- - (-) - [2022-12-28; online 2022-12-28]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
mapquik: Efficient low-divergence mapping of long reads in minimizer space
Ekim B, Sahlin K, Medvedev P, Berger B, Chikhi R
- - (-) - [2022-12-23; online 2022-12-23]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease.
Leng H, Zhang H, Li L, ..., Simon AK, Horwood NJ
Nat Commun 13 (1) 7868 [2022-12-22; online 2022-12-22]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Evolutionary trade-offs associated with copy number variations in resistance alleles in Culex pipiens mosquitoes.
Milesi P, Claret JL, Unal S, Weill M, Labbé P
Parasit Vectors 15 (1) 484 [2022-12-22; online 2022-12-22]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Strobealign: flexible seed size enables ultra-fast and accurate read alignment.
Sahlin K
Genome Biol. 23 (1) 260 [2022-12-15; online 2022-12-15]
Kristoffer Sahlin SciLifeLab Fellow
DOI Crossref
Enhanced Sampling Methods for Molecular Dynamics Simulations [Article v1.0]
Hénin J, Lelièvre T, Shirts MR, Valsson O, Delemotte L
LiveCoMS 4 (1) 1583 [2022-12-14; online 2022-12-14]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
B cell expansion hinders the stroma-epithelium regenerative cross talk during mucosal healing.
Frede A, Czarnewski P, Monasterio G, ..., Das S, Villablanca EJ
Immunity 55 (12) 2336-2351.e12 [2022-12-13; online 2022-12-02]
Camilla Engblom SciLifeLab Fellow
DOI Crossref
dgram2dmap: Extraction, visualisation and formatting of distance constraints from AlphaFold distograms
Wallner B, Amunts A, Naschberger A, Nystedt B, Mirabello C
- - (-) - [2022-12-12; online 2022-12-12]
Alexey Amunts SciLifeLab Fellow
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Manipulation of topoisomerase expression inhibits cell division but not growth and reveals a distinctive promoter structure in Synechocystis.
Behle A, Dietsch M, Goldschmidt L, ..., Axmann IM, Machné R
Nucleic Acids Res. 50 (22) 12790-12808 [2022-12-09; online 2022-12-20]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Structure of the mitoribosomal small subunit with streptomycin reveals Fe-S clusters and physiological molecules.
Itoh Y, Singh V, Khawaja A, ..., Rorbach J, Amunts A
Elife 11 (-) - [2022-12-08; online 2022-12-08]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Safety in Multi-Assembly via Paths Appearing in All Path Covers of a DAG.
Caceres M, Mumey B, Husic E, ..., Sahlin K, Tomescu AI
IEEE/ACM Trans Comput Biol Bioinform 19 (6) 3673-3684 [2022-12-08; online 2022-12-08]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Convolutional Neural Networks as Summary Statistics for Approximate Bayesian Computation.
AKesson M, Singh P, Wrede F, Hellander A
IEEE/ACM Trans Comput Biol Bioinform 19 (6) 3353-3365 [2022-12-08; online 2022-12-08]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
In Vitro Transcriptome Analysis of Cobalt Boride Nanoparticles on Human Pulmonary Alveolar Cells.
Arslan ME, Tatar A, Yıldırım ÖÇ, ..., Mardinoğlu A, Türkez H
Materials (Basel) 15 (23) - [2022-12-06; online 2022-12-06]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Development of l-Dopa-containing diketopiperazines as blood-brain barrier shuttle.
Cornacchia C, Marinelli L, Di Rienzo A, ..., Di Stefano A, Cacciatore I
Eur J Med Chem 243 (-) 114746 [2022-12-05; online 2022-09-08]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
High-efficiency transfection of Acanthamoeba castellanii using a cationic polymer
Moreno AB, Ek V, Eriksson J, Sellin ME, Guy L
- - (-) - [2022-12-01; online 2022-12-01]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Teasing apart the joint effect of demography and natural selection in the birth of a contact zone.
Li L, Milesi P, Tiret M, ..., Wu HX, Lascoux M
New Phytol. 236 (5) 1976-1987 [2022-12-00; online 2022-09-30]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Systematic comparison of modeling fidelity levels and parameter inference settings applied to negative feedback gene regulation.
Coulier A, Singh P, Sturrock M, Hellander A
PLoS Comput Biol 18 (12) e1010683 [2022-12-00; online 2022-12-15]
Prashant Singh SciLifeLab Fellow
DOI Crossref
Inorganic nanoparticles for oral drug delivery: opportunities, barriers, and future perspectives
Asad S, Jacobsen AC, Teleki A
Current Opinion in Chemical Engineering 38 (-) 100869 [2022-12-00; online 2022-12-00]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
How broad is the selfing syndrome? Insights from convergent evolution of gene expression across species and tissues in the Capsella genus.
Zhang Z, Kryvokhyzha D, Orsucci M, ..., Milesi P, Lascoux M
New Phytol. 236 (6) 2344-2357 [2022-12-00; online 2022-09-30]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Grey matter morphology in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator.
Kaltsouni E, Dubol M, Wikström J, ..., Sundström-Poromaa I, Comasco E
Eur Neuropsychopharmacol 65 (-) 35-43 [2022-12-00; online 2022-11-04]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Genomic Profiling Identifies Putative Pathogenic Alterations in NSCLC Brain Metastases.
Nicoś M, Harbers L, Patrucco E, ..., Ambrogio C, Crosetto N
JTO Clin Res Rep 3 (12) 100435 [2022-12-00; online 2022-11-11]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
ADP-ribosyltransferases, an update on function and nomenclature.
Lüscher B, Ahel I, Altmeyer M, ..., Zaja R, Ziegler M
FEBS J. 289 (23) 7399-7410 [2022-12-00; online 2021-09-13]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
Gasdermin D is the only Gasdermin that provides non-redundant protection against acute Salmonella gut infection
Fattinger SA, Maurer L, Geiser P, ..., Sellin ME, Hardt WD
- - (-) - [2022-11-25; online 2022-11-25]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Editorial: Application of systems biology in molecular characterization and diagnosis of cancer, Volume II.
Wei Y, Zhang C, Mardinoglu A, Zhang P
Front Mol Biosci 9 (-) 1089463 [2022-11-25; online 2022-11-25]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Spatial transcriptomics of T and B cell receptors uncovers lymphocyte clonal dynamics in human tissue
Engblom C, Thrane K, Lin Q, ..., Lundeberg J, Frisén J
- - (-) - [2022-11-24; online 2022-11-24]
Camilla Engblom SciLifeLab Fellow
DOI Crossref
METTL17 is an Fe-S cluster checkpoint for mitochondrial translation
Ast T, Itoh Y, Sadre S, ..., Amunts A, Mootha VK
- - (-) - [2022-11-24; online 2022-11-24]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Breast cancer spheroids can model phenotypic heterogeneity of cancer cells to evaluate targeted therapies.
mahmoud l, cougnoux a, bekiari c, ..., gsell l, hausser j
- - (-) - [2022-11-22; online 2022-11-22]
Jean Hausser SciLifeLab Fellow
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Toxicity of Glycyl-l-Prolyl-l-Glutamate Pseudotripeptides: Cytotoxic, Oxidative, Genotoxic, and Embryotoxic Perspectives.
Turkez H, Ozdemir Tozlu O, Tatar A, ..., Di Stefano A, Mardinoglu A
J Toxicol 2022 (-) 3775194 [2022-11-19; online 2022-11-19]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Drug repositioning for immunotherapy in breast cancer using single-cell and spatial transcriptomics analysis
Mohammadi E, Jin H, Zhang C, ..., Mardinoglu A, Sekhavati MH
- - (-) - [2022-11-18; online 2022-11-18]
Adil Mardinoglu SciLifeLab Fellow
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CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.
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A Multiparametric and High-Throughput Platform for Host-Virus Binding Screens
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Target-enriched nanopore sequencing and de novo assembly reveals co-occurrences of complex on-target genomic rearrangements induced by CRISPR-Cas9 in human cells.
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Claudia Kutter SciLifeLab Fellow
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Algal photosystem I dimer and high-resolution model of PSI-plastocyanin complex.
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Reconstructing the transport cycle in the sugar porter superfamily using coevolution-powered machine learning
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Lucie Delemotte SciLifeLab Fellow
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Tumoroscope: a probabilistic model for mapping cancer clones in tumor tissues
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Olof Eriksson SciLifeLab Fellow
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Magda Bienko SciLifeLab Fellow
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Alexey Amunts SciLifeLab Fellow
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Assessment of the neuroprotective potential of d-cycloserine and l-serine in aluminum chloride-induced experimental models of Alzheimer's disease: In vivo and in vitro studies.
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Paul Hudson SciLifeLab Fellow
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Alexey Amunts SciLifeLab Fellow
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Mitochondrial ATP synthase of trypanosomes reveals the mechanism of oligomerization and its evolution
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Biochim Biophys Acta Bioenerg 1863 (-) 148628 [2022-09-00; online 2022-09-00]
Alexey Amunts SciLifeLab Fellow
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Enhanced cytotoxicity of a novel family of ATPase inhibitors in colorectal cancer cells with high NAT2 activity.
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Biochem. Pharmacol. 203 (-) 115184 [2022-09-00; online 2022-07-22]
Daniel Globisch SciLifeLab Fellow
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Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties.
Ragaller F, Andronico L, Sykora J, ..., Vattulainen I, Sezgin E
Open Biol 12 (9) 220175 [2022-09-00; online 2022-09-14]
Erdinc Sezgin SciLifeLab Fellow
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Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning.
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EBioMedicine 83 (-) 104214 [2022-09-00; online 2022-08-18]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors.
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Microbiol Spectr 10 (4) e0175521 [2022-08-31; online 2022-07-25]
Daniel Globisch SciLifeLab Fellow
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Nucleic Acids Res. 50 (15) 8491-8511 [2022-08-26; online 2022-07-30]
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Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity.
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Cell Syst 13 (8) 665-681.e4 [2022-08-17; online 2022-07-08]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Zeitotox: Toxicology and the Rhythms of Life.
Xiao L, Antczak P, Rüegg J, Behrendt L
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Lars Behrendt SciLifeLab Fellow
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Microbial functional genes are driven by gradients in sediment stoichiometry, oxygen, and salinity across the Baltic benthic ecosystem.
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Microbiome 10 (1) 126 [2022-08-15; online 2022-08-15]
Sarahi Garcia SciLifeLab Fellow
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agoTRIBE detects miRNA-target interactions transcriptome-wide in single cells
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Marc Friedländer SciLifeLab Fellow
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A Universal Language for Finding Mass Spectrometry Data Patterns
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Daniel Globisch SciLifeLab Fellow
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Ameliorative Effects by Hexagonal Boron Nitride Nanoparticles against Beta Amyloid Induced Neurotoxicity.
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Nanomaterials (Basel) 12 (15) - [2022-08-05; online 2022-08-05]
Adil Mardinoglu SciLifeLab Fellow
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Adult Exposure to Di-N-Butyl Phthalate (DBP) Induces Persistent Effects on Testicular Cell Markers and Testosterone Biosynthesis in Mice.
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Oskar Karlsson SciLifeLab Fellow
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Genome-wide single cell annotation of the human protein-coding genes
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Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
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What can cold-induced transcriptomes of Arctic Brassicaceae tell us about the evolution of cold tolerance?
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Mol. Ecol. 31 (16) 4271-4285 [2022-08-00; online 2022-07-15]
SciLifeLab Fellow Tanja Slotte
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Photophysiological response of Symbiodiniaceae single cells to temperature stress.
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ISME J 16 (8) 2060-2064 [2022-08-00; online 2022-04-26]
Fabien Burki Lars Behrendt SciLifeLab Fellow
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Mutation accumulation opposes polymorphism: supergenes and the curious case of balanced lethals.
Berdan EL, Blanckaert A, Butlin RK, ..., Slotte T, Wielstra B
Philos. Trans. R. Soc. Lond., B, Biol. Sci. 377 (1856) 20210199 [2022-08-00; online 2022-06-13]
SciLifeLab Fellow Tanja Slotte
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BMP4 and Gremlin 1 regulate hepatic cell senescence during clinical progression of NAFLD/NASH.
Baboota RK, Rawshani A, Bonnet L, ..., Blüher M, Smith U
Nat Metab 4 (8) 1007-1021 [2022-08-00; online 2022-08-22]
Adil Mardinoglu SciLifeLab Fellow
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Author Correction: Spatiotemporal dissection of the cell cycle with single-cell proteogenomics.
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Nature 608 (7924) E32 [2022-08-00; online 2022-08-06]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Boron Compounds Exhibit Protective Effects against Aluminum-Induced Neurotoxicity and Genotoxicity: In Vitro and In Vivo Study.
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Adil Mardinoglu SciLifeLab Fellow
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Boron Nitride Nanoparticles Loaded with a Boron-Based Hybrid as a Promising Drug Carrier System for Alzheimer's Disease Treatment.
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Sanja Vickovic SciLifeLab Fellow
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Robust and integrative Bayesian neural networks for likelihood-free parameter inference
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Prashant Singh SciLifeLab Fellow
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Miniaturized and multiplexed high-content screening of drug and immune sensitivity in a multichambered microwell chip.
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Cell Rep Methods 2 (7) 100256 [2022-07-18; online 2022-07-18]
Patrick Sandoz SciLifeLab Fellow
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A broad, exposome-type evaluation of xenobiotic phase II biotransformation in human biofluids by LC-MS/MS
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Daniel Globisch SciLifeLab Fellow
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Genome-scale metabolic modelling of the human gut microbiome reveals changes in the glyoxylate and dicarboxylate metabolism in metabolic disorders.
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iScience 25 (7) 104513 [2022-07-15; online 2022-06-02]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain.
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Nat Commun 13 (1) 4087 [2022-07-15; online 2022-07-15]
Lucie Delemotte SciLifeLab Fellow
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Reductive evolution in the structure of the microsporidian proteasome
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Jonas Barandun SciLifeLab Fellow
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An atlas of endogenous DNA double-strand breaks arising during human neural cell fate determination.
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Sci Data 9 (1) 400 [2022-07-12; online 2022-07-12]
Magda Bienko SciLifeLab Fellow
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Single particle profiler for measuring content and properties of nano-sized bioparticles
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Daniel Fürth Erdinc Sezgin SciLifeLab Fellow
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Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation.
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Alexey Amunts SciLifeLab Fellow
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Lucie Delemotte SciLifeLab Fellow
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T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles.
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Differential grey matter structure in women with premenstrual dysphoric disorder: evidence from brain morphometry and data-driven classification.
Dubol M, Stiernman L, Wikström J, ..., Bixo M, Comasco E
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Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection
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Adil Mardinoglu SciLifeLab Fellow
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Markov State Modelling Reveals Heterogeneous Drug-Inhibition Mechanism of Calmodulin
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Lucie Delemotte SciLifeLab Fellow
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FOXO1 and FOXO3 Cooperatively Regulate Innate Lymphoid Cell Development.
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Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties
Ragaller F, Andronico L, Sykora J, ..., Vattulainen I, Sezgin E
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Erdinc Sezgin SciLifeLab Fellow
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Subtype-specific responses of hKv7.4 and hKv7.5 channels to polyunsaturated fatty acids reveal an unconventional modulatory site and mechanism.
Frampton DJA, Choudhury K, Nikesjö J, Delemotte L, Liin SI
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Lucie Delemotte SciLifeLab Fellow
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Cornille A, Tiret M, Salcedo A, ..., Wright SI, Lascoux M
AoB Plants 14 (3) plac011 [2022-06-00; online 2022-04-02]
Pascal Milesi SciLifeLab Fellow
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TGFβ selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial-mesenchymal transition.
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Mol Oncol 16 (12) 2330-2354 [2022-06-00; online 2022-04-10]
Mikael Sellin SciLifeLab Fellow
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Rapid in situ identification of biological specimens via DNA amplicon sequencing using miniaturized laboratory equipment.
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Nat Protoc 17 (6) 1415-1443 [2022-06-00; online 2022-04-11]
Kristoffer Sahlin SciLifeLab Fellow
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Potato genomes pave the way to crop improvement.
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Nature 606 (7914) 472-473 [2022-06-00; online 2022-06-09]
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Polycomb repressive complex 2 shields naïve human pluripotent cells from trophectoderm differentiation.
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OPUSeq simplifies detection of low-frequency DNA variants and uncovers fragmentase-associated artifacts.
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NAR Genomics and Bioinformatics 4 (2) lqac048 [2022-06-00; online 2022-06-27]
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Heparin‐Derived Theranostic Nanoprobes Overcome the Blood–Brain Barrier and Target Glioma in Murine Model
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Olof Eriksson SciLifeLab Fellow
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Machine Learning Analysis Reveals Biomarkers for the Detection of Neurological Diseases.
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Live single cell imaging assays in glass microwells produced by laser-induced deep etching.
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Patrick Sandoz SciLifeLab Fellow
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Genomic analyses of the Linum distyly supergene reveal convergent evolution at the molecular level
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SciLifeLab Fellow Tanja Slotte
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Inhibition of Respiratory Syncytial Virus Infection by Small Non-Coding RNA Fragments.
Pålsson SA, Sekar V, Kutter C, Friedländer MR, Spetz AL
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Claudia Kutter Marc Friedländer SciLifeLab Fellow
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Multi-omics analyses reveal multimodal Fusobacterium DNA damage perturbations in colorectal cancer
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Saeed Shoaie SciLifeLab Fellow
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Simultaneous visualization of flow fields and oxygen concentrations to unravel transport and metabolic processes in biological systems.
Ahmerkamp S, Jalaluddin FM, Cui Y, ..., Koren K, Behrendt L
Cell Rep Methods 2 (5) 100216 [2022-05-23; online 2022-05-23]
Lars Behrendt SciLifeLab Fellow
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A survey of mapping algorithms in the long-reads era
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Kristoffer Sahlin SciLifeLab Fellow
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Interplay between VSD, pore and membrane lipids in electromechanical coupling in HCN channels
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Lucie Delemotte SciLifeLab Fellow
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Dangerous RNA links pave the way to glioblastoma.
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Mol. Cell 82 (10) 1783-1785 [2022-05-19; online 2022-05-21]
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Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms.
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Alexandra Teleki SciLifeLab Fellow
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Patatin-like phospholipase CapV in Escherichia coli - morphological and physiological effects of one amino acid substitution.
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Kristina Jonas SciLifeLab Fellow
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Author response: Subtype-specific responses of hKv7.4 and hKv7.5 channels to polyunsaturated fatty acids reveal an unconventional modulatory site and mechanism
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Lucie Delemotte SciLifeLab Fellow
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Maternal prenatal depressive symptoms and toddler behavior: an umbilical cord blood epigenome-wide association study.
Kallak TK, Fransson E, Bränn E, ..., Lyle R, Skalkidou A
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Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation
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Tissue ischemia induces mobilization of pro-angiogenic neutrophils from the spleen
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Prashant Singh SciLifeLab Fellow
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Glucagonlike Peptide-1 Receptor Imaging in Individuals with Type 2 Diabetes.
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Direct Observation of Na,K‐ATPase Oligomers in The Plasma Membrane of Living Cells by FRET‐FCS
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Mol. Microbiol. 117 (5) 1156-1172 [2022-05-00; online 2022-04-12]
Mikael Sellin SciLifeLab Fellow
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Understanding immune signaling using advanced imaging techniques.
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Biochem. Soc. Trans. 50 (2) 853-866 [2022-04-29; online 2022-03-29]
Erdinc Sezgin SciLifeLab Fellow
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Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress.
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Science (New York, N.Y.) 376 (6592) 476-483 [2022-04-29; online 2022-04-28]
SciLifeLab Fellow Simon Elsässer
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Recent Progress and Future Direction for the Application of Multiomics Data in Clinical Liver Transplantation.
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Adil Mardinoglu SciLifeLab Fellow
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Metabolic modelling of the human gut microbiome in type 2 diabetes patients in response to metformin treatment
Ezzamouri B, Rosario D, Bidkori G, ..., Uhlen M, Shoaie S
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Saeed Shoaie SciLifeLab Fellow
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A DNA molecular printer capable of programmable positioning and patterning in two dimensions.
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Sci Robot 7 (65) eabn5459 [2022-04-20; online 2022-04-20]
Erik Benson SciLifeLab Fellow
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The Role of Bio‐based Excipients in the Formulation of Lipophilic Nutraceuticals
Teleki A, Tsekou C, Connolly A
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Alexandra Teleki SciLifeLab Fellow
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Oskar Karlsson SciLifeLab Fellow
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Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase.
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Eur J Med Chem 234 (-) 114270 [2022-04-15; online 2022-03-08]
Adil Mardinoglu SciLifeLab Fellow
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Irritable bowel syndrome and microbiome; Switching from conventional diagnosis and therapies to personalized interventions.
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Grey matter correlates of affective and somatic symptoms of premenstrual dysphoric disorder.
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Sci Rep 12 (1) 5996 [2022-04-09; online 2022-04-09]
Erika Comasco SciLifeLab Fellow
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PET-CT imaging of pulmonary inflammation using [68Ga]Ga-DOTA-TATE.
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Olof Eriksson SciLifeLab Fellow
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Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
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Single-cell transcriptomics to define Plasmodium falciparum stage-transition in the mosquito midgut
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Marc Friedländer SciLifeLab Fellow
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Uniting diversity to create a more inclusive academic environment.
Delemotte L, Garcia SL, Rodríguez-Gijón A, Sezgin E, Vihervaara A
J. Cell. Sci. 135 (7) - [2022-04-01; online 2022-04-12]
Anniina Vihervaara Erdinc Sezgin Lucie Delemotte Sarahi Garcia SciLifeLab Fellow
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Giant plasma membrane vesicles to study plasma membrane structure and dynamics.
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Erdinc Sezgin SciLifeLab Fellow
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Exploration of ultrasound-mediated microbubble-cell membrane interactions using novel protein-loaded microbubbles and their role in immunomodulation
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Erdinc Sezgin SciLifeLab Fellow
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Prediction of drug candidates for clear cell renal cell carcinoma using a systems biology-based drug repositioning approach.
Li X, Shong K, Kim W, ..., Zhang C, Mardinoglu A
EBioMedicine 78 (-) 103963 [2022-04-00; online 2022-03-25]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Multiomics Analysis Reveals the Impact of Microbiota on Host Metabolism in Hepatic Steatosis.
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Adv Sci (Weinh) 9 (11) e2104373 [2022-04-00; online 2022-02-07]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
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Long-term SARS-CoV-2-specific and cross-reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology.
Laurén I, Havervall S, Ng H, ..., Thålin C, Mangsbo S
Immun Inflamm Dis 10 (4) e595 [2022-04-00; online 2022-03-30]
Gustaf Christoffersson SciLifeLab Fellow
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Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target.
Smati S, Polizzi A, Fougerat A, ..., Gourdy P, Guillou H
Gut 71 (4) 807-821 [2022-04-00; online 2021-04-26]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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IgE cross-linking induces activation of human and mouse mast cell progenitors.
Méndez-Enríquez E, Salomonsson M, Eriksson J, ..., Sellin ME, Hallgren J
J. Allergy Clin. Immunol. 149 (4) 1458-1463 [2022-04-00; online 2021-09-04]
Mikael Sellin SciLifeLab Fellow
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Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging.
Mishra K, Fuenzalida-Werner JP, Pennacchietti F, ..., Ntziachristos V, Stiel AC
Nat. Biotechnol. 40 (4) 598-605 [2022-04-00; online 2021-11-29]
Ilaria Testa SciLifeLab Fellow
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Acute sleep loss alters circulating fibroblast growth factor 21 levels in humans: A randomised crossover trial.
Mateus Brandão LE, Espes D, Westholm JO, ..., Benedict C, Cedernaes J
J Sleep Res 31 (2) e13472 [2022-04-00; online 2021-09-02]
Daniel Espes SciLifeLab Fellow
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Taxonomic and functional diversity of aquatic heterotrophs is sustained by dissolved organic matter chemodiversity
Garcia SL, Nuy JK, Mehrshad M, ..., Hawkes J, Bertilsson S
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Sarahi Garcia SciLifeLab Fellow
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Molecular Genetics and Cytotoxic Responses to Titanium Diboride and Zinc Borate Nanoparticles on Cultured Human Primary Alveolar Epithelial Cells.
Türkez H, Arslan ME, Tatar A, ..., Tatar A, Mardinoglu A
Materials (Basel) 15 (7) - [2022-03-22; online 2022-03-22]
Adil Mardinoglu SciLifeLab Fellow
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A Gene Co-Expression Network-Based Drug Repositioning Approach Identifies Candidates for Treatment of Hepatocellular Carcinoma.
Yuan M, Shong K, Li X, ..., Zhang C, Mardinoglu A
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Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Quantifying RNA synthesis at rate-limiting steps of transcription using nascent RNA-sequencing data.
Rabenius A, Chandrakumaran S, Sistonen L, Vihervaara A
STAR Protoc 3 (1) 101036 [2022-03-18; online 2022-01-05]
Anniina Vihervaara SciLifeLab Fellow
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Data mining of Saccharomyces cerevisiae mutants engineered for increased tolerance towards inhibitors in lignocellulosic hydrolysates.
Cámara E, Olsson L, Zrimec J, ..., Geijer C, Nygård Y
Biotechnol Adv 57 (-) 107947 [2022-03-18; online 2022-03-18]
Aleksej Zelezniak SciLifeLab Fellow
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Navarro C, Martin M, Elsässer S
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SciLifeLab Fellow Simon Elsässer
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Metabolite interactions in the bacterial Calvin cycle and implications for flux regulation
Sporre E, Karlsen J, Schriever K, ..., Edfors F, Hudson EP
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DDLS Fellow Fredrik Edfors Paul Hudson SciLifeLab Fellow
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Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events
Allen G, Weiss B, Panasenko O, ..., Pelechano V, Collart MA
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Norway spruce postglacial recolonization of Fennoscandia.
Nota K, Klaminder J, Milesi P, ..., Suyama Y, Parducci L
Nat Commun 13 (1) 1333 [2022-03-14; online 2022-03-14]
Pascal Milesi SciLifeLab Fellow
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A broad, exposome-type evaluation of xenobiotic phase II biotransformation in human biofluids by LC-MS/MS
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Daniel Globisch SciLifeLab Fellow
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Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43.
Garcia Morato J, Hans F, von Zweydorf F, ..., Neumann M, Kahle PJ
Nat Commun 13 (1) 1223 [2022-03-09; online 2022-03-09]
SciLifeLab Fellow Simon Elsässer
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Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan
Correia-Melo C, Kamrad S, Messner CB, ..., Papp B, Ralser M
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Aleksej Zelezniak SciLifeLab Fellow
DOI Crossref
Four tumor micro-environmental niches explain a continuum of inter-patient variation in the macroscopic cellular composition of breast tumors
Marrahi AE, Lipreri F, Alber D, Hausser J
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Jean Hausser SciLifeLab Fellow
DOI Crossref
Critical role of PCYT2 in muscle health and aging
Cikes D, Elsayad K, Sezgin E, ..., Banka S, Penninger JM
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Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Inducible CRISPR/Cas9 allows for multiplexed and rapidly segregated single target genome editing in Synechocystis sp. PCC 6803
Cengic I, Cañadas IC, Minton NP, Hudson EP
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Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
The SWI/SNF subunit BRG1 affects alternative splicing by changing RNA binding factor interactions with nascent RNA.
Gañez-Zapater A, Mackowiak SD, Guo Y, ..., Visa N, Östlund Farrants AK
Mol. Genet. Genomics 297 (2) 463-484 [2022-03-00; online 2022-02-20]
DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
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On the origin of TSAR: morphology, diversity and phylogeny of Telonemia.
Tikhonenkov DV, Jamy M, Borodina AS, ..., Burki F, Karpov SA
Open Biol 12 (3) 210325 [2022-03-00; online 2022-03-16]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Epigenetics in the Anthropocene: an interview with Oskar Karlsson.
Karlsson O
Epigenomics 14 (6) 315-318 [2022-03-00; online 2022-02-23]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Correction to: Toxicogenomics directory of chemically exposed human hepatocytes.
Grinberg M, Stöber RM, Edlund K, ..., Rahnenführer J, Hengstler JG
Arch. Toxicol. 96 (3) 945-946 [2022-03-00; online 2022-02-01]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
ADAR1- and ADAR2-mediated regulation of maturation and targeting of miR-376b to modulate GABA neurotransmitter catabolism.
Widmark A, Sagredo EA, Karlström V, ..., Daniel C, Öhman M
J Biol Chem 298 (3) 101682 [2022-03-00; online 2022-02-03]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction.
Begnini F, Geschwindner S, Johansson P, ..., Schiesser S, Kihlberg J
J Med Chem 65 (4) 3473-3517 [2022-02-24; online 2022-02-02]
Andreas Luttens DDLS Fellow Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
White matter microstructure and volume correlates of premenstrual dysphoric disorder.
Gu X, Dubol M, Stiernman L, ..., Sundström-Poromaa I, Comasco E
J Psychiatry Neurosci 47 (1) E67-E76 [2022-02-23; online 2022-02-23]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses.
Luttens A, Gullberg H, Abdurakhmanov E, ..., Danielson UH, Carlsson J
Journal of the American Chemical Society 144 (7) 2905-2920 [2022-02-23; online 2022-02-10]
Andreas Luttens DDLS Fellow Jens Carlsson SciLifeLab Fellow
DOI Crossref
Thermodynamic limitations of metabolic strategies for PHB production from formate and fructose in Cupriavidus necator
Janasch M, Crang N, Bruch M, ..., Jahn M, Hudson EP
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Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Identification of electroporation sites in the complex lipid organization of the plasma membrane.
Rems L, Tang X, Zhao F, ..., Testa I, Delemotte L
Elife 11 (-) - [2022-02-23; online 2022-02-23]
Ilaria Testa Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Stratification of the Gut Microbiota Composition Landscape across the Alzheimer's Disease Continuum in a Turkish Cohort.
Yıldırım S, Nalbantoğlu ÖU, Bayraktar A, ..., Köseoğlu E, Hanoğlu L
mSystems 7 (1) e0000422 [2022-02-22; online 2022-02-08]
Adil Mardinoglu SciLifeLab Fellow
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Genome-wide mapping of G-quadruplex structures with CUT&Tag.
Lyu J, Shao R, Kwong Yung PY, Elsässer SJ
Nucleic Acids Res. 50 (3) e13 [2022-02-22; online 2021-11-19]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Tumorigenic activity of alternative per- and polyfluoroalkyl substances (PFAS): Mechanistic in vitro studies.
Pierozan P, Cattani D, Karlsson O
Sci. Total Environ. 808 (-) 151945 [2022-02-20; online 2021-11-27]
Oskar Karlsson SciLifeLab Fellow
DOI Crossref
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning
Zhang C, Shi M, Kim W, ..., Boren J, Mardinoglu A
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Machine learning analysis reveals biomarkers for the detection of neurodegenerative diseases
Lam S, Arif M, Song X, Uhlen M, Mardinoglu A
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium.
Vickovic S, Schapiro D, Carlberg K, ..., Regev A, Ståhl PL
Commun Biol 5 (1) 129 [2022-02-11; online 2022-02-11]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
The spatial transcriptomic landscape of the healing mouse intestine following damage.
Parigi SM, Larsson L, Das S, ..., Lundeberg J, Villablanca EJ
Nat Commun 13 (1) 828 [2022-02-11; online 2022-02-11]
Camilla Engblom SciLifeLab Fellow
PubMed DOI Crossref
Prevalence and correlates of current suicidal ideation in women with premenstrual dysphoric disorder.
Wikman A, Sacher J, Bixo M, ..., Comasco E, Sundström Poromaa I
BMC Womens Health 22 (1) 35 [2022-02-11; online 2022-02-11]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Simultaneous visualization of DNA loci in single cells by combinatorial multi-color iFISH.
Mota A, Schweitzer M, Wernersson E, Crosetto N, Bienko M
Sci Data 9 (1) 47 [2022-02-10; online 2022-02-10]
Magda Bienko SciLifeLab Fellow
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SM-Omics is an automated platform for high-throughput spatial multi-omics.
Vickovic S, Lötstedt B, Klughammer J, ..., Rozenblatt-Rosen O, Regev A
Nat Commun 13 (1) 795 [2022-02-10; online 2022-02-10]
Sanja Vickovic SciLifeLab Fellow
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Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae.
Nadeem A, Berg A, Pace H, ..., Uhlin BE, Wai SN
Elife 11 (-) - [2022-02-08; online 2022-02-08]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Expression Profiles of Estrogen-Regulated MicroRNAs in Cancer Cells.
Archer A, Kutter C, Williams C
Methods in molecular biology (Clifton, N.J.) 2418 (-) 313-343 [2022-02-05; online 2022-02-05]
Claudia Kutter SciLifeLab Fellow
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ZFP207 sustains pluripotency by coordinating OCT4 stability, alternative splicing and RNA export.
Malla S, Prasad Bhattarai D, Groza P, ..., Kutter C, Aguilo F
EMBO Rep. 23 (3) e53191 [2022-02-03; online 2022-01-17]
Claudia Kutter SciLifeLab Fellow
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Author response: Identification of electroporation sites in the complex lipid organization of the plasma membrane
Rems L, Tang X, Zhao F, ..., Testa I, Delemotte L
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Ilaria Testa Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Structural basis of streptomycin off-target binding to human mitoribosome
Itoh Y, Khawaja A, Singh V, ..., Rorbach J, Amunts A
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Alexey Amunts SciLifeLab Fellow
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Possible Functional Roles of Patellamides in the Ascidian-Prochloron Symbiosis.
Baur P, Kühl M, Comba P, Behrendt L
Mar Drugs 20 (2) - [2022-02-02; online 2022-02-02]
Lars Behrendt SciLifeLab Fellow
DOI Crossref
Deconwolf enables high-performance deconvolution of widefield fluorescence microscopy images
Wernersson E, Gelali E, Girelli G, ..., Crosetto N, Bienko M
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Magda Bienko SciLifeLab Fellow
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ExSTED microscopy reveals contrasting functions of dopamine and somatostatin CSF-c neurons along the lamprey central canal.
Jalalvand E, Alvelid J, Coceano G, ..., Grillner S, Testa I
Elife 11 (-) - [2022-02-01; online 2022-02-01]
Ilaria Testa SciLifeLab Fellow
DOI Crossref
Towards effective beta-cell replacement through understanding and targeting of the autoreactive immune response during onset of type 1 diabetes
Christoffersson G
Journal of Immunology and Regenerative Medicine 15 (-) 100057 [2022-02-00; online 2022-02-00]
Gustaf Christoffersson SciLifeLab Fellow
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Structural amyloid plaque polymorphism is associated with distinct lipid accumulations revealed by trapped ion mobility mass spectrometry imaging.
Michno W, Wehrli PM, Koutarapu S, ..., Hopf C, Hanrieder J
J. Neurochem. 160 (4) 482-498 [2022-02-00; online 2021-12-26]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Rifaximin-α reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised controlled trial.
Patel VC, Lee S, McPhail MJW, ..., Shoaie S, Shawcross DL
J Hepatol 76 (2) 332-342 [2022-02-00; online 2021-09-24]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
RNA gradients: Shapers of 3D genome architecture.
Bouwman BAM, Crosetto N, Bienko M
Curr Opin Cell Biol 74 (-) 7-12 [2022-02-00; online 2022-01-05]
Magda Bienko SciLifeLab Fellow
DOI Crossref
Molecular modeling investigation of proton coupling in XylE
Alleva C, Drew D, Delemotte L
Biophysical Journal 121 (3) 468a [2022-02-00; online 2022-02-00]
Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Details of G-protein coupled receptor activation via data-driven molecular modeling
Delemotte L, Fleetwood O, Chen Y, Pérez Conesa S
Biophysical Journal 121 (3) 285a [2022-02-00; online 2022-02-00]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Sequence specificity in DNA binding is mainly governed by association.
Marklund E, Mao G, Yuan J, ..., Deindl S, Elf J
Science (New York, N.Y.) 375 (6579) 442-445 [2022-01-28; online 2022-01-27]
Emil Marklund SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Role of Cellular Metabolism during Candida-Host Interactions.
Pellon A, Begum N, Sadeghi Nasab SD, ..., Shoaie S, Moyes DL
Pathogens 11 (2) - [2022-01-28; online 2022-01-28]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Irisin-A Pancreatic Islet Hormone.
Norman D, Drott CJ, Carlsson PO, Espes D
Biomedicines 10 (2) - [2022-01-25; online 2022-01-25]
Daniel Espes SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide annotation of protein-coding genes in pig.
Karlsson M, Sjöstedt E, Oksvold P, ..., Luo Y, Uhlen M
BMC Biol. 20 (1) 25 [2022-01-25; online 2022-01-25]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Biogenic methane cycling is controlled by microbial cohorts
Mondav R, Martin G, Peura S, Garcia SL
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Sarahi Garcia Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development.
Cornes E, Bourdon L, Singh M, ..., Li B, Cecere G
Dev. Cell 57 (2) 180-196.e7 [2022-01-24; online 2021-12-17]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
BioRssay: an R package for analyses of bioassays and probit graphs.
Karunarathne P, Pocquet N, Labbé P, Milesi P
Parasit Vectors 15 (1) 35 [2022-01-24; online 2022-01-24]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
Author response: Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae
Nadeem A, Berg A, Pace H, ..., Uhlin BE, Wai SN
- - (-) - [2022-01-19; online 2022-01-19]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
An Image-Analysis-Based Method for the Prediction of Recombinant Protein Fiber Tensile Strength.
Bäcklund FG, Schmuck B, Miranda GHB, ..., Rydén J, Rising A
Materials (Basel) 15 (3) - [2022-01-18; online 2022-01-18]
Gisele Miranda SciLifeLab Fellow
DOI Crossref
Teasing apart the joint effect of demography and natural selection in the birth of a contact zone
Li L, Milesi P, Tiret M, ..., Wu H, Lascoux M
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Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
CCT3-LINC00326 axis regulates hepatocarcinogenic lipid metabolism.
Søndergaard JN, Sommerauer C, Atanasoai I, ..., Barragan I, Kutter C
Gut 71 (10) 2081-2092 [2022-01-12; online 2022-01-12]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo.
Hanke L, Das H, Sheward DJ, ..., Murrell B, McInerney GM
Nat Commun 13 (1) 155 [2022-01-10; online 2022-01-10]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
MirGeneDB 2.1: toward a complete sampling of all major animal phyla.
Fromm B, Høye E, Domanska D, ..., Friedländer MR, Peterson KJ
Nucleic Acids Res. 50 (D1) D204-D210 [2022-01-07; online 2021-12-02]
DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
DOI Crossref
Heparin-derived theranostic nanoprobes overcome the blood brain barrier and target glioma in murine model
Samanta S, Joncour VL, Wegrzyniak O, ..., Cabral H, Oommen OP
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Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Genomic Signatures of Sexual Selection on Pollen-Expressed Genes in Arabis alpina.
Gutiérrez-Valencia J, Fracassetti M, Horvath R, ..., Kolář F, Slotte T
Mol. Biol. Evol. 39 (1) - [2022-01-07; online 2021-12-09]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Controls for Phylogeny and Robust Analysis in Pareto Task Inference.
Adler M, Tendler A, Hausser J, ..., Mayo A, Alon U
Mol. Biol. Evol. 39 (1) - [2022-01-07; online 2021-10-12]
Jean Hausser SciLifeLab Fellow
PubMed DOI Crossref
TRP channels: branching out into the fungal kingdom.
Hellmich UA, Delemotte L
Structure 30 (1) 2-4 [2022-01-06; online 2022-01-08]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
A Genomic Perspective Across Earth's Microbiomes Reveals That Genome Size in Archaea and Bacteria Is Linked to Ecosystem Type and Trophic Strategy.
Rodríguez-Gijón A, Nuy JK, Mehrshad M, ..., Woyke T, Garcia SL
Front Microbiol 12 (-) 761869 [2022-01-05; online 2022-01-05]
Sarahi Garcia SciLifeLab Fellow
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Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist.
Bossart M, Wagner M, Elvert R, ..., Nitsche A, Konkar A
Cell Metab. 34 (1) 59-74.e10 [2022-01-04; online 2021-12-20]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
An open state of a voltage-gated sodium channel involving a π-helix and conserved pore-facing asparagine.
Choudhury K, Kasimova MA, McComas S, Howard RJ, Delemotte L
Biophys. J. 121 (1) 11-22 [2022-01-04; online 2021-12-08]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
The revolution evolution.
Amunts A
Nat Plants 8 (1) 14-17 [2022-01-00; online 2021-12-18]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Revisiting sORFs: overcoming challenges to identify and characterize functional microproteins.
Schlesinger D, Elsässer SJ
FEBS J. 289 (1) 53-74 [2022-01-00; online 2021-02-24]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Putative regulation of macrophage-mediated inflammation by catestatin.
Muntjewerff EM, Christoffersson G, Mahata SK, van den Bogaart G
Trends Immunol. 43 (1) 41-50 [2022-01-00; online 2021-11-27]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Publisher Correction: A practical guide to large-scale docking.
Bender BJ, Gahbauer S, Luttens A, ..., Irwin JJ, Shoichet BK
Nat Protoc 17 (1) 177 [2022-01-00; online 2021-12-11]
Andreas Luttens DDLS Fellow Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Improvement of the performance of anticancer peptides using a drug repositioning pipeline.
Mohammadi E, Tahmoorespur M, Benfeitas R, ..., Mardinoglu A, Sekhavati MH
Biotechnol J 17 (1) e2100417 [2022-01-00; online 2021-11-14]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Identification of dynamic mass-action biochemical reaction networks using sparse Bayesian methods.
Jiang R, Singh P, Wrede F, Hellander A, Petzold L
PLoS Comput Biol 18 (1) e1009830 [2022-01-00; online 2022-01-31]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Distinct transcription kinetics of pluripotent cell states.
Shao R, Kumar B, Lidschreiber K, ..., Cramer P, Elsässer SJ
Mol Syst Biol 18 (1) e10407 [2022-01-00; online 2022-01-13]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Cell type-specific analysis by single-cell profiling identifies a stable mammalian tRNA-mRNA interface and increased translation efficiency in neurons.
Gao W, Gallardo-Dodd CJ, Kutter C
Genome Res 32 (1) 97-110 [2022-01-00; online 2021-12-02]
Claudia Kutter SciLifeLab Fellow
DOI Crossref
Transient Colonising Microbes Promote Gut Dysbiosis and Disease Pathology
Lee S, Meslier V, Bidkhori G, ..., Uhlen M, Shoaie S
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Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
STED and RESOLFT Fluorescent Nanoscopy
Bodén A, Pennacchietti F, Testa I
- - (-) 201-232 [2022-00-00; online 2023-01-03]
Ilaria Testa SciLifeLab Fellow
DOI Crossref
Diffusion Measurements at the Nanoscale with STED-FCS
Schneider F, Sezgin E
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Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Development of L-Dopa-Containing Diketopiperazines as Blood-Brain Barrier Shuttle
Cornacchia C, Marinelli L, Di Rienzo A, ..., Di Stefano A, Cacciatore I
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Adil Mardinoglu SciLifeLab Fellow

Year 2021

PubMed DOI Crossref
Endogenous Levels of Gamma Amino-Butyric Acid Are Correlated to Glutamic-Acid Decarboxylase Antibody Levels in Type 1 Diabetes.
Hill H, Elksnis A, Lundkvist P, ..., Carlsson PO, Espes D
Biomedicines 10 (1) - [2021-12-31; online 2021-12-31]
Daniel Espes SciLifeLab Fellow
PubMed DOI Crossref
Therapeutic Potential of Ferulic Acid in Alzheimer's Disease.
Turkez H, Arslan ME, Barboza JN, ..., de Sousa DP, Mardinoğlu A
Curr Drug Deliv 19 (8) 860-873 [2021-12-30; online 2021-12-30]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases
Amunts A, Gahura O, Muhleip A, ..., Slapničková M, Zikova A
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Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Potential of [11C]UCB-J as a PET tracer for islets of Langerhans.
Puuvuori E, Rokka J, Carlsson PO, ..., Eriksson J, Eriksson O
Sci Rep 11 (1) 24466 [2021-12-28; online 2021-12-28]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Regional Brain Analysis of Modified Amino Acids and Dipeptides during the Sleep/Wake Cycle.
Vallianatou T, Bèchet NB, Correia MSP, Lundgaard I, Globisch D
Metabolites 12 (1) - [2021-12-27; online 2021-12-27]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Allosteric Effect of Nanobody Binding on Ligand-Specific Active States of the β2 Adrenergic Receptor.
Chen Y, Fleetwood O, Pérez-Conesa S, Delemotte L
J Chem Inf Model 61 (12) 6024-6037 [2021-12-27; online 2021-11-15]
Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Author response: ExSTED microscopy reveals contrasting functions of dopamine and somatostatin CSF-c neurons along the lamprey central canal
Jalalvand E, Alvelid J, Coceano G, ..., Grillner S, Testa I
- - (-) - [2021-12-20; online 2021-12-20]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Phylogenomic Insights into the Origin of Primary Plastids.
Irisarri I, Strassert JFH, Burki F
Syst. Biol. 71 (1) 105-120 [2021-12-16; online 2021-05-15]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Accurate spliced alignment of long RNA sequencing reads.
Sahlin K, Mäkinen V
Bioinformatics 37 (24) 4643-4651 [2021-12-11; online 2021-07-25]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Selection on Accessible Chromatin Regions in Capsella grandiflora.
Horvath R, Josephs EB, Pesquet E, ..., Scofield D, Slotte T
Mol. Biol. Evol. 38 (12) 5563-5575 [2021-12-09; online 2021-09-10]
SciLifeLab Fellow Tanja Slotte
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Systems Biology Approaches to Decipher the Underlying Molecular Mechanisms of Glioblastoma Multiforme.
Kaynar A, Altay O, Li X, ..., Shoaie S, Mardinoglu A
Int J Mol Sci 22 (24) 13213 [2021-12-08; online 2021-12-08]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes.
Carravilla P, Dasgupta A, Zhurgenbayeva G, ..., Sezgin E, Eggeling C
Biophys Rep (N Y) 1 (2) None [2021-12-08; online 2021-12-08]
Erdinc Sezgin SciLifeLab Fellow
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FRET-FISH probes chromatin compaction at individual genomic loci in single cells
Mota A, Wernersson E, Li-Wang X, ..., Crosetto N, Bienko M
- - (-) - [2021-12-08; online 2021-12-08]
Magda Bienko SciLifeLab Fellow
DOI Crossref
Proactive autoscaling for edge computing systems with kubernetes
Ju L, Singh P, Toor S
- - (-) - [2021-12-06; online 2022-02-07]
Prashant Singh SciLifeLab Fellow
DOI Crossref
What can cold-induced transcriptomes of Arctic Brassicaceae tell us about the evolution of cold tolerance?
Birkeland S, Slotte T, Brysting AK, ..., Brochmann C, Nowak MD
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SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
The Current State of Beta-Cell-Mass PET Imaging for Diabetes Research and Therapies.
Cheung P, Eriksson O
Biomedicines 9 (12) - [2021-12-03; online 2021-12-03]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire.
Fattinger SA, Sellin ME, Hardt WD
Curr Opin Microbiol 64 (-) 9-18 [2021-12-00; online 2021-09-06]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Next generation plasma proteome profiling of COVID-19 patients with mild to moderate symptoms.
Zhong W, Altay O, Arif M, ..., Uhlen M, Fagerberg L
EBioMedicine 74 (-) 103723 [2021-12-00; online 2021-11-27]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
In vitro transcriptome response to propolis in differentiated SH-SY5Y neurons.
Turkez H, Arslan ME, Yilmaz A, ..., Abd El-Aty AM, Mardinoglu A
J Food Biochem 45 (12) e13990 [2021-12-00; online 2021-11-03]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Differential regulation of oxidative stress, microbiota-derived, and energy metabolites in the mouse brain during sleep.
Vallianatou T, Lin W, Bèchet NB, ..., Lundgaard I, Globisch D
J. Cereb. Blood Flow Metab. 41 (12) 3324-3338 [2021-12-00; online 2021-07-22]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Comprehensive analysis of chemical and biological problems associated with browning agents used in aquatic studies
Scharnweber K, Peura S, Attermeyer K, ..., Tranvik LJ, Székely AJ
Limnol Oceanogr Methods 19 (12) 818-835 [2021-12-00; online 2021-10-28]
Sarahi Garcia Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Author Correction: RecA finds homologous DNA by reduced dimensionality search.
Wiktor J, Gynnå AH, Leroy P, ..., Testa I, Elf J
Nature 600 (7887) E11 [2021-12-00; online 2021-11-14]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Interleukin-35 Prevents Development of Autoimmune Diabetes Possibly by Maintaining the Phenotype of Regulatory B Cells.
Luo Z, Lundin S, Mejia-Cordova M, ..., Sandler S, Singh K
Int J Mol Sci 22 (23) - [2021-11-30; online 2021-11-30]
Daniel Espes SciLifeLab Fellow
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Editorial: Methanotrophs: Diversity, Environmental Relevance and Applications.
Cervantes FJ, Garcia SL, Peura S, Balagurusamy N
Front Microbiol 12 (-) 796861 [2021-11-29; online 2021-11-29]
Sarahi Garcia Sari Peura SciLifeLab Fellow
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HSFs drive stress type-specific transcription of genes and enhancers
Himanen SV, Puustinen MC, Da Silva AJ, Vihervaara A, Sistonen L
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Anniina Vihervaara SciLifeLab Fellow
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High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue
Crosetto N, Zhang N, Harbers L, ..., Marchiò C, Bienko M
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Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Fragment-based design of selective GPCR ligands guided by free energy simulations.
Matricon P, Vo DD, Gao ZG, ..., Jacobson KA, Carlsson J
Chem. Commun. (Camb.) 57 (92) 12305-12308 [2021-11-19; online 2021-11-19]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
A network-based approach reveals the dysregulated transcriptional regulation in non-alcoholic fatty liver disease.
Yang H, Arif M, Yuan M, ..., Zhang C, Mardinoglu A
iScience 24 (11) 103222 [2021-11-19; online 2021-10-05]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Single cell genomics reveals plastid-lacking Picozoa are close relatives of red algae.
Schön ME, Zlatogursky VV, Singh RP, ..., Wideman JG, Burki F
Nat Commun 12 (1) 6651 [2021-11-17; online 2021-11-17]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Boron-based hybrids as novel scaffolds for the development of drugs with neuroprotective properties.
Cacciatore I, Turkez H, Di Rienzo A, ..., Mardinoglu A, Di Stefano A
RSC Med Chem 12 (11) 1944-1949 [2021-11-17; online 2021-08-13]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Using High-Sensitivity Lipidomics To Assess Microscale Heterogeneity in Oceanic Sinking Particles and Single Phytoplankton Cells.
Hunter JE, Fredricks HF, Behrendt L, ..., Stocker R, Van Mooy BAS
Environ. Sci. Technol. 55 (22) 15456-15465 [2021-11-16; online 2021-11-01]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
MapToCleave: High-throughput profiling of microRNA biogenesis in living cells.
Kang W, Fromm B, Houben AJ, ..., Biryukova I, Friedländer MR
Cell Reports 37 (7) 110015 [2021-11-16; online 2021-11-18]
Marc Friedländer SciLifeLab Fellow
DOI Crossref
Influence of the extracellular domain size on the dynamic behavior of membrane proteins
Gurdap CO, Wedemann L, Sych T, Sezgin E
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Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Engineered Human Induced Pluripotent Cells Enable Genetic Code Expansion in Brain Organoids.
van Husen LS, Katsori AM, Meineke B, ..., Schedin-Weiss S, Elsässer SJ
Chembiochem 22 (22) 3208-3213 [2021-11-16; online 2021-09-13]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
Cover Feature: Engineered Human Induced Pluripotent Cells Enable Genetic Code Expansion in Brain Organoids (ChemBioChem 22/2021)
van Husen LS, Katsori A, Meineke B, ..., Schedin‐Weiss S, Elsässer SJ
Chembiochem 22 (22) 3108-3108 [2021-11-16; online 2021-09-28]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Glucosylceramide synthase deficiency in the heart compromises β1-adrenergic receptor trafficking.
Andersson L, Cinato M, Mardani I, ..., Borén J, Levin MC
Eur. Heart J. 42 (43) 4481-4492 [2021-11-14; online 2021-07-24]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
GutMicroNet: an interactive platform for gut microbiome interaction exploration
Arif M, Portlock T, Güngör C, ..., Mardinoglu A, Shoaie S
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Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling.
Meineke B, Heimgärtner J, Craig AJ, ..., Moodie LWK, Elsässer SJ
Front Chem 9 (-) 768535 [2021-11-11; online 2021-11-11]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
Large-scale identification of RBP-RNA interactions by RAPseq refines essentials of post-transcriptional gene regulation
Atanasoai I, Papavasileiou S, Preiß N, Kutter C
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Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
CRISPRi as a Tool to Repress Multiple Copies of Extracellular Polymeric Substances (EPS)-Related Genes in the Cyanobacterium Synechocystis sp. PCC 6803.
Santos M, Pacheco CC, Yao L, Hudson EP, Tamagnini P
Life (Basel) 11 (11) - [2021-11-06; online 2021-11-06]
Paul Hudson SciLifeLab Fellow
DOI Crossref
Global patterns and rates of habitat transitions across the eukaryotic tree of life
Jamy M, Biwer C, Vaulot D, ..., Massana R, Burki F
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Fabien Burki Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis.
Matias MI, Yong CS, Foroushani A, ..., Taylor N, Dardalhon V
Cell Reports 37 (5) 109911 [2021-11-02; online 2021-11-04]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Protein allocation and utilization in the versatile chemolithoautotroph Cupriavidus necator.
Jahn M, Crang N, Janasch M, ..., Asplund-Samuelsson J, Hudson EP
Elife 10 (-) - [2021-11-01; online 2021-11-01]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF.
Hausmann A, Felmy B, Kunz L, ..., Sellin ME, Hardt WD
J. Exp. Med. 218 (11) - [2021-11-01; online 2021-09-16]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Safety and Efficacy Assessments to Take Antioxidants in Glioblastoma Therapy: From In Vitro Experiences to Animal and Clinical Studies.
Turkez H, Tozlu OO, Arslan ME, Mardinoglu A
Neurochem Int 150 (-) 105168 [2021-11-00; online 2021-08-25]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Effective sequence similarity detection with strobemers.
Sahlin K
Genome Res 31 (11) 2080-2094 [2021-11-00; online 2021-10-19]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram.
Biancalani T, Scalia G, Buffoni L, ..., Macosko EZ, Regev A
Nat. Methods 18 (11) 1352-1362 [2021-11-00; online 2021-10-28]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Cycling between growth and production phases increases cyanobacteria bioproduction of lactate.
Shabestary K, Hernández HP, Miao R, ..., Branco Dos Santos F, Hudson EP
Metab. Eng. 68 (-) 131-141 [2021-11-00; online 2021-10-01]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
5´XP sRNA-seq: efficient identification of transcripts with and without 5´ phosphorylation reveals evolutionary conserved small RNA.
Kugelberg U, Nätt D, Skog S, Kutter C, Öst A
RNA Biol 18 (11) 1588-1599 [2021-11-00; online 2020-12-31]
Claudia Kutter SciLifeLab Fellow
DOI Crossref
Stratification of the Gut Microbiota Composition Landscape Across the Alzheimer’s Disease Continuum in a Turkish Cohort
Yıldırım S, Nalbantoğlu ÖU, Bayraktar A, ..., Köseoğlu E, Hanoğlu L
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Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Event-triggered STED imaging
Alvelid J, Damenti M, Testa I
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Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Revealing the Molecular Mechanisms of Alzheimer's Disease Based on Network Analysis.
Bayraktar A, Lam S, Altay O, ..., Shoaie S, Mardinoglu A
Int J Mol Sci 22 (21) 11556 [2021-10-26; online 2021-10-26]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
The Lon protease temporally restricts polar cell differentiation events during the Caulobacter cell cycle.
Omnus DJ, Fink MJ, Szwedo K, Jonas K
Elife 10 (-) - [2021-10-25; online 2021-10-25]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Investigation of the individual human sulfatome in plasma and urine samples reveals an age-dependency.
Correia MSP, Thapa B, Vujasinovic M, Löhr JM, Globisch D
RSC Adv. 11 (55) 34788-34794 [2021-10-25; online 2021-10-28]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Chemoselective and Highly Sensitive Quantification of Gut Microbiome and Human Metabolites.
Lin W, Conway LP, Vujasinovic M, Löhr JM, Globisch D
Angew. Chem. Int. Ed. Engl. 60 (43) 23232-23240 [2021-10-18; online 2021-09-17]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Chemoselective and Highly Sensitive Quantification of Gut Microbiome and Human Metabolites
Lin W, Conway LP, Vujasinovic M, Löhr J‐, Globisch D
Angewandte Chemie 133 (43) 23420-23428 [2021-10-18; online 2021-09-17]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Identification of electroporation sites in the complex lipid organization of the plasma membrane
Rems L, Tang X, Zhao F, ..., Testa I, Delemotte L
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Ilaria Testa Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions.
Andersson A, Larsson L, Stenbeck L, ..., Engblom C, Lundeberg J
Nat Commun 12 (1) 6012 [2021-10-14; online 2021-10-14]
SciLifeLab Fellow
PubMed DOI Crossref
Herpes Simplex Virus 1 and 2 Infections during Differentiation of Human Cortical Neurons.
Bergström P, Trybala E, Eriksson CE, ..., Zetterberg H, Bergström T
Viruses 13 (10) - [2021-10-14; online 2021-10-14]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
The Assessment of Selected miRNA Profile in Familial Mediterranean Fever.
Kahraman CY, Egin ME, Tatar A, Turkez H, Mardinoglu A
Biomed Res Int 2021 (-) 6495700 [2021-10-13; online 2021-10-13]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Diversity and ecology of protists revealed by metabarcoding.
Burki F, Sandin MM, Jamy M
Curr. Biol. 31 (19) R1267-R1280 [2021-10-11; online 2021-10-13]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Combined Metabolic Activators Decrease Liver Steatosis by Activating Mitochondrial Metabolism in Hamsters Fed with a High-Fat Diet.
Yang H, Mayneris-Perxachs J, Boqué N, ..., Mardinoglu A, Caimari A
Biomedicines 9 (10) - [2021-10-11; online 2021-10-11]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases
Gahura O, Mühleip A, Hierro-Yap C, ..., Zíková A, Amunts A
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Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines.
Lin W, Yang Z, Kaur A, ..., Löhr JM, Globisch D
RSC Chem Biol 2 (5) 1479-1483 [2021-10-07; online 2021-08-12]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Nanoengineered DNA origami with repurposed TOP1 inhibitors targeting myeloid cells for the mitigation of neuroinflammation
Zhu K, Wang Y, Sarlus H, ..., Högberg B, Harris RA
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Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Differential susceptibility of rat primary neurons and neural stem cells to PFOS and PFOA toxicity.
Pierozan P, Karlsson O
Toxicol. Lett. 349 (-) 61-68 [2021-10-01; online 2021-06-11]
Oskar Karlsson SciLifeLab Fellow
DOI Crossref
Deep mutational scan of a drug efflux pump reveals its structure-function landscape
Meier G, Thavarasah S, Ehrenbolger K, ..., Barandun J, Seeger MA
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Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?
Ballante F, Kooistra AJ, Kampen S, de Graaf C, Carlsson J
Pharmacol Rev 73 (4) 527-565 [2021-10-00; online 2021-12-16]
Jens Carlsson SciLifeLab Fellow
DOI Crossref
Sinking enhances the degradation of organic particles by marine bacteria
Alcolombri U, Peaudecerf FJ, Fernandez VI, ..., Lee KS, Stocker R
Nat. Geosci. 14 (10) 775-780 [2021-10-00; online 2021-09-23]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Refining the amyloid β peptide and oligomer fingerprint ambiguities in Alzheimer's disease: Mass spectrometric molecular characterization in brain, cerebrospinal fluid, blood, and plasma.
Michno W, Blennow K, Zetterberg H, Brinkmalm G
J. Neurochem. 159 (2) 234-257 [2021-10-00; online 2021-07-27]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Promising potential of boron compounds against Glioblastoma: In Vitro antioxidant, anti-inflammatory and anticancer studies.
Turkez H, Arslan ME, Tatar A, Mardinoglu A
Neurochem Int 149 (-) 105137 [2021-10-00; online 2021-07-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
GABA induces a hormonal counter-regulatory response in subjects with long-standing type 1 diabetes.
Espes D, Liljebäck H, Hill H, ..., Caballero-Corbalan J, Carlsson PO
BMJ Open Diabetes Res Care 9 (1) - [2021-10-00; online 2021-10-13]
Daniel Espes SciLifeLab Fellow
PubMed DOI Crossref
Corrigendum: Ancient microRNA profiles of 14,300-yr-old canid samples confirm taxonomic origin and provide glimpses into tissue-specific gene regulation from the Pleistocene.
Fromm B, Tarbier M, Smith O, ..., Gilbert MTP, Friedländer MR
RNA 27 (10) 1291 [2021-10-00; online 2021-09-18]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients.
Zeybel M, Altay O, Arif M, ..., Borén J, Mardinoglu A
Mol Syst Biol 17 (10) e10459 [2021-10-00; online 2021-10-26]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Association of levonorgestrel intrauterine devices with stress reactivity, mental health, quality of life and sexual functioning: A systematic review.
Bürger Z, Bucher AM, Comasco E, ..., Kogler L, Derntl B
Front Neuroendocrinol 63 (-) 100943 [2021-10-00; online 2021-08-20]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
A practical guide to large-scale docking.
Bender BJ, Gahbauer S, Luttens A, ..., Irwin JJ, Shoichet BK
Nat Protoc 16 (10) 4799-4832 [2021-10-00; online 2021-09-24]
Andreas Luttens DDLS Fellow Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
An evaluation of a FluoroSpot assay as a diagnostic tool to determine SARS-CoV-2 specific T cell responses.
Mangsbo SM, Havervall S, Laurén I, ..., Klingström J, Thålin C
PLoS ONE 16 (9) e0258041 [2021-09-30; online 2021-09-30]
Gustaf Christoffersson SciLifeLab Fellow
DOI Crossref
16S rRNA gene sequences of Candidatus Methylumidiphilus ( Methylococcales ), a putative methanotrophic genus in lakes and ponds
Rissanen AJ, Buck M, Peura S
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Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Improved Radiolytic Stability of a 68Ga-labelled Collagelin Analogue for the Imaging of Fibrosis.
Velikyan I, Rosenström U, Rosestedt M, Eriksson O, Antoni G
Pharmaceuticals (Basel, Switzerland) 14 (10) - [2021-09-28; online 2021-09-28]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69.
Persson J, Puuvuori E, Zhang B, ..., Eriksson O, Löfblom J
Sci Rep 11 (1) 19151 [2021-09-27; online 2021-09-27]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer's and Parkinson's Diseases.
Lam S, Hartmann N, Benfeitas R, ..., Knight R, Mardinoglu A
Biomedicines 9 (10) - [2021-09-24; online 2021-09-24]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Editorial: The Role of Biomembranes and Biophysics in Immune Cell Signaling.
Shi Y, Sezgin E, Chen W
Front Immunol 12 (-) 740373 [2021-09-24; online 2021-09-24]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Optimization of an Imidazo[1,2-a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy.
McCoull W, Boyd S, Brown MR, ..., Zhu Q, Smith PD
J Med Chem 64 (18) 13524-13539 [2021-09-23; online 2021-09-03]
SciLifeLab Fellow Yumeng Mao
DOI Crossref
Author response: The Lon protease temporally restricts polar cell differentiation events during the Caulobacter cell cycle
Omnus DJ, Fink MJ, Szwedo K, Jonas K
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Kristina Jonas SciLifeLab Fellow
DOI Crossref
Author response: Protein allocation and utilization in the versatile chemolithoautotroph Cupriavidus necator
Jahn M, Crang N, Janasch M, ..., Asplund-Samuelsson J, Hudson EP
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Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
A nascent polypeptide sequence modulates DnaA translation elongation in response to nutrient availability.
Felletti M, Romilly C, Wagner EGH, Jonas K
Elife 10 (-) - [2021-09-15; online 2021-09-15]
Kristina Jonas SciLifeLab Fellow
DOI Crossref
Protein-lipid interaction at low pH induces oligomerisation of the MakA cytotoxin from Vibrio cholerae
Nadeem A, Berg A, Pace H, ..., Uhlin BE, Wai SN
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Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells.
von Beek C, Alriksson L, Palle J, ..., Sellin ME, Pejler G
PLoS ONE 16 (9) e0256708 [2021-09-07; online 2021-09-07]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome.
Bacic L, Gaullier G, Sabantsev A, ..., Boulton SJ, Deindl S
Elife 10 (-) - [2021-09-06; online 2021-09-06]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
Genomic Signatures of Sexual Selection on Pollen-Expressed Genes in Arabis alpina
Gutiérrez-Valencia J, Fracassetti M, Horvath R, ..., Kolář F, Slotte T
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SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Multi-omics approaches for revealing the complexity of cardiovascular disease.
Doran S, Arif M, Lam S, ..., Boren J, Mardinoglu A
Brief. Bioinformatics 22 (5) - [2021-09-02; online 2021-03-17]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
The long-time orphan protist Meringosphaera mediterranea Lohmann, 1902 [1903] is a centrohelid heliozoan.
Zlatogursky VV, Shɨshkin Y, Drachko D, Burki F
J. Eukaryot. Microbiol. 68 (5) e12860 [2021-09-00; online 2021-07-12]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
RecA finds homologous DNA by reduced dimensionality search.
Wiktor J, Gynnå AH, Leroy P, ..., Testa I, Elf J
Nature 597 (7876) 426-429 [2021-09-00; online 2021-09-01]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Potential for improved retention rate by personalized antiseizure medication selection: A register-based analysis.
Håkansson S, Karlander M, Larsson D, ..., Zelezniak A, Zelano J
Epilepsia 62 (9) 2123-2132 [2021-09-00; online 2021-07-09]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia.
Draper-Joyce CJ, Bhola R, Wang J, ..., Imlach WL, Christopoulos A
Nature 597 (7877) 571-576 [2021-09-00; online 2021-09-08]
Jens Carlsson SciLifeLab Fellow
DOI Crossref
Phosphorus Regulation of Methane Oxidation in Water From Ice‐Covered Lakes
Sawakuchi HO, Martin G, Peura S, ..., Karlsson J, Bastviken D
J. Geophys. Res. Biogeosci. 126 (9) - [2021-09-00; online 2021-09-12]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Killing two enemies with one stone? Genomics of resistance to two sympatric pathogens in Norway spruce.
Capador-Barreto HD, Bernhardsson C, Milesi P, ..., Stenlid J, Elfstrand M
Mol. Ecol. 30 (18) 4433-4447 [2021-09-00; online 2021-08-05]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19.
Altay O, Arif M, Li X, ..., Uhlén M, Mardinoglu A
Adv Sci (Weinh) 8 (17) e2101222 [2021-09-00; online 2021-06-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Synergies of Systems Biology and Synthetic Biology in Human Microbiome Studies.
Ezzamouri B, Shoaie S, Ledesma-Amaro R
Front Microbiol 12 (-) 681982 [2021-08-31; online 2021-08-31]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Not4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5A.
Allen GE, Panasenko OO, Villanyi Z, ..., Ignatova Z, Collart MA
Cell Reports 36 (9) 109633 [2021-08-31; online 2021-09-02]
SciLifeLab Fellow
DOI Crossref
Algal photosystem I dimer and high resolution model of PSI:plastocyanin complex
Naschberger A, Mosebach L, Tobiasson V, ..., Hippler M, Amunts A
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Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structural basis of LhcbM5-mediated state transitions in green algae.
Amunts A
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Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Repurposing tRNAs for nonsense suppression.
Amunts A
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Alexey Amunts SciLifeLab Fellow
DOI Crossref
Enterotoxigenic Escherichia coli display a distinct growth phase before entry into stationary phase with shifts in tryptophan- fucose- and putrescine metabolism and degradation of neurotransmitter precursors
Joffré E, Xiao X, Correia MSP, ..., Zhu B, Sjöling Å
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Daniel Globisch SciLifeLab Fellow
DOI Crossref
High definition DIC imaging uncovers transient stages of pathogen infection cycles on the surface of human adult stem cell-derived intestinal epithelium
van Rijn JM, Eriksson J, Grüttner J, ..., Svärd SG, Sellin ME
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Mikael Sellin SciLifeLab Fellow
DOI Crossref
Polycomb Repressive Complex 2 shields naïve human pluripotent cells from trophectoderm differentiation
Kumar B, Navarro C, Winblad N, ..., Lanner F, Elsässer SJ
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SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Structure and Sequence-based Computational Approaches to Allosteric Signal Transduction: Application to Electromechanical Coupling in Voltage-gated Ion Channels.
Elbahnsi A, Delemotte L
J. Mol. Biol. 433 (17) 167095 [2021-08-20; online 2021-06-06]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Ion Channels: Intersection of Structure, Function, and Pharmacology.
Moiseenkova-Bell V, Delemotte L, Minor DL
J. Mol. Biol. 433 (17) 167102 [2021-08-20; online 2021-06-11]
Lucie Delemotte SciLifeLab Fellow
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Community composition of aquatic fungi across the thawing Arctic.
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Combined Metabolic Activators Improve Cognitive Functions without Altering Motor Scores in Parkinson’s Disease
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The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output.
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An open state of a voltage-gated sodium channel involving a π-helix and conserved pore-facing Asparagine
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Anticancer effects of novel NSAIDs derivatives on cultured human glioblastoma cells.
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A network-based approach reveals the dysregulated transcriptional regulation in non-alcohol fatty liver disease
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Combined Metabolic Activators Improves Cognitive Functions in Alzheimer’s Disease
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Pascal Milesi SciLifeLab Fellow
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Allosteric effect of nanobody binding on ligand-specific active states of the β2-Adrenergic Receptor
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COVseq is a cost-effective workflow for mass-scale SARS-CoV-2 genomic surveillance
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Magda Bienko SciLifeLab Fellow
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Synthetic metabolic pathways for conversion of CO 2 into secreted short-to medium-chain hydrocarbons using cyanobacteria
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Recent Progress in the Molecular Imaging of Nonalcoholic Fatty Liver Disease.
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Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis.
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The spatial transcriptomic landscape of the healing intestine following damage
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iNetModels 2.0: an interactive visualization and database of multi-omics data.
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Nucleic Acids Res. 49 (W1) W271-W276 [2021-07-02; online 2021-04-14]
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Fungal community composition along a gradient of permafrost thaw
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Sari Peura SciLifeLab Fellow
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The Effect of the Molecular Weight of Polyvinylpyrrolidone and the Model Drug on Laser-Induced In Situ Amorphization.
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Molecules 26 (13) 4035 [2021-07-01; online 2021-07-01]
Alexandra Teleki SciLifeLab Fellow
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Editorial: NK-Myeloid Cell Interactions in the Tumor Microenvironment: Implications for Cancer Immunotherapy.
Wennerberg E, Lundqvist A, Mao Y, Mougiakakos D
Front Immunol 12 (-) 718844 [2021-07-01; online 2021-07-01]
SciLifeLab Fellow Yumeng Mao
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CRISPR/Cas9 deletions induce adverse on-target genomic effects leading to functional DNA in human cells
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Claudia Kutter SciLifeLab Fellow
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Simultaneous detection of SARS-CoV-2 and pandemic (H1N1) 2009 virus with real-time isothermal platform.
Yu L, Wang J, Li X, ..., Guo X, Yin X
Heliyon 7 (7) e07584 [2021-07-00; online 2021-07-15]
SciLifeLab Fellow
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Safety Assessments of Nickel Boride Nanoparticles on the Human Pulmonary Alveolar Cells by Using Cell Viability and Gene Expression Analyses.
Türkez H, Arslan ME, Sönmez E, ..., Açikyildiz M, Mardinoğlu A
Biol Trace Elem Res 199 (7) 2602-2611 [2021-07-00; online 2020-09-09]
Adil Mardinoglu SciLifeLab Fellow
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STED and parallelized RESOLFT optical nanoscopy of the tubular endoplasmic reticulum and its mitochondrial contacts in neuronal cells.
Damenti M, Coceano G, Pennacchietti F, Bodén A, Testa I
Neurobiol. Dis. 155 (-) 105361 [2021-07-00; online 2021-04-12]
Ilaria Testa SciLifeLab Fellow
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Recommendations for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samples.
Kubik S, Marques AC, Xing X, ..., Willig A, Xu Z
Clin. Microbiol. Infect. 27 (7) 1036.e1-1036.e8 [2021-07-00; online 2021-04-02]
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On the origin of the widespread self-compatible allotetraploid Capsella bursa-pastoris (Brassicaceae).
Bachmann JA, Tedder A, Fracassetti M, ..., Köhler C, Slotte T
Heredity (Edinb) 127 (1) 124-134 [2021-07-00; online 2021-04-19]
SciLifeLab Fellow Tanja Slotte
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Molecular Dynamics Simulations of Ion Channels.
Carnevale V, Delemotte L, Howard RJ
Trends Biochem. Sci. 46 (7) 621-622 [2021-07-00; online 2021-04-30]
Lucie Delemotte SciLifeLab Fellow
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Effects of 6 weeks of treatment with dapagliflozin, a sodium-glucose co-transporter-2 inhibitor, on myocardial function and metabolism in patients with type 2 diabetes: A randomized, placebo-controlled, exploratory study.
Oldgren J, Laurila S, Åkerblom A, ..., Oscarsson J, Nuutila P
Diabetes Obes Metab 23 (7) 1505-1517 [2021-07-00; online 2021-03-12]
Olof Eriksson SciLifeLab Fellow
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Distinct genetic regions are associated with differential population susceptibility to chemical exposures.
Kosnik MB, Enroth S, Karlsson O
Environ Int 152 (-) 106488 [2021-07-00; online 2021-03-10]
Oskar Karlsson SciLifeLab Fellow
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DNA Origami Penetration in Cell Spheroid Tissue Models is Enhanced by Wireframe Design.
Wang Y, Benson E, Fördős F, ..., Teixeira AI, Högberg B
Adv. Mater. Weinheim 33 (29) e2008457 [2021-07-00; online 2021-06-06]
Erik Benson SciLifeLab Fellow
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Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator.
Kaltsouni E, Fisher PM, Dubol M, ..., Comasco E, Sundström-Poromaa I
Neuropsychopharmacology 46 (8) 1460-1467 [2021-07-00; online 2021-04-29]
Erika Comasco SciLifeLab Fellow
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A single-cell type transcriptomics map of human tissues.
Karlsson M, Zhang C, Méar L, ..., Uhlén M, Lindskog C
Sci Adv 7 (31) - [2021-07-00; online 2021-07-28]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
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DNA Blocks the Lethal Effect of Human Beta-Defensin 2 Against Neisseria meningitidis.
Wassing GM, Lidberg K, Sigurlásdóttir S, ..., Jonas K, Jonsson AB
Front Microbiol 12 (-) 697232 [2021-06-30; online 2021-06-30]
Kristina Jonas SciLifeLab Fellow
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The Lon protease temporally restricts polar cell differentiation events during the Caulobacter cell cycle
Omnus DJ, Fink MJ, Szwedo K, Jonas K
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Kristina Jonas SciLifeLab Fellow
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Analysis at single-cell resolution identifies a stable mammalian tRNA-mRNA interface and increased translation efficiency in neurons
Gao W, Gallardo-Dodd CJ, Kutter C
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Claudia Kutter SciLifeLab Fellow
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Cisplatin inhibits frequency and suppressive activity of monocytic myeloid-derived suppressor cells in cancer patients.
Van Wigcheren GF, De Haas N, Mulder TA, ..., Hato SV, De Vries IJM
Oncoimmunology 10 (1) 1935557 [2021-06-27; online 2021-06-27]
SciLifeLab Fellow Yumeng Mao
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Pesticide-induced multigenerational effects on amphibian reproduction and metabolism.
Karlsson O, Svanholm S, Eriksson A, ..., Jernerén F, Berg C
Sci. Total Environ. 775 (-) 145771 [2021-06-25; online 2021-02-11]
Oskar Karlsson SciLifeLab Fellow
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Engineered human induced pluripotent cells enable genetic code expansion in brain organoids
van Husen LS, Katsori AM, Meineke B, ..., Schedin-Weiss S, Elsässer SJ
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SciLifeLab Fellow Simon Elsässer
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COVseq is a cost-effective workflow for mass-scale SARS-CoV-2 genomic surveillance.
Simonetti M, Zhang N, Harbers L, ..., Ghisetti V, Crosetto N
Nat Commun 12 (1) 3903 [2021-06-23; online 2021-06-23]
Magda Bienko SciLifeLab Fellow
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Accelerated regression-based summary statistics for discrete stochastic systems via approximate simulators.
Jiang RM, Wrede F, Singh P, Hellander A, Petzold LR
BMC Bioinformatics 22 (1) 339 [2021-06-23; online 2021-06-23]
Prashant Singh SciLifeLab Fellow
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The Influence of Drug-Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles.
Hempel NJ, Merkl P, Knopp MM, ..., Sotiriou GA, Löbmann K
Pharmaceutics 13 (6) 917 [2021-06-21; online 2021-06-21]
Alexandra Teleki SciLifeLab Fellow
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Next generation plasma proteome profiling of COVID-19 patients with mild to moderate symptoms
Zhong W, Altay O, Arif M, ..., Uhlén M, Fagerberg L
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Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
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CLEO®/Europe-EQEC 2021, One Page Summary Template Volumetric RESOLFT fluorescence nanoscopy
Testa I
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Ilaria Testa SciLifeLab Fellow
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Flexible seed size enables ultra-fast and accurate read alignment
Sahlin K
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Kristoffer Sahlin SciLifeLab Fellow
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Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome
Bacic L, Gaullier G, Sabantsev A, ..., Boulton SJ, Deindl S
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SciLifeLab Fellow Sebastian Deindl
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Application of high-throughput 5'P sequencing for the study of co-translational mRNA decay.
Zhang Y, Pelechano V
STAR Protoc 2 (2) 100447 [2021-06-18; online 2021-03-31]
SciLifeLab Fellow
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Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2.
Roxhed N, Bendes A, Dale M, ..., Fredolini C, Schwenk JM
Nat Commun 12 (1) 3695 [2021-06-17; online 2021-06-17]
SciLifeLab Fellow Simon Elsässer
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Means, Motive, and Opportunity: Do Non-Islet-Reactive Infiltrating T Cells Contribute to Autoimmunity in Type 1 Diabetes?
Rodriguez-Calvo T, Christoffersson G, Bender C, ..., Kent SC, James EA
Front Immunol 12 (-) 683091 [2021-06-16; online 2021-06-16]
Gustaf Christoffersson SciLifeLab Fellow
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Newly synthesized RNA Sequencing Characterizes Transcription Dynamics in Three Pluripotent States
Shao R, Kumar B, Lidschreiber K, ..., Cramer P, Elsässer SJ
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SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Leveraging breeding programs and genomic data in Norway spruce (Picea abies L. Karst) for GWAS analysis.
Chen ZQ, Zan Y, Milesi P, ..., Lascoux M, Wu HX
Genome Biol. 22 (1) 179 [2021-06-13; online 2021-06-13]
Pascal Milesi SciLifeLab Fellow
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Systems analysis reveals ageing-related perturbations in retinoids and sex hormones in Alzheimer’s and Parkinson’s diseases
Lam S, Hartmann N, Benfeitas R, ..., Knight R, Mardinoglu A
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Learning the Regulatory Code of Gene Expression.
Zrimec J, Buric F, Kokina M, Garcia V, Zelezniak A
Front Mol Biosci 8 (-) 673363 [2021-06-10; online 2021-06-10]
Aleksej Zelezniak SciLifeLab Fellow
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Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet.
Hempel NJ, Merkl P, Asad S, ..., Sotiriou GA, Löbmann K
Mol. Pharm. 18 (6) 2254-2262 [2021-06-07; online 2021-05-05]
Alexandra Teleki SciLifeLab Fellow
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Author Correction: A molecular timescale for eukaryote evolution with implications for the origin of red algal-derived plastids.
Strassert JFH, Irisarri I, Williams TA, Burki F
Nat Commun 12 (1) 3574 [2021-06-07; online 2021-06-07]
Fabien Burki SciLifeLab Fellow
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STED super-resolution imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes
Carravilla P, Dasgupta A, Zhurgenbayeva G, ..., Sezgin E, Eggeling C
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Erdinc Sezgin SciLifeLab Fellow
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The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function.
Oftedal BE, Maio S, Handel AE, ..., Maizels RM, Holländer GA
Commun Biol 4 (1) 681 [2021-06-03; online 2021-06-03]
Erdinc Sezgin SciLifeLab Fellow
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Imaging of the Glucagon Receptor in Subjects with Type 2 Diabetes.
Eriksson O, Velikyan I, Haack T, ..., Tillner J, Wagner M
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 62 (6) 833-838 [2021-06-01; online 2020-10-23]
Olof Eriksson SciLifeLab Fellow
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Unboxing mutations: Connecting mutation types with evolutionary consequences.
Berdan EL, Blanckaert A, Slotte T, ..., Westram AM, Fragata I
Mol. Ecol. 30 (12) 2710-2723 [2021-06-00; online 2021-05-19]
SciLifeLab Fellow Tanja Slotte
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Towards policies that capture the expected value of biomolecular diversity for drug discovery, human health, and well-being.
Pesic M, Egamberdieva D, Kolodziejczyk B, ..., Neergheen VS, Kagansky A
Biol Futur 72 (2) 119-125 [2021-06-00; online 2020-09-07]
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More Than Just Letters and Chemistry: Genomics Goes Mechanics.
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SciLifeLab Fellow Sebastian Deindl
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Following spatial Aβ aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics.
Michno W, Stringer KM, Enzlein T, ..., Edwards FA, Hanrieder J
Sci Adv 7 (25) - [2021-06-00; online 2021-06-16]
SciLifeLab Fellow Wojciech Michno
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Correction to: Towards policies that capture the expected value of biomolecular diversity for drug discovery, human health, and well-being.
Pesic M, Egamberdieva D, Kolodziejczyk B, ..., Neergheen VS, Kagansky A
Biol Futur 72 (2) 127 [2021-06-00; online 2021-09-24]
SciLifeLab Fellow Simon Elsässer
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Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides.
Muntjewerff EM, Tang K, Lutter L, ..., van den Bogaart G, Mahata SK
Acta Physiol 232 (2) e13655 [2021-06-00; online 2021-05-06]
Gustaf Christoffersson SciLifeLab Fellow
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Synthetic antigen-presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of T cell immunological synapses
Céspedes PF, Jainarayanan A, Fernández-Messina L, ..., Sánchez-Madrid F, Dustin ML
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Erdinc Sezgin SciLifeLab Fellow
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Using TIF-Seq2 to investigate association between 5´ and 3´mRNA ends.
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Meth. Enzymol. 655 (-) 85-118 [2021-05-28; online 2021-05-28]
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Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium
Mehregan A, Pérez-Conesa S, Zhuang Y, ..., Ulens C, Delemotte L
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Lucie Delemotte SciLifeLab Fellow
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Informing Pharmacokinetic Models With Physiological Data: Oral Population Modeling of L-Serine in Humans.
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Comparative Genomics Analysis of Keratin-Degrading Chryseobacterium Species Reveals Their Keratinolytic Potential for Secondary Metabolite Production.
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Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction.
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Freshwater Chlorobia Exhibit Metabolic Specialization among Cosmopolitan and Endemic Populations.
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The Genomic Architecture and Evolutionary Fates of Supergenes.
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A microscopy-compatible temperature regulation system for single-cell phenotype analysis - demonstrated by thermoresponse mapping of microalgae.
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Synthetic Biology in Cyanobacteria and Applications for Biotechnology
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Paul Hudson SciLifeLab Fellow
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Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity.
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Lucie Delemotte SciLifeLab Fellow
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Ilaria Testa SciLifeLab Fellow
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Strategies for Constructing and Operating DNA Origami Linear Actuators.
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Erik Benson SciLifeLab Fellow
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Mikael Sellin SciLifeLab Fellow
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Can molecular dynamics simulations improve the structural accuracy and virtual screening performance of GPCR models?
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The Protein Quality Control Network in Caulobacter crescentus.
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Kristina Jonas SciLifeLab Fellow
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Informing NMR experiments with molecular dynamics simulations to characterize the dominant activated state of the KcsA ion channel.
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Lucie Delemotte SciLifeLab Fellow
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How Does Liquid-Liquid Phase Separation in Model Membranes Reflect Cell Membrane Heterogeneity?
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Erdinc Sezgin SciLifeLab Fellow
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Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth.
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Genome-wide mapping of G-quadruplex structures with CUT&Tag
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Author response: Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI.
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers.
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Mikael Sellin SciLifeLab Fellow
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Scalable machine learning-assisted model exploration and inference using Sciope.
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Prashant Singh SciLifeLab Fellow
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PET Imaging of GPR44 by Antagonist [11C]MK-7246 in Pigs.
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Olof Eriksson SciLifeLab Fellow
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Mol. Cell 81 (8) 1715-1731.e6 [2021-04-15; online 2021-03-29]
Anniina Vihervaara SciLifeLab Fellow
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A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation.
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SciLifeLab Fellow Sebastian Deindl
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Slow Protein Turnover Explains Limited Protein-Level Response to Diurnal Transcriptional Oscillations in Cyanobacteria.
Karlsen J, Asplund-Samuelsson J, Jahn M, Vitay D, Hudson EP
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Paul Hudson SciLifeLab Fellow
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Single cell genomics reveals plastid-lacking Picozoa are close relatives of red algae
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Fabien Burki SciLifeLab Fellow
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DNA methylation in cord blood in association with prenatal depressive symptoms.
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Erika Comasco SciLifeLab Fellow
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RNA degradation analysis reveals ribosome dynamics in complex microbiome samples
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Emil Marklund SciLifeLab Fellow Sebastian Deindl
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Revealing the Metabolic Alterations during Biofilm Development of Burkholderia cenocepacia Based on Genome-Scale Metabolic Modeling.
Altay O, Zhang C, Turkez H, ..., Uhlén M, Mardinoglu A
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Adil Mardinoglu SciLifeLab Fellow
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Resin-acid derivatives bind to multiple sites on the voltage-sensor domain of the Shaker potassium channel.
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Lucie Delemotte SciLifeLab Fellow
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Genome Size Reduction and Transposon Activity Impact tRNA Gene Diversity While Ensuring Translational Stability in Birds.
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Global and temporal state of the human gut microbiome in health and disease
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Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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The genome of Draba nivalis shows signatures of adaptation to the extreme environmental stresses of the Arctic.
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Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains.
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Patrick Sandoz SciLifeLab Fellow
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Longitudinal Assessment of 11C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes.
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Daniel Espes Olof Eriksson SciLifeLab Fellow
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Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography.
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BMJ Open Diabetes Res Care 9 (1) - [2021-04-00; online 2021-04-28]
Olof Eriksson SciLifeLab Fellow
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Drug Occupancy Assessment at the Glucose-Dependent Insulinotropic Polypeptide Receptor by Positron Emission Tomography.
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Olof Eriksson SciLifeLab Fellow
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A genomic catalog of Earth’s microbiomes
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Nat Biotechnol 39 (4) 499-509 [2021-04-00; online 2020-11-09]
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A nascent polypeptide sequence modulates DnaA translation elongation in response to nutrient availability
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Kristina Jonas SciLifeLab Fellow
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A FOXN1 mutation competitively displaces wild-type FOXN1 from higher-order nuclear condensates to cause immunodeficiency
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Erdinc Sezgin SciLifeLab Fellow
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A molecular timescale for eukaryote evolution with implications for the origin of red algal-derived plastids.
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Fabien Burki SciLifeLab Fellow
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Protein allocation and utilization in the versatile chemolithoautotroph Cupriavidus necator
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Paul Hudson SciLifeLab Fellow
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Addressing the heterogeneity in liver diseases using biological networks.
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Adil Mardinoglu SciLifeLab Fellow
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A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo
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Erdinc Sezgin SciLifeLab Fellow
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The long-time orphan protist Meringosphaera mediterranea Lohmann, 1902 [1903] is a centrohelid heliozoan
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Fabien Burki SciLifeLab Fellow
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Engineering of Ancestors as a Tool to Elucidate Structure, Mechanism, and Specificity of Extant Terpene Cyclase.
Schriever K, Saenz-Mendez P, Rudraraju RS, ..., Schnell R, Syrén PO
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Paul Hudson SciLifeLab Fellow
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Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
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Alexey Amunts SciLifeLab Fellow
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3D-printing of solid lipid tablets from emulsion gels.
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Alexandra Teleki SciLifeLab Fellow
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High Expression of LINC01268 is Positively Associated with Hepatocellular Carcinoma Progression via Regulating MAP3K7.
Jin X, Fu W, Li D, ..., Kutter C, Li Y
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Claudia Kutter SciLifeLab Fellow
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Expanding functional protein sequence spaces using generative adversarial networks
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Nat Mach Intell 3 (4) 324-333 [2021-03-04; online 2021-03-04]
Aleksej Zelezniak SciLifeLab Fellow
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Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey.
Alkurt G, Murt A, Aydin Z, ..., Dinler Doganay G, Doganay HL
PLoS ONE 16 (3) e0247865 [2021-03-03; online 2021-03-03]
Adil Mardinoglu SciLifeLab Fellow
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Phosphodiesterase 4A confers resistance to PGE2-mediated suppression in CD25+ /CD54+ NK cells.
Chen Z, Yang Y, Neo SY, ..., Sarhan D, Lundqvist A
EMBO Rep. 22 (3) e51329 [2021-03-03; online 2021-01-22]
SciLifeLab Fellow Yumeng Mao
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ZFP207 controls pluripotency by multiple post-transcriptional mechanisms
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Claudia Kutter SciLifeLab Fellow
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Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson's disease.
Rosario D, Bidkhori G, Lee S, ..., Mardinoglu A, Shoaie S
Cell Reports 34 (9) 108807 [2021-03-02; online 2021-03-04]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Ulipristal Acetate for Treatment of Premenstrual Dysphoric Disorder: A Proof-of-Concept Randomized Controlled Trial.
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Am J Psychiatry 178 (3) 256-265 [2021-03-01; online 2020-12-10]
Erika Comasco SciLifeLab Fellow
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Comprehensive analysis of chemical and biological problems associated with browning agents used in aquatic studies
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Sarahi Garcia Sari Peura SciLifeLab Fellow
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Spatial Regulation of T-Cell Signaling by Programmed Death-Ligand 1 on Wireframe DNA Origami Flat Sheets.
Fang T, Alvelid J, Spratt J, ..., Testa I, Teixeira AI
ACS Nano 15 (2) 3441-3452 [2021-02-23; online 2021-02-08]
Ilaria Testa SciLifeLab Fellow
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High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium.
van Rijn JM, Eriksson J, Grüttner J, ..., Svärd SG, Sellin ME
MBio 13 (1) e0002222 [2021-02-22; online 2022-02-01]
Mikael Sellin SciLifeLab Fellow
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Chenodeoxycholic Acid Modulates Bile Acid Synthesis Independent of Fibroblast Growth Factor 19 in Primary Human Hepatocytes.
Johansson H, Søndergaard JN, Jorns C, Kutter C, Ellis ECS
Front Endocrinol (Lausanne) 11 (-) 554922 [2021-02-22; online 2021-02-22]
Claudia Kutter SciLifeLab Fellow
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Comparison of two arylsulfatases for targeted mass spectrometric analysis of microbiota-derived metabolites.
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Mechanism of membrane-tethered mitochondrial protein synthesis.
Itoh Y, Andréll J, Choi A, ..., Battersby BJ, Amunts A
Science (New York, N.Y.) 371 (6531) 846-849 [2021-02-19; online 2021-02-20]
Alexey Amunts SciLifeLab Fellow
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Combined Metabolic Activators decrease liver steatosis by activating mitochondrial metabolism in a Golden Syrian hamster study
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Adil Mardinoglu SciLifeLab Fellow
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CO2 fixation gets a second chance
Janasch M, Hudson EP
Nat Catal 4 (2) 94-95 [2021-02-19; online 2021-02-19]
Paul Hudson SciLifeLab Fellow
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Acute kidney injury leading to CKD is associated with a persistence of metabolic dysfunction and hypertriglyceridemia.
Harzandi A, Lee S, Bidkhori G, ..., Shoaie S, Sharpe CC
iScience 24 (2) 102046 [2021-02-19; online 2021-01-09]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.
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Mol. Cell 81 (4) 767-783.e11 [2021-02-18; online 2020-12-16]
SciLifeLab Fellow Sebastian Deindl
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PhylEx: Accurate reconstruction of clonal structure via integrated analysis of bulk DNA-seq and single cell RNA-seq data
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Camilla Engblom SciLifeLab Fellow
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Ancient microRNA profiles of 14,300-yr-old canid samples confirm taxonomic origin and provide glimpses into tissue-specific gene regulation from the Pleistocene.
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DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
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Anaerobic oxidation of methane in sediments of a nitrate-rich, oligo-mesotrophic boreal lake
Rissanen AJ, Jilbert T, Simojoki A, ..., Peura S, Jäntti H
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Sari Peura SciLifeLab Fellow
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Author Correction: Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis.
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Nat Commun 12 (1) 992 [2021-02-08; online 2021-02-08]
Kristoffer Sahlin SciLifeLab Fellow
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The glycosphingolipid inhibitor eliglustat inhibits autophagy in osteoclasts to increase bone mass and reduce myeloma bone disease
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Erdinc Sezgin SciLifeLab Fellow
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The Reactobiome Unravels a New Paradigm in Human Gut Microbiome Metabolism
Bidkhori G, Lee S, Edwards LA, ..., Ehrlich SD, Shoaie S
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Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Targeted Gene Candidates for Treatment and Early Diagnosis of Age-Related Macular Degeneration.
Cinici E, Caglar O, Arslan ME, ..., Mardinoglu A, Turkez H
Biomed Res Int 2021 (-) 6620900 [2021-02-02; online 2021-02-02]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Environmental enrichment induces epigenomic and genome organization changes relevant for cognitive function
Espeso-Gil S, Holik A, Bonnin S, ..., Hor CN, Ossowski S
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Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Bistability in oxidative stress response determines the migration behavior of phytoplankton in turbulence.
Carrara F, Sengupta A, Behrendt L, Vardi A, Stocker R
Proc. Natl. Acad. Sci. U.S.A. 118 (5) - [2021-02-02; online 2021-01-27]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Wide range of metabolic adaptations to the acquisition of the Calvin cycle revealed by comparison of microbial genomes.
Asplund-Samuelsson J, Hudson EP
PLoS Comput Biol 17 (2) e1008742 [2021-02-00; online 2021-02-08]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics.
Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan DP, Lundberg E
Nature 590 (7847) 649-654 [2021-02-00; online 2021-02-24]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1.
Rosestedt M, Velikyan I, Rosenström U, ..., Nordeman P, Eriksson O
Nucl. Med. Biol. 93 (-) 54-62 [2021-02-00; online 2020-11-28]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Optofluidic Raman-activated cell sorting for targeted genome retrieval or cultivation of microbial cells with specific functions.
Lee KS, Pereira FC, Palatinszky M, ..., Wagner M, Stocker R
Nat Protoc 16 (2) 634-676 [2021-02-00; online 2020-12-11]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
NGSpeciesID: DNA barcode and amplicon consensus generation from long-read sequencing data.
Sahlin K, Lim MCW, Prost S
Ecol Evol 11 (3) 1392-1398 [2021-02-00; online 2021-01-11]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Model membrane systems to reconstitute immune cell signaling.
Céspedes PF, Beckers D, Dustin ML, Sezgin E
FEBS J. 288 (4) 1070-1090 [2021-02-00; online 2020-08-03]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Interplay of Nav1.5 Disease-Causing Mutations and Phosphorylation Revealed by Protein Semi-Synthesis and Molecular Dynamics Simulations
Galleano I, Harms H, Choudhury K, ..., Delemotte L, Pless SA
Biophysical Journal 120 (3) 288a [2021-02-00; online 2021-02-00]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Hybrid seed incompatibility in Capsella is connected to chromatin condensation defects in the endosperm.
Dziasek K, Simon L, Lafon-Placette C, ..., Slotte T, Köhler C
PLoS Genet 17 (2) e1009370 [2021-02-00; online 2021-02-11]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Epithelial inflammasomes in the defense against Salmonella gut infection.
Fattinger SA, Sellin ME, Hardt WD
Curr Opin Microbiol 59 (-) 86-94 [2021-02-00; online 2020-10-28]
Mikael Sellin SciLifeLab Fellow
DOI Crossref
Character and environmental lability of cyanobacteria‐derived dissolved organic matter
Patriarca C, Sedano‐Núñez VT, Garcia SL, ..., Tranvik LJ, Hawkes JA
Limnol. Oceanogr. 66 (2) 496-509 [2021-02-00; online 2020-10-09]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Author Correction: Liver macrophages regulate systemic metabolism through non-inflammatory factors.
Morgantini C, Jager J, Li X, ..., Bajgar A, Aouadi M
Nat Metab 3 (2) 287 [2021-02-00; online 2021-01-21]
Claudia Kutter SciLifeLab Fellow
DOI Crossref
Strobemers: an alternative to k-mers for sequence comparison
Sahlin K
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Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Epidemiological modeling in StochSS Live!
Jiang R, Jacob B, Geiger M, ..., Hellander A, Petzold L
Bioinformatics - (-) - [2021-01-29; online 2021-01-29]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Identification of ligand-specific G protein-coupled receptor states and prediction of downstream efficacy via data-driven modeling.
Fleetwood O, Carlsson J, Delemotte L
Elife 10 (-) - [2021-01-28; online 2021-01-28]
Jens Carlsson Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Cellocity: A Python package for analysis of confluent cell layer dynamics
Eriksson J, Styrström D, Sellin M
JOSS 6 (57) 2818 [2021-01-28; online 2021-01-28]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Vertical stratification patterns of methanotrophs and their genetic controllers in water columns of oxygen-stratified boreal lakes.
Rissanen AJ, Saarela T, Jäntti H, ..., Elvert M, Nykänen H
FEMS Microbiol. Ecol. 97 (2) - [2021-01-26; online 2020-12-15]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Author Correction: High-resolution analysis of cell-state transitions in yeast suggests widespread transcriptional tuning by alternative starts.
Chia M, Li C, Marques S, ..., Luscombe NM, van Werven FJ
Genome Biol. 22 (1) 46 [2021-01-25; online 2021-01-25]
SciLifeLab Fellow
PubMed DOI Crossref
Influence of nanobody binding on fluorescence emission, mobility, and organization of GFP-tagged proteins.
Schneider F, Sych T, Eggeling C, Sezgin E
iScience 24 (1) 101891 [2021-01-22; online 2020-12-04]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Glycyl-L-Prolyl-L-Glutamate Pseudotripeptides for Treatment of Alzheimer's Disease.
Turkez H, Cacciatore I, Marinelli L, ..., Di Stefano A, Mardinoglu A
Biomolecules 11 (1) - [2021-01-19; online 2021-01-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers.
Li X, Kim W, Arif M, ..., Zhang C, Mardinoglu A
Cancers (Basel) 13 (2) - [2021-01-19; online 2021-01-19]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Direct detection of SARS-CoV-2 using non-commercial RT-LAMP reagents on heat-inactivated samples.
Alekseenko A, Barrett D, Pareja-Sanchez Y, ..., Yin X, Pelechano V
Sci Rep 11 (1) 1820 [2021-01-19; online 2021-01-19]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
COVseq is a cost-effective workflow for mass-scale SARS-CoV-2 genomic surveillance
Simonetti M, Zhang N, Harbers L, ..., Ghisetti V, Crosetto N
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Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Single-Molecule, Super-Resolution, and Functional Analysis of G Protein-Coupled Receptor Behavior Within the T Cell Immunological Synapse.
Felce JH, Parolini L, Sezgin E, ..., Frater J, Dustin ML
Front Cell Dev Biol 8 (-) 608484 [2021-01-18; online 2021-01-18]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
A genomic perspective across Earth’s microbiomes reveals that genome size in Archaea and Bacteria is linked to ecosystem type and trophic strategy
Rodríguez-Gijón A, Nuy JK, Mehrshad M, ..., Woyke T, Garcia SL
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Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Nradd Acts as a Negative Feedback Regulator of Wnt/β-Catenin Signaling and Promotes Apoptosis.
Ozalp O, Cark O, Azbazdar Y, ..., Sezgin E, Ozhan G
Biomolecules 11 (1) - [2021-01-14; online 2021-01-14]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
High-resolution analysis of cell-state transitions in yeast suggests widespread transcriptional tuning by alternative starts.
Chia M, Li C, Marques S, ..., Luscombe NM, van Werven FJ
Genome Biol. 22 (1) 34 [2021-01-14; online 2021-01-14]
SciLifeLab Fellow
DOI Crossref
FOXO1 and FOXO3 cooperatively regulate innate lymphoid cell development
Luu TT, Søndergaard JN, Peña-Pérez L, ..., Månsson R, Kadri N
- - (-) - [2021-01-14; online 2021-01-14]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids.
Geiser P, Di Martino ML, Samperio Ventayol P, ..., Hellström PM, Sellin ME
MBio 12 (1) - [2021-01-12; online 2021-01-12]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae.
Rodríguez-Galán O, García-Gómez JJ, Rosado IV, ..., Kressler D, de la Cruz J
Nucleic Acids Res. 49 (1) 206-220 [2021-01-11; online 2020-12-18]
SciLifeLab Fellow
PubMed DOI Crossref
Bayesian genome scale modelling identifies thermal determinants of yeast metabolism.
Li G, Hu Y, Luo H, ..., Ji B, Nielsen J
Nat Commun 12 (1) 190 [2021-01-08; online 2021-01-08]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria.
Mühleip A, Kock Flygaard R, Ovciarikova J, ..., Sheiner L, Amunts A
Nat Commun 12 (1) 120 [2021-01-05; online 2021-01-05]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Obese mother offspring have hepatic lipidic modulation that contributes to sex-dependent metabolic adaptation later in life.
Savva C, Helguero LA, González-Granillo M, ..., Kutter C, Korach-André M
Commun Biol 4 (1) 14 [2021-01-04; online 2021-01-04]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis.
Sahlin K, Medvedev P
Nat Commun 12 (1) 2 [2021-01-04; online 2021-01-04]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
The effect of Toll-like receptor stimulation on the motility of regulatory T cells.
Chodaczek G, Pagni PP, Christoffersson G, ..., Wegrzyn AS, von Herrath M
J. Autoimmun. 116 (-) 102563 [2021-01-00; online 2020-11-12]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Systems biology based drug repositioning for development of cancer therapy.
Turanli B, Altay O, Borén J, ..., Arga KY, Mardinoglu A
Semin. Cancer Biol. 68 (-) 47-58 [2021-01-00; online 2019-09-27]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease.
Asad S, Wegler C, Ahl D, ..., Artursson P, Teleki A
J Pharm Sci 110 (1) 239-250 [2021-01-00; online 2020-11-04]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Neuroimaging the menstrual cycle: A multimodal systematic review.
Dubol M, Epperson CN, Sacher J, ..., Sundström-Poromaa I, Comasco E
Front Neuroendocrinol 60 (-) 100878 [2021-01-00; online 2020-10-22]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality.
Stebbing J, Sánchez Nievas G, Falcone M, ..., Abizanda P, Lauschke VM
Sci Adv 7 (1) - [2021-01-00; online 2021-01-01]
Claudia Kutter SciLifeLab Fellow
DOI Crossref
Network Analyses Links Epicardial Fat Metabolism to Human Coronary Heart Disease
Doran S, Arif M, Clausen M, ..., Mardinoglu A, Boren J
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Multiomics Personalized Network Analyses Highlight Progressive Immune Disruption of Central Metabolism Associated with COVID-19 Severity
Ambikan AT, Yang H, Krishnan S, ..., Benfeitas R, Neogi U
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Molecular Imaging of Diabetes
Joosten L, Boss M, Jansen T, ..., de Galan B, Gotthardt M
- - (-) 1415-1431 [2021-00-00; online 2021-00-00]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Mitochondrial Metabolism Drives Triacylglycerol Synthesis to Control Regulatory T Cell Differentiation
Matias MI, Yong C, Foroushani A, ..., Dardalhon V, Taylor N
SSRN Journal - (-) - [2021-00-00; online 2021-00-00]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Genome-Scale Metabolic Modelling of the Human Gut Microbiome Reveals Changes of the Glyoxylate and Dicarboxylate Metabolism in Metabolic Disorders
Proffitt C, Bidkhori G, Lee S, ..., Moyes DL, Shoaie S
SSRN Journal - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Drug Repositioning for Clear Cell Renal Cell Carcinoma Based on Stratification of Patients
Li X, Kim W, Juszczak K, ..., Zhang C, Mardinoglu A
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Combined Metabolic Cofactor Supplementation Reduces Liver Fat in Nonalcoholic Fatty Liver Disease
Zeybel M, Altay O, Arif M, ..., Boren J, Mardinoglu A
SSRN Journal - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Combined Metabolic Activators Improves Cognitive Functions in Alzheimer's Disease
Yulug B, Altay O, Li X, ..., Uhlen M, Mardinoglu A
SSRN Journal - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Combined Metabolic Activators Decrease Liver Steatosis by Activating Mitochondrial Metabolism in a Golden Syrian Hamster Study
Yang H, Mayneris-Perxachs J, Boqué N, ..., Mardinoglu A, Caimari A
SSRN Journal - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Combined Metabolic Activators Decrease Liver Steatosis by Activating Mitochondrial Metabolism in a Golden Syrian Hamster Study
Yang H, Mayneris-Perxachs J, Boqué N, ..., Mardinoglu A, Caimari A
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Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
B Cell Expansion Hinders the Stroma-Epithelium Regenerative Crosstalk During Mucosal Healing
Frede A, Tripathi KP, Czarnewski P, ..., Saez-Rodriguez J, Villablanca EJ
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Camilla Engblom SciLifeLab Fellow
DOI Crossref
A Network-Based Approach Reveals the Dysregulated Transcriptional Regulation in Non- Alcohol Fatty Liver Disease
Yang H, Arif M, Yuan M, ..., Zhang C, Mardinoglu A
- - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow

Year 2020

DOI Crossref
Author response: Identification of ligand-specific G protein-coupled receptor states and prediction of downstream efficacy via data-driven modeling
Fleetwood O, Carlsson J, Delemotte L
- - (-) - [2020-12-23; online 2020-12-23]
Jens Carlsson Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.
Lehmann LC, Bacic L, Hewitt G, ..., Boulton SJ, Deindl S
Cell Reports 33 (12) 108529 [2020-12-22; online 2020-12-29]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
Aggregation and immobilisation of membrane proteins interplay with local lipid order in the plasma membrane of T cells
Urbančič I, Schiffelers L, Jenkins E, ..., Sezgin E, Eggeling C
- - (-) - [2020-12-22; online 2020-12-22]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
The chaperonin GroESL facilitates Caulobacter crescentus cell division by supporting the function of the actin homologue FtsA
Schroeder K, Heinrich K, Neuwirth I, Jonas K
- - (-) - [2020-12-18; online 2020-12-18]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Editorial: Redox Homeostasis and Cancer.
Sinha M, Mardinoglu A, Ghose J, Singh K
Oxid Med Cell Longev 2020 (-) 5487381 [2020-12-18; online 2020-12-18]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Informing NMR experiments with molecular dynamics simulations to characterize the dominant activated state of the KcsA ion channel
Pérez-Conesa S, Keeler EG, Zhang D, Delemotte L, McDermott AE
- - (-) - [2020-12-15; online 2020-12-15]
Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Plastic-degrading potential across the global microbiome correlates with recent pollution trends
Zrimec J, Kokina M, Jonasson S, Zorrilla F, Zelezniak A
- - (-) - [2020-12-13; online 2020-12-13]
Aleksej Zelezniak SciLifeLab Fellow
DOI Crossref
Three-dimensional spatial transcriptomics uncovers cell type dynamics in the rheumatoid arthritis synovium
Vickovic S, Schapiro D, Carlberg K, ..., Regev A, Ståhl PL
- - (-) - [2020-12-11; online 2020-12-11]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Parallel Factor Analysis Enables Quantification and Identification of Highly Convolved Data-Independent-Acquired Protein Spectra.
Buric F, Zrimec J, Zelezniak A
Patterns (N Y) 1 (9) 100137 [2020-12-11; online 2020-11-05]
Aleksej Zelezniak SciLifeLab Fellow
DOI Crossref
Functional crosstalk between phosphorylation and disease-causing mutations in the cardiac sodium channel Na v 1.5
Galleano I, Harms H, Choudhury K, ..., Delemotte L, Pless SA
- - (-) - [2020-12-11; online 2020-12-11]
Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Bridging the Gap Between Atomistic Molecular Dynamics Simulations and Wet-lab Experimental Techniques: Applications to Membrane Proteins
Delemotte L
- - (-) 247-286 [2020-12-10; online 2020-12-10]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Automated Removal of Non-homologous Sequence Stretches with PREQUAL.
Irisarri I, Burki F, Whelan S
Methods in molecular biology (Clifton, N.J.) 2231 (-) 147-162 [2020-12-09; online 2020-12-09]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development.
Malkani S, Chin CR, Cekanaviciute E, ..., Mason CE, Beheshti A
Cell Reports 33 (10) 108448 [2020-12-08; online 2020-11-25]
DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
DOI Crossref
NGSpeciesID: DNA barcode and amplicon consensus generation from long-read sequencing data
Sahlin K, Lim M, Prost S
- - (-) - [2020-12-04; online 2020-12-04]
Kristoffer Sahlin SciLifeLab Fellow
DOI Crossref
Guidelines for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samples
Kubik S, Marques AC, Xing X, ..., Willig A, Xu Z
- - (-) - [2020-12-01; online 2020-12-01]
SciLifeLab Fellow
PubMed DOI Crossref
Recent advances in single-molecule fluorescence microscopy render structural biology dynamic.
Bacic L, Sabantsev A, Deindl S
Curr. Opin. Struct. Biol. 65 (-) 61-68 [2020-12-00; online 2020-07-04]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Improved computational analysis of ribosome dynamics from 5'P degradome data using fivepseq.
Nersisyan L, Ropat M, Pelechano V
NAR Genomics and Bioinformatics 2 (4) lqaa099 [2020-12-00; online 2020-11-24]
SciLifeLab Fellow
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Genome-wide detection of DNA double-strand breaks by in-suspension BLISS.
Bouwman BAM, Agostini F, Garnerone S, ..., Roukos V, Crosetto N
Nat Protoc 15 (12) 3894-3941 [2020-12-00; online 2020-11-02]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening.
Kang PW, Westerlund AM, Shi J, ..., Delemotte L, Cui J
Sci Adv 6 (50) - [2020-12-00; online 2020-12-11]
Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Phenotypic plasticity, population structure and adaptation in a young weed species with a worldwide distribution
Cornille A, Tiret M, Salcedo A, ..., Wright SI, Lascoux M
- - (-) - [2020-11-28; online 2020-11-28]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Maturation of Monocyte-Derived DCs Leads to Increased Cellular Stiffness, Higher Membrane Fluidity, and Changed Lipid Composition.
Lühr JJ, Alex N, Amon L, ..., Guck J, Dudziak D
Front Immunol 11 (-) 590121 [2020-11-27; online 2020-11-27]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Universal Single-Residue Terminal Labels for Fluorescent Live Cell Imaging of Microproteins.
Lafranchi L, Schlesinger D, Kimler KJ, Elsässer SJ
Journal of the American Chemical Society 142 (47) 20080-20087 [2020-11-25; online 2020-11-11]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
Faculty Opinions recommendation of Genome-wide Nucleotide-Resolution Mapping of DNA Replication Patterns, Single-Strand Breaks, and Lesions by GLOE-Seq.
Elsässer S
- - (-) - [2020-11-25; online 2020-11-13]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Application of Cryo-EM for Visualization of Mitoribosomes.
Singh V, Amunts A
Methods in molecular biology (Clifton, N.J.) 2192 (-) 197-210 [2020-11-25; online 2020-11-25]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
The anti-inflammatory peptide Catestatin blocks chemotaxis
Muntjewerff EM, Parv K, Mahata SK, ..., Christoffersson G, van den Bogaart G
- - (-) - [2020-11-24; online 2020-11-24]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Comparative interactomes of HSF1 in stress and disease reveal a role for CTCF in HSF1-mediated gene regulation.
Burchfiel ET, Vihervaara A, Guertin MJ, Gomez-Pastor R, Thiele DJ
J Biol Chem 296 (-) 100097 [2020-11-24; online 2020-11-24]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells.
Zhan C, Bidkhori G, Schwarz H, ..., Rockberg J, Chotteau V
iScience 23 (11) 101653 [2020-11-20; online 2020-10-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Comparative dietary sulfated metabolome analysis reveals unknown metabolic interactions of the gut microbiome and the human host.
Correia MSP, Jain A, Alotaibi W, ..., Rodriguez-Mateos A, Globisch D
Free Radic. Biol. Med. 160 (-) 745-754 [2020-11-20; online 2020-09-11]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Amino Acid Modified RNA Bases as Building Blocks of an Early Earth RNA-Peptide World.
Nainytė M, Müller F, Ganazzoli G, ..., Globisch D, Carell T
Chemistry 26 (65) 14856-14860 [2020-11-20; online 2020-10-14]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Ligand design by targeting a binding site water.
Matricon P, Suresh RR, Gao ZG, ..., Jacobson KA, Carlsson J
Chem Sci 12 (3) 960-968 [2020-11-19; online 2020-11-19]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Lipoprotein Particles Interact with Membranes and Transfer Their Cargo without Receptors.
Plochberger B, Sych T, Weber F, ..., Stangl H, Sezgin E
Biochemistry 59 (45) 4421-4428 [2020-11-17; online 2020-11-04]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Comprehensive dataset of shotgun metagenomes from stratified freshwater lakes and ponds
Buck M, Garcia SL, Vidal LF, ..., Bertilsson S, Peura S
- - (-) - [2020-11-12; online 2020-11-12]
Sarahi Garcia Sari Peura SciLifeLab Fellow
DOI Crossref
Point-of-care detection of SARS-CoV-2 in nasopharyngeal swab samples using an integrated smartphone-based centrifugal microfluidic platform
Soares RRG, Akhtar AS, Pinto IF, ..., Pelechano V, Russom A
- - (-) - [2020-11-06; online 2020-11-06]
SciLifeLab Fellow
PubMed DOI Crossref
Redesigning Solvatochromic Probe Laurdan for Imaging Lipid Order Selectively in Cell Plasma Membranes.
Danylchuk DI, Sezgin E, Chabert P, Klymchenko AS
Anal. Chem. 92 (21) 14798-14805 [2020-11-03; online 2020-10-12]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Computational Analysis of Alzheimer Amyloid Plaque Composition in 2D- and Elastically Reconstructed 3D-MALDI MS Images.
Enzlein T, Cordes J, Munteanu B, ..., Chávez-Gutiérrez L, Hopf C
Anal. Chem. 92 (21) 14484-14493 [2020-11-03; online 2020-10-14]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Tracking the motion of the KV1.2 voltage sensor reveals the molecular perturbations caused by a de novo mutation in a case of epilepsy.
Pantazis A, Kaneko M, Angelini M, ..., Saitta SC, Olcese R
J. Physiol. (Lond.) 598 (22) 5245-5269 [2020-11-00; online 2020-09-21]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Quantification of aromatase binding in the female human brain using [11 C]cetrozole positron emission tomography.
Jonasson M, Nordeman P, Eriksson J, ..., Lubberink M, Comasco E
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Disease, Drugs and Dysbiosis: Understanding Microbial Signatures in Metabolic Disease and Medical Interventions.
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Endocrinol Metab (Seoul) 35 (3) 507-514 [2020-09-00; online 2020-09-22]
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Jonas Barandun SciLifeLab Fellow
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Daniel Globisch SciLifeLab Fellow
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Super-resolution RESOLFT microscopy of lipid bilayers using a fluorophore-switch dyad.
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Phylogenomic Insights into the Origin of Primary Plastids
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Fabien Burki SciLifeLab Fellow
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Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution.
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The cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) targets the olfactory bulb region.
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Jens Carlsson SciLifeLab Fellow
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Mol. Phylogenet. Evol. 149 (-) 106839 [2020-08-00; online 2020-04-21]
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Neuroprotective effects of boron nitride nanoparticles in the experimental Parkinson's disease model against MPP+ induced apoptosis.
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Adil Mardinoglu SciLifeLab Fellow
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Gustaf Christoffersson SciLifeLab Fellow
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Jens Carlsson SciLifeLab Fellow
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Natoli M, Bonito N, Robinson JD, Ghaem-Maghami S, Mao Y
Cancer Immunol. Immunother. 69 (8) 1403-1408 [2020-08-00; online 2020-06-20]
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Archaea in boreal Swedish lakes are diverse, dominated by Woesearchaeota and follow deterministic community assembly.
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Ilaria Testa SciLifeLab Fellow
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Automated GMP-Compliant Production of [68Ga]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans.
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Current Status of COVID-19 Therapies and Drug Repositioning Applications.
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Spatial Deconvolution of HER2-positive Breast Tumors Reveals Novel Intercellular Relationships
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Systems Biology Approaches to Understand the Host-Microbiome Interactions in Neurodegenerative Diseases.
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Pulsed Electric Fields Can Create Pores in the Voltage Sensors of Voltage-Gated Ion Channels.
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Network analysis reveals how lipids and other cofactors influence membrane protein allostery
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Lucie Delemotte SciLifeLab Fellow
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Identification of ligand-specific G-protein coupled receptor states and prediction of downstream efficacy via data-driven modeling
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Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening
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Lucie Delemotte SciLifeLab Fellow
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A translational multiplex serology approach to profile the prevalence of anti-SARS-CoV-2 antibodies in home-sampled blood
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Rapid Detection of COVID-19 Coronavirus Using a Reverse Transcriptional Loop-Mediated Isothermal Amplification (RT-LAMP) Diagnostic Platform.
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Mechanism and effects of the skeletal muscle Nav1.4 inhibition by cannabidiol
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Lucie Delemotte SciLifeLab Fellow
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EukProt: A database of genome-scale predicted proteins across the diversity of eukaryotes
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Fabien Burki SciLifeLab Fellow
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Diazotroph Genomes and Their Seasonal Dynamics in a Stratified Humic Bog Lake.
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Quo vadis microRNAs?
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Marc Friedländer SciLifeLab Fellow
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Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation.
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PLoS Pathog 16 (7) e1008656 [2020-07-00; online 2020-07-08]
Erdinc Sezgin SciLifeLab Fellow
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DNA surface exploration and operator bypassing during target search.
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Daniel Globisch Emil Marklund SciLifeLab Fellow Sebastian Deindl
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A systems biology approach for studying neurodegenerative diseases.
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Alexey Amunts SciLifeLab Fellow
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Skeletal Muscle Transcriptomic Comparison between Long-Term Trained and Untrained Men and Women.
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Cell Reports 31 (12) 107808 [2020-06-23; online 2020-06-25]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Site-Specific Incorporation of Two ncAAs for Two-Color Bioorthogonal Labeling and Crosslinking of Proteins on Live Mammalian Cells.
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Cell Reports 31 (12) 107811 [2020-06-23; online 2020-06-25]
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High-throughput 5’P sequencing enables the study of degradation-associated ribosome stalls
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Successful delivery of large-size CRISPR/Cas9 vectors in hard-to-transfect human cells using small plasmids.
Søndergaard JN, Geng K, Sommerauer C, ..., Yin X, Kutter C
Commun Biol 3 (1) 319 [2020-06-19; online 2020-06-19]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Adipose tissue morphology, imaging and metabolomics predicting cardiometabolic risk and family history of type 2 diabetes in non-obese men.
Rawshani A, Eliasson B, Rawshani A, ..., Rosengren A, Smith U
Sci Rep 10 (1) 9973 [2020-06-19; online 2020-06-19]
Adil Mardinoglu SciLifeLab Fellow
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Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation.
Tobiasson V, Amunts A
Elife 9 (-) e59264 [2020-06-18; online 2020-06-18]
Alexey Amunts SciLifeLab Fellow
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Resin-acid derivatives bind to multiple sites on the voltage-sensor domain of the Saker channel
Silverå Ejneby M, Gromova A, Ottosson NE, ..., Elinder F, Delemotte L
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Lucie Delemotte SciLifeLab Fellow
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Influence of nanobody binding on fluorescence emission, mobility and organization of GFP-tagged proteins
Schneider F, Eggeling C, Sezgin E
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Erdinc Sezgin SciLifeLab Fellow
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Distinct pre-initiation steps in human mitochondrial translation.
Khawaja A, Itoh Y, Remes C, ..., Amunts A, Rorbach J
Nat Commun 11 (1) 2932 [2020-06-10; online 2020-06-10]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Chaining with Overlaps Revisited
Sahlin K, Mäkinen V
31st Annual Symposium on Combinatorial Pattern Matching (CPM 2020) 161 (-) 25:1--25:12 [2020-06-09; online 2020-06-09]
Kristoffer Sahlin SciLifeLab Fellow
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Author response: Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation
Tobiasson V, Amunts A
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Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Sensitive mass spectrometric analysis of carbonyl metabolites in human urine and fecal samples using chemoselective modification.
Lin W, Conway LP, Block A, ..., Löhr JM, Globisch D
Analyst 145 (11) 3822-3831 [2020-06-07; online 2020-05-12]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape.
Lorent JH, Levental KR, Ganesan L, ..., Lyman E, Levental I
Nat. Chem. Biol. 16 (6) 644-652 [2020-06-00; online 2020-05-04]
DDLS Fellow Erdinc Sezgin Milka Doktorova SciLifeLab Fellow
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Improvement in the Current Therapies for Hepatocellular Carcinoma Using a Systems Medicine Approach.
Ozcan M, Altay O, Lam S, ..., Boren J, Mardinoglu A
Adv Biosyst 4 (6) e2000030 [2020-06-00; online 2020-04-08]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Germ-free and microbiota-associated mice yield small intestinal epithelial organoids with equivalent and robust transcriptome/proteome expression phenotypes.
Hausmann A, Russo G, Grossmann J, ..., Sellin ME, Hardt WD
Cell. Microbiol. 22 (6) e13191 [2020-06-00; online 2020-03-04]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Dose and time effects of solar-simulated ultraviolet radiation on the in vivo human skin transcriptome.
Bustamante M, Hernandez-Ferrer C, Tewari A, ..., Nieuwenhuijsen M, Young AR
Br. J. Dermatol. 182 (6) 1458-1468 [2020-06-00; online 2019-11-27]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Author Correction: Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape.
Lorent JH, Levental KR, Ganesan L, ..., Lyman E, Levental I
Nat. Chem. Biol. 16 (6) 710 [2020-06-00; online 2020-05-18]
DDLS Fellow Erdinc Sezgin Milka Doktorova SciLifeLab Fellow
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Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media.
Teleki A, Nylander O, Bergström CAS
Pharmaceutics 12 (6) 493 [2020-05-28; online 2020-05-28]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Shift in ecological strategy helps marginal populations of shepherd's purse (Capsella bursa-pastoris) to overcome a high genetic load.
Orsucci M, Milesi P, Hansen J, ..., Glémin S, Lascoux M
Proc. Biol. Sci. 287 (1927) 20200463 [2020-05-27; online 2020-05-20]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
Sirtuin-1 Sensitive Lysine-136 Acetylation Drives Phase Separation and Pathological Aggregation of TDP-43
Morato JG, Hans F, von Zweydorf F, ..., Neumann M, Kahle PJ
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SciLifeLab Fellow Simon Elsässer
DOI Crossref
GPSeq reveals the radial organization of chromatin in the cell nucleus
Custodio J, Kallas T, Girelli G, ..., Crosetto N, Bienko M
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Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis.
Thomas QA, Ard R, Liu J, ..., Pelechano V, Marquardt S
Nat Commun 11 (1) 2589 [2020-05-22; online 2020-05-22]
SciLifeLab Fellow
DOI Crossref
An embryonic stem cell-specific heterochromatin state allows core histone exchange in the absence of DNA accessibility
Navarro C, Elsässer SJ
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SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Integrating the "Immunome" in the Stratification of Myelodysplastic Syndromes and Future Clinical Trial Design.
Winter S, Shoaie S, Kordasti S, Platzbecker U
J Clin Oncol 38 (15) 1723-1735 [2020-05-20; online 2020-02-14]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
z-STED Imaging and Spectroscopy to Investigate Nanoscale Membrane Structure and Dynamics.
Barbotin A, Urbančič I, Galiani S, ..., Booth M, Sezgin E
Biophys. J. 118 (10) 2448-2457 [2020-05-19; online 2020-04-16]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Histidyl-Proline Diketopiperazine Isomers as Multipotent Anti-Alzheimer Drug Candidates.
Turkez H, Cacciatore I, Arslan ME, ..., Di Stefano A, Mardinoglu A
Biomolecules 10 (5) 737 [2020-05-09; online 2020-05-09]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Predicting resolution and image quality in RESOLFT and other point scanning microscopes [Invited].
Bodén A, Casas Moreno X, Cooper BK, York AG, Testa I
Biomed Opt Express 11 (5) 2313-2327 [2020-05-01; online 2020-04-02]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Differential Expression of Immune Genes between Two Closely Related Beetle Species with Different Immunocompetence following Attack by Asecodes parviclava.
Yang X, Fors L, Slotte T, ..., Wheat CW, Hambäck PA
Genome Biol Evol 12 (5) 522-534 [2020-05-01; online 2020-04-14]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium.
Fattinger SA, Böck D, Di Martino ML, ..., Hardt WD, Sellin ME
PLoS Pathog 16 (5) e1008503 [2020-05-00; online 2020-05-04]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression.
Hausmann A, Böck D, Geiser P, ..., Sellin ME, Hardt WD
Mucosal Immunol 13 (3) 530-544 [2020-05-00; online 2020-01-17]
Mikael Sellin SciLifeLab Fellow
DOI Crossref
Bistability in oxidative stress response determines the migration behavior of phytoplankton in turbulence
Carrara F, Sengupta A, Behrendt L, Vardi A, Stocker R
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Lars Behrendt SciLifeLab Fellow
DOI Crossref
Parallel factor analysis enables quantification and identification of highly-convolved data independent-acquired protein spectra
Buric F, Zrimec J, Zelezniak A
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Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development.
Larsson I, Uhlén M, Zhang C, Mardinoglu A
Front Genet 11 (-) 381 [2020-04-17; online 2020-04-17]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
High photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopy.
Schneider F, Hernandez-Varas P, Christoffer Lagerholm B, ..., Eggeling C, Urbančič I
J. Phys. D: Appl. Phys. 53 (16) 164003 [2020-04-15; online 2020-02-13]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
The European Research Network on Signal Transduction (ERNEST): Toward a Multidimensional Holistic Understanding of G Protein-Coupled Receptor Signaling.
Sommer ME, Selent J, Carlsson J, ..., Waldhoer M, Kolb P
ACS pharmacology & translational science 3 (2) 361-370 [2020-04-10; online 2020-03-31]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
The in vitro cytotoxic, genotoxic, and oxidative damage potentials of the oral artificial sweetener aspartame on cultured human blood cells.
Çadirci K, Özdemir Tozlu Ö, Türkez H, Mardinoğlu A
Turk J Med Sci 50 (2) 448-454 [2020-04-09; online 2020-04-09]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Pooled CRISPRi screening of the cyanobacterium Synechocystis sp PCC 6803 for enhanced industrial phenotypes.
Yao L, Shabestary K, Björk SM, ..., Jahn M, Hudson EP
Nat Commun 11 (1) 1666 [2020-04-03; online 2020-04-03]
Paul Hudson SciLifeLab Fellow
DOI Crossref
Bayesian genome scale modelling identifies thermal determinants of yeast metabolism
Li G, Hu Y, Wang H, ..., Zrimec J, Nielsen J
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Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
Tumour heterogeneity and the evolutionary trade-offs of cancer.
Hausser J, Alon U
Nat. Rev. Cancer 20 (4) 247-257 [2020-04-00; online 2020-02-24]
Jean Hausser SciLifeLab Fellow
PubMed DOI Crossref
The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease.
Zhang C, Bjornson E, Arif M, ..., Borén J, Mardinoglu A
Mol Syst Biol 16 (4) e9495 [2020-04-00; online 2020-04-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Publisher Correction: MEMOTE for standardized genome-scale metabolic model testing.
Lieven C, Beber ME, Olivier BG, ..., Zakhartsev M, Zhang C
Nat. Biotechnol. 38 (4) 504 [2020-04-00; online 2020-04-09]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Investigation of the demetallation of 10-aryl substituted synthetic chlorins under acidic conditions.
Arkhypchuk AI, Xiong R, Borbas KE
J Inorg Biochem 205 (-) 110979 [2020-04-00; online 2020-01-03]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
De Novo Clustering of Long-Read Transcriptome Data Using a Greedy, Quality Value-Based Algorithm.
Sahlin K, Medvedev P
J. Comput. Biol. 27 (4) 472-484 [2020-04-00; online 2020-03-16]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Application of unsupervised learning and process simulation for energy optimization of a WWTP under various weather conditions.
Borzooei S, Miranda GHB, Abolfathi S, ..., Meucci L, Zanetti MC
Water Sci Technol 81 (8) 1541-1551 [2020-04-00; online 2020-07-10]
Gisele Miranda SciLifeLab Fellow
PubMed DOI Crossref
An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models.
Choi MJ, Jung SB, Lee SE, ..., Yi HS, Shong M
Diabetologia 63 (4) 837-852 [2020-04-00; online 2020-01-10]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives
Bohutínská M, Vlček J, Yair S, ..., Slotte T, Kolář F
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SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
An atlas of human metabolism.
Robinson JL, Kocabaş P, Wang H, ..., Uhlén M, Nielsen J
Sci Signal 13 (624) eaaz1482 [2020-03-24; online 2020-03-24]
Adil Mardinoglu Avlant Nilsson DDLS Fellow SciLifeLab Fellow
DOI Crossref
Streamlined freshwater bacterioplankton Nanopelagicales (acI) and “ Ca . Fonsibacter” (LD12) thrive in functional cohorts
Mondav R, Bertilsson S, Buck M, ..., Lindström ES, Garcia SL
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Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Monoamine oxidase A genotype and methylation moderate the association of maltreatment and aggressive behaviour.
Checknita D, Bendre M, Ekström TJ, ..., Hodgins S, Nilsson KW
Behav. Brain Res. 382 (-) 112476 [2020-03-16; online 2020-01-10]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
An atlas of the protein-coding genes in the human, pig, and mouse brain.
Sjöstedt E, Zhong W, Fagerberg L, ..., Uhlén M, Mulder J
Science (New York, N.Y.) 367 (6482) eaay5947 [2020-03-06; online 2020-03-07]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Structure of a minimal photosystem I from the green alga Dunaliella salina.
Perez-Boerema A, Klaiman D, Caspy I, ..., Amunts A, Nelson N
Nat Plants 6 (3) 321-327 [2020-03-00; online 2020-03-02]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Performance of virtual screening against GPCR homology models: Impact of template selection and treatment of binding site plasticity.
Jaiteh M, Rodríguez-Espigares I, Selent J, Carlsson J
PLoS Comput Biol 16 (3) e1007680 [2020-03-00; online 2020-03-13]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
MEMOTE for standardized genome-scale metabolic model testing.
Lieven C, Beber ME, Olivier BG, ..., Zakhartsev M, Zhang C
Nat. Biotechnol. 38 (3) 272-276 [2020-03-00; online 2020-03-04]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Long-read metabarcoding of the eukaryotic rDNA operon to phylogenetically and taxonomically resolve environmental diversity.
Jamy M, Foster R, Barbera P, ..., Bass D, Burki F
Mol Ecol Resour 20 (2) 429-443 [2020-03-00; online 2019-11-29]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Life in the dark: far-red absorbing cyanobacteria extend photic zones deep into terrestrial caves.
Behrendt L, Trampe EL, Nord NB, ..., Hershey OS, Barton H
Environ. Microbiol. 22 (3) 952-963 [2020-03-00; online 2019-09-09]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Distinct structural modulation of photosystem I and lipid environment stabilizes its tetrameric assembly.
Chen M, Perez-Boerema A, Zhang L, ..., Li S, Amunts A
Nat Plants 6 (3) 314-320 [2020-03-00; online 2020-03-09]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Chemical imaging of evolving amyloid plaque pathology and associated Aβ peptide aggregation in a transgenic mouse model of Alzheimer's disease.
Michno W, Wehrli P, Meier SR, ..., Blennow K, Hanrieder J
J. Neurochem. 152 (5) 602-616 [2020-03-00; online 2019-11-06]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Impact of Nanoscale Hindrances on the Relationship between Lipid Packing and Diffusion in Model Membranes.
Beckers D, Urbancic D, Sezgin E
J Phys Chem B 124 (8) 1487-1494 [2020-02-27; online 2020-02-18]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma.
Das Mahapatra K, Pasquali L, Søndergaard JN, ..., Kristensen LS, Pivarcsi A
Sci Rep 10 (1) 3637 [2020-02-27; online 2020-02-27]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Energy Landscapes Reveal Agonist Control of G Protein-Coupled Receptor Activation via Microswitches.
Fleetwood O, Matricon P, Carlsson J, Delemotte L
Biochemistry 59 (7) 880-891 [2020-02-25; online 2020-02-07]
Jens Carlsson Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Rapid colorimetric detection of COVID-19 coronavirus using a reverse transcriptional loop-mediated isothermal amplification (RT-LAMP) diagnostic platform: iLACO
Yu L, Wu S, Hao X, ..., Chen WH, Yin X
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SciLifeLab Fellow
PubMed DOI Crossref
Creating Supported Plasma Membrane Bilayers Using Acoustic Pressure.
Sezgin E, Carugo D, Levental I, Stride E, Eggeling C
Membranes (Basel) 10 (2) 30 [2020-02-18; online 2020-02-18]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Biophysical Characterization of Epigallocatechin-3-Gallate Effect on the Cardiac Sodium Channel Nav1.5.
Amarouch MY, Kurt H, Delemotte L, Abriel H
Molecules 25 (4) 902 [2020-02-18; online 2020-02-18]
Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Live cell imaging reveals that RecA finds homologous DNA by reduced dimensionality search
Wiktor J, Gynnå AH, Leroy P, ..., Testa I, Elf J
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Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Radial Organization in the Mammalian Nucleus.
Crosetto N, Bienko M
Front Genet 11 (-) 33 [2020-02-12; online 2020-02-12]
Magda Bienko SciLifeLab Fellow
DOI Crossref
Predatory colponemids are the sister group to all other alveolates
Tikhonenkov DV, Strassert JFH, Janouškovec J, ..., Burki F, Keeling PJ
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Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Regulation of lipid saturation without sensing membrane fluidity.
Ballweg S, Sezgin E, Doktorova M, ..., Hummer G, Ernst R
Nat Commun 11 (1) 756 [2020-02-06; online 2020-02-06]
DDLS Fellow Erdinc Sezgin Milka Doktorova SciLifeLab Fellow
PubMed DOI Crossref
Molecular Insights from Conformational Ensembles via Machine Learning.
Fleetwood O, Kasimova MA, Westerlund AM, Delemotte L
Biophys. J. 118 (3) 765-780 [2020-02-04; online 2019-12-21]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Abundance and diversity of resistomes differ between healthy human oral cavities and gut.
Carr VR, Witherden EA, Lee S, ..., Gomez-Cabrero D, Moyes DL
Nat Commun 11 (1) 693 [2020-02-04; online 2020-02-04]
Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM, Amunts A
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Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API.
Desvignes T, Loher P, Eilbeck K, ..., Halushka MK, Pantano L
Bioinformatics 36 (3) 698-703 [2020-02-01; online 2019-09-11]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
The molecular basis for sugar import in malaria parasites.
Qureshi AA, Suades A, Matsuoka R, ..., Delemotte L, Drew D
Nature 578 (7794) 321-325 [2020-02-00; online 2020-01-29]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Handling ties in continuous outcomes for confounder adjustment with rank-ordered logit and its application to ordinal outcomes.
Ning Y, Tan CS, Maraki A, ..., Reilly M, Støer NC
Stat Methods Med Res 29 (2) 437-454 [2020-02-00; online 2019-04-03]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Environmental impacts and limitations of third‐generation biobutanol: Life cycle assessment of ‐butanol produced by genetically engineered cyanobacteria
Nilsson A, Shabestary K, Brandão M, Hudson EP
Journal of Industrial Ecology 24 (1) 205-216 [2020-02-00; online 2019-04-00]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Classification of clear cell renal cell carcinoma based on PKM alternative splicing.
Li X, Turanli B, Juszczak K, ..., Zhang C, Mardinoglu A
Heliyon 6 (2) e03440 [2020-02-00; online 2020-02-19]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Calmodulin Functionally Couples the KCNQ1 Channel Voltage-Sensing and Pore Domains
Kang PW, Westerlund AM, Shi J, ..., Delemotte L, Cui J
Biophysical Journal 118 (3) 332a-333a [2020-02-00; online 2020-02-00]
Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Mechanism of DNA surface exploration and operator bypassing during target search
Marklund E, van Oosten B, Mao G, ..., Elf J, Deindl S
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Daniel Globisch SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D.
Sayitoglu EC, Georgoudaki AM, Chrobok M, ..., Sutlu T, Duru AD
Front Immunol 11 (-) 40 [2020-01-28; online 2020-01-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Population Genomics of Transitions to Selfing in Brassicaceae Model Systems.
Mattila TM, Laenen B, Slotte T
Methods in molecular biology (Clifton, N.J.) 2090 (-) 269-287 [2020-01-25; online 2020-01-25]
SciLifeLab Fellow Tanja Slotte
DOI Crossref
Improved computational analysis of ribosome dynamics from 5’P degradome data using fivepeseq
Nersisyan L, Ropat M, Pelechano V
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SciLifeLab Fellow
PubMed DOI Crossref
Docking Finds GPCR Ligands in Dark Chemical Matter.
Ballante F, Rudling A, Zeifman A, ..., Loza MI, Carlsson J
J Med Chem 63 (2) 613-620 [2020-01-23; online 2020-01-13]
Andreas Luttens DDLS Fellow Jens Carlsson SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structure and activation mechanism of the BBSome membrane protein trafficking complex.
Amunts A
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Alexey Amunts SciLifeLab Fellow
DOI Crossref
Creating supported plasma membrane bilayers using acoustic pressure
Sezgin E, Carugo D, Levental I, Stride E, Eggeling C
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Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Impact of nanoscale hindrances on the relationship between lipid packing and diffusion in model membranes
Beckers D, Urbancic D, Sezgin E
- - (-) - [2020-01-16; online 2020-01-16]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation.
Pagoni A, Marinelli L, Di Stefano A, ..., Vassiliou S, Cacciatore I
Eur J Med Chem 186 (-) 111880 [2020-01-15; online 2019-11-12]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
A set of monomeric near-infrared fluorescent proteins for multicolor imaging across scales.
Matlashov ME, Shcherbakova DM, Alvelid J, ..., Testa I, Verkhusha VV
Nat Commun 11 (1) 239 [2020-01-13; online 2020-01-13]
Ilaria Testa SciLifeLab Fellow
DOI Crossref
Three dimensional parallelized RESOLFT nanoscopy for volumetric live cell imaging
Bodén A, Pennacchietti F, Testa I
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Ilaria Testa SciLifeLab Fellow
DOI Crossref
Stable stimulated emission depletion imaging of extended sample regions
Alvelid J, Testa I
J. Phys. D: Appl. Phys. 53 (2) 024001 [2020-01-09; online 2019-10-25]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
MirGeneDB 2.0: the metazoan microRNA complement.
Fromm B, Domanska D, Høye E, ..., Friedländer MR, Peterson KJ
Nucleic Acids Res. 48 (D1) D1172 [2020-01-08; online 2019-10-24]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
MirGeneDB 2.0: the metazoan microRNA complement.
Fromm B, Domanska D, Høye E, ..., Friedländer MR, Peterson KJ
Nucleic Acids Res. 48 (D1) D132-D141 [2020-01-08; online 2019-10-11]
Marc Friedländer SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system.
Amunts A
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Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent.
Amunts A
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Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of In Situ Structure of an Intact Lipopolysaccharide-Bound Bacterial Surface Layer.
Amunts A
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Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B.
Amunts A
- - (-) - [2020-01-02; online 2019-12-25]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Analysis of the Human Protein Atlas Image Classification competition.
Amunts A
- - (-) - [2020-01-02; online 2019-12-25]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of A mitochondrial megachannel resides in monomeric F1FO ATP synthase.
Amunts A
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Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Protein aggregation in bacteria.
Schramm FD, Schroeder K, Jonas K
FEMS Microbiol Rev 44 (1) 54-72 [2020-01-01; online 2019-10-22]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Advances in GLP-1 receptor targeting radiolabeled agent development and prospective of theranostics.
Velikyan I, Eriksson O
Theranostics 10 (1) 437-461 [2020-01-01; online 2020-01-01]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
The New Tree of Eukaryotes.
Burki F, Roger AJ, Brown MW, Simpson AGB
Trends in Ecology & Evolution 35 (1) 43-55 [2020-01-00; online 2019-10-09]
Fabien Burki SciLifeLab Fellow
DOI Crossref
Ontogenic succession of thermokarst thaw ponds is linked to dissolved organic matter quality and microbial degradation potential
Peura S, Wauthy M, Simone D, ..., Rautio M, Bertilsson S
Limnol. Oceanogr. 65 (S1) - [2020-01-00; online 2019-10-28]
Sari Peura SciLifeLab Fellow
DOI Crossref
Non‐cyanobacterial diazotrophs dominate nitrogen‐fixing communities in permafrost thaw ponds
Fernandez L, Bertilsson S, Peura S
Limnol. Oceanogr. 65 (S1) - [2020-01-00; online 2019-08-05]
Sari Peura SciLifeLab Fellow
DOI Crossref
Discovery of Functional Alternatively Spliced <i>PKM</i> Transcripts in Human Cancers
Li X, Zhang C, Kim W, ..., Uhlen M, Mardinoglu A
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Circulating miRNA Signature Predicts and Rescues Spaceflight Associated Health Risks
Malkani S, Cekanaviciute E, Mortreux M, ..., Grabham P, Beheshti A
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DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
DOI Crossref
Acute Kidney Injury Leading to CKD is Associated with a Persistence of Metabolic Dysfunction and Hypertriglyceridemia
Harzandi A, Bidkhori G, Lee S, ..., Shoaie S, Sharpe C
SSRN Journal - (-) - [2020-00-00; online 2020-00-00]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

Year 2019

DOI Crossref
z-STED imaging and spectroscopy to investigate nanoscale membrane structure and dynamics
Barbotin A, Urbančič I, Galiani S, ..., Booth M, Sezgin E
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Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Biophysical characterization of Epigallocatechin-3-Gallate effect on the cardiac sodium channel Nav1.5
AMAROUCH MY, Kurt MH, Delemotte L, Abriel H
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Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells.
Uhlen M, Karlsson MJ, Zhong W, ..., Fagerberg L, Brodin P
Science (New York, N.Y.) 366 (6472) eaax9198 [2019-12-20; online 2019-12-21]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
High genetic diversity but no geographical structure of Aedes albopictus populations in Réunion Island.
Latreille AC, Milesi P, Magalon H, Mavingui P, Atyame CM
Parasit Vectors 12 (1) 597 [2019-12-19; online 2019-12-19]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
Ancient microRNA profiles of a 14,300-year-old canid are taxonomically informative and give glimpses into gene regulation from the Pleistocene
Fromm B, Tarbier M, Smith O, ..., Gilbert MTP, Friedländer MR
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DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
DOI Crossref
Informing Pharmacokinetic Models with Physiological Data: Oral Population Modeling of L-Serine in Humans
Bosley JR, Björnson E, Zhang C, ..., Boren J, Mardinoglu A
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Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Oral Microbiota Development in Early Childhood.
Kennedy B, Peura S, Hammar U, ..., Bertilsson S, Fall T
Sci Rep 9 (1) 19025 [2019-12-13; online 2019-12-13]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart.
Asp M, Giacomello S, Larsson L, ..., Sylvén C, Lundeberg J
Cell 179 (7) 1647-1660.e19 [2019-12-12; online 2019-12-14]
Daniel Fürth Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
InfleCS: Clustering Free Energy Landscapes with Gaussian Mixtures.
Westerlund AM, Delemotte L
J Chem Theory Comput 15 (12) 6752-6759 [2019-12-10; online 2019-11-07]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Overeating Saturated Fat Promotes Fatty Liver and Ceramides Compared With Polyunsaturated Fat: A Randomized Trial.
Rosqvist F, Kullberg J, Ståhlman M, ..., Ahlström H, Risérus U
J. Clin. Endocrinol. Metab. 104 (12) 6207-6219 [2019-12-01; online 2019-08-02]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Nascent RNA analyses: tracking transcription and its regulation.
Wissink EM, Vihervaara A, Tippens ND, Lis JT
Nat. Rev. Genet. 20 (12) 705-723 [2019-12-00; online 2019-08-09]
Anniina Vihervaara SciLifeLab Fellow
DOI Crossref
Fluorescence microscopy at the molecular scale
Alvelid J, Testa I
Current Opinion in Biomedical Engineering 12 (-) 34-42 [2019-12-00; online 2019-12-00]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.
Wei W, Hennig BP, Wang J, ..., Steinmetz LM, Pelechano V
Genome Res 29 (12) 1974-1984 [2019-12-00; online 2019-11-18]
SciLifeLab Fellow
PubMed DOI Crossref
Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.
Klevstig M, Arif M, Mannila M, ..., Ehrenborg E, Borén J
J. Mol. Cell. Cardiol. 137 (-) 1-8 [2019-12-00; online 2019-09-15]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Assessing the potential for assisted gene flow using past introduction of Norway spruce in southern Sweden: Local adaptation and genetic basis of quantitative traits in trees.
Milesi P, Berlin M, Chen J, ..., Karlsson B, Lascoux M
Evol Appl 12 (10) 1946-1959 [2019-12-00; online 2019-08-22]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
Dissecting chronic myeloid leukaemia overlapping transcriptome with TIF-Seq2
Wang J, Li B, Marques S, ..., Wei W, Pelechano V
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SciLifeLab Fellow
DOI Crossref
The SWI/SNF subunits BRG1 affects alternative splicing by changing RNA binding factor interactions with RNA
Zapater AG, Mackowiak SD, Guo Y, ..., Visa N, Farrants AKÖ
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Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Helix breaking transition in the S4 of HCN channel is critical for hyperpolarization-dependent gating.
Kasimova MA, Tewari D, Cowgill JB, ..., Delemotte L, Chanda B
Elife 8 (-) - [2019-11-27; online 2019-11-27]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
The human secretome.
Uhlén M, Karlsson MJ, Hober A, ..., Fagerberg L, Sivertsson Å
Sci Signal 12 (609) eaaz0274 [2019-11-26; online 2019-11-26]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Evolutionary Refinement of DNA Nanostructures Using Coarse-Grained Molecular Dynamics Simulations.
Benson E, Lolaico M, Tarasov Y, Gådin A, Högberg B
ACS Nano 13 (11) 12591-12598 [2019-11-26; online 2019-10-15]
Erik Benson SciLifeLab Fellow
PubMed DOI Crossref
Metabolically Active Brown Adipose Tissue Is Found in Adult Subjects with Type 1 Diabetes.
Eriksson O, Selvaraju RK, Berglund M, Espes D
Int J Mol Sci 20 (23) 5827 [2019-11-20; online 2019-11-20]
Daniel Espes Olof Eriksson SciLifeLab Fellow
DOI Crossref
Author response: Helix breaking transition in the S4 of HCN channel is critical for hyperpolarization-dependent gating
Kasimova MA, Tewari D, Cowgill JB, ..., Delemotte L, Chanda B
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Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Structure of a mitochondrial ATP synthase with bound native cardiolipin.
Mühleip A, McComas SE, Amunts A
Elife 8 (-) - [2019-11-18; online 2019-11-18]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
More Favorable Palmitic Acid Over Palmitoleic Acid Modification of Wnt3 Ensures Its Localization and Activity in Plasma Membrane Domains.
Azbazdar Y, Ozalp O, Sezgin E, ..., Karaca E, Ozhan G
Front Cell Dev Biol 7 (-) 281 [2019-11-15; online 2019-11-15]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
GPCRmd uncovers the dynamics of the 3D-GPCRome
Rodríguez-Espigares I, Torrens-Fontanals M, Tiemann JKS, ..., Guixà-González R, Selent J
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Jens Carlsson SciLifeLab Fellow
DOI Crossref
Classification of clear cell renal cell carcinoma based on PKM alternative splicing
Li X, Turanli B, Juszczak K, ..., Zhang C, Mardinoglu A
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Author response: Structure of a mitochondrial ATP synthase with bound native cardiolipin
Mühleip A, McComas SE, Amunts A
- - (-) - [2019-11-12; online 2019-11-12]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Systems biology perspective for studying the gut microbiota in human physiology and liver diseases.
Altay O, Nielsen J, Uhlen M, Boren J, Mardinoglu A
EBioMedicine 49 (-) 364-373 [2019-11-00; online 2019-10-18]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Molecular imaging mass spectrometry for probing protein dynamics in neurodegenerative disease pathology.
Michno W, Wehrli PM, Blennow K, Zetterberg H, Hanrieder J
J. Neurochem. 151 (4) 488-506 [2019-11-00; online 2018-11-06]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome.
Barandun J, Hunziker M, Vossbrinck CR, Klinge S
Nat. Microbiol 4 (11) 1798-1804 [2019-11-00; online 2019-07-22]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Chemometric Strategies for Sensitive Annotation and Validation of Anatomical Regions of Interest in Complex Imaging Mass Spectrometry Data.
Wehrli PM, Michno W, Blennow K, Zetterberg H, Hanrieder J
J. Am. Soc. Mass Spectrom. 30 (11) 2278-2288 [2019-11-00; online 2019-09-16]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Association of PTHrP levels in CSF with Alzheimer's disease biomarkers.
Kushnir MM, Michno W, Rockwood AL, ..., Strathmann FG, Hanrieder J
Clin Mass Spectrom 14 Pt B (-) 124-129 [2019-11-00; online 2018-10-09]
SciLifeLab Fellow Wojciech Michno
DOI Crossref
Pooled CRISPRi screening of the cyanobacterium Synechocystis sp. PCC 6803 for enhanced growth, tolerance, and chemical production
Yao L, Shabestary K, Björk SM, ..., Jahn M, Hudson EP
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Paul Hudson SciLifeLab Fellow
DOI Crossref
Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination
Ard R, Thomas Q, Li B, ..., Pelechano V, Marquardt S
- - (-) - [2019-10-28; online 2019-10-28]
SciLifeLab Fellow
PubMed DOI Crossref
Sharing Data from Molecular Simulations.
Abraham M, Apostolov R, Barnoud J, ..., Woods C, Zhmurov A
J Chem Inf Model 59 (10) 4093-4099 [2019-10-28; online 2019-10-11]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
CUTseq is a versatile method for preparing multiplexed DNA sequencing libraries from low-input samples.
Zhang X, Garnerone S, Simonetti M, ..., Bienko M, Crosetto N
Nat Commun 10 (1) 4732 [2019-10-18; online 2019-10-18]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates.
Eriksson O, Velikyan I, Haack T, ..., Pierrou S, Wagner M
Sci Rep 9 (1) 14960 [2019-10-18; online 2019-10-18]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Compositional and functional differences of the mucosal microbiota along the intestine of healthy individuals
Vaga S, Lee S, Ji B, ..., Engstrand L, Shoaie S
- - (-) - [2019-10-16; online 2019-10-16]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Dual Bioorthogonal Labeling of the Amyloid-β Protein Precursor Facilitates Simultaneous Visualization of the Protein and Its Cleavage Products.
van Husen LS, Schedin-Weiss S, Trung MN, ..., Elsässer SJ, Tjernberg LO
J. Alzheimers Dis. 72 (2) 537-548 [2019-10-15; online 2019-10-15]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
A Fluorescent Kinase Inhibitor that Exhibits Diagnostic Changes in Emission upon Binding.
Fleming CL, Sandoz PA, Inghardt T, ..., Grøtli M, Andréasson J
Angew. Chem. Int. Ed. Engl. 58 (42) 15000-15004 [2019-10-14; online 2019-09-05]
Patrick Sandoz SciLifeLab Fellow
DOI Crossref
A Fluorescent Kinase Inhibitor that Exhibits Diagnostic Changes in Emission upon Binding
Fleming CL, Sandoz PA, Inghardt T, ..., Grøtli M, Andréasson J
Angewandte Chemie 131 (42) 15142-15146 [2019-10-14; online 2019-09-05]
Patrick Sandoz SciLifeLab Fellow
PubMed DOI Crossref
Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe.
Cardozo Pinto DF, Yang H, Pollak Dorocic I, ..., Smidt MP, Lammel S
Nat Commun 10 (1) 4633 [2019-10-11; online 2019-10-11]
Iskra Pollak Dorocic SciLifeLab Fellow
PubMed DOI Crossref
Remodeling the genome with DNA twists.
Bowman GD, Deindl S
Science (New York, N.Y.) 366 (6461) 35-36 [2019-10-04; online 2019-10-12]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
Gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure
Zrimec J, Buric F, Muhammad AS, ..., Töpel M, Zelezniak A
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Aleksej Zelezniak SciLifeLab Fellow
DOI Crossref
Expanding functional protein sequence space using generative adversarial networks
Repecka D, Jauniskis V, Karpus L, ..., Engqvist MKM, Zelezniak A
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Aleksej Zelezniak SciLifeLab Fellow
DOI Crossref
Ecosystem responses to increased organic carbon concentration: comparing results based on long-term monitoring and whole-lake experimentation
Kankaala P, Arvola L, Hiltunen M, ..., Tulonen T, Vesala S
Inland Waters 9 (4) 489-502 [2019-10-02; online 2019-07-30]
Sari Peura SciLifeLab Fellow
DOI Crossref
Tiled STED Imaging of Extended Sample Regions
Alvelid J, Testa I
- - (-) - [2019-10-01; online 2019-10-01]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
VGLUT2 rs2290045 genotype moderates environmental sensitivity to alcohol-related problems in three samples of youths.
Vrettou M, Nilsson KW, Tuvblad C, ..., Nylander I, Comasco E
Eur Child Adolesc Psychiatry 28 (10) 1329-1340 [2019-10-00; online 2019-02-25]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI.
Espes D, Manell E, Rydén A, ..., Jansson L, Eriksson O
Acta diabetologica 56 (10) 1113-1120 [2019-10-00; online 2019-04-26]
Daniel Espes Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
High-definition spatial transcriptomics for in situ tissue profiling.
Vickovic S, Eraslan G, Salmén F, ..., Regev A, Ståhl PL
Nat. Methods 16 (10) 987-990 [2019-10-00; online 2019-09-09]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Genetic basis and timing of a major mating system shift in Capsella.
Bachmann JA, Tedder A, Laenen B, ..., Castric V, Slotte T
New Phytol. 224 (1) 505-517 [2019-10-00; online 2019-08-01]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Association between Transcription Factor AP-2B genotype, obesity, insulin resistance and dietary intake in a longitudinal birth cohort study.
Joost U, Villa I, Comasco E, ..., Veidebaum T, Harro J
Int J Obes (Lond) 43 (10) 2095-2106 [2019-10-00; online 2019-06-17]
Erika Comasco SciLifeLab Fellow
DOI Crossref
High photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopy
Schneider F, Hernandez-Varas P, Lagerholm BC, ..., Eggeling C, Urbančič I
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Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
EvoChromo: towards a synthesis of chromatin biology and evolution.
Drinnenberg IA, Berger F, Elsässer SJ, ..., Warnecke T, Wolfe KH
Development 146 (19) - [2019-09-26; online 2019-09-26]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Cytoplasmic protein misfolding titrates Hsp70 to activate nuclear Hsf1.
Masser AE, Kang W, Roy J, ..., Friedländer MR, Andréasson C
Elife 8 (-) - [2019-09-25; online 2019-09-25]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Chromatin conformation remains stable upon extensive transcriptional changes driven by heat shock.
Ray J, Munn PR, Vihervaara A, ..., Danko CG, Lis JT
Proc. Natl. Acad. Sci. U.S.A. 116 (39) 19431-19439 [2019-09-24; online 2019-09-10]
Anniina Vihervaara SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of The nucleosome core particle remembers its position through DNA replication and RNA transcription.
Elsässer S
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SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
What industry can teach academia.
Mao Y
Science (New York, N.Y.) 365 (6459) 1342 [2019-09-20; online 2019-10-12]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells.
Kumar B, Elsässer SJ
Cell Reports 28 (12) 3274-3284.e5 [2019-09-17; online 2019-09-19]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
Nuclear gene proximity and protein interactions shape transcript covariances in mammalian single cells
Tarbier M, Mackowiak SD, Frade J, ..., Gallant CJ, Friedländer MR
- - (-) - [2019-09-16; online 2019-09-16]
DDLS Fellow Magda Bienko Marc Friedländer Marcel Tarbier SciLifeLab Fellow
PubMed DOI Crossref
Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density.
Steinkühler J, Sezgin E, Urbančič I, Eggeling C, Dimova R
Commun Biol 2 (-) 337 [2019-09-13; online 2019-09-13]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Splotch: Robust estimation of aligned spatial temporal gene expression data
Äijö T, Maniatis S, Vickovic S, ..., Lundeberg J, Bonneau R
- - (-) - [2019-09-05; online 2019-09-05]
Sanja Vickovic SciLifeLab Fellow
DOI Crossref
Author response: Cytoplasmic protein misfolding titrates Hsp70 to activate nuclear Hsf1
Masser AE, Kang W, Roy J, ..., Friedländer MR, Andréasson C
- - (-) - [2019-09-03; online 2019-09-03]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism.
von Beek C, Waern I, Eriksson J, ..., Guss B, Pejler G
Cell. Microbiol. 21 (9) e13064 [2019-09-00; online 2019-07-07]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut.
Bakkeren E, Huisman JS, Fattinger SA, ..., Diard M, Hardt WD
Nature 573 (7773) 276-280 [2019-09-00; online 2019-09-04]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Real-time prediction of influenza outbreaks in Belgium.
Miranda GHB, Baetens JM, Bossuyt N, Bruno OM, De Baets B
Epidemics 28 (-) 100341 [2019-09-00; online 2019-04-18]
Gisele Miranda SciLifeLab Fellow
PubMed DOI Crossref
Impact of demography on linked selection in two outcrossing Brassicaceae species.
Mattila TM, Laenen B, Horvath R, ..., Savolainen O, Slotte T
Ecol Evol 9 (17) 9532-9545 [2019-09-00; online 2019-08-13]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Genomic data provide new insights on the demographic history and the extent of recent material transfers in Norway spruce.
Chen J, Li L, Milesi P, ..., Vendramin GG, Lascoux M
Evol Appl 12 (8) 1539-1551 [2019-09-00; online 2019-04-30]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Early life stress and voluntary alcohol consumption in relation to Maoa methylation in male rats.
Bendre M, Granholm L, Drennan R, ..., Nylander I, Comasco E
Alcohol 79 (-) 7-16 [2019-09-00; online 2018-11-08]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
A widely used sampling device in colorectal cancer screening programmes allows for large-scale microbiome studies.
Gudra D, Shoaie S, Fridmanis D, ..., Leja M, Engstrand L
Gut 68 (9) 1723-1725 [2019-09-00; online 2018-09-21]
Saeed Shoaie SciLifeLab Fellow
DOI Crossref
633 Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration
Li D, Kular L, Vij M, ..., Jagodic M, Xu Landén N
J. Invest. Dermatol. 139 (9) S323 [2019-09-00; online 2019-09-00]
Magda Bienko SciLifeLab Fellow
DOI Crossref
Combined mRNA and protein single cell analysis in a dynamic cellular system using SPARC
Reimegård J, Danielsson M, Tarbier M, ..., Friedländer MR, Gallant CJ
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DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
PubMed DOI Crossref
Turning Up the Heat: Local Temperature Control During in vivo Imaging of Immune Cells.
Ahl D, Eriksson O, Sedin J, ..., Christoffersson G, Phillipson M
Front Immunol 10 (-) 2036 [2019-08-27; online 2019-08-27]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Nanoscale dynamics of cholesterol in the cell membrane.
Pinkwart K, Schneider F, Lukoseviciute M, ..., Eggeling C, Sezgin E
J. Biol. Chem. 294 (34) 12599-12609 [2019-08-23; online 2019-07-03]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Molecular Basis and Ecological Relevance of Caulobacter Cell Filamentation in Freshwater Habitats.
Heinrich K, Leslie DJ, Morlock M, Bertilsson S, Jonas K
MBio 10 (4) - [2019-08-20; online 2019-08-20]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Progress towards the Tree of Eukaryotes.
Keeling PJ, Burki F
Curr. Biol. 29 (16) R808-R817 [2019-08-19; online 2019-08-21]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
MRPS25 mutations impair mitochondrial translation and cause encephalomyopathy.
Bugiardini E, Mitchell AL, Rosa ID, ..., Pitceathly RDS, Spinazzola A
Hum. Mol. Genet. 28 (16) 2711-2719 [2019-08-15; online 2019-05-01]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer.
Cadenas C, Vosbeck S, Edlund K, ..., Marchan R, Hengstler JG
Int. J. Cancer 145 (4) 901-915 [2019-08-15; online 2019-02-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Chemoselective probe for detailed analysis of ketones and aldehydes produced by gut microbiota in human samples.
Conway LP, Garg N, Lin W, ..., Löhr JM, Globisch D
Chem. Commun. (Camb.) 55 (62) 9080-9083 [2019-08-11; online 2019-07-09]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
DiscoverY: a classifier for identifying Y chromosome sequences in male assemblies.
Rangavittal S, Stopa N, Tomaszkiewicz M, ..., Makova KD, Medvedev P
BMC Genomics 20 (1) 641 [2019-08-09; online 2019-08-09]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5' structure element.
Romilly C, Deindl S, Wagner EGH
Proc. Natl. Acad. Sci. U.S.A. 116 (32) 15901-15906 [2019-08-06; online 2019-07-18]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
Faculty Opinions recommendation of Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome.
Amunts A
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Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of A cryo-FIB lift-out technique enables molecular-resolution cryo-ET within native Caenorhabditis elegans tissue.
Amunts A
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Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Tools for Bioimaging Pancreatic β Cells in Diabetes.
Kang NY, Soetedjo AAP, Amirruddin NS, ..., Eriksson O, Teo AKK
Trends in molecular medicine 25 (8) 708-722 [2019-08-00; online 2019-06-06]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Strategies for increasing the throughput of super-resolution microscopies.
Mahecic D, Testa I, Griffié J, Manley S
Curr Opin Chem Biol 51 (-) 84-91 [2019-08-00; online 2019-06-15]
DDLS Fellow Ilaria Testa Juliette Griffie SciLifeLab Fellow
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Single-cell expression noise and gene-body methylation in Arabidopsis thaliana.
Horvath R, Laenen B, Takuno S, Slotte T
Heredity (Edinb) 123 (2) 81-91 [2019-08-00; online 2019-01-16]
SciLifeLab Fellow Tanja Slotte
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Hypothalamic-pituitary-adrenal axis responsiveness, startle response, and sensorimotor gating in late pregnancy.
Breedh J, Comasco E, Hellgren C, ..., Skalkidou A, Poromaa IS
Psychoneuroendocrinology 106 (-) 1-8 [2019-08-00; online 2019-03-15]
Erika Comasco SciLifeLab Fellow
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Human prenatal exposure to polychlorinated biphenyls (PCBs) and risk behaviors in adolescence.
Dickerson AS, Ransome Y, Karlsson O
Environ Int 129 (-) 247-255 [2019-08-00; online 2019-05-27]
Oskar Karlsson SciLifeLab Fellow
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Elucidating the Reprograming of Colorectal Cancer Metabolism Using Genome-Scale Metabolic Modeling.
Zhang C, Aldrees M, Arif M, ..., Mardinoglu A, Aziz MA
Front Oncol 9 (-) 681 [2019-07-30; online 2019-07-30]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Amyloid fibril polymorphism and cell-specific toxicity in vivo.
Jonson M, Nyström S, Sandberg A, ..., Thor S, Hammarström P
Amyloid 26 (sup1) 136-137 [2019-07-26; online 2019-07-26]
SciLifeLab Fellow Wojciech Michno
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Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis.
Smillie CS, Biton M, Ordovas-Montanes J, ..., Xavier RJ, Regev A
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Sanja Vickovic SciLifeLab Fellow
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Constitutive Serotonin Transporter Reduction Resembles Maternal Separation with Regard to Stress-Related Gene Expression.
Comasco E, Schijven D, de Maeyer H, ..., Sundström-Poromaa I, Olivier JDA
ACS Chem Neurosci 10 (7) 3132-3142 [2019-07-17; online 2019-01-23]
Erika Comasco SciLifeLab Fellow
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Assessment of weather-based influent scenarios for a WWTP: Application of a pattern recognition technique.
Borzooei S, Miranda GHB, Teegavarapu R, ..., Meucci L, Zanetti MC
J Environ Manage 242 (-) 450-456 [2019-07-15; online 2019-05-06]
Gisele Miranda SciLifeLab Fellow
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The Potential Use of Metabolic Cofactors in Treatment of NAFLD.
Mardinoglu A, Ural D, Zeybel M, ..., Uhlén M, Borén J
Nutrients 11 (7) 1578 [2019-07-12; online 2019-07-12]
Adil Mardinoglu SciLifeLab Fellow
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Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nirwan N, Itoh Y, Singh P, ..., Amunts A, Saikrishnan K
Nat Commun 10 (1) 3058 [2019-07-11; online 2019-07-11]
Alexey Amunts SciLifeLab Fellow
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Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome
Barandun J, Hunziker M, Vossbrinck CR, Klinge S
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Jonas Barandun SciLifeLab Fellow
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Molecular insights from conformational ensembles via machine learning
Fleetwood O, Kasimova MA, Westerlund AM, Delemotte L
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Lucie Delemotte SciLifeLab Fellow
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Coupled Enzymatic Treatment and Mass Spectrometric Analysis for Identification of Glucuronidated Metabolites in Human Samples.
Correia MSP, Rao M, Ballet C, Globisch D
Chembiochem 20 (13) 1678-1683 [2019-07-01; online 2019-05-08]
Daniel Globisch SciLifeLab Fellow
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Regulation of the replication initiator DnaA in Caulobacter crescentus.
Felletti M, Omnus DJ, Jonas K
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862 (7) 697-705 [2019-07-00; online 2018-01-31]
Kristina Jonas SciLifeLab Fellow
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Plasma Proteomics Analysis Reveals Dysregulation of Complement Proteins and Inflammation in Acquired Obesity-A Study on Rare BMI-Discordant Monozygotic Twin Pairs.
Sahebekhtiari N, Saraswat M, Joenväärä S, ..., Renkonen R, Pietiläinen KH
Proteomics Clin Appl 13 (4) e1800173 [2019-07-00; online 2019-02-05]
Adil Mardinoglu SciLifeLab Fellow
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Outlining the proton-conduction pathway in otopetrin channels.
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Nat. Struct. Mol. Biol. 26 (7) 528-530 [2019-07-00; online 2019-06-27]
Lucie Delemotte SciLifeLab Fellow
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Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain.
Bigalke JM, Aibara S, Roth R, ..., Amunts A, Sandmark J
Sci Adv 5 (7) eaau4202 [2019-07-00; online 2019-07-31]
Alexey Amunts SciLifeLab Fellow
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The Next Generation of Pattern Recognition Receptor Agonists: Improving Response Rates in Cancer Immunotherapy.
O' Donovan DH, Mao Y, Mele DA
Current medicinal chemistry 27 (34) 5654-5674 [2019-06-30; online 2019-06-30]
SciLifeLab Fellow Yumeng Mao
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GPR44 as a Target for Imaging Pancreatic Beta-Cell Mass.
Eriksson O
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Olof Eriksson SciLifeLab Fellow
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Shotgun Environmental DNA, Pollen, and Macrofossil Analysis of Lateglacial Lake Sediments From Southern Sweden
Parducci L, Alsos IG, Unneberg P, ..., Slotte T, Wohlfarth B
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Mitotically heritable effects of BMAA on striatal neural stem cell proliferation and differentiation.
Pierozan P, Karlsson O
Cell Death Dis 10 (7) 478 [2019-06-17; online 2019-06-17]
Oskar Karlsson SciLifeLab Fellow
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Conformational switches control early maturation of the eukaryotic small ribosomal subunit.
Hunziker M, Barandun J, Buzovetsky O, ..., Molina H, Klinge S
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Jonas Barandun SciLifeLab Fellow
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iNetModels 2.0: an interactive visualization and database of multi-omics data
Arif M, Zhang C, Li X, ..., Uhlen M, Mardinoglu A
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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RMetD2: a tool for integration of relative transcriptomics data into Genome-scale metabolic models
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Adil Mardinoglu SciLifeLab Fellow
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Regulatory Immune Mechanisms beyond Regulatory T Cells.
Christoffersson G, von Herrath M
Trends Immunol. 40 (6) 482-491 [2019-06-00; online 2019-05-14]
Gustaf Christoffersson SciLifeLab Fellow
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Growth-driven displacement of protein aggregates along the cell length ensures partitioning to both daughter cells in Caulobacter crescentus.
Schramm FD, Schroeder K, Alvelid J, Testa I, Jonas K
Mol. Microbiol. 111 (6) 1430-1448 [2019-06-00; online 2019-04-03]
Ilaria Testa Kristina Jonas SciLifeLab Fellow
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Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects.
Bergström CAS, Box K, Holm R, ..., Schäfer KJ, Teleki A
Eur J Pharm Biopharm 139 (-) 101-114 [2019-06-00; online 2019-03-09]
Alexandra Teleki SciLifeLab Fellow
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Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract.
Furter M, Sellin ME, Hansson GC, Hardt WD
Cell Reports 27 (9) 2665-2678.e3 [2019-05-28; online 2019-05-30]
Mikael Sellin SciLifeLab Fellow
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Abundance and diversity of resistomes differ between healthy human oral cavities and gut
Carr VR, Witherden E, Lee S, ..., Gomez-Cabrero D, Moyes DL
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Saeed Shoaie SciLifeLab Fellow
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Barcoded Consortium Infections Resolve Cell Type-Dependent Salmonella enterica Serovar Typhimurium Entry Mechanisms.
Di Martino ML, Ek V, Hardt WD, Eriksson J, Sellin ME
MBio 10 (3) - [2019-05-21; online 2019-05-21]
Mikael Sellin SciLifeLab Fellow
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Ice-Age Climate Adaptations Trap the Alpine Marmot in a State of Low Genetic Diversity.
Gossmann TI, Shanmugasundram A, Börno S, ..., Timmermann B, Ralser M
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Aleksej Zelezniak SciLifeLab Fellow
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Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production.
Paivandy A, Eriksson J, Melo FR, Sellin ME, Pejler G
Cell death discovery 5 (1) 95 [2019-05-15; online 2019-05-15]
Mikael Sellin SciLifeLab Fellow
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EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks.
Domingo-Prim J, Endara-Coll M, Bonath F, ..., Huertas P, Visa N
Nat Commun 10 (1) 2135 [2019-05-13; online 2019-05-13]
Marc Friedländer SciLifeLab Fellow
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Mucispirillum schaedleri Antagonizes Salmonella Virulence to Protect Mice against Colitis.
Herp S, Brugiroux S, Garzetti D, ..., Berry D, Stecher B
Cell Host Microbe 25 (5) 681-694.e8 [2019-05-08; online 2019-04-18]
Mikael Sellin SciLifeLab Fellow
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Multi-Omic Data Interpretation to Repurpose Subtype Specific Drug Candidates for Breast Cancer.
Turanli B, Karagoz K, Bidkhori G, ..., Mardinoglu A, Arga KY
Front Genet 10 (-) 420 [2019-05-07; online 2019-05-07]
Adil Mardinoglu SciLifeLab Fellow
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Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration.
Li D, Kular L, Vij M, ..., Jagodic M, Landén NX
Proc. Natl. Acad. Sci. U.S.A. 116 (19) 9443-9452 [2019-05-07; online 2019-04-24]
Magda Bienko SciLifeLab Fellow
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Long metabarcoding of the eukaryotic rDNA operon to phylogenetically and taxonomically resolve environmental diversity
Jamy M, Foster R, Barbera P, ..., Bass D, Burki F
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Fabien Burki SciLifeLab Fellow
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Energy landscapes reveal agonist control of GPCR activation via microswitches
Fleetwood O, Matricon P, Carlsson J, Delemotte L
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Jens Carlsson Lucie Delemotte SciLifeLab Fellow
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Long Time-Scale Atomistic Simulations of the Structure and Dynamics of Transcription Factor-DNA Recognition.
Liao Q, Lüking M, Krüger DM, ..., Kasson PM, Lynn Kamerlin SC
J Phys Chem B 123 (17) 3576-3590 [2019-05-02; online 2019-04-18]
SciLifeLab Fellow Sebastian Deindl
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Towards the new normal: Transcriptomic convergence and genomic legacy of the two subgenomes of an allopolyploid weed (Capsella bursa-pastoris).
Kryvokhyzha D, Milesi P, Duan T, ..., Glémin S, Lascoux M
PLoS Genet 15 (5) e1008131 [2019-05-00; online 2019-05-13]
Pascal Milesi SciLifeLab Fellow
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Stress-related genetic polymorphisms in association with peripartum depression symptoms and stress hormones: A longitudinal population-based study.
Skalkidou A, Poromaa IS, Iliadis SI, ..., Freyhult E, Comasco E
Psychoneuroendocrinology 103 (-) 296-305 [2019-05-00; online 2019-02-07]
Erika Comasco SciLifeLab Fellow
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GM1 locates to mature amyloid structures implicating a prominent role for glycolipid-protein interactions in Alzheimer pathology.
Michno W, Wehrli PM, Zetterberg H, Blennow K, Hanrieder J
Biochim Biophys Acta Proteins Proteom 1867 (5) 458-467 [2019-05-00; online 2018-09-28]
SciLifeLab Fellow Wojciech Michno
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Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology.
Michno W, Nyström S, Wehrli P, ..., Zetterberg H, Hanrieder J
J Biol Chem 294 (17) 6719-6732 [2019-04-26; online 2019-02-27]
SciLifeLab Fellow Wojciech Michno
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Non-Invasive Imaging Methodologies for Assessment of Radiation Damage to Bone Marrow and Kidneys from Peptide Receptor Radionuclide Therapy.
Ahlstedt J, Johansson E, Sydoff M, ..., Gram M, Eriksson O
Neuroendocrinology 110 (1-2) 130-138 [2019-04-19; online 2019-04-19]
Olof Eriksson SciLifeLab Fellow
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Discovery of functional alternatively spliced PKM transcripts in human cancers
Li X, Zhang C, Kim W, ..., Uhlen M, Mardinoglu A
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling.
Sabantsev A, Levendosky RF, Zhuang X, Bowman GD, Deindl S
Nat Commun 10 (1) 1720 [2019-04-12; online 2019-04-12]
SciLifeLab Fellow Sebastian Deindl
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Receptor-Independent Transfer of Low Density Lipoprotein Cargo to Biomembranes.
Axmann M, Sezgin E, Karner A, ..., Stangl H, Plochberger B
Nano Lett. 19 (4) 2562-2567 [2019-04-10; online 2019-03-08]
Erdinc Sezgin SciLifeLab Fellow
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iFISH is a publically available resource enabling versatile DNA FISH to study genome architecture.
Gelali E, Girelli G, Matsumoto M, ..., Crosetto N, Bienko M
Nat Commun 10 (1) 1636 [2019-04-09; online 2019-04-09]
Magda Bienko SciLifeLab Fellow
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Spatiotemporal dynamics of molecular pathology in amyotrophic lateral sclerosis.
Maniatis S, Äijö T, Vickovic S, ..., Bonneau R, Phatnani H
Science (New York, N.Y.) 364 (6435) 89-93 [2019-04-05; online 2019-04-06]
Sanja Vickovic SciLifeLab Fellow
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System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection.
Garcia-Moreno M, Noerenberg M, Ni S, ..., Mohammed S, Castello A
Mol. Cell 74 (1) 196-211.e11 [2019-04-04; online 2019-02-21]
SciLifeLab Fellow
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Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes.
Harms MJ, Li Q, Lee S, ..., Spalding KL, Boucher J
Cell Reports 27 (1) 213-225.e5 [2019-04-02; online 2019-04-04]
Adil Mardinoglu SciLifeLab Fellow
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Case Reports of Pre-clinical Replication Studies in Metabolism and Diabetes.
von Herrath M, Pagni PP, Grove K, ..., Karlsen AE, Petersen JS
Cell Metab. 29 (4) 795-802 [2019-04-02; online 2019-03-14]
Gustaf Christoffersson SciLifeLab Fellow
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New Phylogenomic Analysis of the Enigmatic Phylum Telonemia Further Resolves the Eukaryote Tree of Life.
Strassert JFH, Jamy M, Mylnikov AP, Tikhonenkov DV, Burki F
Mol. Biol. Evol. 36 (4) 757-765 [2019-04-01; online 2019-01-23]
Fabien Burki SciLifeLab Fellow
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Synthesis and preclinical evaluation of the CRTH2 antagonist [11C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass.
Eriksson J, Roy T, Sawadjoon S, ..., Eriksson O, Odell LR
Nucl. Med. Biol. 71 (-) 1-10 [2019-04-00; online 2019-04-13]
Olof Eriksson SciLifeLab Fellow
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Measuring nanoscale diffusion dynamics in cellular membranes with super-resolution STED-FCS.
Sezgin E, Schneider F, Galiani S, ..., Lagerholm BC, Eggeling C
Nat Protoc 14 (4) 1054-1083 [2019-04-00; online 2019-03-06]
Erdinc Sezgin SciLifeLab Fellow
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Liver macrophages regulate systemic metabolism through non-inflammatory factors.
Morgantini C, Jager J, Li X, ..., Bajgar A, Aouadi M
Nat Metab 1 (4) 445-459 [2019-04-00; online 2019-03-25]
Claudia Kutter SciLifeLab Fellow
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Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning.
Turanli B, Zhang C, Kim W, ..., Arga KY, Mardinoglu A
EBioMedicine 42 (-) 386-396 [2019-04-00; online 2019-03-21]
Adil Mardinoglu SciLifeLab Fellow
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Author Correction: Liver macrophages regulate systemic metabolism through non-inflammatory factors.
Morgantini C, Jager J, Li X, ..., Bajgar A, Aouadi M
Nat Metab 1 (4) 497 [2019-04-00; online 2019-04-01]
Claudia Kutter SciLifeLab Fellow
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Attempted syntheses of N-confused hydroporphyrins through modified Lindsey routes
Xiong R, Arkhypchuk AI, Eszter Borbas K
J. Porphyrins Phthalocyanines 23 (04n05) 589-598 [2019-04-00; online 2019-05-15]
Ruisheng Xiong SciLifeLab Fellow
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A whole-brain atlas of monosynaptic input targeting four different cell types in the medial prefrontal cortex of the mouse.
Ährlund-Richter S, Xuan Y, van Lunteren JA, ..., Meletis K, Carlén M
Nat. Neurosci. 22 (4) 657-668 [2019-04-00; online 2019-03-18]
Iskra Pollak Dorocic SciLifeLab Fellow
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Faculty Opinions recommendation of Engineering Epigenetic Regulation Using Synthetic Read-Write Modules.
Elsässer S, Lafranchi L
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SciLifeLab Fellow Simon Elsässer
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Comprehensive kinetic and substrate specificity analysis of an arylsulfatase from Helix pomatia using mass spectrometry.
Correia MSP, Ballet C, Meistermann H, Conway LP, Globisch D
Bioorg. Med. Chem. 27 (6) 955-962 [2019-03-15; online 2019-01-30]
Daniel Globisch SciLifeLab Fellow
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Faculty Opinions recommendation of Structures of human PRC2 with its cofactors AEBP2 and JARID2.
Elsässer S
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SciLifeLab Fellow Simon Elsässer
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Expression of PD-L1 and PD-1 in Chemoradiotherapy-Naïve Esophageal and Gastric Adenocarcinoma: Relationship With Mismatch Repair Status and Survival.
Svensson MC, Borg D, Zhang C, ..., Leandersson K, Jirström K
Front Oncol 9 (-) 136 [2019-03-13; online 2019-03-13]
Adil Mardinoglu SciLifeLab Fellow
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Quantitative multiplexed ChIP reveals global alterations that shape promoter bivalency in ground state embryonic stem cells
Kumar B, Elsässer SJ
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SciLifeLab Fellow Simon Elsässer
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Vertical stratification of bacteria and archaea in sediments of a small boreal humic lake.
Rissanen AJ, Peura S, Mpamah PA, ..., Mäki A, Nykänen H
FEMS Microbiol. Lett. 366 (5) - [2019-03-01; online 2019-02-27]
Sari Peura SciLifeLab Fellow
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Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function.
Liu Z, Zhang C, Lee S, ..., Boren J, Mardinoglu A
Metab. Eng. 52 (-) 263-272 [2019-03-00; online 2019-01-04]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Plant microRNAs in human sera are likely contaminants.
Fromm B, Kang W, Rovira C, ..., Friedländer MR, Tosar JP
J Nutr Biochem 65 (-) 139-140 [2019-03-00; online 2018-09-05]
Marc Friedländer SciLifeLab Fellow
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Pervasive population genomic consequences of genome duplication in Arabidopsis arenosa.
Monnahan P, Kolář F, Baduel P, ..., Bomblies K, Yant L
Nat Ecol Evol 3 (3) 457-468 [2019-03-00; online 2019-02-25]
SciLifeLab Fellow Tanja Slotte
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High-density spatial transcriptomics arrays for in situ tissue profiling
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Sanja Vickovic SciLifeLab Fellow
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Ecological strategy and genetic load in the shepherd’s purse ( Capsella bursa-pastoris ) from the core and the limit of its natural range
Orsucci M, Milesi P, Hansen J, ..., Glémin S, Lascoux M
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Pascal Milesi SciLifeLab Fellow
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Long-term balancing selection drives evolution of immunity genes in Capsella.
Koenig D, Hagmann J, Li R, ..., Wright SI, Weigel D
Elife 8 (-) - [2019-02-26; online 2019-02-26]
SciLifeLab Fellow Tanja Slotte
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Evolutionary Implications of the microRNA- and piRNA Complement of Lepidodermella squamata (Gastrotricha).
Fromm B, Tosar JP, Aguilera F, ..., Bachmann L, Hejnol A
Noncoding RNA 5 (1) 19 [2019-02-22; online 2019-02-22]
Marc Friedländer SciLifeLab Fellow
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First-in-class positron emission tomography tracer for the glucagon receptor.
Velikyan I, Haack T, Bossart M, ..., Wagner M, Eriksson O
EJNMMI Res 9 (1) 17 [2019-02-15; online 2019-02-15]
Olof Eriksson SciLifeLab Fellow
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Heterogeneity of Metabolic Defects in Type 2 Diabetes and Its Relation to Reactive Oxygen Species and Alterations in Beta-Cell Mass.
Elksnis A, Martinell M, Eriksson O, Espes D
Front. Physiol. 10 (-) 107 [2019-02-13; online 2019-02-13]
Daniel Espes Olof Eriksson SciLifeLab Fellow
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Zinc depletion does not necessarily induce ribosome hibernation in mycobacteria.
Tobiasson V, Dow A, Prisic S, Amunts A
Proc. Natl. Acad. Sci. U.S.A. 116 (7) 2395-2397 [2019-02-12; online 2019-01-25]
Alexey Amunts SciLifeLab Fellow
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Correction to: An Application-Directed, Versatile DNA FISH Platform for Research and Diagnostics.
Gelali E, Custodio J, Girelli G, ..., Crosetto N, Bienko M
Methods in molecular biology (Clifton, N.J.) 1766 (-) E1 [2019-02-10; online 2019-02-10]
Magda Bienko SciLifeLab Fellow
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A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection.
Wright SC, Kozielewicz P, Kowalski-Jahn M, ..., Carlsson J, Schulte G
Nat Commun 10 (1) 667 [2019-02-08; online 2019-02-08]
Jens Carlsson SciLifeLab Fellow
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Spatiotemporal dissection of the cell cycle with single-cell proteogenomics
Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan D, Lundberg E
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Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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Kinetic modeling of the Calvin cycle identifies flux control and stable metabolomes in Synechocystis carbon fixation.
Janasch M, Asplund-Samuelsson J, Steuer R, Hudson EP
J. Exp. Bot. 70 (3) 973-983 [2019-02-05; online 2018-10-30]
Paul Hudson SciLifeLab Fellow
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Structural Patching Fosters Divergence of Mitochondrial Ribosomes.
Petrov AS, Wood EC, Bernier CR, ..., Brown A, Amunts A
Mol. Biol. Evol. 36 (2) 207-219 [2019-02-01; online 2018-12-06]
Alexey Amunts SciLifeLab Fellow
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Smart scanning for low-illumination and fast RESOLFT nanoscopy in vivo.
Dreier J, Castello M, Coceano G, ..., Vicidomini G, Testa I
Nat Commun 10 (1) 556 [2019-02-01; online 2019-02-01]
Ilaria Testa SciLifeLab Fellow
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Transcription-driven chromatin repression of Intragenic transcription start sites.
Nielsen M, Ard R, Leng X, ..., Pelechano V, Marquardt S
PLoS Genet 15 (2) e1007969 [2019-02-00; online 2019-02-01]
SciLifeLab Fellow
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Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysis.
Benfeitas R, Bidkhori G, Mukhopadhyay B, ..., Kunos G, Mardinoglu A
EBioMedicine 40 (-) 471-487 [2019-02-00; online 2018-12-31]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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A De Novo Mutation Associated with Epilepsy Enhances KV1.2 Voltage Dependence, Suppressing Neuronal Excitability
Pantazis A, Kaneko M, Westerlund AM, ..., Saitta S, Olcese R
Biophysical Journal 116 (3) 247a [2019-02-00; online 2019-02-00]
Lucie Delemotte SciLifeLab Fellow
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Discovery of KIRREL as a biomarker for prognostic stratification of patients with thin melanoma.
Lundgren S, Fagerström-Vahman H, Zhang C, ..., Nodin B, Jirström K
Biomark Res 7 (1) 1 [2019-01-14; online 2019-01-14]
Adil Mardinoglu SciLifeLab Fellow
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Negative Association Between Allopregnanolone and Cerebral Serotonin Transporter Binding in Healthy Women of Fertile Age.
Sundström Poromaa I, Comasco E, Bäckström T, ..., Jensen P, Frokjaer VG
Front Psychol 9 (-) 2767 [2019-01-11; online 2019-01-11]
Erika Comasco SciLifeLab Fellow
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The Circulating Transcriptome as a Source of Biomarkers for Melanoma.
Solé C, Tramonti D, Schramm M, ..., Middleton MR, Lawrie CH
Cancers (Basel) 11 (1) 70 [2019-01-10; online 2019-01-10]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Decreased Snow Cover Stimulates Under-Ice Primary Producers but Impairs Methanotrophic Capacity.
Garcia SL, Szekely AJ, Bergvall C, Schattenhofer M, Peura S
mSphere 4 (1) - [2019-01-09; online 2019-01-09]
Sarahi Garcia Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Ascetosporea.
Bass D, Ward GM, Burki F
Curr. Biol. 29 (1) R7-R8 [2019-01-07; online 2019-01-09]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium.
Westermann AJ, Venturini E, Sellin ME, ..., Hardt WD, Vogel J
MBio 10 (1) - [2019-01-02; online 2019-01-02]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System.
de Jong JW, Afjei SA, Pollak Dorocic I, ..., Deisseroth K, Lammel S
Neuron 101 (1) 133-151.e7 [2019-01-02; online 2018-11-29]
Iskra Pollak Dorocic SciLifeLab Fellow
PubMed DOI Crossref
Revisions to the Classification, Nomenclature, and Diversity of Eukaryotes.
Adl SM, Bass D, Lane CE, ..., Zlatogursky V, Zhang Q
J. Eukaryot. Microbiol. 66 (1) 4-119 [2019-01-00; online 2018-09-27]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Phylogenomics supports the monophyly of the Cercozoa.
Irwin NAT, Tikhonenkov DV, Hehenberger E, ..., Burki F, Keeling PJ
Mol. Phylogenet. Evol. 130 (-) 416-423 [2019-01-00; online 2018-10-11]
Fabien Burki SciLifeLab Fellow
DOI Crossref
Nanostructured Minerals and Vitamins for Food Fortification and Food Supplementation
Knijnenburg JTN, Posavec L, Teleki A
- - (-) 63-98 [2019-00-00; online 2019-00-00]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
Helix Breaking Transition in the S4 of HCN Channel is Critical for Hyperpolarization-Dependent Gating
Kasimova MA, Tewari D, Cowgill J, ..., Delemotte L, Chanda B
SSRN Journal - (-) - [2019-00-00; online 2019-00-00]
Lucie Delemotte SciLifeLab Fellow

Year 2018

PubMed DOI Crossref
The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass.
Jahan M, Johnström P, Selvaraju RK, ..., Halldin C, Eriksson O
EJNMMI Res 8 (1) 113 [2018-12-27; online 2018-12-27]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API
Desvignes T, Loher P, Eilbeck K, ..., Halushka MK, Pantano L
- - (-) - [2018-12-25; online 2018-12-25]
Marc Friedländer SciLifeLab Fellow
DOI Crossref
Evolutionary implications of the microRNA- and piRNA complement of Lepidodermella squamata (Gastrotricha)
Fromm B, Tosar JP, Aguilera F, ..., Bachmann L, Hejnol A
- - (-) - [2018-12-21; online 2018-12-21]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
CD45 exclusion- and cross-linking-based receptor signaling together broaden FcεRI reactivity.
Felce JH, Sezgin E, Wane M, ..., Eggeling C, Davis SJ
Sci Signal 11 (561) - [2018-12-18; online 2018-12-18]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
acI Actinobacteria Assemble a Functional Actinorhodopsin with Natively Synthesized Retinal.
Dwulit-Smith JR, Hamilton JJ, Stevenson DM, ..., McMahon KD, Forest KT
Applied and environmental microbiology 84 (24) - [2018-12-15; online 2018-11-30]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks.
Bonath F, Domingo-Prim J, Tarbier M, Friedländer MR, Visa N
Nucleic Acids Res. 46 (22) 11869-11882 [2018-12-14; online 2018-11-13]
DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
PubMed DOI Crossref
Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes.
Bidkhori G, Benfeitas R, Klevstig M, ..., Boren J, Mardinoglu A
Proc. Natl. Acad. Sci. U.S.A. 115 (50) E11874-E11883 [2018-12-11; online 2018-11-27]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
miRTrace reveals the organismal origins of microRNA sequencing data.
Kang W, Eldfjell Y, Fromm B, ..., Biryukova I, Friedländer MR
Genome Biol. 19 (1) 213 [2018-12-04; online 2018-12-04]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
FZD5 is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs.
Wright SC, Cañizal MCA, Benkel T, ..., Schulte G, Hoffmann C
Sci Signal 11 (559) eaar5536 [2018-12-04; online 2018-12-04]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Tumor suppressor PNRC1 blocks rRNA maturation by recruiting the decapping complex to the nucleolus.
Gaviraghi M, Vivori C, Pareja Sanchez Y, ..., Cittaro D, Tonon G
EMBO J. 37 (23) - [2018-12-03; online 2018-10-29]
SciLifeLab Fellow
PubMed DOI Crossref
Methanogens and Iron-Reducing Bacteria: the Overlooked Members of Mercury-Methylating Microbial Communities in Boreal Lakes.
Bravo AG, Peura S, Buck M, ..., Björn E, Bertilsson S
Applied and environmental microbiology 84 (23) - [2018-12-01; online 2018-11-15]
Sari Peura SciLifeLab Fellow
DOI Crossref
HYPERPARAMETER OPTIMIZATION FOR APPROXIMATE BAYESIAN COMPUTATION
Singh P, Hellander A
- - (-) - [2018-12-00; online 2018-12-00]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer.
Gotthardt M, Eizirik DL, Aanstoot HJ, ..., Cnop M, Brom M
Diabetologia 61 (12) 2516-2519 [2018-12-00; online 2018-10-03]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Control of hepatic gluconeogenesis by Argonaute2.
Yan X, Wang Z, Bishop CA, ..., Willnow TE, Poy MN
Mol Metab 18 (-) 15-24 [2018-12-00; online 2018-10-09]
DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
DOI Crossref
Bridging gaps in transposable element research with single-molecule and single-cell technologies
Kutter C, Jern P, Suh A
Mobile DNA 9 (1) - [2018-12-00; online 2018-12-06]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
RollFISH achieves robust quantification of single-molecule RNA biomarkers in paraffin-embedded tumor tissue samples.
Wu C, Simonetti M, Rossell C, ..., Crosetto N, Nilsson M
Commun Biol 1 (1) 209 [2018-11-28; online 2018-11-28]
Magda Bienko SciLifeLab Fellow
DOI Crossref
The human secretome – the proteins secreted from human cells
Uhlen M, Tegel H, Sivertsson Å, ..., Schiavone LH, Hober S
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Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice.
Håversen L, Sundelin JP, Mardinoglu A, ..., Levin M, Borén J
Sci Rep 8 (1) 16973 [2018-11-19; online 2018-11-19]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
The Circulating Transcriptome as a Source of Biomarkers for Melanoma
Solé C, Tramonti D, Schamm M, ..., Middleton MR, lawrie CH
- - (-) - [2018-11-19; online 2018-11-19]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Methanomethylophilus alvus Mx1201 Provides Basis for Mutual Orthogonal Pyrrolysyl tRNA/Aminoacyl-tRNA Synthetase Pairs in Mammalian Cells.
Meineke B, Heimgärtner J, Lafranchi L, Elsässer SJ
ACS chemical biology 13 (11) 3087-3096 [2018-11-16; online 2018-10-12]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
PREQUAL: detecting non-homologous characters in sets of unaligned homologous sequences.
Whelan S, Irisarri I, Burki F
Bioinformatics 34 (22) 3929-3930 [2018-11-15; online 2018-06-06]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Structural Characterization of Agonist Binding to Protease-Activated Receptor 2 through Mutagenesis and Computational Modeling.
Kennedy AJ, Ballante F, Johansson JR, ..., Nordqvist A, Carlsson J
ACS pharmacology & translational science 1 (2) 119-133 [2018-11-09; online 2018-10-16]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
A Network-Based Cancer Drug Discovery: From Integrated Multi-Omics Approaches to Precision Medicine.
Turanli B, Karagoz K, Gulfidan G, ..., Mardinoglu A, Arga KY
Curr. Pharm. Des. 24 (32) 3778-3790 [2018-11-07; online 2018-11-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Forces drive basement membrane invasion in Caenorhabditis elegans.
Cáceres R, Bojanala N, Kelley LC, ..., Sherwood DR, Plastino J
Proc. Natl. Acad. Sci. U.S.A. 115 (45) 11537-11542 [2018-11-06; online 2018-10-22]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon.
Sahlin K, Tomaszkiewicz M, Makova KD, Medvedev P
Nat Commun 9 (1) 4601 [2018-11-02; online 2018-11-02]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function.
Langlet F, Tarbier M, Haeusler RA, ..., Friedländer MR, Accili D
Mol Metab 17 (-) 49-60 [2018-11-00; online 2018-08-11]
DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
PubMed DOI Crossref
How to minimize dye-induced perturbations while studying biomembrane structure and dynamics: PEG linkers as a rational alternative.
Mobarak E, Javanainen M, Kulig W, ..., Rog T, Vattulainen I
Biochim Biophys Acta Biomembr 1860 (11) 2436-2445 [2018-11-00; online 2018-07-18]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Gene-environment interaction of monoamine oxidase A in relation to antisocial behaviour: current and future directions.
Nilsson KW, Åslund C, Comasco E, Oreland L
J Neural Transm (Vienna) 125 (11) 1601-1626 [2018-11-00; online 2018-06-07]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Barcoded solid-phase RNA capture for Spatial Transcriptomics profiling in mammalian tissue sections.
Salmén F, Ståhl PL, Mollbrink A, ..., Frisén J, Lundeberg J
Nat Protoc 13 (11) 2501-2534 [2018-11-00; online 2018-10-26]
Sanja Vickovic SciLifeLab Fellow
DOI Crossref
An optimized shape descriptor based on structural properties of networks
Miranda GHB, Machicao J, Bruno OM
Digital Signal Processing 82 (-) 216-229 [2018-11-00; online 2018-11-00]
Gisele Miranda SciLifeLab Fellow
DOI Crossref
Ribosome Profiling of Synechocystis Reveals Altered Ribosome Allocation at Carbon Starvation
Karlsen J, Asplund-Samuelsson J, Thomas Q, Jahn M, Hudson EP
mSystems 3 (5) - [2018-10-30; online 2018-10-30]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
A Robust Proton Flux (pHlux) Assay for Studying the Function and Inhibition of the Influenza A M2 Proton Channel.
Santner P, Martins JMDS, Laursen JS, ..., Willemoës M, Lindorff-Larsen K
Biochemistry 57 (41) 5949-5956 [2018-10-16; online 2018-10-03]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Chemoselective Probe Containing a Unique Bioorthogonal Cleavage Site for Investigation of Gut Microbiota Metabolism.
Garg N, Conway LP, Ballet C, ..., Löhr JM, Globisch D
Angew. Chem. Int. Ed. Engl. 57 (42) 13805-13809 [2018-10-15; online 2018-09-20]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Chemoselective Probe Containing a Unique Bioorthogonal Cleavage Site for Investigation of Gut Microbiota Metabolism
Garg N, Conway LP, Ballet C, ..., Löhr J‐, Globisch D
Angewandte Chemie 130 (42) 14001-14005 [2018-10-15; online 2018-09-20]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Growth of Cyanobacteria Is Constrained by the Abundance of Light and Carbon Assimilation Proteins.
Jahn M, Vialas V, Karlsen J, ..., Käll L, Hudson EP
Cell Reports 25 (2) 478-486.e8 [2018-10-09; online 2018-10-12]
DDLS Fellow Fredrik Edfors Paul Hudson SciLifeLab Fellow
DOI Crossref
Growth-driven displacement of protein aggregates along the cell length ensures partitioning to both daughter cells in Caulobacter crescentus
Schramm FD, Schroeder K, Alvelid J, Testa I, Jonas K
- - (-) - [2018-10-05; online 2018-10-05]
Ilaria Testa Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Rapid Isolation of the Mitoribosome from HEK Cells.
Aibara S, Andréll J, Singh V, Amunts A
J Vis Exp - (140) - [2018-10-04; online 2018-10-04]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Rapid Isolation of the Mitoribosome from HEK Cells
Aibara S, Andréll J, Singh V, Amunts A
J Vis Exp - (140) - [2018-10-04; online 2018-10-04]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Reconstitution of immune cell interactions in free-standing membranes.
Jenkins E, Santos AM, O'Brien-Ball C, ..., Eggeling C, Sezgin E
J. Cell. Sci. 132 (4) - [2018-10-02; online 2018-10-02]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA.
Delemotte L
J. Gen. Physiol. 150 (10) 1356-1359 [2018-10-01; online 2018-08-24]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Determining the molecular basis of voltage sensitivity in membrane proteins.
Kasimova MA, Lindahl E, Delemotte L
J. Gen. Physiol. 150 (10) 1444-1458 [2018-10-01; online 2018-08-27]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
High Cell Density Perfusion Culture has a Maintained Exoproteome and Metabolome.
Zamani L, Lundqvist M, Zhang Y, ..., Rockberg J, Chotteau V
Biotechnol J 13 (10) e1800036 [2018-10-00; online 2018-07-13]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
ESS: A Tool for Genome-Scale Quantification of Essentiality Score for Reaction/Genes in Constraint-Based Modeling.
Zhang C, Bidkhori G, Benfeitas R, ..., Uhlén M, Mardinoglu A
Front. Physiol. 9 (-) 1355 [2018-09-28; online 2018-09-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Effects of Design Choices on the Stiffness of Wireframe DNA Origami Structures.
Benson E, Mohammed A, Rayneau-Kirkhope D, ..., Orponen P, Högberg B
ACS Nano 12 (9) 9291-9299 [2018-09-25; online 2018-09-06]
Erik Benson SciLifeLab Fellow
DOI Crossref
Genetic basis and timing of a major mating system shift in Capsella
Bachmann JA, Tedder A, Laenen B, ..., Castric V, Slotte T
- - (-) - [2018-09-24; online 2018-09-24]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome.
Lovric A, Granér M, Bjornson E, ..., Mardinoglu A, Boren J
Sci Rep 8 (1) 14200 [2018-09-21; online 2018-09-21]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Meta-Analysis of Adiponectin as a Biomarker for the Detection of Metabolic Syndrome.
Liu Z, Liang S, Que S, ..., Zheng S, Mardinoglu A
Front. Physiol. 9 (-) 1238 [2018-09-19; online 2018-09-19]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Pervasive population genomic consequences of genome duplication in Arabidopsis arenosa
Monnahan P, Kolář F, Baduel P, ..., Bomblies K, Yant L
- - (-) - [2018-09-07; online 2018-09-07]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Excitation- and Emission-Wavelength-Based Multiplex Spectroscopy Using Red-Absorbing Near-Infrared-Emitting Lanthanide Complexes.
Xiong R, Mara D, Liu J, Van Deun R, Borbas KE
Journal of the American Chemical Society 140 (35) 10975-10979 [2018-09-05; online 2018-08-23]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Systematic overexpression study to find target enzymes enhancing production of terpenes in Synechocystis PCC 6803, using isoprene as a model compound.
Englund E, Shabestary K, Hudson EP, Lindberg P
Metab. Eng. 49 (-) 164-177 [2018-09-00; online 2018-07-17]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Mapping the Interface of a GPCR Dimer: A Structural Model of the A2A Adenosine and D2 Dopamine Receptor Heteromer.
Borroto-Escuela DO, Rodriguez D, Romero-Fernandez W, ..., Fuxe K, Carlsson J
Front. Pharmacol. 9 (-) 829 [2018-08-30; online 2018-08-30]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
DOI Crossref
Chromatin-sensitive cryptic promoters encode alternative protein isoforms in yeast
Wei W, Hennig BP, Wang J, ..., Steinmetz LM, Pelechano V
- - (-) - [2018-08-29; online 2018-08-29]
SciLifeLab Fellow
PubMed DOI Crossref
Statistical Analysis of Scanning Fluorescence Correlation Spectroscopy Data Differentiates Free from Hindered Diffusion.
Schneider F, Waithe D, Lagerholm BC, ..., Eggeling C, Fritzsche M
ACS Nano 12 (8) 8540-8546 [2018-08-28; online 2018-07-26]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Direct observation of rotation-coupled protein diffusion along DNA on the microsecond timescale
Marklund E, Amselem E, Kipper K, ..., Deindl S, Elf J
- - (-) - [2018-08-27; online 2018-08-27]
Emil Marklund SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Role of Gln222 in Photoswitching of Aequorea Fluorescent Proteins: A Twisting and H-Bonding Affair?
Storti B, Margheritis E, Abbandonato G, ..., Nifosì R, Bizzarri R
ACS chemical biology 13 (8) 2082-2093 [2018-08-17; online 2018-06-19]
Affiliated researcher Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Enhanced photon collection enables four dimensional fluorescence nanoscopy of living systems.
Masullo LA, Bodén A, Pennacchietti F, ..., Ratz M, Testa I
Nat Commun 9 (1) 3281 [2018-08-16; online 2018-08-16]
Affiliated researcher Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Surface Display of Small Affinity Proteins on Synechocystis sp. Strain PCC 6803 Mediated by Fusion to the Major Type IV Pilin PilA1.
Cengic I, Uhlén M, Hudson EP
J. Bacteriol. 200 (16) - [2018-08-15; online 2018-07-25]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Novel Autotrophic Organisms Contribute Significantly to the Internal Carbon Cycling Potential of a Boreal Lake.
Peura S, Buck M, Aalto SL, ..., Nykänen H, Eiler A
MBio 9 (4) - [2018-08-14; online 2018-08-14]
Sari Peura SciLifeLab Fellow
DOI Crossref
Spatiotemporal Dynamics of Molecular Pathology in Amyotrophic Lateral Sclerosis
Maniatis S, Äijö T, Vickovic S, ..., Bonneau R, Phatnani H
- - (-) - [2018-08-09; online 2018-08-09]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites.
Ballet C, Correia MSP, Conway LP, ..., Löhr JM, Globisch D
Chem Sci 9 (29) 6233-6239 [2018-08-07; online 2018-06-28]
Affiliated researcher Daniel Globisch SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
The environmental neurotoxin β-N-methylamino-L-alanine inhibits melatonin synthesis in primary pinealocytes and a rat model.
Pierozan P, Andersson M, Brandt I, Karlsson O
Journal of pineal research 65 (1) e12488 [2018-08-00; online 2018-04-06]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Scavenging of superoxide by a membrane-bound superoxide oxidase.
Lundgren CAK, Sjöstrand D, Biner O, ..., von Ballmoos C, Högbom M
Nat. Chem. Biol. 14 (8) 788-793 [2018-08-00; online 2018-06-18]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Publisher Correction: Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor.
Perez Boerema A, Aibara S, Paul B, ..., Lindahl E, Amunts A
Nat Plants 4 (8) 615 [2018-08-00; online 2018-07-25]
Alexey Amunts Björn Forsberg DDLS Fellow SciLifeLab Fellow
DOI Crossref
Interspecific variation in ploidy as a key plant trait outlining local extinction risks and community patterns in fragmented landscapes
Plue J, Kimberley A, Slotte T
Funct Ecol 32 (8) 2095-2106 [2018-08-00; online 2018-05-22]
Affiliated researcher SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Fast reversibly photoswitching red fluorescent proteins for live-cell RESOLFT nanoscopy.
Pennacchietti F, Serebrovskaya EO, Faro AR, ..., Mishin AS, Testa I
Nat. Methods 15 (8) 601-604 [2018-08-00; online 2018-07-09]
Affiliated researcher Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Disruption of A2AR-D2R Heteroreceptor Complexes After A2AR Transmembrane 5 Peptide Administration Enhances Cocaine Self-Administration in Rats.
Borroto-Escuela DO, Wydra K, Li X, ..., Filip M, Fuxe K
Mol. Neurobiol. 55 (8) 7038-7048 [2018-08-00; online 2018-01-30]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Targeted Repression of Essential Genes To Arrest Growth and Increase Carbon Partitioning and Biofuel Titers in Cyanobacteria.
Shabestary K, Anfelt J, Ljungqvist E, ..., Yao L, Hudson EP
ACS Synth. Biol. 7 (7) 1669-1675 [2018-07-20; online 2018-06-08]
Affiliated researcher Paul Hudson SciLifeLab Fellow
DOI Crossref
Methanomethylophilus alvus Mx1201 provides basis for mutual orthogonal pyrrolysyl tRNA/aminoacyl-tRNA synthetase pairs in mammalian cells
Meineke B, Heimgärtner J, Lafranchi L, Elsässer SJ
- - (-) - [2018-07-19; online 2018-07-19]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Metabolic Network-Based Identification and Prioritization of Anticancer Targets Based on Expression Data in Hepatocellular Carcinoma.
Bidkhori G, Benfeitas R, Elmas E, ..., Nielsen J, Mardinoglu A
Front. Physiol. 9 (-) 916 [2018-07-17; online 2018-07-17]
Adil Mardinoglu Affiliated researcher DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Nanoscale Spatiotemporal Diffusion Modes Measured by Simultaneous Confocal and Stimulated Emission Depletion Nanoscopy Imaging.
Schneider F, Waithe D, Galiani S, ..., Sezgin E, Eggeling C
Nano Lett. 18 (7) 4233-4240 [2018-07-11; online 2018-06-19]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Capturing the Onset of PRC2-Mediated Repressive Domain Formation.
Elsässer S
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SciLifeLab Fellow Simon Elsässer
DOI Crossref
Faculty Opinions recommendation of Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2.
Elsässer S
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SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Multimodal Chemical Imaging of Amyloid Plaque Polymorphism Reveals Aβ Aggregation Dependent Anionic Lipid Accumulations and Metabolism.
Michno W, Kaya I, Nyström S, ..., Zetterberg H, Hanrieder J
Anal. Chem. 90 (13) 8130-8138 [2018-07-03; online 2018-06-19]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus.
Carlsson PO, Espes D, Sedigh A, ..., Olerud J, Korsgren O
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 18 (7) 1735-1744 [2018-07-00; online 2018-02-02]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock.
Garre E, Pelechano V, Sánchez Del Pino M, Alepuz P, Sunnerhagen P
PLoS Genet 14 (7) e1007563 [2018-07-00; online 2018-07-30]
Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling.
Hertzog J, Dias Junior AG, Rigby RE, ..., Kohl A, Rehwinkel J
Eur. J. Immunol. 48 (7) 1120-1136 [2018-07-00; online 2018-04-06]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Cannabinoid Type 1 Receptors Are Upregulated During Acute Activation of Brown Adipose Tissue.
Lahesmaa M, Eriksson O, Gnad T, ..., Virtanen KA, Nuutila P
Diabetes 67 (7) 1226-1236 [2018-07-00; online 2018-04-12]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Associations of monoamine oxidase A gene first exon methylation with sexual abuse and current depression in women.
Checknita D, Ekström TJ, Comasco E, ..., Tiihonen J, Hodgins S
J Neural Transm (Vienna) 125 (7) 1053-1064 [2018-07-00; online 2018-03-29]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Multidimensional transcriptomics provides detailed information about immune cell distribution and identity in HER2+ breast tumors
Salmén F, Vickovic S, Larsson L, ..., Ståhl PL, Lundeberg J
- - (-) - [2018-06-29; online 2018-06-29]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Docking Screens for Dual Inhibitors of Disparate Drug Targets for Parkinson's Disease.
Jaiteh M, Zeifman A, Saarinen M, ..., Loza MI, Carlsson J
J Med Chem 61 (12) 5269-5278 [2018-06-28; online 2018-06-15]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Model Communities Hint at Promiscuous Metabolic Linkages between Ubiquitous Free-Living Freshwater Bacteria.
Garcia SL, Buck M, Hamilton JJ, ..., McMahon KD, Eiler A
mSphere 3 (3) - [2018-06-27; online 2018-05-30]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Understanding the Representative Gut Microbiota Dysbiosis in Metformin-Treated Type 2 Diabetes Patients Using Genome-Scale Metabolic Modeling.
Rosario D, Benfeitas R, Bidkhori G, ..., Shoaie S, Mardinoglu A
Front. Physiol. 9 (-) 775 [2018-06-25; online 2018-06-25]
Adil Mardinoglu Affiliated researcher Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Memote: A community driven effort towards a standardized genome-scale metabolic model test suite
Lieven C, Beber ME, Olivier BG, ..., Zakhartsev M, Zhang C
- - (-) - [2018-06-21; online 2018-06-21]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Understanding RNP remodelling uncovers RBPs functionally required for viral replication
Garcia-Moreno M, Noerenberg M, Ni S, ..., Mohammed S, Castello A
- - (-) - [2018-06-20; online 2018-06-20]
SciLifeLab Fellow
PubMed DOI Crossref
Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity.
Berglund E, Maaskola J, Schultz N, ..., Helleday T, Lundeberg J
Nat Commun 9 (1) 2419 [2018-06-20; online 2018-06-20]
Affiliated researcher Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Complementary studies of lipid membrane dynamics using iSCAT and super-resolved fluorescence correlation spectroscopy.
Reina F, Galiani S, Shrestha D, ..., Kukura P, Eggeling C
J. Phys. D: Appl. Phys. 51 (23) 235401 [2018-06-13; online 2018-05-16]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI.
Kipper K, Eremina N, Marklund E, ..., Elf J, Deindl S
PLoS ONE 13 (6) e0198416 [2018-06-01; online 2018-06-01]
Affiliated researcher Emil Marklund SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Systems biology in hepatology: approaches and applications.
Mardinoglu A, Boren J, Smith U, Uhlen M, Nielsen J
Nat Rev Gastroenterol Hepatol 15 (6) 365-377 [2018-06-00; online 2018-04-25]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Paternally expressed imprinted genes associate with hybridization barriers in Capsella.
Lafon-Placette C, Hatorangan MR, Steige KA, ..., Slotte T, Köhler C
Nat Plants 4 (6) 352-357 [2018-06-00; online 2018-05-28]
Affiliated researcher SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Molecular mechanisms driving transcriptional stress responses.
Vihervaara A, Duarte FM, Lis JT
Nat. Rev. Genet. 19 (6) 385-397 [2018-06-00; online 2018-03-21]
Anniina Vihervaara SciLifeLab Fellow
DOI Crossref
Increasing dominance of terrigenous organic matter in circumpolar freshwaters due to permafrost thaw
Wauthy M, Rautio M, Christoffersen KS, ..., Peura S, Vincent WF
Limnol Oceanogr Letters 3 (3) 186-198 [2018-06-00; online 2018-02-00]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Exploring the Viral Channel KcvPBCV-1 Function via Computation.
Andersson AEV, Kasimova MA, Delemotte L
J. Membr. Biol. 251 (3) 419-430 [2018-06-00; online 2018-02-23]
Affiliated researcher Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Elevated inflammation in association with alcohol abuse among Blacks but not Whites: results from the MIDUS biomarker study.
Ransome Y, Slopen N, Karlsson O, Williams DR
J Behav Med 41 (3) 374-384 [2018-06-00; online 2017-12-11]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Bioengineering with Endothelial Progenitor Cells Improves the Vascular Engraftment of Transplanted Human Islets.
Grapensparr L, Christoffersson G, Carlsson PO
Cell Transplant 27 (6) 948-956 [2018-06-00; online 2018-06-03]
Gustaf Christoffersson SciLifeLab Fellow
DOI Crossref
Gammaproteobacterial methanotrophs dominate methanotrophy in aerobic and anaerobic layers of boreal lake waters
Rissanen A, Saarenheimo J, Tiirola M, ..., Karvinen A, Nykänen H
Aquat. Microb. Ecol. 81 (3) 257-276 [2018-05-30; online 2018-05-30]
Affiliated researcher Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Emulsions Stabilized by Chitosan-Modified Silica Nanoparticles: pH Control of Structure-Property Relations.
Alison L, Demirörs AF, Tervoort E, ..., Vermant J, Studart AR
Langmuir 34 (21) 6147-6160 [2018-05-29; online 2018-05-17]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S
Nat Commun 9 (1) 2071 [2018-05-22; online 2018-05-22]
SciLifeLab Fellow
PubMed DOI Crossref
Aggregated Aβ1-42 Is Selectively Toxic for Neurons, Whereas Glial Cells Produce Mature Fibrils with Low Toxicity in Drosophila.
Jonson M, Nyström S, Sandberg A, ..., Thor S, Hammarström P
Cell Chem Biol 25 (5) 595-610.e5 [2018-05-17; online 2018-04-12]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Drug Repositioning for Effective Prostate Cancer Treatment.
Turanli B, Grøtli M, Boren J, ..., Arga KY, Mardinoglu A
Front. Physiol. 9 (-) 500 [2018-05-15; online 2018-05-15]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Mitochondrial translation efficiency controls cytoplasmic protein homeostasis.
Amunts A
- - (-) - [2018-05-14; online 2018-05-12]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Placental lncRNA Expression Is Associated With Prenatal Phthalate Exposure.
Machtinger R, Zhong J, Mansur A, ..., Karlsson O, Baccarelli AA
Toxicol Sci 163 (1) 116-122 [2018-05-01; online 2018-02-01]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells.
Pierozan P, Jerneren F, Karlsson O
Arch. Toxicol. 92 (5) 1729-1739 [2018-05-00; online 2018-03-03]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Differential susceptibility effects of oxytocin gene (OXT) polymorphisms and perceived parenting on social anxiety among adolescents.
Olofsdotter S, Åslund C, Furmark T, Comasco E, Nilsson KW
Dev Psychopathol 30 (2) 449-459 [2018-05-00; online 2017-06-13]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Novel autotrophic organisms contribute significantly to the internal carbon cycling potential of a boreal lake
Peura S, Buck M, Aalto SL, ..., Nykänen H, Eiler A
- - (-) - [2018-04-27; online 2018-04-27]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia.
Danielsson F, Fasterius E, Sullivan D, ..., Williams C, Lundberg E
Oncotarget 9 (28) 19730-19744 [2018-04-13; online 2018-04-13]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.
Amunts A
- - (-) - [2018-04-13; online 2018-04-13]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Molecular basis for voltage sensitivity in membrane proteins
Kasimova MA, Lindahl E, Delemotte L
- - (-) - [2018-04-05; online 2018-04-05]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Modular assembly of the nucleolar pre-60S ribosomal subunit.
Sanghai ZA, Miller L, Molloy KR, ..., Chait BT, Klinge S
Nature 556 (7699) 126-129 [2018-04-05; online 2018-03-05]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
An Application-Directed, Versatile DNA FISH Platform for Research and Diagnostics.
Gelali E, Custodio J, Girelli G, ..., Crosetto N, Bienko M
Methods in molecular biology (Clifton, N.J.) 1766 (-) 303-333 [2018-04-02; online 2018-04-02]
Magda Bienko SciLifeLab Fellow
DOI Crossref
Whole-Lake Sugar Addition Demonstrates Trophic Transfer of Dissolved Organic Carbon to Top Consumers
Jones RI, Kankaala P, Nykänen H, ..., Rask M, Vesala S
Ecosystems 21 (3) 495-506 [2018-04-00; online 2017-06-21]
Affiliated researcher Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor.
Perez Boerema A, Aibara S, Paul B, ..., Lindahl E, Amunts A
Nat Plants 4 (4) 212-217 [2018-04-00; online 2018-04-02]
Affiliated researcher Alexey Amunts Björn Forsberg DDLS Fellow SciLifeLab Fellow
PubMed DOI Crossref
Permeating disciplines: Overcoming barriers between molecular simulations and classical structure-function approaches in biological ion transport.
Howard RJ, Carnevale V, Delemotte L, Hellmich UA, Rothberg BS
Biochimica et Biophysica Acta (BBA) - Biomembranes 1860 (4) 927-942 [2018-04-00; online 2017-12-16]
Affiliated researcher Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Nutritional preferences of human gut bacteria reveal their metabolic idiosyncrasies.
Tramontano M, Andrejev S, Pruteanu M, ..., Typas A, Patil KR
Nat. Microbiol 3 (4) 514-522 [2018-04-00; online 2018-03-19]
Aleksej Zelezniak SciLifeLab Fellow
DOI Crossref
Learning Surrogate Models of Document Image Quality Metrics for Automated Document Image Processing
Singh P, Vats E, Hast A
- - (-) - [2018-04-00; online 2018-04-00]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Gating interaction maps reveal a noncanonical electromechanical coupling mode in the Shaker K+ channel.
Fernández-Mariño AI, Harpole TJ, Oelstrom K, Delemotte L, Chanda B
Nat. Struct. Mol. Biol. 25 (4) 320-326 [2018-04-00; online 2018-03-26]
Affiliated researcher Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4+ T Cells and Is Immunosuppressive in Type 1 Diabetes.
Bhandage AK, Jin Z, Korol SV, ..., Kamali-Moghaddam M, Birnir B
EBioMedicine 30 (-) 283-294 [2018-04-00; online 2018-03-28]
Daniel Espes SciLifeLab Fellow
PubMed DOI Crossref
Effect of Ca2+ on the promiscuous target-protein binding of calmodulin.
Westerlund AM, Delemotte L
PLoS Comput Biol 14 (4) e1006072 [2018-04-00; online 2018-04-03]
Affiliated researcher Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Conformational landscapes of membrane proteins delineated by enhanced sampling molecular dynamics simulations.
Harpole TJ, Delemotte L
Biochimica et Biophysica Acta (BBA) - Biomembranes 1860 (4) 909-926 [2018-04-00; online 2017-11-04]
Affiliated researcher Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma.
Huvila J, Laajala TD, Edqvist PH, ..., Aittokallio T, Auranen A
Gynecol. Oncol. 149 (1) 173-180 [2018-04-00; online 2018-03-02]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
DOI Crossref
Biochemical principles enabling metabolic cooperativity and phenotypic heterogeneity at the single cell level
Campbell K, Herrera-Dominguez L, Correia-Melo C, Zelezniak A, Ralser M
Current Opinion in Systems Biology 8 (-) 97-108 [2018-04-00; online 2018-04-00]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
Assembly and structure of the SSU processome-a nucleolar precursor of the small ribosomal subunit.
Barandun J, Hunziker M, Klinge S
Curr. Opin. Struct. Biol. 49 (-) 85-93 [2018-04-00; online 2018-02-04]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Targeted Long-Read Sequencing of a Locus Under Long-Term Balancing Selection in Capsella.
Bachmann JA, Tedder A, Laenen B, Steige KA, Slotte T
G3 8 (4) 1327-1333 [2018-03-28; online 2018-03-28]
Affiliated researcher SciLifeLab Fellow Tanja Slotte
DOI Crossref
Faculty Opinions recommendation of The 3.5-Å CryoEM Structure of Nanodisc-Reconstituted Yeast Vacuolar ATPase Vo Proton Channel.
Amunts A
- - (-) - [2018-03-27; online 2018-03-25]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structure of a prehandover mammalian ribosomal SRP·SRP receptor targeting complex.
Amunts A
- - (-) - [2018-03-27; online 2018-03-24]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Farming the mitochondrial ancestor as a model of endosymbiotic establishment by natural selection.
Amunts A
- - (-) - [2018-03-27; online 2018-03-26]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Suppression of diabetes by accumulation of non-islet-specific CD8 + effector T cells in pancreatic islets.
Christoffersson G, Chodaczek G, Ratliff SS, Coppieters K, von Herrath MG
Sci Immunol 3 (21) - [2018-03-23; online 2018-03-25]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Maltreatment, the Oxytocin Receptor Gene, and Conduct Problems Among Male and Female Teenagers.
Andreou D, Comasco E, Åslund C, Nilsson KW, Hodgins S
Front. Hum. Neurosci. 12 (-) 112 [2018-03-22; online 2018-03-22]
Affiliated researcher Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Authorship attribution based on Life-Like Network Automata.
Machicao J, Corrêa EA, Miranda GHB, Amancio DR, Bruno OM
PLoS ONE 13 (3) e0193703 [2018-03-22; online 2018-03-22]
Gisele Miranda SciLifeLab Fellow
PubMed DOI Crossref
Spironaphthoxazine switchable dyes for biological imaging.
Xiong Y, Vargas Jentzsch A, Osterrieth JWM, ..., Eggeling C, Anderson HL
Chem Sci 9 (11) 3029-3040 [2018-03-21; online 2018-02-20]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.
Amunts A
- - (-) - [2018-03-19; online 2018-03-11]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of A transfer-RNA-derived small RNA regulates ribosome biogenesis.
Amunts A
- - (-) - [2018-03-19; online 2018-03-11]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Non-canonical Binding Site for Bacterial Initiation Factor 3 on the Large Ribosomal Subunit.
Amunts A
- - (-) - [2018-03-16; online 2018-03-10]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Maturation of selected human mitochondrial tRNAs requires deadenylation.
Amunts A
- - (-) - [2018-03-16; online 2018-03-10]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Kinetics and mechanism of mammalian mitochondrial ribosome assembly.
Amunts A
- - (-) - [2018-03-16; online 2018-03-10]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S
Nat Commun 9 (1) 1107 [2018-03-16; online 2018-03-16]
Affiliated researcher SciLifeLab Fellow
DOI Crossref
Transcription-driven Chromatin Repression of Intragenic Promoters
Nielsen M, Ard R, Leng X, ..., Pelechano V, Marquardt S
- - (-) - [2018-03-09; online 2018-03-09]
SciLifeLab Fellow
DOI Crossref
Effect of Ca 2+ on the promiscuous target-protein binding mechanism of calmodulin
Westerlund AM, Delemotte L
- - (-) - [2018-03-07; online 2018-03-07]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.
Mardinoglu A, Wu H, Bjornson E, ..., Taskinen MR, Borén J
Cell Metab. 27 (3) 559-571.e5 [2018-03-06; online 2018-02-15]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
The neutrophil: one cell on many missions or many cells with different agendas?
Christoffersson G, Phillipson M
Cell Tissue Res. 371 (3) 415-423 [2018-03-00; online 2018-02-12]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Fluorescent Diarylethene Photoswitches-A Universal Tool for Super-Resolution Microscopy in Nanostructured Materials.
Nevskyi O, Sysoiev D, Dreier J, ..., Huhn T, Wöll D
Small 14 (10) 1703333 [2018-03-00; online 2018-01-11]
Affiliated researcher Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Contrasting patterns of genome-level diversity across distinct co-occurring bacterial populations.
Garcia SL, Stevens SLR, Crary B, ..., Malmstrom RR, McMahon KD
ISME J 12 (3) 742-755 [2018-03-00; online 2017-12-08]
Affiliated researcher Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Associations Between MAOA-uVNTR Genotype, Maltreatment, MAOA Methylation, and Alcohol Consumption in Young Adult Males.
Bendre M, Comasco E, Checknita D, ..., Hodgins S, Nilsson KW
Alcohol Clin Exp Res 42 (3) 508-519 [2018-03-00; online 2018-01-31]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Integrative Personal Omics Profiles during Periods of Weight Gain and Loss.
Piening BD, Zhou W, Contrepois K, ..., Weinstock GM, Snyder MP
Cell Systems 6 (2) 157-170.e8 [2018-02-28; online 2018-01-17]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Identification of Discriminating Metabolic Pathways and Metabolites in Human PBMCs Stimulated by Various Pathogenic Agents.
Zhang X, Mardinoglu A, Joosten LAB, ..., Netea MG, Groen AK
Front. Physiol. 9 (-) 139 [2018-02-27; online 2018-02-27]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Prediction of Ordered Water Molecules in Protein Binding Sites from Molecular Dynamics Simulations: The Impact of Ligand Binding on Hydration Networks.
Rudling A, Orro A, Carlsson J
J Chem Inf Model 58 (2) 350-361 [2018-02-26; online 2018-02-05]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Rewritable multi-event analog recording in bacterial and mammalian cells.
Elsässer S
- - (-) - [2018-02-22; online 2018-02-18]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
Interferometric scattering (iSCAT) microscopy: studies of biological membrane dynamics
Reina F, Galiani S, Shrestha D, ..., Eggeling C, Cole D
- - (-) - [2018-02-20; online 2018-02-20]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structure and conformational dynamics of the human spliceosomal bact complex.
Amunts A
- - (-) - [2018-02-19; online 2018-02-18]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Generation of Stable Amber Suppression Cell Lines.
Elsässer SJ
Methods in molecular biology (Clifton, N.J.) 1728 (-) 237-245 [2018-02-07; online 2018-02-07]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
MirGeneDB 2.0: The metazoan microRNA complement
Fromm B, Domanska D, Høye E, ..., Friedländer MR, Peterson KJ
- - (-) - [2018-02-05; online 2018-02-05]
Marc Friedländer SciLifeLab Fellow
DOI Crossref
Associations of PD-1 and PD-L1 expression with mismatch repair status and prognosis in chemoradiotherapy-naïve esophageal and gastric adenocarcinoma.
Svensson M, Borg D, Zhang C, ..., Leandersson K, Jirstrom K
J Clin Oncol 36 (4_suppl) 9-9 [2018-02-01; online 2018-02-01]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells.
Pierozan P, Karlsson O
Arch. Toxicol. 92 (2) 705-716 [2018-02-00; online 2017-10-23]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
In Vivo Visualization of β-Cells by Targeting of GPR44.
Eriksson O, Johnström P, Cselenyi Z, ..., Skrtic S, Korsgren O
Diabetes 67 (2) 182-192 [2018-02-00; online 2017-12-05]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Evaluation of Post-Mortem Effects on Global Brain DNA Methylation and Hydroxymethylation.
Sjöholm LK, Ransome Y, Ekström TJ, Karlsson O
Basic Clin. Pharmacol. Toxicol. 122 (2) 208-213 [2018-02-00; online 2017-11-13]
Oskar Karlsson SciLifeLab Fellow
DOI Crossref
Cryo-EM Reveals Molecular Transformers in Organelles
Amunts A
Biophysical Journal 114 (3) 595a [2018-02-00; online 2018-02-00]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Archaeal community changes in Lateglacial lake sediments: Evidence from ancient DNA
Ahmed E, Parducci L, Unneberg P, ..., Slotte T, Wohlfarth B
Quaternary Science Reviews 181 (-) 19-29 [2018-02-00; online 2018-02-00]
Affiliated researcher SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control.
Garg N, Hansson A, Knych HK, ..., Hedeland M, Globisch D
Org. Biomol. Chem. 16 (5) 698-702 [2018-01-31; online 2018-01-11]
Affiliated researcher Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Broad Views of Non-alcoholic Fatty Liver Disease.
Mardinoglu A, Uhlen M, Borén J
Cell Systems 6 (1) 7-9 [2018-01-24; online 2018-02-06]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Demography and mating system shape the genome-wide impact of purifying selection in Arabis alpina.
Laenen B, Tedder A, Nowak MD, ..., Coupland G, Slotte T
Proc. Natl. Acad. Sci. U.S.A. 115 (4) 816-821 [2018-01-23; online 2018-01-04]
Affiliated researcher SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Translational study reveals a two-faced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification.
Karnevi E, Dror LB, Mardinoglu A, ..., Uhlén M, Jirström K
Oncotarget 9 (5) 6188-6200 [2018-01-19; online 2017-12-15]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Consequences of Epithelial Inflammasome Activation by Bacterial Pathogens.
Sellin ME, Müller AA, Hardt WD
J. Mol. Biol. 430 (2) 193-206 [2018-01-19; online 2017-04-25]
Affiliated researcher Mikael Sellin SciLifeLab Fellow
DOI Crossref
Enhanced photon collection enables four dimensional fluorescence nanoscopy of living systems
Masullo LA, Bodén A, Pennacchietti F, ..., Ratz M, Testa I
- - (-) - [2018-01-17; online 2018-01-17]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Increased Expression of GLP-1R in Proliferating Islets of Men1 Mice is Detectable by [68Ga]Ga-DO3A-VS-Cys40-Exendin-4 /PET.
Monazzam A, Lau J, Velikyan I, ..., Eriksson O, Skogseid B
Sci Rep 8 (1) 748 [2018-01-15; online 2018-01-15]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Pausing of chloroplast ribosomes is induced by multiple features and is linked to the assembly of photosynthetic complexes.
Amunts A
- - (-) - [2018-01-11; online 2018-01-08]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Identification of oxa1 homologs operating in the eukaryotic endoplasmic reticulum.
Amunts A
- - (-) - [2018-01-11; online 2018-01-07]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of AMD1 mRNA employs ribosome stalling as a mechanism for molecular memory formation.
Amunts A
- - (-) - [2018-01-11; online 2018-01-08]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of 3D visualization of mitochondrial solid-phase calcium stores in whole cells.
Amunts A
- - (-) - [2018-01-11; online 2018-01-04]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Inference of Calmodulin's Ca2+-Dependent Free Energy Landscapes via Gaussian Mixture Model Validation.
Westerlund AM, Harpole TJ, Blau C, Delemotte L
J Chem Theory Comput 14 (1) 63-71 [2018-01-09; online 2017-12-06]
Affiliated researcher Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
TCSBN: a database of tissue and cancer specific biological networks.
Lee S, Zhang C, Arif M, ..., Uhlen M, Mardinoglu A
Nucleic Acids Res. 46 (D1) D595-D600 [2018-01-04; online 2017-10-27]
Adil Mardinoglu Affiliated researcher DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy.
Richter KN, Revelo NH, Seitz KJ, ..., Zapiec B, Rizzoli SO
EMBO J. 37 (1) 139-159 [2018-01-04; online 2017-11-16]
Affiliated researcher Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Enhancer transcription: what, where, when, and why?
Tippens ND, Vihervaara A, Lis JT
Genes Dev. 32 (1) 1-3 [2018-01-01; online 2018-02-15]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Thermodynamic analysis of computed pathways integrated into the metabolic networks of E. coli and Synechocystis reveals contrasting expansion potential.
Asplund-Samuelsson J, Janasch M, Hudson EP
Metab. Eng. 45 (-) 223-236 [2018-01-00; online 2017-12-24]
Affiliated researcher Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
The evolutionary fate of heterogeneous gene duplications: A precarious overdominant equilibrium between environment, sublethality and complementation.
Milesi P, Assogba BS, Atyame CM, ..., Weill M, Labbé P
Mol. Ecol. 27 (2) 493-507 [2018-01-00; online 2017-12-29]
Affiliated researcher Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
The environmental neurotoxin β-N-methylamino-l-alanine (l-BMAA) is deposited into birds' eggs.
Andersson M, Karlsson O, Brandt I
Ecotoxicology and Environmental Safety 147 (-) 720-724 [2018-01-00; online 2017-09-20]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Single cell genomics of uncultured marine alveolates shows paraphyly of basal dinoflagellates.
Strassert JFH, Karnkowska A, Hehenberger E, ..., Santoro AE, Keeling PJ
ISME J 12 (1) 304-308 [2018-01-00; online 2017-10-10]
Affiliated researcher Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Personality as an intermediate phenotype for genetic dissection of alcohol use disorder.
Oreland L, Lagravinese G, Toffoletto S, ..., Robert Cloninger C, Comasco E
J Neural Transm (Vienna) 125 (1) 107-130 [2018-01-00; online 2017-01-04]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4.
Eriksson O, Korsgren O, Selvaraju RK, ..., Chimienti F, Altai M
Acta diabetologica 55 (1) 49-57 [2018-01-00; online 2017-10-24]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Neurological and neuropsychological effects of low and moderate prenatal alcohol exposure.
Comasco E, Rangmar J, Eriksson UJ, Oreland L
Acta Physiol 222 (1) e12892 [2018-01-00; online 2017-05-30]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Letter: dose-response analysis revealed closer relationship between obesity and perioperative outcomes in patients after liver transplantation.
Liu Z, Mardinoglu A, Que S
Aliment. Pharmacol. Ther. 47 (2) 310-312 [2018-01-00; online 2017-12-22]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes.
Mardinoglu A, Gogg S, Lotta LA, ..., Laakso M, Smith U
EBioMedicine 27 (-) 151-155 [2018-01-00; online 2017-12-07]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Diversion of the long-chain acyl-ACP pool in Synechocystis to fatty alcohols through CRISPRi repression of the essential phosphate acyltransferase PlsX.
Kaczmarzyk D, Cengic I, Yao L, Hudson EP
Metab. Eng. 45 (-) 59-66 [2018-01-00; online 2017-12-02]
Affiliated researcher Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Divergence of a Tandem Duplication of Manganese Superoxide Dismutase in Nosema bombycis.
Wang Y, Zhang R, Barandun J, ..., Vossbrinck CR, Xiang H
J. Eukaryot. Microbiol. 65 (1) 93-103 [2018-01-00; online 2017-08-07]
Jonas Barandun SciLifeLab Fellow
DOI Crossref
Network Analysis Reveals Heterogeneous Response of Redox Metabolism in Hepatocellular Carcinoma Patients
Benfeitas R, Bidkhori G, Mukhopadhyay B, ..., Kunos G, Mardinoglu A
SSRN Journal - (-) - [2018-00-00; online 2018-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
An Organ-Wide Gene Expression Atlas of the Developing Human Heart
Asp M, Giacomello S, Fürth D, ..., Sylvén C, Lundeberg J
SSRN Journal - (-) - [2018-00-00; online 2018-00-00]
Daniel Fürth Magda Bienko SciLifeLab Fellow

Year 2017

PubMed DOI Crossref
Normal values for calprotectin in stool samples of infants from the population-based longitudinal born into life study.
Peura S, Fall T, Almqvist C, ..., Helmersson-Karlqvist J, Larsson A
Scandinavian Journal of Clinical and Laboratory Investigation 78 (1-2) 120-124 [2017-12-28; online 2017-12-28]
Affiliated researcher Sari Peura SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of The complete structure of the small-subunit processome.
Amunts A
- - (-) - [2017-12-21; online 2017-12-17]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of The ER membrane protein complex is a transmembrane domain insertase.
Amunts A
- - (-) - [2017-12-21; online 2017-12-17]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Novel Trimodal MALDI Imaging Mass Spectrometry (IMS3) at 10 μm Reveals Spatial Lipid and Peptide Correlates Implicated in Aβ Plaque Pathology in Alzheimer's Disease.
Kaya I, Brinet D, Michno W, ..., Blenow K, Hanrieder J
ACS Chem Neurosci 8 (12) 2778-2790 [2017-12-20; online 2017-10-04]
SciLifeLab Fellow Wojciech Michno
DOI Crossref
Faculty Opinions recommendation of Structural basis of proton translocation and force generation in mitochondrial ATP synthase.
Amunts A
- - (-) - [2017-12-20; online 2017-12-17]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of A semi-synthetic organism that stores and retrieves increased genetic information.
Elsässer S
- - (-) - [2017-12-11; online 2017-12-04]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1.
Lehmann LC, Hewitt G, Aibara S, ..., Boulton SJ, Deindl S
Mol. Cell 68 (5) 847-859.e7 [2017-12-07; online 2017-12-09]
Affiliated researcher Emil Marklund SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method.
Plum J, Madsen CM, Teleki A, ..., Rades T, Müllertz A
Mol. Pharm. 14 (12) 4161-4169 [2017-12-04; online 2017-11-07]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
A New Lineage of Eukaryotes Illuminates Early Mitochondrial Genome Reduction.
Janouškovec J, Tikhonenkov DV, Burki F, ..., Mylnikov AP, Keeling PJ
Curr. Biol. 27 (23) 3717-3724.e5 [2017-12-04; online 2017-11-22]
Affiliated researcher Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Rational Synthesis of 2-Bromoporphyrins and 2,12-Dibromoporphyrins.
Bornhof AB, Xiong R, Borbas KE
J. Org. Chem. 82 (23) 12908-12913 [2017-12-01; online 2017-11-15]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
COMT genotype and non-recovery after a whiplash injury in a Northern European population.
Rydman E, Comasco E, Pettersson H, ..., Ponzer S, Ottosson C
BMC Musculoskelet Disord 18 (1) 507 [2017-12-01; online 2017-12-01]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Surrogate assisted model reduction for stochastic biochemical reaction networks
Singh P, Hellander A
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Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
From transcriptional complexity to cellular phenotypes: Lessons from yeast.
Pelechano V
Yeast 34 (12) 475-482 [2017-12-00; online 2017-10-11]
Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Evolution of epigenetic chromatin states.
Yung PYK, Elsässer SJ
Curr Opin Chem Biol 41 (-) 36-42 [2017-12-00; online 2017-11-02]
Affiliated researcher SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Biodiversity, drug discovery, and the future of global health: Introducing the biodiversity to biomedicine consortium, a call to action.
Neergheen-Bhujun V, Awan AT, Baran Y, ..., Pešić M, Kagansky A
Journal of global health 7 (2) 020304 [2017-12-00; online 2018-01-06]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
An essential regulatory function of the DnaK chaperone dictates the decision between proliferation and maintenance in Caulobacter crescentus.
Schramm FD, Heinrich K, Thüring M, Bernhardt J, Jonas K
PLoS Genet 13 (12) e1007148 [2017-12-00; online 2017-12-27]
Affiliated researcher Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
HDL particles incorporate into lipid bilayers - a combined AFM and single molecule fluorescence microscopy study.
Plochberger B, Röhrl C, Preiner J, ..., Stangl H, Schütz GJ
Sci Rep 7 (1) 15886 [2017-11-21; online 2017-11-21]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity.
Ernst C, Odom DT, Kutter C
Nat Commun 8 (1) 1411 [2017-11-10; online 2017-11-10]
Affiliated researcher Claudia Kutter SciLifeLab Fellow
DOI Crossref
Automatic Document Image Binarization using Bayesian Optimization
Vats E, Hast A, Singh P
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Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Ribosome origami.
Rorbach J, Aibara S, Amunts A
Nat. Struct. Mol. Biol. 24 (11) 879-881 [2017-11-07; online 2017-11-08]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Cryo-EM reconstruction of the chlororibosome to 3.2 Å resolution within 24 h.
Forsberg BO, Aibara S, Kimanius D, ..., Lindahl E, Amunts A
IUCrJ 4 (Pt 6) 723-727 [2017-11-01; online 2017-09-22]
Alexey Amunts Björn Forsberg DDLS Fellow SciLifeLab Fellow
PubMed DOI Crossref
The complete structure of the small-subunit processome.
Barandun J, Chaker-Margot M, Hunziker M, ..., Chait BT, Klinge S
Nat. Struct. Mol. Biol. 24 (11) 944-953 [2017-11-00; online 2017-09-25]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
The acute effects of ultraviolet radiation on the blood transcriptome are independent of plasma 25OHD3.
Bustamante M, Hernandez-Ferrer C, Sarria Y, ..., Nieuwenhuijsen M, Young AR
Environ. Res. 159 (-) 239-248 [2017-11-00; online 2017-09-18]
Affiliated researcher Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Species differences in pancreatic binding of DO3A-VS-Cys 40-Exendin4.
Eriksson O, Rosenström U, Selvaraju RK, Eriksson B, Velikyan I
Acta diabetologica 54 (11) 1039-1045 [2017-11-00; online 2017-09-11]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Constrained multi-objective antenna design optimization using surrogates
Singh P, Rossi M, Couckuyt I, ..., Rogier H, Dhaene T
Int J Numer Model 30 (6) e2248 [2017-11-00; online 2017-05-04]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
In situ metabolomic- and transcriptomic-profiling of the host-associated cyanobacteria Prochloron and Acaryochloris marina.
Behrendt L, Raina JB, Lutz A, ..., Larkum AW, Kühl M
ISME J 12 (2) 556-567 [2017-10-31; online 2017-10-31]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Studying Kv Channels Function using Computational Methods.
Deyawe A, Kasimova MA, Delemotte L, Loussouarn G, Tarek M
Methods in molecular biology (Clifton, N.J.) 1684 (-) 321-341 [2017-10-24; online 2017-10-24]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Structure-Guided Screening for Functionally Selective D2 Dopamine Receptor Ligands from a Virtual Chemical Library.
Männel B, Jaiteh M, Zeifman A, ..., Gmeiner P, Carlsson J
ACS chemical biology 12 (10) 2652-2661 [2017-10-20; online 2017-09-19]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Genome-Wide Profiling of DNA Double-Strand Breaks by the BLESS and BLISS Methods.
Mirzazadeh R, Kallas T, Bienko M, Crosetto N
Methods in molecular biology (Clifton, N.J.) 1672 (-) 167-194 [2017-10-19; online 2017-10-19]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Multiplexed ChIP-Seq Using Direct Nucleosome Barcoding: A Tool for High-Throughput Chromatin Analysis.
Chabbert CD, Adjalley SH, Steinmetz LM, Pelechano V
Methods in molecular biology (Clifton, N.J.) 1689 (-) 177-194 [2017-10-14; online 2017-10-14]
SciLifeLab Fellow
PubMed DOI Crossref
Signatures of positive selection reveal a universal role of chromatin modifiers as cancer driver genes.
Zapata L, Susak H, Drechsel O, ..., Estivill X, Ossowski S
Sci Rep 7 (1) 13124 [2017-10-13; online 2017-10-13]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space.
Rudling A, Gustafsson R, Almlöf I, ..., Stenmark P, Carlsson J
J Med Chem 60 (19) 8160-8169 [2017-10-12; online 2017-10-03]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Spatial detection of fetal marker genes expressed at low level in adult human heart tissue.
Asp M, Salmén F, Ståhl PL, ..., Linde C, Lundeberg J
Sci Rep 7 (1) 12941 [2017-10-11; online 2017-10-11]
Affiliated researcher Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Gating Pore Currents in Sodium Channels.
Groome JR, Moreau A, Delemotte L
Handb Exp Pharmacol 246 (-) 371-399 [2017-10-02; online 2017-10-02]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
The Role of Small RNA-Based Epigenetic Silencing for Purifying Selection on Transposable Elements in Capsella grandiflora.
Horvath R, Slotte T
Genome Biol Evol 9 (10) 2911-2920 [2017-10-01; online 2017-10-17]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Differential Impact of Glucose Administered Intravenously and Orally on Circulating miR-375 Levels in Human Subjects.
Yan X, Wang Z, Westberg-Rasmussen S, ..., Gregersen S, Poy MN
J. Clin. Endocrinol. Metab. 102 (10) 3749-3755 [2017-10-01; online 2017-10-04]
Affiliated researcher DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
PubMed DOI Crossref
The tyrosine Y2502.39 in Frizzled 4 defines a conserved motif important for structural integrity of the receptor and recruitment of Disheveled.
Strakova K, Matricon P, Yokota C, ..., Bryja V, Schulte G
Cell. Signal. 38 (-) 85-96 [2017-10-00; online 2017-06-29]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Structures of the human mitochondrial ribosome in native states of assembly.
Brown A, Rathore S, Kimanius D, ..., Amunts A, Ramakrishnan V
Nat. Struct. Mol. Biol. 24 (10) 866-869 [2017-10-00; online 2017-09-11]
Affiliated researcher Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Rediscussion on linearity between fibrosis stages and mortality risk in nonalcoholic fatty liver disease patients.
Liu Z, Que S, Mardinoglu A
Hepatology 66 (4) 1357-1358 [2017-10-00; online 2017-09-04]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Multi-objective Geometry Optimization of a Gas Cyclone Using Triple-Fidelity Co-Kriging Surrogate Models
Singh P, Couckuyt I, Elsayed K, Deschrijver D, Dhaene T
J Optim Theory Appl 175 (1) 172-193 [2017-10-00; online 2017-05-10]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Maternal and female fetal testosterone levels are associated with maternal age and gestational weight gain.
Kallak TK, Hellgren C, Skalkidou A, ..., Campbell RE, Sundström Poromaa I
Eur. J. Endocrinol. 177 (4) 379-388 [2017-10-00; online 2017-07-13]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Improving the economics of NASH/NAFLD treatment through the use of systems biology.
Bosley J, Boren C, Lee S, ..., Boren J, Mardinoglu A
Drug Discov. Today 22 (10) 1532-1538 [2017-10-00; online 2017-07-20]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans.
Nylander I, Todkar A, Granholm L, ..., Nilsson KW, Comasco E
Mol. Neurobiol. 54 (8) 6225-6234 [2017-10-00; online 2016-10-05]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus.
Matzov D, Aibara S, Basu A, ..., Amunts A, Yonath AE
Nat Commun 8 (1) 723 [2017-09-28; online 2017-09-28]
Affiliated researcher Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation.
Gómez-Herreros F, Margaritis T, Rodríguez-Galán O, ..., Holstege FCP, Chávez S
Nucleic Acids Res. 45 (16) 9302-9318 [2017-09-19; online 2017-06-24]
Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Polarity-Sensitive Probes for Superresolution Stimulated Emission Depletion Microscopy.
Sezgin E, Schneider F, Zilles V, ..., Klymchenko AS, Eggeling C
Biophys. J. 113 (6) 1321-1330 [2017-09-19; online 2017-07-19]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Vascular sprouts induce local attraction of proangiogenic neutrophils.
Christoffersson G, Lomei J, O'Callaghan P, ..., Engblom S, Phillipson M
J Leukoc Biol 102 (3) 741-751 [2017-09-00; online 2017-06-05]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Metformin treatment significantly enhances intestinal glucose uptake in patients with type 2 diabetes: Results from a randomized clinical trial.
Koffert JP, Mikkola K, Virtanen KA, ..., Gomez MF, Nuutila P
Diabetes Res. Clin. Pract. 131 (-) 208-216 [2017-09-00; online 2017-07-20]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Metabolic Network Analysis and Metatranscriptomics Reveal Auxotrophies and Nutrient Sources of the Cosmopolitan Freshwater Microbial Lineage acI.
Hamilton JJ, Garcia SL, Brown BS, ..., Forest KT, McMahon KD
mSystems 2 (4) - [2017-08-29; online 2017-08-29]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
The effect of the TM6SF2 E167K variant on liver steatosis and fibrosis in patients with chronic hepatitis C: a meta-analysis.
Liu Z, Que S, Zhou L, ..., Mardinoglu A, Valenti L
Sci Rep 7 (1) 9273 [2017-08-24; online 2017-08-24]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Network analyses identify liver-specific targets for treating liver diseases.
Lee S, Zhang C, Liu Z, ..., Boren J, Mardinoglu A
Mol Syst Biol 13 (8) 938 [2017-08-21; online 2017-08-21]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
A pathology atlas of the human cancer transcriptome.
Uhlen M, Zhang C, Lee S, ..., Mardinoglu A, Ponten F
Science (New York, N.Y.) 357 (6352) eaan2507 [2017-08-18; online 2017-08-19]
Adil Mardinoglu Affiliated researcher DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Transcriptional response to stress is pre-wired by promoter and enhancer architecture.
Vihervaara A, Mahat DB, Guertin MJ, ..., Lis JT, Sistonen L
Nat Commun 8 (1) 255 [2017-08-15; online 2017-08-15]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling.
Petersen J, Wright SC, Rodríguez D, ..., Carlsson J, Schulte G
Nat Commun 8 (1) 226 [2017-08-09; online 2017-08-09]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Elsässer et al. reply.
Elsässer SJ, Noh KM, Diaz N, Allis CD, Banaszynski LA
Nature 548 (7665) E7-E9 [2017-08-02; online 2017-08-05]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG).
Globisch D, Eubanks LM, Shirey RJ, ..., Hoerauf A, Janda KD
Bioorg. Med. Chem. Lett. 27 (15) 3436-3440 [2017-08-01; online 2017-05-29]
Affiliated researcher Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
The expression of opioid genes in non-classical reward areas depends on early life conditions and ethanol intake.
Granholm L, Todkar A, Bergman S, ..., Comasco E, Nylander I
Brain Res 1668 (-) 36-45 [2017-08-01; online 2017-05-13]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease.
Mardinoglu A, Stančáková A, Lotta LA, ..., Langenberg C, Smith U
Cell Metab. 26 (2) 281-283 [2017-08-01; online 2017-08-03]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Vimentin deficiency in macrophages induces CD36-mediated inflammation
Håversen L, Ståhlman M, Mattson Hultén L, ..., Levin M, Borén J
Atherosclerosis 263 (-) e87-e88 [2017-08-00; online 2017-08-00]
Adil Mardinoglu SciLifeLab Fellow
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Poorly known microbial taxa dominate the microbiome of permafrost thaw ponds.
Wurzbacher C, Nilsson RH, Rautio M, Peura S
ISME J 11 (8) 1938-1941 [2017-08-00; online 2017-04-21]
Affiliated researcher Sari Peura SciLifeLab Fellow
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Heterogeneous gene duplications can be adaptive because they permanently associate overdominant alleles.
Milesi P, Weill M, Lenormand T, Labbé P
Evol Lett 1 (3) 169-180 [2017-08-00; online 2017-07-21]
Pascal Milesi SciLifeLab Fellow
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Binding of canonical Wnt ligands to their receptor complexes occurs in ordered plasma membrane environments.
Sezgin E, Azbazdar Y, Ng XW, ..., Eggeling C, Ozhan G
FEBS J. 284 (15) 2513-2526 [2017-08-00; online 2017-07-06]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Allopregnanolone levels and depressive symptoms during pregnancy in relation to single nucleotide polymorphisms in the allopregnanolone synthesis pathway.
Hellgren C, Comasco E, Skalkidou A, Sundström-Poromaa I
Horm Behav 94 (-) 106-113 [2017-08-00; online 2017-07-20]
Erika Comasco SciLifeLab Fellow
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A Biopsychosocial Approach to Risk and Resilience on Behavior in Children Followed from Birth to Age 12.
Agnafors S, Svedin CG, Oreland L, ..., Comasco E, Sydsjö G
Child Psychiatry Hum Dev 48 (4) 584-596 [2017-08-00; online 2016-09-16]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Molecular simulations and free-energy calculations suggest conformation-dependent anion binding to a cytoplasmic site as a mechanism for Na+/K+-ATPase ion selectivity.
Razavi AM, Delemotte L, Berlin JR, Carnevale V, Voelz VA
J Biol Chem 292 (30) 12412-12423 [2017-07-28; online 2017-06-06]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Fragment optimization for GPCRs by molecular dynamics free energy calculations: Probing druggable subpockets of the A 2A adenosine receptor binding site.
Matricon P, Ranganathan A, Warnick E, ..., Jacobson KA, Carlsson J
Sci Rep 7 (1) 6398 [2017-07-25; online 2017-07-25]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed
Fully automated GMP production of [68Ga]Ga-DO3A-VS-Cys40-Exendin-4 for clinical use.
Velikyan I, Rosenstrom U, Eriksson O
American journal of nuclear medicine and molecular imaging 7 (3) 111-125 [2017-07-15; online 2017-07-15]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Combined PET and microdialysis for in vivo estimation of drug blood-brain barrier transport and brain unbound concentrations.
Gustafsson S, Eriksson J, Syvänen S, ..., Hammarlund-Udenaes M, Antoni G
NeuroImage 155 (-) 177-186 [2017-07-15; online 2017-04-30]
Olof Eriksson SciLifeLab Fellow
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Super-resolution optical microscopy for studying membrane structure and dynamics.
Sezgin E
J Phys Condens Matter 29 (27) 273001 [2017-07-12; online 2017-05-08]
Erdinc Sezgin SciLifeLab Fellow
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New Challenges to Study Heterogeneity in Cancer Redox Metabolism.
Benfeitas R, Uhlen M, Nielsen J, Mardinoglu A
Front Cell Dev Biol 5 (-) 65 [2017-07-11; online 2017-07-11]
Adil Mardinoglu SciLifeLab Fellow
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The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization.
Alam MT, Olin-Sandoval V, Stincone A, ..., Luisi BF, Ralser M
Nat Commun 8 (-) 16018 [2017-07-10; online 2017-07-10]
Aleksej Zelezniak SciLifeLab Fellow
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eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences.
Pelechano V, Alepuz P
Nucleic Acids Res. 45 (12) 7326-7338 [2017-07-07; online 2017-05-27]
Affiliated researcher SciLifeLab Fellow
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Effects of alternative electron acceptors on the activity and community structure of methane-producing and consuming microbes in the sediments of two shallow boreal lakes.
Rissanen AJ, Karvinen A, Nykänen H, ..., Mäki A, Kankaala P
FEMS Microbiol. Ecol. 93 (7) - [2017-07-01; online 2017-06-24]
Affiliated researcher Sari Peura SciLifeLab Fellow
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Toward molecular imaging of the free fatty acid receptor 1.
Hellström-Lindahl E, Åberg O, Ericsson C, ..., Skrtic S, Eriksson O
Acta diabetologica 54 (7) 663-668 [2017-07-00; online 2017-04-13]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
MALDI imaging delineates hippocampal glycosphingolipid changes associated with neurotoxin induced proteopathy following neonatal BMAA exposure.
Karlsson O, Michno W, Ransome Y, Hanrieder J
Biochim Biophys Acta Proteins Proteom 1865 (7) 740-746 [2017-07-00; online 2016-12-09]
Oskar Karlsson SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome.
Diepold A, Sezgin E, Huseyin M, ..., Eggeling C, Armitage JP
Nat Commun 8 (-) 15940 [2017-06-27; online 2017-06-27]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Diffusion of lipids and GPI-anchored proteins in actin-free plasma membrane vesicles measured by STED-FCS.
Schneider F, Waithe D, Clausen MP, ..., Eggeling C, Sezgin E
Mol. Biol. Cell 28 (11) 1507-1518 [2017-06-01; online 2017-04-12]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
The mystery of membrane organization: composition, regulation and roles of lipid rafts.
Sezgin E, Levental I, Mayor S, Eggeling C
Nat. Rev. Mol. Cell Biol. 18 (6) 361-374 [2017-06-00; online 2017-03-30]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Structural Variation Detection with Read Pair Information: An Improved Null Hypothesis Reduces Bias.
Sahlin K, Frånberg M, Arvestad L
J. Comput. Biol. 24 (6) 581-589 [2017-06-00; online 2016-09-28]
Affiliated researcher Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
A subcellular map of the human proteome.
Thul PJ, Åkesson L, Wiking M, ..., Uhlén M, Lundberg E
Science (New York, N.Y.) 356 (6340) eaal3321 [2017-05-26; online 2017-05-11]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
DOI Crossref
Novel chemolithotrophic and anoxygenic phototrophic genomes extracted from ice-covered boreal lakes
Sinclair L, Peura S, Hernández P, Schattenhofer M, Eiler A
- - (-) - [2017-05-17; online 2017-05-17]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Multifractal and mechanical analysis of amorphous solid dispersions.
Adler C, Teleki A, Kuentz M
Int J Pharm 523 (1) 91-101 [2017-05-15; online 2017-03-09]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Spectral imaging toolbox: segmentation, hyperstack reconstruction, and batch processing of spectral images for the determination of cell and model membrane lipid order.
Aron M, Browning R, Carugo D, ..., Eggeling C, Stride E
BMC Bioinformatics 18 (1) 254 [2017-05-12; online 2017-05-12]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks.
Yan WX, Mirzazadeh R, Garnerone S, ..., Bienko M, Crosetto N
Nat Commun 8 (1) 15058 [2017-05-12; online 2017-05-12]
Affiliated researcher Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Phase Partitioning of GM1 and Its Bodipy-Labeled Analog Determine Their Different Binding to Cholera Toxin.
Rissanen S, Grzybek M, Orłowski A, ..., Sezgin E, Vattulainen I
Front. Physiol. 8 (-) 252 [2017-05-09; online 2017-05-09]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Spatially resolved transcriptome profiling in model plant species.
Giacomello S, Salmén F, Terebieniec BK, ..., Street NR, Lundeberg J
Nat Plants 3 (-) 17061 [2017-05-08; online 2017-05-08]
Affiliated researcher Sanja Vickovic SciLifeLab Fellow
DOI Crossref
Demography and mating system shape the genome-wide impact of purifying selection in Arabis alpina
Laenen B, Tedder A, Nowak MD, ..., Coupland G, Slotte T
- - (-) - [2017-05-04; online 2017-05-04]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
[ 11C]5-hydroxy-tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes.
Carlbom L, Espes D, Lubberink M, ..., Korsgren O, Eriksson O
Diabetes 66 (5) 1286-1292 [2017-05-00; online 2017-02-28]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
High-avidity IgA protects the intestine by enchaining growing bacteria.
Moor K, Diard M, Sellin ME, ..., Hardt WD, Slack E
Nature 544 (7651) 498-502 [2017-04-27; online 2017-04-12]
Affiliated researcher Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Does Proton Conduction in the Voltage-Gated H+ Channel hHv1 Involve Grotthuss-Like Hopping via Acidic Residues?
van Keulen SC, Gianti E, Carnevale V, ..., Rothlisberger U, Delemotte L
J Phys Chem B 121 (15) 3340-3351 [2017-04-20; online 2016-11-18]
Affiliated researcher Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Histology-Compatible MALDI Mass Spectrometry Based Imaging of Neuronal Lipids for Subsequent Immunofluorescent Staining.
Kaya I, Michno W, Brinet D, ..., Zetterberg H, Hanrieder J
Anal. Chem. 89 (8) 4685-4694 [2017-04-18; online 2017-04-06]
SciLifeLab Fellow Wojciech Michno
DOI Crossref
Bayesian inference of cancer driver genes using signatures of positive selection
Zapata L, Susak H, Drechsel O, ..., Estivill X, Ossowski S
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Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
A Fluorophore Fusion Construct of Human Profilin I with Non-Compromised Poly(L-Proline) Binding Capacity Suitable for Imaging.
Nejedla M, Li Z, Masser AE, ..., Friedländer MR, Karlsson R
J. Mol. Biol. 429 (7) 964-976 [2017-04-07; online 2017-01-08]
Affiliated researcher Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Laurdan and Di-4-ANEPPDHQ probe different properties of the membrane.
Amaro M, Reina F, Hof M, Eggeling C, Sezgin E
J. Phys. D: Appl. Phys. 50 (13) 134004 [2017-04-05; online 2017-03-07]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts.
Kang W, Bang-Berthelsen CH, Holm A, ..., Estivill X, Friedländer MR
RNA 23 (4) 433-445 [2017-04-00; online 2017-01-06]
Affiliated researcher Marc Friedländer SciLifeLab Fellow
DOI Crossref
Automated Line-Based Sequential Sampling and Modeling Algorithm for EMC Near-Field Scanning
Singh P, Claeys T, Vandenbosch GAE, Pissoort D
IEEE Trans. Electromagn. Compat. 59 (2) 704-709 [2017-04-00; online 2017-04-00]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
AUP1 (Ancient Ubiquitous Protein 1): A Molecular Link Between Hepatic Lipid Mobilization and VLDL Secretion.
Mardinoglu A, Borén J
Arterioscler. Thromb. Vasc. Biol. 37 (4) 609-610 [2017-04-00; online 2017-03-24]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
A sequential sampling strategy for adaptive classification of computationally expensive data
Singh P, Herten Jvd, Deschrijver D, Couckuyt I, Dhaene T
Struct Multidisc Optim 55 (4) 1425-1438 [2017-04-00; online 2016-09-22]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Electroformation of Giant Unilamellar Vesicles on Stainless Steel Electrodes.
Pereno V, Carugo D, Bau L, ..., Eggeling C, Stride E
ACS Omega 2 (3) 994-1002 [2017-03-31; online 2017-03-16]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Furan- and Thiophene-Based Auxochromes Red-shift Chlorin Absorptions and Enable Oxidative Chlorin Polymerizations.
Xiong R, Bornhof AB, Arkhypchuk AI, Orthaber A, Borbas KE
Chemistry 23 (17) 4089-4095 [2017-03-23; online 2017-01-23]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Quantification of HER2 and estrogen receptor heterogeneity in breast cancer by single-molecule RNA fluorescence in situ hybridization.
Annaratone L, Simonetti M, Wernersson E, ..., Sapino A, Crosetto N
Oncotarget 8 (12) 18680-18698 [2017-03-21; online 2017-04-21]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Ligand Discovery for a Peptide-Binding GPCR by Structure-Based Screening of Fragment- and Lead-Like Chemical Libraries.
Ranganathan A, Heine P, Rudling A, ..., Kummer L, Carlsson J
ACS chemical biology 12 (3) 735-745 [2017-03-17; online 2017-01-24]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Inflammation boosts bacteriophage transfer between Salmonella spp.
Diard M, Bakkeren E, Cornuault JK, ..., Slack E, Hardt WD
Science (New York, N.Y.) 355 (6330) 1211-1215 [2017-03-17; online 2017-03-16]
Affiliated researcher Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Emotional anticipation after delivery - a longitudinal neuroimaging study of the postpartum period.
Gingnell M, Toffoletto S, Wikström J, ..., Comasco E, Sundström-Poromaa I
Sci Rep 7 (1) 114 [2017-03-08; online 2017-03-08]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD.
Mardinoglu A, Bjornson E, Zhang C, ..., Taskinen MR, Boren J
Mol Syst Biol 13 (3) 916 [2017-03-02; online 2017-03-02]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Ethanol affects limbic and striatal presynaptic glutamatergic and DNA methylation gene expression in outbred rats exposed to early-life stress.
Vrettou M, Granholm L, Todkar A, ..., Nylander I, Comasco E
Addict Biol 22 (2) 369-380 [2017-03-00; online 2015-11-27]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Development of a novel therapeutic vaccine carrier that sustains high antibody titers against several targets simultaneously.
Saupe F, Reichel M, Huijbers EJ, ..., Hellman LT, Olsson AK
FASEB J. 31 (3) 1204-1214 [2017-03-00; online 2016-12-19]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
05.16 Transcriptome visualisation of the inflamed rheumatoid arthritis joint
Carlberg K, Vickovic S, Ståhl PL, ..., Malmström V, Lundeberg J
Ann Rheum Dis 76 (-) A58-A59 [2017-03-00; online 2017-03-00]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease.
Borroto-Escuela DO, Carlsson J, Ambrogini P, ..., Diaz-Cabiale Z, Fuxe K
Front. Cell. Neurosci. 11 (-) 37 [2017-02-21; online 2017-02-21]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Delineating Amyloid Plaque Associated Neuronal Sphingolipids in Transgenic Alzheimer's Disease Mice (tgArcSwe) Using MALDI Imaging Mass Spectrometry.
Kaya I, Brinet D, Michno W, ..., Blennow K, Hanrieder J
ACS Chem Neurosci 8 (2) 347-355 [2017-02-15; online 2017-01-10]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Genetic and Functional Study of L-Type Amino Acid Transporter 1 in Schizophrenia.
Comasco E, Vumma R, Toffoletto S, ..., Jönsson EG, Venizelos N
Neuropsychobiology 74 (2) 96-103 [2017-02-11; online 2017-02-11]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Free energy calculations suggest a mechanism for Na+/K+-ATPase ion selectivity
Razavi AM, Delemotte L, Berlin JR, Carnevale V, Voelz VA
- - (-) - [2017-02-07; online 2017-02-07]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
The structure of the yeast mitochondrial ribosome.
Desai N, Brown A, Amunts A, Ramakrishnan V
Science (New York, N.Y.) 355 (6324) 528-531 [2017-02-03; online 2017-02-06]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Prokaryotic ubiquitin-like protein remains intrinsically disordered when covalently attached to proteasomal target proteins.
Barandun J, Damberger FF, Delley CL, ..., Allain FH, Weber-Ban E
BMC Struct. Biol. 17 (1) 1 [2017-02-01; online 2017-02-01]
Jonas Barandun SciLifeLab Fellow
DOI Crossref
RESOLFT Optical Nanoscopy for the Life Sciences
Testa I
Biophysical Journal 112 (3) 7a [2017-02-00; online 2017-02-00]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Multifractal Characterization of Pharmaceutical Hot-Melt Extrudates.
Adler C, Teleki A, Kuentz M
Pharm. Res. 34 (2) 321-332 [2017-02-00; online 2016-11-14]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
Does Proton Conduction in the Voltage-Gated Proton Channel hH V 1 Involve Grotthus Hopping via Acidic Residues?
Delemotte L, van Keulen S, Roethlisberger U, ..., Carnevale V, Klein ML
Biophysical Journal 112 (3) 163a-164a [2017-02-00; online 2017-02-00]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Predicting growth of the healthy infant using a genome scale metabolic model.
Nilsson A, Mardinoglu A, Nielsen J
NPJ Syst Biol Appl 3 (1) 3 [2017-01-31; online 2017-01-31]
Adil Mardinoglu Avlant Nilsson SciLifeLab Fellow
PubMed DOI Crossref
Genomic analysis reveals major determinants of cis-regulatory variation in Capsella grandiflora.
Steige KA, Laenen B, Reimegård J, Scofield DG, Slotte T
Proc. Natl. Acad. Sci. U.S.A. 114 (5) 1087-1092 [2017-01-31; online 2017-01-17]
Affiliated researcher SciLifeLab Fellow Tanja Slotte
DOI Crossref
Model communities hint to promiscuous metabolic linkages between ubiquitous free-living freshwater bacteria
Garcia SL, Buck M, Hamilton JJ, ..., Warnecke F, Eiler A
- - (-) - [2017-01-28; online 2017-01-28]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Vimentin Levels and Serine 71 Phosphorylation in the Control of Cell-Matrix Adhesions, Migration Speed, and Shape of Transformed Human Fibroblasts.
Terriac E, Coceano G, Mavajian Z, ..., Lautenschläger F, Gad AK
Cells 6 (1) 2 [2017-01-22; online 2017-01-22]
Affiliated researcher Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Affibody Scaffolds Improve Sesquiterpene Production in Saccharomyces cerevisiae.
Tippmann S, Anfelt J, David F, ..., Nielsen J, Hudson EP
ACS Synth. Biol. 6 (1) 19-28 [2017-01-20; online 2016-08-30]
Affiliated researcher Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging.
Zanni G, Michno W, Di Martino E, ..., Blomgren K, Hanrieder J
Sci Rep 7 (-) 40726 [2017-01-18; online 2017-01-18]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Architecture of the yeast small subunit processome.
Chaker-Margot M, Barandun J, Hunziker M, Klinge S
Science 355 (6321) - [2017-01-13; online 2016-12-15]
Jonas Barandun SciLifeLab Fellow
DOI Crossref
Rituximab capping triggers intracellular reorganization of B cells
Koller T, Blok S, Santos AM, ..., Sezgin E, Eggeling C
Matters - (-) - [2017-01-12; online 2017-01-12]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Major transitions in dinoflagellate evolution unveiled by phylotranscriptomics.
Janouškovec J, Gavelis GS, Burki F, ..., Rohwer FL, Saldarriaga JF
Proc. Natl. Acad. Sci. U.S.A. 114 (2) E171-E180 [2017-01-10; online 2016-12-27]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Sex differences in depression during pregnancy and the postpartum period.
Sundström Poromaa I, Comasco E, Georgakis MK, Skalkidou A
J Neurosci Res 95 (1-2) 719-730 [2017-01-02; online 2016-11-22]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Associations between a polymorphism in the hydroxysteroid (11-beta) dehydrogenase 1 gene, neuroticism and postpartum depression.
Iliadis SI, Comasco E, Hellgren C, ..., Sundström Poromaa I, Skalkidou A
J Affect Disord 207 (-) 141-147 [2017-01-01; online 2016-09-26]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Modulation of the molecular arrangement in artificial and biological membranes by phospholipid-shelled microbubbles.
Carugo D, Aron M, Sezgin E, ..., Eggeling C, Stride E
Biomaterials 113 (-) 105-117 [2017-01-00; online 2016-10-24]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity: a study of young healthy MZ twins.
Heinonen S, Muniandy M, Buzkova J, ..., Rissanen A, Pietiläinen KH
Diabetologia 60 (1) 169-181 [2017-01-00; online 2016-10-12]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
DOI Crossref
The Convoluted Evolution of Eukaryotes With Complex Plastids
Burki F
- - (-) 1-30 [2017-00-00; online 2017-00-00]
Affiliated researcher Fabien Burki SciLifeLab Fellow
DOI Crossref
Structure-Based Discovery of GPCR Ligands from Crystal Structures and Homology Models
Ranganathan A, Rodríguez D, Carlsson J
- - (-) 65-99 [2017-00-00; online 2017-05-25]
Jens Carlsson SciLifeLab Fellow
DOI Crossref
Long Non Coding RNA Biology
Springer [book] (-) - [2017-00-00; online 2017-00-00]
SciLifeLab Fellow Vicente Pelechano
DOI Crossref
Evolution of Resistance to Insecticide in Disease Vectors
Labbé P, David JP, Alout H, ..., Pasteur N, Weill M
- - (-) 313-339 [2017-00-00; online 2017-00-00]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
Bridging chemical- and bio-catalysis: high-value liquid transportation fuel production from renewable agricultural residues
Xue C, Liu M, Guo X, ..., Liu F, Yang ST
Green Chem. 19 (3) 660-669 [2017-00-00; online 2017-00-00]
Paul Hudson SciLifeLab Fellow

Year 2016

PubMed DOI Crossref
The Chd1 chromatin remodeler shifts hexasomes unidirectionally.
Levendosky RF, Sabantsev A, Deindl S, Bowman GD
Elife 5 (-) - [2016-12-29; online 2016-12-29]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
Author response: The Chd1 chromatin remodeler shifts hexasomes unidirectionally
Levendosky RF, Sabantsev A, Deindl S, Bowman GD
- - (-) - [2016-12-28; online 2016-12-28]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
On the role of water density fluctuations in the inhibition of a proton channel.
Gianti E, Delemotte L, Klein ML, Carnevale V
Proc. Natl. Acad. Sci. U.S.A. 113 (52) E8359-E8368 [2016-12-27; online 2016-12-12]
Affiliated researcher Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Pickering and Network Stabilization of Biocompatible Emulsions Using Chitosan-Modified Silica Nanoparticles.
Alison L, Rühs PA, Tervoort E, ..., Isa L, Studart AR
Langmuir 32 (50) 13446-13457 [2016-12-20; online 2016-12-09]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
BLISS: quantitative and versatile genome-wide profiling of DNA breaks in situ
Yan WX, Mirzazadeh R, Garnerone S, ..., Bienko M, Crosetto N
- - (-) - [2016-12-04; online 2016-12-04]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
The ace-1 Locus Is Amplified in All Resistant Anopheles gambiae Mosquitoes: Fitness Consequences of Homogeneous and Heterogeneous Duplications.
Assogba BS, Milesi P, Djogbénou LS, ..., Labbé P, Weill M
PLoS Biol. 14 (12) e2000618 [2016-12-00; online 2016-12-05]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Computational metabolic engineering strategies for growth-coupled biofuel production by Synechocystis.
Shabestary K, Hudson EP
Metabolic engineering communications 3 (-) 216-226 [2016-12-00; online 2016-07-20]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
ClpAP is an auxiliary protease for DnaA degradation in Caulobacter crescentus.
Liu J, Francis LI, Jonas K, Laub MT, Chien P
Mol. Microbiol. 102 (6) 1075-1085 [2016-12-00; online 2016-10-17]
Affiliated researcher Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Allochthonous carbon is a major regulator to bacterial growth and community composition in subarctic freshwaters
Roiha T, Peura S, Cusson M, Rautio M
Sci Rep 6 (1) - [2016-12-00; online 2016-09-30]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
A Kinase-Phosphatase Switch Transduces Environmental Information into a Bacterial Cell Cycle Circuit.
Heinrich K, Sobetzko P, Jonas K
PLoS Genet 12 (12) e1006522 [2016-12-00; online 2016-12-12]
Affiliated researcher Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Editorial: The Impact of Systems Medicine on Human Health and Disease.
Mardinoglu A, Nielsen J
Front. Physiol. 7 (-) 552 [2016-11-24; online 2016-11-24]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Exploring Spatio-temporal Dynamics of Cellular Automata for Pattern Recognition in Networks.
Miranda GHB, Machicao J, Bruno OM
Sci Rep 6 (-) 37329 [2016-11-22; online 2016-11-22]
Gisele Miranda SciLifeLab Fellow
PubMed DOI Crossref
Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis.
Ernst C, Pike J, Aitken SJ, ..., Kutter C, Odom DT
Elife 5 (-) - [2016-11-18; online 2016-11-18]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Adaptive Evolution of Phosphorus Metabolism in Prochlorococcus.
Casey JR, Mardinoglu A, Nielsen J, Karl DM
mSystems 1 (6) - [2016-11-15; online 2016-11-15]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Relating fitness to long-term environmental variations in natura.
Milesi P, Lenormand T, Lagneau C, Weill M, Labbé P
Mol. Ecol. 25 (21) 5483-5499 [2016-11-00; online 2016-10-14]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Rapid Restoration of Vascularity and Oxygenation in Mouse and Human Islets Transplanted to Omentum May Contribute to Their Superior Function Compared to Intraportally Transplanted Islets.
Espes D, Lau J, Quach M, ..., Christoffersson G, Carlsson PO
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 16 (11) 3246-3254 [2016-11-00; online 2016-07-22]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
MID-PREGNANCY CORTICOTROPIN-RELEASING HORMONE LEVELS IN ASSOCIATION WITH POSTPARTUM DEPRESSIVE SYMPTOMS.
Iliadis SI, Sylvén S, Hellgren C, ..., Sundström Poromaa I, Skalkidou A
Depress Anxiety 33 (11) 1023-1030 [2016-11-00; online 2016-05-27]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Corrigendum to "Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs" [Nucl Med Biol 43 (2016) 397-402].
Rydén A, Nyman G, Nalin L, ..., Eriksson O, Jensen-Waern M
Nucl. Med. Biol. 43 (11) 742 [2016-11-00; online 2016-09-07]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
ARAP2 promotes GLUT1-mediated basal glucose uptake through regulation of sphingolipid metabolism.
Chaudhari A, Håversen L, Mobini R, ..., Perkins R, Borén J
Biochim. Biophys. Acta 1861 (11) 1643-1651 [2016-11-00; online 2016-07-27]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Author response: Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis
Ernst C, Pike J, Aitken SJ, ..., Kutter C, Odom DT
- - (-) - [2016-10-31; online 2016-10-31]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Structure-Based Screening of Uncharted Chemical Space for Atypical Adenosine Receptor Agonists.
Rodríguez D, Chakraborty S, Warnick E, ..., Jacobson KA, Carlsson J
ACS chemical biology 11 (10) 2763-2772 [2016-10-21; online 2016-08-22]
Affiliated researcher Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Massive and parallel expression profiling using microarrayed single-cell sequencing.
Vickovic S, Ståhl PL, Salmén F, ..., Frisén J, Lundeberg J
Nat Commun 7 (1) 13182 [2016-10-14; online 2016-10-14]
Affiliated researcher Magda Bienko Sanja Vickovic SciLifeLab Fellow
DOI Crossref
Contrasting patterns of genome-level diversity across distinct co-occurring bacterial populations
Garcia SL, Stevens SLR, Crary B, ..., Malmstrom RR, McMahon KD
- - (-) - [2016-10-12; online 2016-10-12]
Sarahi Garcia SciLifeLab Fellow
DOI Crossref
The Chd1 chromatin remodeler shifts hexasomes unidirectionally
Levendosky RF, Sabantsev A, Deindl S, Bowman GD
- - (-) - [2016-10-09; online 2016-10-09]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Functional Metabolomics Describes the Yeast Biosynthetic Regulome
Mülleder M, Calvani E, Alam MT, ..., Zelezniak A, Ralser M
Cell 167 (2) 553-565.e12 [2016-10-00; online 2016-10-00]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
Associations between the FKBP5 haplotype, exposure to violence and anxiety in females.
Isaksson J, Comasco E, Åslund C, ..., Andershed H, Nilsson KW
Psychoneuroendocrinology 72 (-) 196-204 [2016-10-00; online 2016-07-15]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
A global genetic interaction network maps a wiring diagram of cellular function.
Costanzo M, VanderSluis B, Koch EN, ..., Andrews B, Boone C
Science (New York, N.Y.) 353 (6306) aaf1420-aaf1420 [2016-09-23; online 2016-10-07]
Affiliated researcher SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
IL-15 activates mTOR and primes stress-activated gene expression leading to prolonged antitumor capacity of NK cells.
Mao Y, van Hoef V, Zhang X, ..., Kiessling R, Lundqvist A
Blood 128 (11) 1475-1489 [2016-09-15; online 2016-07-27]
Affiliated researcher SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing.
Ferreira PG, Oti M, Barann M, ..., Guigó R, Sammeth M
Sci Rep 6 (1) 32406 [2016-09-12; online 2016-09-12]
Affiliated researcher Marc Friedländer SciLifeLab Fellow
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Berg OG, Mahmutovic A, Marklund E, Elf J
J. Phys. A: Math. Theor. 49 (36) 364002 [2016-09-09; online 2016-08-16]
Affiliated researcher Emil Marklund SciLifeLab Fellow
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Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade.
Eissler N, Mao Y, Brodin D, ..., Kiessling R, Kogner P
Oncoimmunology 5 (12) e1232222 [2016-09-09; online 2016-09-09]
SciLifeLab Fellow Yumeng Mao
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Transfer of developmental neurotoxin β-N-methylamino-l-alanine (BMAA) via milk to nursed offspring: Studies by mass spectrometry and image analysis.
Andersson M, Karlsson O, Banack SA, Brandt I
Toxicol. Lett. 258 (-) 108-114 [2016-09-06; online 2016-06-16]
Oskar Karlsson SciLifeLab Fellow
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Use of BODIPY-Cholesterol (TF-Chol) for Visualizing Lysosomal Cholesterol Accumulation.
Hölttä-Vuori M, Sezgin E, Eggeling C, Ikonen E
Traffic 17 (9) 1054-1057 [2016-09-00; online 2016-06-13]
Erdinc Sezgin SciLifeLab Fellow
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Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters.
Chen Y, Pai AA, Herudek J, ..., Jensen TH, Sandelin A
Nat. Genet. 48 (9) 984-994 [2016-09-00; online 2016-07-25]
Affiliated researcher SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Positron Emission Tomography to Assess the Outcome of Intraportal Islet Transplantation.
Eriksson O, Selvaraju R, Eich T, ..., Lundgren T, Korsgren O
Diabetes 65 (9) 2482-2489 [2016-09-00; online 2016-06-20]
Olof Eriksson SciLifeLab Fellow
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Pancreatic perfusion and subsequent response to glucose in healthy individuals and patients with type 1 diabetes.
Carlbom L, Espes D, Lubberink M, ..., Ahlström H, Carlsson PO
Diabetologia 59 (9) 1968-1972 [2016-09-00; online 2016-06-16]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Gender transition affects neural correlates of empathy: A resting state functional connectivity study with ultra high-field 7T MR imaging.
Spies M, Hahn A, Kranz GS, ..., Kasper S, Lanzenberger R
NeuroImage 138 (-) 257-265 [2016-09-00; online 2016-05-26]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Functional Relationship between a Dinoflagellate Host and Its Diatom Endosymbiont.
Hehenberger E, Burki F, Kolisko M, Keeling PJ
Mol. Biol. Evol. 33 (9) 2376-2390 [2016-09-00; online 2016-06-13]
Affiliated researcher Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
A Deeper Look into Type 1 Diabetes - Imaging Immune Responses during Onset of Disease.
Christoffersson G, von Herrath MG
Front Immunol 7 (-) 313 [2016-08-15; online 2016-08-15]
Gustaf Christoffersson SciLifeLab Fellow
DOI Crossref
Mixed cultures as model communities: hunting for ubiquitous microorganisms, their partners, and interactions
Garcia S
Aquat. Microb. Ecol. 77 (2) 79-85 [2016-08-12; online 2016-08-12]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
IFN-γ Hinders Recovery from Mucosal Inflammation during Antibiotic Therapy for Salmonella Gut Infection.
Dolowschiak T, Mueller AA, Pisan LJ, ..., Mueller C, Hardt WD
Cell Host Microbe 20 (2) 238-249 [2016-08-10; online 2016-07-21]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Photoswitchable Spiropyran Dyads for Biological Imaging.
Xiong Y, Rivera-Fuentes P, Sezgin E, ..., Eggeling C, Anderson HL
Org. Lett. 18 (15) 3666-3669 [2016-08-05; online 2016-07-26]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Targeting Suppressive Myeloid Cells Potentiates Checkpoint Inhibitors to Control Spontaneous Neuroblastoma.
Mao Y, Eissler N, Blanc KL, ..., Kogner P, Kiessling R
Clin. Cancer Res. 22 (15) 3849-3859 [2016-08-01; online 2016-03-08]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Skeletal response to diet with soya bean seeds used as primary source of protein in growing broiler chickens.
Olkowski B, Charuta A, Radzki R, Bieńko M, Toczko R
Journal of animal physiology and animal nutrition 100 (4) 731-737 [2016-08-00; online 2016-02-08]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Rapid Evolution of Genomic Imprinting in Two Species of the Brassicaceae.
Hatorangan MR, Laenen B, Steige KA, Slotte T, Köhler C
Plant Cell 28 (8) 1815-1827 [2016-08-00; online 2016-07-27]
Affiliated researcher SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Quantification of β-Cell Mass in Intramuscular Islet Grafts Using Radiolabeled Exendin-4.
Espes D, Selvaraju R, Velikyan I, ..., Carlsson PO, Eriksson O
Transplantation direct 2 (8) e93 [2016-08-00; online 2016-07-22]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Probing amyloid-β pathology in transgenic Alzheimer's disease (tgArcSwe) mice using MALDI imaging mass spectrometry.
Carlred L, Michno W, Kaya I, ..., Syvänen S, Hanrieder J
J. Neurochem. 138 (3) 469-478 [2016-08-00; online 2016-05-26]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Liver: Phenotypic and genetic variance: a systems approach to the liver.
Mardinoglu A, Uhlén M
Nat Rev Gastroenterol Hepatol 13 (8) 439-440 [2016-08-00; online 2016-06-22]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Computer-Aided Production of Scaffolded DNA Nanostructures from Flat Sheet Meshes.
Benson E, Mohammed A, Bosco A, ..., Orponen P, Högberg B
Angew. Chem. Int. Ed. Engl. 55 (31) 8869-8872 [2016-07-25; online 2016-06-15]
Erik Benson SciLifeLab Fellow
PubMed DOI Crossref
Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance.
Lee S, Zhang C, Kilicarslan M, ..., Boren J, Mardinoglu A
Cell Metab. 24 (1) 172-184 [2016-07-12; online 2016-06-23]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Directly linked hydroporphyrin dimers.
Xiong R, Arkhypchuk AI, Kovacs D, Orthaber A, Eszter Borbas K
Chem. Commun. (Camb.) 52 (58) 9056-9058 [2016-07-12; online 2016-02-10]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Dysregulated signaling hubs of liver lipid metabolism reveal hepatocellular carcinoma pathogenesis.
Lee S, Mardinoglu A, Zhang C, Lee D, Nielsen J
Nucleic Acids Res. 44 (12) 5529-5539 [2016-07-08; online 2016-05-23]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Visualization and analysis of gene expression in tissue sections by spatial transcriptomics.
Ståhl PL, Salmén F, Vickovic S, ..., Lundeberg J, Frisén J
Science (New York, N.Y.) 353 (6294) 78-82 [2016-07-01; online 2016-07-02]
Affiliated researcher Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Assembly scaffolding with PE-contaminated mate-pair libraries.
Sahlin K, Chikhi R, Arvestad L
Bioinformatics 32 (13) 1925-1932 [2016-07-01; online 2016-03-02]
Affiliated researcher Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Physical and verbal aggressive behavior and COMT genotype: Sensitivity to the environment.
Tuvblad C, Narusyte J, Comasco E, ..., Fanti KA, Nilsson KW
Am. J. Med. Genet. B Neuropsychiatr. Genet. 171 (5) 708-718 [2016-07-00; online 2016-02-17]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Morphological stability of microencapsulated vitamin formulations by AFM imaging
Mougin K, Bruntz A, Severin D, Teleki A
Food Structure 9 (-) 1-12 [2016-07-00; online 2016-07-00]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
Measurement‐based wireless network planning, monitoring, and reconfiguration solution for robust radio communications in indoor factories
Gong X, Trogh J, Braet Q, ..., Martens L, Joseph W
IET Science, Measurement & Technology 10 (4) 375-382 [2016-07-00; online 2016-07-00]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
In vivo imaging of beta cells with radiotracers: state of the art, prospects and recommendations for development and use.
Eriksson O, Laughlin M, Brom M, ..., Bonadonna R, Gotthardt M
Diabetologia 59 (7) 1340-1349 [2016-07-00; online 2016-04-19]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Corticolimbic anatomical characteristics predetermine risk for chronic pain.
Vachon-Presseau E, Tétreault P, Petre B, ..., Baliki MN, Apkarian AV
Brain 139 (Pt 7) 1958-1970 [2016-07-00; online 2016-05-05]
Affiliated researcher Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs.
Rydén A, Nyman G, Nalin L, ..., Eriksson O, Jensen-Waern M
Nucl. Med. Biol. 43 (7) 397-402 [2016-07-00; online 2016-04-16]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly.
Hunziker M, Barandun J, Petfalski E, ..., Tollervey D, Klinge S
Nat Commun 7 (-) 12090 [2016-06-29; online 2016-06-29]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy.
Steshenko O, Andrade DM, Honigmann A, ..., Simons M, Eggeling C
Biophys. J. 110 (11) 2441-2450 [2016-06-07; online 2016-06-09]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Early predictors of behavioural problems in pre-schoolers - a longitudinal study of constitutional and environmental main and interaction effects.
Agnafors S, Sydsjö G, Comasco E, ..., Oreland L, Svedin CG
BMC Pediatr 16 (-) 76 [2016-06-07; online 2016-06-07]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Genetic Basis for Red Coloration in Birds.
Lopes RJ, Johnson JD, Toomey MB, ..., Corbo JC, Carneiro M
Curr. Biol. 26 (11) 1427-1434 [2016-06-06; online 2016-05-19]
Mafalda Sousa Ferreira SciLifeLab Fellow
PubMed DOI Crossref
Feasibility of Multiple Examinations Using (68)Ga-Labelled Collagelin Analogues: Organ Distribution in Rat for Extrapolation to Human Organ and Whole-Body Radiation Dosimetry.
Velikyan I, Rosenström U, Bulenga TN, Eriksson O, Antoni G
Pharmaceuticals (Basel, Switzerland) 9 (2) - [2016-06-06; online 2016-06-06]
Olof Eriksson SciLifeLab Fellow
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Organization and Regulation of Mitochondrial Protein Synthesis.
Ott M, Amunts A, Brown A
Annu. Rev. Biochem. 85 (1) 77-101 [2016-06-02; online 2016-01-18]
Affiliated researcher Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
GPR44 is a pancreatic protein restricted to the human beta cell.
Hellström-Lindahl E, Danielsson A, Ponten F, ..., Johansson L, Eriksson O
Acta Diabetol 53 (3) 413-421 [2016-06-00; online 2015-10-14]
Affiliated researcher Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation.
Chlamydas S, Holz H, Samata M, ..., Steinmetz LM, Akhtar A
Nat. Struct. Mol. Biol. 23 (6) 580-589 [2016-06-00; online 2016-05-16]
Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection.
Müller AA, Dolowschiak T, Sellin ME, ..., LeibundGut-Landmann S, Hardt WD
PLoS Pathog 12 (6) e1005723 [2016-06-00; online 2016-06-24]
Mikael Sellin SciLifeLab Fellow
DOI Crossref
Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters
Chen Y, Pai AA, Herudek J, ..., Heick Jensen T, Sandelin A
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SciLifeLab Fellow
PubMed DOI Crossref
Mitochondrial Evolution: Going, Going, Gone.
Burki F
Curr. Biol. 26 (10) R410-R412 [2016-05-23; online 2016-05-25]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons.
García-Martínez J, Delgado-Ramos L, Ayala G, ..., Chávez S, Pérez-Ortín JE
Nucleic Acids Res. 44 (8) 3643-3658 [2016-05-05; online 2015-12-29]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Investigating the Combinatory Effects of Biological Networks on Gene Co-expression.
Zhang C, Lee S, Mardinoglu A, Hua Q
Front. Physiol. 7 (-) 160 [2016-05-02; online 2016-05-02]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Rpb1 foot mutations demonstrate a major role of Rpb4 in mRNA stability during stress situations in yeast.
Garrido-Godino AI, García-López MC, García-Martínez J, ..., Pérez-Ortín JE, Navarro F
Biochim. Biophys. Acta 1859 (5) 731-743 [2016-05-00; online 2016-03-18]
Affiliated researcher SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model.
Spiegelberg D, Mortensen AC, Selvaraju RK, ..., Stenerlöw B, Nestor M
Eur. J. Nucl. Med. Mol. Imaging 43 (5) 974-982 [2016-05-00; online 2015-12-01]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Gap Filling as Exact Path Length Problem.
Salmela L, Sahlin K, Mäkinen V, Tomescu AI
J. Comput. Biol. 23 (5) 347-361 [2016-05-00; online 2016-03-09]
Affiliated researcher Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States.
Rudolph KL, Schmitt BM, Villar D, ..., Kutter C, Odom DT
PLoS Genet 12 (5) e1006024 [2016-05-00; online 2016-05-11]
Affiliated researcher Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Systems biology analysis of hepatitis C virus infection reveals the role of copy number increases in regions of chromosome 1q in hepatocellular carcinoma metabolism.
Elsemman IE, Mardinoglu A, Shoaie S, Soliman TH, Nielsen J
Mol Biosyst 12 (5) 1496-1506 [2016-04-26; online 2016-04-05]
Adil Mardinoglu Affiliated researcher Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Cytosolic splice isoform of Hsp70 nucleotide exchange factor Fes1 is required for the degradation of misfolded proteins in yeast.
Gowda NK, Kaimal JM, Masser AE, ..., Friedländer MR, Andréasson C
Mol. Biol. Cell 27 (8) 1210-1219 [2016-04-15; online 2016-02-24]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Transcriptomics resources of human tissues and organs.
Uhlén M, Hallström BM, Lindskog C, ..., Pontén F, Nielsen J
Mol Syst Biol 12 (4) 862 [2016-04-04; online 2016-04-04]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Sleep duration, depression, and oxytocinergic genotype influence prepulse inhibition of the startle reflex in postpartum women.
Comasco E, Gulinello M, Hellgren C, ..., Sylven S, Sundström-Poromaa I
Eur Neuropsychopharmacol 26 (4) 767-776 [2016-04-00; online 2016-01-22]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Genomic legacies of the progenitors and the evolutionary consequences of allopolyploidy.
Steige KA, Slotte T
Current Opinion in Plant Biology 30 (-) 88-93 [2016-04-00; online 2016-03-01]
Affiliated researcher SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Evolutionary Origins of Rhizarian Parasites.
Sierra R, Cañas-Duarte SJ, Burki F, ..., Arzul I, Pawlowski J
Mol. Biol. Evol. 33 (4) 980-983 [2016-04-00; online 2015-12-16]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Multiple Gene Repression in Cyanobacteria Using CRISPRi.
Yao L, Cengic I, Anfelt J, Hudson EP
ACS Synth. Biol. 5 (3) 207-212 [2016-03-18; online 2015-12-28]
Affiliated researcher Paul Hudson SciLifeLab Fellow
DOI Crossref
The role of transposable elements for gene expression in Capsella hybrids and allopolyploids
Steige KA, Reimegård J, Rebernig CA, ..., Scofield DG, Slotte T
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SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Landscape and Dynamics of Transcription Initiation in the Malaria Parasite Plasmodium falciparum.
Adjalley SH, Chabbert CD, Klaus B, Pelechano V, Steinmetz LM
Cell Reports 14 (10) 2463-2475 [2016-03-15; online 2016-03-03]
Affiliated researcher SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
FoCuS-point: software for STED fluorescence correlation and time-gated single photon counting.
Waithe D, Clausen MP, Sezgin E, Eggeling C
Bioinformatics 32 (6) 958-960 [2016-03-15; online 2015-11-20]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Glycation Reactivity of a Quorum-Sensing Signaling Molecule.
Tsuchikama K, Gooyit M, Harris TL, ..., Kaufmann GF, Janda KD
Angew. Chem. Int. Ed. Engl. 55 (12) 4002-4006 [2016-03-14; online 2016-02-17]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Specific small-RNA signatures in the amygdala at premotor and motor stages of Parkinson's disease revealed by deep sequencing analysis.
Pantano L, Friedländer MR, Escaramís G, ..., Estivill X, Martí E
Bioinformatics 32 (5) 673-681 [2016-03-01; online 2015-11-02]
Marc Friedländer SciLifeLab Fellow
DOI Crossref
Shape optimization of a cyclone separator using multi-objective surrogate-based optimization
Singh P, Couckuyt I, Elsayed K, Deschrijver D, Dhaene T
Applied Mathematical Modelling 40 (5-6) 4248-4259 [2016-03-00; online 2016-03-00]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Arabidopsis acyl-acyl carrier protein synthetase AAE15 with medium chain fatty acid specificity is functional in cyanobacteria.
Kaczmarzyk D, Hudson EP, Fulda M
AMB Expr 6 (1) 7 [2016-03-00; online 2016-01-21]
Affiliated researcher Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Molecularly designed lipid microdomains for solid dispersions using a polymer/inorganic carrier matrix produced by hot-melt extrusion.
Adler C, Schönenberger M, Teleki A, Kuentz M
Int J Pharm 499 (1-2) 90-100 [2016-02-29; online 2015-12-22]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Stepwise nucleosome translocation by RSC remodeling complexes.
Harada BT, Hwang WL, Deindl S, ..., Bartholomew B, Zhuang X
Elife 5 (-) - [2016-02-19; online 2016-02-19]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
The metabolic background is a global player in Saccharomyces gene expression epistasis
Alam MT, Zelezniak A, Mülleder M, ..., Lilley KS, Ralser M
Nat. Microbiol 1 (3) 15030 [2016-02-01; online 2016-02-01]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
Next-generation sequencing of the basal cell carcinoma miRNome and a description of novel microRNA candidates under neoadjuvant vismodegib therapy: an integrative molecular and surgical case study.
Sand M, Bechara FG, Gambichler T, ..., Schnabel R, Hessam S
Ann. Oncol. 27 (2) 332-338 [2016-02-00; online 2015-11-16]
Affiliated researcher Marc Friedländer SciLifeLab Fellow
DOI Crossref
If Gel and Mass Spec Don't Help, Use cryo-EM to Characterise your Specimen
Amunts A
Biophysical Journal 110 (3) 10a [2016-02-00; online 2016-02-00]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide quantification of 5'-phosphorylated mRNA degradation intermediates for analysis of ribosome dynamics.
Pelechano V, Wei W, Steinmetz LM
Nat Protoc 11 (2) 359-376 [2016-02-00; online 2016-01-28]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Genetic code expansion in stable cell lines enables encoded chromatin modification.
Elsässer SJ, Ernst RJ, Walker OS, Chin JW
Nat. Methods 13 (2) 158-164 [2016-02-00; online 2016-01-04]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma.
Haylock AK, Spiegelberg D, Mortensen AC, ..., Tolmachev V, Nestor MV
Int. J. Oncol. 48 (2) 461-470 [2016-02-00; online 2015-12-14]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
A comparative study on fluorescent cholesterol analogs as versatile cellular reporters.
Sezgin E, Can FB, Schneider F, ..., Platt F, Eggeling C
J. Lipid Res. 57 (2) 299-309 [2016-02-00; online 2015-12-23]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Untangling the early diversification of eukaryotes: a phylogenomic study of the evolutionary origins of Centrohelida, Haptophyta and Cryptista.
Burki F, Kaplan M, Tikhonenkov DV, ..., Mylnikov AP, Keeling PJ
Proc. Biol. Sci. 283 (1823) 20152802 [2016-01-27; online 2016-01-27]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Recent advances in understanding Type 1 Diabetes.
Christoffersson G, Rodriguez-Calvo T, von Herrath M
F1000Res 5 (-) - [2016-01-27; online 2016-01-27]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes.
Walker OS, Elsässer SJ, Mahesh M, ..., Balasubramanian S, Chin JW
Journal of the American Chemical Society 138 (3) 718-721 [2016-01-27; online 2016-01-12]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Personalized Cardiovascular Disease Prediction and Treatment-A Review of Existing Strategies and Novel Systems Medicine Tools.
Björnson E, Borén J, Mardinoglu A
Front. Physiol. 7 (-) 2 [2016-01-26; online 2016-01-26]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
HPA Axis Gene Expression and DNA Methylation Profiles in Rats Exposed to Early Life Stress, Adult Voluntary Ethanol Drinking and Single Housing.
Todkar A, Granholm L, Aljumah M, ..., Comasco E, Nylander I
Front Mol Neurosci 8 (-) 90 [2016-01-26; online 2016-01-26]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Structural variation detection with read pair information — An improved null-hypothesis reduces bias
Sahlin K, Frånberg M, Arvestad L
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Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin.
Elokely K, Velisetty P, Delemotte L, ..., Rohacs T, Carnevale V
Proc. Natl. Acad. Sci. U.S.A. 113 (2) E137-E145 [2016-01-12; online 2015-12-30]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Confounding Effects of Metformin on the Human Gut Microbiome in Type 2 Diabetes.
Mardinoglu A, Boren J, Smith U
Cell Metab. 23 (1) 10-12 [2016-01-12; online 2016-01-16]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Structural Variation Detection with Read Pair Information—An Improved Null-Hypothesis Reduces Bias
Sahlin K, Frånberg M, Arvestad L
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Kristoffer Sahlin SciLifeLab Fellow
DOI Crossref
Highly scalable production of uniformly-coated superparamagnetic nanoparticles for triggered drug release from alginate hydrogels
Teleki A, Haufe FL, Hirt AM, Pratsinis SE, Sotiriou GA
RSC Adv. 6 (26) 21503-21510 [2016-00-00; online 2016-00-00]
Alexandra Teleki SciLifeLab Fellow

Year 2015

PubMed DOI Crossref
Litomosoides sigmodontis: a jird urine metabolome study.
Globisch D, Specht S, Pfarr KM, ..., Hoerauf A, Janda KD
Bioorg. Med. Chem. Lett. 25 (24) 5804-5807 [2015-12-15; online 2015-10-23]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Effect of voluntary alcohol consumption on Maoa expression in the mesocorticolimbic brain of adult male rats previously exposed to prolonged maternal separation.
Bendre M, Comasco E, Nylander I, Nilsson KW
Transl Psychiatry 5 (12) e690 [2015-12-08; online 2015-12-08]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
The Cannabinoid Receptor-1 Is an Imaging Biomarker of Brown Adipose Tissue.
Eriksson O, Mikkola K, Espes D, ..., Solin O, Nuutila P
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 56 (12) 1937-1941 [2015-12-00; online 2015-09-10]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Psychiatric symptoms in adolescents: FKBP5 genotype--early life adversity interaction effects.
Comasco E, Gustafsson PA, Sydsjö G, ..., Aho N, Svedin CG
Eur Child Adolesc Psychiatry 24 (12) 1473-1483 [2015-12-00; online 2015-09-30]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides
Gosselin-Badaroudine P, Moreau A, Delemotte L, ..., Klein ML, Chahine M
Sci Rep 5 (1) - [2015-12-00; online 2015-07-23]
Lucie Delemotte SciLifeLab Fellow
DOI Crossref
The 2015 super-resolution microscopy roadmap
Hell SW, Sahl SJ, Bates M, ..., Diaspro A, Cordes T
J. Phys. D: Appl. Phys. 48 (44) 443001 [2015-11-11; online 2015-10-15]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Flow-through cross-polarized imaging as a new tool to overcome the analytical sensitivity challenges of a low-dose crystalline compound in a lipid matrix.
Adler C, Schönenberger M, Teleki A, Leuenberger B, Kuentz M
J Pharm Biomed Anal 115 (-) 20-30 [2015-11-10; online 2015-06-24]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Stage-specific assembly events of the 6-MDa small-subunit processome initiate eukaryotic ribosome biogenesis.
Chaker-Margot M, Hunziker M, Barandun J, Dill BD, Klinge S
Nat. Struct. Mol. Biol. 22 (11) 920-923 [2015-11-00; online 2015-10-19]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Functional characterization of zebrafish cytochrome P450 1 family proteins expressed in yeast.
Stegeman JJ, Behrendt L, Woodin BR, ..., Goldstone JV, Urban P
Biochim. Biophys. Acta 1850 (11) 2340-2352 [2015-11-00; online 2015-07-29]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans.
Massena S, Christoffersson G, Vågesjö E, ..., Kreuger J, Phillipson M
Blood 126 (17) 2016-2026 [2015-10-22; online 2015-08-18]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Biotin-Genomic Run-On (Bio-GRO): A High-Resolution Method for the Analysis of Nascent Transcription in Yeast.
Jordán-Pla A, Miguel A, Serna E, Pelechano V, Pérez-Ortín JE
Methods in molecular biology (Clifton, N.J.) 1361 (-) 125-139 [2015-10-21; online 2015-10-21]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Genome-Wide Identification of Alternative Polyadenylation Events Using 3'T-Fill.
Wilkening S, Pelechano V, Steinmetz LM
Methods in molecular biology (Clifton, N.J.) 1358 (-) 295-302 [2015-10-16; online 2015-10-16]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
A straightforward approach for gated STED-FCS to investigate lipid membrane dynamics.
Clausen MP, Sezgin E, Bernardino de la Serna J, ..., Lagerholm BC, Eggeling C
Methods 88 (-) 67-75 [2015-10-15; online 2015-06-27]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
An ace-1 gene duplication resorbs the fitness cost associated with resistance in Anopheles gambiae, the main malaria mosquito.
Assogba BS, Djogbénou LS, Milesi P, ..., Labbé P, Weill M
Sci Rep 5 (-) 14529 [2015-10-05; online 2015-10-05]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
The gut microbiota modulates host amino acid and glutathione metabolism in mice
Mardinoglu A, Shoaie S, Bergentall M, ..., Bäckhed F, Nielsen J
Mol Syst Biol 11 (10) 834 [2015-10-00; online 2015-10-16]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Systematic screening of imaging biomarkers for the Islets of Langerhans, among clinically available positron emission tomography tracers.
Karlsson F, Antonodimitrakis PC, Eriksson O
Nucl. Med. Biol. 42 (10) 762-769 [2015-10-00; online 2015-06-10]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Supraphysiological hormonal status, anxiety disorders, and COMT Val/Val genotype are associated with reduced sensorimotor gating in women.
Comasco E, Hellgren C, Olivier J, Skalkidou A, Sundström Poromaa I
Psychoneuroendocrinology 60 (-) 217-223 [2015-10-00; online 2015-07-02]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Neuroimaging the Menstrual Cycle and Premenstrual Dysphoric Disorder.
Comasco E, Sundström-Poromaa I
Curr Psychiatry Rep 17 (10) 77 [2015-10-00; online 2015-08-15]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Canine CNGA3 Gene Mutations Provide Novel Insights into Human Achromatopsia-Associated Channelopathies and Treatment
Tanaka N, Dutrow EV, Miyadera K, ..., Tanaka JC, Guziewicz KE
PLoS ONE 10 (9) e0138943 [2015-09-25; online 2015-09-25]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
STED-FLCS: An Advanced Tool to Reveal Spatiotemporal Heterogeneity of Molecular Membrane Dynamics.
Vicidomini G, Ta H, Honigmann A, ..., Hell SW, Eggeling C
Nano Lett. 15 (9) 5912-5918 [2015-09-09; online 2015-08-07]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
[11C]Carfentanil Binds Preferentially to μ-Opioid Receptor Subtype 1 Compared to Subtype 2
Eriksson O, Antoni G
Mol Imaging 14 (9) 7290.2015.00019 [2015-09-00; online 2015-09-00]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Computer-aided diagnosis system based on fuzzy logic for breast cancer categorization.
Miranda GH, Felipe JC
Comput Biol Med 64 (-) 334-346 [2015-09-00; online 2014-10-14]
Gisele Miranda SciLifeLab Fellow
PubMed DOI Crossref
Chlorophyll f-driven photosynthesis in a cavernous cyanobacterium.
Behrendt L, Brejnrod A, Schliep M, ..., Larkum AW, Kühl M
ISME J 9 (9) 2108-2111 [2015-09-00; online 2015-02-10]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Prenatal and Postpartum Evening Salivary Cortisol Levels in Association with Peripartum Depressive Symptoms.
Iliadis SI, Comasco E, Sylvén S, ..., Sundström Poromaa I, Skalkidou A
PLoS ONE 10 (8) e0135471 [2015-08-31; online 2015-08-31]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Factors mediating plastid dependency and the origins of parasitism in apicomplexans and their close relatives
Janouškovec J, Tikhonenkov DV, Burki F, ..., Mylnikov AP, Keeling PJ
Proceedings of the National Academy of Sciences 112 (33) 10200-10207 [2015-08-18; online 2015-02-25]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome.
Shoaie S, Ghaffari P, Kovatcheva-Datchary P, ..., Bäckhed F, Nielsen J
Cell Metab. 22 (2) 320-331 [2015-08-04; online 2015-08-06]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Treatment with serotonin reuptake inhibitors during pregnancy is associated with elevated corticotropin-releasing hormone levels.
Hannerfors AK, Hellgren C, Schijven D, ..., Olivier JD, Sundström-Poromaa I
Psychoneuroendocrinology 58 (-) 104-113 [2015-08-00; online 2015-04-21]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory
Cournia Z, Allen TW, Andricioaei I, ..., Smith JC, Bondar AN
J Membrane Biol 248 (4) 611-640 [2015-08-00; online 2015-06-11]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Inflammasomes of the intestinal epithelium
Sellin ME, Maslowski KM, Maloy KJ, Hardt WD
Trends in Immunology 36 (8) 442-450 [2015-08-00; online 2015-08-00]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Global SUMOylation on active chromatin is an acute heat stress response restricting transcription.
Niskanen EA, Malinen M, Sutinen P, ..., Sistonen L, Palvimo JJ
Genome Biol. 16 (1) 153 [2015-07-28; online 2015-07-28]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
DNA rendering of polyhedral meshes at the nanoscale.
Benson E, Mohammed A, Gardell J, ..., Orponen P, Högberg B
Nature 523 (7561) 441-444 [2015-07-23; online 2015-07-24]
Erik Benson SciLifeLab Fellow
PubMed DOI Crossref
Mitochondrial ribosome assembly in health and disease
De Silva D, Tu YT, Amunts A, Fontanesi F, Barrientos A
Cell Cycle 14 (14) 2226-2250 [2015-07-18; online 2015-06-00]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Logical transformation of genome-scale metabolic models for gene level applications and analysis.
Zhang C, Ji B, Mardinoglu A, Nielsen J, Hua Q
Bioinformatics 31 (14) 2324-2331 [2015-07-15; online 2015-03-02]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Nutritional Control of DNA Replication Initiation through the Proteolysis and Regulated Translation of DnaA
Leslie DJ, Heinen C, Schramm FD, ..., Laub MT, Jonas K
PLoS Genet 11 (7) e1005342 [2015-07-02; online 2015-07-02]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Critical Role of Histone Turnover in Neuronal Transcription and Plasticity.
Maze I, Wenderski W, Noh KM, ..., Molina H, Allis CD
Neuron 87 (1) 77-94 [2015-07-01; online 2015-07-04]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
The Nuclear PolyA-Binding Protein Nab2p Is Essential for mRNA Production
Schmid M, Olszewski P, Pelechano V, ..., Steinmetz LM, Jensen TH
Cell Reports 12 (1) 128-139 [2015-07-00; online 2015-07-00]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Comparative sequence analysis suggests a conserved gating mechanism for TRP channels
Palovcak E, Delemotte L, Klein ML, Carnevale V
J Gen Physiol 146 (1) 37-50 [2015-07-00; online 2015-06-15]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Αlpha 2a-Adrenoceptor Gene Expression and Early Life Stress-Mediated Propensity to Alcohol Drinking in Outbred Rats.
Comasco E, Todkar A, Granholm L, Nilsson KW, Nylander I
Int J Environ Res Public Health 12 (7) 7154-7171 [2015-06-25; online 2015-06-25]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Two steps forward, one step back: successes and failures in structure-based discovery of GPCR ligands.
Carlsson J
Springerplus 4 (Suppl 1) L5 [2015-06-12; online 2015-06-12]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Single-cell polyadenylation site mapping reveals 3' isoform choice variability.
Velten L, Anders S, Pekowska A, ..., Pelechano V, Steinmetz LM
Mol Syst Biol 11 (6) 812 [2015-06-03; online 2015-06-03]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Widespread Co-translational RNA Decay Reveals Ribosome Dynamics
Pelechano V, Wei W, Steinmetz LM
Cell 161 (6) 1400-1412 [2015-06-00; online 2015-06-00]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Non-reciprocal Interspecies Hybridization Barriers in the Capsella Genus Are Established in the Endosperm.
Rebernig CA, Lafon-Placette C, Hatorangan MR, Slotte T, Köhler C
PLoS Genet 11 (6) e1005295 [2015-06-00; online 2015-06-18]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Dendritic cell regulation of NK-cell responses involves lymphotoxin-α, IL-12, and TGF-β.
Sarhan D, Palma M, Mao Y, ..., Österborg A, Lundqvist A
Eur. J. Immunol. 45 (6) 1783-1793 [2015-06-00; online 2015-04-17]
SciLifeLab Fellow Yumeng Mao
DOI Crossref
A chemoenzymatic approach toward the preparation of site-specific antibody–drug conjugates
Cai X, Janda KD
Tetrahedron Letters 56 (23) 3172-3175 [2015-06-00; online 2015-06-00]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Purification of functionalized DNA origami nanostructures.
Shaw A, Benson E, Högberg B
ACS Nano 9 (5) 4968-4975 [2015-05-26; online 2015-05-12]
Erik Benson SciLifeLab Fellow
PubMed DOI Crossref
Metabolic dependencies drive species co-occurrence in diverse microbial communities
Zelezniak A, Andrejev S, Ponomarova O, ..., Bork P, Patil KR
Proceedings of the National Academy of Sciences 112 (20) 6449-6454 [2015-05-19; online 2015-05-04]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
Spectral imaging to measure heterogeneity in membrane lipid packing.
Sezgin E, Waithe D, Bernardino de la Serna J, Eggeling C
Chemphyschem 16 (7) 1387-1394 [2015-05-18; online 2015-03-05]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Proteome- and transcriptome-driven reconstruction of the human myocyte metabolic network and its use for identification of markers for diabetes.
Väremo L, Scheele C, Broholm C, ..., Pedersen BK, Nielsen J
Cell Reports 11 (6) 921-933 [2015-05-12; online 2015-04-30]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Human genomics. Effect of predicted protein-truncating genetic variants on the human transcriptome.
Rivas MA, Pirinen M, Conrad DF, ..., Lappalainen T, MacArthur DG
Science (New York, N.Y.) 348 (6235) 666-669 [2015-05-08; online 2015-05-09]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Membrane nanoclusters-tails of the unexpected.
Sezgin E, Davis SJ, Eggeling C
Cell 161 (3) 433-434 [2015-04-23; online 2015-04-25]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Adaptive lipid packing and bioactivity in membrane domains.
Sezgin E, Gutmann T, Buhl T, ..., Levental I, Schwille P
PLoS ONE 10 (4) e0123930 [2015-04-23; online 2015-04-23]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells.
Ratz M, Testa I, Hell SW, Jakobs S
Sci Rep 5 (1) 9592 [2015-04-20; online 2015-04-20]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
The structure of the human mitochondrial ribosome
Amunts A, Brown A, Toots J, Scheres SHW, Ramakrishnan V
Science 348 (6230) 95-98 [2015-04-03; online 2015-04-02]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Behavioral cost & overdominance in Anopheles gambiae.
Diop MM, Moiroux N, Chandre F, ..., Labbé P, Pennetier C
PLoS ONE 10 (4) e0121755 [2015-04-01; online 2015-04-01]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Synthesis and biological evaluation of [¹¹C]AZ12504948; a novel tracer for imaging of glucokinase in pancreas and liver.
Jahan M, Johnström P, Nag S, ..., Halldin C, Eriksson O
Nucl. Med. Biol. 42 (4) 387-394 [2015-04-00; online 2014-12-06]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains.
Beck-García K, Beck-García E, Bohler S, ..., Alarcón B, Schamel WW
Biochim. Biophys. Acta 1853 (4) 802-809 [2015-04-00; online 2014-12-20]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Matrix metalloproteinase-9 is essential for physiological Beta cell function and islet vascularization in adult mice.
Christoffersson G, Waldén T, Sandberg M, ..., Carlsson PO, Phillipson M
Am. J. Pathol. 185 (4) 1094-1103 [2015-04-00; online 2015-02-07]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Integrated genome and transcriptome sequencing of the same cell.
Dey SS, Kester L, Spanjaard B, Bienko M, van Oudenaarden A
Nat. Biotechnol. 33 (3) 285-289 [2015-03-00; online 2015-01-19]
Magda Bienko SciLifeLab Fellow
PubMed
Dosimetry of [(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4 in rodents, pigs, non-human primates and human - repeated scanning in human is possible.
Selvaraju RK, Bulenga TN, Espes D, ..., Velikyan I, Eriksson O
American journal of nuclear medicine and molecular imaging 5 (3) 259-269 [2015-02-15; online 2015-02-15]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Synthesis and characterisation of lanthanide-hydroporphyrin dyads.
Xiong R, Andres J, Scheffler K, Borbas KE
Dalton Trans 44 (6) 2541-2553 [2015-02-14; online 2014-10-24]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Flagellin as carrier and adjuvant in cocaine vaccine development.
Lockner JW, Eubanks LM, Choi JL, ..., Wilson IA, Janda KD
Mol. Pharm. 12 (2) 653-662 [2015-02-02; online 2015-01-07]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy
Moreau A, Gosselin-Badaroudine P, Delemotte L, Klein ML, Chahine M
J Gen Physiol 145 (2) 93-106 [2015-02-00; online 2015-01-26]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics
Amunts A, Fiedorczuk K, Truong TT, ..., Greenberg EP, Ramakrishnan V
Journal of Molecular Biology 427 (4) 753-755 [2015-02-00; online 2015-02-00]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle
Jordán-Pla A, Gupta I, de Miguel-Jiménez L, ..., Pelechano V, Pérez-Ortín JE
Nucleic Acids Res. 43 (2) 787-802 [2015-01-30; online 2014-12-29]
SciLifeLab Fellow Vicente Pelechano
PubMed
Dosimetry of [(177)Lu]-DO3A-VS-Cys(40)-Exendin-4 - impact on the feasibility of insulinoma internal radiotherapy.
Velikyan I, Bulenga TN, Selvaraju R, ..., Rosenström U, Eriksson O
American journal of nuclear medicine and molecular imaging 5 (2) 109-126 [2015-01-15; online 2015-01-15]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Dual channel RESOLFT nanoscopy by using fluorescent state kinetics.
Testa I, D'Este E, Urban NT, Balzarotti F, Hell SW
Nano Lett. 15 (1) 103-106 [2015-01-14; online 2014-12-02]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
A high-throughput ChIP-Seq for large-scale chromatin studies.
Chabbert CD, Adjalley SH, Klaus B, ..., Pelechano V, Steinmetz LM
Mol Syst Biol 11 (1) 777 [2015-01-12; online 2015-01-12]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Free-energy landscape of ion-channel voltage-sensor–domain activation
Delemotte L, Kasimova MA, Klein ML, Tarek M, Carnevale V
Proceedings of the National Academy of Sciences 112 (1) 124-129 [2015-01-06; online 2014-12-22]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Modulation of Bacterial Proliferation as a Survival Strategy
Heinrich K, Leslie DJ, Jonas K
- - (-) 127-171 [2015-00-00; online 2015-00-00]
Kristina Jonas SciLifeLab Fellow

Year 2014

PubMed DOI Crossref
Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during Salmonella Typhimurium Colitis
Maier L, Diard M, Sellin ME, ..., Regoes RR, Hardt WD
PLoS Pathog 10 (12) e1004557 [2014-12-18; online 2014-12-18]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Genotypes do not confer risk for delinquency but rather alter susceptibility to positive and negative environmental factors: gene-environmentinteractions of BDNF Val66Met, 5-HTTLPR, and MAOA-uVNTR [corrected].
Nilsson KW, Comasco E, Hodgins S, Oreland L, Åslund C
Int J Neuropsychopharmacol 18 (5) - [2014-12-10; online 2014-12-10]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Functional and molecular neuroimaging of menopause and hormone replacement therapy.
Comasco E, Frokjaer VG, Sundström-Poromaa I
Front Neurosci 8 (-) 388 [2014-12-08; online 2014-12-08]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Phenotypic effects of concomitant insensitive acetylcholinesterase (ace-1(R)) and knockdown resistance (kdr(R)) in Anopheles gambiae: a hindrance for insecticide resistance management for malaria vector control.
Assogba BS, Djogbénou LS, Saizonou J, ..., Weill M, Makoutodé M
Parasit Vectors 7 (-) 548 [2014-12-03; online 2014-12-03]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Toxicogenomics directory of chemically exposed human hepatocytes
Grinberg M, Stöber RM, Edlund K, ..., Rahnenführer J, Hengstler JG
Arch Toxicol 88 (12) 2261-2287 [2014-12-00; online 2014-11-16]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
The Salmonella Typhimurium effector protein SopE transiently localizes to the early SCV and contributes to intracellular replication
Vonaesch P, Sellin ME, Cardini S, ..., Barthel M, Hardt WD
Cell Microbiol 16 (12) 1723-1735 [2014-12-00; online 2014-08-26]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Strategy to develop a MAO-A-resistant 5-hydroxy-L-[β-(11)C]tryptophan isotopologue based on deuterium kinetic isotope effects.
Eriksson J, Åberg O, Selvaraju RK, ..., Johansson L, Eriksson O
EJNMMI Res 4 (1) 62 [2014-12-00; online 2014-11-30]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Emotional and cognitive functional imaging of estrogen and progesterone effects in the female human brain: a systematic review.
Toffoletto S, Lanzenberger R, Gingnell M, Sundström-Poromaa I, Comasco E
Psychoneuroendocrinology 50 (-) 28-52 [2014-12-00; online 2014-08-13]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Classification aided domain reduction for high dimensional optimization
Singh P, Ferranti F, Deschrijver D, Couckuyt I, Dhaene T
- - (-) - [2014-12-00; online 2014-12-00]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Scanning STED-FCS reveals spatiotemporal heterogeneity of lipid interaction in the plasma membrane of living cells.
Honigmann A, Mueller V, Ta H, ..., Hell SW, Eggeling C
Nat Commun 5 (-) 5412 [2014-11-20; online 2014-11-20]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Mild Microwave-Assisted Synthesis of Dipyrromethanes and Their Analogues
Borbas K, Xiong R
Synlett 26 (04) 484-488 [2014-11-18; online 2014-11-18]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Single-cell transcriptomics for microbial eukaryotes.
Kolisko M, Boscaro V, Burki F, Lynn DH, Keeling PJ
Curr. Biol. 24 (22) R1081-R1082 [2014-11-17; online 2014-11-17]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Structure of the large ribosomal subunit from human mitochondria
Brown A, Amunts A, Bai Xc, ..., Scheres SHW, Ramakrishnan V
Science 346 (6210) 718-722 [2014-11-07; online 2014-10-02]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1
Schmied WH, Elsässer SJ, Uttamapinant C, Chin JW
J. Am. Chem. Soc. 136 (44) 15577-15583 [2014-11-05; online 2014-10-28]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Gallium-68-labeled affibody molecule for PET imaging of PDGFRβ expression in vivo.
Strand J, Varasteh Z, Eriksson O, ..., Orlova A, Tolmachev V
Mol. Pharm. 11 (11) 3957-3964 [2014-11-03; online 2014-07-23]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA–tRNA interface
Schmitt BM, Rudolph KLM, Karagianni P, ..., Marioni JC, Kutter C
Genome Res. 24 (11) 1797-1807 [2014-11-00; online 2014-08-13]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Haplotype-tag single nucleotide polymorphism analysis of the vesicular glutamate transporter (VGLUT) genes in severely alcoholic women.
Comasco E, Hallman J, Wallén-Mackenzie A
Psychiatry Res 219 (2) 403-405 [2014-10-30; online 2014-06-06]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways
Ballester B, Medina-Rivera A, Schmidt D, ..., Flicek P, Wilson MD
Elife 3 (-) - [2014-10-03; online 2014-10-03]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Synthesis and preclinical evaluation of 68Ga-labeled collagelin analogs for imaging and quantification of fibrosis.
Velikyan I, Rosenström U, Estrada S, ..., Eriksson O, Antoni G
Nucl. Med. Biol. 41 (9) 728-736 [2014-10-00; online 2014-06-09]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Specific targeting of human caspases using designed ankyrin repeat proteins.
Flütsch A, Schroeder T, Barandun J, ..., Bühlmann M, Grütter MG
Biol. Chem. 395 (10) 1243-1252 [2014-10-00; online 2014-08-26]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Positron emission tomography ligand [11C]5-hydroxy-tryptophan can be used as a surrogate marker for the human endocrine pancreas.
Eriksson O, Espes D, Selvaraju RK, ..., Carlsson PO, Korsgren O
Diabetes 63 (10) 3428-3437 [2014-10-00; online 2014-05-21]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Acute sleep deprivation in healthy young men: impact on population diversity and function of circulating neutrophils.
Christoffersson G, Vågesjö E, Pettersson US, ..., Benedict C, Phillipson M
Brain Behav. Immun. 41 (-) 162-172 [2014-10-00; online 2014-05-28]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Cell cycle: once out, never in again.
Jonas K
Curr. Biol. 24 (18) R841-R843 [2014-09-22; online 2014-09-24]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders
Blanco S, Dietmann S, Flores JV, ..., Odom DT, Frye M
The EMBO Journal 33 (18) 2020-2039 [2014-09-17; online 2014-07-25]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Antibiotic treatment selects for cooperative virulence of Salmonella typhimurium.
Diard M, Sellin ME, Dolowschiak T, ..., Ackermann M, Hardt WD
Curr. Biol. 24 (17) 2000-2005 [2014-09-08; online 2014-08-14]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Preferential activation by galanin 1–15 fragment of the GalR1 protomer of a GalR1–GalR2 heteroreceptor complex
Borroto-Escuela DO, Narvaez M, Di Palma M, ..., Díaz-Cabiale Z, Fuxe K
Biochemical and Biophysical Research Communications 452 (3) 347-353 [2014-09-00; online 2014-09-00]
Jens Carlsson SciLifeLab Fellow
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Positron emission tomography imaging of the glucagon-like peptide-1 receptor in healthy and streptozotocin-induced diabetic pigs.
Nalin L, Selvaraju RK, Velikyan I, ..., Eriksson O, Jensen-Waern M
Eur. J. Nucl. Med. Mol. Imaging 41 (9) 1800-1810 [2014-09-00; online 2014-03-19]
Olof Eriksson SciLifeLab Fellow
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Evidence for the Retention of Two Evolutionary Distinct Plastids in Dinoflagellates with Diatom Endosymbionts
Hehenberger E, Imanian B, Burki F, Keeling PJ
Genome Biol Evol 6 (9) 2321-2334 [2014-09-00; online 2014-08-28]
Fabien Burki SciLifeLab Fellow
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Emotional fronto-cingulate cortex activation and brain derived neurotrophic factor polymorphism in premenstrual dysphoric disorder.
Comasco E, Hahn A, Ganger S, ..., Lanzenberger R, Sundström-Poromaa I
Hum Brain Mapp 35 (9) 4450-4458 [2014-09-00; online 2014-02-25]
Erika Comasco SciLifeLab Fellow
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Tandem RNA chimeras contribute to transcriptome diversity in human population and are associated with intronic genetic variants.
Greger L, Su J, Rung J, ..., Dermitzakis ET, Brazma A
PLoS ONE 9 (8) e104567 [2014-08-18; online 2014-08-18]
Affiliated researcher Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Characterisation of novel microRNAs in the Black flying fox (Pteropus alecto) by deep sequencing.
Cowled C, Stewart CR, Likic VA, ..., Bean AG, Wang LF
BMC Genomics 15 (1) 682 [2014-08-15; online 2014-08-15]
Marc Friedländer SciLifeLab Fellow
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Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA.
Hwang WL, Deindl S, Harada BT, Zhuang X
Nature 512 (7513) 213-217 [2014-08-14; online 2014-06-29]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
A whole-brain atlas of inputs to serotonergic neurons of the dorsal and median raphe nuclei.
Pollak Dorocic I, Fürth D, Xuan Y, ..., Carlén M, Meletis K
Neuron 83 (3) 663-678 [2014-08-06; online 2014-08-08]
Iskra Pollak Dorocic SciLifeLab Fellow
PubMed DOI Crossref
Inhibition of tumor-derived prostaglandin-e2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activity.
Mao Y, Sarhan D, Steven A, ..., Kiessling R, Lundqvist A
Clin. Cancer Res. 20 (15) 4096-4106 [2014-08-01; online 2014-06-06]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Tumour-induced immune suppression: role of inflammatory mediators released by myelomonocytic cells.
Mao Y, Poschke I, Kiessling R
J. Intern. Med. 276 (2) 154-170 [2014-08-00; online 2014-03-24]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Spatial control of membrane receptor function using ligand nanocalipers.
Shaw A, Lundin V, Petrova E, ..., Högberg B, Teixeira AI
Nat. Methods 11 (8) 841-846 [2014-08-00; online 2014-07-06]
Erik Benson SciLifeLab Fellow
PubMed DOI Crossref
Epithelium-Intrinsic NAIP/NLRC4 Inflammasome Drives Infected Enterocyte Expulsion to Restrict Salmonella Replication in the Intestinal Mucosa
Sellin ME, Müller AA, Felmy B, ..., Maslowski KM, Hardt WD
Cell Host & Microbe 16 (2) 237-248 [2014-08-00; online 2014-08-00]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Overexpression of sigma factor SigB improves temperature and butanol tolerance of Synechocystis sp. PCC6803.
Kaczmarzyk D, Anfelt J, Särnegrim A, Hudson EP
J. Biotechnol. 182-183 (-) 54-60 [2014-07-20; online 2014-05-05]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Measuring lipid packing of model and cellular membranes with environment sensitive probes.
Sezgin E, Sadowski T, Simons K
Langmuir 30 (27) 8160-8166 [2014-07-15; online 2014-06-30]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
The molecular mode of action of the active component of chili pepper
Elokely K, Palovcak E, Delemotte L, Carnevale V, Klein M
Planta Med 80 (10) - [2014-07-14; online 2014-07-14]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Insecticide resistance in disease vectors from Mayotte: an opportunity for integrated vector management.
Pocquet N, Darriet F, Zumbo B, ..., Labbé P, Chandre F
Parasit Vectors 7 (-) 299 [2014-07-01; online 2014-07-01]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
The use of Genome-scale metabolic models for drug target and biomarker identification
Mardinoglu A, Uhlen M, Nielsen J
New Biotechnology 31 (-) S49 [2014-07-00; online 2014-07-00]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
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Pre-clinical evaluation of [(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4 for imaging of insulinoma.
Selvaraju RK, Velikyan I, Asplund V, ..., Korsgren O, Eriksson O
Nucl. Med. Biol. 41 (6) 471-476 [2014-07-00; online 2014-03-29]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide identification of transcript start and end sites by transcript isoform sequencing
Pelechano V, Wei W, Jakob P, Steinmetz LM
Nat Protoc 9 (7) 1740-1759 [2014-07-00; online 2014-06-26]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
GENE-dosage effects on fitness in recent adaptive duplications: ace-1 in the mosquito Culex pipiens.
Labbé P, Milesi P, Yébakima A, ..., Weill M, Lenormand T
Evolution 68 (7) 2092-2101 [2014-07-00; online 2014-03-20]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
A constrained multi-objective surrogate-based optimization algorithm
Singh P, Couckuyt I, Ferranti F, Dhaene T
- - (-) - [2014-07-00; online 2014-07-00]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
The Marine Microbial Eukaryote Transcriptome Sequencing Project (MMETSP): illuminating the functional diversity of eukaryotic life in the oceans through transcriptome sequencing.
Keeling PJ, Burki F, Wilcox HM, ..., Zingone A, Worden AZ
PLoS Biol. 12 (6) e1001889 [2014-06-00; online 2014-06-24]
Fabien Burki SciLifeLab Fellow
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Development of a 124I-labeled version of the anti-PSMA monoclonal antibody capromab for immunoPET staging of prostate cancer: Aspects of labeling chemistry and biodistribution.
Tolmachev V, Malmberg J, Estrada S, Eriksson O, Orlova A
Int. J. Oncol. 44 (6) 1998-2008 [2014-06-00; online 2014-04-10]
Olof Eriksson SciLifeLab Fellow
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Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits
Piazza I, Rutkowska A, Ori A, ..., Beck M, Haering CH
Nat Struct Mol Biol 21 (6) 560-568 [2014-06-00; online 2014-05-18]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Cell type–specific expression of SEPT3-homology subgroup members controls the subunit number of heteromeric septin complexes
Sellin ME, Stenmark S, Gullberg M
MBoC 25 (10) 1594-1607 [2014-05-15; online 2014-05-15]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
The Eukaryotic Tree of Life from a Global Phylogenomic Perspective
Burki F
Cold Spring Harbor Perspectives in Biology 6 (5) a016147-a016147 [2014-05-01; online 2014-05-01]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Voltage-gated ion channel modulation by lipids: Insights from molecular dynamics simulations
Kasimova MA, Tarek M, Shaytan AK, Shaitan KV, Delemotte L
Biochimica et Biophysica Acta (BBA) - Biomembranes 1838 (5) 1322-1331 [2014-05-00; online 2014-05-00]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Rapid TaqMan-based quantification of chlorophyll d-containing cyanobacteria in the genus Acaryochloris.
Behrendt L, Nielsen JL, Sørensen SJ, ..., Winther JR, Kühl M
Applied and environmental microbiology 80 (10) 3244-3249 [2014-05-00; online 2014-03-14]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal
Elliott TS, Townsley FM, Bianco A, ..., Lilley KS, Chin JW
Nat Biotechnol 32 (5) 465-472 [2014-05-00; online 2014-04-13]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Detection of metastatic insulinoma by positron emission tomography with [(68)ga]exendin-4-a case report.
Eriksson O, Velikyan I, Selvaraju RK, ..., Sörensen J, Korsgren O
J. Clin. Endocrinol. Metab. 99 (5) 1519-1524 [2014-05-00; online 2014-02-10]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Contribution of Network Connectivity in Determining the Relationship between Gene Expression and Metabolite Concentration Changes
Zelezniak A, Sheridan S, Patil KR
PLoS Comput Biol 10 (4) e1003572 [2014-04-24; online 2014-04-24]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
Evidence for the biogenesis of more than 1,000 novel human microRNAs.
Friedländer MR, Lizano E, Houben AJ, ..., Martí E, Estivill X
Genome Biol. 15 (4) R57 [2014-04-07; online 2014-04-07]
Marc Friedländer SciLifeLab Fellow
DOI Crossref
Evidence of Conducting Hydrophobic Nanopores Across Membranes in Response to an Electric Field
Dehez F, Delemotte L, Kramar P, Miklavčič D, Tarek M
J. Phys. Chem. C 118 (13) 6752-6757 [2014-04-03; online 2014-03-19]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Transcription Factor Activating Protein-2β (TFAP-2β) genotype and symptoms of attention deficit hyperactivity disorder in relation to symptoms of depression in two independent samples.
Nilsson KW, Sonnby K, Nordquist N, ..., Oreland L, Sjöberg RL
Eur Child Adolesc Psychiatry 23 (4) 207-217 [2014-04-00; online 2013-07-04]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
To divide or not to divide: control of the bacterial cell cycle by environmental cues
Jonas K
Current Opinion in Microbiology 18 (-) 54-60 [2014-04-00; online 2014-04-00]
Kristina Jonas SciLifeLab Fellow
DOI Crossref
Enhanced greenhouse gas emissions and changes in plankton communities following an experimental increase in organic carbon loading to a humic lake
Peura S, Nykänen H, Kankaala P, ..., Tiirola M, Jones RI
Biogeochemistry 118 (1-3) 177-194 [2014-04-00; online 2013-10-16]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
DAXX co-folds with H3.3/H4 using high local stability conferred by the H3.3 variant recognition residues
DeNizio JE, Elsässer SJ, Black BE
Nucleic Acids Res. 42 (7) 4318-4331 [2014-04-00; online 2014-01-31]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Structure of the Yeast Mitochondrial Large Ribosomal Subunit
Amunts A, Brown A, Bai Xc, ..., Scheres SHW, Ramakrishnan V
Science 343 (6178) 1485-1489 [2014-03-28; online 2014-03-27]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Alternative polyadenylation diversifies post-transcriptional regulation by selective RNA-protein interactions
Gupta I, Clauder-Munster S, Klaus B, ..., Pelechano V, Steinmetz LM
Mol Syst Biol 10 (2) 719-719 [2014-03-20; online 2014-02-25]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Two-Color RESOLFT Nanoscopy with Green and Red Fluorescent Photochromic Proteins
Lavoie-Cardinal F, Jensen NA, Westphal V, ..., Jakobs S, Hell SW
ChemPhysChem 15 (4) 655-663 [2014-03-17; online 2014-01-21]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Myeloid suppressors decrease melanoma survival by abating tumor-fighting T cells.
Kiessling R, Mao Y, Pico de Coaña Y
Clin. Cancer Res. 20 (6) 1401-1403 [2014-03-15; online 2014-02-13]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
A Generic Method for Design of Oligomer-Specific Antibodies
Brännström K, Lindhagen-Persson M, Gharibyan AL, ..., Forsgren L, Olofsson A
PLoS ONE 9 (3) e90857 [2014-03-11; online 2014-03-11]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Quantitative imaging of serotonergic biosynthesis and degradation in the endocrine pancreas.
Eriksson O, Selvaraju RK, Johansson L, ..., Eriksson B, Korsgren O
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 55 (3) 460-465 [2014-03-00; online 2014-02-13]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
A Cyclic Nucleotide-Gated Channel Mutation Associated with Canine Daylight Blindness Provides Insight into a Role for the S2 Segment Tri-Asp motif in Channel Biogenesis
Tanaka N, Delemotte L, Klein ML, Komáromy AM, Tanaka JC
PLoS ONE 9 (2) e88768 [2014-02-21; online 2014-02-21]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Genetic Encoding of Photocaged Cysteine Allows Photoactivation of TEV Protease in Live Mammalian Cells
Nguyen DP, Mahesh M, Elsässer SJ, ..., Uttamapinant C, Chin JW
J. Am. Chem. Soc. 136 (6) 2240-2243 [2014-02-12; online 2014-01-30]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Rhizaria.
Burki F, Keeling PJ
Curr. Biol. 24 (3) R103-R107 [2014-02-03; online 2014-02-08]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Successful enrichment of the ubiquitous freshwater acI Actinobacteria.
Garcia SL, McMahon KD, Grossart HP, Warnecke F
Environ Microbiol Rep 6 (1) 21-27 [2014-02-00; online 2013-11-10]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Mitigating aggressiveness through education? The monoamine oxidase A genotype and mental health in general population.
Kiive E, Laas K, Akkermann K, ..., Veidebaum T, Harro J
Acta Neuropsychiatr 26 (1) 19-28 [2014-02-00; online 2014-08-22]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Imaging of platelet-derived growth factor receptor β expression in glioblastoma xenografts using affibody molecule 111In-DOTA-Z09591.
Tolmachev V, Varasteh Z, Honarvar H, ..., Abrahmsen L, Orlova A
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 55 (2) 294-300 [2014-02-00; online 2014-01-09]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Evolutionary imprint of activation: The design principles of VSDs
Palovcak E, Delemotte L, Klein ML, Carnevale V
J Gen Physiol 143 (2) 145-156 [2014-02-00; online 2014-01-27]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Endosymbiotic Gene Transfer in Tertiary Plastid-Containing Dinoflagellates
Burki F, Imanian B, Hehenberger E, ..., Maruyama S, Keeling PJ
Eukaryotic Cell 13 (2) 246-255 [2014-02-00; online 2013-12-02]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Distribution of acI-Actinorhodopsin genes in Baltic Sea salinity gradients indicates adaptation of facultative freshwater photoheterotrophs to brackish waters.
Salka I, Wurzbacher C, Garcia SL, ..., Jürgens K, Grossart HP
Environ. Microbiol. 16 (2) 586-597 [2014-02-00; online 2013-07-10]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Wolbachia divergence and the evolution of cytoplasmic incompatibility in Culex pipiens.
Atyame CM, Labbé P, Dumas E, ..., Fort P, Weill M
PLoS ONE 9 (1) e87336 [2014-01-31; online 2014-01-31]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Immunological shielding by induced recruitment of regulatory T-lymphocytes delays rejection of islets transplanted in muscle.
Vågesjö E, Christoffersson G, Waldén TB, ..., Korsgren O, Phillipson M
Cell Transplant 24 (2) 263-276 [2014-01-29; online 2014-01-29]
Gustaf Christoffersson SciLifeLab Fellow
DOI Crossref
Effect of size, composition, and morphology on magnetic performance: First-order reversal curves evaluation of iron oxide nanoparticles
Hirt AM, Sotiriou GA, Kidambi PR, Teleki A
Journal of Applied Physics 115 (4) 044314 [2014-01-28; online 2014-01-28]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Mice lacking NMDA receptors in parvalbumin neurons display normal depression-related behavior and response to antidepressant action of NMDAR antagonists.
Pozzi L, Pollak Dorocic I, Dorocic IP, ..., Carlén M, Meletis K
PLoS ONE 9 (1) e83879 [2014-01-16; online 2014-01-16]
Iskra Pollak Dorocic SciLifeLab Fellow
PubMed DOI Crossref
HSF1 at a glance.
Vihervaara A, Sistonen L
J. Cell. Sci. 127 (Pt 2) 261-266 [2014-01-15; online 2014-01-15]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men.
Benedict C, Cedernaes J, Giedraitis V, ..., Zetterberg H, Schiöth HB
Sleep 37 (1) 195-198 [2014-01-01; online 2014-01-01]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
On the use of [18F]DOPA as an imaging biomarker for transplanted islet mass.
Eriksson O, Mintz A, Liu C, ..., Naji A, Alavi A
Annals of nuclear medicine 28 (1) 47-52 [2014-01-00; online 2013-10-29]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
FuseFISH: Robust Detection of Transcribed Gene Fusions in Single Cells
Semrau S, Crosetto N, Bienko M, ..., Chiarle R, van Oudenaarden A
Cell Reports 6 (1) 18-23 [2014-01-00; online 2014-01-00]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Dynamic remodeling of histone modifications in response to osmotic stress in Saccharomyces cerevisiae
Magraner-Pardo L, Pelechano V, Coloma M, Tordera V
BMC Genomics 15 (1) 247 [2014-00-00; online 2014-00-00]
SciLifeLab Fellow Vicente Pelechano

Year 2013

PubMed DOI Crossref
Omega Currents in Voltage-Gated Ion Channels: What Can We Learn from Uncovering the Voltage-Sensing Mechanism Using MD Simulations?
Tarek M, Delemotte L
Acc. Chem. Res. 46 (12) 2755-2762 [2013-12-17; online 2013-05-22]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Bile acids modulate signaling by functional perturbation of plasma membrane domains.
Zhou Y, Maxwell KN, Sezgin E, ..., Lichtenberger LM, Levental I
J Biol Chem 288 (50) 35660-35670 [2013-12-13; online 2013-10-28]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Understanding the interactions between bacteria in the human gut through metabolic modeling
Shoaie S, Karlsson F, Mardinoglu A, ..., Bordel S, Nielsen J
Sci Rep 3 (1) - [2013-12-00; online 2013-08-28]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Imaging the in vivo fate of human T cells following transplantation in immunoincompetent mice - implications for clinical cell therapy trials.
Berglund D, Karlsson M, Palanisamy S, ..., Korsgren O, Eriksson O
Transplant immunology 29 (1-4) 105-108 [2013-12-00; online 2013-09-29]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Gene regulation by antisense transcription
Pelechano V, Steinmetz LM
Nat Rev Genet 14 (12) 880-893 [2013-12-00; online 2013-11-12]
SciLifeLab Fellow Vicente Pelechano
DOI Crossref
Accurate Hotspot Localization by Sampling the Near-Field Pattern of Electronic Devices
Singh P, Deschrijver D, Pissoort D, Dhaene T
IEEE Trans. Electromagn. Compat. 55 (6) 1365-1368 [2013-12-00; online 2013-12-00]
Prashant Singh SciLifeLab Fellow
DOI Crossref
A balanced sequential design strategy for global surrogate modeling
Singh P, Deschrijver D, Dhaene T
- - (-) - [2013-12-00; online 2013-12-00]
Prashant Singh SciLifeLab Fellow
DOI Crossref
Thermal Energy Dissipation by SiO2-Coated Plasmonic-Superparamagnetic Nanoparticles in Alternating Magnetic Fields
Sotiriou GA, Visbal-Onufrak MA, Teleki A, ..., Pratsinis SE, Rinaldi C
Chem Mater 25 (22) 4603-4612 [2013-11-26; online 2013-11-07]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Tumor-dependent increase of serum amino acid levels in breast cancer patients has diagnostic potential and correlates with molecular tumor subtypes.
Poschke I, Mao Y, Kiessling R, de Boniface J
J Transl Med 11 (-) 290 [2013-11-16; online 2013-11-16]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression.
Culverhouse RC, Bowes L, Breslau N, ..., Bierut LJ, 5-HTTLPR, Stress, and Depression Consortium
BMC Psychiatry 13 (-) 304 [2013-11-12; online 2013-11-12]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Adaptive classification algorithm for EMC‐compliance testing of electronic devices
Singh P, Deschrijver D, Pissoort D, Dhaene T
Electron. lett. 49 (24) 1526-1528 [2013-11-00; online 2013-11-00]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Multiple insecticide resistances in the disease vector Culex p. quinquefasciatus from Western Indian Ocean.
Pocquet N, Milesi P, Makoundou P, ..., Chandre F, Labbé P
PLoS ONE 8 (10) e77855 [2013-10-21; online 2013-10-21]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Neuropsychiatric deep brain stimulation for translational neuroimaging.
Höflich A, Savli M, Comasco E, ..., Kasper S, Lanzenberger R
NeuroImage 79 (-) 30-41 [2013-10-01; online 2013-04-28]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Three-way interaction effect of 5-HTTLPR, BDNF Val66Met, and childhood adversity on depression: a replication study.
Comasco E, Åslund C, Oreland L, Nilsson KW
Eur Neuropsychopharmacol 23 (10) 1300-1306 [2013-10-00; online 2013-03-06]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Adipocytokines levels at delivery, functional variation of TFAP2β, and maternal and neonatal anthropometric parameters.
Comasco E, Iliadis SI, Larsson A, ..., Sundström-Poromaa I, Skalkidou A
Obesity (Silver Spring) 21 (10) 2130-2137 [2013-10-00; online 2013-05-29]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells.
Vihervaara A, Sergelius C, Vasara J, ..., Roos-Mattjus P, Sistonen L
Proc. Natl. Acad. Sci. U.S.A. 110 (36) E3388-E3397 [2013-09-03; online 2013-08-19]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Population structure of Wolbachia and cytoplasmic introgression in a complex of mosquito species.
Dumas E, Atyame CM, Milesi P, ..., Weill M, Duron O
BMC Evol Biol BMC Evolutionary Biology 13 (-) 181 [2013-09-03; online 2013-09-03]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Ipilimumab treatment results in an early decrease in the frequency of circulating granulocytic myeloid-derived suppressor cells as well as their Arginase1 production.
Pico de Coaña Y, Poschke I, Gentilcore G, ..., Masucci GV, Kiessling R
Cancer Immunol Res 1 (3) 158-162 [2013-09-00; online 2013-08-02]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Hira-Dependent Histone H3.3 Deposition Facilitates PRC2 Recruitment at Developmental Loci in ES Cells
Banaszynski LA, Wen D, Dewell S, ..., Zheng D, Allis CD
Cell 155 (1) 107-120 [2013-09-00; online 2013-09-00]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Genome-scale modeling of human metabolism - a systems biology approach
Mardinoglu A, Gatto F, Nielsen J
Biotechnology Journal 8 (9) 985-996 [2013-09-00; online 2013-04-24]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Lypd6 enhances Wnt/β-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains.
Özhan G, Sezgin E, Wehner D, ..., Schwille P, Weidinger G
Dev. Cell 26 (4) 331-345 [2013-08-26; online 2013-08-31]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Proteotoxic Stress Induces a Cell-Cycle Arrest by Stimulating Lon to Degrade the Replication Initiator DnaA
Jonas K, Liu J, Chien P, Laub MT
Cell 154 (3) 623-636 [2013-08-00; online 2013-08-00]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Polyadenylation site–induced decay of upstream transcripts enforces promoter directionality
Ntini E, Järvelin AI, Bornholdt J, ..., Sandelin A, Jensen TH
Nat Struct Mol Biol 20 (8) 923-928 [2013-08-00; online 2013-07-14]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Phylogenomics of the Intracellular Parasite Mikrocytos mackini Reveals Evidence for a Mitosome in Rhizaria
Burki F, Corradi N, Sierra R, ..., Abbott CL, Keeling PJ
Current Biology 23 (16) 1541-1547 [2013-08-00; online 2013-08-00]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
MicroRNA expression profiling in blood from fragile X-associated tremor/ataxia syndrome patients
Alvarez-Mora MI, Rodriguez-Revenga L, Madrigal I, ..., Estivill X, Milà M
- 12 (6) 595-603 [2013-08-00; online 2013-07-24]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
In vivo imaging of the glucagonlike peptide 1 receptor in the pancreas with 68Ga-labeled DO3A-exendin-4.
Selvaraju RK, Velikyan I, Johansson L, ..., Korsgren O, Eriksson O
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 54 (8) 1458-1463 [2013-08-00; online 2013-06-12]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Depth-discrete profiles of bacterial communities reveal pronounced spatio-temporal dynamics related to lake stratification.
Garcia SL, Salka I, Grossart HP, Warnecke F
Environ Microbiol Rep 5 (4) 549-555 [2013-08-00; online 2013-03-18]
Sarahi Garcia SciLifeLab Fellow
DOI Crossref
Cyclooxygenase-2
Mao Y, Poschke I, Kiessling R
Oncoimmunology 2 (8) e25157 [2013-08-00; online 2014-10-27]
SciLifeLab Fellow Yumeng Mao
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Structure-based Discovery of Antagonists of Nuclear Receptor LRH-1
Benod C, Carlsson J, Uthayaruban R, ..., Sablin EP, Fletterick RJ
J. Biol. Chem. 288 (27) 19830-19844 [2013-07-05; online 2013-05-10]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Melanoma-educated CD14+ cells acquire a myeloid-derived suppressor cell phenotype through COX-2-dependent mechanisms.
Mao Y, Poschke I, Wennerberg E, ..., Lundqvist A, Kiessling R
Cancer Res. 73 (13) 3877-3887 [2013-07-01; online 2013-04-30]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Upregulation of a small vault RNA (svtRNA2-1a) is an early event in Parkinson disease and induces neuronal dysfunction.
Miñones-Moyano E, Friedländer MR, Pallares J, ..., Estivill X, Martí E
RNA Biol 10 (7) 1093-1106 [2013-07-00; online 2013-05-01]
Marc Friedländer SciLifeLab Fellow
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Influence of catechol-O-methyltransferase Val158Met polymorphism on startle response in the presence of high estradiol levels.
Comasco E, Hellgren C, Sundström-Poromaa I
Eur Neuropsychopharmacol 23 (7) 629-635 [2013-07-00; online 2012-07-23]
Erika Comasco SciLifeLab Fellow
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A common structural theme in histone chaperones mimics interhistone contacts.
Elsässer SJ
Trends Biochem. Sci. 38 (7) 333-336 [2013-07-00; online 2013-06-26]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Structural Basis for Activation of ZAP-70 by Phosphorylation of the SH2-Kinase Linker
Yan Q, Barros T, Visperas PR, ..., Weiss A, Kuriyan J
Molecular and Cellular Biology 33 (11) 2188-2201 [2013-06-01; online 2013-03-25]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
Serotonin transporter genotype by environment: Studies on alcohol use and misuse in non-human and human primates
Todkar A, Nilsson K, Oreland L, Hodgins S, Comasco E
- 4 (2) 241-250 [2013-06-01; online 2013-06-09]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Quantitative insights into actin rearrangements and bacterial target site selection from Salmonella Typhimurium infection of micropatterned cells
Vonaesch P, Cardini S, Sellin ME, ..., Hardt WD, Schauer K
Cell Microbiol - (-) n/a-n/a [2013-06-00; online 2013-05-30]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Mechanistic Insights into the LsrK Kinase Required for Autoinducer-2 Quorum Sensing Activation
Zhu J, Hixon MS, Globisch D, Kaufmann GF, Janda KD
J. Am. Chem. Soc. 135 (21) 7827-7830 [2013-05-29; online 2013-05-16]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Role of aspartate 132 at the orifice of a proton pathway in cytochrome c oxidase
Johansson AL, Hogbom M, Carlsson J, Gennis RB, Brzezinski P
Proceedings of the National Academy of Sciences 110 (22) 8912-8917 [2013-05-28; online 2013-05-14]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Crystal structure of the complex between prokaryotic ubiquitin-like protein and its ligase PafA.
Barandun J, Delley CL, Ban N, Weber-Ban E
J. Am. Chem. Soc. 135 (18) 6794-6797 [2013-05-08; online 2013-04-23]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Molecular Characterization of Parabasalian Symbionts Coronympha clevelandii and Trichonympha subquasilla from the Hawaiian Lowland Tree Termite Incisitermes immigrans
James ER, Burki F, Todd Harper J, Scheffrahn RH, Keeling PJ
J. Eukaryot. Microbiol. 60 (3) 313-316 [2013-05-00; online 2013-02-05]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile.
Lundberg K, Bengtsson C, Kharlamova N, ..., Alfredsson L, Klareskog L
Ann. Rheum. Dis. 72 (5) 652-658 [2013-05-00; online 2012-06-01]
Iskra Pollak Dorocic SciLifeLab Fellow
PubMed DOI Crossref
5-Fluoro-[β-¹¹C]-L-tryptophan is a functional analogue of 5-hydroxy-[β-¹¹C]-L-tryptophan in vitro but not in vivo.
Eriksson O, Selvaraju R, Borg B, ..., Estrada S, Antoni G
Nucl. Med. Biol. 40 (4) 567-575 [2013-05-00; online 2013-03-22]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Extensive transcriptional heterogeneity revealed by isoform profiling
Pelechano V, Wei W, Steinmetz LM
Nature 497 (7447) 127-131 [2013-04-24; online 2013-04-24]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Photoconversion of bodipy-labeled lipid analogues.
Sezgin E, Chwastek G, Aydogan G, ..., Simons K, Schwille P
Chembiochem 14 (6) 695-698 [2013-04-15; online 2013-03-19]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Conduction in a Biological Sodium Selective Channel
Stock L, Delemotte L, Carnevale V, Treptow W, Klein ML
J. Phys. Chem. B 117 (14) 3782-3789 [2013-04-11; online 2013-03-27]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing.
Crosetto N, Mitra A, Silva MJ, ..., Rowicka M, Dikic I
Nat. Methods 10 (4) 361-365 [2013-04-00; online 2013-03-17]
Affiliated researcher Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Global profiling of miRNAs and the hairpin precursors: insights into miRNA processing and novel miRNA discovery
Li N, You X, Chen T, ..., Hu Y, Chen W
Nucleic Acids Res. 41 (6) 3619-3634 [2013-04-00; online 2013-02-08]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Effect of gene, environment and maternal depressive symptoms on pre-adolescence behavior problems - a longitudinal study.
Agnafors S, Comasco E, Bladh M, ..., Oreland L, Svedin CG
Child Adolesc Psychiatry Ment Health 7 (1) 10 [2013-03-22; online 2013-03-22]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Green sulphur bacteria as a component of the photosynthetic plankton community in small dimictic humic lakes with an anoxic hypolimnion
Karhunen J, Arvola L, Peura S, Tiirola M
Aquat. Microb. Ecol. 68 (3) 267-272 [2013-03-18; online 2013-03-18]
Sari Peura SciLifeLab Fellow
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Global Gene Expression Profiling Reveals SPINK1 as a Potential Hepatocellular Carcinoma Marker
Marshall A, Lukk M, Kutter C, ..., Alexander G, Odom DT
PLoS ONE 8 (3) e59459 [2013-03-18; online 2013-03-18]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Cthulhu Macrofasciculumque n. g., n. sp. and Cthylla Microfasciculumque n. g., n. sp., a Newly Identified Lineage of Parabasalian Termite Symbionts
James ER, Okamoto N, Burki F, Scheffrahn RH, Keeling PJ
PLoS ONE 8 (3) e58509 [2013-03-18; online 2013-03-18]
Fabien Burki SciLifeLab Fellow
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Onchocerca volvulus-neurotransmitter tyramine is a biomarker for river blindness
Globisch D, Moreno AY, Hixon MS, ..., Hoerauf A, Janda KD
Proceedings of the National Academy of Sciences 110 (11) 4218-4223 [2013-03-12; online 2013-02-25]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
An efficient method for genome-wide polyadenylation site mapping and RNA quantification
Wilkening S, Pelechano V, Järvelin AI, ..., Benes V, Steinmetz LM
Nucleic Acids Res. 41 (5) e65-e65 [2013-03-01; online 2013-01-07]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates
Long HK, Sims D, Heger A, ..., Ponting CP, Klose RJ
Elife 2 (-) - [2013-02-26; online 2013-02-26]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Reactive oxygen production induced by near-infrared radiation in three strains of the Chl d-containing cyanobacterium Acaryochloris marina.
Behrendt L, Staal M, Cristescu SM, ..., Larkum AW, Kühl M
F1000Res 2 (-) 44 [2013-02-13; online 2013-02-13]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Specific inhibition of caspase-3 by a competitive DARPin: molecular mimicry between native and designed inhibitors.
Schroeder T, Barandun J, Flütsch A, ..., Mittl PR, Grütter MG
Structure 21 (2) 277-289 [2013-02-05; online 2013-01-17]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Proton Uptake and pKa Changes in the Uncoupled Asn139Cys Variant of Cytochrome c Oxidase
Johansson AL, Carlsson J, Högbom M, ..., Gennis RB, Brzezinski P
Biochemistry 52 (5) 827-836 [2013-02-05; online 2013-01-25]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
β-Cell mass imaging with DTBZ positron emission tomography: is it possible?
Blomberg BA, Eriksson O, Saboury B, Alavi A
Molecular imaging and biology 15 (1) 1-2 [2013-02-00; online 2012-09-18]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Nucleosome mobilization by ISW2 requires the concerted action of the ATPase and SLIDE domains
Hota SK, Bhardwaj SK, Deindl S, ..., Zhuang X, Bartholomew B
Nat Struct Mol Biol 20 (2) 222-229 [2013-02-00; online 2013-01-20]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
A versatile genome-scale PCR-based pipeline for high-definition DNA FISH
Bienko M, Crosetto N, Teytelman L, ..., Itzkovitz S, van Oudenaarden A
Nat Methods 10 (2) 122-124 [2013-02-00; online 2012-12-23]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Target selectivity of feedforward inhibition by striatal fast-spiking interneurons.
Szydlowski SN, Pollak Dorocic I, Planert H, ..., Meletis K, Silberberg G
J. Neurosci. 33 (4) 1678-1683 [2013-01-23; online 2013-01-25]
Iskra Pollak Dorocic SciLifeLab Fellow
PubMed DOI Crossref
Unveiling Distribution Patterns of Freshwater Phytoplankton by a Next Generation Sequencing Based Approach
Eiler A, Drakare S, Bertilsson S, ..., Znachor P, Lindström ES
PLoS ONE 8 (1) e53516 [2013-01-22; online 2013-01-22]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Self-reported family socioeconomic status, the 5-HTTLPR genotype, and delinquent behavior in a community-based adolescent population.
Aslund C, Comasco E, Nordquist N, ..., Oreland L, Nilsson KW
Aggress Behav 39 (1) 52-63 [2013-01-00; online 2012-09-14]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Metabolic potential of a single cell belonging to one of the most abundant lineages in freshwater bacterioplankton.
Garcia SL, McMahon KD, Martinez-Garcia M, ..., Woyke T, Warnecke F
ISME J 7 (1) 137-147 [2013-01-00; online 2012-07-19]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Latent Regulatory Potential of Human-Specific Repetitive Elements
Ward MC, Wilson MD, Barbosa-Morais NL, ..., Blencowe BJ, Odom DT
Molecular Cell 49 (2) 262-272 [2013-01-00; online 2013-01-00]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
ISWI Remodelers Slide Nucleosomes with Coordinated Multi-Base-Pair Entry Steps and Single-Base-Pair Exit Steps
Deindl S, Hwang WL, Hota SK, ..., Bartholomew B, Zhuang X
Cell 152 (3) 442-452 [2013-01-00; online 2013-01-00]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells.
Zang G, Christoffersson G, Tian G, ..., Tengholm A, Welsh M
Cell. Signal. 25 (1) 85-92 [2013-01-00; online 2012-09-18]
Gustaf Christoffersson SciLifeLab Fellow
DOI Crossref
100 Years of Vitamins: The Science of Formulation is the Key to Functionality
Teleki A, Hitzfeld A, Eggersdorfer M
KONA 30 (0) 144-163 [2013-00-00; online 2013-00-00]
Alexandra Teleki SciLifeLab Fellow

Year 2012

PubMed DOI Crossref
The Evolutionary Landscape of Alternative Splicing in Vertebrate Species
Barbosa-Morais NL, Irimia M, Pan Q, ..., Frey BJ, Blencowe BJ
Science 338 (6114) 1587-1593 [2012-12-21; online 2012-12-20]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
The effect of premenstrual dysphoric disorder and menstrual cycle phase on brain activity during response inhibition.
Bannbers E, Gingnell M, Engman J, ..., Wikström J, Sundström Poromaa I
J Affect Disord 142 (1-3) 347-350 [2012-12-15; online 2012-07-27]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Dual targeting of aminoacyl-tRNA synthetases to the mitochondrion and complex plastid in chlorarachniophytes
Hirakawa Y, Burki F, Keeling PJ
Journal of Cell Science 125 (24) 6176-6184 [2012-12-15; online 2012-10-04]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs
Curtis BA, Tanifuji G, Burki F, ..., Grigoriev IV, Archibald JM
Nature 492 (7427) 59-65 [2012-12-00; online 2012-11-28]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
The pupylation pathway and its role in mycobacteria.
Barandun J, Delley CL, Weber-Ban E
BMC Biol. 10 (-) 95 [2012-11-30; online 2012-11-30]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Microenvironmental Ecology of the Chlorophyll b-Containing Symbiotic Cyanobacterium Prochloron in the Didemnid Ascidian Lissoclinum patella.
Kühl M, Behrendt L, Trampe E, ..., Klimant I, Larkum AW
Front Microbiol 3 (-) 402 [2012-11-30; online 2012-11-30]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
VEGF-A recruits a proangiogenic MMP-9-delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissue.
Christoffersson G, Vågesjö E, Vandooren J, ..., Opdenakker G, Phillipson M
Blood 120 (23) 4653-4662 [2012-11-29; online 2012-09-10]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Gating pore currents and the resting state of Nav1.4 voltage sensor domains
Gosselin-Badaroudine P, Delemotte L, Moreau A, Klein ML, Chahine M
Proceedings of the National Academy of Sciences 109 (47) 19250-19255 [2012-11-20; online 2012-11-07]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Expression patterns of the immunomodulatory enzyme arginase 1 in blood, lymph nodes and tumor tissue of early-stage breast cancer patients.
de Boniface J, Mao Y, Schmidt-Mende J, Kiessling R, Poschke I
Oncoimmunology 1 (8) 1305-1312 [2012-11-01; online 2012-12-18]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Mammalian SEPT9 isoforms direct microtubule-dependent arrangements of septin core heteromers
Sellin ME, Stenmark S, Gullberg M
MBoC 23 (21) 4242-4255 [2012-11-00; online 2012-11-00]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
DAXX envelops a histone H3.3–H4 dimer for H3.3-specific recognition
Elsässer SJ, Huang H, Lewis PW, ..., Allis CD, Patel DJ
Nature 491 (7425) 560-565 [2012-11-00; online 2012-10-17]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Biological aspects of postpartum depression.
Skalkidou A, Hellgren C, Comasco E, Sylvén S, Sundström Poromaa I
Womens Health (Lond) 8 (6) 659-672 [2012-11-00; online 2012-11-28]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Isotope-Based Analysis of Modified tRNA Nucleosides Correlates Modification Density with Translational Efficiency
Brandmayr C, Wagner M, Brückl T, ..., Biel M, Carell T
Angewandte Chemie International Edition 51 (44) 11162-11165 [2012-10-29; online 2012-10-04]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
DNA origami delivery system for cancer therapy with tunable release properties.
Zhao Y, Shaw A, Zeng X, ..., Nyström AM, Högberg B
ACS Nano 6 (10) 8684-8691 [2012-10-23; online 2012-09-13]
Erik Benson SciLifeLab Fellow
PubMed DOI Crossref
Sustained beta-cell dysfunction but normalized islet mass in aged thrombospondin-1 deficient mice.
Drott CJ, Olerud J, Emanuelsson H, Christoffersson G, Carlsson PO
PLoS ONE 7 (10) e47451 [2012-10-19; online 2012-10-19]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Dual Effect of Phosphatidyl (4,5)-Bisphosphate PIP2on Shaker K+Channels
Abderemane-Ali F, Es-Salah-Lamoureux Z, Delemotte L, ..., Baró I, Loussouarn G
J. Biol. Chem. 287 (43) 36158-36167 [2012-10-19; online 2012-08-29]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Tumor-induced changes in the phenotype of blood-derived and tumor-associated T cells of early stage breast cancer patients.
Poschke I, De Boniface J, Mao Y, Kiessling R
Int. J. Cancer 131 (7) 1611-1620 [2012-10-01; online 2012-01-31]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Opposing consequences of signaling through EGF family members: Escape from CTLs could be a bait for NK cells.
Kiessling R, Okita R, Mougiakakos D, ..., Mimura K, Kono K
Oncoimmunology 1 (7) 1200-1201 [2012-10-01; online 2012-11-22]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Low values of 5-hydroxymethylcytosine (5hmC), the “sixth base,” are associated with anaplasia in human brain tumors
Kraus TFJ, Globisch D, Wagner M, ..., Carell T, Kretzschmar HA
Int. J. Cancer 131 (7) 1577-1590 [2012-10-01; online 2012-03-02]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Molecular-Level Characterization of Lipid Membrane Electroporation using Linearly Rising Current
Kramar P, Delemotte L, Maček Lebar A, ..., Tarek M, Miklavčič D
J Membrane Biol 245 (10) 651-659 [2012-10-00; online 2012-08-11]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Alcohol consumption among pregnant women in a Swedish sample and its effects on the newborn outcomes.
Comasco E, Hallberg G, Helander A, Oreland L, Sundelin-Wahlsten V
Alcohol Clin Exp Res 36 (10) 1779-1786 [2012-10-00; online 2012-04-06]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Structure–Activity Relationships and Molecular Modeling of 1,2,4-Triazoles as Adenosine Receptor Antagonists
Carlsson J, Tosh DK, Phan K, Gao ZG, Jacobson KA
ACS Med. Chem. Lett. 3 (9) 715-720 [2012-09-13; online 2012-08-07]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency.
Christoffersson G, Zang G, Zhuang ZW, ..., Phillipson M, Welsh M
Angiogenesis 15 (3) 469-480 [2012-09-00; online 2012-05-05]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
The Revised Classification of Eukaryotes
Adl SM, Simpson AGB, Lane CE, ..., Smirnov A, Spiegel FW
J. Eukaryot. Microbiol. 59 (5) 429-514 [2012-09-00; online 2012-09-28]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Nanoscopy of Living Brain Slices with Low Light Levels
Testa I, Urban NT, Jakobs S, ..., Willig KI, Hell SW
Neuron 75 (6) 992-1000 [2012-09-00; online 2012-09-00]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Molecular Dynamics Simulations of Lipid Membrane Electroporation
Delemotte L, Tarek M
J Membrane Biol 245 (9) 531-543 [2012-09-00; online 2012-05-30]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Intragenomic Spread of Plastid-Targeting Presequences in the Coccolithophore Emiliania huxleyi
Burki F, Hirakawa Y, Keeling PJ
Mol. Biol. Evol. 29 (9) 2109-2112 [2012-09-00; online 2012-03-30]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Distinct and diverse anaerobic bacterial communities in boreal lakes dominated by candidate division OD1
Peura S, Eiler A, Bertilsson S, ..., Tiirola M, Jones RI
ISME J 6 (9) 1640-1652 [2012-09-00; online 2012-03-15]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide polyadenylation site mapping.
Pelechano V, Wilkening S, Järvelin AI, Tekkedil MM, Steinmetz LM
Meth. Enzymol. 513 (-) 271-296 [2012-08-30; online 2012-08-30]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Transport of siRNA through Lipid Membranes Driven by Nanosecond Electric Pulses: An Experimental and Computational Study
Breton M, Delemotte L, Silve A, Mir LM, Tarek M
J. Am. Chem. Soc. 134 (34) 13938-13941 [2012-08-29; online 2012-08-16]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Functional convergence of hopanoids and sterols in membrane ordering.
Sáenz JP, Sezgin E, Schwille P, Simons K
Proc. Natl. Acad. Sci. U.S.A. 109 (35) 14236-14240 [2012-08-28; online 2012-08-14]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Structures of Pup ligase PafA and depupylase Dop from the prokaryotic ubiquitin-like modification pathway.
Özcelik D, Barandun J, Schmitz N, ..., Ban N, Weber-Ban E
Nat Commun 3 (-) 1014 [2012-08-23; online 2012-08-23]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Tertiary Endosymbiosis in Two Dinotoms Has Generated Little Change in the Mitochondrial Genomes of Their Dinoflagellate Hosts and Diatom Endosymbionts
Imanian B, Pombert JF, Dorrell RG, Burki F, Keeling PJ
PLoS ONE 7 (8) e43763 [2012-08-20; online 2012-08-20]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Large-Scale Identification of MicroRNA Targets in Murine Dgcr8-Deficient Embryonic Stem Cell Lines
Davis MPA, Abreu-Goodger C, van Dongen S, ..., Enright AJ, Dunham I
PLoS ONE 7 (8) e41762 [2012-08-17; online 2012-08-17]
Claudia Kutter SciLifeLab Fellow
DOI Crossref
Structural Analysis of Histological Images to Aid Diagnosis of Cervical Cancer
Miranda GHB, Barrera J, Soares EG, Felipe JC
- - (-) 316-323 [2012-08-00; online 2012-08-00]
Gisele Miranda SciLifeLab Fellow
PubMed DOI Crossref
Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events
Liokatis S, Stützer A, Elsässer SJ, ..., Fischle W, Selenko P
Nat Struct Mol Biol 19 (8) 819-823 [2012-08-00; online 2012-07-15]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Model membrane platforms to study protein-membrane interactions.
Sezgin E, Schwille P
Mol. Membr. Biol. 29 (5) 144-154 [2012-08-00; online 2012-07-26]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Gain and loss of multiple functionally related, horizontally transferred genes in the reduced genomes of two microsporidian parasites
Pombert JF, Selman M, Burki F, ..., Corradi N, Keeling PJ
Proceedings of the National Academy of Sciences 109 (31) 12638-12643 [2012-07-31; online 2012-07-16]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Rapid Turnover of Long Noncoding RNAs and the Evolution of Gene Expression
Kutter C, Watt S, Stefflova K, ..., Odom DT, Marques AC
PLoS Genet 8 (7) e1002841 [2012-07-26; online 2012-07-26]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Tumor-dependent down-regulation of the ζ-chain in T-cells is detectable in early breast cancer and correlates with immune cell function.
Boniface JD, Poschke I, Mao Y, Kiessling R
Int. J. Cancer 131 (1) 129-139 [2012-07-01; online 2011-08-30]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Coalescent-Based Analysis Distinguishes between Allo- and Autopolyploid Origin in Shepherd's Purse (Capsella bursa-pastoris)
St. Onge KR, Foxe JP, Li J, ..., Lascoux M, Wright SI
Molecular Biology and Evolution 29 (7) 1721-1733 [2012-07-01; online 2012-01-27]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
The CDK5 repressor CDK5RAP1 is a methylthiotransferase acting on nuclear and mitochondrial RNA
Reiter V, Matschkal DMS, Wagner M, ..., Müller M, Carell T
Nucleic Acids Res. 40 (13) 6235-6240 [2012-07-00; online 2012-03-15]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Rrp6p Controls mRNA Poly(A) Tail Length and Its Decoration with Poly(A) Binding Proteins
Schmid M, Poulsen MB, Olszewski P, ..., Moore C, Jensen TH
Molecular Cell 47 (2) 267-280 [2012-07-00; online 2012-07-00]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes.
Sezgin E, Levental I, Grzybek M, ..., Simons K, Schwille P
Biochim. Biophys. Acta 1818 (7) 1777-1784 [2012-07-00; online 2012-03-28]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Bacterial and Phytoplankton Responses to Nutrient Amendments in a Boreal Lake Differ According to Season and to Taxonomic Resolution
Peura S, Eiler A, Hiltunen M, ..., Tiirola M, Jones RI
PLoS ONE 7 (6) e38552 [2012-06-08; online 2012-06-08]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
The evolutionary history of haptophytes and cryptophytes: phylogenomic evidence for separate origins
Burki F, Okamoto N, Pombert JF, Keeling PJ
Proceedings of the Royal Society B: Biological Sciences 279 (1736) 2246-2254 [2012-06-07; online 2012-02-01]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Collodictyon--An Ancient Lineage in the Tree of Eukaryotes
Zhao S, Burki F, Brate J, ..., Klaveness D, Shalchian-Tabrizi K
Molecular Biology and Evolution 29 (6) 1557-1568 [2012-06-01; online 2012-01-06]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Myeloid-derived suppressor cells impair the quality of dendritic cell vaccines.
Poschke I, Mao Y, Adamson L, ..., Masucci G, Kiessling R
Cancer Immunol. Immunother. 61 (6) 827-838 [2012-06-00; online 2011-11-12]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Microbial diversity of biofilm communities in microniches associated with the didemnid ascidian Lissoclinum patella.
Behrendt L, Larkum AW, Trampe E, ..., Sørensen SJ, Kühl M
ISME J 6 (6) 1222-1237 [2012-06-00; online 2011-12-01]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Biofilm growth and near-infrared radiation-driven photosynthesis of the chlorophyll d-containing cyanobacterium Acaryochloris marina.
Behrendt L, Schrameyer V, Qvortrup K, ..., Larkum AW, Kühl M
Applied and environmental microbiology 78 (11) 3896-3904 [2012-06-00; online 2012-03-30]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Reconstruction of Genome-Scale Active Metabolic Networks for 69 Human Cell Types and 16 Cancer Types Using INIT
Agren R, Bordel S, Mardinoglu A, ..., Nookaew I, Nielsen J
PLoS Comput Biol 8 (5) e1002518 [2012-05-17; online 2012-05-17]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Prediction and identification of sequences coding for orphan enzymes using genomic and metagenomic neighbours
Yamada T, Waller AS, Raes J, ..., Weissenbach J, Bork P
Mol Syst Biol 8 (-) - [2012-05-08; online 2012-05-08]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
Elucidating membrane structure and protein behavior using giant plasma membrane vesicles.
Sezgin E, Kaiser HJ, Baumgart T, ..., Simons K, Levental I
Nat Protoc 7 (6) 1042-1051 [2012-05-03; online 2012-05-03]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Genetic architecture and adaptive significance of the selfing syndrome in Capsella.
Slotte T, Hazzouri KM, Stern D, Andolfatto P, Wright SI
Evolution 66 (5) 1360-1374 [2012-05-00; online 2012-03-03]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Uncharacterized 4,5-Dihydroxy-2,3-Pentanedione (DPD) Molecules Revealed Through NMR Spectroscopy: Implications for a Greater Signaling Diversity in Bacterial Species
Globisch D, Lowery CA, McCague KC, Janda KD
Angewandte Chemie International Edition 51 (17) 4204-4208 [2012-04-23; online 2012-02-29]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Role of cis-12-Oxo-Phytodienoic Acid in Tomato Embryo Development
Goetz S, Hellwege A, Stenzel I, ..., Wasternack C, Hause B
PLANT PHYSIOLOGY 158 (4) 1715-1727 [2012-04-01; online 2012-02-14]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Preclinical evaluation of a 68Ga-labeled biotin analogue for applications in islet transplantation.
Eriksson O, Carlsson F, Blom E, ..., Korsgren O, Velikyan I
Nucl. Med. Biol. 39 (3) 415-421 [2012-04-00; online 2011-12-01]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast.
García-Martínez J, Ayala G, Pelechano V, ..., Herrero E, Pérez-Ortín JE
Transcription 3 (1) 39-44 [2012-03-30; online 2012-03-30]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Penetration of amphiphilic quantum dots through model and cellular plasma membranes.
Dubavik A, Sezgin E, Lesnyak V, ..., Schwille P, Eychmüller A
ACS Nano 6 (3) 2150-2156 [2012-03-27; online 2012-02-13]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
HER2/HER3 signaling regulates NK cell-mediated cytotoxicity via MHC class I chain-related molecule A and B expression in human breast cancer cell lines.
Okita R, Mougiakakos D, Ando T, ..., Mimura K, Kiessling R
J. Immunol. 188 (5) 2136-2145 [2012-03-01; online 2012-02-01]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Towards a mechanism for histone chaperones
Elsässer SJ, D'Arcy S
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1819 (3-4) 211-221 [2012-03-00; online 2012-03-00]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Imaging the islet graft by positron emission tomography.
Eriksson O, Alavi A
Eur. J. Nucl. Med. Mol. Imaging 39 (3) 533-542 [2012-03-00; online 2011-09-20]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Genome-Based Reconstruction of the Protein Import Machinery in the Secondary Plastid of a Chlorarachniophyte Alga
Hirakawa Y, Burki F, Keeling PJ
Eukaryotic Cell 11 (3) 324-333 [2012-03-00; online 2012-01-20]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Systems medicine and metabolic modelling.
Mardinoglu A, Nielsen J
J. Intern. Med. 271 (2) 142-154 [2012-02-00; online 2011-12-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Select microRNAs are essential for early development in the sea urchin
Song JL, Stoeckius M, Maaskola J, ..., Rajewsky N, Wessel GM
Developmental Biology 362 (1) 104-113 [2012-02-00; online 2012-02-00]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Identifying and Characterizing Alternative Molecular Markers for the Symbiotic and Free-Living Dinoflagellate Genus Symbiodinium
Pochon X, Putnam HM, Burki F, Gates RD
PLoS ONE 7 (1) e29816 [2012-01-04; online 2012-01-04]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades
Friedländer MR, Mackowiak SD, Li N, Chen W, Rajewsky N
Nucleic Acids Res. 40 (1) 37-52 [2012-01-00; online 2011-09-10]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Waves of Retrotransposon Expansion Remodel Genome Organization and CTCF Binding in Multiple Mammalian Lineages
Schmidt D, Schwalie PC, Wilson MD, ..., Flicek P, Odom DT
Cell 148 (1-2) 335-348 [2012-01-00; online 2012-01-00]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
MRT letter: Nanoscopy of protein colocalization in living cells by STED and GSDIM
Lalkens B, Testa I, Willig KI, Hell SW
Microsc. Res. Tech. 75 (1) 1-6 [2012-01-00; online 2012-01-25]
Ilaria Testa SciLifeLab Fellow
DOI Crossref
Inclusion of interactions in mathematical modelling of implant assisted magnetic drug targeting
Cregg PJ, Murphy K, Mardinoglu A
Applied Mathematical Modelling 36 (1) 1-34 [2012-01-00; online 2012-01-00]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Signatures of balancing selection are maintained at disease resistance loci following mating system evolution and a population bottleneck in the genus Capsella
Gos G, Slotte T, Wright SI
BMC Evol Biol BMC Evolutionary Biology 12 (1) 152 [2012-00-00; online 2012-00-00]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Re-evaluating the Green versus Red Signal in Eukaryotes with Secondary Plastid of Red Algal Origin
Burki F, Flegontov P, Oborník M, ..., Lukeš J, Keeling PJ
Genome Biol Evol 4 (6) 626-635 [2012-00-00; online 2012-05-16]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Monitoring Conformational Dynamics with Single-Molecule Fluorescence Energy Transfer: Applications in Nucleosome Remodeling
Deindl S, Zhuang X
- 513 (-) 59-86 [2012-00-00; online 2012-00-00]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Molecular Dynamics Simulations of Voltage-Gated Cation Channels: Insights on Voltage-Sensor Domain Function and Modulation
Delemotte L, Klein ML, Tarek M
Front. Pharmacol. 3 (-) - [2012-00-00; online 2012-00-00]
Lucie Delemotte SciLifeLab Fellow

Year 2011

PubMed DOI Crossref
Striated muscle as implantation site for transplanted pancreatic islets.
Espes D, Eriksson O, Lau J, Carlsson PO
Journal of transplantation 2011 (-) 352043 [2011-12-07; online 2011-12-07]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Decreased defluorination using the novel beta-cell imaging agent [18F]FE-DTBZ-d4 in pigs examined by PET.
Jahan M, Eriksson O, Johnström P, ..., Johansson L, Halldin C
EJNMMI Res 1 (1) 33 [2011-12-05; online 2011-12-05]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
The Conserved Foot Domain of RNA Pol II Associates with Proteins Involved in Transcriptional Initiation and/or Early Elongation
García-López MC, Pelechano V, Mirón-García MC, ..., Pérez-Ortín JE, Navarro F
Genetics 189 (4) 1235-1248 [2011-12-00; online 2011-09-27]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Postpartum depressive symptoms and the BDNF Val66Met functional polymorphism: effect of season of delivery.
Comasco E, Sylvén SM, Papadopoulos FC, ..., Sundström-Poromaa I, Skalkidou A
Arch Womens Ment Health 14 (6) 453-463 [2011-12-00; online 2011-10-14]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Microtubules support a disk-like septin arrangement at the plasma membrane of mammalian cells
Sellin ME, Holmfeldt P, Stenmark S, Gullberg M
MBoC 22 (23) 4588-4601 [2011-12-00; online 2011-12-00]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Fluorescence techniques to study lipid dynamics.
Sezgin E, Schwille P
Cold Spring Harbor Perspectives in Biology 3 (11) a009803 [2011-11-01; online 2011-11-01]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Ligand discovery from a dopamine D3 receptor homology model and crystal structure
Carlsson J, Coleman RG, Setola V, ..., Roth BL, Shoichet BK
Nat Chem Biol 7 (11) 769-778 [2011-11-00; online 2011-09-18]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Formulating a new basis for the treatment against botulinum neurotoxin intoxication: 3,4-Diaminopyridine prodrug design and characterization
Zakhari JS, Kinoyama I, Hixon MS, ..., Globisch D, Janda KD
Bioorganic & Medicinal Chemistry 19 (21) 6203-6209 [2011-11-00; online 2011-11-00]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Systems-Based Analysis of Modified tRNA Bases
Globisch D, Pearson D, Hienzsch A, ..., Sieber SA, Carell T
Angewandte Chemie International Edition 50 (41) 9739-9742 [2011-10-04; online 2011-08-31]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
miR393 and Secondary siRNAs Regulate Expression of the TIR1/AFB2 Auxin Receptor Clade and Auxin-Related Development of Arabidopsis Leaves
Si-Ammour A, Windels D, Arn-Bouldoires E, ..., Meins F, Vazquez F
PLANT PHYSIOLOGY 157 (2) 683-691 [2011-10-01; online 2011-08-09]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Pol III binding in six mammals shows conservation among amino acid isotypes despite divergence among tRNA genes
Kutter C, Brown GD, Gonçalves Â, ..., White RJ, Odom DT
Nat Genet 43 (10) 948-955 [2011-10-00; online 2011-08-28]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Diffraction-unlimited all-optical imaging and writing with a photochromic GFP
Grotjohann T, Testa I, Leutenegger M, ..., Jakobs S, Hell SW
Nature 478 (7368) 204-208 [2011-10-00; online 2011-09-11]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching
Brakemann T, Stiel AC, Weber G, ..., Hell SW, Jakobs S
Nat Biotechnol 29 (10) 942-947 [2011-10-00; online 2011-09-11]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Genomic determinants of protein evolution and polymorphism in Arabidopsis.
Slotte T, Bataillon T, Hansen TT, ..., Wright SI, Schierup MH
Genome Biol Evol 3 (-) 1210-1219 [2011-09-16; online 2011-09-16]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Ecdysteroid receptor from the American lobster Homarus americanus: EcR/RXR isoform cloning and ligand-binding properties.
Tarrant AM, Behrendt L, Stegeman JJ, Verslycke T
Gen. Comp. Endocrinol. 173 (2) 346-355 [2011-09-01; online 2011-06-22]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Deciphering the rules governing assembly order of mammalian septin complexes
Sellin ME, Sandblad L, Stenmark S, Gullberg M
MBoC 22 (17) 3152-3164 [2011-09-00; online 2011-09-00]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
The GC-Rich Mitochondrial and Plastid Genomes of the Green Alga Coccomyxa Give Insight into the Evolution of Organelle DNA Nucleotide Landscape
Smith DR, Burki F, Yamada T, ..., Van Etten JL, Keeling PJ
PLoS ONE 6 (8) e23624 [2011-08-26; online 2011-08-26]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Transition of microbial communities during the adaption to anaerobic digestion of carrot waste.
Garcia SL, Jangid K, Whitman WB, Das KC
Bioresour Technol 102 (15) 7249-7256 [2011-08-00; online 2011-05-06]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Status of GPCR Modeling and Docking as Reflected by Community-wide GPCR Dock 2010 Assessment
Kufareva I, Rueda M, Katritch V, Stevens RC, Abagyan R
Structure 19 (8) 1108-1126 [2011-08-00; online 2011-08-00]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Distribution of adoptively transferred porcine T-lymphoblasts tracked by (18)F-2-fluoro-2-deoxy-D-glucose and position emission tomography.
Eriksson O, Sadeghi A, Carlsson B, ..., Korsgren O, Sundin A
Nucl. Med. Biol. 38 (6) 827-833 [2011-08-00; online 2011-04-21]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Contrasting demographic history and population structure in Capsella rubella and Capsella grandiflora, two closely related species with different mating systems.
St Onge KR, Källman T, Slotte T, Lascoux M, Palmé AE
Mol. Ecol. 20 (16) 3306-3320 [2011-08-00; online 2011-07-21]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
A genomic view of mRNA turnover in yeast
Pérez-Ortín JE, Jordán-Pla A, Pelechano V
Comptes Rendus Biologies 334 (8-9) 647-654 [2011-08-00; online 2011-08-00]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Increased recruitment but impaired function of leukocytes during inflammation in mouse models of type 1 and type 2 diabetes.
Pettersson US, Christoffersson G, Massena S, ..., Henriksnäs J, Phillipson M
PLoS ONE 6 (7) e22480 [2011-07-25; online 2011-07-25]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
5-Hydroxymethylcytosine, the Sixth Base of the Genome
Münzel M, Globisch D, Carell T
Angewandte Chemie International Edition 50 (29) 6460-6468 [2011-07-11; online 2011-06-17]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.
Olerud J, Mokhtari D, Johansson M, ..., Welsh N, Carlsson PO
Diabetes 60 (7) 1946-1954 [2011-07-00; online 2011-05-26]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Modularity of the Bacterial Cell Cycle Enables Independent Spatial and Temporal Control of DNA Replication
Jonas K, Chen YE, Laub MT
Current Biology 21 (13) 1092-1101 [2011-07-00; online 2011-07-00]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Functional consequences of bidirectional promoters
Wei W, Pelechano V, Järvelin AI, Steinmetz LM
Trends in Genetics 27 (7) 267-276 [2011-07-00; online 2011-07-00]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Nanosilver on nanostructured silica: Antibacterial activity and Ag surface area.
Sotiriou GA, Teleki A, Camenzind A, ..., Panke S, Pratsinis SE
Chem Eng J 170 (2-3) 547-554 [2011-06-01; online 2011-06-01]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Nucleus- and nucleomorph-targeted histone proteins in a chlorarachniophyte alga
Hirakawa Y, Burki F, Keeling PJ
Molecular Microbiology 80 (6) 1439-1449 [2011-06-00; online 2011-04-06]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Endolithic chlorophyll d-containing phototrophs.
Behrendt L, Larkum AW, Norman A, ..., Trampe E, Kühl M
ISME J 5 (6) 1072-1076 [2011-06-00; online 2010-12-16]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Assessment of receptor occupancy-over-time of two dopamine transporter inhibitors by [(11)C]CIT and target controlled infusion.
Eriksson O, Långström B, Josephsson R
Ups. J. Med. Sci. 116 (2) 100-106 [2011-05-00; online 2011-03-28]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Discovery and Synthesis of New UV-Induced Intrastrand C(4−8)G and G(8−4)C Photolesions
Münzel M, Szeibert C, Glas AF, Globisch D, Carell T
J. Am. Chem. Soc. 133 (14) 5186-5189 [2011-04-13; online 2011-04-13]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Intermediate states of the Kv1.2 voltage sensor from atomistic molecular dynamics simulations
Delemotte L, Tarek M, Klein ML, Amaral C, Treptow W
Proceedings of the National Academy of Sciences 108 (15) 6109-6114 [2011-04-12; online 2011-03-28]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Hybrid, silica-coated, Janus-like plasmonic-magnetic nanoparticles.
Sotiriou GA, Hirt AM, Lozach PY, ..., Krumeich F, Pratsinis SE
Chem Mater 23 (7) 1985-1992 [2011-04-12; online 2011-04-12]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Genomic-wide methods to evaluate transcription rates in yeast.
García-Martínez J, Pelechano V, Pérez-Ortín JE
Methods in molecular biology (Clifton, N.J.) 734 (-) 25-44 [2011-04-07; online 2011-04-07]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
MAOA genotype, family relations and sexual abuse in relation to adolescent alcohol consumption.
Nilsson KW, Comasco E, Åslund C, ..., Leppert J, Oreland L
Addict Biol 16 (2) 347-355 [2011-04-00; online 2010-08-23]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Parameters of the Protein Energy Landscapes of Several Light-Harvesting Complexes Probed via Spectral Hole Growth Kinetics Measurements
Herascu N, Najafi M, Amunts A, ..., Seibert M, Zazubovich V
J. Phys. Chem. B 115 (12) 2737-2747 [2011-03-31; online 2011-03-31]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Cancer. New epigenetic drivers of cancers.
Elsässer SJ, Allis CD, Lewis PW
Science (New York, N.Y.) 331 (6021) 1145-1146 [2011-03-04; online 2011-03-10]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Intramuscular islet transplantation promotes restored islet vascularity.
Christoffersson G, Carlsson PO, Phillipson M
Islets 3 (2) 69-71 [2011-03-01; online 2011-03-01]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Maltreatment, MAOA, and delinquency: sex differences in gene-environment interaction in a large population-based cohort of adolescents.
Aslund C, Nordquist N, Comasco E, ..., Oreland L, Nilsson KW
Behav. Genet. 41 (2) 262-272 [2011-03-00; online 2010-08-24]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Flux coupling and transcriptional regulation within the metabolic network of the photosynthetic bacterium Synechocystis sp. PCC6803
Montagud A, Zelezniak A, Navarro E, ..., Urchueguía JF, Patil KR
Biotechnology Journal 6 (3) 330-342 [2011-03-00; online 2011-01-11]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
The RACK1 Signaling Scaffold Protein Selectively Interacts with Yersinia pseudotuberculosis Virulence Function
Thorslund SE, Edgren T, Pettersson J, ..., Wolf-Watz H, Fällman M
PLoS ONE 6 (2) e16784 [2011-02-10; online 2011-02-10]
Mikael Sellin SciLifeLab Fellow
DOI Crossref
Theoretical modelling of physiologically stretched vessel in magnetisable stent assisted magnetic drug targeting application
Mardinoglu A, Cregg PJ, Murphy K, Curtin M, Prina-Mello A
Journal of Magnetism and Magnetic Materials 323 (3-4) 324-329 [2011-02-00; online 2011-02-00]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Postpartum depression symptoms: a case-control study on monoaminergic functional polymorphisms and environmental stressors.
Comasco E, Sylvén SM, Papadopoulos FC, ..., Oreland L, Skalkidou A
Psychiatr Genet 21 (1) 19-28 [2011-02-00; online 2010-11-26]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Spatial gradient of protein phosphorylation underlies replicative asymmetry in a bacterium
Chen YE, Tropini C, Jonas K, ..., Huang KC, Laub MT
Proceedings of the National Academy of Sciences 108 (3) 1052-1057 [2011-01-18; online 2010-12-29]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Reduced Efficacy of Natural Selection on Codon Usage Bias in Selfing Arabidopsis and Capsella Species
Qiu S, Zeng K, Slotte T, Wright S, Charlesworth D
Genome Biol Evol 3 (-) 868-880 [2011-01-01; online 2011-08-18]
SciLifeLab Fellow Tanja Slotte
DOI Crossref
Structural dependence of the efficiency of functionalization of silica-coated FeOx magnetic nanoparticles studied by ATR-IR
Vargas A, Shnitko I, Teleki A, ..., Pratsinis SE, Baiker A
Applied Surface Science 257 (7) 2861-2869 [2011-01-00; online 2011-01-00]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
Morphology, structure and magnetic properties of cobalt–nickel films obtained from acidic electrolytes containing glycine
Ergeneman O, Sivaraman KM, Pané S, ..., Baró MD, Nelson BJ
Electrochimica Acta 56 (3) 1399-1408 [2011-01-00; online 2011-01-00]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Anti-apoptotic Bcl-2 fails to form efficient complexes with pro-apoptotic Bak to protect from Celecoxib-induced apoptosis
Rudner J, Elsaesser SJ, Jendrossek V, Huber SM
Biochemical Pharmacology 81 (1) 32-42 [2011-01-00; online 2011-01-00]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
LC-MS based quantification of 2′-ribosylated nucleosides Ar(p) and Gr(p) in tRNA
Pearson D, Hienzsch A, Wagner M, ..., Özden D, Carell T
Chem. Commun. 47 (18) 5196 [2011-00-00; online 2011-00-00]
Daniel Globisch SciLifeLab Fellow

Year 2010

PubMed DOI Crossref
Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates
Globisch D, Münzel M, Müller M, ..., Biel M, Carell T
PLoS ONE 5 (12) e15367 [2010-12-23; online 2010-12-23]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Non-toxic dry-coated nanosilver for plasmonic biosensors.
Sotiriou GA, Sannomiya T, Teleki A, ..., Vörös J, Pratsinis SE
Adv. Funct. Mater. 20 (24) 4250-4257 [2010-12-21; online 2010-12-21]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Efficient Synthesis of 5-Hydroxymethylcytosine Containing DNA
Münzel M, Globisch D, Trindler C, Carell T
Org. Lett. 12 (24) 5671-5673 [2010-12-17; online 2010-12-17]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
A Complete Set of Nascent Transcription Rates for Yeast Genes
Pelechano V, Chávez S, Pérez-Ortín JE
PLoS ONE 5 (11) e15442 [2010-11-16; online 2010-11-16]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
A Novel Synthetic Route for the Anti-HIV Drug MC-1220 and its Analogues
Loksha YM, Globisch D, Loddo R, ..., La Colla P, Pedersen EB
ChemMedChem 5 (11) 1847-1849 [2010-11-08; online 2010-08-16]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Heat shock transcription factor 1 localizes to sex chromatin during meiotic repression.
Akerfelt M, Vihervaara A, Laiho A, ..., Sistonen L, Henriksson E
J Biol Chem 285 (45) 34469-34476 [2010-11-05; online 2010-08-27]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Incorporation of Mg and Ca into nanostructured Fe2O3 improves Fe solubility in dilute acid and sensory characteristics in foods.
Hilty FM, Knijnenburg JT, Teleki A, ..., Pratsinis SE, Zimmermann MB
J Food Sci 76 (1) N2-10 [2010-11-04; online 2010-11-04]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
Synthesis of novel analogues of zanamivir as neuraminidase inhibitors
Xiong RS, Zhao QJ, Zhu HH, ..., Wei YB, Shen JS
Chinese Chemical Letters 21 (11) 1338-1341 [2010-11-00; online 2010-11-00]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Effect of Sensor Domain Mutations on the Properties of Voltage-Gated Ion Channels: Molecular Dynamics Studies of the Potassium Channel Kv1.2
Delemotte L, Treptow W, Klein ML, Tarek M
Biophysical Journal 99 (9) L72-L74 [2010-11-00; online 2010-11-00]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Far-Field Autofluorescence Nanoscopy
Bierwagen J, Testa I, Fölling J, ..., Eggeling C, Hell SW
Nano Lett. 10 (10) 4249-4252 [2010-10-13; online 2010-10-13]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Semiconductor gas sensors: dry synthesis and application.
Tricoli A, Righettoni M, Teleki A
Angew. Chem. Int. Ed. Engl. 49 (42) 7632-7659 [2010-10-11; online 2010-08-19]
Alexandra Teleki SciLifeLab Fellow
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Neuroticism-related personality traits are related to symptom severity in patients with premenstrual dysphoric disorder and to the serotonin transporter gene-linked polymorphism 5-HTTPLPR.
Gingnell M, Comasco E, Oreland L, Fredrikson M, Sundström-Poromaa I
Arch Womens Ment Health 13 (5) 417-423 [2010-10-00; online 2010-05-04]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Multicolor Fluorescence Nanoscopy in Fixed and Living Cells by Exciting Conventional Fluorophores with a Single Wavelength
Testa I, Wurm CA, Medda R, ..., Hell SW, Eggeling C
Biophysical Journal 99 (8) 2686-2694 [2010-10-00; online 2010-10-00]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Clinical and experimental pancreatic islet transplantation to striated muscle: establishment of a vascular system similar to that in native islets.
Christoffersson G, Henriksnäs J, Johansson L, ..., Carlsson PO, Phillipson M
Diabetes 59 (10) 2569-2578 [2010-10-00; online 2010-07-22]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Light entrained rhythmic gene expression in the sea anemone Nematostella vectensis: the evolution of the animal circadian clock.
Reitzel AM, Behrendt L, Tarrant AM
PLoS ONE 5 (9) e12805 [2010-09-21; online 2010-09-21]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils.
Massena S, Christoffersson G, Hjertström E, ..., Li JP, Phillipson M
Blood 116 (11) 1924-1931 [2010-09-16; online 2010-06-08]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
Lewis PW, Elsaesser SJ, Noh KM, Stadler SC, Allis CD
Proceedings of the National Academy of Sciences 107 (32) 14075-14080 [2010-08-10; online 2010-07-22]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Genome-Wide Evidence for Efficient Positive and Purifying Selection in Capsella grandiflora, a Plant Species with a Large Effective Population Size
Slotte T, Foxe JP, Hazzouri KM, Wright SI
Molecular Biology and Evolution 27 (8) 1813-1821 [2010-08-01; online 2010-03-01]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Why do adolescents drink? Motivational patterns related to alcohol consumption and alcohol-related problems.
Comasco E, Berglund K, Oreland L, Nilsson KW
Subst Use Misuse 45 (10) 1589-1604 [2010-08-00; online 2010-07-02]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors
Rodríguez-Gil A, García-Martínez J, Pelechano V, ..., Pérez-Ortín JE, Chávez S
Nucleic Acids Res. 38 (14) 4651-4664 [2010-08-00; online 2010-04-10]
SciLifeLab Fellow Vicente Pelechano
DOI Crossref
Many particle magnetic dipole–dipole and hydrodynamic interactions in magnetizable stent assisted magnetic drug targeting
Cregg PJ, Murphy K, Mardinoglu A, Prina-Mello A
Journal of Magnetism and Magnetic Materials 322 (15) 2087-2094 [2010-08-00; online 2010-08-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Impacts of added dissolved organic carbon on boreal freshwater pelagic metabolism and food webs in mesocosm experiments
Kankaala P, Peura S, Nykänen H, ..., Tiirola M, Jones RI
Fund. App. Lim. 177 (3) 161-176 [2010-07-09; online 2010-07-09]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Upregulated Op18/stathmin activity causes chromosomal instability through a mechanism that evades the spindle assembly checkpoint
Holmfeldt P, Sellin ME, Gullberg M
Experimental Cell Research 316 (12) 2017-2026 [2010-07-00; online 2010-07-00]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Quantification of the Sixth DNA Base Hydroxymethylcytosine in the Brain
Münzel M, Globisch D, Brückl T, ..., Biel M, Carell T
Angewandte Chemie International Edition 49 (31) 5375-5377 [2010-06-25; online 2010-06-25]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Induction of cytochrome P450 1 genes and stress response genes in developing zebrafish exposed to ultraviolet radiation.
Behrendt L, Jönsson ME, Goldstone JV, Stegeman JJ
Aquat Toxicol 98 (1) 74-82 [2010-06-01; online 2010-02-04]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Local release of highly loaded antibodies from functionalized nanoporous support for cancer immunotherapy.
Lei C, Liu P, Chen B, ..., Liu J, Hellstrom KE
Journal of the American Chemical Society 132 (20) 6906-6907 [2010-05-26; online 2010-05-04]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding
Schmidt D, Wilson MD, Ballester B, ..., Flicek P, Odom DT
Science 328 (5981) 1036-1040 [2010-05-21; online 2010-04-08]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Structure-Based Discovery of A2A Adenosine Receptor Ligands
Carlsson J, Yoo L, Gao ZG, ..., Shoichet BK, Jacobson KA
J. Med. Chem. 53 (9) 3748-3755 [2010-05-13; online 2010-05-13]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression
Git A, Dvinge H, Salmon-Divon M, ..., Bertone P, Caldas C
RNA 16 (5) 991-1006 [2010-05-01; online 2010-04-01]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Understanding biological dynamics: following cells and molecules to track functions and mechanisms
Palamidessi A, Testa I, Frittoli E, ..., Scita G, Faretta M
Eur Biophys J 39 (6) 947-957 [2010-05-00; online 2009-05-20]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Iron from nanocompounds containing iron and zinc is highly bioavailable in rats without tissue accumulation.
Hilty FM, Arnold M, Hilbe M, ..., Langhans W, Zimmermann MB
Nat Nanotechnol 5 (5) 374-380 [2010-05-00; online 2010-04-25]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Continuous surface functionalization of flame-made TiO2 nanoparticles.
Teleki A, Bjelobrk N, Pratsinis SE
Langmuir 26 (8) 5815-5822 [2010-04-20; online 2010-03-03]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Metabolic Network Topology Reveals Transcriptional Regulatory Signatures of Type 2 Diabetes
Zelezniak A, Pers TH, Soares S, Patti ME, Patil KR
PLoS Comput Biol 6 (4) e1000729 [2010-04-01; online 2010-04-01]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
New functions for an old variant: no substitute for histone H3.3
Elsaesser SJ, Goldberg AD, Allis CD
Current Opinion in Genetics & Development 20 (2) 110-117 [2010-04-00; online 2010-04-00]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
In vivo and in vitro characterization of [18F]-FE-(+)-DTBZ as a tracer for beta-cell mass.
Eriksson O, Jahan M, Johnström P, ..., Halldin C, Johansson L
Nucl. Med. Biol. 37 (3) 357-363 [2010-04-00; online 2010-01-15]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
There is a steady-state transcriptome in exponentially growing yeast cells
Pelechano V, Pérez-Ortín JE
Yeast 27 (7) 413-422 [2010-03-17; online 2010-03-17]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation
Chao LH, Pellicena P, Deindl S, ..., Schulman H, Kuriyan J
Nat Struct Mol Biol 17 (3) 264-272 [2010-03-00; online 2010-02-07]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions
Goldberg AD, Banaszynski LA, Noh KM, ..., Zheng D, Allis CD
Cell 140 (5) 678-691 [2010-03-00; online 2010-03-00]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Unconventional Ubiquitin Recognition by the Ubiquitin-Binding Motif within the Y Family DNA Polymerases ι and Rev1
Bomar MG, D'Souza S, Bienko M, ..., Walker GC, Zhou P
Molecular Cell 37 (3) 408-417 [2010-02-00; online 2010-02-00]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
The clock gene PER2 and sleep problems: association with alcohol consumption among Swedish adolescents.
Comasco E, Nordquist N, Göktürk C, ..., Oreland L, Nilsson KW
Ups. J. Med. Sci. 115 (1) 41-48 [2010-02-00; online 2010-03-02]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination
Bienko M, Green CM, Sabbioneda S, ..., Lehmann AR, Dikic I
Molecular Cell 37 (3) 396-407 [2010-02-00; online 2010-02-00]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Complex regulatory network encompassing the Csr, c-di-GMP and motility systems of Salmonella Typhimurium.
Jonas K, Edwards AN, Ahmad I, ..., Römling U, Melefors O
Environ. Microbiol. 12 (2) 524-540 [2010-02-00; online 2009-11-17]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Structure Determination and Improved Model of Plant Photosystem I
Amunts A, Toporik H, Borovikova A, Nelson N
J. Biol. Chem. 285 (5) 3478-3486 [2010-01-29; online 2009-11-18]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Differential effects of anti-apoptotic Bcl-2 family members Mcl-1, Bcl-2, and Bcl-xL on Celecoxib-induced apoptosis
Rudner J, Elsaesser SJ, Müller AC, Belka C, Jendrossek V
Biochemical Pharmacology 79 (1) 10-20 [2010-01-00; online 2010-01-00]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
Novel and Practical Synthesis of Candesartan Cilexetil
Shen J, Mao Y, Xiong R, ..., Li H, Shen J
HETEROCYCLES 81 (6) 1503 [2010-00-00; online 2010-00-00]
Ruisheng Xiong SciLifeLab Fellow
DOI Crossref
Improved Total Synthesis of Racemic Rutamarin
Jiang X, Sun H, Xiong R, ..., Jiang H, Shen J
HETEROCYCLES 81 (7) 1697 [2010-00-00; online 2010-00-00]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Evolution of Rhizaria: new insights from phylogenomic analysis of uncultivated protists
Burki F, Kudryavtsev A, Matz MV, ..., Keeling PJ, Pawlowski J
BMC Evol Biol BMC Evolutionary Biology 10 (1) 377 [2010-00-00; online 2010-00-00]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Deciphering the porcine intestinal microRNA transcriptome
Sharbati S, Friedlander MR, Sharbati J, ..., Rajewsky N, Einspanier R
BMC Genomics 11 (1) 275 [2010-00-00; online 2010-00-00]
Marc Friedländer SciLifeLab Fellow

Year 2009

PubMed DOI Crossref
Transcription factor AP2 beta involved in severe female alcoholism.
Nordquist N, Göktürk C, Comasco E, ..., Oreland L, Hallman J
Brain Res 1305 Suppl (-) S20-S26 [2009-12-11; online 2009-09-22]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Stability of an autoinhibitory interface in the structure of the tyrosine kinase ZAP-70 impacts T cell receptor response.
Deindl S, Kadlecek TA, Cao X, Kuriyan J, Weiss A
Proc. Natl. Acad. Sci. U.S.A. 106 (49) 20699-20704 [2009-12-08; online 2009-11-17]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Positron emission tomography in clinical islet transplantation.
Eriksson O, Eich T, Sundin A, ..., Korsgren O, Lundgren T
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 9 (12) 2816-2824 [2009-12-00; online 2009-10-21]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Development and optimization of iron- and zinc-containing nanostructured powders for nutritional applications
Hilty FM, Teleki A, Krumeich F, ..., Pratsinis SE, Zimmermann MB
Nanotechnology 20 (47) 475101 [2009-11-25; online 2009-10-29]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish.
Jönsson ME, Franks DG, Woodin BR, ..., Hahn ME, Stegeman JJ
Chem. Biol. Interact. 181 (3) 447-454 [2009-10-30; online 2009-07-15]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
AIR: A batch-oriented web program package for construction of supermatrices ready for phylogenomic analyses.
Kumar S, Skjaeveland A, Orr RJ, ..., Botnen A, Shalchian-Tabrizi K
BMC Bioinformatics 10 (-) 357 [2009-10-28; online 2009-10-28]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Predominant regulators of tubulin monomer-polymer partitioning and their implication for cell polarization.
Holmfeldt P, Sellin ME, Gullberg M
Cell. Mol. Life Sci. 66 (20) 3263-3276 [2009-10-00; online 2009-07-08]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Large-scale sorting of C. elegans embryos reveals the dynamics of small RNA expression.
Stoeckius M, Maaskola J, Colombo T, ..., Piano F, Rajewsky N
Nat. Methods 6 (10) 745-751 [2009-10-00; online 2009-09-06]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Parallel isotope-based quantification of modified tRNA nucleosides.
Brückl T, Globisch D, Wagner M, Müller M, Carell T
Angew. Chem. Int. Ed. Engl. 48 (42) 7932-7934 [2009-09-12; online 2009-09-12]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
The transcription factor TFAP2B is associated with insulin resistance and adiposity in healthy adolescents.
Nordquist N, Göktürk C, Comasco E, ..., Oreland L, Harro J
Obesity (Silver Spring) 17 (9) 1762-1767 [2009-09-00; online 2009-03-26]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Splicing variation at a FLOWERING LOCUS C homeolog is associated with flowering time variation in the tetraploid Capsella bursa-pastoris.
Slotte T, Huang HR, Holm K, ..., Lagercrantz U, Lascoux M
Genetics 183 (1) 337-345 [2009-09-00; online 2009-07-06]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Impact of the interaction between the 5HTTLPR polymorphism and maltreatment on adolescent depression. A population-based study.
Aslund C, Leppert J, Comasco E, ..., Oreland L, Nilsson KW
Behav. Genet. 39 (5) 524-531 [2009-09-00; online 2009-07-07]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Adolescent alcohol consumption: biomarkers PEth and FAEE in relation to interview and questionnaire data.
Comasco E, Nordquist N, Leppert J, ..., Alling C, Nilsson KW
J Stud Alcohol Drugs 70 (5) 797-804 [2009-09-00; online 2009-09-10]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
The Escherichia coli CsrB and CsrC small RNAs are strongly induced during growth in nutrient-poor medium.
Jonas K, Melefors O
FEMS Microbiol. Lett. 297 (1) 80-86 [2009-08-00; online 2009-05-21]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Regulon-specific control of transcription elongation across the yeast genome.
Pelechano V, Jimeno-González S, Rodríguez-Gil A, ..., Pérez-Ortín JE, Chávez S
PLoS Genet 5 (8) e1000614 [2009-08-00; online 2009-08-21]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Absolute hydration entropies of alkali metal ions from molecular dynamics simulations.
Carlsson J, Aqvist J
J. Phys. Chem. B 113 (30) 10255-10260 [2009-07-30; online 2009-07-08]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Large-scale phylogenomic analyses reveal that two enigmatic protist lineages, telonemia and centroheliozoa, are related to photosynthetic chromalveolates.
Burki F, Inagaki Y, Bråte J, ..., Pawlowski J, Shalchian-Tabrizi K
Genome Biol Evol 1 (-) 231-238 [2009-07-27; online 2009-07-27]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
High-resolution profiling and discovery of planarian small RNAs.
Friedländer MR, Adamidi C, Han T, ..., Kim JK, Rajewsky N
Proc. Natl. Acad. Sci. U.S.A. 106 (28) 11546-11551 [2009-07-14; online 2009-06-29]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Interaction of gold nanoparticles with mitochondria.
Karataş OF, Sezgin E, Aydin O, Culha M
Colloids Surf B Biointerfaces 71 (2) 315-318 [2009-07-01; online 2009-03-06]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment.
Jura N, Endres NF, Engel K, ..., Zhang X, Kuriyan J
Cell 137 (7) 1293-1307 [2009-06-26; online 2009-07-01]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
Hermetically Coated Superparamagnetic Fe2O3Particles with SiO2Nanofilms
Teleki A, Suter M, Kidambi PR, ..., Nelson BJ, Pratsinis SE
Chem Mater 21 (10) 2094-2100 [2009-05-26; online 2009-05-26]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Blue nano titania made in diffusion flames.
Teleki A, Pratsinis SE
Phys Chem Chem Phys 11 (19) 3742-3747 [2009-05-21; online 2009-03-02]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Plant photosystem I design in the light of evolution.
Amunts A, Nelson N
Structure 17 (5) 637-650 [2009-05-13; online 2009-05-19]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash.
Petersson J, Carlström M, Schreiber O, ..., Lundberg JO, Holm L
Free Radic. Biol. Med. 46 (8) 1068-1075 [2009-04-15; online 2009-01-21]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Untangling the phylogeny of amoeboid protists.
Pawlowski J, Burki F
J. Eukaryot. Microbiol. 56 (1) 16-25 [2009-04-02; online 2009-04-02]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Active-site motions and polarity enhance catalytic turnover of hydrated subtilisin dissolved in organic solvents.
Hudson EP, Eppler RK, Beaudoin JM, ..., Reimer JA, Clark DS
Journal of the American Chemical Society 131 (12) 4294-4300 [2009-04-01; online 2009-03-26]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Regulation of c-di-GMP metabolism in biofilms.
Jonas K, Melefors O, Römling U
Future Microbiol 4 (3) 341-358 [2009-04-00; online 2009-03-31]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Personality and the serotonin transporter gene: Associations in a longitudinal population-based study.
Harro J, Merenäkk L, Nordquist N, ..., Comasco E, Oreland L
Biol Psychol 81 (1) 9-13 [2009-04-00; online 2009-05-14]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Recent speciation of Capsella rubella from Capsella grandiflora, associated with loss of self-incompatibility and an extreme bottleneck.
Guo YL, Bechsgaard JS, Slotte T, ..., Weigel D, Schierup MH
Proc. Natl. Acad. Sci. U.S.A. 106 (13) 5246-5251 [2009-03-31; online 2009-03-23]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Recent speciation associated with the evolution of selfing in Capsella.
Foxe JP, Slotte T, Stahl EA, ..., Hurka H, Wright SI
Proc. Natl. Acad. Sci. U.S.A. 106 (13) 5241-5245 [2009-03-31; online 2009-02-19]
SciLifeLab Fellow Tanja Slotte
DOI Crossref
Synthesis and anti‐HIV‐1 evaluation of 1,5‐disubstituted pyrimidine‐2,4‐diones
Loksha YM, Globisch D, Pedersen EB, ..., Collu G, Loddo R
J. Heterocyclic Chem. 45 (-) 1161-1166 [2009-03-13; online 2009-03-13]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
The structure, regulation, and function of ZAP-70.
Au-Yeung BB, Deindl S, Hsu LY, ..., Kuriyan J, Weiss A
Immunol. Rev. 228 (1) 41-57 [2009-03-00; online 2009-03-18]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 assembles into a nine-subunit oligomer with potential To inhibit Toll-like receptor signaling.
Brännström K, Sellin ME, Holmfeldt P, Brattsand M, Gullberg M
Infect. Immun. 77 (3) 1144-1154 [2009-03-00; online 2009-01-05]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization.
Sabbioneda S, Green CM, Bienko M, ..., Dikic I, Lehmann AR
Proc. Natl. Acad. Sci. U.S.A. 106 (8) E20; author reply E21 [2009-02-24; online 2009-02-26]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Evolutionary position of breviate amoebae and the primary eukaryote divergence.
Minge MA, Silberman JD, Orr RJ, ..., Skjaeveland A, Jakobsen KS
Proceedings of the Royal Society B: Biological Sciences 276 (1657) 597-604 [2009-02-22; online 2008-11-14]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Charges for Large Scale Binding Free Energy Calculations with the Linear Interaction Energy Method.
Wallin G, Nervall M, Carlsson J, Åqvist J
J. Chem. Theory Comput. 5 (2) 380-395 [2009-02-10; online 2009-02-10]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Cytochrome P450 1D1: a novel CYP1A-related gene that is not transcriptionally activated by PCB126 or TCDD.
Goldstone JV, Jönsson ME, Behrendt L, ..., Nelson DR, Stegeman JJ
Arch. Biochem. Biophys. 482 (1-2) 7-16 [2009-02-00; online 2008-12-10]
Lars Behrendt SciLifeLab Fellow
DOI Crossref
Role of Gas−Aerosol Mixing during in Situ Coating of Flame-Made Titania Particles
Teleki A, Buesser B, Heine MC, ..., Akhtar MK, Pratsinis SE
Ind. Eng. Chem. Res. 48 (1) 85-92 [2009-01-07; online 2009-01-07]
Alexandra Teleki SciLifeLab Fellow

Year 2008

PubMed DOI Crossref
Picosecond fluorescence of intact and dissolved PSI-LHCI crystals.
van Oort B, Amunts A, Borst JW, ..., van Amerongen H, Croce R
Biophys. J. 95 (12) 5851-5861 [2008-12-15; online 2008-10-17]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Human Wrnip1 is localized in replication factories in a ubiquitin-binding zinc finger-dependent manner.
Crosetto N, Bienko M, Hibbert RG, ..., Sixma TK, Dikic I
J. Biol. Chem. 283 (50) 35173-35185 [2008-12-12; online 2008-10-07]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Nanoscale separation of molecular species based on their rotational mobility.
Testa I, Schönle A, von Middendorff C, ..., Hell SW, Egner A
Opt Express 16 (25) 21093-21104 [2008-12-08; online 2008-12-10]
Ilaria Testa SciLifeLab Fellow
DOI Crossref
Calculation of nanoparticle capture efficiency in magnetic drug targeting
Cregg PJ, Murphy K, Mardinoglu A
Journal of Magnetism and Magnetic Materials 320 (23) 3272-3275 [2008-12-00; online 2008-12-00]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
A human snoRNA with microRNA-like functions.
Ender C, Krek A, Friedländer MR, ..., Rajewsky N, Meister G
Mol. Cell 32 (4) 519-528 [2008-11-21; online 2008-11-26]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
In situ coating of flame-made TiO2 particles with nanothin SiO2 films.
Teleki A, Heine MC, Krumeich F, Akhtar MK, Pratsinis SE
Langmuir 24 (21) 12553-12558 [2008-11-04; online 2008-10-11]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Sortase-mediated assembly and surface topology of adhesive pneumococcal pili.
Fälker S, Nelson AL, Morfeldt E, ..., Normark S, Henriques-Normark B
Mol. Microbiol. 70 (3) 595-607 [2008-11-00; online 2008-09-17]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Importance of Bak for celecoxib-induced apoptosis.
Müller AC, Handrick R, Elsaesser SJ, ..., Belka C, Jendrossek V
Biochem. Pharmacol. 76 (9) 1082-1096 [2008-10-30; online 2008-08-19]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
miRNA, siRNA, piRNA: Knowns of the unknown.
Kutter C, Svoboda P
RNA Biol 5 (4) 181-188 [2008-10-16; online 2008-10-16]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Biocatalyst activity in nonaqueous environments correlates with centisecond-range protein motions.
Eppler RK, Hudson EP, Chase SD, ..., Reimer JA, Clark DS
Proc. Natl. Acad. Sci. U.S.A. 105 (41) 15672-15677 [2008-10-14; online 2008-10-07]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
The RNA binding protein CsrA controls cyclic di-GMP metabolism by directly regulating the expression of GGDEF proteins.
Jonas K, Edwards AN, Simm R, ..., Römling U, Melefors O
Mol. Microbiol. 70 (1) 236-257 [2008-10-00; online 2008-08-18]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
A new FRAP/FRAPa method for three-dimensional diffusion measurements based on multiphoton excitation microscopy.
Mazza D, Braeckmans K, Cella F, ..., De Smedt SS, Diaspro A
Biophys. J. 95 (7) 3457-3469 [2008-10-00; online 2008-07-11]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Regioselective synthesis of 4azido-Neu2en5,7Ac(2)1Me and its intramolecular transformation to 4azido-Neu2en5,9Ac(2)1Me.
Zhao Q, Lou Y, Xiong R, Li H, Shen J
Carbohydr Res 343 (14) 2459-2462 [2008-09-22; online 2008-06-20]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Photoactivation of pa-GFP in 3D: optical tools for spatial confinement.
Testa I, Garrè M, Parazzoli D, ..., Faretta M, Diaspro A
Eur Biophys J 37 (7) 1219-1227 [2008-09-00; online 2008-04-01]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Phylogenomics reveals a new 'megagroup' including most photosynthetic eukaryotes.
Burki F, Shalchian-Tabrizi K, Pawlowski J
Biol. Lett. 4 (4) 366-369 [2008-08-23; online 2008-06-05]
Fabien Burki SciLifeLab Fellow
DOI Crossref
Non-Linear Microscopy
Mazza D, Bianchini P, Caorsi V, ..., Vicidomini G, Diaspro A
Springer [book chapter] (-) 47-69 [2008-08-13]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Promoter ChIP-chip analysis in mouse testis reveals Y chromosome occupancy by HSF2.
Akerfelt M, Henriksson E, Laiho A, ..., Kotaja N, Sistonen L
Proc. Natl. Acad. Sci. U.S.A. 105 (32) 11224-11229 [2008-08-12; online 2008-08-05]
Anniina Vihervaara SciLifeLab Fellow
DOI Crossref
Ferroelectric WO3Nanoparticles for Acetone Selective Detection
Wang L, Teleki A, Pratsinis SE, Gouma PI
Chem Mater 20 (15) 4794-4796 [2008-08-00; online 2008-08-00]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration.
Palamidessi A, Frittoli E, Garré M, ..., Scita G, Di Fiore PP
Cell 134 (1) 135-147 [2008-07-11; online 2008-07-11]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Polyploid speciation did not confer instant reproductive isolation in Capsella (Brassicaceae).
Slotte T, Huang H, Lascoux M, Ceplitis A
Mol. Biol. Evol. 25 (7) 1472-1481 [2008-07-00; online 2008-04-15]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Global regulation of the interphase microtubule system by abundantly expressed Op18/stathmin.
Sellin ME, Holmfeldt P, Stenmark S, Gullberg M
Mol. Biol. Cell 19 (7) 2897-2906 [2008-07-00; online 2008-04-23]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
A computerized infusion pump for control of tissue tracer concentration during positron emission tomography in vivo pharmacokinetic/pharmacodynamic measurements.
Eriksson O, Wallberg A, Syvänen S, ..., Långström B, Bergström M
BMC medical physics 8 (-) 2 [2008-05-30; online 2008-05-30]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Predicting binding modes from free energy calculations.
Nervall M, Hanspers P, Carlsson J, Boukharta L, Aqvist J
J. Med. Chem. 51 (9) 2657-2667 [2008-05-08; online 2008-04-12]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Modeling membranes under a transmembrane potential.
Delemotte L, Dehez F, Treptow W, Tarek M
J. Phys. Chem. B 112 (18) 5547-5550 [2008-05-08; online 2008-04-16]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Combining docking, molecular dynamics and the linear interaction energy method to predict binding modes and affinities for non-nucleoside inhibitors to HIV-1 reverse transcriptase.
Carlsson J, Boukharta L, Aqvist J
J. Med. Chem. 51 (9) 2648-2656 [2008-05-08; online 2008-04-12]
Jens Carlsson SciLifeLab Fellow
DOI Crossref
Synthesis andin vitro evaluation of18F-β-carboline alkaloids as PET ligands
Blom E, Karimi F, Eriksson O, Hall H, Långström B
J Label Compd Radiopharm 51 (6) 277-282 [2008-05-00; online 2008-00-00]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Stability ofHoogsteen-Type Triplexes – Electrostatic Attraction between Duplex Backbone and Triplex-Forming Oligonucleotide (TFO) Using an Intercalating Conjugate
Globisch D, Bomholt N, Filichev VV, Pedersen EB
HCA 91 (5) 805-818 [2008-05-00; online 2008-05-00]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Op18/Stathmin counteracts the activity of overexpressed tubulin-disrupting proteins in a human leukemia cell line.
Sellin ME, Holmfeldt P, Stenmark S, Gullberg M
Experimental Cell Research 314 (6) 1367-1377 [2008-04-01; online 2008-01-05]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Spatial control of pa-GFP photoactivation in living cells.
Testa I, Parazzoli D, Barozzi S, ..., Faretta M, Diaspro A
J Microsc 230 (Pt 1) 48-60 [2008-04-00; online 2008-04-05]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Positron emission tomography and target-controlled infusion for precise modulation of brain drug concentration.
Eriksson O, Josephsson R, Långstrom B, Bergström M
Nuclear medicine and biology 35 (3) 299-303 [2008-04-00; online 2008-03-22]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Discovering microRNAs from deep sequencing data using miRDeep.
Friedländer MR, Chen W, Adamidi C, ..., Knespel S, Rajewsky N
Nat. Biotechnol. 26 (4) 407-415 [2008-04-00; online 2008-04-09]
Marc Friedländer SciLifeLab Fellow
DOI Crossref
Flame-made Nb- and Cu-doped TiO2 sensors for CO and ethanol
TELEKI A, BJELOBRK N, PRATSINIS S
Sensors and Actuators B: Chemical 130 (1) 449-457 [2008-03-14; online 2008-03-14]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
In situ observation of protein phosphorylation by high-resolution NMR spectroscopy.
Selenko P, Frueh DP, Elsaesser SJ, ..., Gygi SP, Wagner G
Nat. Struct. Mol. Biol. 15 (3) 321-329 [2008-03-00; online 2008-02-24]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Functional organization of a plant Photosystem I: evolution of a highly efficient photochemical machine.
Amunts A, Nelson N
Plant Physiol. Biochem. 46 (3) 228-237 [2008-03-00; online 2008-01-03]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significance.
Guo C, Tang TS, Bienko M, Dikic I, Friedberg EC
J. Biol. Chem. 283 (8) 4658-4664 [2008-02-22; online 2007-12-26]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
The transcriptional inhibitor thiolutin blocks mRNA degradation in yeast.
Pelechano V, Pérez-Ortín JE
Yeast 25 (2) 85-92 [2008-02-00; online 2007-10-05]
SciLifeLab Fellow Vicente Pelechano
DOI Crossref
Nanostructure Evolution: From Aggregated to Spherical SiO2 Particles Made in Diffusion Flames
Camenzind A, Schulz H, Teleki A, ..., Narayanan T, Pratsinis SE
Eur. J. Inorg. Chem. 2008 (6) 911-918 [2008-02-00; online 2008-02-00]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
Distinguishing between aggregates and agglomerates of flame-made TiO2 by high-pressure dispersion
Teleki A, Wengeler R, Wengeler L, Nirschl H, Pratsinis SE
Powder Technology 181 (3) 292-300 [2008-02-00; online 2008-02-00]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
The quality of SiO2-coatings on flame-made TiO2-based nanoparticles
Teleki A, Akhtar MK, Pratsinis SE
J. Mater. Chem. 18 (30) 3547 [2008-00-00; online 2008-00-00]
Alexandra Teleki SciLifeLab Fellow

Year 2007

PubMed DOI Crossref
The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 is a membrane-binding protein that lacks the proposed microtubule-regulatory activity.
Holmfeldt P, Brännström K, Sellin ME, ..., Carlsson SR, Gullberg M
Molecular and biochemical parasitology 156 (2) 225-234 [2007-12-00; online 2007-08-25]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Improving the Accuracy of the Linear Interaction Energy Method for Solvation Free Energies.
Almlöf M, Carlsson J, Åqvist J
J. Chem. Theory Comput. 3 (6) 2162-2175 [2007-11-00; online 2007-11-01]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Positron emission tomography: a real-time tool to quantify early islet engraftment in a preclinical large animal model.
Eich T, Eriksson O, Sundin A, ..., Korsgren O, Lundgren T
Transplantation 84 (7) 893-898 [2007-10-15; online 2007-11-07]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Blue-light (488nm)-irradiation-induced photoactivation of the photoactivatable green fluorescent protein
Testa I, Mazza D, Barozzi S, Faretta M, Diaspro A
Appl. Phys. Lett. 91 (13) 133902 [2007-09-24; online 2007-09-24]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Differential expression of genes important for adaptation in Capsella bursa-pastoris (Brassicaceae).
Slotte T, Holm K, McIntyre LM, Lagercrantz U, Lascoux M
PLANT PHYSIOLOGY 145 (1) 160-173 [2007-09-00; online 2007-07-13]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Phylogenomics reshuffles the eukaryotic supergroups.
Burki F, Shalchian-Tabrizi K, Minge M, ..., Jakobsen KS, Pawlowski J
PLoS ONE 2 (8) e790 [2007-08-29; online 2007-08-29]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
MicroRNA-mediated regulation of stomatal development in Arabidopsis.
Kutter C, Schöb H, Stadler M, Meins F, Si-Ammour A
Plant Cell 19 (8) 2417-2429 [2007-08-00; online 2007-08-17]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Roles of curli, cellulose and BapA in Salmonella biofilm morphology studied by atomic force microscopy.
Jonas K, Tomenius H, Kader A, ..., Belova LM, Melefors O
BMC Microbiol. 7 (-) 70 [2007-07-24; online 2007-07-24]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis.
Henriksson LM, Unge T, Carlsson J, ..., Mowbray SL, Jones TA
J. Biol. Chem. 282 (27) 19905-19916 [2007-07-06; online 2007-05-09]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Visualization of early engraftment in clinical islet transplantation by positron-emission tomography.
Eich T, Eriksson O, Lundgren T, Nordic Network for Clinical Islet Transplantation
N. Engl. J. Med. 356 (26) 2754-2755 [2007-06-28; online 2007-06-29]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Structural basis for the inhibition of tyrosine kinase activity of ZAP-70.
Deindl S, Kadlecek TA, Brdicka T, ..., Weiss A, Kuriyan J
Cell 129 (4) 735-746 [2007-05-18; online 2007-05-22]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
The structure of a plant photosystem I supercomplex at 3.4 A resolution.
Amunts A, Drory O, Nelson N
Nature 447 (7140) 58-63 [2007-05-03; online 2007-05-04]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Active site of epoxide hydrolases revisited: a noncanonical residue in potato StEH1 promotes both formation and breakdown of the alkylenzyme intermediate.
Thomaeus A, Carlsson J, Aqvist J, Widersten M
Biochemistry 46 (9) 2466-2479 [2007-03-06; online 2007-02-07]
Jens Carlsson SciLifeLab Fellow

Year 2006

PubMed DOI Crossref
Calculations of solute and solvent entropies from molecular dynamics simulations.
Carlsson J, Aqvist J
Phys Chem Chem Phys 8 (46) 5385-5395 [2006-12-14; online 2006-09-08]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
pH-dependent activation of the BarA-UvrY two-component system in Escherichia coli.
Mondragón V, Franco B, Jonas K, ..., Melefors O, Georgellis D
J. Bacteriol. 188 (23) 8303-8306 [2006-12-00; online 2006-09-15]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damage.
Guo C, Tang TS, Bienko M, ..., Dikic I, Friedberg EC
Molecular and Cellular Biology 26 (23) 8892-8900 [2006-12-00; online 2006-09-18]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Ubiquitin hubs in oncogenic networks.
Crosetto N, Bienko M, Dikic I
Molecular cancer research : MCR 4 (12) 899-904 [2006-12-00; online 2006-12-26]
Magda Bienko SciLifeLab Fellow
DOI Crossref
Sensing of organic vapors by flame-made TiO2 nanoparticles
Teleki A, Pratsinis SE, Kalyanasundaram K, Gouma PI
Sensors and Actuators B: Chemical 119 (2) 683-690 [2006-12-00; online 2006-12-00]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Intrageneric phylogeny of Capsella (Brassicaceae) and the origin of the tetraploid C. bursa-pastoris based on chloroplast and nuclear DNA sequences.
Slotte T, Ceplitis A, Neuffer B, Hurka H, Lascoux M
American journal of botany 93 (11) 1714-1724 [2006-11-00; online 2006-11-01]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Identification of YhdA as a regulator of the Escherichia coli carbon storage regulation system.
Jonas K, Tomenius H, Römling U, Georgellis D, Melefors O
FEMS Microbiol. Lett. 264 (2) 232-237 [2006-11-00; online 2006-10-27]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Monophyly of Rhizaria and multigene phylogeny of unicellular bikonts.
Burki F, Pawlowski J
Molecular Biology and Evolution 23 (10) 1922-1930 [2006-10-00; online 2006-07-07]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Duration and degree of cyclosporin induced P-glycoprotein inhibition in the rat blood-brain barrier can be studied with PET.
Syvänen S, Blomquist G, Sprycha M, ..., Långström B, Bergström M
NeuroImage 32 (3) 1134-1141 [2006-09-00; online 2006-07-20]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Analysis of expressed sequence tags from a naked foraminiferan Reticulomyxa filosa.
Burki F, Nikolaev SI, Bolivar I, Guiard J, Pawlowski J
Genome 49 (8) 882-887 [2006-08-00; online 2006-10-13]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
A genomic study of the inter-ORF distances in Saccharomyces cerevisiae.
Pelechano V, García-Martínez J, Pérez-Ortín JE
Yeast 23 (9) 689-699 [2006-07-15; online 2006-07-18]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Continuum solvation models in the linear interaction energy method.
Carlsson J, Andér M, Nervall M, Aqvist J
J. Phys. Chem. B 110 (24) 12034-12041 [2006-06-22; online 2006-06-28]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
High-pressure liquid dispersion and fragmentation of flame-made silica agglomerates.
Wengeler R, Teleki A, Vetter M, Pratsinis SE, Nirschl H
Langmuir 22 (11) 4928-4935 [2006-05-23; online 2006-05-17]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
The Escherichia coli BarA-UvrY two-component system is a virulence determinant in the urinary tract.
Tomenius H, Pernestig AK, Jonas K, ..., Normark S, Melefors O
BMC Microbiol. 6 (-) 27 [2006-03-10; online 2006-03-10]
Kristina Jonas SciLifeLab Fellow
DOI Crossref
T2P-GFP: two-photon photoactivation of PA-GFP in the 720-840 nm spectral region.
Testa I, Schneider M, Barozzi S, ..., Faretta M, Diaspro A
- - (-) - [2006-02-09; online 2006-02-09]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
The wound response in tomato--role of jasmonic acid.
Wasternack C, Stenzel I, Hause B, ..., Feussner I, Miersch O
J. Plant Physiol. 163 (3) 297-306 [2006-02-00; online 2005-12-20]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II.
Rosenberg OS, Deindl S, Comolli LR, ..., Nairn AC, Kuriyan J
The FEBS journal 273 (4) 682-694 [2006-02-00; online 2006-01-31]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Molecular characterization of geminivirus-derived small RNAs in different plant species.
Akbergenov R, Si-Ammour A, Blevins T, ..., Hohn T, Pooggin MM
Nucleic Acids Res. 34 (2) 462-471 [2006-01-18; online 2006-01-18]
Claudia Kutter SciLifeLab Fellow
DOI Crossref
From Microscopy to Nanoscopy: How to Get and Read Optical Data at Single Molecule Level Using Confocal and Two-Photon Excitation Microscopy
Diaspro A, Bianchini P, Caorsi V, ..., Cannone F, Usai C
Springer [book chapter] (-) 187-207 [2006-01-14]
Ilaria Testa SciLifeLab Fellow

Year 2005

PubMed DOI Crossref
Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis.
Bienko M, Green CM, Crosetto N, ..., Hofmann K, Dikic I
Science (New York, N.Y.) 310 (5755) 1821-1824 [2005-12-16; online 2005-12-17]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Structure of the autoinhibited kinase domain of CaMKII and SAXS analysis of the holoenzyme.
Rosenberg OS, Deindl S, Sung RJ, Nairn AC, Kuriyan J
Cell 123 (5) 849-860 [2005-12-02; online 2005-12-06]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Solving the structure of plant photosystem I--biochemistry is vital.
Amunts A, Ben-Shem A, Nelson N
Photochem. Photobiol. Sci. 4 (12) 1011-1015 [2005-12-00; online 2005-09-19]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Biocatalysis in semi-aqueous and nearly anhydrous conditions.
Hudson EP, Eppler RK, Clark DS
Current Opinion in Biotechnology 16 (6) 637-643 [2005-12-00; online 2005-10-26]
Paul Hudson SciLifeLab Fellow
PubMed
Preparation and evaluation of (68)Ga-DOTA-hEGF for visualization of EGFR expression in malignant tumors.
Velikyan I, Sundberg AL, Lindhe O, ..., Långström B, Tolmachev V
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 46 (11) 1881-1888 [2005-11-00; online 2005-11-05]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Isolation of novel single-chain Cro proteins targeted for binding to the bcl-2 transcription initiation site by repertoire selection and subunit combinatorics.
Jonas K, Van Der Vries E, Nilsson MT, Widersten M
Protein Eng. Des. Sel. 18 (11) 537-546 [2005-11-00; online 2005-09-26]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Two-photon activation and excitation properties of PA-GFP in the 720-920-nm region.
Schneider M, Barozzi S, Testa I, Faretta M, Diaspro A
Biophysical Journal 89 (2) 1346-1352 [2005-08-00; online 2005-05-20]
Ilaria Testa SciLifeLab Fellow
DOI Crossref
Flame-coating of titania particles with silica
Teleki A, Pratsinis SE, Wegner K, Jossen R, Krumeich F
J. Mater. Res. 20 (5) 1336-1347 [2005-05-00; online 2011-03-03]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Absolute and relative entropies from computer simulation with applications to ligand binding.
Carlsson J, Aqvist J
J. Phys. Chem. B 109 (13) 6448-6456 [2005-04-07; online 2006-07-21]
Jens Carlsson SciLifeLab Fellow

Year 2004

PubMed DOI Crossref
Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.
Burki F, Kaessmann H
Nat Genet 36 (10) 1061-1063 [2004-10-00; online 2004-09-19]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Proton binding to proteins: pK(a) calculations with explicit and implicit solvent models.
Simonson T, Carlsson J, Case DA
J. Am. Chem. Soc. 126 (13) 4167-4180 [2004-04-07; online 2004-04-01]
Jens Carlsson SciLifeLab Fellow
DOI Crossref
Capacity ofSalvinia minima Baker to Tolerate and Accumulate As and Pb
Hoffmann T, Kutter C, Santamaría J
Eng. Life Sci. 4 (1) 61-65 [2004-02-05; online 2004-02-05]
Claudia Kutter SciLifeLab Fellow

Year 2003

PubMed DOI Crossref
Photocontrol of cell adhesion processes: model studies with cyclic azobenzene-RGD peptides.
Schütt M, Krupka SS, Milbradt AG, ..., Renner C, Moroder L
Chemistry & biology 10 (6) 487-490 [2003-06-00; online 2003-07-03]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Enzymes of jasmonate biosynthesis occur in tomato sieve elements.
Hause B, Hause G, Kutter C, Miersch O, Wasternack C
Plant Cell Physiol. 44 (6) 643-648 [2003-06-00; online 2003-06-27]
Claudia Kutter SciLifeLab Fellow

Year 2002

PubMed DOI Crossref
Phylogenetic position of Gromia oviformis Dujardin inferred from nuclear-encoded small subunit ribosomal DNA.
Burki F, Berney C, Pawlowski J
Protist 153 (3) 251-260 [2002-09-00; online 2002-10-23]
Fabien Burki SciLifeLab Fellow
SciLifeLab Data Centre
Publications 9.5.1