Mol Syst Biol

ISSN	1744-4292
ISSN-L	1744-4292
IUID	de2f3867b8ed4c538466558f892c69db
Modified	2020-11-27T13:12:56.716Z
Created	2018-12-03T14:28:37.688Z

Year 2025

PubMed DOI Crossref

Author Correction: Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.

Sommerauer C, Gallardo-Dodd CJ, Savva C, ..., Williams C, Kutter C

Mol Syst Biol 21 (9) 1282-1283 [2025-09-00; online 2025-06-12]

PubMed DOI Crossref

Longitudinal big biological data in the AI era.

Mardinoglu A, Turkez H, Shong M, ..., Hood L, Uhlen M

Mol Syst Biol 21 (9) 1147-1165 [2025-09-00; online 2025-08-05]

Year 2024

PubMed DOI Crossref

Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community.

Zhang C, Sánchez BJ, Li F, ..., Lu H, Kerkhoven EJ

Mol Syst Biol 20 (10) 1134-1150 [2024-10-00; online 2024-08-12]

PubMed DOI Crossref

Cellular energy regulates mRNA degradation in a codon-specific manner.

Tomaz da Silva P, Zhang Y, Theodorakis E, ..., Pelechano V, Gagneur J

Mol Syst Biol 20 (5) 506-520 [2024-05-00; online 2024-03-15]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.

Sommerauer C, Gallardo-Dodd CJ, Savva C, ..., Williams C, Kutter C

Mol Syst Biol 20 (4) 374-402 [2024-04-00; online 2024-03-08]

Claudia Kutter SciLifeLab Fellow

Year 2022

PubMed DOI Crossref

Distinct transcription kinetics of pluripotent cell states.

Shao R, Kumar B, Lidschreiber K, ..., Cramer P, Elsässer SJ

Mol Syst Biol 18 (1) e10407 [2022-01-00; online 2022-01-13]

SciLifeLab Fellow Simon Elsässer

Year 2021

PubMed DOI Crossref

Yeast metabolic innovations emerged via expanded metabolic network and gene positive selection.

Lu H, Li F, Yuan L, ..., Kerkhoven EJ, Nielsen J

Mol Syst Biol 17 (10) e10427 [2021-10-00; online 2021-10-23]

PubMed DOI Crossref

Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients.

Zeybel M, Altay O, Arif M, ..., Borén J, Mardinoglu A

Mol Syst Biol 17 (10) e10459 [2021-10-00; online 2021-10-26]

Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

A highly multiplexed quantitative phosphosite assay for biology and preclinical studies.

Keshishian H, McDonald ER, Mundt F, ..., Sellers WR, Carr SA

Mol Syst Biol 17 (9) e10156 [2021-09-00; online 2021-09-28]

Year 2020

PubMed DOI Crossref

Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder.

Stenström L, Mahdessian D, Gnann C, ..., Thul PJ, Lundberg E

Mol Syst Biol 16 (8) e9469 [2020-08-00; online 2020-08-04]

PubMed DOI Crossref

The protein expression profile of ACE2 in human tissues.

Hikmet F, Méar L, Edvinsson Å, ..., Uhlén M, Lindskog C

Mol Syst Biol 16 (7) e9610 [2020-07-00; online 2020-07-28]

PubMed DOI Crossref

The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease.

Zhang C, Bjornson E, Arif M, ..., Borén J, Mardinoglu A

Mol Syst Biol 16 (4) e9495 [2020-04-00; online 2020-04-28]

Adil Mardinoglu SciLifeLab Fellow

Year 2019

PubMed DOI Crossref

Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues.

Eraslan B, Wang D, Gusic M, ..., Kuster B, Gagneur J

Mol Syst Biol 15 (2) e8513 [2019-02-18; online 2019-02-18]

Year 2018

PubMed DOI Crossref

Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.

Azimi A, Caramuta S, Seashore-Ludlow B, ..., Uhlen M, Maddalo G

Mol Syst Biol 14 (3) e7858 [2018-03-05; online 2018-03-05]

Affiliated researcher

Year 2017

PubMed DOI Crossref

In situ genotyping of a pooled strain library after characterizing complex phenotypes.

Lawson MJ, Camsund D, Larsson J, ..., Fange D, Elf J

Mol Syst Biol 13 (10) 947 [2017-10-17; online 2017-10-17]

Affiliated researcher

PubMed DOI Crossref

Network analyses identify liver-specific targets for treating liver diseases.

Lee S, Zhang C, Liu Z, ..., Boren J, Mardinoglu A

Mol Syst Biol 13 (8) 938 [2017-08-21; online 2017-08-21]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow Simon Elsässer

PubMed DOI Crossref

Improving the phenotype predictions of a yeast genome-scale metabolic model by incorporating enzymatic constraints.

Sánchez BJ, Zhang C, Nilsson A, ..., Kerkhoven EJ, Nielsen J

Mol Syst Biol 13 (8) 935 [2017-08-03; online 2017-08-03]

Affiliated researcher Avlant Nilsson

PubMed DOI Crossref

Alternative TSSs are co-regulated in single cells in the mouse brain.

Karlsson K, Lönnerberg P, Linnarsson S

Mol Syst Biol 13 (5) 930 [2017-05-11; online 2017-05-11]

PubMed DOI Crossref

Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD.

Mardinoglu A, Bjornson E, Zhang C, ..., Taskinen MR, Boren J

Mol Syst Biol 13 (3) 916 [2017-03-02; online 2017-03-02]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

Year 2016

PubMed DOI Crossref

Gene-specific correlation of RNA and protein levels in human cells and tissues.

Edfors F, Danielsson F, Hallström BM, ..., Forsström B, Uhlén M

Mol Syst Biol 12 (10) 883 [2016-10-20; online 2016-10-20]

Affiliated researcher

PubMed DOI Crossref

Transcriptomics resources of human tissues and organs.

Uhlén M, Hallström BM, Lindskog C, ..., Pontén F, Nielsen J

Mol Syst Biol 12 (4) 862 [2016-04-04; online 2016-04-04]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

Year 2015

PubMed DOI Crossref

The gut microbiota modulates host amino acid and glutathione metabolism in mice

Mardinoglu A, Shoaie S, Bergentall M, ..., Bäckhed F, Nielsen J

Mol Syst Biol 11 (10) 834 [2015-10-00; online 2015-10-16]

Adil Mardinoglu SciLifeLab Fellow

PubMed DOI Crossref

Single-cell polyadenylation site mapping reveals 3' isoform choice variability.

Velten L, Anders S, Pekowska A, ..., Pelechano V, Steinmetz LM

Mol Syst Biol 11 (6) 812 [2015-06-03; online 2015-06-03]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

A high-throughput ChIP-Seq for large-scale chromatin studies.

Chabbert CD, Adjalley SH, Klaus B, ..., Pelechano V, Steinmetz LM

Mol Syst Biol 11 (1) 777 [2015-01-12; online 2015-01-12]

SciLifeLab Fellow Vicent Pelechano

Year 2014

PubMed DOI Crossref

Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs.

Adoue V, Schiavi A, Light N, ..., Syvänen AC, Pastinen T

Mol Syst Biol 10 (10) 754 [2014-10-16; online 2014-10-16]

PubMed DOI Crossref

Alternative polyadenylation diversifies post-transcriptional regulation by selective RNA-protein interactions

Gupta I, Clauder-Munster S, Klaus B, ..., Pelechano V, Steinmetz LM

Mol Syst Biol 10 (2) 719-719 [2014-03-20; online 2014-02-25]

SciLifeLab Fellow Vicent Pelechano

PubMed DOI Crossref

Identification of anticancer drugs for hepatocellular carcinoma through personalized genome-scale metabolic modeling.

Agren R, Mardinoglu A, Asplund A, ..., Uhlen M, Nielsen J

Mol Syst Biol 10 (3) 721 [2014-03-19; online 2014-03-19]

Year 2013

PubMed DOI Crossref

Integration of clinical data with a genome-scale metabolic model of the human adipocyte.

Mardinoglu A, Agren R, Kampf C, ..., Uhlen M, Nielsen J

Mol Syst Biol 9 (1) 649 [2013-03-21; online 2013-03-21]

Year 2012

PubMed DOI Crossref

Prediction and identification of sequences coding for orphan enzymes using genomic and metagenomic neighbours

Yamada T, Waller AS, Raes J, ..., Weissenbach J, Bork P

Mol Syst Biol 8 (-) - [2012-05-08; online 2012-05-08]

Aleksej Zelezniak SciLifeLab Fellow

Year 2011

PubMed DOI Crossref

Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics.

Zi Z, Feng Z, Chapnick DA, ..., Moustakas A, Liu X

Mol Syst Biol 7 (-) 492 [2011-05-24; online 2011-05-27]

Year 2010

PubMed DOI Crossref

Defining the transcriptome and proteome in three functionally different human cell lines.

Lundberg E, Fagerberg L, Klevebring D, ..., Mann M, Uhlen M

Mol Syst Biol 6 (-) 450 [2010-12-21; online 2010-12-24]