Mol Syst Biol

Cellular energy regulates mRNA degradation in a codon-specific manner.

Tomaz da Silva P, Zhang Y, Theodorakis E, ..., Pelechano V, Gagneur J

Mol Syst Biol 20 (5) 506-520 [2024-05-00; online 2024-03-15]

Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.

Sommerauer C, Gallardo-Dodd CJ, Savva C, ..., Williams C, Kutter C

Mol Syst Biol 20 (4) 374-402 [2024-04-00; online 2024-03-08]

Claudia Kutter SciLifeLab Fellow

Year 2022

Distinct transcription kinetics of pluripotent cell states.

Shao R, Kumar B, Lidschreiber K, ..., Cramer P, Elsässer SJ

Mol Syst Biol 18 (1) e10407 [2022-01-00; online 2022-01-13]

SciLifeLab Fellow Simon Elsässer

Year 2021

Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients.

Zeybel M, Altay O, Arif M, ..., Borén J, Mardinoglu A

Mol Syst Biol 17 (10) e10459 [2021-10-00; online 2021-10-26]

Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

Year 2020

The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease.

Zhang C, Bjornson E, Arif M, ..., Borén J, Mardinoglu A

Mol Syst Biol 16 (4) e9495 [2020-04-00; online 2020-04-28]

Adil Mardinoglu SciLifeLab Fellow

Year 2018

Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.

Azimi A, Caramuta S, Seashore-Ludlow B, ..., Uhlen M, Maddalo G

Mol Syst Biol 14 (3) e7858 [2018-03-05; online 2018-03-05]

Year 2017

In situ genotyping of a pooled strain library after characterizing complex phenotypes.

Lawson MJ, Camsund D, Larsson J, ..., Fange D, Elf J

Mol Syst Biol 13 (10) 947 [2017-10-17; online 2017-10-17]

Network analyses identify liver-specific targets for treating liver diseases.

Lee S, Zhang C, Liu Z, ..., Boren J, Mardinoglu A

Mol Syst Biol 13 (8) 938 [2017-08-21; online 2017-08-21]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow Simon Elsässer

Improving the phenotype predictions of a yeast genome-scale metabolic model by incorporating enzymatic constraints.

Sánchez BJ, Zhang C, Nilsson A, ..., Kerkhoven EJ, Nielsen J

Mol Syst Biol 13 (8) 935 [2017-08-03; online 2017-08-03]

Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD.

Mardinoglu A, Bjornson E, Zhang C, ..., Taskinen MR, Boren J

Mol Syst Biol 13 (3) 916 [2017-03-02; online 2017-03-02]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

Year 2016

Gene-specific correlation of RNA and protein levels in human cells and tissues.

Edfors F, Danielsson F, Hallström BM, ..., Forsström B, Uhlén M

Mol Syst Biol 12 (10) 883 [2016-10-20; online 2016-10-20]

Transcriptomics resources of human tissues and organs.

Uhlén M, Hallström BM, Lindskog C, ..., Pontén F, Nielsen J

Mol Syst Biol 12 (4) 862 [2016-04-04; online 2016-04-04]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

Year 2015

The gut microbiota modulates host amino acid and glutathione metabolism in mice

Mardinoglu A, Shoaie S, Bergentall M, ..., Bäckhed F, Nielsen J

Mol Syst Biol 11 (10) 834 [2015-10-00; online 2015-10-16]

Adil Mardinoglu SciLifeLab Fellow

Single-cell polyadenylation site mapping reveals 3' isoform choice variability.

Velten L, Anders S, Pekowska A, ..., Pelechano V, Steinmetz LM

Mol Syst Biol 11 (6) 812 [2015-06-03; online 2015-06-03]

A high-throughput ChIP-Seq for large-scale chromatin studies.

Chabbert CD, Adjalley SH, Klaus B, ..., Pelechano V, Steinmetz LM

Mol Syst Biol 11 (1) 777 [2015-01-12; online 2015-01-12]

Year 2014

Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs.

Adoue V, Schiavi A, Light N, ..., Syvänen AC, Pastinen T

Mol Syst Biol 10 (-) 754 [2014-10-16; online 2014-10-16]

Integration of clinical data with a genome-scale metabolic model of the human adipocyte

Mardinoglu A, Agren R, Kampf C, ..., Uhlen M, Nielsen J

Mol Syst Biol 9 (1) 649-649 [2014-04-28; online 2014-04-28]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

Identification of anticancer drugs for hepatocellular carcinoma through personalized genome-scale metabolic modeling

Agren R, Mardinoglu A, Asplund A, ..., Uhlen M, Nielsen J

Mol Syst Biol 10 (3) 721-721 [2014-03-28; online 2014-03-19]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

Alternative polyadenylation diversifies post-transcriptional regulation by selective RNA-protein interactions

Gupta I, Clauder-Munster S, Klaus B, ..., Pelechano V, Steinmetz LM

Mol Syst Biol 10 (2) 719-719 [2014-03-20; online 2014-02-25]

Year 2012

Prediction and identification of sequences coding for orphan enzymes using genomic and metagenomic neighbours

Yamada T, Waller AS, Raes J, ..., Weissenbach J, Bork P

Mol Syst Biol 8 (-) - [2012-05-08; online 2012-05-08]

Aleksej Zelezniak SciLifeLab Fellow

Year 2011

Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics.

Zi Z, Feng Z, Chapnick DA, ..., Moustakas A, Liu X

Mol Syst Biol 7 (-) 492 [2011-05-24; online 2011-05-27]

Year 2010

Defining the transcriptome and proteome in three functionally different human cell lines.

Lundberg E, Fagerberg L, Klevebring D, ..., Mann M, Uhlen M

Mol Syst Biol 6 (-) 450 [2010-12-21; online 2010-12-24]