Nielsen J, Fussenegger M, Keasling J, Lee SY, Liao JC, Prather K, Palsson B
Nat. Chem. Biol. 10 (5) 319-322 [2014-05-00; online 2014-04-20]
Biotechnology is a central focus in efforts to provide sustainable solutions for the provision of fuels, chemicals and materials. On the basis of a recent open discussion, we summarize the development of this field, highlighting the distinct but complementary approaches provided by metabolic engineering and synthetic biology for the creation of efficient cell factories to convert biomass and other feedstocks to desired chemicals.