Uhlen M

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Family name Uhlen
Given name Mathias
Initials M
ORCID

ORCID 0000-0002-4858-8056
Affiliations Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology, Stockholm, Sweden.
Center for Biosustainability, Danish Technical University, Copenhagen, Denmark.

122 publications

PubMed DOI Crossref
Proteome-scale autoantibody profiling in PSC: Associations with clinical phenotypes and evidence for neuroendocrine deregulations.
Cornillet M, Båve AL, Sun D, ..., Halfvarson J, Bergquist A
JHEP Rep 8 (3) 101719 [2026-03-00; online 2025-12-23]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Plasma protein profiling predicts cancer in patients with non-specific symptoms.
Wannberg F, Álvez MB, Qvick A, ..., Rosell A, Thålin C
Nat Commun 17 (1) 151 [2025-12-29; online 2025-12-29]
PubMed DOI Crossref
A human pan-disease blood atlas of the circulating proteome.
Álvez MB, Bergström S, Kenrick J, ..., Edfors F, Uhlén M
Science (New York, N.Y.) 390 (6779) eadx2678 [2025-12-18; online 2025-12-18]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Tissue-resident microbiota impacts colorectal cancer progression and prognosis.
Shi Z, Ren H, Lin C, ..., Sjöblom T, Zhong H
Nat Commun 17 (1) 346 [2025-12-07; online 2025-12-07]
DOI Crossref
OncoRisk: A state-of-the-art Web Server for bridging the oncogenic databases and pan-cancer cohorts to the translational oncology
Mardinoglu A, Song X, Green E, ..., Uhlén M, Zhang C
- - (-) - [2025-11-26; online 2025-11-26]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Deciphering the determinants of recombinant protein expression across the human secretome.
Masson HO, Di Giusto P, Kuo CC, ..., Rockberg J, Lewis NE
Proc. Natl. Acad. Sci. U.S.A. 122 (41) e2506036122 [2025-10-14; online 2025-10-07]
DOI Crossref
Targeting PKLR and lipogenic enzymes through JNK inhibition to develop a therapeutic strategy for MASLD and MASH
Mardinoglu A, Kim W, Li M, ..., Zhang C, Turkez H
- - (-) - [2025-09-25; online 2025-09-25]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Longitudinal big biological data in the AI era.
Mardinoglu A, Turkez H, Shong M, ..., Hood L, Uhlen M
Mol Syst Biol 21 (9) 1147-1165 [2025-09-00; online 2025-08-05]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Anticancer effects and mechanisms of Pulsatilla chinensis, Bupleurum chinense and Polyporus umbellatus on human lung carcinoma and hepatoma cells.
Li M, Kim W, Jin H, ..., Zhang C, Mardinoglu A
Comput Struct Biotechnol J 27 (-) 3066-3078 [2025-07-13; online 2025-07-13]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
A high-resolution subcellular map of proteins in cells with motile cilia
Bertilsson F, Hikmet F, Hansen JN, ..., Méar L, Lindskog C
- - (-) - [2025-03-18; online 2025-03-18]
DOI Crossref
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
Elife 13 (-) - [2025-02-11; online 2025-02-11]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
Elife - (-) - [2025-01-30; online 2025-01-30]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Author response: Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
- - (-) - [2025-01-30; online 2025-01-30]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
A spatiotemporal atlas of human spermatogenesis
Lindskog C, Hikmet F, Méar L, ..., Stukenborg JB, Uhlén M
- - (-) - [2025-01-17; online 2025-01-17]
DOI Crossref
PKLR-modulating compounds show promising effects for the treatment of hepatocellular carcinoma
Mardinoglu A, Kim W, Jin H, ..., Shi X, Zhang C
- - (-) - [2024-10-30; online 2024-10-30]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
A spatial single-cell type multiplex map of human spermatogenesis
Hikmet F, Méar L, Gustavsson J, ..., Uhlén M, Lindskog C
- - (-) - [2024-10-21; online 2024-10-21]
DOI Crossref
Dissecting autonomous enzymatic variability in single cells
Gnann C, Sigaeva A, Le T, ..., Axelsson U, Lundberg E
- - (-) - [2024-10-04; online 2024-10-04]
PubMed DOI Crossref
Unveiling the Molecular Mechanisms of Glioblastoma through an Integrated Network-Based Approach.
Kaynar A, Kim W, Ceyhan AB, ..., Shoaie S, Mardinoglu A
Biomedicines 12 (10) - [2024-10-01; online 2024-10-01]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Longitudinal analysis of genetic and environmental interplay in human metabolic profiles and the implication for metabolic health
Wang J, Zenere A, Wang X, ..., Uhlén M, Zhong W
- - (-) - [2024-09-24; online 2024-09-24]
DDLS Fellow Fredrik Edfors
DOI Crossref
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
- - (-) - [2024-09-12; online 2024-09-12]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Transient colonizing microbes promote gut dysbiosis and functional impairment.
Lee S, Meslier V, Bidkhori G, ..., Uhlen M, Shoaie S
NPJ Biofilms Microbiomes 10 (1) 80 [2024-09-08; online 2024-09-08]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Prognostic genome and transcriptome signatures in colorectal cancers.
Nunes L, Li F, Wu M, ..., Lin C, Sjöblom T
Nature 633 (8028) 137-146 [2024-09-00; online 2024-08-07]
PubMed DOI Crossref
Multiplexed mapping of the interactome of GPCRs with receptor activity-modifying proteins.
Kotliar IB, Bendes A, Dahl L, ..., Schwenk JM, Sakmar TP
Sci Adv 10 (31) eado9959 [2024-08-02; online 2024-07-31]
PubMed DOI Crossref
Global compositional and functional states of the human gut microbiome in health and disease.
Lee S, Portlock T, Le Chatelier E, ..., Uhlen M, Shoaie S
Genome Res 34 (6) 967-978 [2024-07-23; online 2024-07-23]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Discovery of Cell-Permeable Allosteric Inhibitors of Liver Pyruvate Kinase: Design and Synthesis of Sulfone-Based Urolithins.
Iqbal S, Islam MZ, Ashraf S, ..., Turkez H, Mardinoglu A
Int J Mol Sci 25 (14) - [2024-07-22; online 2024-07-22]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Discovery of a Therapeutic Agent for Glioblastoma Using a Systems Biology-Based Drug Repositioning Approach.
Kaynar A, Ozcan M, Li X, ..., Shoaie S, Mardinoglu A
Int J Mol Sci 25 (14) - [2024-07-18; online 2024-07-18]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood
Sdougkou K, Papazian S, Bonnefille B, ..., Martin LJ, Martin JW
- - (-) - [2024-04-17; online 2024-04-17]
DDLS Fellow Fredrik Edfors
DOI Crossref
A high-resolution spatial map of cilia-associated proteins based on characterization of the human fallopian tube-specific proteome
Lindskog C, Norradin FH, Digre A, ..., Hansen J, Uhlén M
- - (-) - [2024-02-09; online 2024-02-09]
PubMed DOI Crossref
Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.
Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M, ..., Trégouët DA, Odeberg J
Nat Commun 14 (1) 7752 [2023-11-27; online 2023-11-27]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Expanding the GPCR-RAMP interactome.
Kotliar IB, Bendes A, Dahl L, ..., Schwenk JM, Sakmar TP
bioRxiv - (-) - [2023-11-23; online 2023-11-23]
PubMed DOI Crossref
Open MoA: revealing the mechanism of action (MoA) based on network topology and hierarchy.
Liao X, Ozcan M, Shi M, ..., Mardinoglu A, Zhang C
Bioinformatics 39 (11) - [2023-11-01; online 2023-11-06]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Characterization of an in vitro steatosis model simulating activated de novo lipogenesis in MAFLD patients.
Kim W, Li M, Jin H, ..., Zhang C, Mardinoglu A
iScience 26 (10) 107727 [2023-10-20; online 2023-08-25]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Systematic transcriptional analysis of human cell lines for gene expression landscape and tumor representation.
Jin H, Zhang C, Zwahlen M, ..., Uhlén M, Mardinoglu A
Nat Commun 14 (1) 5417 [2023-09-05; online 2023-09-05]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
The acute effect of different NAD+ precursors included in the combined metabolic activators.
Li X, Yang H, Jin H, ..., Borén J, Mardinoglu A
Free Radic. Biol. Med. 205 (-) 77-89 [2023-08-20; online 2023-06-02]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
The development of blood protein profiles in extremely preterm infants follows a stereotypic evolution pattern.
Zhong W, Danielsson H, Brusselaers N, ..., Uhlén M, Hellström A
Commun Med (Lond) 3 (1) 107 [2023-08-02; online 2023-08-02]
PubMed DOI Crossref
Next generation pan-cancer blood proteome profiling using proximity extension assay.
Álvez MB, Edfors F, von Feilitzen K, ..., Fagerberg L, Uhlén M
Nat Commun 14 (1) 4308 [2023-07-18; online 2023-07-18]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.
Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M, ..., Trégouët DA, Odeberg J
Nat Commun 14 (1) 3280 [2023-06-07; online 2023-06-07]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Multiplexed selectivity screening of anti-GPCR antibodies.
Dahl L, Kotliar IB, Bendes A, ..., Sakmar TP, Schwenk JM
Sci Adv 9 (18) eadf9297 [2023-05-03; online 2023-05-03]
PubMed DOI Crossref
Revisiting the role of serine metabolism in hepatic lipogenesis.
Yang H, Zhang C, Turkez H, ..., Boren J, Mardinoglu A
Nat Metab 5 (5) 760-761 [2023-05-00; online 2023-05-11]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Prognostic whole-genome and transcriptome signatures in colorectal cancers
Nunes L, Li F, Wu M, ..., Lin C, Sjöblom T
- - (-) - [2023-03-30; online 2023-03-30]
DOI Crossref
The development of blood protein profiles in extremely preterm infants follows a stereotypic evolution pattern
Zhong W, Danielsson H, Brusselaers N, ..., Uhlen M, Hellström A
- - (-) - [2023-01-23; online 2023-01-23]
DOI Crossref
A human stomach cell type transcriptome atlas
Öling S, Struck E, Thorsen M, ..., Dusart P, Butler L
- - (-) - [2023-01-11; online 2023-01-11]
DOI Crossref
A tissue centric atlas of cell type transcriptome enrichment signatures
Dusart P, Öling S, Struck E, ..., Uhlén M, Butler L
- - (-) - [2023-01-10; online 2023-01-10]
DOI Crossref
Cover Feature: Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase (ChemBioChem 1/2023)
Battisti UM, Gao C, Nilsson O, ..., Mardinoglu A, Grøtli M
Chembiochem 24 (1) - [2023-01-03; online 2022-12-14]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase.
Battisti UM, Gao C, Nilsson O, ..., Mardinoglu A, Grøtli M
Chembiochem 24 (1) e202200339 [2023-01-03; online 2022-11-09]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Expression of substance P, NPY and their Receptors Is Altered in Major Depression
Barde S, Aguila J, Zhong W, ..., Hedlund E, Hökfelt T
- - (-) - [2022-12-15; online 2022-12-15]
DOI Crossref
Deciphering the determinants of recombinant protein yield across the human secretome
Masson HO, Kuo CC, Malm M, ..., Rockberg J, Lewis NE
- - (-) - [2022-12-14; online 2022-12-14]
DOI Crossref
Multiplexed selectivity screening of anti-GPCR antibodies
Dahl L, Kotliar IB, Bendes A, ..., Sakmar TP, Schwenk JM
- - (-) - [2022-11-24; online 2022-11-24]
PubMed DOI Crossref
Author Correction: Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level.
Wang F, Ding P, Liang X, ..., Lin L, Luo Y
Nat Commun 13 (1) 6748 [2022-11-08; online 2022-11-08]
DOI Crossref
Next generation pan-cancer blood proteome profiling using proximity extension assay
Uhlen M, Álvez MB, Edfors F, ..., Pontén F, Fagerberg L
- - (-) - [2022-11-01; online 2022-11-01]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Integrative functional analysis uncovers metabolic differences between Candida species.
Begum N, Lee S, Portlock TJ, ..., Moyes DL, Shoaie S
Commun Biol 5 (1) 1013 [2022-09-26; online 2022-09-26]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Host-mycobiome metabolic interactions in health and disease.
Begum N, Harzandi A, Lee S, ..., Moyes DL, Shoaie S
Gut Microbes 14 (1) 2121576 [2022-09-25; online 2022-09-25]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
The neuropeptide landscape of human prefrontal cortex.
Zhong W, Barde S, Mitsios N, ..., Mulder J, Hökfelt T
Proc. Natl. Acad. Sci. U.S.A. 119 (33) e2123146119 [2022-08-16; online 2022-08-10]
DOI Crossref
Genome-wide single cell annotation of the human protein-coding genes
Karlsson M, Álvez MB, Shi M, ..., Fagerberg L, Uhlén M
- - (-) - [2022-08-04; online 2022-08-04]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Author Correction: Spatiotemporal dissection of the cell cycle with single-cell proteogenomics.
Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan DP, Lundberg E
Nature 608 (7924) E32 [2022-08-00; online 2022-08-06]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level.
Wang F, Ding P, Liang X, ..., Lin L, Luo Y
Nat Commun 13 (1) 3620 [2022-06-24; online 2022-06-24]
PubMed DOI Crossref
Cell transcriptomic atlas of the non-human primate Macaca fascicularis.
Han L, Wei X, Liu C, ..., Esteban MA, Liu L
Nature 604 (7907) 723-731 [2022-04-00; online 2022-04-13]
PubMed DOI Crossref
Genome-wide annotation of protein-coding genes in pig.
Karlsson M, Sjöstedt E, Oksvold P, ..., Luo Y, Uhlen M
BMC Biol. 20 (1) 25 [2022-01-25; online 2022-01-25]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Transient Colonising Microbes Promote Gut Dysbiosis and Disease Pathology
Lee S, Meslier V, Bidkhori G, ..., Uhlen M, Shoaie S
- - (-) - [2022-00-00; online 2022-00-00]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Identification of Endothelial Proteins in Plasma Associated With Cardiovascular Risk Factors.
Iglesias MJ, Kruse LD, Sanchez-Rivera L, ..., Odeberg J, Butler LM
Arterioscler. Thromb. Vasc. Biol. 41 (12) 2990-3004 [2021-12-00; online 2021-10-28]
PubMed DOI Crossref
Targeted proteomics analysis of plasma proteins using recombinant protein standards for addition only workflows.
Kotol D, Hober A, Strandberg L, ..., Uhlén M, Edfors F
BioTechniques 71 (3) 473-483 [2021-09-00; online 2021-08-25]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
A single-cell type transcriptomics map of human tissues.
Karlsson M, Zhang C, Méar L, ..., Uhlén M, Lindskog C
Sci Adv 7 (31) - [2021-07-00; online 2021-07-28]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging.
Adori C, Daraio T, Kuiper R, ..., Bark C, Hökfelt T
Sci Adv 7 (30) - [2021-07-00; online 2021-07-21]
PubMed DOI Crossref
Publisher Correction: Altered perivascular fibroblast activity precedes ALS disease onset.
Månberg A, Skene N, Sanders F, ..., Nilsson P, Lewandowski SA
Nat. Med. 27 (7) 1308 [2021-07-00; online 2021-06-04]
DOI Crossref
Systems analysis reveals ageing-related perturbations in retinoids and sex hormones in Alzheimer’s and Parkinson’s diseases
Lam S, Hartmann N, Benfeitas R, ..., Knight R, Mardinoglu A
bioRxiv - (-) - [2021-06-10; online 2021-06-10]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
A porcine brain-wide RNA editing landscape.
Huang J, Lin L, Dong Z, ..., Bolund L, Luo Y
Commun Biol 4 (1) 717 [2021-06-10; online 2021-06-10]
DOI Crossref
Multi-omics analysis reveals the impact of microbiota on host metabolism in hepatic steatosis
Zeybel M, Arif M, Li X, ..., Borén J, Mardinoglu A
bioRxiv - (-) - [2021-05-23; online 2021-05-23]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Next generation plasma proteome profiling to monitor health and disease.
Zhong W, Edfors F, Gummesson A, ..., Fagerberg L, Uhlén M
Nat Commun 12 (1) 2493 [2021-05-03; online 2021-05-03]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Revealing the Metabolic Alterations during Biofilm Development of Burkholderia cenocepacia Based on Genome-Scale Metabolic Modeling.
Altay O, Zhang C, Turkez H, ..., Uhlén M, Mardinoglu A
Metabolites 11 (4) - [2021-04-05; online 2021-04-05]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Global and temporal state of the human gut microbiome in health and disease
Shoaie S, Lee S, Almeida M, ..., Ehrlich S, Uhlen M
- - (-) - [2021-04-01; online 2021-04-01]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Altered perivascular fibroblast activity precedes ALS disease onset.
Månberg A, Skene N, Sanders F, ..., Nilsson P, Lewandowski SA
Nat. Med. 27 (4) 640-646 [2021-04-00; online 2021-04-15]
PubMed DOI Crossref
Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson's disease.
Rosario D, Bidkhori G, Lee S, ..., Mardinoglu A, Shoaie S
Cell Reports 34 (9) 108807 [2021-03-02; online 2021-03-04]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Association of CSF proteins with tau and amyloid β levels in asymptomatic 70-year-olds.
Remnestål J, Bergström S, Olofsson J, ..., Nilsson P, Månberg A
Alzheimers Res Ther 13 (1) 54 [2021-03-02; online 2021-03-02]
PubMed DOI Crossref
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics.
Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan DP, Lundberg E
Nature 590 (7847) 649-654 [2021-02-00; online 2021-02-24]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Combined Metabolic Activators Decrease Liver Steatosis by Activating Mitochondrial Metabolism in a Golden Syrian Hamster Study
Yang H, Mayneris-Perxachs J, Boqué N, ..., Mardinoglu A, Caimari A
- - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
A Network-Based Approach Reveals the Dysregulated Transcriptional Regulation in Non- Alcohol Fatty Liver Disease
Yang H, Arif M, Yuan M, ..., Zhang C, Mardinoglu A
- - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Drug Repositioning for Clear Cell Renal Cell Carcinoma Based on Stratification of Patients
Li X, Kim W, Juszczak K, ..., Zhang C, Mardinoglu A
- - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
A porcine brain-wide RNA editing landscape
Huang J, Lin L, Dong Z, ..., Bolund L, Luo Y
- - (-) - [2020-12-11; online 2020-12-11]
PubMed DOI Crossref
A high-stringency blueprint of the human proteome.
Adhikari S, Nice EC, Deutsch EW, ..., Aebersold R, Baker MS
Nat Commun 11 (1) 5301 [2020-10-16; online 2020-10-16]
PubMed DOI Crossref
Profiles of histidine-rich glycoprotein associate with age and risk of all-cause mortality.
Hong MG, Dodig-Crnković T, Chen X, ..., Magnusson PK, Schwenk JM
Life Sci. Alliance 3 (10) - [2020-10-00; online 2020-07-31]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Integration of molecular profiles in a longitudinal wellness profiling cohort.
Tebani A, Gummesson A, Zhong W, ..., Uhlen M, Fagerberg L
Nat Commun 11 (1) 4487 [2020-09-08; online 2020-09-08]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder.
Stenström L, Mahdessian D, Gnann C, ..., Thul PJ, Lundberg E
Mol Syst Biol 16 (8) e9469 [2020-08-00; online 2020-08-04]
DDLS Fellow Wei Ouyang
PubMed DOI Crossref
The protein expression profile of ACE2 in human tissues.
Hikmet F, Méar L, Edvinsson Å, ..., Uhlén M, Lindskog C
Mol Syst Biol 16 (7) e9610 [2020-07-00; online 2020-07-28]
PubMed DOI Crossref
Whole-genome sequence association analysis of blood proteins in a longitudinal wellness cohort.
Zhong W, Gummesson A, Tebani A, ..., Fagerberg L, Uhlén M
Genome Med 12 (1) 53 [2020-06-23; online 2020-06-23]
DDLS Fellow Fredrik Edfors
DOI Crossref
The protein expression profile of ACE2 in human tissues
Hikmet F, Méar L, Edvinsson Å, ..., Uhlén M, Lindskog C
- - (-) - [2020-04-03; online 2020-04-03]
PubMed DOI Crossref
The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease.
Zhang C, Bjornson E, Arif M, ..., Borén J, Mardinoglu A
Mol Syst Biol 16 (4) e9495 [2020-04-00; online 2020-04-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
An atlas of human metabolism.
Robinson JL, Kocabaş P, Wang H, ..., Uhlén M, Nielsen J
Sci Signal 13 (624) eaaz1482 [2020-03-24; online 2020-03-24]
Adil Mardinoglu Avlant Nilsson DDLS Fellow SciLifeLab Fellow
DOI Crossref
Facets of individual-specific health signatures determined from longitudinal plasma proteome profiling
Dodig-Crnković T, Hong MG, Thomas CE, ..., Uhlén M, Schwenk JM
bioRxiv - (-) - [2020-03-15; online 2020-03-15]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
An atlas of the protein-coding genes in the human, pig, and mouse brain.
Sjöstedt E, Zhong W, Fagerberg L, ..., Uhlén M, Mulder J
Science (New York, N.Y.) 367 (6482) eaay5947 [2020-03-06; online 2020-03-07]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Expression and regulation of FRMD6 in mouse DRG neurons and spinal cord after nerve injury.
Lyu C, Lyu GW, Mulder J, ..., Hökfelt T, Sten Shi TJ
Sci Rep 10 (1) 1880 [2020-02-05; online 2020-02-05]
DOI Crossref
Evolution from adherent to suspension – systems biology of HEK293 cell line development
Malm M, Saghaleyni R, Lundqvist M, ..., Nielsen J, Rockberg J
- - (-) - [2020-01-30; online 2020-01-30]
DOI Crossref
Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder
Stenström L, Mahdessian D, Gnann C, ..., Thul PJ, Lundberg E
bioRxiv - (-) - [2020-01-30; online 2020-01-30]
DDLS Fellow Wei Ouyang
DOI Crossref
Discovery of Functional Alternatively Spliced <i>PKM</i> Transcripts in Human Cancers
Li X, Zhang C, Kim W, ..., Uhlen M, Mardinoglu A
- - (-) - [2020-00-00; online 2020-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells.
Uhlen M, Karlsson MJ, Zhong W, ..., Fagerberg L, Brodin P
Science (New York, N.Y.) 366 (6472) eaax9198 [2019-12-20; online 2019-12-21]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
The human secretome.
Uhlén M, Karlsson MJ, Hober A, ..., Fagerberg L, Sivertsson Å
Sci Signal 12 (609) eaaz0274 [2019-11-26; online 2019-11-26]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Multiplexed analysis of the secretin-like GPCR-RAMP interactome.
Lorenzen E, Dodig-Crnković T, Kotliar IB, ..., Schwenk JM, Sakmar TP
Sci Adv 5 (9) eaaw2778 [2019-09-00; online 2019-09-18]
PubMed DOI Crossref
Single-cell RNA-seq variant analysis for exploration of genetic heterogeneity in cancer.
Fasterius E, Uhlén M, Al-Khalili Szigyarto C
Sci Rep 9 (1) 9524 [2019-07-02; online 2019-07-02]
DOI Crossref
iNetModels 2.0: an interactive visualization and database of multi-omics data
Arif M, Zhang C, Li X, ..., Uhlen M, Mardinoglu A
bioRxiv - (-) - [2019-06-08; online 2019-06-08]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Multiplexed Analysis of the Secretin-like GPCR-RAMP Interactome
Lorenzen E, Dodig-Crnković T, Kotliar IB, ..., Schwenk JM, Sakmar TP
- - (-) - [2019-04-06; online 2019-04-06]
PubMed DOI Crossref
Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function.
Liu Z, Zhang C, Lee S, ..., Boren J, Mardinoglu A
Metab. Eng. 52 (-) 263-272 [2019-03-00; online 2019-01-04]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues.
Eraslan B, Wang D, Gusic M, ..., Kuster B, Gagneur J
Mol Syst Biol 15 (2) e8513 [2019-02-18; online 2019-02-18]
DOI Crossref
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics
Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan D, Lundberg E
bioRxiv - (-) - [2019-02-07; online 2019-02-07]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Chromophore pre-maturation for improved speed and sensitivity of split-GFP monitoring of protein secretion.
Lundqvist M, Thalén N, Volk AL, ..., Uhlen M, Rockberg J
Sci Rep 9 (1) 310 [2019-01-22; online 2019-01-22]
PubMed DOI Crossref
Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes.
Bidkhori G, Benfeitas R, Klevstig M, ..., Boren J, Mardinoglu A
Proc. Natl. Acad. Sci. U.S.A. 115 (50) E11874-E11883 [2018-12-11; online 2018-11-27]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
The human secretome – the proteins secreted from human cells
Uhlen M, Tegel H, Sivertsson Å, ..., Schiavone LH, Hober S
- - (-) - [2018-11-26; online 2018-11-26]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
DOI Crossref
Screening a Resource of Recombinant Protein Fragments for Targeted Proteomics
Edfors F, Forsström B, Vunk H, ..., Schwenk JM, Uhlen M
- - (-) - [2018-11-19; online 2018-11-19]
DDLS Fellow Fredrik Edfors
DOI Crossref
Profiles of circulating histidine-rich glycoprotein associate with chronological age and risk of all-cause mortality
Hong MG, Dodig-Crnković T, Chen X, ..., Magnusson PKE, Schwenk JM
- - (-) - [2018-11-09; online 2018-11-09]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Enhanced validation of antibodies for research applications.
Edfors F, Hober A, Linderbäck K, ..., Forsström B, Uhlen M
Nat Commun 9 (1) 4130 [2018-10-08; online 2018-10-08]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
A systems-approach reveals human nestin is an endothelial-enriched, angiogenesis-independent intermediate filament protein.
Dusart P, Fagerberg L, Perisic L, ..., Odeberg J, Butler LM
Sci Rep 8 (1) 14668 [2018-10-02; online 2018-10-02]
DOI Crossref
Quantification and discovery of sequence determinants of protein per mRNA amount in 29 human tissues
Eraslan B, Wang D, Gusic M, ..., Kuster B, Gagneur J
- - (-) - [2018-06-27; online 2018-06-27]
DOI Crossref
A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
Wang D, Eraslan B, Wieland T, ..., Hahne H, Kuster B
bioRxiv - (-) - [2018-06-27; online 2018-06-27]
PubMed DOI Crossref
Systems biology in hepatology: approaches and applications.
Mardinoglu A, Boren J, Smith U, Uhlen M, Nielsen J
Nat Rev Gastroenterol Hepatol 15 (6) 365-377 [2018-06-00; online 2018-04-25]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.
Mardinoglu A, Wu H, Bjornson E, ..., Taskinen MR, Borén J
Cell Metab. 27 (3) 559-571.e5 [2018-03-06; online 2018-02-15]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.
Azimi A, Caramuta S, Seashore-Ludlow B, ..., Uhlen M, Maddalo G
Mol Syst Biol 14 (3) e7858 [2018-03-05; online 2018-03-05]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Network analyses identify liver-specific targets for treating liver diseases.
Lee S, Zhang C, Liu Z, ..., Boren J, Mardinoglu A
Mol Syst Biol 13 (8) 938 [2017-08-21; online 2017-08-21]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
A pathology atlas of the human cancer transcriptome.
Uhlen M, Zhang C, Lee S, ..., Mardinoglu A, Ponten F
Science (New York, N.Y.) 357 (6352) eaan2507 [2017-08-18; online 2017-08-19]
Adil Mardinoglu Affiliated researcher DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
A subcellular map of the human proteome.
Thul PJ, Åkesson L, Wiking M, ..., Uhlén M, Lundberg E
Science (New York, N.Y.) 356 (6340) eaal3321 [2017-05-26; online 2017-05-11]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD.
Mardinoglu A, Bjornson E, Zhang C, ..., Taskinen MR, Boren J
Mol Syst Biol 13 (3) 916 [2017-03-02; online 2017-03-02]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Response to: Should we ignore western blots when selecting antibodies for other applications?
Uhlen M
Nat. Methods 14 (3) 215-216 [2017-02-28; online 2017-03-01]
PubMed DOI Crossref
Gene-specific correlation of RNA and protein levels in human cells and tissues.
Edfors F, Danielsson F, Hallström BM, ..., Forsström B, Uhlén M
Mol Syst Biol 12 (10) 883 [2016-10-20; online 2016-10-20]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
A proposal for validation of antibodies.
Uhlen M, Bandrowski A, Carr S, ..., Snyder M, Yamamoto T
Nat. Methods 13 (10) 823-827 [2016-10-00; online 2016-09-05]
DOI Crossref
Deciphering the tissue specificity of the protein secretory pathway in humans
Feizi A, Gatto F, Uhlen M, Nielsen J
- - (-) - [2016-08-24; online 2016-08-24]
SciLifeLab Data Centre
Publications 9.5.1