Marc Friedländer

MapToCleave: High-throughput profiling of microRNA biogenesis in living cells.

Kang W, Fromm B, Houben AJ, ..., Biryukova I, Friedländer MR

Cell Reports 37 (7) 110015 [2021-11-16; online 2021-11-18]

Corrigendum: Ancient microRNA profiles of 14,300-yr-old canid samples confirm taxonomic origin and provide glimpses into tissue-specific gene regulation from the Pleistocene.

Fromm B, Tarbier M, Smith O, ..., Gilbert MTP, Friedländer MR

RNA 27 (10) 1291 [2021-10-00; online 2021-09-18]

A combined approach for single-cell mRNA and intracellular protein expression analysis.

Reimegård J, Tarbier M, Danielsson M, ..., Friedländer MR, Gallant CJ

Commun Biol 4 (1) 624 [2021-05-25; online 2021-05-25]

Environmental Enrichment Induces Epigenomic and Genome Organization Changes Relevant for Cognition.

Espeso-Gil S, Holik AZ, Bonnin S, ..., Hor CN, Ossowski S

Front Mol Neurosci 14 (-) 664912 [2021-05-05; online 2021-05-05]

DOI Crossref

OUP accepted manuscript

Nucleic Acids Research - (-) - [2021-00-00; online 2021-00-00]

Year 2020

Ancient microRNA profiles of a 14,300-year-old canid samples confirm taxonomic origin and give glimpses into tissue-specific gene regulation from the Pleistocene.

Fromm B, Tarbier M, Smith O, ..., Gilbert TP, Friedlander MR

RNA - (-) - [2020-12-15; online 2020-12-15]

Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development.

Malkani S, Chin CR, Cekanaviciute E, ..., Mason CE, Beheshti A

Cell Reports 33 (10) 108448 [2020-12-08; online 2020-11-25]

Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells.

Tarbier M, Mackowiak SD, Frade J, ..., Gallant CJ, Friedländer MR

Nat Commun 11 (1) 5445 [2020-10-28; online 2020-10-28]

Fellows programme Magda Bienko Marc Friedländer

Male swarming aggregation pheromones increase female attraction and mating success among multiple African malaria vector mosquito species.

Mozūraitis R, Hajkazemian M, Zawada JW, ..., Borg-Karlson AK, Emami SN

Nat Ecol Evol 4 (10) 1395-1401 [2020-10-00; online 2020-08-03]

Quo vadis microRNAs?

Fromm B, Keller A, Yang X, ..., Peterson KJ, Griffiths-Jones S

Trends in Genetics 36 (7) 461-463 [2020-07-00; online 2020-04-16]

Dose and time effects of solar-simulated ultraviolet radiation on the in vivo human skin transcriptome.

Bustamante M, Hernandez-Ferrer C, Tewari A, ..., Nieuwenhuijsen M, Young AR

Br. J. Dermatol. 182 (6) 1458-1468 [2020-06-00; online 2019-11-27]

Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API.

Desvignes T, Loher P, Eilbeck K, ..., Halushka MK, Pantano L

Bioinformatics 36 (3) 698-703 [2020-02-01; online 2019-09-11]

MirGeneDB 2.0: the metazoan microRNA complement.

Fromm B, Domanska D, Høye E, ..., Friedländer MR, Peterson KJ

Nucleic Acids Res. 48 (D1) D1172 [2020-01-08; online 2019-10-24]

Year 2019

Cytoplasmic protein misfolding titrates Hsp70 to activate nuclear Hsf1.

Masser AE, Kang W, Roy J, ..., Friedländer MR, Andréasson C

Elife 8 (-) - [2019-09-25; online 2019-09-25]

EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks.

Domingo-Prim J, Endara-Coll M, Bonath F, ..., Huertas P, Visa N

Nat Commun 10 (1) 2135 [2019-05-13; online 2019-05-13]

Plant microRNAs in human sera are likely contaminants.

Fromm B, Kang W, Rovira C, ..., Friedländer MR, Tosar JP

J Nutr Biochem 65 (-) 139-140 [2019-03-00; online 2018-09-05]

Evolutionary Implications of the microRNA- and piRNA Complement of Lepidodermella squamata (Gastrotricha).

Fromm B, Tosar JP, Aguilera F, ..., Bachmann L, Hejnol A

Noncoding RNA 5 (1) 19 [2019-02-22; online 2019-02-22]

The Circulating Transcriptome as a Source of Biomarkers for Melanoma.

Solé C, Tramonti D, Schramm M, ..., Middleton MR, Lawrie CH

Cancers (Basel) 11 (1) 70 [2019-01-10; online 2019-01-10]

Year 2018

Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks.

Bonath F, Domingo-Prim J, Tarbier M, Friedländer MR, Visa N

Nucleic Acids Res. 46 (22) 11869-11882 [2018-12-14; online 2018-11-13]

miRTrace reveals the organismal origins of microRNA sequencing data.

Kang W, Eldfjell Y, Fromm B, ..., Biryukova I, Friedländer MR

Genome Biol. 19 (1) 213 [2018-12-04; online 2018-12-04]

Control of hepatic gluconeogenesis by Argonaute2.

Yan X, Wang Z, Bishop CA, ..., Willnow TE, Poy MN

Mol Metab 18 (-) 15-24 [2018-12-00; online 2018-10-09]

microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function.

Langlet F, Tarbier M, Haeusler RA, ..., Friedländer MR, Accili D

Mol Metab 17 (-) 49-60 [2018-11-00; online 2018-08-11]

Year 2017

The acute effects of ultraviolet radiation on the blood transcriptome are independent of plasma 25OHD3.

Bustamante M, Hernandez-Ferrer C, Sarria Y, ..., Nieuwenhuijsen M, Young AR

Environ. Res. 159 (-) 239-248 [2017-11-00; online 2017-09-18]

Affiliated researcher Fellows programme Marc Friedländer

Signatures of positive selection reveal a universal role of chromatin modifiers as cancer driver genes.

Zapata L, Susak H, Drechsel O, ..., Estivill X, Ossowski S

Sci Rep 7 (1) 13124 [2017-10-13; online 2017-10-13]

Affiliated researcher Fellows programme Marc Friedländer

Differential Impact of Glucose Administered Intravenously and Orally on Circulating miR-375 Levels in Human Subjects.

Yan X, Wang Z, Westberg-Rasmussen S, ..., Gregersen S, Poy MN

J. Clin. Endocrinol. Metab. 102 (10) 3749-3755 [2017-10-01; online 2017-10-04]

Affiliated researcher Fellows programme Marc Friedländer

A Fluorophore Fusion Construct of Human Profilin I with Non-Compromised Poly(L-Proline) Binding Capacity Suitable for Imaging.

Nejedla M, Li Z, Masser AE, ..., Friedländer MR, Karlsson R

J. Mol. Biol. 429 (7) 964-976 [2017-04-07; online 2017-01-08]

Affiliated researcher Fellows programme Marc Friedländer

Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts.

Kang W, Bang-Berthelsen CH, Holm A, ..., Estivill X, Friedländer MR

RNA 23 (4) 433-445 [2017-04-00; online 2017-01-06]

Affiliated researcher Fellows programme Marc Friedländer

Year 2016

Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing.

Ferreira PG, Oti M, Barann M, ..., Guigó R, Sammeth M

Sci Rep 6 (1) 32406 [2016-09-12; online 2016-09-12]

Affiliated researcher Fellows programme Marc Friedländer

Cytosolic splice isoform of Hsp70 nucleotide exchange factor Fes1 is required for the degradation of misfolded proteins in yeast.

Gowda NK, Kaimal JM, Masser AE, ..., Friedländer MR, Andréasson C

Mol. Biol. Cell 27 (8) 1210-1219 [2016-04-15; online 2016-02-24]

Affiliated researcher Fellows programme Marc Friedländer

Specific small-RNA signatures in the amygdala at premotor and motor stages of Parkinson's disease revealed by deep sequencing analysis.

Pantano L, Friedländer MR, Escaramís G, ..., Estivill X, Martí E

Bioinformatics 32 (5) 673-681 [2016-03-01; online 2015-11-02]

Next-generation sequencing of the basal cell carcinoma miRNome and a description of novel microRNA candidates under neoadjuvant vismodegib therapy: an integrative molecular and surgical case study.

Sand M, Bechara FG, Gambichler T, ..., Schnabel R, Hessam S

Ann. Oncol. 27 (2) 332-338 [2016-02-00; online 2015-11-16]

Affiliated researcher Fellows programme Marc Friedländer

Year 2015

miR-184 Regulates Pancreatic β-Cell Function According to Glucose Metabolism.

Tattikota SG, Rathjen T, Hausser J, ..., Friedländer MR, Poy MN

J Biol Chem 290 (33) 20284-20294 [2015-08-14; online 2015-07-07]

Affiliated researcher Fellows programme Marc Friedländer

Human genomics. Effect of predicted protein-truncating genetic variants on the human transcriptome.

Rivas MA, Pirinen M, Conrad DF, ..., Lappalainen T, MacArthur DG

Science (New York, N.Y.) 348 (6235) 666-669 [2015-05-08; online 2015-05-09]

Year 2014

Tandem RNA chimeras contribute to transcriptome diversity in human population and are associated with intronic genetic variants.

Greger L, Su J, Rung J, ..., Dermitzakis ET, Brazma A

PLoS ONE 9 (8) e104567 [2014-08-18; online 2014-08-18]

Affiliated researcher Fellows programme Marc Friedländer

Characterisation of novel microRNAs in the Black flying fox (Pteropus alecto) by deep sequencing.

Cowled C, Stewart CR, Likic VA, ..., Bean AG, Wang LF

BMC Genomics 15 (1) 682 [2014-08-15; online 2014-08-15]

Evidence for the biogenesis of more than 1,000 novel human microRNAs.

Friedländer MR, Lizano E, Houben AJ, ..., Martí E, Estivill X

Genome Biol. 15 (4) R57 [2014-04-07; online 2014-04-07]

Year 2013

Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories

't Hoen PAC, Friedländer MR, Almlöf J, ..., Dermitzakis ET, Lappalainen T

Nat Biotechnol 31 (11) 1015-1022 [2013-11-00; online 2013-09-15]

Affiliated researcher Marc Friedländer

Transcriptome and genome sequencing uncovers functional variation in humans

Lappalainen T, Sammeth M, Friedländer MR, ..., Estivill X, Dermitzakis ET

Nature 501 (7468) 506-511 [2013-09-00; online 2013-09-15]

Affiliated researcher Marc Friedländer

MicroRNA expression profiling in blood from fragile X-associated tremor/ataxia syndrome patients

Alvarez-Mora MI, Rodriguez-Revenga L, Madrigal I, ..., Estivill X, Milà M

- 12 (6) 595-603 [2013-08-00; online 2013-07-24]

Upregulation of a small vault RNA (svtRNA2-1a) is an early event in Parkinson disease and induces neuronal dysfunction.

Miñones-Moyano E, Friedländer MR, Pallares J, ..., Estivill X, Martí E

RNA Biol 10 (7) 1093-1106 [2013-07-00; online 2013-05-01]

Global profiling of miRNAs and the hairpin precursors: insights into miRNA processing and novel miRNA discovery

Li N, You X, Chen T, ..., Hu Y, Chen W

Nucleic Acids Res. 41 (6) 3619-3634 [2013-04-00; online 2013-02-08]

Year 2012

Select microRNAs are essential for early development in the sea urchin

Song JL, Stoeckius M, Maaskola J, ..., Rajewsky N, Wessel GM

Developmental Biology 362 (1) 104-113 [2012-02-00; online 2012-02-00]

miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades

Friedländer MR, Mackowiak SD, Li N, Chen W, Rajewsky N

Nucleic Acids Res. 40 (1) 37-52 [2012-01-00; online 2011-09-10]

Year 2010

Deciphering the porcine intestinal microRNA transcriptome

Sharbati S, Friedlander MR, Sharbati J, ..., Rajewsky N, Einspanier R

BMC Genomics 11 (1) 275 [2010-00-00; online 2010-00-00]

Year 2009

Large-scale sorting of C. elegans embryos reveals the dynamics of small RNA expression.

Stoeckius M, Maaskola J, Colombo T, ..., Piano F, Rajewsky N

Nat. Methods 6 (10) 745-751 [2009-10-00; online 2009-09-06]

High-resolution profiling and discovery of planarian small RNAs.

Friedländer MR, Adamidi C, Han T, ..., Kim JK, Rajewsky N

Proc. Natl. Acad. Sci. U.S.A. 106 (28) 11546-11551 [2009-07-14; online 2009-06-29]

Year 2008

A human snoRNA with microRNA-like functions.

Ender C, Krek A, Friedländer MR, ..., Rajewsky N, Meister G

Mol. Cell 32 (4) 519-528 [2008-11-21; online 2008-11-26]