Elsässer SJ

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Family name Elsässer
Given name Simon J
Initials SJ
ORCID

ORCID 0000-0001-8724-4849
Affiliations Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

39 publications

PubMed DOI Crossref
Dynamic antagonism between key repressive pathways maintains the placental epigenome.
Weigert R, Hetzel S, Bailly N, ..., Smith ZD, Meissner A
Nat. Cell Biol. 25 (4) 579-591 [2023-04-00; online 2023-04-06]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation.
Stolz P, Mantero AS, Tvardovskiy A, ..., Elsässer SJ, Bultmann S
Nucleic Acids Res. 50 (15) 8491-8511 [2022-08-26; online 2022-07-30]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Polycomb repressive complex 2 shields naïve human pluripotent cells from trophectoderm differentiation.
Kumar B, Navarro C, Winblad N, ..., Lanner F, Elsässer SJ
Nat. Cell Biol. 24 (6) 845-857 [2022-06-00; online 2022-05-30]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress.
Larsen BD, Benada J, Yung PYK, ..., Bartek J, Sørensen CS
Science (New York, N.Y.) 376 (6592) 476-483 [2022-04-29; online 2022-04-28]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
minute: A MINUTE-ChIP data analysis workflow
Navarro C, Martin M, Elsässer S
- - (-) - [2022-03-17; online 2022-03-17]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43.
Garcia Morato J, Hans F, von Zweydorf F, ..., Neumann M, Kahle PJ
Nat Commun 13 (1) 1223 [2022-03-09; online 2022-03-09]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Genome-wide mapping of G-quadruplex structures with CUT&Tag.
Lyu J, Shao R, Kwong Yung PY, Elsässer SJ
Nucleic Acids Res. 50 (3) e13 [2022-02-22; online 2021-11-19]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Revisiting sORFs: overcoming challenges to identify and characterize functional microproteins.
Schlesinger D, Elsässer SJ
FEBS J. 289 (1) 53-74 [2022-01-00; online 2021-02-24]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Distinct transcription kinetics of pluripotent cell states.
Shao R, Kumar B, Lidschreiber K, ..., Cramer P, Elsässer SJ
Mol Syst Biol 18 (1) e10407 [2022-01-00; online 2022-01-13]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output.
Kanellis DC, Espinoza JA, Zisi A, ..., Lindström MS, Bartek J
Sci Adv 7 (32) - [2021-08-00; online 2021-08-04]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2.
Roxhed N, Bendes A, Dale M, ..., Fredolini C, Schwenk JM
Nat Commun 12 (1) 3695 [2021-06-17; online 2021-06-17]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Towards policies that capture the expected value of biomolecular diversity for drug discovery, human health, and well-being.
Pesic M, Egamberdieva D, Kolodziejczyk B, ..., Neergheen VS, Kagansky A
Biol Futur 72 (2) 119-125 [2021-06-00; online 2020-09-07]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Direct detection of SARS-CoV-2 using non-commercial RT-LAMP reagents on heat-inactivated samples.
Alekseenko A, Barrett D, Pareja-Sanchez Y, ..., Yin X, Pelechano V
Sci Rep 11 (1) 1820 [2021-01-19; online 2021-01-19]
SciLifeLab Fellow Simon Elsässer Vicent Pelechano
PubMed DOI Crossref
Universal Single-Residue Terminal Labels for Fluorescent Live Cell Imaging of Microproteins.
Lafranchi L, Schlesinger D, Kimler KJ, Elsässer SJ
Journal of the American Chemical Society 142 (47) 20080-20087 [2020-11-25; online 2020-11-11]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility.
Navarro C, Lyu J, Katsori AM, Caridha R, Elsässer SJ
Nat Commun 11 (1) 5095 [2020-10-09; online 2020-10-09]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution.
Björkman A, Johansen SL, Lin L, ..., Bartek J, Schou KB
Genes Dev. 34 (15-16) 1065-1074 [2020-08-01; online 2020-06-19]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Site-Specific Incorporation of Two ncAAs for Two-Color Bioorthogonal Labeling and Crosslinking of Proteins on Live Mammalian Cells.
Meineke B, Heimgärtner J, Eirich J, Landreh M, Elsässer SJ
Cell Reports 31 (12) 107811 [2020-06-23; online 2020-06-25]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Dual Bioorthogonal Labeling of the Amyloid-β Protein Precursor Facilitates Simultaneous Visualization of the Protein and Its Cleavage Products.
van Husen LS, Schedin-Weiss S, Trung MN, ..., Elsässer SJ, Tjernberg LO
J. Alzheimers Dis. 72 (2) 537-548 [2019-10-15; online 2019-10-15]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
EvoChromo: towards a synthesis of chromatin biology and evolution.
Drinnenberg IA, Berger F, Elsässer SJ, ..., Warnecke T, Wolfe KH
Development 146 (19) - [2019-09-26; online 2019-09-26]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells.
Kumar B, Elsässer SJ
Cell Reports 28 (12) 3274-3284.e5 [2019-09-17; online 2019-09-19]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Methanomethylophilus alvus Mx1201 Provides Basis for Mutual Orthogonal Pyrrolysyl tRNA/Aminoacyl-tRNA Synthetase Pairs in Mammalian Cells.
Meineke B, Heimgärtner J, Lafranchi L, Elsässer SJ
ACS chemical biology 13 (11) 3087-3096 [2018-11-16; online 2018-10-12]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Generation of Stable Amber Suppression Cell Lines
Elsässer SJ
Methods in molecular biology (Clifton, N.J.) 1728 (-) 237-245 [2018-00-00; online 2018-02-06]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Evolution of epigenetic chromatin states
Yung PYK, Elsässer SJ
Current Opinion in Chemical Biology 41 (-) 36-42 [2017-12-00; online 2017-12-00]
Affiliated researcher SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Biodiversity, drug discovery, and the future of global health: Introducing the biodiversity to biomedicine consortium, a call to action.
Neergheen-Bhujun V, Awan AT, Baran Y, ..., Pešić M, Kagansky A
Journal of global health 7 (2) 020304 [2017-12-00; online 2018-01-06]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Elsässer et al. reply.
Elsässer SJ, Noh KM, Diaz N, Allis CD, Banaszynski LA
Nature 548 (7665) E7-E9 [2017-08-02; online 2017-08-05]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Genetic code expansion in stable cell lines enables encoded chromatin modification.
Elsässer SJ, Ernst RJ, Walker OS, Chin JW
Nat. Methods 13 (2) 158-164 [2016-02-00; online 2016-01-04]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes.
Walker OS, Elsässer SJ, Mahesh M, ..., Balasubramanian S, Chin JW
Journal of the American Chemical Society 138 (3) 718-721 [2016-01-27; online 2016-01-12]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Critical Role of Histone Turnover in Neuronal Transcription and Plasticity.
Maze I, Wenderski W, Noh KM, ..., Molina H, Allis CD
Neuron 87 (1) 77-94 [2015-07-01; online 2015-07-04]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells.
Elsässer SJ, Noh KM, Diaz N, Allis CD, Banaszynski LA
Nature 522 (7555) 240-244 [2015-06-11; online 2015-05-04]
Affiliated researcher SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1
Schmied WH, Elsässer SJ, Uttamapinant C, Chin JW
J. Am. Chem. Soc. 136 (44) 15577-15583 [2014-11-05; online 2014-10-28]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal
Elliott TS, Townsley FM, Bianco A, ..., Lilley KS, Chin JW
Nat Biotechnol 32 (5) 465-472 [2014-05-00; online 2014-04-13]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
DAXX co-folds with H3.3/H4 using high local stability conferred by the H3.3 variant recognition residues
DeNizio JE, Elsässer SJ, Black BE
Nucleic Acids Res. 42 (7) 4318-4331 [2014-04-00; online 2014-01-31]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Genetic Encoding of Photocaged Cysteine Allows Photoactivation of TEV Protease in Live Mammalian Cells
Nguyen DP, Mahesh M, Elsässer SJ, ..., Uttamapinant C, Chin JW
J. Am. Chem. Soc. 136 (6) 2240-2243 [2014-02-12; online 2014-01-30]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Hira-Dependent Histone H3.3 Deposition Facilitates PRC2 Recruitment at Developmental Loci in ES Cells
Banaszynski LA, Wen D, Dewell S, ..., Zheng D, Allis CD
Cell 155 (1) 107-120 [2013-09-00; online 2013-09-00]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
A common structural theme in histone chaperones mimics interhistone contacts.
Elsässer SJ
Trends Biochem. Sci. 38 (7) 333-336 [2013-07-00; online 2013-06-26]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
DAXX envelops a histone H3.3–H4 dimer for H3.3-specific recognition
Elsässer SJ, Huang H, Lewis PW, ..., Allis CD, Patel DJ
Nature 491 (7425) 560-565 [2012-11-00; online 2012-10-17]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events
Liokatis S, Stützer A, Elsässer SJ, ..., Fischle W, Selenko P
Nat Struct Mol Biol 19 (8) 819-823 [2012-08-00; online 2012-07-15]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Towards a mechanism for histone chaperones
Elsässer SJ, D'Arcy S
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1819 (3-4) 211-221 [2012-03-00; online 2012-03-00]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Cancer. New epigenetic drivers of cancers.
Elsässer SJ, Allis CD, Lewis PW
Science (New York, N.Y.) 331 (6021) 1145-1146 [2011-03-04; online 2011-03-10]
SciLifeLab Fellow Simon Elsässer
SciLifeLab Data Centre
Publications 9.5.1