Adil Mardinoglu

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SciLifeLab Fellow since 2015.

Primary: Shown in the list of current labels.

Year 2026

PubMed DOI Crossref
Microbial collagenase activity is linked to oral-gut translocation in advanced chronic liver disease.
Jin S, Cenier A, Wetzel D, ..., Patel VC, Schirmer M
Nat. Microbiol 11 (1) 211-227 [2026-01-00; online 2025-12-29]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

Year 2025

PubMed DOI Crossref
A human pan-disease blood atlas of the circulating proteome.
Álvez MB, Bergström S, Kenrick J, ..., Edfors F, Uhlén M
Science (New York, N.Y.) 390 (6779) eadx2678 [2025-12-18; online 2025-12-18]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
OncoRisk: A state-of-the-art Web Server for bridging the oncogenic databases and pan-cancer cohorts to the translational oncology
Mardinoglu A, Song X, Green E, ..., Uhlén M, Zhang C
- - (-) - [2025-11-26; online 2025-11-26]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Depression is an independent risk factor for stroke reccurence and cognitive impairment in stroke patients.
Cankaya S, Safa SS, Karakus A, ..., Kumral E, Yulug B
Transl Psychiatry 15 (1) 492 [2025-11-21; online 2025-11-21]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Noscapine-bile acid hybrids as novel anticancer agents.
Babanezhad Harikandei K, Salehi P, Hasanpour Z, ..., Asghari SM, Mardinoglu A
RSC Med Chem 16 (11) 5511-5533 [2025-11-13; online 2025-08-29]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Targeting the parietal memory network with tDCS in MCI: study protocol for a randomized controlled trial.
Cankaya S, Akturk A, Karakus A, ..., Mardinoglu A, Yulug B
Front. Hum. Neurosci. 19 (-) 1661790 [2025-11-10; online 2025-11-10]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Targeting PKLR and lipogenic enzymes through JNK inhibition to develop a therapeutic strategy for MASLD and MASH
Mardinoglu A, Kim W, Li M, ..., Zhang C, Turkez H
- - (-) - [2025-09-25; online 2025-09-25]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Unravelling the Complexity of Sarcopenia Through a Systems Biology Approach.
Ceyhan AB, Altay O, Zhang C, ..., Turkez H, Mardinoglu A
Int J Mol Sci 26 (17) - [2025-09-02; online 2025-09-02]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Subjective cognitive decline in major depressive patients is associated with altered entropy and connectivity changes of temporal and insular region.
Yulug B, Yalcinkaya A, Safa SS, ..., Hanoglu L, Mardinoglu A
Transl Psychiatry 15 (1) 335 [2025-09-01; online 2025-09-01]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Longitudinal big biological data in the AI era.
Mardinoglu A, Turkez H, Shong M, ..., Hood L, Uhlen M
Mol Syst Biol 21 (9) 1147-1165 [2025-09-00; online 2025-08-05]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Anticancer effects and mechanisms of Pulsatilla chinensis, Bupleurum chinense and Polyporus umbellatus on human lung carcinoma and hepatoma cells.
Li M, Kim W, Jin H, ..., Zhang C, Mardinoglu A
Comput Struct Biotechnol J 27 (-) 3066-3078 [2025-07-13; online 2025-07-13]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Multi-Omics biological embeddings for ML-models
Otte LB, Hogstrand C, Mardinoglu A, Guo M
- 4 (-) 2316-2321 [2025-07-01; online 2025-07-01]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Systematically identification of survival-associated eQTLs in a Japanese kidney cancer cohort.
Song X, Jin H, Li X, ..., Zhang C, Mardinoglu A
PLoS Genet 21 (7) e1011770 [2025-07-00; online 2025-07-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
A resource for whole-body gene expression map of human tissues based on integration of single cell and bulk transcriptomics.
Shi M, Méar L, Karlsson M, ..., Uhlén M, Zhang C
Genome Biol. 26 (1) 152 [2025-06-03; online 2025-06-03]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Extensively acquired antimicrobial-resistant bacteria restructure the individual microbial community in post-antibiotic conditions.
Baek JW, Lim S, Park N, ..., Koh A, Lee S
NPJ Biofilms Microbiomes 11 (1) 78 [2025-05-14; online 2025-05-14]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Synthesis of novel tetrahydrobenzo[b]thiophene-3-carbonitrile (THBTC)-based heterocycles: Structural insights, reactivity profiles, and in-silico bioactivity studies
Sebhaoui J, Ashraf S, Iqbal S, ..., Turkez H, Mardinoglu A
Journal of Molecular Structure 1326 (-) 141110 [2025-04-00; online 2025-04-00]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Oral-gut microbiome interactions in advanced cirrhosis: characterisation of pathogenic enterotypes and salivatypes, virulence factors and antimicrobial resistance.
Lee S, Arefaine B, Begum N, ..., Shoaie S, Patel VC
J Hepatol 82 (4) 622-633 [2025-04-00; online 2024-10-22]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Host Plasma Microenvironment in Immunometabolically Impaired HIV Infection Leads to Dysregulated Monocyte Function and Synaptic Transmission Ex Vivo.
Mikaeloff F, Gelpi M, Escós A, ..., Nielsen SD, Neogi U
Adv Sci (Weinh) 12 (16) e2416453 [2025-04-00; online 2025-02-27]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Integrative proteo-transcriptomic characterization of advanced fibrosis in chronic liver disease across etiologies.
Yang H, Atak D, Yuan M, ..., Mardinoglu A, Zeybel M
Cell Rep Med 6 (2) 101935 [2025-02-18; online 2025-01-30]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Synthesis and Characterization of Memantine-Loaded Niosomes for Enhanced Alzheimer's Disease Targeting.
Turkez H, Oner S, Yıldırım OC, ..., Di Stefano A, Mardinoglu A
Pharmaceutics 17 (2) - [2025-02-17; online 2025-02-17]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats.
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
Elife 13 (-) - [2025-02-11; online 2025-02-11]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
Elife 13 (-) - [2025-02-11; online 2025-02-11]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Design, Synthesis, and Computational Evaluation of 3,4-Dihydroquinolin-2(1H)-One Analogues as Potential VEGFR2 Inhibitors in Glioblastoma Multiforme.
Buhlak S, Abad N, Akachar J, ..., Türkez H, Mardinoglu A
Pharmaceuticals (Basel, Switzerland) 18 (2) - [2025-02-08; online 2025-02-08]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
- - (-) - [2025-01-30; online 2025-01-30]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Author response: Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
- - (-) - [2025-01-30; online 2025-01-30]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Cellular and immune landscape of chronic liver diseases: insights from immunophenotyping.
Soleimani S, Albayrak O, Somay K, ..., Dayangac M, Zeybel M
Front Mol Biosci 11 (-) 1521811 [2025-01-29; online 2025-01-29]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Advancing Chronic Liver Disease Diagnoses: Targeted Proteomics for the Non-Invasive Detection of Fibrosis
Villanueva Raisman A, Kotol D, Altay O, ..., Zeybel M, Edfors F
Livers 5 (1) 2 [2025-01-14; online 2025-01-14]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Multi-omics characterization of improved cognitive functions in Parkinson's disease patients after the combined metabolic activator treatment: a randomized, double-blinded, placebo-controlled phase II trial.
Yulug B, Altay O, Li X, ..., Uhlén M, Mardinoglu A
Brain Commun 7 (1) fcae478 [2025-01-06; online 2025-01-06]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
The Human Pathology Atlas for deciphering the prognostic features of human cancers.
Yuan M, Zhang C, Von Feilitzen K, ..., Uhlén M, Mardinoglu A
EBioMedicine 111 (-) 105495 [2025-01-00; online 2024-12-10]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
PKLR-Modulating Compounds Show Promising Effects for the Treatment of Hepatocellular Carcinoma
Kim W, Jin H, Miao P, ..., Zhang C, Mardinoglu A
- - (-) - [2025-00-00; online 2025-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Multi-Omics Analysis Reveals Key Factors Associated with the Parkinson's Disease Severity
Mardinoglu A, Jin H, Meng L, ..., Zhang C, Uhlen M
- - (-) - [2025-00-00; online 2025-00-00]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

Year 2024

PubMed DOI Crossref
Identification of SPP1 + macrophages as an immune suppressor in hepatocellular carcinoma using single-cell and bulk transcriptomics.
Jin H, Kim W, Yuan M, ..., Zhang C, Mardinoglu A
Front Immunol 15 (-) 1446453 [2024-12-03; online 2024-12-03]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Targeting Alzheimer's disease with novel dual-function 3,5-diaryl-4,5-dihydro-1H-pyrazole-1-carbothioamide derivatives
Katsogiannou A, Karta D, Di Stefano A, ..., Vassiliou S, Cacciatore I
European Journal of Medicinal Chemistry Reports 12 (-) 100235 [2024-12-00; online 2024-12-00]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Novel tetrahydronaphthalen-1-yl-phenethyl ureas: synthesis and dual antibacterial-anticancer activities.
Akbaba Y, Kacı FN, Arslan ME, ..., Mardinoğlu A, Türkez H
J Enzyme Inhib Med Chem 39 (1) 2286925 [2024-12-00; online 2023-12-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Boric Acid and Borax Protect Human Lymphocytes from Oxidative Stress and Genotoxicity Induced by 3-Monochloropropane-1,2-diol.
Turkez H, Tozlu OO, Arslan ME, ..., Tatar A, Mardinoglu A
Biol Trace Elem Res 202 (11) 5006-5016 [2024-11-00; online 2024-01-13]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
187 System biology based drug repositioning approach identifies drug candidates for pancreatic ductal adenocarcinoma
Yuan M, Mardinoglu A
- - (-) A215-A215 [2024-11-00; online 2024-11-05]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Multi-omics characterization of lymphedema-induced adipose tissue resulting from breast cancer-related surgery.
Karaman S, Lehti S, Zhang C, ..., Alitalo K, Kivelä R
FASEB J. 38 (20) e70097 [2024-10-31; online 2024-10-12]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
PKLR-modulating compounds show promising effects for the treatment of hepatocellular carcinoma
Mardinoglu A, Kim W, Jin H, ..., Shi X, Zhang C
- - (-) - [2024-10-30; online 2024-10-30]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Identifying Hub Genes and Metabolic Pathways in Collagen VI-Related Dystrophies: A Roadmap to Therapeutic Intervention.
Ceyhan AB, Kaynar A, Altay O, ..., Turkez H, Mardinoglu A
Biomolecules 14 (11) - [2024-10-29; online 2024-10-29]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Synthesis, Characterization, Theoretical Studies and in Vitro Embriyotoxic, Genotoxic and Anticancer Effects of Novel Phenyl(1,4,6-Triphenyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidin-5-yl)Methanone
Akbas E, Othman KA, Çelikezen FÇ, ..., Yapca OE, Mardinoglu A
Polycyclic Aromatic Compounds 44 (9) 6284-6301 [2024-10-20; online 2023-11-03]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Multi-omics analysis reveals the key factors involved in the severity of the Alzheimer's disease.
Meng L, Jin H, Yulug B, ..., Uhlén M, Mardinoglu A
Alzheimers Res Ther 16 (1) 213 [2024-10-02; online 2024-10-02]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Unveiling the Molecular Mechanisms of Glioblastoma through an Integrated Network-Based Approach.
Kaynar A, Kim W, Ceyhan AB, ..., Shoaie S, Mardinoglu A
Biomedicines 12 (10) - [2024-10-01; online 2024-10-01]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Design and evaluation of novel inhibitors for the treatment of clear cell renal cell carcinoma.
Bouzian Y, El Hafi M, Parvizi N, ..., Turkez H, Mardinoglu A
Bioorg Chem 151 (-) 107597 [2024-10-00; online 2024-07-06]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Discovery of 2-Aryl-4-aminoquinazolin-Based LSD1 Inhibitors to Activate Immune Response in Gastric Cancer.
Wang B, Wang SW, Zhou Y, ..., Chen XB, Dai XJ
J Med Chem 67 (18) 16165-16184 [2024-09-26; online 2024-09-12]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
- - (-) - [2024-09-12; online 2024-09-12]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Transient colonizing microbes promote gut dysbiosis and functional impairment.
Lee S, Meslier V, Bidkhori G, ..., Uhlen M, Shoaie S
NPJ Biofilms Microbiomes 10 (1) 80 [2024-09-08; online 2024-09-08]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Unveiling structural features, chemical reactivity, and bioactivity of a newly synthesized purine derivative through crystallography and computational approaches
Abad N, Buhlak S, Hajji M, ..., Turkez H, Mardinoglu A
Journal of Molecular Structure 1311 (-) 138400 [2024-09-00; online 2024-09-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Synthesis, spectroscopic characterization, DFT and molecular docking of N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl) naphthalene-1-sulfonamide derivatives
Ashraf S, Iqbal S, Sebhaoui J, ..., Turkez H, Mardinoglu A
Journal of Molecular Structure 1312 (-) 138470 [2024-09-00; online 2024-09-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Extensively acquired antimicrobial resistant bacteria restructure the individual microbial community in post-antibiotic conditions
Baek JW, Lim S, Park N, ..., Koh A, Lee S
- - (-) - [2024-08-07; online 2024-08-07]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide expression analysis in a Fabry disease human podocyte cell line.
Snanoudj S, Derambure C, Zhang C, ..., Bekri S, Tebani A
Heliyon 10 (14) e34357 [2024-07-30; online 2024-07-09]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Global compositional and functional states of the human gut microbiome in health and disease.
Lee S, Portlock T, Le Chatelier E, ..., Uhlen M, Shoaie S
Genome Res 34 (6) 967-978 [2024-07-23; online 2024-07-23]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Discovery of Cell-Permeable Allosteric Inhibitors of Liver Pyruvate Kinase: Design and Synthesis of Sulfone-Based Urolithins.
Iqbal S, Islam MZ, Ashraf S, ..., Turkez H, Mardinoglu A
Int J Mol Sci 25 (14) - [2024-07-22; online 2024-07-22]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Discovery of a Therapeutic Agent for Glioblastoma Using a Systems Biology-Based Drug Repositioning Approach.
Kaynar A, Ozcan M, Li X, ..., Shoaie S, Mardinoglu A
Int J Mol Sci 25 (14) - [2024-07-18; online 2024-07-18]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Retraction notice to "Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases" [Life Sci. 314 (2023) 121325].
Turkez H, Altay O, Yildirim S, ..., Uhlén M, Mardinoglu A
Life Sci 349 (-) 122712 [2024-07-15; online 2024-05-18]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Genome-scale metabolic network of human carotid plaque reveals the pivotal role of glutamine/glutamate metabolism in macrophage modulating plaque inflammation and vulnerability.
Jin H, Zhang C, Nagenborg J, ..., Mardinoglu A, Biessen EAL
Cardiovasc Diabetol 23 (1) 240 [2024-07-08; online 2024-07-08]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Rapid genome sequencing for critically ill infants: an inaugural pilot study from Turkey.
Guner Yilmaz B, Akgun-Dogan O, Ozdemir O, ..., Ozbek U, Alanay Y
Front Pediatr 12 (-) 1412880 [2024-07-04; online 2024-07-04]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Corrigendum to "Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning" [eBioMedicine, 2022;83:104214].
Zhang C, Shi M, Kim W, ..., Boren J, Mardinoglu A
EBioMedicine 105 (-) 105224 [2024-07-00; online 2024-06-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
The use of systems biology in treatment of metabolic diseases
Mardinoglu A
Free Radic. Biol. Med. 218 (-) 53 [2024-06-00; online 2024-06-00]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Design and synthesis of novel JNK inhibitors targeting liver pyruvate kinase for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma.
Iqbal S, Sebhaoui J, Ashraf S, ..., Turkez H, Mardinoglu A
Bioorg Chem 147 (-) 107425 [2024-06-00; online 2024-05-03]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Synthesis and Biological Evaluation of Novel Benzylidene Thiazolo Pyrimidin-3(5 )-One Derivatives
Akbas E, Othman KA, Çelikezen FÇ, ..., Yapca OE, Mardinoglu A
Polycyclic Aromatic Compounds 44 (5) 3061-3078 [2024-05-27; online 2023-07-16]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
High Resolution Crystal Structure of the Pyruvate Kinase Tetramer in Complex with the Allosteric Activator Mitapivat/AG-348
Han X, Sandalova T, Zhang C, ..., Achour A, Sun R
Crystals 14 (5) 441 [2024-05-05; online 2024-05-05]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Generation of Anterior Segment of the Eye Cells from hiPSCs in Microfluidic Platforms.
Koçak G, Uyulgan S, Polatlı E, ..., Utine CA, Güven S
Adv Biol (Weinh) 8 (5) e2400018 [2024-05-00; online 2024-04-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases.
Altay O, Yang H, Yildirim S, ..., Turkez H, Mardinoglu A
Biomedicines 12 (4) - [2024-04-22; online 2024-04-22]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Drug repositioning for immunotherapy in breast cancer using single-cell analysis.
Mohammadi E, Dashti S, Shafizade N, ..., Mardinoglu A, Sekhavati MH
NPJ Syst Biol Appl 10 (1) 37 [2024-04-08; online 2024-04-08]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Sulfone-based human liver pyruvate kinase inhibitors - Design, synthesis and in vitro bioactivity.
Matić J, Akladios F, Battisti UM, ..., Uhlen M, Grøtli M
Eur J Med Chem 269 (-) 116306 [2024-04-05; online 2024-03-05]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
A comparison between different human hepatocyte models reveals profound differences in net glucose production, lipid composition and metabolism in vitro.
Bonanini F, Singh M, Yang H, ..., Mardinoglu A, Hankemeier T
Exp. Cell Res. 437 (1) 114008 [2024-04-01; online 2024-03-16]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
In Vitro Cytotoxic, Genotoxic, Embryotoxic and Oxidative Damage Potentials by Empagliflozin
Kenan Cadirci , Turkez H, Tozlu OO, ..., Emsen B, Mardinoglu A
Biol Bull Russ Acad Sci 51 (2) 243-250 [2024-04-00; online 2024-02-09]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Remodeling of the human skeletal muscle proteome found after long-term endurance training but not after strength training.
Emanuelsson EB, Arif M, Reitzner SM, ..., Sundberg CJ, Chapman MA
iScience 27 (1) 108638 [2024-01-19; online 2023-12-05]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Tuning of CHO secretional machinery improve activity of secreted therapeutic sulfatase 150-fold.
Thalén NB, Barzadd MM, Lundqvist M, ..., Sandegren A, Rockberg J
Metab. Eng. 81 (-) 157-166 [2024-01-00; online 2023-12-09]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Molecular profiling of high-level athlete skeletal muscle after acute endurance or resistance exercise - A systems biology approach.
Reitzner SM, Emanuelsson EB, Arif M, ..., Chapman MA, Sundberg CJ
Mol Metab 79 (-) 101857 [2024-01-00; online 2023-12-21]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Multi-Tissue Network Analysis Reveals the Effect of JNK Inhibition on Dietary Sucrose-Induced Metabolic Dysfunction in Rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
- - (-) - [2024-00-00; online 2024-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Integrative Proteo-Transcriptomic Characterization of Advanced Fibrosis in Chronic Liver Disease Across Etiologies
Yang H, Atak D, Yuan M, ..., Mardinoglu A, Zeybel M
- - (-) - [2024-00-00; online 2024-00-00]
Adil Mardinoglu SciLifeLab Fellow

Year 2023

PubMed DOI Crossref
Drug Synergism of Anticancer Action in Combination with Favipiravir and Paclitaxel on Neuroblastoma Cells.
Turkez H, Arslan ME, Selvitopi H, ..., Oner S, Mardinoglu A
Medicina (Kaunas) 60 (1) - [2023-12-30; online 2023-12-30]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Multi-omics network analysis on samples from sequential biopsies reveals vital role of proliferation arrest for Macrosteatosis related graft failure in rats after liver transplantation.
Liu Z, Wang W, Li X, ..., Mardinoglu A, Zheng S
Genomics 115 (6) 110748 [2023-11-19; online 2023-11-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Novel styryl-thiazole hybrids as potential anti-Alzheimer's agents.
Gouleni N, Di Rienzo A, Yılmaz A, ..., Vassiliou S, Cacciatore I
RSC Med Chem 14 (11) 2315-2326 [2023-11-15; online 2023-09-21]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Anticancer Potential of Novel Cinnamoyl Derivatives against U87MG and SHSY-5Y Cell Lines.
Gouleni N, Di Rienzo A, Oner S, ..., Vassiliou S, Cacciatore I
Anticancer Agents Med Chem 24 (1) 39-49 [2023-11-14; online 2023-11-14]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Multi-omics characterization of lymphedema-induced adipose tissue from breast cancer patients
Karaman S, Lehti S, Zhang C, ..., Alitalo K, Kivelä R
- - (-) - [2023-11-06; online 2023-11-06]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Open MoA: revealing the mechanism of action (MoA) based on network topology and hierarchy.
Liao X, Ozcan M, Shi M, ..., Mardinoglu A, Zhang C
Bioinformatics 39 (11) - [2023-11-01; online 2023-11-06]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Characterization of an in vitro steatosis model simulating activated de novo lipogenesis in MAFLD patients.
Kim W, Li M, Jin H, ..., Zhang C, Mardinoglu A
iScience 26 (10) 107727 [2023-10-20; online 2023-08-25]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Systems-level temporal immune-metabolic profile in Crimean-Congo hemorrhagic fever virus infection.
Ambikan AT, Elaldi N, Svensson-Akusjärvi S, ..., Mirazimi A, Neogi U
Proc. Natl. Acad. Sci. U.S.A. 120 (37) e2304722120 [2023-09-12; online 2023-09-05]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
EGb 761 reduces Ca2+ influx and apoptosis after pentylenetetrazole treatment in a neuroblastoma cell line.
Ovey IS, Ozsimsek A, Velioglu HA, ..., Mardinoglu A, Yulug B
Front. Cell. Neurosci. 17 (-) 1195303 [2023-09-07; online 2023-09-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Systematic transcriptional analysis of human cell lines for gene expression landscape and tumor representation.
Jin H, Zhang C, Zwahlen M, ..., Uhlén M, Mardinoglu A
Nat Commun 14 (1) 5417 [2023-09-05; online 2023-09-05]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Infection with COVID-19 is no longer a public emergency: But what about degenerative dementia?
Yulug B, Ayyıldız B, Ayyıldız S, ..., Velioglu HA, Mardinoglu A
J Med Virol 95 (9) e29072 [2023-09-00; online 2023-09-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Tissue pleiotropic effect of biotin and prebiotic supplementation in established obesity.
Voland L, Yuan M, Lecoutre S, ..., Soula H, Clément K
Am. J. Physiol. Endocrinol. Metab. - (-) - [2023-08-30; online 2023-08-30]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
The acute effect of different NAD+ precursors included in the combined metabolic activators.
Li X, Yang H, Jin H, ..., Borén J, Mardinoglu A
Free Radic. Biol. Med. 205 (-) 77-89 [2023-08-20; online 2023-06-02]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Pathogenic entero- and salivatypes harbour changes in microbiome virulence and antimicrobial resistance genes with increasing chronic liver disease severity
Lee S, Arefaine B, Begum N, ..., Shoaie S, Patel VC
- - (-) - [2023-08-07; online 2023-08-07]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Longitudinal metabolomics analysis reveals the acute effect of cysteine and NAC included in the combined metabolic activators.
Yang H, Li X, Jin H, ..., Borén J, Mardinoglu A
Free Radic. Biol. Med. 204 (-) 347-358 [2023-08-01; online 2023-05-26]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Oxidative, Genotoxic and Cytotoxic Damage Potential of Novel Borenium and Borinium Compounds
Oguzkan SB, Turkez H, Ugras HI, Tatar A, Mardinoglu A
Inorganics 11 (8) 324 [2023-07-31; online 2023-07-31]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Next generation pan-cancer blood proteome profiling using proximity extension assay.
Álvez MB, Edfors F, von Feilitzen K, ..., Fagerberg L, Uhlén M
Nat Commun 14 (1) 4308 [2023-07-18; online 2023-07-18]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Cardiomyocyte-specific PCSK9 deficiency compromises mitochondrial bioenergetics and heart function.
Laudette M, Lindbom M, Arif M, ..., Levin MC, Borén J
Cardiovasc Res 119 (7) 1537-1552 [2023-07-04; online 2023-03-08]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Drug repositioning targeting glutaminase reveals drug candidates for the treatment of Alzheimer's disease patients.
Bayraktar A, Li X, Kim W, ..., Shoaie S, Mardinoglu A
J Transl Med 21 (1) 332 [2023-05-20; online 2023-05-20]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Revisiting the role of serine metabolism in hepatic lipogenesis.
Yang H, Zhang C, Turkez H, ..., Boren J, Mardinoglu A
Nat Metab 5 (5) 760-761 [2023-05-00; online 2023-05-11]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Discovery of drug targets and therapeutic agents based on drug repositioning to treat lung adenocarcinoma.
Graves OK, Kim W, Özcan M, ..., Mardinoglu A, Li X
Biomed. Pharmacother. 161 (-) 114486 [2023-05-00; online 2023-03-10]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Exploration of Novel Urolithin C Derivatives as Non-Competitive Inhibitors of Liver Pyruvate Kinase.
Battisti UM, Monjas L, Akladios F, ..., Mardinoğlu A, Grøtli M
Pharmaceuticals (Basel, Switzerland) 16 (5) - [2023-04-28; online 2023-04-28]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia.
Rutten MGS, Lei Y, Hoogerland JH, ..., van de Sluis B, Oosterveer MH
Cancer Metab 11 (1) 5 [2023-04-21; online 2023-04-21]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Molecular profiling of high-level athlete skeletal muscle after acute exercise – a systems biology approach
Reitzner SM, Emanuelsson EB, Arif M, ..., Chapman MA, Sundberg CJ
- - (-) - [2023-04-11; online 2023-04-11]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Costunolide and Parthenolide Ameliorate MPP+ Induced Apoptosis in the Cellular Parkinson's Disease Model.
Arslan ME, Türkez H, Sevim Y, ..., Öner S, Mardinoğlu A
Cells 12 (7) - [2023-03-24; online 2023-03-24]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
standard-GEM: standardization of open-source genome-scale metabolic models
Anton M, Almaas E, Benfeitas R, ..., Zeidan AA, Kerkhoven EJ
- - (-) - [2023-03-23; online 2023-03-23]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
TASL Practice Guidance on the Clinical Assessment and Management of Patients with Nonalcoholic Fatty Liver Disease.
Yilmaz Y, Zeybel M, Adali G, ..., Kaymakoglu S, Gunsar F
Hepatol Forum 4 (Suppl 1) 1-32 [2023-03-15; online 2023-03-15]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection.
Mikaeloff F, Gelpi M, Benfeitas R, ..., Nielsen SD, Neogi U
Elife 12 (-) - [2023-02-16; online 2023-02-16]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases.
Turkez H, Altay O, Yildirim S, ..., Uhlén M, Mardinoglu A
Life Sci 314 (-) 121325 [2023-02-01; online 2022-12-26]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: a randomised, double-blinded, placebo-controlled phase-II trial.
Yulug B, Altay O, Li X, ..., Uhlén M, Mardinoglu A
Transl Neurodegener 12 (1) 4 [2023-01-26; online 2023-01-26]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase.
Battisti UM, Gao C, Akladios F, ..., Mardinoglu A, Grøtli M
Nutrients 15 (3) - [2023-01-22; online 2023-01-22]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Drug repositioning for immunotherapy in breast cancer using single-cell analysis
Mohammadi E, Jin H, Zhang C, ..., Mardinoglu A, Sekhavati MH
- - (-) - [2023-01-05; online 2023-01-05]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Author response: Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection
Mikaeloff F, Gelpi M, Benfeitas R, ..., Nielsen SD, Neogi U
- - (-) - [2023-01-04; online 2023-01-04]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase.
Battisti UM, Gao C, Nilsson O, ..., Mardinoglu A, Grøtli M
Chembiochem 24 (1) e202200339 [2023-01-03; online 2022-11-09]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Cover Feature: Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase (ChemBioChem 1/2023)
Battisti UM, Gao C, Nilsson O, ..., Mardinoglu A, Grøtli M
Chembiochem 24 (1) - [2023-01-03; online 2022-12-14]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
The Role of Willpower in Major Depressive Disorder: An fMRI Study
Yulug B, Uygur B, Sayman D, ..., Velioglu HA, Mardinoglu A
- - (-) - [2023-00-00; online 2023-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Impaired Immuno-Metabolic Homeostasis and Microenvironmental Influence on Neuropsychiatric Risk in Treated HIV Infection
Mikaeloff F, Gelpi M, Escós A, ..., Nielsen SD, Neogi U
- - (-) - [2023-00-00; online 2023-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Genome-Wide Annotation of the Human Protein-Coding Genes Using Co-Expression Clustering
Bueno Álvez M, Karlsson M, Shi M, ..., Fagerberg L, Lindskog C
- - (-) - [2023-00-00; online 2023-00-00]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
DOI Crossref
Ckap4 is Identified as a Therapeutic Target for the Treatment of Kidney Fibrosis
Shi M, Xu P, Kim W, ..., Mardinoglu A, Zhang C
- - (-) - [2023-00-00; online 2023-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Characterization of an <i>in vitro</i> Steatosis Model for Modelling the Activated <i>de novo</i> Lipogenesis in MAFLD Patients
Kim W, Li M, Jin H, ..., Zhang C, Mardinoglu A
- - (-) - [2023-00-00; online 2023-00-00]
Adil Mardinoglu SciLifeLab Fellow

Year 2022

PubMed DOI Crossref
Lipoic Acid Conjugated Boron Hybrids Enhance Wound Healing and Antimicrobial Processes.
Türkez H, Yıldırım ÖÇ, Öner S, ..., Yapça ÖE, Mardinoğlu A
Pharmaceutics 15 (1) - [2022-12-31; online 2022-12-31]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
In Vitro Transcriptome Analysis of Cobalt Boride Nanoparticles on Human Pulmonary Alveolar Cells.
Arslan ME, Tatar A, Yıldırım ÖÇ, ..., Mardinoğlu A, Türkez H
Materials (Basel) 15 (23) - [2022-12-06; online 2022-12-06]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Development of l-Dopa-containing diketopiperazines as blood-brain barrier shuttle.
Cornacchia C, Marinelli L, Di Rienzo A, ..., Di Stefano A, Cacciatore I
Eur J Med Chem 243 (-) 114746 [2022-12-05; online 2022-09-08]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Editorial: Application of systems biology in molecular characterization and diagnosis of cancer, Volume II.
Wei Y, Zhang C, Mardinoglu A, Zhang P
Front Mol Biosci 9 (-) 1089463 [2022-11-25; online 2022-11-25]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Toxicity of Glycyl-l-Prolyl-l-Glutamate Pseudotripeptides: Cytotoxic, Oxidative, Genotoxic, and Embryotoxic Perspectives.
Turkez H, Ozdemir Tozlu O, Tatar A, ..., Di Stefano A, Mardinoglu A
J Toxicol 2022 (-) 3775194 [2022-11-19; online 2022-11-19]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Drug repositioning for immunotherapy in breast cancer using single-cell and spatial transcriptomics analysis
Mohammadi E, Jin H, Zhang C, ..., Mardinoglu A, Sekhavati MH
- - (-) - [2022-11-18; online 2022-11-18]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Next generation pan-cancer blood proteome profiling using proximity extension assay
Uhlen M, Álvez MB, Edfors F, ..., Pontén F, Fagerberg L
- - (-) - [2022-11-01; online 2022-11-01]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
In Vitro and In Vivo Neuroprotective Effects of Sarcosine.
Tanas A, Tozlu ÖÖ, Gezmiş T, ..., Mardinoğlu A, Türkez H
Biomed Res Int 2022 (-) 5467498 [2022-10-15; online 2022-10-15]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Chronic hyperinsulinemia promotes human hepatocyte senescence.
Baboota RK, Spinelli R, Erlandsson MC, ..., Kahn CR, Smith U
Mol Metab 64 (-) 101558 [2022-10-00; online 2022-07-21]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Assessment of the neuroprotective potential of d-cycloserine and l-serine in aluminum chloride-induced experimental models of Alzheimer's disease: In vivo and in vitro studies.
Tozlu ÖÖ, Türkez H, Okkay U, ..., Hacımüftüoğlu A, Mardinoğlu A
Front Nutr 9 (-) 981889 [2022-09-08; online 2022-09-08]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning.
Zhang C, Shi M, Kim W, ..., Boren J, Mardinoglu A
EBioMedicine 83 (-) 104214 [2022-09-00; online 2022-08-18]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity.
Ambikan AT, Yang H, Krishnan S, ..., Benfeitas R, Neogi U
Cell Syst 13 (8) 665-681.e4 [2022-08-17; online 2022-07-08]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Ameliorative Effects by Hexagonal Boron Nitride Nanoparticles against Beta Amyloid Induced Neurotoxicity.
Aydin N, Turkez H, Tozlu OO, ..., Di Stefano A, Mardinoglu A
Nanomaterials (Basel) 12 (15) - [2022-08-05; online 2022-08-05]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Genome-wide single cell annotation of the human protein-coding genes
Karlsson M, Álvez MB, Shi M, ..., Fagerberg L, Uhlén M
- - (-) - [2022-08-04; online 2022-08-04]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
BMP4 and Gremlin 1 regulate hepatic cell senescence during clinical progression of NAFLD/NASH.
Baboota RK, Rawshani A, Bonnet L, ..., Blüher M, Smith U
Nat Metab 4 (8) 1007-1021 [2022-08-00; online 2022-08-22]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Author Correction: Spatiotemporal dissection of the cell cycle with single-cell proteogenomics.
Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan DP, Lundberg E
Nature 608 (7924) E32 [2022-08-00; online 2022-08-06]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Boron Compounds Exhibit Protective Effects against Aluminum-Induced Neurotoxicity and Genotoxicity: In Vitro and In Vivo Study.
Turkez H, Yıldırım S, Sahin E, ..., Saruhan F, Mardinoglu A
Toxics 10 (8) - [2022-07-28; online 2022-07-28]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Boron Nitride Nanoparticles Loaded with a Boron-Based Hybrid as a Promising Drug Carrier System for Alzheimer's Disease Treatment.
Yıldırım ÖÇ, Arslan ME, Öner S, ..., Mardinoglu A, Turkez H
Int J Mol Sci 23 (15) - [2022-07-26; online 2022-07-26]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Genome-scale metabolic modelling of the human gut microbiome reveals changes in the glyoxylate and dicarboxylate metabolism in metabolic disorders.
Proffitt C, Bidkhori G, Lee S, ..., Moyes DL, Shoaie S
iScience 25 (7) 104513 [2022-07-15; online 2022-06-02]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
MRI characterization of skeletal muscle size and fatty infiltration in long-term trained and untrained individuals.
Emanuelsson EB, Berry DB, Reitzner SM, ..., Sundberg CJ, Chapman MA
Physiol Rep 10 (14) e15398 [2022-07-00; online 2022-07-21]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Hexokinase 1b is a novel target for Non–small-cell lung cancer
Yozgat Y, Karakoc E, Sahin O, ..., Ozturk G, Cevher MA
- - (-) - [2022-06-30; online 2022-06-30]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Repositioning of Anti-Inflammatory Drugs for the Treatment of Cervical Cancer Sub-Types.
Kori M, Arga KY, Mardinoglu A, Turanli B
Front. Pharmacol. 13 (-) 884548 [2022-06-13; online 2022-06-13]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection
Mikaeloff F, Gelpi M, Benfeitas R, ..., Nielsen SD, Neogi U
- - (-) - [2022-06-13; online 2022-06-13]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Machine Learning Analysis Reveals Biomarkers for the Detection of Neurological Diseases.
Lam S, Arif M, Song X, Uhlén M, Mardinoglu A
Front Mol Neurosci 15 (-) 889728 [2022-05-31; online 2022-05-31]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Recent Progress and Future Direction for the Application of Multiomics Data in Clinical Liver Transplantation.
Liu Z, Xu J, Que S, ..., Mardinoglu A, Zheng S
J Clin Transl Hepatol 10 (2) 363-373 [2022-04-28; online 2022-01-04]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase.
Nain-Perez A, Foller Füchtbauer A, Håversen L, ..., Uhlen M, Grøtli M
Eur J Med Chem 234 (-) 114270 [2022-04-15; online 2022-03-08]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Prediction of drug candidates for clear cell renal cell carcinoma using a systems biology-based drug repositioning approach.
Li X, Shong K, Kim W, ..., Zhang C, Mardinoglu A
EBioMedicine 78 (-) 103963 [2022-04-00; online 2022-03-25]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Multiomics Analysis Reveals the Impact of Microbiota on Host Metabolism in Hepatic Steatosis.
Zeybel M, Arif M, Li X, ..., Borén J, Mardinoglu A
Adv Sci (Weinh) 9 (11) e2104373 [2022-04-00; online 2022-02-07]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target.
Smati S, Polizzi A, Fougerat A, ..., Gourdy P, Guillou H
Gut 71 (4) 807-821 [2022-04-00; online 2021-04-26]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Molecular Genetics and Cytotoxic Responses to Titanium Diboride and Zinc Borate Nanoparticles on Cultured Human Primary Alveolar Epithelial Cells.
Türkez H, Arslan ME, Tatar A, ..., Tatar A, Mardinoglu A
Materials (Basel) 15 (7) - [2022-03-22; online 2022-03-22]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
A Gene Co-Expression Network-Based Drug Repositioning Approach Identifies Candidates for Treatment of Hepatocellular Carcinoma.
Yuan M, Shong K, Li X, ..., Zhang C, Mardinoglu A
Cancers (Basel) 14 (6) - [2022-03-19; online 2022-03-19]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Correction to: Toxicogenomics directory of chemically exposed human hepatocytes.
Grinberg M, Stöber RM, Edlund K, ..., Rahnenführer J, Hengstler JG
Arch. Toxicol. 96 (3) 945-946 [2022-03-00; online 2022-02-01]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Stratification of the Gut Microbiota Composition Landscape across the Alzheimer's Disease Continuum in a Turkish Cohort.
Yıldırım S, Nalbantoğlu ÖU, Bayraktar A, ..., Köseoğlu E, Hanoğlu L
mSystems 7 (1) e0000422 [2022-02-22; online 2022-02-08]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning
Zhang C, Shi M, Kim W, ..., Boren J, Mardinoglu A
- - (-) - [2022-02-17; online 2022-02-17]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Machine learning analysis reveals biomarkers for the detection of neurodegenerative diseases
Lam S, Arif M, Song X, Uhlen M, Mardinoglu A
- - (-) - [2022-02-15; online 2022-02-15]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide annotation of protein-coding genes in pig.
Karlsson M, Sjöstedt E, Oksvold P, ..., Luo Y, Uhlen M
BMC Biol. 20 (1) 25 [2022-01-25; online 2022-01-25]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Improvement of the performance of anticancer peptides using a drug repositioning pipeline.
Mohammadi E, Tahmoorespur M, Benfeitas R, ..., Mardinoglu A, Sekhavati MH
Biotechnol J 17 (1) e2100417 [2022-01-00; online 2021-11-14]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Transient Colonising Microbes Promote Gut Dysbiosis and Disease Pathology
Lee S, Meslier V, Bidkhori G, ..., Uhlen M, Shoaie S
- - (-) - [2022-00-00; online 2022-00-00]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Development of L-Dopa-Containing Diketopiperazines as Blood-Brain Barrier Shuttle
Cornacchia C, Marinelli L, Di Rienzo A, ..., Di Stefano A, Cacciatore I
- - (-) - [2022-00-00; online 2022-00-00]
Adil Mardinoglu SciLifeLab Fellow

Year 2021

PubMed DOI Crossref
Therapeutic Potential of Ferulic Acid in Alzheimer's Disease.
Turkez H, Arslan ME, Barboza JN, ..., de Sousa DP, Mardinoğlu A
Curr Drug Deliv 19 (8) 860-873 [2021-12-30; online 2021-12-30]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Systems Biology Approaches to Decipher the Underlying Molecular Mechanisms of Glioblastoma Multiforme.
Kaynar A, Altay O, Li X, ..., Shoaie S, Mardinoglu A
Int J Mol Sci 22 (24) 13213 [2021-12-08; online 2021-12-08]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Next generation plasma proteome profiling of COVID-19 patients with mild to moderate symptoms.
Zhong W, Altay O, Arif M, ..., Uhlen M, Fagerberg L
EBioMedicine 74 (-) 103723 [2021-12-00; online 2021-11-27]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
In vitro transcriptome response to propolis in differentiated SH-SY5Y neurons.
Turkez H, Arslan ME, Yilmaz A, ..., Abd El-Aty AM, Mardinoglu A
J Food Biochem 45 (12) e13990 [2021-12-00; online 2021-11-03]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
A network-based approach reveals the dysregulated transcriptional regulation in non-alcoholic fatty liver disease.
Yang H, Arif M, Yuan M, ..., Zhang C, Mardinoglu A
iScience 24 (11) 103222 [2021-11-19; online 2021-10-05]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Boron-based hybrids as novel scaffolds for the development of drugs with neuroprotective properties.
Cacciatore I, Turkez H, Di Rienzo A, ..., Mardinoglu A, Di Stefano A
RSC Med Chem 12 (11) 1944-1949 [2021-11-17; online 2021-08-13]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Glucosylceramide synthase deficiency in the heart compromises β1-adrenergic receptor trafficking.
Andersson L, Cinato M, Mardani I, ..., Borén J, Levin MC
Eur. Heart J. 42 (43) 4481-4492 [2021-11-14; online 2021-07-24]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
GutMicroNet: an interactive platform for gut microbiome interaction exploration
Arif M, Portlock T, Güngör C, ..., Mardinoglu A, Shoaie S
- - (-) - [2021-11-11; online 2021-11-11]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Safety and Efficacy Assessments to Take Antioxidants in Glioblastoma Therapy: From In Vitro Experiences to Animal and Clinical Studies.
Turkez H, Tozlu OO, Arslan ME, Mardinoglu A
Neurochem Int 150 (-) 105168 [2021-11-00; online 2021-08-25]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Stratification of the Gut Microbiota Composition Landscape Across the Alzheimer’s Disease Continuum in a Turkish Cohort
Yıldırım S, Nalbantoğlu ÖU, Bayraktar A, ..., Köseoğlu E, Hanoğlu L
- - (-) - [2021-10-30; online 2021-10-30]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Revealing the Molecular Mechanisms of Alzheimer's Disease Based on Network Analysis.
Bayraktar A, Lam S, Altay O, ..., Shoaie S, Mardinoglu A
Int J Mol Sci 22 (21) 11556 [2021-10-26; online 2021-10-26]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
The Assessment of Selected miRNA Profile in Familial Mediterranean Fever.
Kahraman CY, Egin ME, Tatar A, Turkez H, Mardinoglu A
Biomed Res Int 2021 (-) 6495700 [2021-10-13; online 2021-10-13]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Combined Metabolic Activators Decrease Liver Steatosis by Activating Mitochondrial Metabolism in Hamsters Fed with a High-Fat Diet.
Yang H, Mayneris-Perxachs J, Boqué N, ..., Mardinoglu A, Caimari A
Biomedicines 9 (10) - [2021-10-11; online 2021-10-11]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Promising potential of boron compounds against Glioblastoma: In Vitro antioxidant, anti-inflammatory and anticancer studies.
Turkez H, Arslan ME, Tatar A, Mardinoglu A
Neurochem Int 149 (-) 105137 [2021-10-00; online 2021-07-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients.
Zeybel M, Altay O, Arif M, ..., Borén J, Mardinoglu A
Mol Syst Biol 17 (10) e10459 [2021-10-00; online 2021-10-26]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer's and Parkinson's Diseases.
Lam S, Hartmann N, Benfeitas R, ..., Knight R, Mardinoglu A
Biomedicines 9 (10) - [2021-09-24; online 2021-09-24]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Multi-omics approaches for revealing the complexity of cardiovascular disease.
Doran S, Arif M, Lam S, ..., Boren J, Mardinoglu A
Brief. Bioinformatics 22 (5) - [2021-09-02; online 2021-03-17]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19.
Altay O, Arif M, Li X, ..., Uhlén M, Mardinoglu A
Adv Sci (Weinh) 8 (17) e2101222 [2021-09-00; online 2021-06-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Lysine demethylase LSD1 delivered via small extracellular vesicles promotes gastric cancer cell stemness.
Zhao LJ, Li YY, Zhang YT, ..., Zheng YC, Liu HM
EMBO Rep. 22 (8) e50922 [2021-08-04; online 2021-05-31]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Combined Metabolic Activators Improve Cognitive Functions without Altering Motor Scores in Parkinson’s Disease
Yulug B, Altay O, Li X, ..., Uhlén M, Mardinoglu A
- - (-) - [2021-08-04; online 2021-08-04]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
In vitro neuroprotective effects of farnesene sesquiterpene on alzheimer's disease model of differentiated neuroblastoma cell line.
Arslan ME, Türkez H, Mardinoğlu A
Int J Neurosci 131 (8) 745-754 [2021-08-00; online 2020-04-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Anticancer effects of novel NSAIDs derivatives on cultured human glioblastoma cells.
Özdemir Ö, Marinelli L, Cacciatore I, ..., Mardinoglu A, Turkez H
Z Naturforsch C J Biosci 76 (7-8) 329-335 [2021-07-27; online 2020-09-05]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
A network-based approach reveals the dysregulated transcriptional regulation in non-alcohol fatty liver disease
Yang H, Arif M, Yuan M, ..., Cheng Z, Mardinoglu A
- - (-) - [2021-07-26; online 2021-07-26]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning.
Li X, Kim W, Juszczak K, ..., Zhang C, Mardinoglu A
iScience 24 (7) 102722 [2021-07-23; online 2021-06-12]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Combined Metabolic Activators Improves Cognitive Functions in Alzheimer’s Disease
Yulug B, Altay O, Li X, ..., Uhlén M, Mardinoglu A
- - (-) - [2021-07-20; online 2021-07-20]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
iNetModels 2.0: an interactive visualization and database of multi-omics data.
Arif M, Zhang C, Li X, ..., Uhlen M, Mardinoglu A
Nucleic Acids Res. 49 (W1) W271-W276 [2021-07-02; online 2021-04-14]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Safety Assessments of Nickel Boride Nanoparticles on the Human Pulmonary Alveolar Cells by Using Cell Viability and Gene Expression Analyses.
Türkez H, Arslan ME, Sönmez E, ..., Açikyildiz M, Mardinoğlu A
Biol Trace Elem Res 199 (7) 2602-2611 [2021-07-00; online 2020-09-09]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
A single-cell type transcriptomics map of human tissues.
Karlsson M, Zhang C, Méar L, ..., Uhlén M, Lindskog C
Sci Adv 7 (31) - [2021-07-00; online 2021-07-28]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
DOI Crossref
Next generation plasma proteome profiling of COVID-19 patients with mild to moderate symptoms
Zhong W, Altay O, Arif M, ..., Uhlén M, Fagerberg L
- - (-) - [2021-06-21; online 2021-06-21]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
DOI Crossref
Systems analysis reveals ageing-related perturbations in retinoids and sex hormones in Alzheimer’s and Parkinson’s diseases
Lam S, Hartmann N, Benfeitas R, ..., Knight R, Mardinoglu A
- - (-) - [2021-06-10; online 2021-06-10]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Editorial: Application of Systems Biology in Molecular Characterization and Diagnosis of Cancer.
Zhang C, Wei Y, Mardinoglu A, Zhang P
Front Mol Biosci 8 (-) 668146 [2021-05-28; online 2021-05-28]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Multi-omics analysis reveals the impact of microbiota on host metabolism in hepatic steatosis
Zeybel M, Arif M, Li X, ..., Borén J, Mardinoglu A
- - (-) - [2021-05-23; online 2021-05-23]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Combined Metabolic Activators Reduces Liver Fat in Nonalcoholic Fatty Liver Disease Patients
Zeybel M, Altay O, Arif M, ..., Borén J, Mardinoglu A
- - (-) - [2021-05-23; online 2021-05-23]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Informing Pharmacokinetic Models With Physiological Data: Oral Population Modeling of L-Serine in Humans.
Bosley JR, Björnson E, Zhang C, ..., Borén J, Mardinoglu A
Front. Pharmacol. 12 (-) 643179 [2021-05-13; online 2021-05-13]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction.
Arif M, Klevstig M, Benfeitas R, ..., Mardinoglu A, Boren J
Elife 10 (-) - [2021-05-11; online 2021-05-11]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Author response: Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction
Arif M, Klevstig M, Benfeitas R, ..., Mardinoglu A, Boren J
- - (-) - [2021-04-21; online 2021-04-21]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI.
van der Kolk BW, Saari S, Lovric A, ..., Pajukanta P, Pietiläinen KH
Cell Rep Med 2 (4) 100226 [2021-04-20; online 2021-03-30]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Revealing the Metabolic Alterations during Biofilm Development of Burkholderia cenocepacia Based on Genome-Scale Metabolic Modeling.
Altay O, Zhang C, Turkez H, ..., Uhlén M, Mardinoglu A
Metabolites 11 (4) - [2021-04-05; online 2021-04-05]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Global and temporal state of the human gut microbiome in health and disease
Shoaie S, Lee S, Almeida M, ..., Ehrlich S, Uhlen M
- - (-) - [2021-04-01; online 2021-04-01]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Addressing the heterogeneity in liver diseases using biological networks.
Lam S, Doran S, Yuksel HH, ..., Uhlen M, Mardinoglu A
Brief. Bioinformatics 22 (2) 1751-1766 [2021-03-22; online 2020-03-24]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey.
Alkurt G, Murt A, Aydin Z, ..., Dinler Doganay G, Doganay HL
PLoS ONE 16 (3) e0247865 [2021-03-03; online 2021-03-03]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson's disease.
Rosario D, Bidkhori G, Lee S, ..., Mardinoglu A, Shoaie S
Cell Reports 34 (9) 108807 [2021-03-02; online 2021-03-04]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Combined Metabolic Activators decrease liver steatosis by activating mitochondrial metabolism in a Golden Syrian hamster study
Yang H, Mayneris-Perxachs J, Boqué N, ..., Mardinoglu A, Caimari A
- - (-) - [2021-02-19; online 2021-02-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Acute kidney injury leading to CKD is associated with a persistence of metabolic dysfunction and hypertriglyceridemia.
Harzandi A, Lee S, Bidkhori G, ..., Shoaie S, Sharpe CC
iScience 24 (2) 102046 [2021-02-19; online 2021-01-09]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Targeted Gene Candidates for Treatment and Early Diagnosis of Age-Related Macular Degeneration.
Cinici E, Caglar O, Arslan ME, ..., Mardinoglu A, Turkez H
Biomed Res Int 2021 (-) 6620900 [2021-02-02; online 2021-02-02]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics.
Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan DP, Lundberg E
Nature 590 (7847) 649-654 [2021-02-00; online 2021-02-24]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Glycyl-L-Prolyl-L-Glutamate Pseudotripeptides for Treatment of Alzheimer's Disease.
Turkez H, Cacciatore I, Marinelli L, ..., Di Stefano A, Mardinoglu A
Biomolecules 11 (1) - [2021-01-19; online 2021-01-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers.
Li X, Kim W, Arif M, ..., Zhang C, Mardinoglu A
Cancers (Basel) 13 (2) - [2021-01-19; online 2021-01-19]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Systems biology based drug repositioning for development of cancer therapy.
Turanli B, Altay O, Borén J, ..., Arga KY, Mardinoglu A
Semin. Cancer Biol. 68 (-) 47-58 [2021-01-00; online 2019-09-27]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Network Analyses Links Epicardial Fat Metabolism to Human Coronary Heart Disease
Doran S, Arif M, Clausen M, ..., Mardinoglu A, Boren J
- - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Multiomics Personalized Network Analyses Highlight Progressive Immune Disruption of Central Metabolism Associated with COVID-19 Severity
Ambikan AT, Yang H, Krishnan S, ..., Benfeitas R, Neogi U
- - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Genome-Scale Metabolic Modelling of the Human Gut Microbiome Reveals Changes of the Glyoxylate and Dicarboxylate Metabolism in Metabolic Disorders
Proffitt C, Bidkhori G, Lee S, ..., Moyes DL, Shoaie S
SSRN Journal - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Drug Repositioning for Clear Cell Renal Cell Carcinoma Based on Stratification of Patients
Li X, Kim W, Juszczak K, ..., Zhang C, Mardinoglu A
- - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Combined Metabolic Cofactor Supplementation Reduces Liver Fat in Nonalcoholic Fatty Liver Disease
Zeybel M, Altay O, Arif M, ..., Boren J, Mardinoglu A
SSRN Journal - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Combined Metabolic Activators Improves Cognitive Functions in Alzheimer's Disease
Yulug B, Altay O, Li X, ..., Uhlen M, Mardinoglu A
SSRN Journal - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Combined Metabolic Activators Decrease Liver Steatosis by Activating Mitochondrial Metabolism in a Golden Syrian Hamster Study
Yang H, Mayneris-Perxachs J, Boqué N, ..., Mardinoglu A, Caimari A
- - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Combined Metabolic Activators Decrease Liver Steatosis by Activating Mitochondrial Metabolism in a Golden Syrian Hamster Study
Yang H, Mayneris-Perxachs J, Boqué N, ..., Mardinoglu A, Caimari A
SSRN Journal - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
A Network-Based Approach Reveals the Dysregulated Transcriptional Regulation in Non- Alcohol Fatty Liver Disease
Yang H, Arif M, Yuan M, ..., Zhang C, Mardinoglu A
- - (-) - [2021-00-00; online 2021-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow

Year 2020

PubMed DOI Crossref
Editorial: Redox Homeostasis and Cancer.
Sinha M, Mardinoglu A, Ghose J, Singh K
Oxid Med Cell Longev 2020 (-) 5487381 [2020-12-18; online 2020-12-18]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells.
Zhan C, Bidkhori G, Schwarz H, ..., Rockberg J, Chotteau V
iScience 23 (11) 101653 [2020-11-20; online 2020-10-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Potential Anticancer Effect of Carvacrol Codrugs on Human Glioblastoma Cells.
Yazici A, Marinelli L, Cacciatore I, ..., Mardinoğlu A, Türkez H
Curr Drug Deliv 18 (3) 350-356 [2020-10-29; online 2020-10-29]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Combined Metabolic Activators accelerates recovery in mild-to-moderate COVID-19
Altay O, Arif M, Li X, ..., Uhlén M, Mardinoglu A
- - (-) - [2020-10-05; online 2020-10-05]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Body composition after allogeneic haematopoietic cell transplantation/total body irradiation in children and young people: a restricted systematic review.
Lorenc A, Hamilton-Shield J, Perry R, Stevens M, CTYA HSCT Adipose and Muscle Late Effects Working Group
J Cancer Surviv 14 (5) 624-642 [2020-10-00; online 2020-07-18]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning.
Mohammadi E, Benfeitas R, Turkez H, ..., Uhlen M, Mardinoglu A
Cancers (Basel) 12 (9) - [2020-09-21; online 2020-09-21]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Integration of molecular profiles in a longitudinal wellness profiling cohort.
Tebani A, Gummesson A, Zhong W, ..., Uhlen M, Fagerberg L
Nat Commun 11 (1) 4487 [2020-09-08; online 2020-09-08]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
DOI Crossref
Seroprevalence of Coronavirus Disease 2019 (COVID-19) Among Health Care Workers from Three Pandemic Hospitals of Turkey
Alkurt G, Murt A, Aydin Z, ..., Dinler Doganay G, Doganay L
- - (-) - [2020-08-22; online 2020-08-22]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Drug Repositioning for P-Glycoprotein Mediated Co-Expression Networks in Colorectal Cancer.
Beklen H, Gulfidan G, Arga KY, Mardinoglu A, Turanli B
Front Oncol 10 (-) 1273 [2020-08-13; online 2020-08-13]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Neuroprotective effects of boron nitride nanoparticles in the experimental Parkinson's disease model against MPP+ induced apoptosis.
Küçükdoğru R, Türkez H, Arslan ME, ..., Cacciatore I, Di Stefano A
Metab Brain Dis 35 (6) 947-957 [2020-08-00; online 2020-03-25]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Current Status of COVID-19 Therapies and Drug Repositioning Applications.
Altay O, Mohammadi E, Lam S, ..., Uhlen M, Mardinoglu A
iScience 23 (7) 101303 [2020-07-24; online 2020-06-20]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Systems Biology Approaches to Understand the Host-Microbiome Interactions in Neurodegenerative Diseases.
Rosario D, Boren J, Uhlen M, ..., Mardinoglu A, Shoaie S
Front Neurosci 14 (-) 716 [2020-07-08; online 2020-07-08]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
A systems biology approach for studying neurodegenerative diseases.
Lam S, Bayraktar A, Zhang C, ..., Uhlen M, Mardinoglu A
Drug Discov. Today 25 (7) 1146-1159 [2020-07-00; online 2020-05-19]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Skeletal Muscle Transcriptomic Comparison between Long-Term Trained and Untrained Men and Women.
Chapman MA, Arif M, Emanuelsson EB, ..., Mardinoglu A, Sundberg CJ
Cell Reports 31 (12) 107808 [2020-06-23; online 2020-06-25]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Adipose tissue morphology, imaging and metabolomics predicting cardiometabolic risk and family history of type 2 diabetes in non-obese men.
Rawshani A, Eliasson B, Rawshani A, ..., Rosengren A, Smith U
Sci Rep 10 (1) 9973 [2020-06-19; online 2020-06-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Improvement in the Current Therapies for Hepatocellular Carcinoma Using a Systems Medicine Approach.
Ozcan M, Altay O, Lam S, ..., Boren J, Mardinoglu A
Adv Biosyst 4 (6) e2000030 [2020-06-00; online 2020-04-08]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Histidyl-Proline Diketopiperazine Isomers as Multipotent Anti-Alzheimer Drug Candidates.
Turkez H, Cacciatore I, Arslan ME, ..., Di Stefano A, Mardinoglu A
Biomolecules 10 (5) 737 [2020-05-09; online 2020-05-09]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development.
Larsson I, Uhlén M, Zhang C, Mardinoglu A
Front Genet 11 (-) 381 [2020-04-17; online 2020-04-17]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
The in vitro cytotoxic, genotoxic, and oxidative damage potentials of the oral artificial sweetener aspartame on cultured human blood cells.
Çadirci K, Özdemir Tozlu Ö, Türkez H, Mardinoğlu A
Turk J Med Sci 50 (2) 448-454 [2020-04-09; online 2020-04-09]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease.
Zhang C, Bjornson E, Arif M, ..., Borén J, Mardinoglu A
Mol Syst Biol 16 (4) e9495 [2020-04-00; online 2020-04-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Publisher Correction: MEMOTE for standardized genome-scale metabolic model testing.
Lieven C, Beber ME, Olivier BG, ..., Zakhartsev M, Zhang C
Nat. Biotechnol. 38 (4) 504 [2020-04-00; online 2020-04-09]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models.
Choi MJ, Jung SB, Lee SE, ..., Yi HS, Shong M
Diabetologia 63 (4) 837-852 [2020-04-00; online 2020-01-10]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
An atlas of human metabolism.
Robinson JL, Kocabaş P, Wang H, ..., Uhlén M, Nielsen J
Sci Signal 13 (624) eaaz1482 [2020-03-24; online 2020-03-24]
Adil Mardinoglu Avlant Nilsson DDLS Fellow SciLifeLab Fellow
PubMed DOI Crossref
An atlas of the protein-coding genes in the human, pig, and mouse brain.
Sjöstedt E, Zhong W, Fagerberg L, ..., Uhlén M, Mulder J
Science (New York, N.Y.) 367 (6482) eaay5947 [2020-03-06; online 2020-03-07]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
MEMOTE for standardized genome-scale metabolic model testing.
Lieven C, Beber ME, Olivier BG, ..., Zakhartsev M, Zhang C
Nat. Biotechnol. 38 (3) 272-276 [2020-03-00; online 2020-03-04]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Classification of clear cell renal cell carcinoma based on PKM alternative splicing.
Li X, Turanli B, Juszczak K, ..., Zhang C, Mardinoglu A
Heliyon 6 (2) e03440 [2020-02-00; online 2020-02-19]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D.
Sayitoglu EC, Georgoudaki AM, Chrobok M, ..., Sutlu T, Duru AD
Front Immunol 11 (-) 40 [2020-01-28; online 2020-01-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation.
Pagoni A, Marinelli L, Di Stefano A, ..., Vassiliou S, Cacciatore I
Eur J Med Chem 186 (-) 111880 [2020-01-15; online 2019-11-12]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Discovery of Functional Alternatively Spliced <i>PKM</i> Transcripts in Human Cancers
Li X, Zhang C, Kim W, ..., Uhlen M, Mardinoglu A
- - (-) - [2020-00-00; online 2020-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Acute Kidney Injury Leading to CKD is Associated with a Persistence of Metabolic Dysfunction and Hypertriglyceridemia
Harzandi A, Bidkhori G, Lee S, ..., Shoaie S, Sharpe C
SSRN Journal - (-) - [2020-00-00; online 2020-00-00]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

Year 2019

PubMed DOI Crossref
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells.
Uhlen M, Karlsson MJ, Zhong W, ..., Fagerberg L, Brodin P
Science (New York, N.Y.) 366 (6472) eaax9198 [2019-12-20; online 2019-12-21]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
DOI Crossref
Informing Pharmacokinetic Models with Physiological Data: Oral Population Modeling of L-Serine in Humans
Bosley JR, Björnson E, Zhang C, ..., Boren J, Mardinoglu A
- - (-) - [2019-12-14; online 2019-12-14]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.
Klevstig M, Arif M, Mannila M, ..., Ehrenborg E, Borén J
J. Mol. Cell. Cardiol. 137 (-) 1-8 [2019-12-00; online 2019-09-15]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
The human secretome.
Uhlén M, Karlsson MJ, Hober A, ..., Fagerberg L, Sivertsson Å
Sci Signal 12 (609) eaaz0274 [2019-11-26; online 2019-11-26]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
DOI Crossref
Classification of clear cell renal cell carcinoma based on PKM alternative splicing
Li X, Turanli B, Juszczak K, ..., Zhang C, Mardinoglu A
- - (-) - [2019-11-12; online 2019-11-12]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Systems biology perspective for studying the gut microbiota in human physiology and liver diseases.
Altay O, Nielsen J, Uhlen M, Boren J, Mardinoglu A
EBioMedicine 49 (-) 364-373 [2019-11-00; online 2019-10-18]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer.
Cadenas C, Vosbeck S, Edlund K, ..., Marchan R, Hengstler JG
Int. J. Cancer 145 (4) 901-915 [2019-08-15; online 2019-02-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Elucidating the Reprograming of Colorectal Cancer Metabolism Using Genome-Scale Metabolic Modeling.
Zhang C, Aldrees M, Arif M, ..., Mardinoglu A, Aziz MA
Front Oncol 9 (-) 681 [2019-07-30; online 2019-07-30]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
The Potential Use of Metabolic Cofactors in Treatment of NAFLD.
Mardinoglu A, Ural D, Zeybel M, ..., Uhlén M, Borén J
Nutrients 11 (7) 1578 [2019-07-12; online 2019-07-12]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Plasma Proteomics Analysis Reveals Dysregulation of Complement Proteins and Inflammation in Acquired Obesity-A Study on Rare BMI-Discordant Monozygotic Twin Pairs.
Sahebekhtiari N, Saraswat M, Joenväärä S, ..., Renkonen R, Pietiläinen KH
Proteomics Clin Appl 13 (4) e1800173 [2019-07-00; online 2019-02-05]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
iNetModels 2.0: an interactive visualization and database of multi-omics data
Arif M, Zhang C, Li X, ..., Uhlen M, Mardinoglu A
- - (-) - [2019-06-08; online 2019-06-08]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
RMetD2: a tool for integration of relative transcriptomics data into Genome-scale metabolic models
Zhang C, Lee S, Bidkhori G, ..., Nielsen J, Mardinoglu A
- - (-) - [2019-06-06; online 2019-06-06]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Multi-Omic Data Interpretation to Repurpose Subtype Specific Drug Candidates for Breast Cancer.
Turanli B, Karagoz K, Bidkhori G, ..., Mardinoglu A, Arga KY
Front Genet 10 (-) 420 [2019-05-07; online 2019-05-07]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Discovery of functional alternatively spliced PKM transcripts in human cancers
Li X, Zhang C, Kim W, ..., Uhlen M, Mardinoglu A
- - (-) - [2019-04-18; online 2019-04-18]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes.
Harms MJ, Li Q, Lee S, ..., Spalding KL, Boucher J
Cell Reports 27 (1) 213-225.e5 [2019-04-02; online 2019-04-04]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning.
Turanli B, Zhang C, Kim W, ..., Arga KY, Mardinoglu A
EBioMedicine 42 (-) 386-396 [2019-04-00; online 2019-03-21]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Expression of PD-L1 and PD-1 in Chemoradiotherapy-Naïve Esophageal and Gastric Adenocarcinoma: Relationship With Mismatch Repair Status and Survival.
Svensson MC, Borg D, Zhang C, ..., Leandersson K, Jirström K
Front Oncol 9 (-) 136 [2019-03-13; online 2019-03-13]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function.
Liu Z, Zhang C, Lee S, ..., Boren J, Mardinoglu A
Metab. Eng. 52 (-) 263-272 [2019-03-00; online 2019-01-04]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics
Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan D, Lundberg E
- - (-) - [2019-02-07; online 2019-02-07]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysis.
Benfeitas R, Bidkhori G, Mukhopadhyay B, ..., Kunos G, Mardinoglu A
EBioMedicine 40 (-) 471-487 [2019-02-00; online 2018-12-31]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Discovery of KIRREL as a biomarker for prognostic stratification of patients with thin melanoma.
Lundgren S, Fagerström-Vahman H, Zhang C, ..., Nodin B, Jirström K
Biomark Res 7 (1) 1 [2019-01-14; online 2019-01-14]
Adil Mardinoglu SciLifeLab Fellow

Year 2018

PubMed DOI Crossref
Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes.
Bidkhori G, Benfeitas R, Klevstig M, ..., Boren J, Mardinoglu A
Proc. Natl. Acad. Sci. U.S.A. 115 (50) E11874-E11883 [2018-12-11; online 2018-11-27]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
The human secretome – the proteins secreted from human cells
Uhlen M, Tegel H, Sivertsson Å, ..., Schiavone LH, Hober S
- - (-) - [2018-11-26; online 2018-11-26]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice.
Håversen L, Sundelin JP, Mardinoglu A, ..., Levin M, Borén J
Sci Rep 8 (1) 16973 [2018-11-19; online 2018-11-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
A Network-Based Cancer Drug Discovery: From Integrated Multi-Omics Approaches to Precision Medicine.
Turanli B, Karagoz K, Gulfidan G, ..., Mardinoglu A, Arga KY
Curr. Pharm. Des. 24 (32) 3778-3790 [2018-11-07; online 2018-11-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
High Cell Density Perfusion Culture has a Maintained Exoproteome and Metabolome.
Zamani L, Lundqvist M, Zhang Y, ..., Rockberg J, Chotteau V
Biotechnol J 13 (10) e1800036 [2018-10-00; online 2018-07-13]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
ESS: A Tool for Genome-Scale Quantification of Essentiality Score for Reaction/Genes in Constraint-Based Modeling.
Zhang C, Bidkhori G, Benfeitas R, ..., Uhlén M, Mardinoglu A
Front. Physiol. 9 (-) 1355 [2018-09-28; online 2018-09-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome.
Lovric A, Granér M, Bjornson E, ..., Mardinoglu A, Boren J
Sci Rep 8 (1) 14200 [2018-09-21; online 2018-09-21]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Meta-Analysis of Adiponectin as a Biomarker for the Detection of Metabolic Syndrome.
Liu Z, Liang S, Que S, ..., Zheng S, Mardinoglu A
Front. Physiol. 9 (-) 1238 [2018-09-19; online 2018-09-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Metabolic Network-Based Identification and Prioritization of Anticancer Targets Based on Expression Data in Hepatocellular Carcinoma.
Bidkhori G, Benfeitas R, Elmas E, ..., Nielsen J, Mardinoglu A
Front. Physiol. 9 (-) 916 [2018-07-17; online 2018-07-17]
Adil Mardinoglu Affiliated researcher DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Understanding the Representative Gut Microbiota Dysbiosis in Metformin-Treated Type 2 Diabetes Patients Using Genome-Scale Metabolic Modeling.
Rosario D, Benfeitas R, Bidkhori G, ..., Shoaie S, Mardinoglu A
Front. Physiol. 9 (-) 775 [2018-06-25; online 2018-06-25]
Adil Mardinoglu Affiliated researcher Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Memote: A community driven effort towards a standardized genome-scale metabolic model test suite
Lieven C, Beber ME, Olivier BG, ..., Zakhartsev M, Zhang C
- - (-) - [2018-06-21; online 2018-06-21]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Systems biology in hepatology: approaches and applications.
Mardinoglu A, Boren J, Smith U, Uhlen M, Nielsen J
Nat Rev Gastroenterol Hepatol 15 (6) 365-377 [2018-06-00; online 2018-04-25]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Drug Repositioning for Effective Prostate Cancer Treatment.
Turanli B, Grøtli M, Boren J, ..., Arga KY, Mardinoglu A
Front. Physiol. 9 (-) 500 [2018-05-15; online 2018-05-15]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia.
Danielsson F, Fasterius E, Sullivan D, ..., Williams C, Lundberg E
Oncotarget 9 (28) 19730-19744 [2018-04-13; online 2018-04-13]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma.
Huvila J, Laajala TD, Edqvist PH, ..., Aittokallio T, Auranen A
Gynecol. Oncol. 149 (1) 173-180 [2018-04-00; online 2018-03-02]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.
Mardinoglu A, Wu H, Bjornson E, ..., Taskinen MR, Borén J
Cell Metab. 27 (3) 559-571.e5 [2018-03-06; online 2018-02-15]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Integrative Personal Omics Profiles during Periods of Weight Gain and Loss.
Piening BD, Zhou W, Contrepois K, ..., Weinstock GM, Snyder MP
Cell Systems 6 (2) 157-170.e8 [2018-02-28; online 2018-01-17]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Identification of Discriminating Metabolic Pathways and Metabolites in Human PBMCs Stimulated by Various Pathogenic Agents.
Zhang X, Mardinoglu A, Joosten LAB, ..., Netea MG, Groen AK
Front. Physiol. 9 (-) 139 [2018-02-27; online 2018-02-27]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
DOI Crossref
Associations of PD-1 and PD-L1 expression with mismatch repair status and prognosis in chemoradiotherapy-naïve esophageal and gastric adenocarcinoma.
Svensson M, Borg D, Zhang C, ..., Leandersson K, Jirstrom K
J Clin Oncol 36 (4_suppl) 9-9 [2018-02-01; online 2018-02-01]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Broad Views of Non-alcoholic Fatty Liver Disease.
Mardinoglu A, Uhlen M, Borén J
Cell Systems 6 (1) 7-9 [2018-01-24; online 2018-02-06]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Translational study reveals a two-faced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification.
Karnevi E, Dror LB, Mardinoglu A, ..., Uhlén M, Jirström K
Oncotarget 9 (5) 6188-6200 [2018-01-19; online 2017-12-15]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
TCSBN: a database of tissue and cancer specific biological networks.
Lee S, Zhang C, Arif M, ..., Uhlen M, Mardinoglu A
Nucleic Acids Res. 46 (D1) D595-D600 [2018-01-04; online 2017-10-27]
Adil Mardinoglu Affiliated researcher DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Letter: dose-response analysis revealed closer relationship between obesity and perioperative outcomes in patients after liver transplantation.
Liu Z, Mardinoglu A, Que S
Aliment. Pharmacol. Ther. 47 (2) 310-312 [2018-01-00; online 2017-12-22]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes.
Mardinoglu A, Gogg S, Lotta LA, ..., Laakso M, Smith U
EBioMedicine 27 (-) 151-155 [2018-01-00; online 2017-12-07]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
DOI Crossref
Network Analysis Reveals Heterogeneous Response of Redox Metabolism in Hepatocellular Carcinoma Patients
Benfeitas R, Bidkhori G, Mukhopadhyay B, ..., Kunos G, Mardinoglu A
SSRN Journal - (-) - [2018-00-00; online 2018-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow

Year 2017

PubMed DOI Crossref
Rediscussion on linearity between fibrosis stages and mortality risk in nonalcoholic fatty liver disease patients.
Liu Z, Que S, Mardinoglu A
Hepatology 66 (4) 1357-1358 [2017-10-00; online 2017-09-04]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Improving the economics of NASH/NAFLD treatment through the use of systems biology.
Bosley J, Boren C, Lee S, ..., Boren J, Mardinoglu A
Drug Discov. Today 22 (10) 1532-1538 [2017-10-00; online 2017-07-20]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
The effect of the TM6SF2 E167K variant on liver steatosis and fibrosis in patients with chronic hepatitis C: a meta-analysis.
Liu Z, Que S, Zhou L, ..., Mardinoglu A, Valenti L
Sci Rep 7 (1) 9273 [2017-08-24; online 2017-08-24]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Network analyses identify liver-specific targets for treating liver diseases.
Lee S, Zhang C, Liu Z, ..., Boren J, Mardinoglu A
Mol Syst Biol 13 (8) 938 [2017-08-21; online 2017-08-21]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
A pathology atlas of the human cancer transcriptome.
Uhlen M, Zhang C, Lee S, ..., Mardinoglu A, Ponten F
Science (New York, N.Y.) 357 (6352) eaan2507 [2017-08-18; online 2017-08-19]
Adil Mardinoglu Affiliated researcher DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease.
Mardinoglu A, Stančáková A, Lotta LA, ..., Langenberg C, Smith U
Cell Metab. 26 (2) 281-283 [2017-08-01; online 2017-08-03]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Vimentin deficiency in macrophages induces CD36-mediated inflammation
Håversen L, Ståhlman M, Mattson Hultén L, ..., Levin M, Borén J
Atherosclerosis 263 (-) e87-e88 [2017-08-00; online 2017-08-00]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
New Challenges to Study Heterogeneity in Cancer Redox Metabolism.
Benfeitas R, Uhlen M, Nielsen J, Mardinoglu A
Front Cell Dev Biol 5 (-) 65 [2017-07-11; online 2017-07-11]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
A subcellular map of the human proteome.
Thul PJ, Åkesson L, Wiking M, ..., Uhlén M, Lundberg E
Science (New York, N.Y.) 356 (6340) eaal3321 [2017-05-26; online 2017-05-11]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
AUP1 (Ancient Ubiquitous Protein 1): A Molecular Link Between Hepatic Lipid Mobilization and VLDL Secretion.
Mardinoglu A, Borén J
Arterioscler. Thromb. Vasc. Biol. 37 (4) 609-610 [2017-04-00; online 2017-03-24]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD.
Mardinoglu A, Bjornson E, Zhang C, ..., Taskinen MR, Boren J
Mol Syst Biol 13 (3) 916 [2017-03-02; online 2017-03-02]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Predicting growth of the healthy infant using a genome scale metabolic model.
Nilsson A, Mardinoglu A, Nielsen J
NPJ Syst Biol Appl 3 (1) 3 [2017-01-31; online 2017-01-31]
Adil Mardinoglu Avlant Nilsson SciLifeLab Fellow
PubMed DOI Crossref
Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity: a study of young healthy MZ twins.
Heinonen S, Muniandy M, Buzkova J, ..., Rissanen A, Pietiläinen KH
Diabetologia 60 (1) 169-181 [2017-01-00; online 2016-10-12]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

Year 2016

PubMed DOI Crossref
Editorial: The Impact of Systems Medicine on Human Health and Disease.
Mardinoglu A, Nielsen J
Front. Physiol. 7 (-) 552 [2016-11-24; online 2016-11-24]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Adaptive Evolution of Phosphorus Metabolism in Prochlorococcus.
Casey JR, Mardinoglu A, Nielsen J, Karl DM
mSystems 1 (6) - [2016-11-15; online 2016-11-15]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
ARAP2 promotes GLUT1-mediated basal glucose uptake through regulation of sphingolipid metabolism.
Chaudhari A, Håversen L, Mobini R, ..., Perkins R, Borén J
Biochim. Biophys. Acta 1861 (11) 1643-1651 [2016-11-00; online 2016-07-27]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Liver: Phenotypic and genetic variance: a systems approach to the liver.
Mardinoglu A, Uhlén M
Nat Rev Gastroenterol Hepatol 13 (8) 439-440 [2016-08-00; online 2016-06-22]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance.
Lee S, Zhang C, Kilicarslan M, ..., Boren J, Mardinoglu A
Cell Metab. 24 (1) 172-184 [2016-07-12; online 2016-06-23]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Dysregulated signaling hubs of liver lipid metabolism reveal hepatocellular carcinoma pathogenesis.
Lee S, Mardinoglu A, Zhang C, Lee D, Nielsen J
Nucleic Acids Res. 44 (12) 5529-5539 [2016-07-08; online 2016-05-23]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Investigating the Combinatory Effects of Biological Networks on Gene Co-expression.
Zhang C, Lee S, Mardinoglu A, Hua Q
Front. Physiol. 7 (-) 160 [2016-05-02; online 2016-05-02]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Systems biology analysis of hepatitis C virus infection reveals the role of copy number increases in regions of chromosome 1q in hepatocellular carcinoma metabolism.
Elsemman IE, Mardinoglu A, Shoaie S, Soliman TH, Nielsen J
Mol Biosyst 12 (5) 1496-1506 [2016-04-26; online 2016-04-05]
Adil Mardinoglu Affiliated researcher Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Transcriptomics resources of human tissues and organs.
Uhlén M, Hallström BM, Lindskog C, ..., Pontén F, Nielsen J
Mol Syst Biol 12 (4) 862 [2016-04-04; online 2016-04-04]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Personalized Cardiovascular Disease Prediction and Treatment-A Review of Existing Strategies and Novel Systems Medicine Tools.
Björnson E, Borén J, Mardinoglu A
Front. Physiol. 7 (-) 2 [2016-01-26; online 2016-01-26]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Confounding Effects of Metformin on the Human Gut Microbiome in Type 2 Diabetes.
Mardinoglu A, Boren J, Smith U
Cell Metab. 23 (1) 10-12 [2016-01-12; online 2016-01-16]
Adil Mardinoglu SciLifeLab Fellow

Year 2015

PubMed DOI Crossref
The gut microbiota modulates host amino acid and glutathione metabolism in mice
Mardinoglu A, Shoaie S, Bergentall M, ..., Bäckhed F, Nielsen J
Mol Syst Biol 11 (10) 834 [2015-10-00; online 2015-10-16]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome.
Shoaie S, Ghaffari P, Kovatcheva-Datchary P, ..., Bäckhed F, Nielsen J
Cell Metab. 22 (2) 320-331 [2015-08-04; online 2015-08-06]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Logical transformation of genome-scale metabolic models for gene level applications and analysis.
Zhang C, Ji B, Mardinoglu A, Nielsen J, Hua Q
Bioinformatics 31 (14) 2324-2331 [2015-07-15; online 2015-03-02]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Proteome- and transcriptome-driven reconstruction of the human myocyte metabolic network and its use for identification of markers for diabetes.
Väremo L, Scheele C, Broholm C, ..., Pedersen BK, Nielsen J
Cell Reports 11 (6) 921-933 [2015-05-12; online 2015-04-30]
Adil Mardinoglu SciLifeLab Fellow

Year 2014

PubMed DOI Crossref
Toxicogenomics directory of chemically exposed human hepatocytes
Grinberg M, Stöber RM, Edlund K, ..., Rahnenführer J, Hengstler JG
Arch Toxicol 88 (12) 2261-2287 [2014-12-00; online 2014-11-16]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
DOI Crossref
The use of Genome-scale metabolic models for drug target and biomarker identification
Mardinoglu A, Uhlen M, Nielsen J
New Biotechnology 31 (-) S49 [2014-07-00; online 2014-07-00]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

Year 2013

PubMed DOI Crossref
Understanding the interactions between bacteria in the human gut through metabolic modeling
Shoaie S, Karlsson F, Mardinoglu A, ..., Bordel S, Nielsen J
Sci Rep 3 (1) - [2013-12-00; online 2013-08-28]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Genome-scale modeling of human metabolism - a systems biology approach
Mardinoglu A, Gatto F, Nielsen J
Biotechnology Journal 8 (9) 985-996 [2013-09-00; online 2013-04-24]
Adil Mardinoglu SciLifeLab Fellow

Year 2012

PubMed DOI Crossref
Reconstruction of Genome-Scale Active Metabolic Networks for 69 Human Cell Types and 16 Cancer Types Using INIT
Agren R, Bordel S, Mardinoglu A, ..., Nookaew I, Nielsen J
PLoS Comput Biol 8 (5) e1002518 [2012-05-17; online 2012-05-17]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Systems medicine and metabolic modelling.
Mardinoglu A, Nielsen J
J. Intern. Med. 271 (2) 142-154 [2012-02-00; online 2011-12-07]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Inclusion of interactions in mathematical modelling of implant assisted magnetic drug targeting
Cregg PJ, Murphy K, Mardinoglu A
Applied Mathematical Modelling 36 (1) 1-34 [2012-01-00; online 2012-01-00]
Adil Mardinoglu SciLifeLab Fellow

Year 2011

DOI Crossref
Theoretical modelling of physiologically stretched vessel in magnetisable stent assisted magnetic drug targeting application
Mardinoglu A, Cregg PJ, Murphy K, Curtin M, Prina-Mello A
Journal of Magnetism and Magnetic Materials 323 (3-4) 324-329 [2011-02-00; online 2011-02-00]
Adil Mardinoglu SciLifeLab Fellow

Year 2010

DOI Crossref
Many particle magnetic dipole–dipole and hydrodynamic interactions in magnetizable stent assisted magnetic drug targeting
Cregg PJ, Murphy K, Mardinoglu A, Prina-Mello A
Journal of Magnetism and Magnetic Materials 322 (15) 2087-2094 [2010-08-00; online 2010-08-00]
Adil Mardinoglu SciLifeLab Fellow

Year 2008

DOI Crossref
Calculation of nanoparticle capture efficiency in magnetic drug targeting
Cregg PJ, Murphy K, Mardinoglu A
Journal of Magnetism and Magnetic Materials 320 (23) 3272-3275 [2008-12-00; online 2008-12-00]
Adil Mardinoglu SciLifeLab Fellow
SciLifeLab Data Centre
Publications 9.5.1