JCI Insight

Loss of genome maintenance is linked to mTOR complex 1 signaling and accelerates podocyte damage.

Braun F, Mandel AM, Blomberg L, ..., Schumacher B, Kurschat CE

JCI Insight 10 (12) - [2025-06-23; online 2025-05-20]

Combination treatment with anti-RANKL and antibiotics for preventing joint destruction in septic arthritis.

Hu Z, Deshmukh M, Jarneborn A, ..., Mohammad M, Jin T

JCI Insight 10 (6) - [2025-03-24; online 2025-03-24]

CD93 maintains endothelial barrier function and limits metastatic dissemination.

Vemuri K, de Alves Pereira B, Fuenzalida P, ..., Lugano R, Dimberg A

JCI Insight 9 (7) - [2024-03-05; online 2024-03-05]

NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE.

Georgakis S, Gkirtzimanaki K, Papadaki G, ..., Verginis P, Bertsias G

JCI Insight 6 (21) - [2021-11-08; online 2021-11-08]

Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing.

Xie Y, He L, Lugano R, ..., Dimberg A, Zhang L

JCI Insight 6 (15) - [2021-08-09; online 2021-08-09]

eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancer.

Müller D, Shin S, Goullet de Rugy T, ..., Pyronnet S, Martineau Y

JCI Insight 4 (21) - [2019-11-01; online 2019-11-01]

Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection.

Zychlinsky Scharff A, Rousseau M, Lacerda Mariano L, ..., Duffy D, Ingersoll MA

JCI Insight 5 (13) - [2019-05-30; online 2019-05-30]

Camila Consiglio DDLS Fellow