Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.

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Deville C, Carroni M, Franke KB, Topf M, Bukau B, Mogk A, Saibil HR

Sci Adv 3 (8) e1701726 [2017-08-00; online 2017-08-04]

Refolding aggregated proteins is essential in combating cellular proteotoxic stress. Together with Hsp70, Hsp100 chaperones, including

Affiliated researcher

PubMed 28798962

DOI 10.1126/sciadv.1701726

Crossref 10.1126/sciadv.1701726

pii: 1701726
pmc: PMC5544394