Cytotoxic T cells in chronic idiopathic neutropenia express restricted antigen receptors.

Mastrodemou S, Stalika E, Vardi A, Gemenetzi K, Spanoudakis M, Karypidou M, Mavroudi I, Hadzidimitriou A, Stavropoulos-Giokas C, Papadaki HA, Stamatopoulos K

Leuk. Lymphoma 58 (12) 2926-2933 [2017-12-00; online 2017-05-23]

Chronic idiopathic neutropenia (CIN) is an acquired disorder of granulopoiesis characterized by female predominance and mostly uncomplicated course. Crucial to CIN pathophysiology is the presence of activated T lymphocytes with myelosuppressive properties in both peripheral blood (PB) and bone marrow (BM). We systematically profiled the T cell receptor beta chain (TRB) gene repertoire in CD8

Affiliated researcher

PubMed 28535087

DOI 10.1080/10428194.2017.1324154

Crossref 10.1080/10428194.2017.1324154

Publications 9.5.0