Bioorg. Med. Chem. Lett.

Synthesis and kinetic evaluation of phosphomimetic inhibitors targeting type B ribose-5-phosphate isomerase from Mycobacterium tuberculosis.

Courtiol-Legourd S, Mariano S, Foret J, ..., Mowbray SL, Salmon L

Bioorg. Med. Chem. Lett. 102 (-) 129666 [2024-04-01; online 2024-02-19]

Discovery and characterisation of quinazolines and 8-Azaquinazolines as NLRP3 agonists with oral bioavailability in mice.

O' Donovan DH, Baker D, Ciotta G, ..., Tang H, Valge-Archer V

Bioorg. Med. Chem. Lett. 96 (-) 129518 [2023-10-12; online 2023-10-12]

SciLifeLab Fellow Yumeng Mao

An imidazole based H-Phe-Phe-NH2 peptidomimetic with anti-allodynic effect in spared nerve injury mice.

Skogh A, Lesniak A, Sköld C, ..., Hallberg M, Sandström A

Bioorg. Med. Chem. Lett. 28 (14) 2446-2450 [2018-08-01; online 2018-06-15]

A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes.

Wannberg J, Isaksson R, Bremberg U, ..., Hallberg M, Larhed M

Bioorg. Med. Chem. Lett. 28 (3) 519-522 [2018-02-01; online 2017-11-24]

Tetrahydrobenzothiophene carboxamides: Beyond the kinase domain and into the fatty acid realm.

Llona-Minguez S, Fayezi S, Alihemmati A, ..., Piedrafita FJ, Helleday T

Bioorg. Med. Chem. Lett. 27 (18) 4462-4466 [2017-09-15; online 2017-08-05]

Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 1: Triazoles, triazolopyrimidines, triazinoindoles, quinoline hydrazones and arylpiperazines.

Llona-Minguez S, Häggblad M, Martens U, ..., Scobie M, Helleday T

Bioorg. Med. Chem. Lett. 27 (16) 3897-3904 [2017-08-15; online 2017-06-16]

Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG).

Globisch D, Eubanks LM, Shirey RJ, ..., Hoerauf A, Janda KD

Bioorg. Med. Chem. Lett. 27 (15) 3436-3440 [2017-08-01; online 2017-05-29]

Affiliated researcher Daniel Globisch SciLifeLab Fellow

Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 2: Pyridone- and pyrimidinone-derived systems.

Llona-Minguez S, Häggblad M, Martens U, ..., Scobie M, Helleday T

Bioorg. Med. Chem. Lett. 27 (15) 3219-3225 [2017-08-01; online 2017-06-15]

Litomosoides sigmodontis: a jird urine metabolome study.

Globisch D, Specht S, Pfarr KM, ..., Hoerauf A, Janda KD

Bioorg. Med. Chem. Lett. 25 (24) 5804-5807 [2015-12-15; online 2015-10-23]

Daniel Globisch SciLifeLab Fellow