Nat. Biotechnol.

ISSN	1546-1696
ISSN-L	1087-0156
IUID	9da9ecd066214f30907485725a9cbdc5
Modified	2020-11-27T13:12:55.423Z
Created	2018-12-05T08:18:14.584Z

Year 2026

PubMed DOI Crossref

Tissue and cellular spatiotemporal dynamics in colon aging.

Daly AC, Cambuli F, Äijö T, ..., Regev A, Vickovic S

Nat. Biotechnol. 44 (8) 1340-1352 [2026-08-00; online 2025-10-22]

Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

A tissue-specific atlas of protein-protein associations enables prioritization of candidate disease genes.

Laman Trip DS, van Oostrum M, Memon D, ..., Wollscheid B, Beltrao P

Nat. Biotechnol. 44 (4) 654-667 [2026-04-00; online 2025-05-02]

Andrea Fossati DDLS Fellow

Year 2025

PubMed DOI Crossref

Defining and benchmarking open problems in single-cell analysis.

Luecken MD, Gigante S, Burkhardt DB, ..., Theis FJ, Krishnaswamy S

Nat. Biotechnol. 43 (7) 1035-1040 [2025-07-00; online 2025-07-02]

PubMed DOI Crossref

Putting cancer immunotherapy into spatial context in the clinic.

Engblom C, Lundeberg J

Nat. Biotechnol. 43 (4) 471-476 [2025-04-00; online 2025-04-15]

Camilla Engblom SciLifeLab Fellow

Year 2024

PubMed DOI Crossref

Spatial host-microbiome sequencing reveals niches in the mouse gut.

Lötstedt B, Stražar M, Xavier R, Regev A, Vickovic S

Nat. Biotechnol. 42 (9) 1394-1403 [2024-09-00; online 2023-11-20]

Sanja Vickovic SciLifeLab Fellow

PubMed DOI Crossref

Spatial metatranscriptomics resolves host-bacteria-fungi interactomes.

Saarenpää S, Shalev O, Ashkenazy H, ..., Weigel D, Giacomello S

Nat. Biotechnol. 42 (9) 1384-1393 [2024-09-00; online 2023-11-20]

PubMed DOI Crossref

Detection of transcriptome-wide microRNA-target interactions in single cells with agoTRIBE.

Sekar V, Mármol-Sánchez E, Kalogeropoulos P, ..., Biryukova I, Friedländer MR

Nat. Biotechnol. 42 (8) 1296-1302 [2024-08-00; online 2023-09-21]

Marc Friedländer SciLifeLab Fellow

PubMed DOI Crossref

A community effort to track commercial single-cell and spatial 'omic technologies and business trends.

De Jonghe J, Opzoomer JW, Vilas-Zornoza A, ..., Cribbs AP, Taylor-King JP

Nat. Biotechnol. 42 (7) 1017-1023 [2024-07-00; online 2024-07-18]

PubMed DOI Crossref

Spatial multimodal analysis of transcriptomes and metabolomes in tissues.

Vicari M, Mirzazadeh R, Nilsson A, ..., Andrén PE, Lundeberg J

Nat. Biotechnol. 42 (7) 1046-1050 [2024-07-00; online 2023-09-04]

PubMed DOI Crossref

High-throughput measurement of the content and properties of nano-sized bioparticles with single-particle profiler.

Sych T, Schlegel J, Barriga HMG, ..., Stevens MM, Sezgin E

Nat. Biotechnol. 42 (4) 587-590 [2024-04-00; online 2023-06-12]

Daniel Fürth Erdinc Sezgin SciLifeLab Fellow

Year 2023

PubMed DOI Crossref

Solid-phase capture and profiling of open chromatin by spatial ATAC.

Llorens-Bobadilla E, Zamboni M, Marklund M, ..., Frisén J, Ståhl PL

Nat. Biotechnol. 41 (8) 1085-1088 [2023-08-00; online 2023-01-05]

PubMed DOI Crossref

Author Correction: Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.

Allesøe RL, Lundgaard AT, Hernández Medina R, ..., Brunak S, IMI DIRECT Consortium

Nat. Biotechnol. 41 (7) 1026 [2023-07-00; online 2023-05-03]

PubMed DOI Crossref

Author Correction: Butler enables rapid cloud-based analysis of thousands of human genomes.

Yakneen S, Waszak SM, PCAWG Technical Working Group , ..., Korbel JO, PCAWG Consortium

Nat. Biotechnol. 41 (4) 577 [2023-04-00; online 2023-03-23]

PubMed DOI Crossref

Extending fluorescence anisotropy to large complexes using reversibly switchable proteins.

Volpato A, Ollech D, Alvelid J, ..., Ingaramo M, Testa I

Nat. Biotechnol. 41 (4) 552-559 [2023-04-00; online 2022-10-10]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.

Allesøe RL, Lundgaard AT, Hernández Medina R, ..., Brunak S, IMI DIRECT Consortium

Nat. Biotechnol. 41 (3) 399-408 [2023-03-00; online 2023-01-02]

Year 2022

PubMed DOI Crossref

Deep Visual Proteomics defines single-cell identity and heterogeneity.

Mund A, Coscia F, Kriston A, ..., Horvath P, Mann M

Nat. Biotechnol. 40 (8) 1231-1240 [2022-08-00; online 2022-05-19]

PubMed DOI Crossref

SignalP 6.0 predicts all five types of signal peptides using protein language models.

Teufel F, Almagro Armenteros JJ, Johansen AR, ..., von Heijne G, Nielsen H

Nat. Biotechnol. 40 (7) 1023-1025 [2022-07-00; online 2022-01-03]

PubMed DOI Crossref

An open invitation to the Understudied Proteins Initiative.

Kustatscher G, Collins T, Gingras AC, ..., Ralser M, Rappsilber J

Nat. Biotechnol. 40 (6) 815-817 [2022-06-00; online 2022-05-10]

PubMed DOI Crossref

Super-resolved spatial transcriptomics by deep data fusion.

Bergenstråhle L, He B, Bergenstråhle J, ..., Lundeberg J, Maaskola J

Nat. Biotechnol. 40 (4) 476-479 [2022-04-00; online 2021-11-29]

PubMed DOI Crossref

Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging.

Mishra K, Fuenzalida-Werner JP, Pennacchietti F, ..., Ntziachristos V, Stiel AC

Nat. Biotechnol. 40 (4) 598-605 [2022-04-00; online 2021-11-29]

Ilaria Testa SciLifeLab Fellow

Year 2021

PubMed DOI Crossref

Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing.

Xiao W, Ren L, Chen Z, ..., Wang C, Shi L

Nat. Biotechnol. 39 (9) 1141-1150 [2021-09-00; online 2021-09-09]

PubMed DOI Crossref

Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing.

Fang LT, Zhu B, Zhao Y, ..., Xiao W, Somatic Mutation Working Group of Sequencing Quality Control Phase II Consortium

Nat. Biotechnol. 39 (9) 1151-1160 [2021-09-00; online 2021-09-09]

PubMed DOI Crossref

Volumetric live cell imaging with three-dimensional parallelized RESOLFT microscopy.

Bodén A, Pennacchietti F, Coceano G, ..., Ratz M, Testa I

Nat. Biotechnol. 39 (5) 609-618 [2021-05-00; online 2021-01-11]

Ilaria Testa SciLifeLab Fellow

PubMed DOI Crossref

Author Correction: A genomic catalog of Earth's microbiomes.

Nayfach S, Roux S, Seshadri R, ..., Kyrpides NC, Eloe-Fadrosh EA

Nat. Biotechnol. 39 (4) 521 [2021-04-00; online 2021-04-03]

PubMed DOI Crossref

Publisher Correction: A genomic catalog of Earth's microbiomes.

Nayfach S, Roux S, Seshadri R, ..., Kyrpides NC, Eloe-Fadrosh EA

Nat. Biotechnol. 39 (4) 520 [2021-04-00; online 2020-11-20]

Year 2020

PubMed DOI Crossref

GPSeq reveals the radial organization of chromatin in the cell nucleus.

Girelli G, Custodio J, Kallas T, ..., Crosetto N, Bienko M

Nat. Biotechnol. 38 (10) 1184-1193 [2020-10-00; online 2020-05-25]

Magda Bienko SciLifeLab Fellow

PubMed DOI Crossref

Publisher Correction: MEMOTE for standardized genome-scale metabolic model testing.

Lieven C, Beber ME, Olivier BG, ..., Zakhartsev M, Zhang C

Nat. Biotechnol. 38 (4) 504 [2020-04-00; online 2020-04-09]

Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

Butler enables rapid cloud-based analysis of thousands of human genomes.

Yakneen S, Waszak SM, PCAWG Technical Working Group , ..., Korbel JO, PCAWG Consortium

Nat. Biotechnol. 38 (3) 288-292 [2020-03-00; online 2020-02-05]

PubMed DOI Crossref

MEMOTE for standardized genome-scale metabolic model testing.

Lieven C, Beber ME, Olivier BG, ..., Zakhartsev M, Zhang C

Nat. Biotechnol. 38 (3) 272-276 [2020-03-00; online 2020-03-04]

Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

The nf-core framework for community-curated bioinformatics pipelines.

Ewels PA, Peltzer A, Fillinger S, ..., Di Tommaso P, Nahnsen S

Nat. Biotechnol. 38 (3) 276-278 [2020-03-00; online 2020-02-15]

Year 2019

PubMed DOI Crossref

Goodbye reference, hello genome graphs.

Ameur A

Nat. Biotechnol. 37 (8) 866-868 [2019-08-00; online 2019-08-04]

PubMed DOI Crossref

SignalP 5.0 improves signal peptide predictions using deep neural networks.

Almagro Armenteros JJ, Tsirigos KD, Sønderby CK, ..., von Heijne G, Nielsen H

Nat. Biotechnol. 37 (4) 420-423 [2019-04-00; online 2019-02-18]

Year 2018

PubMed DOI Crossref

Deep learning is combined with massive-scale citizen science to improve large-scale image classification.

Sullivan DP, Winsnes CF, Åkesson L, ..., Szantner A, Lundberg E

Nat. Biotechnol. 36 (9) 820-828 [2018-10-00; online 2018-08-20]

PubMed DOI Crossref

A protein activity assay to measure global transcription factor activity reveals determinants of chromatin accessibility.

Wei B, Jolma A, Sahu B, ..., Taipale M, Taipale J

Nat. Biotechnol. 36 (6) 521-529 [2018-07-00; online 2018-05-21]

PubMed DOI Crossref

Recon3D enables a three-dimensional view of gene variation in human metabolism.

Brunk E, Sahoo S, Zielinski DC, ..., Thiele I, Palsson BO

Nat. Biotechnol. 36 (3) 272-281 [2018-03-00; online 2018-02-19]

Avlant Nilsson DDLS Fellow

Year 2017

PubMed DOI Crossref

Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea.

Bowers RM, Kyrpides NC, Stepanauskas R, ..., Hugenholtz P, Woyke T

Nat. Biotechnol. 35 (8) 725-731 [2017-08-08; online 2017-08-09]

PubMed DOI Crossref

Engineered Cpf1 variants with altered PAM specificities.

Gao L, Cox DBT, Yan WX, ..., Crosetto N, Zhang F

Nat. Biotechnol. 35 (8) 789-792 [2017-08-00; online 2017-06-05]

Year 2016

PubMed DOI Crossref

Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction.

Mooijman D, Dey SS, Boisset JC, Crosetto N, van Oudenaarden A

Nat. Biotechnol. 34 (8) 852-856 [2016-08-00; online 2016-06-27]

Year 2015

PubMed DOI Crossref

Integrated genome and transcriptome sequencing of the same cell.

Dey SS, Kester L, Spanjaard B, Bienko M, van Oudenaarden A

Nat. Biotechnol. 33 (3) 285-289 [2015-03-00; online 2015-01-19]

Magda Bienko SciLifeLab Fellow

Year 2013

PubMed DOI Crossref

Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories.

't Hoen PA, Friedländer MR, Almlöf J, ..., Dermitzakis ET, Lappalainen T

Nat. Biotechnol. 31 (11) 1015-1022 [2013-11-00; online 2013-09-15]

Year 2011

PubMed DOI Crossref

Full-length transcriptome assembly from RNA-Seq data without a reference genome.

Grabherr MG, Haas BJ, Yassour M, ..., Friedman N, Regev A

Nat. Biotechnol. 29 (7) 644-652 [2011-05-15; online 2011-05-15]

PubMed DOI Crossref

Comprehensive assessment of array-based platforms and calling algorithms for detection of copy number variants.

Pinto D, Darvishi K, Shi X, ..., Scherer SW, Feuk L

Nat. Biotechnol. 29 (6) 512-520 [2011-05-08; online 2011-05-08]

Year 2010

PubMed DOI Crossref

Towards a knowledge-based Human Protein Atlas.

Uhlen M, Oksvold P, Fagerberg L, ..., Björling L, Ponten F

Nat. Biotechnol. 28 (12) 1248-1250 [2010-12-00; online 2010-12-09]

Year 2008

PubMed DOI Crossref

Discovering microRNAs from deep sequencing data using miRDeep.

Friedländer MR, Chen W, Adamidi C, ..., Knespel S, Rajewsky N

Nat. Biotechnol. 26 (4) 407-415 [2008-04-00; online 2008-04-09]

Marc Friedländer SciLifeLab Fellow