Amunts A

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Family name Amunts
Given name Alexey
Initials A
ORCID

ORCID 0000-0002-5302-1740
Affiliations

79 publications

PubMed DOI Crossref
The mitochondrial methylation potential gates mitoribosome assembly.
Glasgow RIC, Singh V, Peña-Pérez L, ..., Amunts A, Wredenberg A
Nat Commun 16 (1) 5388 [2025-06-25; online 2025-06-25]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Mettl15-Mettl17 modulates the transition from early to late pre-mitoribosome.
Zgadzay Y, Mirabello C, Wanes G, ..., Gahura O, Amunts A
bioRxiv - (-) - [2025-01-24; online 2025-01-24]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome.
Singh V, Moran JC, Itoh Y, ..., Barrientos A, Amunts A
Nat. Struct. Mol. Biol. 31 (12) 1838-1847 [2024-12-00; online 2024-08-12]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Publisher Correction: Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome.
Singh V, Moran JC, Itoh Y, ..., Barrientos A, Amunts A
Nat. Struct. Mol. Biol. 31 (11) 1809 [2024-11-00; online 2024-09-20]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Structure of plant photosystem I in a native assembly state defines PsaF as a regulatory checkpoint.
Naschberger A, Fadeeva M, Klaiman D, ..., Nelson N, Amunts A
Nat Plants 10 (6) 874-879 [2024-06-00; online 2024-05-30]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Author Correction: Structure of plant photosystem I in a native assembly state defines PsaF as a regulatory checkpoint.
Naschberger A, Fadeeva M, Klaiman D, ..., Nelson N, Amunts A
Nat Plants 10 (6) 1054 [2024-06-00; online 2024-06-11]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Structure of the II2-III2-IV2 mitochondrial supercomplex from the parasite Perkinsus marinus
Wú F, Mühleip A, Gruhl T, ..., Maréchal A, Amunts A
- - (-) - [2024-05-25; online 2024-05-25]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk.
Singh V, Itoh Y, Del'Olio S, ..., Taoka M, Amunts A
Nat Commun 15 (1) 4272 [2024-05-20; online 2024-05-20]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Structural basis of mitochondrial membrane bending by the I-II-III2-IV2 supercomplex.
Mühleip A, Flygaard RK, Baradaran R, ..., Sharma V, Amunts A
Nature 615 (7954) 934-938 [2023-03-00; online 2023-03-22]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Structure of plant Photosystem I in a native assembly state
Naschberger A, Fadeeva M, Klaiman D, ..., Nelson N, Amunts A
- - (-) - [2022-12-28; online 2022-12-28]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Structure of the mitoribosomal small subunit with streptomycin reveals Fe-S clusters and physiological molecules.
Itoh Y, Singh V, Khawaja A, ..., Rorbach J, Amunts A
Elife 11 (-) - [2022-12-08; online 2022-12-08]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
METTL17 is an Fe-S cluster checkpoint for mitochondrial translation
Ast T, Itoh Y, Sadre S, ..., Amunts A, Mootha VK
bioRxiv - (-) - [2022-11-24; online 2022-11-24]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Structure of a mitochondrial ribosome with fragmented rRNA in complex with membrane-targeting elements.
Tobiasson V, Berzina I, Amunts A
Nat Commun 13 (1) 6132 [2022-10-17; online 2022-10-17]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Gahura O, Mühleip A, Hierro-Yap C, ..., Zíková A, Amunts A
Nat Commun 13 (1) 5989 [2022-10-11; online 2022-10-11]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Algal photosystem I dimer and high-resolution model of PSI-plastocyanin complex.
Naschberger A, Mosebach L, Tobiasson V, ..., Hippler M, Amunts A
Nat Plants 8 (10) 1191-1201 [2022-10-00; online 2022-10-13]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Author response: Structure of the mitoribosomal small subunit with streptomycin reveals Fe-S clusters and physiological molecules
Itoh Y, Singh V, Khawaja A, ..., Rorbach J, Amunts A
- - (-) - [2022-09-09; online 2022-09-09]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Structural basis of mitochondrial membrane bending by I-II-III2-IV2 supercomplex
Mühleip A, Flygaard RK, Haapanen O, ..., Sharma V, Amunts A
- - (-) - [2022-06-26; online 2022-06-26]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome
Singh V, Conor Moran J, Itoh Y, ..., Barrientos A, Amunts A
- - (-) - [2022-06-20; online 2022-06-20]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Itoh Y, Khawaja A, Laptev I, ..., Rorbach J, Amunts A
Nature 606 (7914) 603-608 [2022-06-00; online 2022-06-08]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Structural basis of streptomycin off-target binding to human mitoribosome
Itoh Y, Khawaja A, Singh V, ..., Rorbach J, Amunts A
- - (-) - [2022-02-02; online 2022-02-02]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
The revolution evolution.
Amunts A
Nat Plants 8 (1) 14-17 [2022-01-00; online 2021-12-18]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases
Amunts A, Gahura O, Muhleip A, ..., Slapničková M, Zikova A
- - (-) - [2021-12-30; online 2021-12-30]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases
Gahura O, Mühleip A, Hierro-Yap C, ..., Zíková A, Amunts A
bioRxiv - (-) - [2021-10-10; online 2021-10-10]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Algal photosystem I dimer and high resolution model of PSI:plastocyanin complex
Naschberger A, Mosebach L, Tobiasson V, ..., Hippler M, Amunts A
- - (-) - [2021-08-31; online 2021-08-31]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structural basis of LhcbM5-mediated state transitions in green algae.
Amunts A
- - (-) - [2021-08-27; online 2021-08-24]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Repurposing tRNAs for nonsense suppression.
Amunts A
- - (-) - [2021-08-27; online 2021-08-24]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
Tobiasson V, Gahura O, Aibara S, ..., Zíková A, Amunts A
EMBO J. 40 (6) e106292 [2021-03-15; online 2021-02-12]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Mechanism of membrane-tethered mitochondrial protein synthesis.
Itoh Y, Andréll J, Choi A, ..., Battersby BJ, Amunts A
Science (New York, N.Y.) 371 (6531) 846-849 [2021-02-19; online 2021-02-20]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria.
Mühleip A, Kock Flygaard R, Ovciarikova J, ..., Sheiner L, Amunts A
Nat Commun 12 (1) 120 [2021-01-05; online 2021-01-05]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization.
Flygaard RK, Mühleip A, Tobiasson V, Amunts A
Nat Commun 11 (1) 5342 [2020-10-22; online 2020-10-22]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi.
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM, Amunts A
Nat Commun 11 (1) 5187 [2020-10-14; online 2020-10-14]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Structural basis of mitochondrial translation.
Aibara S, Singh V, Modelska A, Amunts A
Elife 9 (-) - [2020-08-19; online 2020-08-19]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Author response: Structural basis of mitochondrial translation
Aibara S, Singh V, Modelska A, Amunts A
- - (-) - [2020-07-24; online 2020-07-24]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit
Tobiasson V, Gahura O, Aibara S, ..., Zíková A, Amunts A
bioRxiv - (-) - [2020-06-29; online 2020-06-29]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation.
Tobiasson V, Amunts A
Elife 9 (-) e59264 [2020-06-18; online 2020-06-18]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Distinct pre-initiation steps in human mitochondrial translation.
Khawaja A, Itoh Y, Remes C, ..., Amunts A, Rorbach J
Nat Commun 11 (1) 2932 [2020-06-10; online 2020-06-10]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Author response: Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation
Tobiasson V, Amunts A
- - (-) - [2020-06-08; online 2020-06-08]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Structure of a minimal photosystem I from the green alga Dunaliella salina.
Perez-Boerema A, Klaiman D, Caspy I, ..., Amunts A, Nelson N
Nat Plants 6 (3) 321-327 [2020-03-00; online 2020-03-02]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Distinct structural modulation of photosystem I and lipid environment stabilizes its tetrameric assembly.
Chen M, Perez-Boerema A, Zhang L, ..., Li S, Amunts A
Nat Plants 6 (3) 314-320 [2020-03-00; online 2020-03-09]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM, Amunts A
bioRxiv - (-) - [2020-02-02; online 2020-02-02]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structure and activation mechanism of the BBSome membrane protein trafficking complex.
Amunts A
- - (-) - [2020-01-21; online 2020-01-18]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of A mitochondrial megachannel resides in monomeric F1FO ATP synthase.
Amunts A
- - (-) - [2020-01-02; online 2019-12-26]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent.
Amunts A
- - (-) - [2020-01-02; online 2019-12-26]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system.
Amunts A
- - (-) - [2020-01-02; online 2019-12-22]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B.
Amunts A
- - (-) - [2020-01-02; online 2019-12-25]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of In Situ Structure of an Intact Lipopolysaccharide-Bound Bacterial Surface Layer.
Amunts A
- - (-) - [2020-01-02; online 2019-12-27]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Analysis of the Human Protein Atlas Image Classification competition.
Amunts A
- - (-) - [2020-01-02; online 2019-12-25]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Structure of a mitochondrial ATP synthase with bound native cardiolipin.
Mühleip A, McComas SE, Amunts A
Elife 8 (-) - [2019-11-18; online 2019-11-18]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Author response: Structure of a mitochondrial ATP synthase with bound native cardiolipin
Mühleip A, McComas SE, Amunts A
- - (-) - [2019-11-12; online 2019-11-12]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome.
Amunts A
- - (-) - [2019-08-06; online 2019-08-04]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of A cryo-FIB lift-out technique enables molecular-resolution cryo-ET within native Caenorhabditis elegans tissue.
Amunts A
- - (-) - [2019-08-06; online 2019-08-05]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nirwan N, Itoh Y, Singh P, ..., Amunts A, Saikrishnan K
Nat Commun 10 (1) 3058 [2019-07-11; online 2019-07-11]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain.
Bigalke JM, Aibara S, Roth R, ..., Amunts A, Sandmark J
Sci Adv 5 (7) eaau4202 [2019-07-00; online 2019-07-31]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Zinc depletion does not necessarily induce ribosome hibernation in mycobacteria.
Tobiasson V, Dow A, Prisic S, Amunts A
Proc. Natl. Acad. Sci. U.S.A. 116 (7) 2395-2397 [2019-02-12; online 2019-01-25]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Rapid Isolation of the Mitoribosome from HEK Cells.
Aibara S, Andréll J, Singh V, Amunts A
J Vis Exp - (140) - [2018-10-04; online 2018-10-04]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Publisher Correction: Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor.
Perez Boerema A, Aibara S, Paul B, ..., Lindahl E, Amunts A
Nat Plants 4 (8) 615 [2018-08-00; online 2018-07-25]
Alexey Amunts Björn Forsberg DDLS Fellow SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Mitochondrial translation efficiency controls cytoplasmic protein homeostasis.
Amunts A
- - (-) - [2018-05-14; online 2018-05-12]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.
Amunts A
- - (-) - [2018-04-13; online 2018-04-13]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor.
Perez Boerema A, Aibara S, Paul B, ..., Lindahl E, Amunts A
Nat Plants 4 (4) 212-217 [2018-04-00; online 2018-04-02]
Affiliated researcher Alexey Amunts Björn Forsberg DDLS Fellow SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structure of a prehandover mammalian ribosomal SRP·SRP receptor targeting complex.
Amunts A
- - (-) - [2018-03-27; online 2018-03-24]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of The 3.5-Å CryoEM Structure of Nanodisc-Reconstituted Yeast Vacuolar ATPase Vo Proton Channel.
Amunts A
- - (-) - [2018-03-27; online 2018-03-25]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Farming the mitochondrial ancestor as a model of endosymbiotic establishment by natural selection.
Amunts A
- - (-) - [2018-03-27; online 2018-03-26]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of A transfer-RNA-derived small RNA regulates ribosome biogenesis.
Amunts A
- - (-) - [2018-03-19; online 2018-03-11]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.
Amunts A
- - (-) - [2018-03-19; online 2018-03-11]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Kinetics and mechanism of mammalian mitochondrial ribosome assembly.
Amunts A
- - (-) - [2018-03-16; online 2018-03-10]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Non-canonical Binding Site for Bacterial Initiation Factor 3 on the Large Ribosomal Subunit.
Amunts A
- - (-) - [2018-03-16; online 2018-03-10]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Maturation of selected human mitochondrial tRNAs requires deadenylation.
Amunts A
- - (-) - [2018-03-16; online 2018-03-10]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structure and conformational dynamics of the human spliceosomal bact complex.
Amunts A
- - (-) - [2018-02-19; online 2018-02-18]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of 3D visualization of mitochondrial solid-phase calcium stores in whole cells.
Amunts A
- - (-) - [2018-01-11; online 2018-01-04]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Pausing of chloroplast ribosomes is induced by multiple features and is linked to the assembly of photosynthetic complexes.
Amunts A
- - (-) - [2018-01-11; online 2018-01-08]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of AMD1 mRNA employs ribosome stalling as a mechanism for molecular memory formation.
Amunts A
- - (-) - [2018-01-11; online 2018-01-08]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Identification of oxa1 homologs operating in the eukaryotic endoplasmic reticulum.
Amunts A
- - (-) - [2018-01-11; online 2018-01-07]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of The complete structure of the small-subunit processome.
Amunts A
- - (-) - [2017-12-21; online 2017-12-17]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of The ER membrane protein complex is a transmembrane domain insertase.
Amunts A
- - (-) - [2017-12-21; online 2017-12-17]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Structural basis of proton translocation and force generation in mitochondrial ATP synthase.
Amunts A
- - (-) - [2017-12-20; online 2017-12-17]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Ribosome origami.
Rorbach J, Aibara S, Amunts A
Nat. Struct. Mol. Biol. 24 (11) 879-881 [2017-11-07; online 2017-11-08]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Cryo-EM reconstruction of the chlororibosome to 3.2 Å resolution within 24 h.
Forsberg BO, Aibara S, Kimanius D, ..., Lindahl E, Amunts A
IUCrJ 4 (Pt 6) 723-727 [2017-11-01; online 2017-09-22]
Alexey Amunts Björn Forsberg DDLS Fellow SciLifeLab Fellow
PubMed DOI Crossref
Structures of the human mitochondrial ribosome in native states of assembly.
Brown A, Rathore S, Kimanius D, ..., Amunts A, Ramakrishnan V
Nat. Struct. Mol. Biol. 24 (10) 866-869 [2017-10-00; online 2017-09-11]
Affiliated researcher Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus.
Matzov D, Aibara S, Basu A, ..., Amunts A, Yonath AE
Nat Commun 8 (1) 723 [2017-09-28; online 2017-09-28]
Affiliated researcher Alexey Amunts SciLifeLab Fellow
SciLifeLab Data Centre
Publications 9.5.1