Normal values for calprotectin in stool samples of infants from the population-based longitudinal born into life study.

Peura S, Fall T, Almqvist C, Andolf E, Hedman A, Pershagen G, Helmersson-Karlqvist J, Larsson A

Scandinavian Journal of Clinical and Laboratory Investigation 78 (1-2) 120-124 [2017-12-28; online 2017-12-28]

Faecal calprotectin is a protein used as a diagnostic marker for inflammatory bowel diseases. We determined upper limits for normal calprotectin values for neonatal, 6, 12 and 24 months old children using a turbidimetric immunoassay in a cohort of Swedish children. The advantage of the method is that opposite to previously used enzyme-linked immunosorbent assay (ELISA) method, it enables measuring single samples, and thus, shortens the analysis time significantly. There were 72 samples (41.7% female) collected neonatally, 63 samples (34.9% female) at 6 months, 60 samples (40.0% female) at 12 months and 51 samples (43.1% female) at 24 months. The upper limits for normal values were 233, 615, 136 and 57 µg mg-1 for infants aged 0, 6, 12 and 24 months, respectively.

Affiliated researcher

Sari Peura

SciLifeLab Fellow

PubMed 29283308

DOI 10.1080/00365513.2017.1420216

Crossref 10.1080/00365513.2017.1420216

Publications 9.5.0