Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA.

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Delemotte L

J. Gen. Physiol. 150 (10) 1356-1359 [2018-10-01; online 2018-08-24]

Delemotte appraises new computational work revealing that the intracellular activation gate must open for C-type inactivation to occur in K+ channels.

Lucie Delemotte

SciLifeLab Fellow

PubMed 30143551

DOI 10.1085/jgp.201812161

Crossref 10.1085/jgp.201812161

pmc: PMC6168244
pii: jgp.201812161