Westerlund AM

Markov State Modelling Reveals Heterogeneous Drug-Inhibition Mechanism of Calmodulin

Westerlund AM, Sridhar A, Dahl L, ..., Bodnar AY, Delemotte L

- - (-) - [2022-06-09; online 2022-06-09]

Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening.

Kang PW, Westerlund AM, Shi J, ..., Delemotte L, Cui J

Sci Adv 6 (50) - [2020-12-00; online 2020-12-11]

Lucie Delemotte SciLifeLab Fellow

Tracking the motion of the KV1.2 voltage sensor reveals the molecular perturbations caused by a de novo mutation in a case of epilepsy.

Pantazis A, Kaneko M, Angelini M, ..., Saitta SC, Olcese R

J. Physiol. (Lond.) 598 (22) 5245-5269 [2020-11-00; online 2020-09-21]

Network analysis reveals how lipids and other cofactors influence membrane protein allostery.

Westerlund AM, Fleetwood O, Pérez-Conesa S, Delemotte L

J Chem Phys 153 (14) 141103 [2020-10-14; online 2020-10-23]

Lucie Delemotte SciLifeLab Fellow

Molecular insights from conformational ensembles via machine learning

Fleetwood O, Kasimova MA, Westerlund AM, Delemotte L

- - (-) - [2019-07-07; online 2019-07-07]