ST Pipeline: an automated pipeline for spatial mapping of unique transcripts.

Navarro JF, Sjöstrand J, Salmén F, Lundeberg J, Ståhl PL

Bioinformatics 33 (16) 2591-2593 [2017-08-15; online 2017-04-12]

In recent years we have witnessed an increase in novel RNA-seq based techniques for transcriptomics analysis. Spatial transcriptomics is a novel RNA-seq based technique that allows spatial mapping of transcripts in tissue sections. The spatial resolution adds an extra level of complexity, which requires the development of new tools and algorithms for efficient and accurate data processing. Here we present a pipeline to automatically and efficiently process RNA-seq data obtained from spatial transcriptomics experiments to generate datasets for downstream analysis. The ST Pipeline is open source under a MIT license and it is available at Supplementary data are available at Bioinformatics online.

Affiliated researcher

PubMed 28398467

DOI 10.1093/bioinformatics/btx211

Crossref 10.1093/bioinformatics/btx211

pii: 3111847

Publications 9.5.0