Role of Ligand-Driven Conformational Changes in Enzyme Catalysis: Modeling the Reactivity of the Catalytic Cage of Triosephosphate Isomerase.

Kulkarni YS, Liao Q, Byléhn F, Amyes TL, Richard JP, Kamerlin SCL

J. Am. Chem. Soc. 140 (11) 3854-3857 [2018-03-21; online 2018-03-13]

We have previously performed empirical valence bond calculations of the kinetic activation barriers, Δ G

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PubMed 29516737

DOI 10.1021/jacs.8b00251

Crossref 10.1021/jacs.8b00251

pmc PMC5867644