Demography and mating system shape the genome-wide impact of purifying selection inArabis alpina

Laenen B, Tedder A, Nowak MD, Toräng P, Wunder J, Wötzel S, Steige KA, Kourmpetis Y, Odong T, Drouzas AD, Bink MCAM, Ågren J, Coupland G, Slotte T

Proceedings of the National Academy of Sciences 115 (4) 816-821 [2018-01-23; online 2018-01-04]

Plant mating systems have profound effects on levels and structuring of genetic variation and can affect the impact of natural selection. Although theory predicts that intermediate outcrossing rates may allow plants to prevent accumulation of deleterious alleles, few studies have empirically tested this prediction using genomic data. Here, we study the effect of mating system on purifying selection by conducting population-genomic analyses on whole-genome resequencing data from 38 European individuals of the arctic-alpine crucifer

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PubMed 29301967

DOI 10.1073/pnas.1707492115

Crossref 10.1073/pnas.1707492115