Phosphoproteomics Reveals Regulatory T Cell-Mediated DEF6 Dephosphorylation That Affects Cytokine Expression in Human Conventional T Cells.

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Joshi RN, Binai NA, Marabita F, Sui Z, Altman A, Heck AJR, Tegnér J, Schmidt A

Front Immunol 8 (-) 1163 [2017-09-25; online 2017-09-25]

Regulatory T cells (Tregs) control key events of immune tolerance, primarily by suppression of effector T cells. We previously revealed that Tregs rapidly suppress T cell receptor (TCR)-induced calcium store depletion in conventional CD4

Affiliated researcher

PubMed 28993769

DOI 10.3389/fimmu.2017.01163

Crossref 10.3389/fimmu.2017.01163

pmc: PMC5622166