Sezgin E, Davis SJ, Eggeling C
Cell 161 (3) 433-434 [2015-04-23; online 2015-04-25]
The existence, nature, and role of highly ordered membrane domains, often referred to as lipid rafts, have been highly debated by cell biologists for many years. In this issue, Raghupathy et al. describe molecular mechanisms leading to the formation of ordered lipid-protein clusters.