Structure-metabolism-relationships in the microsomal clearance of piperazin-1-ylpyridazines.

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Llona-Minguez S, Ghassemian A, Baranczewski P, Desroses M, Koolmeister T, Artursson P, Scobie M, Helleday T

Med. Chem. Commun. 8 (7) 1553-1560 [2017-07-01; online 2017-07-04]

In this study, we provide insight into the metabolic profile of a series of piperazin-1-ylpyridazines suffering from rapid

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PubMed 30108867

DOI 10.1039/c7md00230k

Crossref 10.1039/c7md00230k

pii: c7md00230k
pmc: PMC6072423