Confounding Effects of Metformin on the Human Gut Microbiome in Type 2 Diabetes.

Mardinoglu A, Boren J, Smith U

Cell Metab. 23 (1) 10-12 [2016-01-12; online 2016-01-16]

Type 2 diabetes (T2D) is associated with dysbiosis of the gut microbiota, though diabetes treatment regimens, including metformin, may confound the results. Forslund et al. (2015) identify distinct disease and drug signatures and highlight the importance of adjusting for treatment when investigating how T2D influences the human gut microbiome.

Adil Mardinoglu

Fellows programme

PubMed 26771114

DOI 10.1016/j.cmet.2015.12.012

Crossref 10.1016/j.cmet.2015.12.012

pii: S1550-4131(15)00627-0