Daniel Globisch

Comparison of two arylsulfatases for targeted mass spectrometric analysis of microbiota-derived metabolites

Jain A, Correia MSP, Meistermann H, ..., Löhr J, Globisch D

J. Pharm. Biomed. Anal. - (-) - [2020-12-09; online 2020-12-02]

Comparative dietary sulfated metabolome analysis reveals unknown metabolic interactions of the gut microbiome and the human host.

Correia MSP, Jain A, Alotaibi W, ..., Rodriguez-Mateos A, Globisch D

pii: S0891-5849(20)31243-0

Free Radic. Biol. Med. 160 (-) 745-754 [2020-11-20; online 2020-09-11]

Amino Acid Modified RNA Bases as Building Blocks of an Early Earth RNA-Peptide World.

Nainytė M, Müller F, Ganazzoli G, ..., Globisch D, Carell T

Chemistry 26 (65) 14856-14860 [2020-11-20; online 2020-10-14]

Rapid Preparation of a Large Sulfated Metabolite Library for Structure Validation in Human Samples.

Correia MSP, Lin W, Aria AJ, Jain A, Globisch D

pii: metabo10100415 pmc: PMC7603051

Metabolites 10 (10) - [2020-10-16; online 2020-10-16]

Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine N-Acetyltransferase NAT2.

Conway LP, Rendo V, Correia MSP, ..., Sjöblom T, Globisch D

pmc: PMC7497018

Angew. Chem. Int. Ed. Engl. 59 (34) 14342-14346 [2020-08-17; online 2020-07-08]

DNA surface exploration and operator bypassing during target search

Marklund E, van Oosten B, Mao G, ..., Elf J, Deindl S

Nature 583 (7818) 858-861 [2020-07-30; online 2020-06-24]

Daniel Globisch Sebastian Deindl

Sensitive mass spectrometric analysis of carbonyl metabolites in human urine and fecal samples using chemoselective modification.

Lin W, Conway LP, Block A, ..., Löhr JM, Globisch D

Analyst 145 (11) 3822-3831 [2020-06-07; online 2020-05-12]

Year 2019

Chemoselective probe for detailed analysis of ketones and aldehydes produced by gut microbiota in human samples.

Conway LP, Garg N, Lin W, ..., Löhr JM, Globisch D

Chem. Commun. (Camb.) 55 (62) 9080-9083 [2019-08-11; online 2019-07-09]

Coupled Enzymatic Treatment and Mass Spectrometric Analysis for Identification of Glucuronidated Metabolites in Human Samples.

Correia MSP, Rao M, Ballet C, Globisch D

Chembiochem 20 (13) 1678-1683 [2019-07-01; online 2019-05-08]

Comprehensive kinetic and substrate specificity analysis of an arylsulfatase from Helix pomatia using mass spectrometry.

Correia MSP, Ballet C, Meistermann H, Conway LP, Globisch D

pii: S0968-0896(18)32030-3

Bioorg. Med. Chem. 27 (6) 955-962 [2019-03-15; online 2019-01-30]

Year 2018

Chemoselective Probe Containing a Unique Bioorthogonal Cleavage Site for Investigation of Gut Microbiota Metabolism.

Garg N, Conway LP, Ballet C, ..., Löhr JM, Globisch D

Angew. Chem. Int. Ed. Engl. 57 (42) 13805-13809 [2018-10-15; online 2018-09-20]

Noninvasive Urine Biomarker Lateral Flow Immunoassay for Monitoring Active Onchocerciasis.

Shirey RJ, Globisch D, Eubanks LM, Hixon MS, Janda KD

pmc: PMC6189908

ACS Infect Dis 4 (10) 1423-1431 [2018-10-12; online 2018-09-21]

New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites.

Ballet C, Correia MSP, Conway LP, ..., Löhr JM, Globisch D

pii: c8sc01502c pmc: PMC6063053

Chem Sci 9 (29) 6233-6239 [2018-08-07; online 2018-06-28]

Affiliated researcher Daniel Globisch Sebastian Deindl

Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control

Garg N, Hansson A, Knych HK, ..., Hedeland M, Globisch D

Org. Biomol. Chem. 16 (5) 698-702 [2018-00-00; online 2018-00-00]

Affiliated researcher Daniel Globisch

Year 2017

Validation of onchocerciasis biomarker N -acetyltyramine- O -glucuronide (NATOG)

Globisch D, Eubanks LM, Shirey RJ, ..., Hoerauf A, Janda KD

Bioorganic & Medicinal Chemistry Letters 27 (15) 3436-3440 [2017-08-00; online 2017-08-00]

Affiliated researcher Daniel Globisch

Year 2016

Glycation Reactivity of a Quorum-Sensing Signaling Molecule

Tsuchikama K, Gooyit M, Harris TL, ..., Kaufmann GF, Janda KD

Angewandte Chemie International Edition 55 (12) 4002-4006 [2016-03-14; online 2016-02-17]

Year 2015

Litomosoides sigmodontis: A jird urine metabolome study

Globisch D, Specht S, Pfarr KM, ..., Hoerauf A, Janda KD

Bioorganic & Medicinal Chemistry Letters 25 (24) 5804-5807 [2015-12-00; online 2015-12-00]

A chemoenzymatic approach toward the preparation of site-specific antibody–drug conjugates

Cai X, Janda KD

Tetrahedron Letters 56 (23) 3172-3175 [2015-06-00; online 2015-06-00]

Flagellin as Carrier and Adjuvant in Cocaine Vaccine Development

Lockner JW, Eubanks LM, Choi JL, ..., Wilson IA, Janda KD

Mol. Pharmaceutics 12 (2) 653-662 [2015-02-02; online 2015-01-07]

Year 2013

Mechanistic Insights into the LsrK Kinase Required for Autoinducer-2 Quorum Sensing Activation

Zhu J, Hixon MS, Globisch D, Kaufmann GF, Janda KD

J. Am. Chem. Soc. 135 (21) 7827-7830 [2013-05-29; online 2013-05-16]

Onchocerca volvulus-neurotransmitter tyramine is a biomarker for river blindness

Globisch D, Moreno AY, Hixon MS, ..., Hoerauf A, Janda KD

Proceedings of the National Academy of Sciences 110 (11) 4218-4223 [2013-03-12; online 2013-02-25]

Year 2012

Isotope-Based Analysis of Modified tRNA Nucleosides Correlates Modification Density with Translational Efficiency

Brandmayr C, Wagner M, Brückl T, ..., Biel M, Carell T

Angewandte Chemie International Edition 51 (44) 11162-11165 [2012-10-29; online 2012-10-04]

Low values of 5-hydroxymethylcytosine (5hmC), the “sixth base,” are associated with anaplasia in human brain tumors

Kraus TFJ, Globisch D, Wagner M, ..., Carell T, Kretzschmar HA

Int. J. Cancer 131 (7) 1577-1590 [2012-10-01; online 2012-03-02]

The CDK5 repressor CDK5RAP1 is a methylthiotransferase acting on nuclear and mitochondrial RNA

Reiter V, Matschkal DMS, Wagner M, ..., Müller M, Carell T

Nucleic Acids Res. 40 (13) 6235-6240 [2012-07-00; online 2012-03-15]

Uncharacterized 4,5-Dihydroxy-2,3-Pentanedione (DPD) Molecules Revealed Through NMR Spectroscopy: Implications for a Greater Signaling Diversity in Bacterial Species

Globisch D, Lowery CA, McCague KC, Janda KD

Angewandte Chemie International Edition 51 (17) 4204-4208 [2012-04-23; online 2012-02-29]

Year 2011

Formulating a new basis for the treatment against botulinum neurotoxin intoxication: 3,4-Diaminopyridine prodrug design and characterization

Zakhari JS, Kinoyama I, Hixon MS, ..., Globisch D, Janda KD

Bioorganic & Medicinal Chemistry 19 (21) 6203-6209 [2011-11-00; online 2011-11-00]

Systems-Based Analysis of Modified tRNA Bases

Globisch D, Pearson D, Hienzsch A, ..., Sieber SA, Carell T

Angewandte Chemie International Edition 50 (41) 9739-9742 [2011-10-04; online 2011-08-31]

5-Hydroxymethylcytosine, the Sixth Base of the Genome

Münzel M, Globisch D, Carell T

Angewandte Chemie International Edition 50 (29) 6460-6468 [2011-07-11; online 2011-06-17]

Discovery and Synthesis of New UV-Induced Intrastrand C(4−8)G and G(8−4)C Photolesions

Münzel M, Szeibert C, Glas AF, Globisch D, Carell T

J. Am. Chem. Soc. 133 (14) 5186-5189 [2011-04-13; online 2011-04-13]

LC-MS based quantification of 2′-ribosylated nucleosides Ar(p) and Gr(p) in tRNA

Pearson D, Hienzsch A, Wagner M, ..., Özden D, Carell T

Chem. Commun. 47 (18) 5196 [2011-00-00; online 2011-00-00]

Year 2010

Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates

Globisch D, Münzel M, Müller M, ..., Biel M, Carell T

PLoS ONE 5 (12) e15367 [2010-12-23; online 2010-12-23]

Efficient Synthesis of 5-Hydroxymethylcytosine Containing DNA

Münzel M, Globisch D, Trindler C, Carell T

Org. Lett. 12 (24) 5671-5673 [2010-12-17; online 2010-12-17]

A Novel Synthetic Route for the Anti-HIV Drug MC-1220 and its Analogues

Loksha YM, Globisch D, Loddo R, ..., La Colla P, Pedersen EB

ChemMedChem 5 (11) 1847-1849 [2010-11-08; online 2010-08-16]

Quantification of the Sixth DNA Base Hydroxymethylcytosine in the Brain

Münzel M, Globisch D, Brückl T, ..., Biel M, Carell T

Angewandte Chemie International Edition 49 (31) 5375-5377 [2010-06-25; online 2010-06-25]

Year 2009

Parallel isotope-based quantification of modified tRNA nucleosides.

Brückl T, Globisch D, Wagner M, Müller M, Carell T

Angew. Chem. Int. Ed. Engl. 48 (42) 7932-7934 [2009-09-12; online 2009-09-12]

Synthesis and anti‐HIV‐1 evaluation of 1,5‐disubstituted pyrimidine‐2,4‐diones

Loksha YM, Globisch D, Pedersen EB, ..., Collu G, Loddo R

J. Heterocyclic Chem. 45 (-) 1161-1166 [2009-03-13; online 2009-03-13]

Year 2008

Stability ofHoogsteen-Type Triplexes – Electrostatic Attraction between Duplex Backbone and Triplex-Forming Oligonucleotide (TFO) Using an Intercalating Conjugate

Globisch D, Bomholt N, Filichev VV, Pedersen EB

HCA 91 (5) 805-818 [2008-05-00; online 2008-05-00]