Kutter C

Intrinsic deletion at 10q23.31, including the PTEN gene locus, is aggravated upon CRISPR-Cas9-mediated genome engineering in HAP1 cells mimicking cancer profiles.

Geng K, Merino LG, Veiga RG, ..., Brinkman EK, Kutter C

Life Sci. Alliance 7 (2) - [2024-02-00; online 2023-11-20]

Coinhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription.

Cameron DP, Grosser J, Ladigan S, ..., Hahn SA, Baranello L

Sci Adv 9 (41) eadg5109 [2023-10-13; online 2023-10-13]

Estrogen receptor activation remodelsTEAD1gene expression to alleviate nonalcoholic fatty liver disease

Sommerauer C, Gallardo-Dodd CJ, Savva C, ..., Williams C, Kutter C

- - (-) - [2023-09-08; online 2023-09-08]

Exposure of volunteers to microgravity by dry immersion bed over 21 days results in gene expression changes and adaptation of T cells.

Gallardo-Dodd CJ, Oertlin C, Record J, ..., Ponomarev SA, Westerberg LS

Sci Adv 9 (34) eadg1610 [2023-08-25; online 2023-08-25]

CRISPR-Cas9-mediated genome engineering exaggerates genomic deletion at 10q23.31 including the<i>PTEN</i>gene locus mimicking cancer profiles

Geng K, Merino LG, Veiga RG, ..., Brinkman EK, Kutter C

- - (-) - [2023-04-06; online 2023-04-06]

Molecular programming modulates hepatic lipid metabolism and adult metabolic risk in the offspring of obese mothers in a sex-specific manner.

Savva C, Helguero LA, González-Granillo M, ..., Kutter C, Korach-André M

Commun Biol 5 (1) 1057 [2022-10-04; online 2022-10-04]

Noncoding RNAs and RNA-binding proteins: emerging governors of liver physiology and metabolic diseases.

Sommerauer C, Kutter C

Am. J. Physiol., Cell Physiol. 323 (4) C1003-C1017 [2022-10-01; online 2022-08-15]

Target-enriched nanopore sequencing and de novo assembly reveals co-occurrences of complex on-target genomic rearrangements induced by CRISPR-Cas9 in human cells.

Geng K, Merino LG, Wedemann L, ..., White RJ, Kutter C

Genome Res 32 (10) 1876-1891 [2022-10-00; online 2022-09-30]

Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation.

Zhu K, Wang Y, Sarlus H, ..., Högberg B, Harris RA

EMBO Rep. 23 (7) e54499 [2022-07-05; online 2022-05-20]

ZFP207 sustains pluripotency by coordinating OCT4 stability, alternative splicing and RNA export.

Malla S, Prasad Bhattarai D, Groza P, ..., Kutter C, Aguilo F

EMBO Rep. 23 (3) e53191 [2022-02-03; online 2022-01-17]

CCT3-LINC00326 axis regulates hepatocarcinogenic lipid metabolism.

Søndergaard JN, Sommerauer C, Atanasoai I, ..., Barragan I, Kutter C

Gut 71 (10) 2081-2092 [2022-01-12; online 2022-01-12]

Cell type-specific analysis by single-cell profiling identifies a stable mammalian tRNA-mRNA interface and increased translation efficiency in neurons.

Gao W, Gallardo-Dodd CJ, Kutter C

Genome Res 32 (1) 97-110 [2022-01-00; online 2021-12-02]

Large-scale identification of RBP-RNA interactions by RAPseq refines essentials of post-transcriptional gene regulation

Atanasoai I, Papavasileiou S, Preiß N, Kutter C

- - (-) - [2021-11-09; online 2021-11-09]

ZFP207 <i>controls pluripotency by multiple post-transcriptional mechanisms</i>

Malla S, Bhattarai DP, Melguizo-Sanchis D, ..., Kutter C, Aguilo F

- - (-) - [2021-03-02; online 2021-03-02]

Obese mother offspring have hepatic lipidic modulation that contributes to sex-dependent metabolic adaptation later in life.

Savva C, Helguero LA, González-Granillo M, ..., Kutter C, Korach-André M

Commun Biol 4 (1) 14 [2021-01-04; online 2021-01-04]

JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality.

Stebbing J, Sánchez Nievas G, Falcone M, ..., Abizanda P, Lauschke VM

Sci Adv 7 (1) - [2021-01-00; online 2021-01-01]