Biophys. J.

Unraveling the conformational landscape of amyloid precursor protein intracellular domain.

Mandal N, Skepö M

Biophys. J. 124 (21) 3527-3541 [2025-11-04; online 2025-08-14]

Year 2024

Cryo-EM images of phase-separated lipid bilayer vesicles analyzed with a machine-learning approach.

Sharma KD, Doktorova M, Waxham MN, Heberle FA

Biophys. J. 123 (17) 2877-2891 [2024-09-03; online 2024-04-30]

Quantification of membrane fluidity in bacteria using TIR-FCS.

Barbotin A, Billaudeau C, Sezgin E, Carballido-López R

Biophys. J. 123 (16) 2484-2495 [2024-08-20; online 2024-06-13]

An intracellular hydrophobic nexus critical for hERG1 channel slow deactivation.

Stevens-Sostre WA, Flores-Aldama L, Bustos D, ..., Delemotte L, Robertson GA

Biophys. J. 123 (14) 2024-2037 [2024-07-16; online 2024-01-12]

Lucie Delemotte SciLifeLab Fellow

Mapping the contribution of the C-linker domain to gating polarity in CNBD channels.

Lin JL, Chang Y, Tewari D, Cowgill J, Chanda B

Biophys. J. 123 (14) 2176-2184 [2024-07-16; online 2024-04-27]

Neural network informed photon filtering reduces fluorescence correlation spectroscopy artifacts.

Seltmann A, Carravilla P, Reglinski K, Eggeling C, Waithe D

Biophys. J. 123 (6) 745-755 [2024-03-19; online 2024-02-20]

Year 2023

Building the next generation of virtual cells to understand cellular biology.

Johnson GT, Agmon E, Akamatsu M, ..., Rafelski S, Horwitz R

Biophys. J. 122 (18) 3560-3569 [2023-09-19; online 2023-04-11]

Automated simulation-based membrane protein refinement into cryo-EM data.

Yvonnesdotter L, Rovšnik U, Blau C, ..., Howard RJ, Lindahl E

Biophys. J. 122 (13) 2773-2781 [2023-07-11; online 2023-06-05]

Membranes in focus.

Sezgin E, Levental I

Biophys. J. - (-) - [2023-05-19; online 2023-05-19]

Molecular simulations and NMR reveal how lipid fluctuations affect membrane mechanics.

Doktorova M, Khelashvili G, Ashkar R, Brown MF

Biophys. J. 122 (6) 984-1002 [2023-03-21; online 2022-12-05]

Year 2022

Measuring single-virus fusion kinetics using an assay for nucleic acid exposure.

Villamil Giraldo AM, Mannsverk S, Kasson PM

Biophys. J. 121 (23) 4467-4475 [2022-12-06; online 2022-11-09]

Skin permeability prediction with MD simulation sampling spatial and alchemical reaction coordinates.

Lundborg M, Wennberg C, Lidmar J, ..., Lindahl E, Norlén L

Biophys. J. 121 (20) 3837-3849 [2022-10-18; online 2022-09-13]

Influence of the extracellular domain size on the dynamic behavior of membrane proteins.

Gurdap CO, Wedemann L, Sych T, Sezgin E

Biophys. J. 121 (20) 3826-3836 [2022-10-18; online 2022-09-14]

Cholesterol's balancing act: Defying the status quo.

Doktorova M, Levental I

Biophys. J. 121 (20) 3771-3773 [2022-10-18; online 2022-08-30]

Transition between conformational states of the TREK-1 K2P channel promoted by interaction with PIP2.

Panasawatwong A, Pipatpolkai T, Tucker SJ

Biophys. J. 121 (12) 2380-2388 [2022-06-21; online 2022-05-19]

An open state of a voltage-gated sodium channel involving a π-helix and conserved pore-facing asparagine.

Choudhury K, Kasimova MA, McComas S, Howard RJ, Delemotte L

Biophys. J. 121 (1) 11-22 [2022-01-04; online 2021-12-08]

Lucie Delemotte SciLifeLab Fellow

Year 2021

Vesicle Viewer: Online visualization and analysis of small-angle scattering from lipid vesicles.

Lewis-Laurent A, Doktorova M, Heberle FA, Marquardt D

Biophys. J. 120 (21) 4639-4648 [2021-11-02; online 2021-09-24]

Ca2+-dependent mechanism of membrane insertion and destabilization by the SARS-CoV-2 fusion peptide.

Khelashvili G, Plante A, Doktorova M, Weinstein H

Biophys. J. 120 (6) 1105-1119 [2021-03-16; online 2021-02-23]

Year 2020

Pulsed Electric Fields Can Create Pores in the Voltage Sensors of Voltage-Gated Ion Channels.

Rems L, Kasimova MA, Testa I, Delemotte L

Biophys. J. 119 (1) 190-205 [2020-07-07; online 2020-06-08]

Ilaria Testa Lucie Delemotte SciLifeLab Fellow

z-STED Imaging and Spectroscopy to Investigate Nanoscale Membrane Structure and Dynamics.

Barbotin A, Urbančič I, Galiani S, ..., Booth M, Sezgin E

Biophys. J. 118 (10) 2448-2457 [2020-05-19; online 2020-04-16]

Molecular Insights from Conformational Ensembles via Machine Learning.

Fleetwood O, Kasimova MA, Westerlund AM, Delemotte L

Biophys. J. 118 (3) 765-780 [2020-02-04; online 2019-12-21]

Lucie Delemotte SciLifeLab Fellow

On the Long and Winding Road to a Perfect Membrane Model.

Doktorova M

Biophys. J. 118 (2) 273-275 [2020-01-21; online 2019-11-28]

Year 2019

Detecting and Controlling Dye Effects in Single-Virus Fusion Experiments.

Rawle RJ, Villamil Giraldo AM, Boxer SG, Kasson PM

Biophys. J. 117 (3) 445-452 [2019-08-06; online 2019-07-02]

Gramicidin Increases Lipid Flip-Flop in Symmetric and Asymmetric Lipid Vesicles.

Doktorova M, Heberle FA, Marquardt D, ..., Weinstein H, Andersen OS

Biophys. J. 116 (5) 860-873 [2019-03-05; online 2019-01-25]

A New Computational Method for Membrane Compressibility: Bilayer Mechanical Thickness Revisited.

Doktorova M, LeVine MV, Khelashvili G, Weinstein H

Biophys. J. 116 (3) 487-502 [2019-02-05; online 2019-01-03]

GROmaρs: A GROMACS-Based Toolset to Analyze Density Maps Derived from Molecular Dynamics Simulations.

Briones R, Blau C, Kutzner C, de Groot BL, Aponte-Santamaría C

Biophys. J. 116 (1) 4-11 [2019-01-08; online 2018-12-01]

Year 2018

Accurate In Silico Modeling of Asymmetric Bilayers Based on Biophysical Principles.

Doktorova M, Weinstein H

Biophys. J. 115 (9) 1638-1643 [2018-11-06; online 2018-09-15]

Structural Transitions in Ceramide Cubic Phases during Formation of the Human Skin Barrier.

Wennberg CL, Narangifard A, Lundborg M, Norlén L, Lindahl E

Biophys. J. 114 (5) 1116-1127 [2018-03-13; online 2018-03-15]

Affiliated researcher

Year 2017

Cholesterol Promotes Protein Binding by Affecting Membrane Electrostatics and Solvation Properties.

Doktorova M, Heberle FA, Kingston RL, ..., Vogt VM, Dick RA

Biophys. J. 113 (9) 2004-2015 [2017-11-07; online 2017-11-09]

Polarity-Sensitive Probes for Superresolution Stimulated Emission Depletion Microscopy.

Sezgin E, Schneider F, Zilles V, ..., Klymchenko AS, Eggeling C

Biophys. J. 113 (6) 1321-1330 [2017-09-19; online 2017-07-19]

Year 2016

Membrane Anchoring and Ion-Entry Dynamics in P-type ATPase Copper Transport.

Grønberg C, Sitsel O, Lindahl E, Gourdon P, Andersson M

Biophys. J. 111 (11) 2417-2429 [2016-12-06; online 2016-12-08]

Affiliated researcher

Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy.

Steshenko O, Andrade DM, Honigmann A, ..., Simons M, Eggeling C

Biophys. J. 110 (11) 2441-2450 [2016-06-07; online 2016-06-09]

Year 2013

Local partition coefficients govern solute permeability of cholesterol-containing membranes.

Zocher F, van der Spoel D, Pohl P, Hub JS

Biophys. J. 105 (12) 2760-2770 [2013-12-17; online 2013-12-24]

Stabilization of the GluCl ligand-gated ion channel in the presence and absence of ivermectin.

Yoluk O, Brömstrup T, Bertaccini EJ, Trudell JR, Lindahl E

Biophys. J. 105 (3) 640-647 [2013-08-06; online 2013-08-13]

The conserved phenylalanine in the K+ channel voltage-sensor domain creates a barrier with unidirectional effects.

Schwaiger CS, Liin SI, Elinder F, Lindahl E

Biophys. J. 104 (1) 75-84 [2013-01-08; online 2013-01-08]

Year 2008

Picosecond fluorescence of intact and dissolved PSI-LHCI crystals.

van Oort B, Amunts A, Borst JW, ..., van Amerongen H, Croce R

Biophys. J. 95 (12) 5851-5861 [2008-12-15; online 2008-10-17]

Alexey Amunts SciLifeLab Fellow