Pelechano V

A streamlined nanopore-compatible 5PSeq protocol for rapid phenotypic antimicrobial sensitivity testing

Liu H, Huch S, Hull R, ..., Du J, Pelechano V

- - (-) - [2025-11-12; online 2025-11-12]

A U3 snoRNA is required for the regulation of chromatin dynamics and antiviral response in Drosophila melanogaster.

Jain S, Planells J, Regadas I, ..., Mannervik M, Visa N

Nucleic Acids Res. 53 (14) - [2025-07-19; online 2025-07-30]

XRN1 supplies free nucleotides to feed alphavirus replication

Ruscica V, Iselin L, Hull R, ..., Davis I, Castello A

- - (-) - [2024-12-09; online 2024-12-09]

The early transcriptional and post-transcriptional responses to fluconazole in sensitive and resistant Candida albicans.

Stevens I, Silao FG, Huch S, ..., Ljungdahl PO, Pelechano V

Sci Rep 14 (1) 29012 [2024-11-22; online 2024-11-22]

The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site.

Turnbull K, Paternoga H, von der Weth E, ..., Wilson DN, Hauryliuk V

Nucleic Acids Res. 52 (19) 12005-12020 [2024-10-28; online 2024-09-01]

Author Correction: Gene-expression memory-based prediction of cell lineages from scRNA-seq datasets.

Eisele AS, Tarbier M, Dormann AA, Pelechano V, Suter DM

Nat Commun 15 (1) 4752 [2024-06-04; online 2024-06-04]

The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site.

Turnbull K, Paternoga H, von der Weth E, ..., Wilson DN, Hauryliuk V

bioRxiv - (-) - [2024-05-29; online 2024-05-29]

Cellular energy regulates mRNA degradation in a codon-specific manner.

Tomaz da Silva P, Zhang Y, Theodorakis E, ..., Pelechano V, Gagneur J

Mol Syst Biol 20 (5) 506-520 [2024-05-00; online 2024-03-15]

Gene-expression memory-based prediction of cell lineages from scRNA-seq datasets.

Eisele AS, Tarbier M, Dormann AA, Pelechano V, Suter DM

Nat Commun 15 (1) 2744 [2024-03-29; online 2024-03-29]

DDLS Fellow Marcel Tarbier

Ribosomes modulate transcriptome abundance via generalized frameshift and out-of-frame mRNA decay

Zhang Y, Nersisyan L, Fürst E, ..., Piazza I, Pelechano V

- - (-) - [2024-03-12; online 2024-03-12]

The association of the RSC remodeler complex with chromatin is influenced by the prefoldin-like Bud27 and determines nucleosome positioning and polyadenylation sites usage in Saccharomyces cerevisiae.

Cuevas-Bermúdez A, Martínez-Fernández V, Garrido-Godino AI, ..., Pelechano V, Navarro F

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1867 (1) 194995 [2024-03-00; online 2023-11-13]

Digital assay for rapid electronic quantification of clinical pathogens using DNA nanoballs.

Tayyab M, Barrett D, van Riel G, ..., Javanmard M, Pelechano V

Sci Adv 9 (36) eadi4997 [2023-09-08; online 2023-09-06]

Atlas of mRNA translation and decay for bacteria.

Huch S, Nersisyan L, Ropat M, ..., Engstrand L, Pelechano V

Nat. Microbiol - (-) - [2023-05-22; online 2023-05-22]

The association of the RSC remodeler complex with chromatin depends on prefoldin-like Bud27 and determines nucleosome positioning and polyadenylation sites usage in Saccharomyces cerevisiae

Cuevas-Bermúdez A, Martínez-Fernández V, Garrido-Godino AI, ..., Pelechano V, Navarro F

- - (-) - [2023-03-21; online 2023-03-21]

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling.

Altea-Manzano P, Doglioni G, Liu Y, ..., Malanchi I, Fendt SM

Nat Cancer 4 (3) 344-364 [2023-03-00; online 2023-02-02]

Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation.

Li B, Zeis P, Zhang Y, ..., Steinmetz LM, Pelechano V

Nat Commun 14 (1) 910 [2023-02-17; online 2023-02-17]

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation

Altea-Manzano P, Doglioni G, Cuadros AM, ..., Malanchi I, Fendt SM

- - (-) - [2022-10-24; online 2022-10-24]

Barcode-free prediction of cell lineages from scRNA-seq datasets

Eisele AS, Tarbier M, Dormann AA, Pelechano V, Suter DM

- - (-) - [2022-09-20; online 2022-09-20]

OPUSeq simplifies detection of low-frequency DNA variants and uncovers fragmentase-associated artifacts.

Alekseenko A, Wang J, Barrett D, Pelechano V

NAR Genomics and Bioinformatics 4 (2) lqac048 [2022-06-00; online 2022-06-27]

Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation

Li B, Zeis P, Alekseenko A, ..., Steinmetz LM, Pelechano V

- - (-) - [2022-05-05; online 2022-05-05]

Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.

Crowe-McAuliffe C, Murina V, Turnbull KJ, ..., Wilson DN, Hauryliuk V

Nat Commun 13 (1) 1860 [2022-04-06; online 2022-04-06]

Sample-to-answer COVID-19 nucleic acid testing using a low-cost centrifugal microfluidic platform with bead-based signal enhancement and smartphone read-out.

Soares RRG, Akhtar AS, Pinto IF, ..., Pelechano V, Russom A

Lab Chip 21 (15) 2932-2944 [2021-08-07; online 2021-06-11]

Rpb4 and Puf3 imprint and post-transcriptionally control the stability of a common set of mRNAs in yeast.

Garrido-Godino AI, Gupta I, Gutiérrez-Santiago F, ..., Pelechano V, Navarro F

RNA Biol 18 (8) 1206-1220 [2021-08-00; online 2020-11-01]

Simultaneous detection of SARS-CoV-2 and pandemic (H1N1) 2009 virus with real-time isothermal platform.

Yu L, Wang J, Li X, ..., Guo X, Yin X

Heliyon 7 (7) e07584 [2021-07-00; online 2021-07-15]

High-throughput 5′P sequencing enables the study of degradation-associated ribosome stalls

Zhang Y, Pelechano V

Cell Rep Methods 1 (1) 100001 [2021-05-00; online 2021-05-00]

RNA degradation analysis reveals ribosome dynamics in complex microbiome samples

Huch S, Nersisyan L, Ropat M, ..., Engstrand L, Pelechano V

- - (-) - [2021-04-10; online 2021-04-10]

Direct detection of SARS-CoV-2 using non-commercial RT-LAMP reagents on heat-inactivated samples.

Alekseenko A, Barrett D, Pareja-Sanchez Y, ..., Yin X, Pelechano V

Sci Rep 11 (1) 1820 [2021-01-19; online 2021-01-19]

SciLifeLab Fellow Simon Elsässer Vicent Pelechano

Improved computational analysis of ribosome dynamics from 5′P degradome data using fivepseq

Nersisyan L, Ropat M, Pelechano V

NAR Genomics and Bioinformatics 2 (4) - [2020-11-24; online 2020-11-24]

Point-of-care detection of SARS-CoV-2 in nasopharyngeal swab samples using an integrated smartphone-based centrifugal microfluidic platform

Soares RRG, Akhtar AS, Pinto IF, ..., Pelechano V, Russom A

- - (-) - [2020-11-06; online 2020-11-06]

TIF-Seq2 disentangles overlapping isoforms in complex human transcriptomes.

Wang J, Li B, Marques S, ..., Wei W, Pelechano V

Nucleic Acids Res. 48 (18) e104 [2020-10-09; online 2020-08-21]

The RNA exosome shapes the expression of key protein-coding genes.

Wu M, Karadoulama E, Lloret-Llinares M, ..., Jensen TH, Sandelin A

Nucleic Acids Res. 48 (15) 8509-8528 [2020-09-04; online 2020-07-28]

Detection of SARS-CoV-2 using non-commercial RT-LAMP reagents and raw samples

Alekseenko A, Barrett D, Pareja-Sanchez Y, ..., Yin X, Pelechano V

- - (-) - [2020-08-24; online 2020-08-24]

High-throughput 5’P sequencing enables the study of degradation-associated ribosome stalls

Zhang Y, Pelechano V

- - (-) - [2020-06-23; online 2020-06-23]

Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis.

Thomas QA, Ard R, Liu J, ..., Pelechano V, Marquardt S

Nat Commun 11 (1) 2589 [2020-05-22; online 2020-05-22]

Improved computational analysis of ribosome dynamics from 5’P degradome data using fivepeseq

Nersisyan L, Ropat M, Pelechano V

- - (-) - [2020-01-23; online 2020-01-23]

Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.

Wei W, Hennig BP, Wang J, ..., Steinmetz LM, Pelechano V

Genome Res 29 (12) 1974-1984 [2019-12-00; online 2019-11-18]

Dissecting chronic myeloid leukaemia overlapping transcriptome with TIF-Seq2

Wang J, Li B, Marques S, ..., Wei W, Pelechano V

- - (-) - [2019-11-29; online 2019-11-29]

Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination

Ard R, Thomas Q, Li B, ..., Pelechano V, Marquardt S

- - (-) - [2019-10-28; online 2019-10-28]

The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock.

Garre E, Pelechano V, Sánchez Del Pino M, Alepuz P, Sunnerhagen P

PLoS Genet 14 (7) e1007563 [2018-07-00; online 2018-07-30]

Affiliated researcher SciLifeLab Fellow Vicent Pelechano

Transcription-driven Chromatin Repression of Intragenic Promoters

Nielsen M, Ard R, Leng X, ..., Pelechano V, Marquardt S

- - (-) - [2018-03-09; online 2018-03-09]

From transcriptional complexity to cellular phenotypes: Lessons from yeast.

Pelechano V

Yeast 34 (12) 475-482 [2017-12-00; online 2017-10-11]

Affiliated researcher SciLifeLab Fellow Vicent Pelechano

Genome-wide quantification of 5'-phosphorylated mRNA degradation intermediates for analysis of ribosome dynamics.

Pelechano V, Wei W, Steinmetz LM

Nat Protoc 11 (2) 359-376 [2016-02-00; online 2016-01-28]