Pelechano V

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Family name Pelechano
Given name Vicent
Initials V
ORCID

ORCID 0000-0002-9415-788X
Affiliations SciLifeLab, Department of Microbiology, Tumor and Cell Biology. Karolinska Institutet, Solna 171 65, Sweden

44 publications

DOI Crossref
A streamlined nanopore-compatible 5PSeq protocol for rapid phenotypic antimicrobial sensitivity testing
Liu H, Huch S, Hull R, ..., Du J, Pelechano V
- - (-) - [2025-11-12; online 2025-11-12]
SciLifeLab Fellow
PubMed DOI Crossref
A U3 snoRNA is required for the regulation of chromatin dynamics and antiviral response in Drosophila melanogaster.
Jain S, Planells J, Regadas I, ..., Mannervik M, Visa N
Nucleic Acids Res. 53 (14) - [2025-07-19; online 2025-07-30]
DOI Crossref
XRN1 supplies free nucleotides to feed alphavirus replication
Ruscica V, Iselin L, Hull R, ..., Davis I, Castello A
- - (-) - [2024-12-09; online 2024-12-09]
SciLifeLab Fellow
PubMed DOI Crossref
The early transcriptional and post-transcriptional responses to fluconazole in sensitive and resistant Candida albicans.
Stevens I, Silao FG, Huch S, ..., Ljungdahl PO, Pelechano V
Sci Rep 14 (1) 29012 [2024-11-22; online 2024-11-22]
SciLifeLab Fellow
PubMed DOI Crossref
The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site.
Turnbull K, Paternoga H, von der Weth E, ..., Wilson DN, Hauryliuk V
Nucleic Acids Res. 52 (19) 12005-12020 [2024-10-28; online 2024-09-01]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Author Correction: Gene-expression memory-based prediction of cell lineages from scRNA-seq datasets.
Eisele AS, Tarbier M, Dormann AA, Pelechano V, Suter DM
Nat Commun 15 (1) 4752 [2024-06-04; online 2024-06-04]
DDLS Fellow Marcel Tarbier SciLifeLab Fellow
PubMed DOI Crossref
The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site.
Turnbull K, Paternoga H, von der Weth E, ..., Wilson DN, Hauryliuk V
bioRxiv - (-) - [2024-05-29; online 2024-05-29]
SciLifeLab Fellow
PubMed DOI Crossref
Cellular energy regulates mRNA degradation in a codon-specific manner.
Tomaz da Silva P, Zhang Y, Theodorakis E, ..., Pelechano V, Gagneur J
Mol Syst Biol 20 (5) 506-520 [2024-05-00; online 2024-03-15]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Gene-expression memory-based prediction of cell lineages from scRNA-seq datasets.
Eisele AS, Tarbier M, Dormann AA, Pelechano V, Suter DM
Nat Commun 15 (1) 2744 [2024-03-29; online 2024-03-29]
DDLS Fellow Marcel Tarbier SciLifeLab Fellow
DOI Crossref
Ribosomes modulate transcriptome abundance via generalized frameshift and out-of-frame mRNA decay
Zhang Y, Nersisyan L, Fürst E, ..., Piazza I, Pelechano V
- - (-) - [2024-03-12; online 2024-03-12]
SciLifeLab Fellow
PubMed DOI Crossref
The association of the RSC remodeler complex with chromatin is influenced by the prefoldin-like Bud27 and determines nucleosome positioning and polyadenylation sites usage in Saccharomyces cerevisiae.
Cuevas-Bermúdez A, Martínez-Fernández V, Garrido-Godino AI, ..., Pelechano V, Navarro F
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1867 (1) 194995 [2024-03-00; online 2023-11-13]
SciLifeLab Fellow
PubMed DOI Crossref
Digital assay for rapid electronic quantification of clinical pathogens using DNA nanoballs.
Tayyab M, Barrett D, van Riel G, ..., Javanmard M, Pelechano V
Sci Adv 9 (36) eadi4997 [2023-09-08; online 2023-09-06]
SciLifeLab Fellow
PubMed DOI Crossref
Atlas of mRNA translation and decay for bacteria.
Huch S, Nersisyan L, Ropat M, ..., Engstrand L, Pelechano V
Nat. Microbiol 8 (6) 1123-1136 [2023-06-00; online 2023-05-22]
SciLifeLab Fellow
DOI Crossref
The association of the RSC remodeler complex with chromatin depends on prefoldin-like Bud27 and determines nucleosome positioning and polyadenylation sites usage in Saccharomyces cerevisiae
Cuevas-Bermúdez A, Martínez-Fernández V, Garrido-Godino AI, ..., Pelechano V, Navarro F
- - (-) - [2023-03-21; online 2023-03-21]
SciLifeLab Fellow
PubMed DOI Crossref
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling.
Altea-Manzano P, Doglioni G, Liu Y, ..., Malanchi I, Fendt SM
Nat Cancer 4 (3) 344-364 [2023-03-00; online 2023-02-02]
SciLifeLab Fellow
PubMed DOI Crossref
Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation.
Li B, Zeis P, Zhang Y, ..., Steinmetz LM, Pelechano V
Nat Commun 14 (1) 910 [2023-02-17; online 2023-02-17]
SciLifeLab Fellow
DOI Crossref
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation
Altea-Manzano P, Doglioni G, Cuadros AM, ..., Malanchi I, Fendt SM
- - (-) - [2022-10-24; online 2022-10-24]
SciLifeLab Fellow
DOI Crossref
Barcode-free prediction of cell lineages from scRNA-seq datasets
Eisele AS, Tarbier M, Dormann AA, Pelechano V, Suter DM
- - (-) - [2022-09-20; online 2022-09-20]
DDLS Fellow Marcel Tarbier SciLifeLab Fellow
PubMed DOI Crossref
OPUSeq simplifies detection of low-frequency DNA variants and uncovers fragmentase-associated artifacts.
Alekseenko A, Wang J, Barrett D, Pelechano V
NAR Genomics and Bioinformatics 4 (2) lqac048 [2022-06-00; online 2022-06-27]
SciLifeLab Fellow
DOI Crossref
Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation
Li B, Zeis P, Alekseenko A, ..., Steinmetz LM, Pelechano V
- - (-) - [2022-05-05; online 2022-05-05]
SciLifeLab Fellow
PubMed DOI Crossref
Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Crowe-McAuliffe C, Murina V, Turnbull KJ, ..., Wilson DN, Hauryliuk V
Nat Commun 13 (1) 1860 [2022-04-06; online 2022-04-06]
SciLifeLab Fellow
PubMed DOI Crossref
Sample-to-answer COVID-19 nucleic acid testing using a low-cost centrifugal microfluidic platform with bead-based signal enhancement and smartphone read-out.
Soares RRG, Akhtar AS, Pinto IF, ..., Pelechano V, Russom A
Lab Chip 21 (15) 2932-2944 [2021-08-07; online 2021-06-11]
SciLifeLab Fellow
PubMed DOI Crossref
Rpb4 and Puf3 imprint and post-transcriptionally control the stability of a common set of mRNAs in yeast.
Garrido-Godino AI, Gupta I, Gutiérrez-Santiago F, ..., Pelechano V, Navarro F
RNA Biol 18 (8) 1206-1220 [2021-08-00; online 2020-11-01]
SciLifeLab Fellow
PubMed DOI Crossref
Simultaneous detection of SARS-CoV-2 and pandemic (H1N1) 2009 virus with real-time isothermal platform.
Yu L, Wang J, Li X, ..., Guo X, Yin X
Heliyon 7 (7) e07584 [2021-07-00; online 2021-07-15]
SciLifeLab Fellow
PubMed DOI Crossref
High-throughput 5'P sequencing enables the study of degradation-associated ribosome stalls.
Zhang Y, Pelechano V
Cell Rep Methods 1 (1) 100001 [2021-05-24; online 2021-04-02]
SciLifeLab Fellow
DOI Crossref
RNA degradation analysis reveals ribosome dynamics in complex microbiome samples
Huch S, Nersisyan L, Ropat M, ..., Engstrand L, Pelechano V
- - (-) - [2021-04-10; online 2021-04-10]
SciLifeLab Fellow
PubMed DOI Crossref
Direct detection of SARS-CoV-2 using non-commercial RT-LAMP reagents on heat-inactivated samples.
Alekseenko A, Barrett D, Pareja-Sanchez Y, ..., Yin X, Pelechano V
Sci Rep 11 (1) 1820 [2021-01-19; online 2021-01-19]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Improved computational analysis of ribosome dynamics from 5'P degradome data using fivepseq.
Nersisyan L, Ropat M, Pelechano V
NAR Genomics and Bioinformatics 2 (4) lqaa099 [2020-12-00; online 2020-11-24]
SciLifeLab Fellow
DOI Crossref
Point-of-care detection of SARS-CoV-2 in nasopharyngeal swab samples using an integrated smartphone-based centrifugal microfluidic platform
Soares RRG, Akhtar AS, Pinto IF, ..., Pelechano V, Russom A
- - (-) - [2020-11-06; online 2020-11-06]
SciLifeLab Fellow
PubMed DOI Crossref
TIF-Seq2 disentangles overlapping isoforms in complex human transcriptomes.
Wang J, Li B, Marques S, ..., Wei W, Pelechano V
Nucleic Acids Res. 48 (18) e104 [2020-10-09; online 2020-08-21]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
The RNA exosome shapes the expression of key protein-coding genes.
Wu M, Karadoulama E, Lloret-Llinares M, ..., Jensen TH, Sandelin A
Nucleic Acids Res. 48 (15) 8509-8528 [2020-09-04; online 2020-07-28]
SciLifeLab Fellow
DOI Crossref
Detection of SARS-CoV-2 using non-commercial RT-LAMP reagents and raw samples
Alekseenko A, Barrett D, Pareja-Sanchez Y, ..., Yin X, Pelechano V
- - (-) - [2020-08-24; online 2020-08-24]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
High-throughput 5’P sequencing enables the study of degradation-associated ribosome stalls
Zhang Y, Pelechano V
- - (-) - [2020-06-23; online 2020-06-23]
SciLifeLab Fellow
PubMed DOI Crossref
Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis.
Thomas QA, Ard R, Liu J, ..., Pelechano V, Marquardt S
Nat Commun 11 (1) 2589 [2020-05-22; online 2020-05-22]
SciLifeLab Fellow
DOI Crossref
Improved computational analysis of ribosome dynamics from 5’P degradome data using fivepeseq
Nersisyan L, Ropat M, Pelechano V
- - (-) - [2020-01-23; online 2020-01-23]
SciLifeLab Fellow
PubMed DOI Crossref
Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.
Wei W, Hennig BP, Wang J, ..., Steinmetz LM, Pelechano V
Genome Res 29 (12) 1974-1984 [2019-12-00; online 2019-11-18]
SciLifeLab Fellow
DOI Crossref
Dissecting chronic myeloid leukaemia overlapping transcriptome with TIF-Seq2
Wang J, Li B, Marques S, ..., Wei W, Pelechano V
- - (-) - [2019-11-29; online 2019-11-29]
SciLifeLab Fellow
DOI Crossref
Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination
Ard R, Thomas Q, Li B, ..., Pelechano V, Marquardt S
- - (-) - [2019-10-28; online 2019-10-28]
SciLifeLab Fellow
DOI Crossref
Chromatin-sensitive cryptic promoters encode alternative protein isoforms in yeast
Wei W, Hennig BP, Wang J, ..., Steinmetz LM, Pelechano V
- - (-) - [2018-08-29; online 2018-08-29]
SciLifeLab Fellow
PubMed DOI Crossref
The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock.
Garre E, Pelechano V, Sánchez Del Pino M, Alepuz P, Sunnerhagen P
PLoS Genet 14 (7) e1007563 [2018-07-00; online 2018-07-30]
Affiliated researcher SciLifeLab Fellow
DOI Crossref
Transcription-driven Chromatin Repression of Intragenic Promoters
Nielsen M, Ard R, Leng X, ..., Pelechano V, Marquardt S
- - (-) - [2018-03-09; online 2018-03-09]
SciLifeLab Fellow
PubMed DOI Crossref
From transcriptional complexity to cellular phenotypes: Lessons from yeast.
Pelechano V
Yeast 34 (12) 475-482 [2017-12-00; online 2017-10-11]
Affiliated researcher SciLifeLab Fellow
PubMed DOI Crossref
Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters.
Chen Y, Pai AA, Herudek J, ..., Jensen TH, Sandelin A
Nat. Genet. 48 (9) 984-994 [2016-09-00; online 2016-07-25]
Affiliated researcher SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Genome-wide quantification of 5'-phosphorylated mRNA degradation intermediates for analysis of ribosome dynamics.
Pelechano V, Wei W, Steinmetz LM
Nat Protoc 11 (2) 359-376 [2016-02-00; online 2016-01-28]
SciLifeLab Fellow Vicente Pelechano
SciLifeLab Data Centre
Publications 9.5.1