Schwenk JM

Family name	Schwenk
Given name	Jochen M
Initials	JM
ORCID	ORCID 0000-0001-8141-8449
Affiliations	Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology, Stockholm, Sweden.

46 publications

PubMed DOI Crossref

A standardized framework for circulating blood proteomics.

Cai X, Geyer PE, Perez-Riverol Y, ..., Völker U, Guo T

Nat. Genet. 57 (10) 2371-2380 [2025-10-00; online 2025-09-23]

PubMed DOI Crossref

A Biological-Systems-Based Analyses Using Proteomic and Metabolic Network Inference Reveals Mechanistic Insights into Hepatic Lipid Accumulation: An IMI-DIRECT Study.

Atabaki NN, Coral DE, Pomares-Millan H, ..., Viñuela A, Franks PW

medRxiv - (-) - [2025-06-02; online 2025-06-02]

PubMed DOI Crossref

The Circulating Proteome─Technological Developments, Current Challenges, and Future Trends.

Geyer PE, Hornburg D, Pernemalm M, ..., Deutsch EW, Schwenk JM

J. Proteome Res. 23 (12) 5279-5295 [2024-12-06; online 2024-10-31]

PubMed DOI Crossref

A roadmap to the molecular human linking multiomics with population traits and diabetes subtypes.

Halama A, Zaghlool S, Thareja G, ..., Schmidt F, Suhre K

Nat Commun 15 (1) 7111 [2024-08-19; online 2024-08-19]

PubMed DOI Crossref

Multiplexed mapping of the interactome of GPCRs with receptor activity-modifying proteins.

Kotliar IB, Bendes A, Dahl L, ..., Schwenk JM, Sakmar TP

Sci Adv 10 (31) eado9959 [2024-08-02; online 2024-07-31]

DOI Crossref

The Effect of Metformin Treatment on the Circulating Proteome

Connolly B, McCreight L, Slieker RC, ..., Gummesson A, Pearson ER

- - (-) - [2024-06-08; online 2024-06-08]

PubMed DOI Crossref

Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.

Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M, ..., Trégouët DA, Odeberg J

Nat Commun 14 (1) 7752 [2023-11-27; online 2023-11-27]

PubMed DOI Crossref

Expanding the GPCR-RAMP interactome.

Kotliar IB, Bendes A, Dahl L, ..., Schwenk JM, Sakmar TP

bioRxiv - (-) - [2023-11-23; online 2023-11-23]

PubMed DOI Crossref

Application of clinical and molecular profiling data to improve patient outcomes in psoriatic arthritis.

FitzGerald O, Behrens F, Barton A, ..., Vivekanantham A, Pennington SR

Ther Adv Musculoskelet Dis 15 (-) 1759720X231192315 [2023-09-08; online 2023-09-08]

PubMed DOI Crossref

Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits.

Brown AA, Fernandez-Tajes JJ, Hong MG, ..., Dermitzakis ET, Viñuela A

Nat Commun 14 (1) 5062 [2023-08-21; online 2023-08-21]

PubMed DOI Crossref

Author Correction: Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.

Allesøe RL, Lundgaard AT, Hernández Medina R, ..., Brunak S, IMI DIRECT Consortium

Nat. Biotechnol. 41 (7) 1026 [2023-07-00; online 2023-05-03]

PubMed DOI Crossref

Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.

Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M, ..., Trégouët DA, Odeberg J

Nat Commun 14 (1) 3280 [2023-06-07; online 2023-06-07]

PubMed DOI Crossref

Multiplexed selectivity screening of anti-GPCR antibodies.

Dahl L, Kotliar IB, Bendes A, ..., Sakmar TP, Schwenk JM

Sci Adv 9 (18) eadf9297 [2023-05-03; online 2023-05-03]

DOI Crossref

Evaluation of Circulating Plasma Proteins in Breast Cancer: A Mendelian Randomization Analysis

Malarstig A, Grassman F, Dahl L, ..., Czene K, Hedman A

- - (-) - [2023-04-04; online 2023-04-04]

PubMed DOI Crossref

Elucidating the Interactome of G Protein-Coupled Receptors and Receptor Activity-Modifying Proteins.

Kotliar IB, Lorenzen E, Schwenk JM, Hay DL, Sakmar TP

Pharmacol Rev 75 (1) 1-34 [2023-01-00; online 2022-12-08]

DOI Crossref

Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins (RAMPs)

Kotliar IB, Ceraudo E, Kemelmakher-Liben K, ..., Schwenk JM, Sakmar TP

- - (-) - [2022-12-06; online 2022-12-06]

DOI Crossref

Multiplexed selectivity screening of anti-GPCR antibodies

Dahl L, Kotliar IB, Bendes A, ..., Sakmar TP, Schwenk JM

- - (-) - [2022-11-24; online 2022-11-24]

PubMed DOI Crossref

Advances in plasma proteomics: Moving from technology to precision medicine.

Yu X, Schwenk JM, Xu P, LaBaer J

Proteomics Clin Appl 16 (6) e2200083 [2022-11-00; online 2022-11-16]

PubMed DOI Crossref

Omics and Multi-Omics Analysis for the Early Identification and Improved Outcome of Patients with Psoriatic Arthritis.

Gurke R, Bendes A, Bowes J, ..., Pennington SR, HIPPOCRATES Consortium

Biomedicines 10 (10) - [2022-09-24; online 2022-09-24]

DOI Crossref

Elevated plasma Complement Factor H Regulating Protein 5 is associated with venous thromboembolism and COVID-19 severity

Sanchez-Rivera L, Iglesias MJ, Ibrahim-Kosta M, ..., Trégouët DA, Odeberg J

- - (-) - [2022-04-21; online 2022-04-21]

PubMed DOI Crossref

Advances and Utility of the Human Plasma Proteome.

Deutsch EW, Omenn GS, Sun Z, ..., Moritz RL, Schwenk JM

J. Proteome Res. 20 (12) 5241-5263 [2021-12-03; online 2021-10-21]

DOI Crossref

Precise blood proteome profiling in an undiagnosed population with COVID-19

Fredolini C, Dodig-Crnković T, Bendes A, ..., Roxhed N, Schwenk JM

- - (-) - [2021-11-16; online 2021-11-16]

PubMed DOI Crossref

Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients.

Zeybel M, Altay O, Arif M, ..., Borén J, Mardinoglu A

Mol Syst Biol 17 (10) e10459 [2021-10-00; online 2021-10-26]

Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

PubMed DOI Crossref

Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2.

Roxhed N, Bendes A, Dale M, ..., Fredolini C, Schwenk JM

Nat Commun 12 (1) 3695 [2021-06-17; online 2021-06-17]

SciLifeLab Fellow Simon Elsässer

DOI Crossref

Combined Metabolic Activators Reduces Liver Fat in Nonalcoholic Fatty Liver Disease Patients

Zeybel M, Altay O, Arif M, ..., Borén J, Mardinoglu A

- - (-) - [2021-05-23; online 2021-05-23]

DOI Crossref

Circulating proteins reveal prior use of menopausal hormonal therapy and increased risk of breast cancer

Thomas CE, Dahl L, Byström S, ..., Schwenk JM, Gabrielson M

- - (-) - [2021-05-22; online 2021-05-22]

DOI Crossref

Genetic analysis of blood molecular phenotypes reveals regulatory networks affecting complex traits: a DIRECT study

Viñuela A, Brown AA, Fernandez J, ..., Pearson ER, Dermitzakis ET

- - (-) - [2021-03-29; online 2021-03-29]

DOI Crossref

Identification of endothelial-derived proteins in plasma associated with cardiovascular risk factors

Iglesias M, Kruse L, Sanchez-Rivera L, ..., Odeberg J, Butler L

- - (-) - [2021-02-09; online 2021-02-09]

PubMed DOI Crossref

Enhanced Validation of Antibodies Enables the Discovery of Missing Proteins.

Sivertsson Å, Lindström E, Oksvold P, ..., Uhlén M, Lindskog C

J. Proteome Res. 19 (12) 4766-4781 [2020-12-04; online 2020-11-10]

PubMed DOI Crossref

Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes: An IMI-DIRECT study.

Obura M, Beulens JWJ, Slieker R, ..., Rutters F, IMI-DIRECT Consortium

PLoS ONE 15 (11) e0242360 [2020-11-30; online 2020-11-30]

PubMed DOI Crossref

Integration of molecular profiles in a longitudinal wellness profiling cohort.

Tebani A, Gummesson A, Zhong W, ..., Uhlen M, Fagerberg L

Nat Commun 11 (1) 4487 [2020-09-08; online 2020-09-08]

Adil Mardinoglu SciLifeLab Fellow

DOI Crossref

A translational multiplex serology approach to profile the prevalence of anti-SARS-CoV-2 antibodies in home-sampled blood

Roxhed N, Bendes A, Dale M, ..., Fredolini C, Schwenk JM

- - (-) - [2020-07-02; online 2020-07-02]

DOI Crossref

Facets of individual-specific health signatures determined from longitudinal plasma proteome profiling

Dodig-Crnković T, Hong MG, Thomas CE, ..., Uhlén M, Schwenk JM

- - (-) - [2020-03-15; online 2020-03-15]

DOI Crossref

Predicting and elucidating the etiology of fatty liver disease using a machine learning-based approach: an IMI DIRECT study

Atabaki-Pasdar N, Ohlsson M, Viñuela A, ..., Pavo I, Franks PW

- - (-) - [2020-02-11; online 2020-02-11]

PubMed DOI Crossref

Progress on Identifying and Characterizing the Human Proteome: 2019 Metrics from the HUPO Human Proteome Project.

Omenn GS, Lane L, Overall CM, ..., Baker MS, Deutsch EW

J. Proteome Res. 18 (12) 4098-4107 [2019-12-06; online 2019-09-13]

PubMed DOI Crossref

The human secretome.

Uhlén M, Karlsson MJ, Hober A, ..., Fagerberg L, Sivertsson Å

Sci Signal 12 (609) eaaz0274 [2019-11-26; online 2019-11-26]

Adil Mardinoglu SciLifeLab Fellow

DOI Crossref

Mass Spectrometry-Based Plasma Proteomics: Considerations from Sample Collection to Achieving Translational Data

Ignjatovic V, Geyer PE, Palaniappan KK, ..., Deutsch EW, Schwenk JM

- - (-) - [2019-07-26; online 2019-07-26]

PubMed DOI Crossref

In-depth human plasma proteome analysis captures tissue proteins and transfer of protein variants across the placenta.

Pernemalm M, Sandberg A, Zhu Y, ..., Westgren M, Lehtiö J

Elife 8 (-) - [2019-04-08; online 2019-04-08]

DOI Crossref

Multiplexed Analysis of the Secretin-like GPCR-RAMP Interactome

Lorenzen E, Dodig-Crnković T, Kotliar IB, ..., Schwenk JM, Sakmar TP

- - (-) - [2019-04-06; online 2019-04-06]

DOI Crossref

Author response: In-depth human plasma proteome analysis captures tissue proteins and transfer of protein variants across the placenta

Pernemalm M, Sandberg A, Zhu Y, ..., Westgren M, Lehtiö J

- - (-) - [2019-02-13; online 2019-02-13]

DOI Crossref

Systematic Development of Sandwich Immunoassays for the Plasma Secretome

Häussler RS, Bendes A, Iglesias M, ..., Qundos U, Schwenk JM

- - (-) - [2019-01-08; online 2019-01-08]

DOI Crossref

Screening a Resource of Recombinant Protein Fragments for Targeted Proteomics

Edfors F, Forsström B, Vunk H, ..., Schwenk JM, Uhlen M

- - (-) - [2018-11-19; online 2018-11-19]

DOI Crossref

Profiles of circulating histidine-rich glycoprotein associate with chronological age and risk of all-cause mortality

Hong MG, Dodig-Crnković T, Chen X, ..., Magnusson PKE, Schwenk JM

- - (-) - [2018-11-09; online 2018-11-09]

DOI Crossref

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: an overview of the data from the epidemiological studies within the IMI DIRECT Consortium

Koivula RW, Forgie IM, Kurbasic A, ..., Pearson E, Franks PW

- - (-) - [2018-04-16; online 2018-04-16]

PubMed DOI Crossref

A pathology atlas of the human cancer transcriptome.

Uhlen M, Zhang C, Lee S, ..., Mardinoglu A, Ponten F

Science (New York, N.Y.) 357 (6352) eaan2507 [2017-08-18; online 2017-08-19]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow

PubMed DOI Crossref

A subcellular map of the human proteome.

Thul PJ, Åkesson L, Wiking M, ..., Uhlén M, Lundberg E

Science (New York, N.Y.) 356 (6340) eaal3321 [2017-05-26; online 2017-05-11]

Adil Mardinoglu Affiliated researcher SciLifeLab Fellow