ACS Med. Chem. Lett.

From Virtual Screens to Cellular Target Engagement: New Small Molecule Ligands for the Immune Checkpoint LAG-3.

Fuchs N, Calvo-Barreiro L, Talagayev V, ..., Wolber G, Gabr MT

ACS Med. Chem. Lett. 15 (11) 1884-1890 [2024-11-14; online 2024-10-15]

Exploring Non-orthosteric Interactions with a Series of Potent and Selective A3 Antagonists.

Miranda-Pastoriza D, Bernárdez R, Azuaje J, ..., Gutiérrez-de-Terán H, Sotelo E

ACS Med. Chem. Lett. 13 (2) 243-249 [2022-02-10; online 2022-01-10]

Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor.

Mpakali A, Saridakis E, Giastas P, ..., Hallberg M, Stratikos E

ACS Med. Chem. Lett. 11 (7) 1429-1434 [2020-07-09; online 2020-06-02]

Molecular Docking Studies of Royleanone Diterpenoids from Plectranthus spp. as P-Glycoprotein Inhibitors.

Isca VMS, Ferreira RJ, Garcia C, ..., Afonso CAM, Rijo P

ACS Med. Chem. Lett. 11 (5) 839-845 [2020-05-14; online 2020-03-12]

N-Trifluoromethylthiolated Sulfonimidamides and Sulfoximines: Anti-microbial, Anti-mycobacterial, and Cytotoxic Activity.

Thota N, Makam P, Rajbongshi KK, ..., Naicker T, Arvidsson PI

ACS Med. Chem. Lett. 10 (10) 1457-1461 [2019-10-10; online 2019-09-11]

Design of Selective sPLA2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid.

Giordanetto F, Knerr L, Nordberg P, ..., Jansen F, Ahlqvist M

ACS Med. Chem. Lett. 9 (7) 600-605 [2018-07-12; online 2018-06-23]

Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors.

Knerr L, Giordanetto F, Nordberg P, ..., Roth RG, Ahlqvist M

ACS Med. Chem. Lett. 9 (7) 594-599 [2018-07-12; online 2018-06-23]

Structure–Activity Relationships and Molecular Modeling of 1,2,4-Triazoles as Adenosine Receptor Antagonists

Carlsson J, Tosh DK, Phan K, Gao ZG, Jacobson KA

ACS Med. Chem. Lett. 3 (9) 715-720 [2012-09-13; online 2012-08-07]

Jens Carlsson SciLifeLab Fellow