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J Med Chem
JSON
ISSN
1520-4804
ISSN-L
0022-2623
IUID
7741c10bf77a4052bf534e8c8c1baabf
Modified
2020-11-27T13:12:54.662Z
Created
2020-11-06T09:01:34.307Z
Year 2022
PubMed
DOI
Crossref
Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction.
Begnini F,
Geschwindner S
, Johansson P, ...,
Schiesser S
,
Kihlberg J
J Med Chem
65
(4) 3473-3517 [2022-02-24; online 2022-02-02]
Jens Carlsson
SciLifeLab Fellow
Year 2021
PubMed
DOI
Crossref
Optimization of an Imidazo[1,2-a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy.
McCoull W
, Boyd S, Brown MR, ..., Zhu Q, Smith PD
J Med Chem
64
(18) 13524-13539 [2021-09-23; online 2021-09-03]
SciLifeLab Fellow
Yumeng Mao
Year 2020
PubMed
DOI
Crossref
Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase.
Degorce SL
,
Tavana O
, Banks E, ..., Yang B, Edmondson SD
J Med Chem
63
(18) 10460-10473 [2020-09-24; online 2020-09-14]
SciLifeLab Fellow
Yumeng Mao
PubMed
DOI
Crossref
Docking Finds GPCR Ligands in Dark Chemical Matter.
Ballante F
, Rudling A, Zeifman A, ..., Loza MI,
Carlsson J
J Med Chem
63
(2) 613-620 [2020-01-23; online 2020-01-13]
Jens Carlsson
SciLifeLab Fellow
Year 2018
PubMed
DOI
Crossref
Docking Screens for Dual Inhibitors of Disparate Drug Targets for Parkinson's Disease.
Jaiteh M, Zeifman A, Saarinen M, ..., Loza MI,
Carlsson J
J Med Chem
61
(12) 5269-5278 [2018-06-28; online 2018-06-15]
Affiliated researcher
Jens Carlsson
SciLifeLab Fellow
Year 2017
PubMed
DOI
Crossref
Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space.
Rudling A, Gustafsson R, Almlöf I, ..., Stenmark P,
Carlsson J
J Med Chem
60
(19) 8160-8169 [2017-10-12; online 2017-10-03]
Affiliated researcher
Jens Carlsson
SciLifeLab Fellow
Year 2015
PubMed
DOI
Crossref
Fragment-Based Discovery of Subtype-Selective Adenosine Receptor Ligands from Homology Models.
Ranganathan A, Stoddart LA, Hill SJ, Carlsson J
J Med Chem
58
(24) 9578-9590 [2015-12-24; online 2015-12-08]
Affiliated researcher
Jens Carlsson
SciLifeLab Fellow
SciLifeLab Data Centre
Publications
9.5.1