Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines.

Lin W, Yang Z, Kaur A, Block A, Vujasinovic M, Löhr JM, Globisch D

RSC Chem Biol 2 (5) 1479-1483 [2021-10-07; online 2021-08-12]

The investigation of microbiome-derived metabolites is important to understand metabolic interactions with their human host. New methodologies for mass spectrometric discovery of undetected metabolites with unknown bioactivity are required. Herein, we introduce squaric acid as a new chemoselective moiety for amine metabolite analysis in human fecal samples.

Daniel Globisch

SciLifeLab Fellow

PubMed 34704052

DOI 10.1039/d1cb00132a

Crossref 10.1039/d1cb00132a

pii: d1cb00132a
pmc: PMC8496035

Publications 9.5.0